PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
24595680-10	2014	The Km values of CYP3A8 and CYP3A5 for 4beta-hydroxycholesterol formation from cholesterol were 204 and 104 muM, respectively, and Vmax values were 0.600 and 0.310 pg/pmol/min, respectively.	cholest-5-ene-3,4-diol	39-63	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	28-34
24595680-10	2014	The Km values of CYP3A8 and CYP3A5 for 4beta-hydroxycholesterol formation from cholesterol were 204 and 104 muM, respectively, and Vmax values were 0.600 and 0.310 pg/pmol/min, respectively.	Cholesterol	52-63	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	28-34
20814160-2	2010	Low activities for dealkylation of ethoxyresorufin and pentoxyresorufin were seen in recombinant monkey mfCYP3A4 and mfCYP3A5 and in recombinant human CYP3A4 and CYP3A5 expressed in bacterial membranes.	ethoxyresorufin	35-50	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	117-125
20814160-2	2010	Low activities for dealkylation of ethoxyresorufin and pentoxyresorufin were seen in recombinant monkey mfCYP3A4 and mfCYP3A5 and in recombinant human CYP3A4 and CYP3A5 expressed in bacterial membranes.	pentoxyresorufin	55-71	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	117-125
20814160-3	2010	Hydroxylation activities of mfCYP3A4 and mfCYP3A5 toward coumarin, paclitaxel, diclofenac, flurbiprofen, and S-mephenytoin were below detectable levels, as was also true for CYP3A4 and CYP3A5.	coumarin	57-65	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	41-49
24595680-9	2014	The formation of 4beta-hydroxycholesterol from cholesterol was specifically mediated by recombinant cynomolgus CYP3A8 and CYP3A5.	cholest-5-ene-3,4-diol	17-41	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	122-128
24595680-9	2014	The formation of 4beta-hydroxycholesterol from cholesterol was specifically mediated by recombinant cynomolgus CYP3A8 and CYP3A5.	Cholesterol	30-41	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	122-128
20814160-3	2010	Hydroxylation activities of mfCYP3A4 and mfCYP3A5 toward coumarin, paclitaxel, diclofenac, flurbiprofen, and S-mephenytoin were below detectable levels, as was also true for CYP3A4 and CYP3A5.	Paclitaxel	67-77	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	41-49
20814160-3	2010	Hydroxylation activities of mfCYP3A4 and mfCYP3A5 toward coumarin, paclitaxel, diclofenac, flurbiprofen, and S-mephenytoin were below detectable levels, as was also true for CYP3A4 and CYP3A5.	Diclofenac	79-89	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	41-49
20814160-3	2010	Hydroxylation activities of mfCYP3A4 and mfCYP3A5 toward coumarin, paclitaxel, diclofenac, flurbiprofen, and S-mephenytoin were below detectable levels, as was also true for CYP3A4 and CYP3A5.	Flurbiprofen	91-103	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	41-49
20814160-3	2010	Hydroxylation activities of mfCYP3A4 and mfCYP3A5 toward coumarin, paclitaxel, diclofenac, flurbiprofen, and S-mephenytoin were below detectable levels, as was also true for CYP3A4 and CYP3A5.	Mephenytoin	109-122	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	41-49
20814160-4	2010	Monkey mfCYP3A5 and mfCYP3A4 were highly active in bufuralol 1"-hydroxylation.	bufuralol	51-60	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	7-15
20814160-5	2010	mfCYP3A5 was efficient at dextromethorphan O-demethylation, although human CYP3A5 was unable to catalyze this reaction.	Dextromethorphan	26-42	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	0-8
20814160-6	2010	Apparent bufuralol 1"-hydroxylation and dextromethorphan O-demethylation activities of monkey liver microsomes were higher than those of human liver microsomes, possibly because of contributions of mfCYP3A5 to these P450 2D-dependent drug oxidations.	bufuralol	9-18	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	198-206
20814160-7	2010	mfCYP3A5 and CYP3A5 catalyzed midazolam 1"-hydroxylation at a low substrate concentration more efficiently than the corresponding CYP3A4.	Midazolam	30-39	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	0-8
20814160-8	2010	mfCYP3A5 had higher testosterone 6beta-hydroxylase activity than mfCYP3A4, but the reverse relationship was observed in oxidation of nifedipine and hydroxylation of dexamethasone.	Nifedipine	133-143	cytochrome P450 family 3 subfamily A member 5	Macaca fascicularis	0-8