PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 8435210-1 1993 Vincristine binding to solutions of alpha 1-acid glycoprotein (AGP, 2 mg/ml) and the effect of D,L-verapamil, verapamil enantiomers and the verapamil metabolites norverapamil and D617 were investigated in vitro using equilibrium dialysis and 3H-labelled vincristine. Vincristine 0-11 orosomucoid 2 Homo sapiens 63-69 11452244-11 2001 CONCLUSIONS: The disposition of the active enantiomer, R -methadone, can be predicted in part by CYP3A activity and protein binding to alpha1-AGP (ORM2), whereas S-methadone disposition is not well explained by the factors examined in this study. Methadone 55-67 orosomucoid 2 Homo sapiens 147-151 16290938-1 2006 Coumarin-type anticoagulants, warfarin, phenprocoumon and acenocoumarol, were tested for their stereoselective binding to the human orosomucoid (ORM; AGP) genetic variants ORM 1 and ORM 2. Acenocoumarol 58-71 orosomucoid 2 Homo sapiens 182-187 15938635-11 2005 When the Agp2 apoprotein was assembled with the ZZE form of biliverdin, the formation of the final adduct was accelerated compared to the formation of the ZZZ control, indicating that the ZZE chromophore fits directly into the chromophore pocket of Agp2. Biliverdine 60-70 orosomucoid 2 Homo sapiens 9-13 15938635-11 2005 When the Agp2 apoprotein was assembled with the ZZE form of biliverdin, the formation of the final adduct was accelerated compared to the formation of the ZZZ control, indicating that the ZZE chromophore fits directly into the chromophore pocket of Agp2. Biliverdine 60-70 orosomucoid 2 Homo sapiens 249-253 1874742-5 1991 Methylation analysis showed that AGP-(a) and AGP-(b) were both highly branched 3,6-galactans with terminal arabinofuranosyl substituents. 3,6-galactans 79-92 orosomucoid 2 Homo sapiens 45-51 1874742-5 1991 Methylation analysis showed that AGP-(a) and AGP-(b) were both highly branched 3,6-galactans with terminal arabinofuranosyl substituents. arabinofuranosyl 107-123 orosomucoid 2 Homo sapiens 45-51 1874742-7 1991 The amino-terminal sequence of AGP-(b) contained an alanine-hydroxyproline repeat. Alanine 52-59 orosomucoid 2 Homo sapiens 31-37 1874742-7 1991 The amino-terminal sequence of AGP-(b) contained an alanine-hydroxyproline repeat. Hydroxyproline 60-74 orosomucoid 2 Homo sapiens 31-37 34117927-9 2021 The AGP2 gene, which encodes ADP-glucose pyrophosphorylase determining TGW, was found by haplotype analysis in the Forno/Oberkulmer population to affect grain number oppositely, indicating this trade-off at the gene level. Glucose 33-40 orosomucoid 2 Homo sapiens 4-8 34570488-5 2021 Resonance Raman and IR spectroscopic analyses revealed that both pCNF-substituted variants undergo the same photoinduced structural changes as wild-type Agp2. pcnf 65-69 orosomucoid 2 Homo sapiens 153-157 2311335-6 1990 When concentrations of AAG variants were considered, a significant correlation was obtained between the binding ratio of dl-methadone and orosomucoid2 A concentration (r = 0.715; p less than 0.001), a weak correlation between dl-methadone and orosomucoid1 S concentration (r = 0.494; p less than 0.001), and no correlation between dl-methadone and orosomucoid1 F1 concentration (r = 0.049; not significant). Methadone 121-133 orosomucoid 2 Homo sapiens 138-150 3402460-12 1988 It was shown that about 90% of the biantennary glycans of both AGP-B and AGP-C were disialylated while the remainder were monosialylated. Polysaccharides 47-54 orosomucoid 2 Homo sapiens 63-68 35107292-3 2022 Focusing on the Ag-Pb-Si-S and Ag-Sr-Sn-S systems, we show that one structure type, with the formulas Ag2Pb3Si2S8 and Ag2Sr3Sn2S8, is favored. Silicon 22-26 orosomucoid 2 Homo sapiens 16-21 34041904-6 2021 Inoculation with 2.5% of a methanogenic benzene-degrading consortium containing Sva0485 (Deltaproteobacteria ORM2) resulted in benzene biodegradation in the presence of sulfate or under methanogenic conditions. Benzene 40-47 orosomucoid 2 Homo sapiens 109-113 34041904-6 2021 Inoculation with 2.5% of a methanogenic benzene-degrading consortium containing Sva0485 (Deltaproteobacteria ORM2) resulted in benzene biodegradation in the presence of sulfate or under methanogenic conditions. Benzene 127-134 orosomucoid 2 Homo sapiens 109-113 34041904-6 2021 Inoculation with 2.5% of a methanogenic benzene-degrading consortium containing Sva0485 (Deltaproteobacteria ORM2) resulted in benzene biodegradation in the presence of sulfate or under methanogenic conditions. Sulfates 169-176 orosomucoid 2 Homo sapiens 109-113 33184417-7 2020 The impaired triglycerides transport, glucose uptake, and consequent insulin resistance are mostly affected by faulted lipid metabolism (APOM, APOD, APOH, APOC1) and encouraged by oxidative stress (CP, TF, ORM2) and inflammation (CFH, CFB, CLU) as a secondary response accompanied by changes in matrix architecture (AFM, FBLN1, AMBP). Triglycerides 13-26 orosomucoid 2 Homo sapiens 206-210 32148378-12 2020 Gene Set Enrichment Analysis (GSEA) was employed to explore the ORM2-associated signaling network. gsea 30-34 orosomucoid 2 Homo sapiens 64-68 32148378-20 2020 GSEA analysis of ORM2 from The Cancer Genome Atlas liver cancer data identified that ORM2 positively associated with the G2/M checkpoint, E2F target signaling, as well as Wnt/beta-catenin and Hedgehog signaling. gsea 0-4 orosomucoid 2 Homo sapiens 17-21 32148378-20 2020 GSEA analysis of ORM2 from The Cancer Genome Atlas liver cancer data identified that ORM2 positively associated with the G2/M checkpoint, E2F target signaling, as well as Wnt/beta-catenin and Hedgehog signaling. gsea 0-4 orosomucoid 2 Homo sapiens 85-89 27760464-6 2016 165 site-specific N-glycopeptides representative of all N-glycosylation sites were identified from AGP 1 and AGP 2 isoforms. n-glycopeptides 18-33 orosomucoid 2 Homo sapiens 109-114 31844056-0 2019 Colloidal silver diphosphide (AgP2) nanocrystals as low overpotential catalysts for CO2 reduction to tunable syngas. Silver 10-28 orosomucoid 2 Homo sapiens 30-34 31844056-0 2019 Colloidal silver diphosphide (AgP2) nanocrystals as low overpotential catalysts for CO2 reduction to tunable syngas. Carbon Dioxide 84-87 orosomucoid 2 Homo sapiens 30-34 31844056-3 2019 We synthesize AgP2 nanocrystals (NCs) with a greater than 3-fold reduction in overpotential for electrochemical CO2-to-CO reduction compared to Ag and greatly enhanced stability. Carbon Dioxide 112-115 orosomucoid 2 Homo sapiens 14-18 31844056-3 2019 We synthesize AgP2 nanocrystals (NCs) with a greater than 3-fold reduction in overpotential for electrochemical CO2-to-CO reduction compared to Ag and greatly enhanced stability. Carbon Dioxide 112-114 orosomucoid 2 Homo sapiens 14-18 31844056-5 2019 In situ X-ray absorption spectroscopy (XAS) shows that a maximum Faradaic efficiency is achieved at an average silver valence state of +1.08 in AgP2 NCs. Silver 111-117 orosomucoid 2 Homo sapiens 144-148 31844056-6 2019 A photocathode consisting of a n+p-Si wafer coated with ultrathin Al2O3 and AgP2 NCs achieves an onset potential of 0.2 V vs. RHE for CO production and a partial photocurrent density for CO at -0.11 V vs. RHE (j-0.11, CO) of -3.2 mA cm-2. Carbon Dioxide 134-136 orosomucoid 2 Homo sapiens 76-80 31844056-6 2019 A photocathode consisting of a n+p-Si wafer coated with ultrathin Al2O3 and AgP2 NCs achieves an onset potential of 0.2 V vs. RHE for CO production and a partial photocurrent density for CO at -0.11 V vs. RHE (j-0.11, CO) of -3.2 mA cm-2. Carbon Dioxide 187-189 orosomucoid 2 Homo sapiens 76-80 31844056-6 2019 A photocathode consisting of a n+p-Si wafer coated with ultrathin Al2O3 and AgP2 NCs achieves an onset potential of 0.2 V vs. RHE for CO production and a partial photocurrent density for CO at -0.11 V vs. RHE (j-0.11, CO) of -3.2 mA cm-2. Carbon Dioxide 187-189 orosomucoid 2 Homo sapiens 76-80 30295034-7 2018 From pooled human plasma, we find 90, 101, and 64 different glycan compositions for genetic variants ORM1*F1, ORM1*S, and ORM2, respectively. Polysaccharides 60-66 orosomucoid 2 Homo sapiens 122-126 29901122-12 2018 ORM2, S100A9, IL-36alpha and SOD1 were associated with the development of TB, and have the potential to distinguish between different stages of TB. Terbium 74-76 orosomucoid 2 Homo sapiens 0-4 29901122-12 2018 ORM2, S100A9, IL-36alpha and SOD1 were associated with the development of TB, and have the potential to distinguish between different stages of TB. Terbium 144-146 orosomucoid 2 Homo sapiens 0-4 29178800-6 2018 Dechlorination could not be attributed to known dechlorinators Dehalobacter or Dehalococcoides, while anaerobic benzene degradation was mediated by microbes affiliated to a Deltaproteobacterium ORM2, previously associated with this activity. Benzene 112-119 orosomucoid 2 Homo sapiens 194-198 27760464-6 2016 165 site-specific N-glycopeptides representative of all N-glycosylation sites were identified from AGP 1 and AGP 2 isoforms. Nitrogen 18-19 orosomucoid 2 Homo sapiens 109-114 27299732-5 2016 Starch accumulation and Agp2 expression in wheat grains reached their peak at 21 and 15 days post anthesis (DPA), respectively. dpa 108-111 orosomucoid 2 Homo sapiens 24-28 23737533-6 2013 Moreover, sphingolipid synthesis is regulated in response to endoplasmic reticulum (ER) stress by activation of a calcium- and calcineurin-dependent pathway via transcriptional induction of ORM2. Calcium 114-121 orosomucoid 2 Homo sapiens 190-194 26351173-6 2016 Orosomucoid 2 >1.81 microg/mg of creatinine could distinguish SRNS-FSGS from SRNS-MCD [AUC 0.84 (CI 0.62-1.0), sensitivity 90 % and specificity 85.5 %]. Creatinine 36-46 orosomucoid 2 Homo sapiens 0-13 24389491-6 2014 For ORM1 and ORM2 DEL constructs, significantly increased activities after dexamethasone (DEX) treatments (alone and combined with interleukin (IL)-1beta) were observed. Dexamethasone 75-88 orosomucoid 2 Homo sapiens 13-17 24389491-6 2014 For ORM1 and ORM2 DEL constructs, significantly increased activities after dexamethasone (DEX) treatments (alone and combined with interleukin (IL)-1beta) were observed. Dexamethasone 90-93 orosomucoid 2 Homo sapiens 13-17 24389491-7 2014 Significantly higher FULL construct activities than DEL construct activities were observed for ORM1 after IL-1beta treatment, while those for ORM2 were significantly lower at basal level and after DEX treatments. Dexamethasone 197-200 orosomucoid 2 Homo sapiens 142-146 23737533-3 2013 The recently discovered SPT-associated proteins, Orm1 and Orm2, are critical regulators of sphingolipids. Sphingolipids 91-104 orosomucoid 2 Homo sapiens 58-62 23737533-6 2013 Moreover, sphingolipid synthesis is regulated in response to endoplasmic reticulum (ER) stress by activation of a calcium- and calcineurin-dependent pathway via transcriptional induction of ORM2. Sphingolipids 10-22 orosomucoid 2 Homo sapiens 190-194 23711709-4 2013 RESULTS: Of them, 82 were mapped in proximity to known or previously predicted genes; 7 were randomly picked up for further confirmation by ChIP-PCR and 3 genes (GALM, ITPR2 and ORM2) were found to be specifically up-regulated in the ATRA-treated NB4 cells, indicating that they might be the down-stream target genes of ATRA. Tretinoin 234-238 orosomucoid 2 Homo sapiens 178-182 23711709-4 2013 RESULTS: Of them, 82 were mapped in proximity to known or previously predicted genes; 7 were randomly picked up for further confirmation by ChIP-PCR and 3 genes (GALM, ITPR2 and ORM2) were found to be specifically up-regulated in the ATRA-treated NB4 cells, indicating that they might be the down-stream target genes of ATRA. Tretinoin 320-324 orosomucoid 2 Homo sapiens 178-182