PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
19420447-7	2009	The vertical rate of growth can reach 300 nm min(-1) in an environment containing argon, hydrogen, and traces of water vapour.	Argon	82-87	CD59 molecule (CD59 blood group)	Homo sapiens	45-51
19420447-7	2009	The vertical rate of growth can reach 300 nm min(-1) in an environment containing argon, hydrogen, and traces of water vapour.	Hydrogen	89-97	CD59 molecule (CD59 blood group)	Homo sapiens	45-51
19420447-7	2009	The vertical rate of growth can reach 300 nm min(-1) in an environment containing argon, hydrogen, and traces of water vapour.	Water	113-118	CD59 molecule (CD59 blood group)	Homo sapiens	45-51
19010979-6	2009	Oxygen transfer capacity averaged 41.7+/-20.8 mL x min(-1), carbon dioxide removal was 148.0+/-63.4 mL x min(-1).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	51-57
19010979-6	2009	Oxygen transfer capacity averaged 41.7+/-20.8 mL x min(-1), carbon dioxide removal was 148.0+/-63.4 mL x min(-1).	Carbon Dioxide	60-74	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
18697806-3	2009	Baseline and adenosine-induced (140 microg x kg(-1) x min(-1)) hyperaemic MBF was analysed according to a three-coronary-artery-territory model.	Adenosine	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	54-60
18938097-7	2009	Vancomycin (MIC(50)/MIC(90), 1/1 microg/ml) and linezolid (MIC(50)/MIC(90), 2/2 microg/ml) showed similar potency, and overall susceptibility rates for the three antibiotics were 99.8-100.0% susceptible.	Vancomycin	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	20-32
19118158-7	2009	results: Indo significantly reduced the CO(2) reserve required to produce apnea from 6.3 +/- 0.5 to 4.4 +/- 0.7 mmHg (P = 0.01) and increased the slope of the ventilation decrease in response to hypocapnic inhibition below eupnea (control vs. Indo: 1.06 +/- 0.10 vs. 1.61 +/- 0.27 l x min(-1) x mmHg(-1), P < 0.05).	Indomethacin	9-13	CD59 molecule (CD59 blood group)	Homo sapiens	285-291
19402515-4	2009	The results revealed that, under the condition of 10.0% GAC, 800 W microwave power, 0.08 MPa absolute pressure and 150 mL x min(-1) carrier gas (N2) flow-rate, more than 99% oil removal could be obtained within 15 min using this microwave thermal remediation enhanced by GAC; at the same time, about 91% of the oil contaminant could be recovered without significant changes in chemical composition.	Oils	174-177	CD59 molecule (CD59 blood group)	Homo sapiens	124-130
19100670-10	2009	The decrease in renal plasma flow in response to N-monomethyl-l-arginine infusion was more pronounced at follow-up (-56.7 +/- 39 versus -73.4 +/- 48 mL/min/1.73 m(2); P = 0.02), indicating improved basal NO activity.	omega-N-Methylarginine	49-72	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
19151272-6	2009	Anesthesia was induced with propofol 2.0 mg/kg and was maintained with a continuous infusion of propofol at a rate of 100-167 microg x kg(-1) x min(-1).	Propofol	96-104	CD59 molecule (CD59 blood group)	Homo sapiens	144-150
18575955-4	2009	The sampling rates for formic acid concentrations of 128 microg m(-3) and 1248 microg m(-3) were determined to be 91.2 +/- 3.9 ml min(-1) and 111.6 +/- 2.8 ml min(-1), respectively.	formic acid	23-34	CD59 molecule (CD59 blood group)	Homo sapiens	130-136
18575955-5	2009	The acetic acid sampling rate was independent of the concentration in the range 160 microg m(-3)-1564 microg m(-3), and amounted to 97.3 +/- 3.1 ml min(-1).	Acetic Acid	4-15	CD59 molecule (CD59 blood group)	Homo sapiens	148-154
19156973-9	2009	RESULTS: The pharmacokinetics of rocuronium in DMD patients were Vc 63 +/- 14 ml kg(-1), Cl 3.0 +/- 1.0 ml min(-1) kg(-1), half-lives 2.0 +/- 0.6, 20 +/- 10 and 129 +/- 98 min, SE.	Rocuronium	33-43	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
19154662-1	2009	The regulatory proteins CD55 and CD59 are glycolsylphosphatidylinositol-anchored, type I cell surface proteins, which inhibit formation of the C3 convertases and prevent the terminal polymerization of the membrane attack complexes, respectively.	glycolsylphosphatidylinositol	42-71	CD59 molecule (CD59 blood group)	Homo sapiens	33-37
19154662-2	2009	Paroxysmal nocturnal hemoglobinuria (PNH) is a genetic disorder due to the impaired conformation of the glycolsylphosphatidylinositol anchor, which results in the deficient expression of CD55 and CD59 leading to excessive destruction of red cells and leukocytes.	glycolsylphosphatidylinositol	104-133	CD59 molecule (CD59 blood group)	Homo sapiens	196-200
19154662-10	2009	We conclude that the diminished expression of the glycolsylphosphatidylinositol-anchored type I cell surface proteins CD55 and CD59 is not specific to PNH and that it can be found in patients with a variety of autoimmune disorders.	glycolsylphosphatidylinositol	50-79	CD59 molecule (CD59 blood group)	Homo sapiens	127-131
19169834-4	2009	Overall mean bias [95% confidence interval (CI)] of rate of uptake was 17.9 [7.3 to 28.5] ml min(-1) for oxygen, 0.04 [-0.42 to 0.50] ml min(-1) for sevoflurane, 10.9 [-16.1 to 37.8] for CO(2), and 8.8 [-14.8 to 32.4] ml min(-1) for nitrous oxide where present.	Oxygen	105-111	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
19141813-4	2009	Over the first 1.5 yr of operation, mean influent NO3-N of 4.8 mg L(-1) was attenuated to 1.04 mg L(-1) at a mean reactor flow rate of 24 L min(-1).	no3-n	50-55	CD59 molecule (CD59 blood group)	Homo sapiens	140-146
19479577-5	2009	RESULTS: Peak oxygen uptake was 671 +/- 192 mL min(-1) (mean + standard deviation), peak HR 90 +/- 12 beats min(-1), net peak power 8.4 +/- 3.3 W and peak minute ventilation 23.6 +/- 7.5 L min(-1).	Oxygen	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	47-53
19027976-7	2009	When the patients were stratified by the estimated glomerular filtration rate, serum indoxyl sulfate was elevated in groups with estimated glomerular filtration rates of 60-89 mL/min/1.73 m(2) and below.	Indican	85-100	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
18990420-4	2009	For initial solution pH>6.5, the phosphorus removal through struvite precipitation could be improved by increasing the airflow rate up to 25 L min(-1), or by increasing the initial pH for higher airflow rates.	Phosphorus	36-46	CD59 molecule (CD59 blood group)	Homo sapiens	146-152
19713609-2	2009	In medicine and biotechnology the permeability is given usually as the amount of water (ml x cm(-2) x min(-1)) permeating per area and time unit through the material.	Water	81-86	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
19108496-10	2008	Thus, we started to administer dopamine at an infusion rate of 10 microg x kg(-1) x min(-1) which increased blood pressure effectively, but electrocardiogram showed second-degree atrioventricular block (Mobitz type II).	Dopamine	31-39	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
19377254-8	2009	Univariate analysis demonstrated that nephrotic syndrome, acute nephritic syndrome and a creatinine clearance less than 30 mL/min/1.73 m2 were all associated with a significantly increased risk of developing grades IV and/or V lesions.	Creatinine	89-99	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
19921354-4	2009	Landiolol was dissolved in 20 ml of saline and administered as an infusion at the rate of 0.125 mg kg(-1) min(-1) for 1 min and then decreased to 0.04 mg kg(-1) min(-1) until extubation.	landiolol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	106-123
19396321-9	2009	ROC curves showed that the most accurate levels to predict digoxin over dosage were MDRD<56 ml/min/1.73 m(2) in men and MDRD<52 ml/min/1.73 m(2) in women.	Digoxin	59-66	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
19396321-9	2009	ROC curves showed that the most accurate levels to predict digoxin over dosage were MDRD<56 ml/min/1.73 m(2) in men and MDRD<52 ml/min/1.73 m(2) in women.	Digoxin	59-66	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
19404395-6	2009	Importantly, our fluorescence-topographic NSOM imaging demonstrated that GM1/CD59 raft markers distributed and re-distributed at mounds but not depressions of T-cell membrane fluctuations.	G(M1) Ganglioside	73-76	CD59 molecule (CD59 blood group)	Homo sapiens	77-81
19088803-5	2008	Ten patients were given 50 microg x min-1 enalaprilat in an intracoronary infusion between the balloon inflations, whereas the others received an infusion of saline.	Enalaprilat	42-53	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
19108496-11	2008	We started rapid infusion of a plasma substitute, and gradually decreased the infusion rate of dopamine to 4 microg x kg(-1) x min(-1).	Dopamine	95-103	CD59 molecule (CD59 blood group)	Homo sapiens	127-133
18949800-1	2008	BACKGROUND: Despite their controversial effect, "renal" doses of dopamine (3-5 microg kg(-1) min(-1)) are often used in intensive care units to preserve renal function and to improve final outcome.	Dopamine	65-73	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
19271511-4	2008	After centrifuging for 10 min at 12 000 r x min(-1), the excess nanogold-labeled anti-C3 in the upper solutions was obtained, and was used to catalyze the colored particle reaction between HAuCl4 and NH2 OH x HCl to produce gold particles with bigger size.	gold tetrachloride, acid	189-195	CD59 molecule (CD59 blood group)	Homo sapiens	44-50
19271511-4	2008	After centrifuging for 10 min at 12 000 r x min(-1), the excess nanogold-labeled anti-C3 in the upper solutions was obtained, and was used to catalyze the colored particle reaction between HAuCl4 and NH2 OH x HCl to produce gold particles with bigger size.	nh2 oh x hcl	200-212	CD59 molecule (CD59 blood group)	Homo sapiens	44-50
18789444-6	2008	The combined macro-scale/micro-scale approach indicated that 0.3 ml min(-1), which subjected 95% of the cells to less than 6.3 mPa shear, would maintain the oxygen supply throughout the scaffold above anoxic levels (>1%), with 99.5% of the scaffold supplied with 8-2% O(2).	Oxygen	157-163	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
18942041-4	2008	In human liver microsomes, morphine 3-glucuronide and morphine 6-glucuronide formation had V(max) estimates of 6.2 +/- 0.07 and 0.75 +/- 0.01 (nmole min(-1) mg(-1) protein) and K(m) estimates of 1080 +/- 37 and 665 +/- 55 (microM), respectively.	morphine-3-glucuronide	27-49	CD59 molecule (CD59 blood group)	Homo sapiens	149-155
18942041-4	2008	In human liver microsomes, morphine 3-glucuronide and morphine 6-glucuronide formation had V(max) estimates of 6.2 +/- 0.07 and 0.75 +/- 0.01 (nmole min(-1) mg(-1) protein) and K(m) estimates of 1080 +/- 37 and 665 +/- 55 (microM), respectively.	morphine-6-glucuronide	54-76	CD59 molecule (CD59 blood group)	Homo sapiens	149-155
18923574-8	2008	Validated THR ranges for sedentary overweight and obese pregnant women are 102-124 beats.min-1 (20-29 years of age) and 101-120 beats.min-1 (30-39 years of age), representing an exercise intensity of 20%-39%VO2 reserve as recommended by the American College of Sports Medicine for previously sedentary pregnant women.	Threonine	10-13	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
18703581-5	2008	Comparison of the doses of nucleotides and adenosine required for a similar increase in LBF from approximately 0.5 l min(-1) at baseline to approximately 3.5 l min(-1) (without altering MAP but increasing Q significantly) revealed the following rank order of vasoactive potency: ATP (100) = UTP (100) >> adenosine (5.8) > ADP (2.7) > AMP (1.7).	Adenosine	43-52	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
18703581-5	2008	Comparison of the doses of nucleotides and adenosine required for a similar increase in LBF from approximately 0.5 l min(-1) at baseline to approximately 3.5 l min(-1) (without altering MAP but increasing Q significantly) revealed the following rank order of vasoactive potency: ATP (100) = UTP (100) >> adenosine (5.8) > ADP (2.7) > AMP (1.7).	Adenosine	43-52	CD59 molecule (CD59 blood group)	Homo sapiens	160-166
18703581-7	2008	Combined infusion of the vasodilatory compounds and the sympathetic vasoconstrictor drug tyramine increased plasma noradrenaline in all hyperaemic conditions, but only caused leg and systemic vasoconstriction and augmented O(2) extraction during adenosine, AMP and ADP infusion (LBF from 3.2 +/- 0.3 to 1.8 +/- 0.2 l min(-1); 3.7 +/- 0.4 to 1.7 +/- 0.2 l min(-1) and 3.3 +/- 0.4 to 2.4 +/- 0.3 l min(-1), respectively, P < 0.05).	Tyramine	89-97	CD59 molecule (CD59 blood group)	Homo sapiens	317-323
18703581-7	2008	Combined infusion of the vasodilatory compounds and the sympathetic vasoconstrictor drug tyramine increased plasma noradrenaline in all hyperaemic conditions, but only caused leg and systemic vasoconstriction and augmented O(2) extraction during adenosine, AMP and ADP infusion (LBF from 3.2 +/- 0.3 to 1.8 +/- 0.2 l min(-1); 3.7 +/- 0.4 to 1.7 +/- 0.2 l min(-1) and 3.3 +/- 0.4 to 2.4 +/- 0.3 l min(-1), respectively, P < 0.05).	Tyramine	89-97	CD59 molecule (CD59 blood group)	Homo sapiens	355-361
18703581-7	2008	Combined infusion of the vasodilatory compounds and the sympathetic vasoconstrictor drug tyramine increased plasma noradrenaline in all hyperaemic conditions, but only caused leg and systemic vasoconstriction and augmented O(2) extraction during adenosine, AMP and ADP infusion (LBF from 3.2 +/- 0.3 to 1.8 +/- 0.2 l min(-1); 3.7 +/- 0.4 to 1.7 +/- 0.2 l min(-1) and 3.3 +/- 0.4 to 2.4 +/- 0.3 l min(-1), respectively, P < 0.05).	Tyramine	89-97	CD59 molecule (CD59 blood group)	Homo sapiens	355-361
18923574-8	2008	Validated THR ranges for sedentary overweight and obese pregnant women are 102-124 beats.min-1 (20-29 years of age) and 101-120 beats.min-1 (30-39 years of age), representing an exercise intensity of 20%-39%VO2 reserve as recommended by the American College of Sports Medicine for previously sedentary pregnant women.	Threonine	10-13	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
18827360-6	2008	min(-1) in 0.1 M hydrochloric acid (HCl) and pH 6.8 phosphate buffer.	Hydrochloric Acid	17-34	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
18827360-6	2008	min(-1) in 0.1 M hydrochloric acid (HCl) and pH 6.8 phosphate buffer.	Hydrochloric Acid	36-39	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
18827360-6	2008	min(-1) in 0.1 M hydrochloric acid (HCl) and pH 6.8 phosphate buffer.	Phosphates	52-61	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
18650100-5	2008	Examination of the energy landscapes obtained for combinations of these parameters showed that a low internal energy region (<or=1.0 eV) was present at nitrogen flow rates between 2 and 4 L min(-1) and capillary temperatures up to 250 degrees C using ESI (9% of all parameter combinations tested).	Nitrogen	155-163	CD59 molecule (CD59 blood group)	Homo sapiens	193-199
18991938-5	2008	The desulfurization rate of thiophene in n-octane was 65.2% under photoirradiation for 5 h under the conditions of air flow at 150 mL min(-1), and V(n-octane):V(acetonitrile) = 1:1.	Thiophenes	28-37	CD59 molecule (CD59 blood group)	Homo sapiens	134-140
18991938-5	2008	The desulfurization rate of thiophene in n-octane was 65.2% under photoirradiation for 5 h under the conditions of air flow at 150 mL min(-1), and V(n-octane):V(acetonitrile) = 1:1.	octane	41-49	CD59 molecule (CD59 blood group)	Homo sapiens	134-140
19123377-5	2008	The experimental results show that the emission intensity increased with discharge current from 1 to 6 mA and argon flow rate from 100 to 700 mL x min(-1).	Argon	110-115	CD59 molecule (CD59 blood group)	Homo sapiens	147-153
18975538-5	2008	Remifentanil (0.1-0.25 microg x kg(-1) x min(-1)) maintained the patients" spontaneous ventilation and increased their tolerance to the pain and discomfort caused by insertion of the lightwand.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	41-47
19083472-5	2008	Phenylalanine balance (nmol x min(-1) kg lean leg mass(-1)) during the 3.5 hours after the bolus ingestion improved in the WY (-216 +/- 14 vs -105 +/- 19; P < .05) but not in the EAA (-203 +/- 21 vs -172 +/- 38; P > .05) or NEAA groups (-203 +/- 19 vs -204 +/- 21; P > .05).	Phenylalanine	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	30-36
18676075-11	2008	In patients with eGFR of 90 mL/min/1.73 m(2) or greater, the pravastatin arm tended to have a higher eGFR.	Pravastatin	61-72	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
18807903-7	2008	Heart rate was controlled around 90 beats x min(-1) using landiolol during surgery.	landiolol	58-67	CD59 molecule (CD59 blood group)	Homo sapiens	44-50
18768048-7	2008	The patients in the dexamethasone plus propofol group received 1 mg x kg(-1) propofol before intubation and continuously after intubation at a rate of 20 microg x kg(-1) x min(-1) until the surgery was completed.	Dexamethasone	20-33	CD59 molecule (CD59 blood group)	Homo sapiens	172-178
18307573-7	2008	RESULTS: The average serum creatinine clearance in our group was 132.84 ml/min/1.73 m(2) (46.8-510).	Creatinine	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
18507656-5	2008	RESULTS: Fingolimod administration alone yielded a heart rate nadir of 51 +/- 5 beats min(-1) at a median 4 h postdose with heart rate remaining depressed at 51-64 beats min(-1) over the rest of the day.	Fingolimod Hydrochloride	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
18507656-6	2008	Concurrent administration of fingolimod and atropine yielded a nadir of 66 +/- 6 beats min(-1) resulting in an atropine: placebo ratio (90% confidence interval) of 1.30 (1.22, 1.36).	Fingolimod Hydrochloride	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
18507656-6	2008	Concurrent administration of fingolimod and atropine yielded a nadir of 66 +/- 6 beats min(-1) resulting in an atropine: placebo ratio (90% confidence interval) of 1.30 (1.22, 1.36).	Atropine	44-52	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
18507656-6	2008	Concurrent administration of fingolimod and atropine yielded a nadir of 66 +/- 6 beats min(-1) resulting in an atropine: placebo ratio (90% confidence interval) of 1.30 (1.22, 1.36).	Atropine	111-119	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
18507656-7	2008	When atropine was administered at the time of the nadir, it was able to reverse the negative chronotropic effect of fingolimod from a heart rate of 56 +/- 9 beats min(-1) (placebo) to 64 +/- 8 beats min(-1) (atropine) resulting in an atropine: placebo ratio of 1.15 (1.04, 1.26).	Atropine	5-13	CD59 molecule (CD59 blood group)	Homo sapiens	163-169
18507656-7	2008	When atropine was administered at the time of the nadir, it was able to reverse the negative chronotropic effect of fingolimod from a heart rate of 56 +/- 9 beats min(-1) (placebo) to 64 +/- 8 beats min(-1) (atropine) resulting in an atropine: placebo ratio of 1.15 (1.04, 1.26).	Atropine	5-13	CD59 molecule (CD59 blood group)	Homo sapiens	199-205
18507656-7	2008	When atropine was administered at the time of the nadir, it was able to reverse the negative chronotropic effect of fingolimod from a heart rate of 56 +/- 9 beats min(-1) (placebo) to 64 +/- 8 beats min(-1) (atropine) resulting in an atropine: placebo ratio of 1.15 (1.04, 1.26).	Fingolimod Hydrochloride	116-126	CD59 molecule (CD59 blood group)	Homo sapiens	163-169
18507656-7	2008	When atropine was administered at the time of the nadir, it was able to reverse the negative chronotropic effect of fingolimod from a heart rate of 56 +/- 9 beats min(-1) (placebo) to 64 +/- 8 beats min(-1) (atropine) resulting in an atropine: placebo ratio of 1.15 (1.04, 1.26).	Fingolimod Hydrochloride	116-126	CD59 molecule (CD59 blood group)	Homo sapiens	199-205
18539604-4	2008	propofol at an average rate of 10 mg min(-1).	Propofol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	37-43
18589149-6	2008	The estimated glomerular filtration rate (eGFR) at 6 months was higher in the steroid-free group (74.8 vs 55.7 mL/min/1.73 m2 in the steroid-based group, P = .001), with fewer occurrences of a 25% decline in eGFR (33.3% among the steroid-free group vs 61.7% among steroid-based group, P = .019), despite similar average tacrolimus exposure (11.7 +/- 3.7 vs 12.2 +/- 2.7 ng/dL, P = .478).	Steroids	78-85	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
18518865-4	2008	The mean (SD) fractional end-tidal oxygen at the end of 3 min was 0.86 (0.07) for 5 l.min(-1), 0.92 (0.05) for 10 l.min(-1)and 0.90 (0.09) for 15 l.min(-1) (p < 0.001).	Oxygen	35-41	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
18518865-4	2008	The mean (SD) fractional end-tidal oxygen at the end of 3 min was 0.86 (0.07) for 5 l.min(-1), 0.92 (0.05) for 10 l.min(-1)and 0.90 (0.09) for 15 l.min(-1) (p < 0.001).	Oxygen	35-41	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
18518865-4	2008	The mean (SD) fractional end-tidal oxygen at the end of 3 min was 0.86 (0.07) for 5 l.min(-1), 0.92 (0.05) for 10 l.min(-1)and 0.90 (0.09) for 15 l.min(-1) (p < 0.001).	Oxygen	35-41	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
18518865-6	2008	Oxygen flow rates of 10 l.min(-1) or above provide optimal pre-oxygenation using a circle system in term parturients.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	26-32
18710014-7	2008	Although we gave her O2 6 l x min(-1) after extubation, she showed low oxygen saturation (90%), thus we started bag-mask ventilation.	Oxygen	21-23	CD59 molecule (CD59 blood group)	Homo sapiens	30-36
18573839-6	2008	RESULTS: Wearing FES lead to a significant improvement in walking speed (0.49 ms(-1) and 0.43 ms(-1) with and without their FES respectively; P<0.001) and a significant reduction in the physiological cost of gait (0.41 mL min(-1) kg(-1) m(-1) and 0.46 mL min(-1) kg(-1) m(-1) with and without FES respectively; P=0.017) in pwMS.	fes	17-20	CD59 molecule (CD59 blood group)	Homo sapiens	225-231
18573839-6	2008	RESULTS: Wearing FES lead to a significant improvement in walking speed (0.49 ms(-1) and 0.43 ms(-1) with and without their FES respectively; P<0.001) and a significant reduction in the physiological cost of gait (0.41 mL min(-1) kg(-1) m(-1) and 0.46 mL min(-1) kg(-1) m(-1) with and without FES respectively; P=0.017) in pwMS.	fes	17-20	CD59 molecule (CD59 blood group)	Homo sapiens	258-264
18585335-5	2008	At a flow of 0.3 mL min(-1) the separation of both Cr species was possible within 8 min.	Chromium	51-53	CD59 molecule (CD59 blood group)	Homo sapiens	20-26
19040016-5	2008	The oxygen consumption at the anaerobic threshold (VO2AT) 3 months later of the exercise group was [(12.6 +/- 2.9) ml x min(-1) x kg(1)], significantly greater and that before the exercise [(10.5 x 2.9) ml x min x kg(-1), P = 0.000].	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	120-126
19040016-6	2008	The peak oxygen uptake (VO2 pea) 3 months of the exercise group was (20 +/- 4) ml x min(-1) x kg(-1), signficantly greater then that before exercise [(14 +/- 4) ml x min(-1) x kg(-1), P = 0.000].	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
17913559-9	2008	The average dynamic O2 cost for protocol C (6.53 (+/-0.46) ml min(-1)W(-1)) was lower than that of protocol A (10.02 (+/-1.16) ml min(-1) W(-1)) and protocol B (10.03 (+/-0.91) ml min(-1) W(-1)).	Oxygen	20-22	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
18480669-8	2008	0.2 mg NTG provoked a long-lasting and significant decrease in coronary flow volume (from 140.2+/-34.2 to 91.2+/-21.8 ml/min, P<0.002), a marked increase in coronary vascular resistance (from 0.62 to 0.92 mmHG x ml/min(-1), P<0.002) and an inadequate increase in coronary flow volume under cardiac pacing.	Nitroglycerin	7-10	CD59 molecule (CD59 blood group)	Homo sapiens	218-224
19031739-7	2008	2) Phosphatase assay showed a decrease in PP2A phosphatase activity [(534 +/- 43) pmol x min(-1) x microg protein(-1)] in NB4 after ATRA treatment, accompanied with that activity [(959 +/- 83) pmol x min(-1) x microg protein(-1)] in untreated NB4 cells.	Tretinoin	132-136	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
19031739-7	2008	2) Phosphatase assay showed a decrease in PP2A phosphatase activity [(534 +/- 43) pmol x min(-1) x microg protein(-1)] in NB4 after ATRA treatment, accompanied with that activity [(959 +/- 83) pmol x min(-1) x microg protein(-1)] in untreated NB4 cells.	Tretinoin	132-136	CD59 molecule (CD59 blood group)	Homo sapiens	200-206
19031739-9	2008	When OKA + ATRA was incubated with MR2, PP2A in the cells was significantly decreased [(229 +/- 23) pmol x min(-1) x microg protein(-1)].	oka + atra	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
18294315-5	2008	RESULTS: The sweat production rate of the half of the forehead treated with topical glycopyrrolate was significantly reduced to 37.6+/-2.8 mg min(-1) (mean+/-SEM) compared with 102.2+/-5.5 mg min(-1) at the placebo-treated half of the forehead (P<0.001).	Glycopyrrolate	84-98	CD59 molecule (CD59 blood group)	Homo sapiens	142-148
18294315-5	2008	RESULTS: The sweat production rate of the half of the forehead treated with topical glycopyrrolate was significantly reduced to 37.6+/-2.8 mg min(-1) (mean+/-SEM) compared with 102.2+/-5.5 mg min(-1) at the placebo-treated half of the forehead (P<0.001).	Glycopyrrolate	84-98	CD59 molecule (CD59 blood group)	Homo sapiens	192-198
18343103-3	2008	The purified enzyme is highly specific to cholesterol sulphate (specific activity 2126.60+/-940.90 nmol min(-1) mg protein(-1)) and acts optimally at pH 3.4.	cholesteryl sulfate	42-62	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
18438213-6	2008	Oxygen consumption was significantly lower carrying the double-strap golf bag (L x min(-1), p = 0.0004; ml x kg(-1) x min(-1), p < 0.0003), as were heart rate (p = 0.0013) and rate of perceived exertion (p < 0.005) During the double strap trial, the perceived comfort was higher (p < 0.005).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	83-89
18438213-6	2008	Oxygen consumption was significantly lower carrying the double-strap golf bag (L x min(-1), p = 0.0004; ml x kg(-1) x min(-1), p < 0.0003), as were heart rate (p = 0.0013) and rate of perceived exertion (p < 0.005) During the double strap trial, the perceived comfort was higher (p < 0.005).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
18237814-4	2008	Kinetic experiments indicated that in PBS, the rate constants of lactone hydrolysis and carboxylate lactonization were 3.10 (+/-0.33)x10(-3) min(-1) and 1.36 (+/-0.04)x10(-3) min(-1), respectively.	Lead	38-41	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
18237814-4	2008	Kinetic experiments indicated that in PBS, the rate constants of lactone hydrolysis and carboxylate lactonization were 3.10 (+/-0.33)x10(-3) min(-1) and 1.36 (+/-0.04)x10(-3) min(-1), respectively.	Lead	38-41	CD59 molecule (CD59 blood group)	Homo sapiens	175-181
18237814-4	2008	Kinetic experiments indicated that in PBS, the rate constants of lactone hydrolysis and carboxylate lactonization were 3.10 (+/-0.33)x10(-3) min(-1) and 1.36 (+/-0.04)x10(-3) min(-1), respectively.	Lactones	65-72	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
18237814-4	2008	Kinetic experiments indicated that in PBS, the rate constants of lactone hydrolysis and carboxylate lactonization were 3.10 (+/-0.33)x10(-3) min(-1) and 1.36 (+/-0.04)x10(-3) min(-1), respectively.	Lactones	65-72	CD59 molecule (CD59 blood group)	Homo sapiens	175-181
18405497-7	2008	RESULTS: There was an increase in VO2 peak on L-carnitine group from 16.3 (2.8) mL x Kg(-1) x min(-1) to 19.5 (3.3) mL x Kg(-1) x min(-1), and the same was seen in the placebo group (increase in VO2 peak from 14.8 (3.8) mL x Kg(-1) x min(-1) to 18.9 (4.8) mL x Kg(-1) x min(-1)).	Carnitine	46-57	CD59 molecule (CD59 blood group)	Homo sapiens	94-100
18405497-7	2008	RESULTS: There was an increase in VO2 peak on L-carnitine group from 16.3 (2.8) mL x Kg(-1) x min(-1) to 19.5 (3.3) mL x Kg(-1) x min(-1), and the same was seen in the placebo group (increase in VO2 peak from 14.8 (3.8) mL x Kg(-1) x min(-1) to 18.9 (4.8) mL x Kg(-1) x min(-1)).	Carnitine	46-57	CD59 molecule (CD59 blood group)	Homo sapiens	130-136
18405497-7	2008	RESULTS: There was an increase in VO2 peak on L-carnitine group from 16.3 (2.8) mL x Kg(-1) x min(-1) to 19.5 (3.3) mL x Kg(-1) x min(-1), and the same was seen in the placebo group (increase in VO2 peak from 14.8 (3.8) mL x Kg(-1) x min(-1) to 18.9 (4.8) mL x Kg(-1) x min(-1)).	Carnitine	46-57	CD59 molecule (CD59 blood group)	Homo sapiens	130-136
18405497-7	2008	RESULTS: There was an increase in VO2 peak on L-carnitine group from 16.3 (2.8) mL x Kg(-1) x min(-1) to 19.5 (3.3) mL x Kg(-1) x min(-1), and the same was seen in the placebo group (increase in VO2 peak from 14.8 (3.8) mL x Kg(-1) x min(-1) to 18.9 (4.8) mL x Kg(-1) x min(-1)).	Carnitine	46-57	CD59 molecule (CD59 blood group)	Homo sapiens	130-136
18270231-9	2008	The EC(50 Propofol) and the k(e0 Propofol) were 5.2 (2.7) microg ml(-1) and 0.60 (0.45) min(-1), respectively.	Propofol	10-18	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
18270231-9	2008	The EC(50 Propofol) and the k(e0 Propofol) were 5.2 (2.7) microg ml(-1) and 0.60 (0.45) min(-1), respectively.	Propofol	33-41	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
18270231-10	2008	The k(e0 Propofol) decreased from approximately 0.91 min(-1) at 1 yr to 0.15 min(-1) at 16 yr.	Propofol	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	53-59
18270231-10	2008	The k(e0 Propofol) decreased from approximately 0.91 min(-1) at 1 yr to 0.15 min(-1) at 16 yr.	Propofol	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	77-83
18200040-6	2008	OS was significantly shorter in dexamethasone patients with CrCl < or =50 vs >50 ml min(-1) (P=0.003), indicating that bortezomib is more effective than dexamethasone in overcoming the detrimental effect of renal impairment.	Dexamethasone	32-45	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
18200040-6	2008	OS was significantly shorter in dexamethasone patients with CrCl < or =50 vs >50 ml min(-1) (P=0.003), indicating that bortezomib is more effective than dexamethasone in overcoming the detrimental effect of renal impairment.	Bortezomib	125-135	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
18200040-8	2008	With dexamethasone, grade 3/4 adverse events (AEs), serious AEs and discontinuations for AEs were significantly elevated in patients with CrCl < or =50 vs >50 ml min(-1).	Dexamethasone	5-18	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
27408108-5	2008	The mean measured creatinine clearance was 87.15 ml/min/1.73m(2), SD +- 20.5 (range 56.9-137 ml/min/1.73m(2)).	Creatinine	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
27408108-6	2008	In 25 (50%) patients, one hour urinary creatinine clearance was <80 ml/min/1.73m(2) and in two (4%) patients, the creatinine clearance was <60 ml/min/1.73m(2).	Creatinine	39-49	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
27408108-8	2008	The differences between the predictive equations and creatinine clearance, as illustrated by the +-95% confidence interval in the Bland-Altman graphs was very significant [Cockcroft- Gault = -40.3 to 17.7 ml/min/ 1.73m(2), Modification of Diet in Renal Disease equation = -46.2 to 30.6 ml/min/1.73m(2) and the simplified Modification of Diet in Renal Disease equation = -72.8 to 24.8 ml/min/1.73m(2)].	Creatinine	53-63	CD59 molecule (CD59 blood group)	Homo sapiens	289-294
27408108-8	2008	The differences between the predictive equations and creatinine clearance, as illustrated by the +-95% confidence interval in the Bland-Altman graphs was very significant [Cockcroft- Gault = -40.3 to 17.7 ml/min/ 1.73m(2), Modification of Diet in Renal Disease equation = -46.2 to 30.6 ml/min/1.73m(2) and the simplified Modification of Diet in Renal Disease equation = -72.8 to 24.8 ml/min/1.73m(2)].	Creatinine	53-63	CD59 molecule (CD59 blood group)	Homo sapiens	387-392
18428041-0	2008	Patching of ganglioside(M1) in human erythrocytes - distribution of CD47 and CD59 in patched and curved membrane.	Gangliosides	12-23	CD59 molecule (CD59 blood group)	Homo sapiens	77-81
18428041-0	2008	Patching of ganglioside(M1) in human erythrocytes - distribution of CD47 and CD59 in patched and curved membrane.	m1	24-26	CD59 molecule (CD59 blood group)	Homo sapiens	77-81
18428041-3	2008	We have studied by fluorescence microscopy cross-linking of ganglioside GM1 in the human erythrocyte membrane, and how membrane proteins CD47 and CD59 distribute in GM1 patched discoid cells and calcium-induced echinocytic cells.	G(M1) Ganglioside	165-168	CD59 molecule (CD59 blood group)	Homo sapiens	146-150
18428041-3	2008	We have studied by fluorescence microscopy cross-linking of ganglioside GM1 in the human erythrocyte membrane, and how membrane proteins CD47 and CD59 distribute in GM1 patched discoid cells and calcium-induced echinocytic cells.	Calcium	195-202	CD59 molecule (CD59 blood group)	Homo sapiens	146-150
18428041-12	2008	However, CD59 showed a low degree of co-localization with GM1 and frequently accumulated in different spiculae than GM1.	G(M1) Ganglioside	58-61	CD59 molecule (CD59 blood group)	Homo sapiens	9-13
18428041-15	2008	Glycosyl phosphatidylinositol-anchored CD59 was identified as a mobile "echinophilic" but "raftophobic(GM1)" protein.	Glycosylphosphatidylinositols	0-29	CD59 molecule (CD59 blood group)	Homo sapiens	39-43
18328313-2	2008	Different mixtures of gases (He and H2) were tested using HCl conditions and a He flow rate of 4 mL min(-1) was found to be suitable for the removal of the poly-atomic spectral interference [40Ar35Cl]+.	Helium	29-31	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
18328313-2	2008	Different mixtures of gases (He and H2) were tested using HCl conditions and a He flow rate of 4 mL min(-1) was found to be suitable for the removal of the poly-atomic spectral interference [40Ar35Cl]+.	Hydrogen	36-38	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
18328313-2	2008	Different mixtures of gases (He and H2) were tested using HCl conditions and a He flow rate of 4 mL min(-1) was found to be suitable for the removal of the poly-atomic spectral interference [40Ar35Cl]+.	Helium	79-81	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
18291138-7	2008	Trantinterol enantiomers were resolved (R(s)=2.73) within 14 min using n-hexane-ethanol-TEA (98:2:0.1, v/v/v) as mobile phase with a flow rate of 0.8 mL min(-1) at 30 degrees C. The optimized method was validated for linearity, precision, accuracy and stability in solution and proved to be robust.	trantinterol	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	153-159
18299748-7	2008	However, it was still possible to relate the 1H NMR signal obtained at a flow rate of 60 mL min(-1) to the composition of the reactor contents.	Hydrogen	45-47	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
19039422-6	2008	The multiple regression lines had described two models to estimate the maximum oxygen consumption with the following average values: model 1 =48 ,46 +/-11,41 and model 2=46,83+/-11.11 ml/kg.min -1 .	Oxygen	79-85	CD59 molecule (CD59 blood group)	Homo sapiens	190-196
18264130-5	2008	Forty minutes after the last reperfusion period, this procedure was repeated during intra-arterial infusion of dipyridamole (7.4 nmol min(-1) per 100 ml forearm).	Dipyridamole	111-123	CD59 molecule (CD59 blood group)	Homo sapiens	134-140
18264130-6	2008	At least 2 weeks later, this whole procedure was repeated, but now in the presence of caffeine (90 microg min(-1) per 100 ml volume).	Caffeine	86-94	CD59 molecule (CD59 blood group)	Homo sapiens	106-112
18264130-8	2008	After infusion of dipyridamole into the brachial artery, these numbers were significantly increased to 7.7+/-0.8, 12.5+/-1.5 and 41.6+/-3.1 ml min(-1) per 100 ml.	Dipyridamole	18-30	CD59 molecule (CD59 blood group)	Homo sapiens	143-149
18264130-9	2008	This response was abolished by the concomitant infusion of caffeine (6.6+/-0.5, 10.2+/-0.6, 35.1+/-2.2 (caffeine) versus 7.4+/-0.4, 10.5+/-0.6, 33.7+/-2.2 ml min(-1)per 100 ml (caffeine/dipyridamole)).	Caffeine	59-67	CD59 molecule (CD59 blood group)	Homo sapiens	158-164
19039422-8	2008	The average results of the maximum oxygen consumption estimated for Group 2 model 1=48 ,14 +/-10,74 ml/kg.min -1 and model 2 =46,59+/-10,36 ml/kg.min -1 were not significantly different from the values observed in the effort test.	Oxygen	35-41	CD59 molecule (CD59 blood group)	Homo sapiens	106-112
18048452-9	2008	The change (Delta) in FBF during 10% hypoxic exercise was greater with phentolamine (Delta306 +/- 43 ml min(-1)) vs. saline (Delta169 +/- 30 ml min(-1)) or combined phentolamine/propranolol (Delta213 +/- 25 ml min(-1); P < 0.05 for both).	Phentolamine	71-83	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
18048452-9	2008	The change (Delta) in FBF during 10% hypoxic exercise was greater with phentolamine (Delta306 +/- 43 ml min(-1)) vs. saline (Delta169 +/- 30 ml min(-1)) or combined phentolamine/propranolol (Delta213 +/- 25 ml min(-1); P < 0.05 for both).	Phentolamine	71-83	CD59 molecule (CD59 blood group)	Homo sapiens	144-150
18048452-9	2008	The change (Delta) in FBF during 10% hypoxic exercise was greater with phentolamine (Delta306 +/- 43 ml min(-1)) vs. saline (Delta169 +/- 30 ml min(-1)) or combined phentolamine/propranolol (Delta213 +/- 25 ml min(-1); P < 0.05 for both).	Phentolamine	71-83	CD59 molecule (CD59 blood group)	Homo sapiens	144-150
18048452-10	2008	During 20% hypoxic exercise, DeltaFBF was greater with phentalomine (Delta466 +/- 57 ml min(-1); P < 0.05) vs. saline (Delta346 +/- 40 ml min(-1)) but was similar to combined phentolamine/propranolol (Delta450 +/- 43 ml min(-1)).	deltafbf	29-37	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
18048452-10	2008	During 20% hypoxic exercise, DeltaFBF was greater with phentalomine (Delta466 +/- 57 ml min(-1); P < 0.05) vs. saline (Delta346 +/- 40 ml min(-1)) but was similar to combined phentolamine/propranolol (Delta450 +/- 43 ml min(-1)).	phentalomine	55-67	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
18048452-10	2008	During 20% hypoxic exercise, DeltaFBF was greater with phentalomine (Delta466 +/- 57 ml min(-1); P < 0.05) vs. saline (Delta346 +/- 40 ml min(-1)) but was similar to combined phentolamine/propranolol (Delta450 +/- 43 ml min(-1)).	phentalomine	55-67	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
18048452-10	2008	During 20% hypoxic exercise, DeltaFBF was greater with phentalomine (Delta466 +/- 57 ml min(-1); P < 0.05) vs. saline (Delta346 +/- 40 ml min(-1)) but was similar to combined phentolamine/propranolol (Delta450 +/- 43 ml min(-1)).	phentalomine	55-67	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
18277575-2	2008	The premature labor had been inhibited for 2 weeks with ritodrine (100 microg min(-1) continuous infusion).	Ritodrine	56-65	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
18360037-8	2008	When CKD stage 3 was divided at eGFR 45 mL/min/1.73 m2, the baPWV of stage 3b (eGFR 30 to 44) was significantly higher than that of stage 3a (eGFR 45 to 59) independent of traditional risk factors, suggesting that an eGFR of 45 mL/min/1.73 m2 may be a critical cut off value to predict arterial stiffness in CKD.	bapwv	60-65	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
18360037-8	2008	When CKD stage 3 was divided at eGFR 45 mL/min/1.73 m2, the baPWV of stage 3b (eGFR 30 to 44) was significantly higher than that of stage 3a (eGFR 45 to 59) independent of traditional risk factors, suggesting that an eGFR of 45 mL/min/1.73 m2 may be a critical cut off value to predict arterial stiffness in CKD.	bapwv	60-65	CD59 molecule (CD59 blood group)	Homo sapiens	231-236
18376155-12	2008	Oxygen requirements for desired FiO2 and VE resulted in a mean oxygen usage of 3.24 L/min +/- 1.87 L/min (range, 1.6-10.2 L/min).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	86-95
18507353-2	2008	The flow rate was 0.5 mL min(-1), the detection wavelength was 251 nm, and the column temperature was 40 degrees C. The calibration curve was linear in the range of 18 - 1450 ng of aristolochic acid A with correlation coefficient of 0.	aristolochic acid I	181-200	CD59 molecule (CD59 blood group)	Homo sapiens	25-31
18086073-6	2008	Penetration of sodium chloride particles varied from 1.9 to 18% at 15 l x min(-1) for the six filters.	Sodium Chloride	15-30	CD59 molecule (CD59 blood group)	Homo sapiens	74-80
18024954-7	2008	The bias between the two methods (CO(EV)-CO(F)) was 0.01 litre min(-1) and the limits of agreement, defined as the bias (2 SD), were -0.47 and +0.45 litre min(-1).	co(ev)	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
18997379-4	2008	On the basis of this fundamental result, the total microchannel length required for the reaction of 2,3-diaminonaphthalene (DAN) and NO2- at a flow rate of 2 microL min(-1) was calculated, and the obtained value ( approximately 100 mm) showed very good agreement with our previous microchip research.	2,3-diaminonaphthalene	100-122	CD59 molecule (CD59 blood group)	Homo sapiens	165-171
18997379-4	2008	On the basis of this fundamental result, the total microchannel length required for the reaction of 2,3-diaminonaphthalene (DAN) and NO2- at a flow rate of 2 microL min(-1) was calculated, and the obtained value ( approximately 100 mm) showed very good agreement with our previous microchip research.	2,3-diaminonaphthalene	124-127	CD59 molecule (CD59 blood group)	Homo sapiens	165-171
18997379-4	2008	On the basis of this fundamental result, the total microchannel length required for the reaction of 2,3-diaminonaphthalene (DAN) and NO2- at a flow rate of 2 microL min(-1) was calculated, and the obtained value ( approximately 100 mm) showed very good agreement with our previous microchip research.	Nitrogen Dioxide	133-136	CD59 molecule (CD59 blood group)	Homo sapiens	165-171
18024954-7	2008	The bias between the two methods (CO(EV)-CO(F)) was 0.01 litre min(-1) and the limits of agreement, defined as the bias (2 SD), were -0.47 and +0.45 litre min(-1).	COF protocol	41-46	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
18090356-13	2008	"At-risk" tissue defined by the physiologic region of interest, however, showed a universal increase in cerebral metabolic rate of oxygen from a median (interquartile range) of 23 (22-25) micromol x 100 mL(-1) x min(-1) to 30 (28-36) micromol x 100 mL(-1) x min(-1) (p < .01).	Oxygen	131-137	CD59 molecule (CD59 blood group)	Homo sapiens	258-264
18166744-4	2008	RESULTS: The repeatability coefficients of CO(PAC) and CO(PW) were 0.89 L.min(-1) and 1.04 L.min(-1) respectively after induction of anesthesia, which corresponded to 24% of CO(PAC) and 26% of CO(PW), and increased to 33% of CO(PAC) and 32% of CO(PW) immediately after extracorporeal circulation.	co(pac)	43-50	CD59 molecule (CD59 blood group)	Homo sapiens	74-80
18166744-4	2008	RESULTS: The repeatability coefficients of CO(PAC) and CO(PW) were 0.89 L.min(-1) and 1.04 L.min(-1) respectively after induction of anesthesia, which corresponded to 24% of CO(PAC) and 26% of CO(PW), and increased to 33% of CO(PAC) and 32% of CO(PW) immediately after extracorporeal circulation.	co(pac)	43-50	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
18522232-8	2008	In addition, flow cytometry analysis showed that SP cells had high expression of CD13, CD29, CD44, CD46, CD49b, CD49c, CD49e, CD59, CD140a, and CD166 but low expression of CD 49d, and CD51.	sp	49-51	CD59 molecule (CD59 blood group)	Homo sapiens	126-130
17908272-9	2007	Mean serum creatinine was 1.1 +/- 0.6 mg/dL, and calculated creatinine clearance was 82.3 +/- 29.4 mL/min/1.73 m(2).	Creatinine	60-70	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
18090356-13	2008	"At-risk" tissue defined by the physiologic region of interest, however, showed a universal increase in cerebral metabolic rate of oxygen from a median (interquartile range) of 23 (22-25) micromol x 100 mL(-1) x min(-1) to 30 (28-36) micromol x 100 mL(-1) x min(-1) (p < .01).	Oxygen	131-137	CD59 molecule (CD59 blood group)	Homo sapiens	212-218
17932136-6	2008	With ATP, leg arterial-venous O(2) difference was decreased (P < 0.05) from 139.3 +/- 9.0 to 116.9 +/- 8.4(-1) and leg .VO(2max) was 20% lower compared to the control trial (1.1 +/- 0.2 versus 0.9 +/- 0.1 l min(-1)) (P = 0.069).	Adenosine Triphosphate	5-8	CD59 molecule (CD59 blood group)	Homo sapiens	210-216
18157141-3	2008	We generated two transgenic mouse strains that express human CD59 either on erythrocytes (strain ThCD59(RBC)) or on endothelia (strain ThCD59(END)).	thcd59	97-103	CD59 molecule (CD59 blood group)	Homo sapiens	61-65
18497502-8	2008	In this study, CKD was defined as <60 ml/min/1.73 m(2) of estimated creatinine clearance by the Cockcroft-Gault method.	Creatinine	71-81	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
18391509-4	2008	Sixty minutes prior to the end of surgery, we kept a fixed 2% inspired isoflurane in 6,000 ml min(-1) oxygen flow.	Oxygen	102-108	CD59 molecule (CD59 blood group)	Homo sapiens	94-100
17804123-9	2007	Phenylalanine NB improved from a negative basal value (-16+/-2) to zero (0.8+/-6 nmol min(-1) 100 ml leg(-1), P0.05) following AA.	phenylalanine nb	0-16	CD59 molecule (CD59 blood group)	Homo sapiens	86-100
18356783-9	2007	Creatinine clearance was less in the LR (7.67 +/- 3.86 ml/min/1.73 m2) vs. the ER group (8.70 +/- 3.62 ml/min/1.73 m2), but not significantly different.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
18270190-5	2007	The risk of acute renal failure significantly increases for an oxygen delivery approximately at the same value (272 mL min(-1) m(- 2)).	Oxygen	63-69	CD59 molecule (CD59 blood group)	Homo sapiens	119-125
17704291-9	2007	Similar to wall stress, glucose uptake markedly increased vs. control (0.24 +/- 0.004 vs. 0.07 +/- 0.01 micromol x min(-1) x g(-1), P < 0.05), with no significant regional differences.	Glucose	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
18031577-7	2007	Dobutamine administration produced a rapid increase in heart rate (9.4 +/- 5.9 beats/min2).	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	85-89
17963836-9	2007	In the chloride determination, a flow rate of 50 microL min(-1) was used, providing a sample frequency of 45 injection h(-1), generating ca.	Chlorides	7-15	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
17717127-4	2007	Separately, using a flow cell, the glucose concentration was varied at approximately 0.17-0.28 mmol(-1) x L(-1) x min(-1), and the sensor"s ability to continuously monitor glucose was investigated over an extended period.	Glucose	35-42	CD59 molecule (CD59 blood group)	Homo sapiens	114-120
18022082-13	2007	The low threshold for creatinine clearance appears to be 50 ml/min/1.73 m(2).	Creatinine	22-32	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
17989688-2	2007	In the rare hemolytic disease paroxysmal nocturnal hemoglobinuria (PNH), somatic mutations result in a deficiency of glycosylphosphatidylinositol-linked surface proteins, including the terminal complement inhibitor CD59, on hematopoietic stem cells.	Glycosylphosphatidylinositols	117-145	CD59 molecule (CD59 blood group)	Homo sapiens	215-219
17924658-8	2007	Kinetic parameters for the transpeptidation reaction between glutathione and glycylglycine were determined by mass spectrometry, giving a kcat of 13.4 x 10(3) min-1 and apparent KM values of 1.11 mM for glutathione and 8.1 mM for glycylglycine.	Glutathione	61-72	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
17924658-8	2007	Kinetic parameters for the transpeptidation reaction between glutathione and glycylglycine were determined by mass spectrometry, giving a kcat of 13.4 x 10(3) min-1 and apparent KM values of 1.11 mM for glutathione and 8.1 mM for glycylglycine.	Glycylglycine	77-90	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
17924658-8	2007	Kinetic parameters for the transpeptidation reaction between glutathione and glycylglycine were determined by mass spectrometry, giving a kcat of 13.4 x 10(3) min-1 and apparent KM values of 1.11 mM for glutathione and 8.1 mM for glycylglycine.	Glutathione	203-214	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
17924658-8	2007	Kinetic parameters for the transpeptidation reaction between glutathione and glycylglycine were determined by mass spectrometry, giving a kcat of 13.4 x 10(3) min-1 and apparent KM values of 1.11 mM for glutathione and 8.1 mM for glycylglycine.	Glycylglycine	230-243	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
17924658-9	2007	The GGT-mediated hydrolysis of glutathione was also studied, providing a kcat of 53 min-1 and a KM value of 7.3 microM for glutathione.	Glutathione	31-42	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	benzylamine	39-50	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	benzylamine	39-50	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	benzylamine	39-50	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	benzylamine	39-50	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	aniline	55-62	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	aniline	55-62	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	aniline	55-62	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	aniline	55-62	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	titanium dioxide	130-134	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	titanium dioxide	130-134	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	titanium dioxide	130-134	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	Platinum	218-220	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
18153996-7	2007	Rate constants for photodegradation of benzylamine and aniline were found to be 1.4 x 10(-3) min(-1) and 0.7 x 10(-3) min(-1) for TiO2 as photocatalyst, while 2.7 x 10(-3) min(-1) and 1.7 x 10(-3) min(-1) for (5 wt.%) Pt/TiO2 as photocatalyst.	titanium dioxide	221-225	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
17558516-9	2007	Correspondingly, oxygen cost of the work (38.8 +/- 13.9 ml min(-1) W(-1)) was found to be approximately 3.5 times higher.	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	59-65
17666154-8	2007	RESULTS: CO(PAC) ranged from 2.0 to 7.6 L min-1 and CO(FT) ranged from 1.9 to 8.2 L min-1.	co(pac)	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
17666154-8	2007	RESULTS: CO(PAC) ranged from 2.0 to 7.6 L min-1 and CO(FT) ranged from 1.9 to 8.2 L min-1.	co(ft)	52-58	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
17666154-10	2007	Agreement between CO(PAC) and CO(FT) was -0.26 +/- 0.87 L min-1.	co(pac)	18-25	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
17666154-10	2007	Agreement between CO(PAC) and CO(FT) was -0.26 +/- 0.87 L min-1.	co(ft)	30-36	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
17666154-11	2007	Volume expansion induced a significant increase in both CO(PAC) and CO(FT) (from 3.4 +/- 0.8 to 4.4 +/- 1.0 L min-1; P < 0.001 and from 3.9 +/- 1.2 to 5.0 +/- 1.1 L min-1; P < 0.001, respectively) and there was a significant relationship between percent change in CO(PAC) and CO(FT) following volume expansion (r = 0.722; P = 0.01).	co(pac)	56-63	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
17666154-11	2007	Volume expansion induced a significant increase in both CO(PAC) and CO(FT) (from 3.4 +/- 0.8 to 4.4 +/- 1.0 L min-1; P < 0.001 and from 3.9 +/- 1.2 to 5.0 +/- 1.1 L min-1; P < 0.001, respectively) and there was a significant relationship between percent change in CO(PAC) and CO(FT) following volume expansion (r = 0.722; P = 0.01).	co(ft)	68-74	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
17896021-2	2007	A fiber-tip cantilever transduces flow rates to optical signal readout, and we demonstrate a dynamic range from 0 to 1500 microL min(-1) for operation in water.	Water	154-159	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
17711300-4	2007	At the putative endosomal pH of 5.6, measurement of the increase in intrinsic fluorescence upon iron release from the recombinant N-lobe yields two rate constants: 8.9 min-1 and 1.3 min-1.	Iron	96-100	CD59 molecule (CD59 blood group)	Homo sapiens	168-181
17711300-4	2007	At the putative endosomal pH of 5.6, measurement of the increase in intrinsic fluorescence upon iron release from the recombinant N-lobe yields two rate constants: 8.9 min-1 and 1.3 min-1.	Iron	96-100	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
17711300-5	2007	Direct monitoring of iron release from the N-lobe at pH 5.6 (by the decrease in absorbance at 470 nm) gives a single rate constant of 9.1 min-1, definitively establishing that the faster rate constant in the fluorescent studies is due to iron release.	Iron	21-25	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
17711300-5	2007	Direct monitoring of iron release from the N-lobe at pH 5.6 (by the decrease in absorbance at 470 nm) gives a single rate constant of 9.1 min-1, definitively establishing that the faster rate constant in the fluorescent studies is due to iron release.	Iron	238-242	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
17696452-10	2007	Apparent Km and Vmax values were 17 microM and 7.2 nmol x min(-1) x cm(-2), and transport selectivity was adenosine = inosine = uridine > guanosine = cytidine > thymidine.	Adenosine	106-115	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
17696452-10	2007	Apparent Km and Vmax values were 17 microM and 7.2 nmol x min(-1) x cm(-2), and transport selectivity was adenosine = inosine = uridine > guanosine = cytidine > thymidine.	Inosine	118-125	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
17696452-10	2007	Apparent Km and Vmax values were 17 microM and 7.2 nmol x min(-1) x cm(-2), and transport selectivity was adenosine = inosine = uridine > guanosine = cytidine > thymidine.	Uridine	128-135	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
17696452-10	2007	Apparent Km and Vmax values were 17 microM and 7.2 nmol x min(-1) x cm(-2), and transport selectivity was adenosine = inosine = uridine > guanosine = cytidine > thymidine.	Guanosine	141-150	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
17696452-10	2007	Apparent Km and Vmax values were 17 microM and 7.2 nmol x min(-1) x cm(-2), and transport selectivity was adenosine = inosine = uridine > guanosine = cytidine > thymidine.	Cytidine	153-161	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
17696452-10	2007	Apparent Km and Vmax values were 17 microM and 7.2 nmol x min(-1) x cm(-2), and transport selectivity was adenosine = inosine = uridine > guanosine = cytidine > thymidine.	Thymidine	167-176	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
17825709-6	2007	RESULTS: Prophylactic hemodialysis lessened the decrease in creatinine clearance within 72 h in the dialysis group (0.4 +/- 0.9 ml/min/1.73 m(2) vs. 2.2 +/- 2.8 ml/min/1.73 m(2); p < 0.001).	Creatinine	60-70	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
17876376-7	2007	Prednisone significantly decreased serum creatinine by 52.21+/-48.68 mumol/L and increased glomerular filtration rate by 33.63+/-15.87 mL/min/1.73 m(2) compared with baseline.	Prednisone	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
17992728-8	2007	Kinetic analysis showed that the Vmax/Km values for (+)-fenchol catalysed by liver microsomes of human sample HG03 were 7.25 nM-1 min-1.	fenchol	52-63	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
17992728-9	2007	Human recombinant CYP2A6-catalyzed (+)-fenchol oxidation with a Vmax value of 6.96 nmol min-1 nmol-1 P450 and apparent Km value of 0.09 mM.	fenchol	35-46	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
17992728-13	2007	Kinetic analysis showed that the Km values for the formation of fenchone, 6-exo- hydroxyfenchol and 10-hydroxyfenchol in rats treated with phenobarbital were 0.06, 0.03 and 0.03 mM, and Vmax values were 2.94, 6.1 and 13.8 nmol min-1 nmol-1 P450, respectively.	fenchone	64-72	CD59 molecule (CD59 blood group)	Homo sapiens	227-232
17992728-13	2007	Kinetic analysis showed that the Km values for the formation of fenchone, 6-exo- hydroxyfenchol and 10-hydroxyfenchol in rats treated with phenobarbital were 0.06, 0.03 and 0.03 mM, and Vmax values were 2.94, 6.1 and 13.8 nmol min-1 nmol-1 P450, respectively.	6-exo- hydroxyfenchol	74-95	CD59 molecule (CD59 blood group)	Homo sapiens	227-232
17992728-13	2007	Kinetic analysis showed that the Km values for the formation of fenchone, 6-exo- hydroxyfenchol and 10-hydroxyfenchol in rats treated with phenobarbital were 0.06, 0.03 and 0.03 mM, and Vmax values were 2.94, 6.1 and 13.8 nmol min-1 nmol-1 P450, respectively.	10-hydroxyfenchol	100-117	CD59 molecule (CD59 blood group)	Homo sapiens	227-232
17992728-13	2007	Kinetic analysis showed that the Km values for the formation of fenchone, 6-exo- hydroxyfenchol and 10-hydroxyfenchol in rats treated with phenobarbital were 0.06, 0.03 and 0.03 mM, and Vmax values were 2.94, 6.1 and 13.8 nmol min-1 nmol-1 P450, respectively.	Phenobarbital	139-152	CD59 molecule (CD59 blood group)	Homo sapiens	227-232
17666834-6	2007	Among bipolymeric formulations, the highest first-stage release rate of 9.18 x 10(-3) min(-1) was determined for the gel consisting of 2.00% Carbopol 980NF with 1.00% methylcellulose.	carboxypolymethylene	141-149	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
17690434-2	2007	The use of diluted nitric acid as extractant in a continuous mode at a flow rate of 3.5 mL min(-1) and room temperature was sufficient for quantitative extraction of these trace metals from seafoods.	Nitric Acid	19-30	CD59 molecule (CD59 blood group)	Homo sapiens	91-97
17875963-6	2007	Although hemodialysis was performed 9 times and the urine output was satisfactory, the creatinine clearance levels increased only to about 50 mL/min/1.73 m2 (0.84 mL/s/m2) at 6 weeks following admission.	Creatinine	87-97	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
17666715-11	2007	This pilot study suggests that remifentanil intravenous PCA is efficacious for labour analgesia as a bolus of 0.25 microg x kg(-1), with a lockout interval of two minutes and continuous infusion of 0.025-0.1 microg x kg(-1) x min(-1).	Remifentanil	31-43	CD59 molecule (CD59 blood group)	Homo sapiens	226-232
27771888-11	2007	This pilot study suggests that remifentanil intravenous PCA is efficacious for labour analgesia as a bolus of 0.25 mug kg-1, with a lockout interval of two minutes and continuous infusion of 0.025-0.1 mug kg-1 min-1.	Remifentanil	31-43	CD59 molecule (CD59 blood group)	Homo sapiens	210-215
17490711-4	2007	An inlet gas stream of 10 l min(-1) containing 0.50+/-0.02 ppm toluene was treated by the plasma reactor in atmospheric conditions.	Toluene	63-70	CD59 molecule (CD59 blood group)	Homo sapiens	28-34
17425514-4	2007	Our results show an increase in insulin-mediated glucose disposal during euglycaemic clamp conditions that was significantly higher following the high-salt diet compared with the low-salt diet (7.41+/-0.41 compared with 6.11+/-0.40 mg x kg(-1) of body weight x min(-1) respectively; P=0.03).	Glucose	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	261-267
17425514-4	2007	Our results show an increase in insulin-mediated glucose disposal during euglycaemic clamp conditions that was significantly higher following the high-salt diet compared with the low-salt diet (7.41+/-0.41 compared with 6.11+/-0.40 mg x kg(-1) of body weight x min(-1) respectively; P=0.03).	Salts	151-155	CD59 molecule (CD59 blood group)	Homo sapiens	261-267
17926407-9	2007	Comparison of different phosphorous loss rate under different rainfall intensities suggested that loss rate of TP and DP under 2.50 mm x min(-1) was 20 times and 33 times higher than that under 0.83 mm x min(-1), which showed that loss rate of PP and DP increased with the increase of rainfall intensities.	tp	111-113	CD59 molecule (CD59 blood group)	Homo sapiens	137-143
17926407-9	2007	Comparison of different phosphorous loss rate under different rainfall intensities suggested that loss rate of TP and DP under 2.50 mm x min(-1) was 20 times and 33 times higher than that under 0.83 mm x min(-1), which showed that loss rate of PP and DP increased with the increase of rainfall intensities.	tp	111-113	CD59 molecule (CD59 blood group)	Homo sapiens	204-210
17926407-9	2007	Comparison of different phosphorous loss rate under different rainfall intensities suggested that loss rate of TP and DP under 2.50 mm x min(-1) was 20 times and 33 times higher than that under 0.83 mm x min(-1), which showed that loss rate of PP and DP increased with the increase of rainfall intensities.	dp	118-120	CD59 molecule (CD59 blood group)	Homo sapiens	137-143
17926407-9	2007	Comparison of different phosphorous loss rate under different rainfall intensities suggested that loss rate of TP and DP under 2.50 mm x min(-1) was 20 times and 33 times higher than that under 0.83 mm x min(-1), which showed that loss rate of PP and DP increased with the increase of rainfall intensities.	dp	251-253	CD59 molecule (CD59 blood group)	Homo sapiens	137-143
17725176-5	2007	RESULTS: Coadministration of probenecid resulted in a 34% reduction of the renal clearance of 1-MX (mean +/- SD 190 +/- 42 versus 290 +/- 83 ml min(-1), 95% CI on difference 0.2, 200, p = 0.04) with a 41% reduction in its estimated non-glomerular clearance.	Probenecid	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	144-150
17507141-3	2007	The Lund University Cardiopulmonary Assist System (LUCAS) device is driven by > 70 l min(-1) oxygen which is also likely to increase ambient oxygen concentrations and cause similar risk of fire and explosion.	Oxygen	96-102	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
17507141-3	2007	The Lund University Cardiopulmonary Assist System (LUCAS) device is driven by > 70 l min(-1) oxygen which is also likely to increase ambient oxygen concentrations and cause similar risk of fire and explosion.	Oxygen	144-150	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
17510190-14	2007	Uterine artery O(2) delivery in these pregnancies was 99 +/- 3 ml min(-1), approximately 5-fold greater than near-term fetal O(2) consumption.	Oxygen	15-19	CD59 molecule (CD59 blood group)	Homo sapiens	66-72
17581135-10	2007	Specific inhibition of Src kinases with PP2, attenuated pH(i) recovery rate from 1.93 +/- 0.16 pH units min(-1) (normotonic environment) to 1.02 +/- 0.50 pH units min(-1) (hypotonic environment).	pp2	40-43	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
17569508-7	2007	The ATPase activity was stimulated by bile acids and glucuronide conjugates, reaching 170 +/- 28 nmol min-1 mg-1, but was not stimulated by a variety of anticancer drugs.	Bile Acids and Salts	38-48	CD59 molecule (CD59 blood group)	Homo sapiens	102-112
17569508-7	2007	The ATPase activity was stimulated by bile acids and glucuronide conjugates, reaching 170 +/- 28 nmol min-1 mg-1, but was not stimulated by a variety of anticancer drugs.	Glucuronides	53-64	CD59 molecule (CD59 blood group)	Homo sapiens	102-112
17623109-5	2007	After glutamine restoration, MCF7 and Bcap37 cells were synchronized into the G2/M phase and an average increased expression of CD59 and CD55 occurred with a corresponding resistance to complement-mediated damage.	Glutamine	6-15	CD59 molecule (CD59 blood group)	Homo sapiens	128-132
17581135-10	2007	Specific inhibition of Src kinases with PP2, attenuated pH(i) recovery rate from 1.93 +/- 0.16 pH units min(-1) (normotonic environment) to 1.02 +/- 0.50 pH units min(-1) (hypotonic environment).	pp2	40-43	CD59 molecule (CD59 blood group)	Homo sapiens	163-169
17679571-6	2007	Bottled oxygen delivered at 2 L x min(-1) via nasal cannula was prescribed for her journey.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	34-40
17637192-9	2007	0.1 M HCl at 50 rev min(-1) was found to be the most discriminating dissolution method.	Hydrochloric Acid	6-9	CD59 molecule (CD59 blood group)	Homo sapiens	20-26
17502492-8	2007	Renal oxygen consumption and acetate turnover varied on a wide range from 0.05 to 0.29 mmol min(-1) (>5-fold) and from 0.025 to 0.188 minutes(-1) (>7-fold), respectively.	Oxygen	6-12	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
17502492-8	2007	Renal oxygen consumption and acetate turnover varied on a wide range from 0.05 to 0.29 mmol min(-1) (>5-fold) and from 0.025 to 0.188 minutes(-1) (>7-fold), respectively.	Acetates	29-36	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
17531319-4	2007	The deduced LycCD59 protein shared the structural feature of mammalian CD59, including a conserved cysteine skeleton responsible for the formation of disulfide bonds, and a similar pattern of hydrophobic termini.	Cysteine	99-107	CD59 molecule (CD59 blood group)	Homo sapiens	15-19
17531319-4	2007	The deduced LycCD59 protein shared the structural feature of mammalian CD59, including a conserved cysteine skeleton responsible for the formation of disulfide bonds, and a similar pattern of hydrophobic termini.	Disulfides	150-159	CD59 molecule (CD59 blood group)	Homo sapiens	15-19
17590070-7	2007	Mean average oxygen flow rate was 1.00 +/- 0.17 L x min(-1).	Oxygen	13-19	CD59 molecule (CD59 blood group)	Homo sapiens	52-58
17252544-1	2007	Nitric oxide (NO) is released by endothelial cells that line the inner walls of healthy blood vessels at fluxes ranging from 0.5 x 10(-10) to 4.0 x 10(-10) mol cm(-2) min(-1), and this continuous NO release contributes to the extraordinary thromboresistance of the intact endothelium.	Nitric Oxide	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	167-173
17252544-7	2007	The highest NO flux tested, 7.05 (+/-0.25) x 10(-10) mol cm(-2) min(-1), effectively reduced platelet adhesion to nearly 20% of its original level (from 14.0 (+/-2.1) x 10(5) cells cm(-2) to 2.96 (+/-0.18) x 10(5) cells cm(-2)) compared to the control polymer coating without NO release capability.	Polymers	252-259	CD59 molecule (CD59 blood group)	Homo sapiens	64-70
17513631-9	2007	Coadministration of remifentanil led to synergistic analgesic effects (to 62% +/- 26% and 58% +/- 25% of control, for 0.025 or 0.05 microg x kg(-1) x min(-1), respectively), but upon withdrawal, pain and hyperalgesia increased above control level.	Remifentanil	20-32	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
17517965-4	2007	Therefore, we propose that the CD59 cluster in STALL may be a key, albeit transient, platform for transducing the extracellular GPI-AR signal to the intracellular IP(3)-Ca(2+) signal, via PLCgamma2 recruitment.	Inositol 1,4,5-Trisphosphate	163-168	CD59 molecule (CD59 blood group)	Homo sapiens	31-35
17390126-4	2007	Methanol, at flow rates of 0.48, 1.5, and 2.5 mL min(-1), respectively, was used as mobile phase for isocratic elution of the compounds in the three methods.	Methanol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
17517965-5	2007	The prolonged, analogue, bulk IP(3)-Ca(2+) signal, which lasts for more than several minutes, is likely generated by the sum of the short-lived, digital-like IP(3) bursts, each created by the transient recruitment of PLCgamma2 molecules to STALLed CD59.	Inositol 1,4,5-Trisphosphate	30-35	CD59 molecule (CD59 blood group)	Homo sapiens	248-252
17492567-12	2007	All creatinine-based formulae showed a high sensitivity and specifity for diagnosing a GFR below 60 ml/min/1,73m (2).	Creatinine	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
17426069-1	2007	BACKGROUND: High-dose remifentanil (1-5 microg kg-1 min-1), commonly used for cardiac surgery, has been associated with muscle rigidity, hypotension, bradycardia, and reduced cardiac output.	Remifentanil	22-34	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
17426069-11	2007	CONCLUSIONS: Remifentanil at 0.3 and 0.4 microg kg-1 min-1 in combination with a target-controlled propofol infusion in the pre-bypass period is well tolerated.	Remifentanil	13-25	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
17329996-4	2007	Mirtazapine was enantioselectively absorbed from the gut with a rate constant of 0.2 min-1 for S+, but 0.08 min-1 for R- mirtazapine.	Mirtazapine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
17329996-4	2007	Mirtazapine was enantioselectively absorbed from the gut with a rate constant of 0.2 min-1 for S+, but 0.08 min-1 for R- mirtazapine.	Mirtazapine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
17329996-4	2007	Mirtazapine was enantioselectively absorbed from the gut with a rate constant of 0.2 min-1 for S+, but 0.08 min-1 for R- mirtazapine.	Sulfur	95-97	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
17292967-6	2007	Nitrogen was used as carrier gas at a flow-rate of 2 ml min(-1).	Nitrogen	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
17430481-8	2007	The mean creatinine clearance at one year post-KT was 91.3 +/- 38.1 mls/min/1.73 m(2), with a projected graft life expectancy of 18.4 years.	Creatinine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
17452893-6	2007	A larger than 10 mL/min 1.73 m decrease in glomerular filtration rate was observed in more patients on CsA than on MMF (73% vs. 29%, P=0.019).	Cyclosporine	103-106	CD59 molecule (CD59 blood group)	Homo sapiens	20-25
17353002-6	2007	Prominent superoxide generation was observed with an initial rate of 295 nmol min(-1) mg(-1).	Superoxides	10-20	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
17353002-7	2007	Electrochemical measurements of oxygen consumption and hydrogen peroxide formation yielded values of 650 and 355 nmol min(-1) mg(-1).	Oxygen	32-38	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
17353002-7	2007	Electrochemical measurements of oxygen consumption and hydrogen peroxide formation yielded values of 650 and 355 nmol min(-1) mg(-1).	Hydrogen Peroxide	55-72	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
16391888-5	2007	Dyspnea, Raynaud"s phenomenon, and pulmonary hypertension improved with low-dose epoprostenol (3.0 to 4.0 ng kg(-1) min(-1)).	Epoprostenol	81-93	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
16391888-8	2007	It appears that pulmonary hypertension can be controlled with low-dose epoprostenol such as 3.0 to 4.0 ng kg(-1) min(-1) in some rheumatic patients.	Epoprostenol	71-83	CD59 molecule (CD59 blood group)	Homo sapiens	113-119
17425752-7	2007	Creatinine clearance after a mean follow-up of two yr was 100.7 mL/min/1.73 m(2) and 57.9 mL/min/1.73 m(2) in patients with systemic and localized TMA, respectively.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
17425444-5	2007	RESULTS: Non-insulin-mediated glucose disposal increased during the luteal phase (0.009 +/- 0.004 min(1)) versus the follicular phase (0.005 +/- 0.003 min(1)) (P < 0.05).	Glucose	30-37	CD59 molecule (CD59 blood group)	Homo sapiens	98-104
17425444-5	2007	RESULTS: Non-insulin-mediated glucose disposal increased during the luteal phase (0.009 +/- 0.004 min(1)) versus the follicular phase (0.005 +/- 0.003 min(1)) (P < 0.05).	Glucose	30-37	CD59 molecule (CD59 blood group)	Homo sapiens	151-157
17441447-4	2007	After hemodynamics were stabilized in ICU, DEX was infused at a rate of 0.3-0.5 microg x kg(-1) min(-1), following initial loading (0.5 microg x kg(-1) over 10 min).	Dexmedetomidine	43-46	CD59 molecule (CD59 blood group)	Homo sapiens	96-102
17441447-8	2007	After discontinuation of DEX, HR was significantly increased from 109 +/- 17 to 124 +/- 19 beats x min(-1) (mean +/- SD) (P < 0.05).	Dexmedetomidine	25-28	CD59 molecule (CD59 blood group)	Homo sapiens	99-105
17325594-4	2007	In group A patients, dobutamine was administered at a starting dose of 5 microg x kg(-1) x min(-1) increased to 10, 20 and 30 microg x kg(-1) x min(-1) to a maximum dose of 40 microg x kg(-1) x min(-1) at 3 min intervals until the target heart rate (THR, 85% of age predicted maximum heart rate) or other standard end point criteria were achieved.	Dobutamine	21-31	CD59 molecule (CD59 blood group)	Homo sapiens	91-97
17325594-7	2007	The mean dose of dobutamine infused in group A was significantly higher than in group B (36.2 vs. 23.5 microg x kg(-1) x min(-1), P<0.01).	Dobutamine	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	121-127
17064863-7	2007	However, the salbutamol sulphate blends containing either "fresh" or "aged" components were only characterized using LD at 60 l min(-1).	Albuterol	13-32	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
17425752-7	2007	Creatinine clearance after a mean follow-up of two yr was 100.7 mL/min/1.73 m(2) and 57.9 mL/min/1.73 m(2) in patients with systemic and localized TMA, respectively.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
17315739-6	2007	Heart rate was around 130 beats x min(-1), and the landiolol was given continuously at a rate of 0.02-0.04 microg x kg(-1) x min(-1).	landiolol	51-60	CD59 molecule (CD59 blood group)	Homo sapiens	125-131
17366925-7	2007	Oxygen 6 l x min(-1) was adminisitered to prevent both desaturation of patient and fogging of blade during intubation procedure.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	13-19
17177114-6	2007	RESULTS: Salbutamol FPFs of all carrier-based formulations were found to increase by increasing the initial flow increase rate (FIR) from 200 to 600 l min(-1) s(-1) although they could be placed in an increasing order of maltose blend < sorbitol blend < lactose blend.	Albuterol	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	151-157
17234541-6	2007	The relative densities of cell-surface expression obtained from cs-ELISAs of CRFs on OSCCs are as follows: CD59 > CD55 > CD46.	Cesium	64-66	CD59 molecule (CD59 blood group)	Homo sapiens	107-111
17177114-8	2007	For the Bricanyl Turbohaler, increasing FIR from 120 to 600 l min(-1) s(-1) for a constant peak flow rate (PFR) of 60 l min(-1) increased the mean Terbutaline FPF from 18.2% to 45.5%.	bricanyl turbohaler	8-27	CD59 molecule (CD59 blood group)	Homo sapiens	120-126
17177114-8	2007	For the Bricanyl Turbohaler, increasing FIR from 120 to 600 l min(-1) s(-1) for a constant peak flow rate (PFR) of 60 l min(-1) increased the mean Terbutaline FPF from 18.2% to 45.5%.	Terbutaline	147-158	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
17177114-8	2007	For the Bricanyl Turbohaler, increasing FIR from 120 to 600 l min(-1) s(-1) for a constant peak flow rate (PFR) of 60 l min(-1) increased the mean Terbutaline FPF from 18.2% to 45.5%.	Terbutaline	147-158	CD59 molecule (CD59 blood group)	Homo sapiens	120-126
17289551-2	2007	Two of these regulators in humans, CD55 and CD59, are glycosylphosphatidylinositol-anchored, type I cell surface proteins, which inhibit formation of the C3 convertases and prevent the terminal polymerization of the membrane attack complex, respectively.	Glycosylphosphatidylinositols	54-82	CD59 molecule (CD59 blood group)	Homo sapiens	44-48
17727303-15	2007	Treatment with ciclosporin should be limited to patients with a relatively normal renal function (GFR >60 mL/min/1.73m(2)) in view of its nephrotoxicity in patients with renal dysfunction.	Cyclosporine	15-26	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
16884774-3	2007	Functionally, the role of CD59 in complement regulation is well-defined but studies have also shown clear evidence for signalling properties, which are linked to its glycophosphatidyl inositol (GPI) anchor and its location within lipid rafts.	glycophosphatidyl inositol	166-192	CD59 molecule (CD59 blood group)	Homo sapiens	26-30
16884774-3	2007	Functionally, the role of CD59 in complement regulation is well-defined but studies have also shown clear evidence for signalling properties, which are linked to its glycophosphatidyl inositol (GPI) anchor and its location within lipid rafts.	GPI 1046	194-197	CD59 molecule (CD59 blood group)	Homo sapiens	26-30
16884774-4	2007	Cross-linking of CD59 using specific monoclonal antibodies drives both calcium release and activation of lipid-raft associated signalling molecules such as tyrosine kinases.	Calcium	71-78	CD59 molecule (CD59 blood group)	Homo sapiens	17-21
17184435-14	2007	The mean dose of thiopental required to warrant patient immobility was 0.227 +/- 0.053 mg x kg(-1) x min(-1) of procedure in T_MLD patients and 0.119 +/- 0.061 mg x kg(-1) x min(-1) of procedure in T_HLT patients (difference not significant).	Thiopental	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
17184435-14	2007	The mean dose of thiopental required to warrant patient immobility was 0.227 +/- 0.053 mg x kg(-1) x min(-1) of procedure in T_MLD patients and 0.119 +/- 0.061 mg x kg(-1) x min(-1) of procedure in T_HLT patients (difference not significant).	Thiopental	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	174-180
17184435-15	2007	The mean dose of propofol required for immobility was 0.119 +/- 0.054 mg x kg(-1) x min(-1) of procedure in T_MLD patients and 0.115 +/- 0.043 mg x kg(-1) x min(-1) of procedure in T_HLT patients (difference not significant).	Propofol	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
17184435-15	2007	The mean dose of propofol required for immobility was 0.119 +/- 0.054 mg x kg(-1) x min(-1) of procedure in T_MLD patients and 0.115 +/- 0.043 mg x kg(-1) x min(-1) of procedure in T_HLT patients (difference not significant).	Propofol	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	157-163
17852801-6	2007	RESULTS: There was good correlation between eGFRCystC and iohexol clearance (r = 0.88) in patients with iohexol clearance <30 mL/min/1.73 m2 and none of the patients had a difference between eGFRCystC and iohexol clearance exceeding 50 %.	Iohexol	58-65	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
17852801-6	2007	RESULTS: There was good correlation between eGFRCystC and iohexol clearance (r = 0.88) in patients with iohexol clearance <30 mL/min/1.73 m2 and none of the patients had a difference between eGFRCystC and iohexol clearance exceeding 50 %.	egfrcystc	44-53	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
17134154-6	2006	For a solvent of 50:50 methanol/water (v/v), lowering the flow from 200 to 50 microL min-1 results in a 10x increase in charge exchange ionization efficiency--further flow reductions provide even greater enhancements.	Methanol	23-31	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
17134154-6	2006	For a solvent of 50:50 methanol/water (v/v), lowering the flow from 200 to 50 microL min-1 results in a 10x increase in charge exchange ionization efficiency--further flow reductions provide even greater enhancements.	Water	32-37	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
16645840-10	2006	(123)I-OIH-Cl at birth (age=0) was 81 ml/min/1.73 m(2) BSA.	oih-cl	7-13	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
16942848-12	2006	At 28.3 l min(-1) a significant linear correlation was found between the fine fractions measured by laser diffraction and the salbutamol fine fractions determined by inertial impaction (R(2)=87.4%, p=0.02, ANOVA).	Albuterol	126-136	CD59 molecule (CD59 blood group)	Homo sapiens	10-16
16973702-9	2006	The increase in HR response to isoproterenol infusion was blunted post-exercise at both 4 and 6 microg kg min-1 (127+/-7 and 132+/-6 beats min-1) compared with pre-exercise (138+/-8 and 141+/-12 beats min-1, P<0.05).	Isoproterenol	31-44	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
16973702-9	2006	The increase in HR response to isoproterenol infusion was blunted post-exercise at both 4 and 6 microg kg min-1 (127+/-7 and 132+/-6 beats min-1) compared with pre-exercise (138+/-8 and 141+/-12 beats min-1, P<0.05).	Isoproterenol	31-44	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
16973702-9	2006	The increase in HR response to isoproterenol infusion was blunted post-exercise at both 4 and 6 microg kg min-1 (127+/-7 and 132+/-6 beats min-1) compared with pre-exercise (138+/-8 and 141+/-12 beats min-1, P<0.05).	Isoproterenol	31-44	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
17146123-7	2006	The results obtained in our experimental investigations have shown that a distance of 1.5 cm between the detector and the filter, an absorber layer of Al with a thickness of 12 microm and an air flow rate of 4 l min(-1) offer the best design parameters for a high efficiency radon dosimeter.	Aluminum	151-153	CD59 molecule (CD59 blood group)	Homo sapiens	212-218
17035949-10	2006	However, by the end of 1 year the monthly rate of decrease in estimated glomerular filtration rate from baseline was lower in patients treated with spironolactone than in controls (0.323+/-0.044 vs 0.474+/-0.037 ml/min/1.73 m(2), P<0.01).	Spironolactone	148-162	CD59 molecule (CD59 blood group)	Homo sapiens	215-220
17190316-6	2006	In the landiolol group, 0.125 mg x kg)-1) x min(-1) of landiolol for 1 minute was administered immediately after neostigmine-atropine injection.	landiolol	55-64	CD59 molecule (CD59 blood group)	Homo sapiens	44-50
17023150-5	2006	The subjects were exposed on each occasion for 1h during intermittent exercise at a ventilation of 40l min-1.	Hydrogen	47-49	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
17162469-3	2006	The systemic clearance values of muraglitazar in the mouse, rat, dog, and cynomolgus monkey were 1.2, 3.0, 12.3 and 1.2 ml min-1 kg-1, respectively.	muraglitazar	33-45	CD59 molecule (CD59 blood group)	Homo sapiens	123-133
17162469-7	2006	The systemic plasma clearance of muraglitazar in humans was predicted to be approximately 12-14 ml min-1 kg-1 based on allometry or by scaling of in vitro clearance parameters.	muraglitazar	33-45	CD59 molecule (CD59 blood group)	Homo sapiens	99-109
16959858-5	2006	A 100% increase in the chemoreflex gain (from 800 l min(-1) (fraction CO(2))(-1)) resulted in an increase in loop gain of 275 +/- 6% (P < 0.0001) across a wide range of values of steady state CO(2) and apnoea thresholds.	co(2))	70-76	CD59 molecule (CD59 blood group)	Homo sapiens	52-58
16959858-5	2006	A 100% increase in the chemoreflex gain (from 800 l min(-1) (fraction CO(2))(-1)) resulted in an increase in loop gain of 275 +/- 6% (P < 0.0001) across a wide range of values of steady state CO(2) and apnoea thresholds.	co(2)	70-75	CD59 molecule (CD59 blood group)	Homo sapiens	52-58
16978312-3	2006	The common approach of inserting a 14-gauge cannula and using low-pressure ventilation via intermittent occlusion of an opening in oxygen tubing (15 l x min(-1) flow) results in ineffective ventilation within 60 s or less, depending on the degree of airway obstruction.	Oxygen	131-137	CD59 molecule (CD59 blood group)	Homo sapiens	153-159
17002574-4	2006	INTRODUCTION: 25-Hydroxyvitamin D deficiency (<37 nM) is common in patients with chronic kidney disease (CKD) stage 5 (glomerular filtration rate < 15 ml/min/1.73 m(2) or on dialysis), but it is unclear if this deficiency is associated with bone disease and if supplementation is warranted.	25-hydroxyvitamin D	14-33	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
17140255-6	2006	The cellular uptake of D-lactate and butyrate exhibited pH- and concentration-dependence (D-lactate, Km of 26.5 +/- 2.2 mM and Vmax of 72.0 +/- 14.5 nmol mg-1 min-1; butyrate, Km of 0.8 +/- 0.3 mM, Vmax of 29.3 +/- 2.5 nmol mg-1 min-1, and a diffusional clearance of 2.1 microL mg-1 min-1).	Lactic Acid	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
17140255-6	2006	The cellular uptake of D-lactate and butyrate exhibited pH- and concentration-dependence (D-lactate, Km of 26.5 +/- 2.2 mM and Vmax of 72.0 +/- 14.5 nmol mg-1 min-1; butyrate, Km of 0.8 +/- 0.3 mM, Vmax of 29.3 +/- 2.5 nmol mg-1 min-1, and a diffusional clearance of 2.1 microL mg-1 min-1).	Lactic Acid	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	229-234
17140255-6	2006	The cellular uptake of D-lactate and butyrate exhibited pH- and concentration-dependence (D-lactate, Km of 26.5 +/- 2.2 mM and Vmax of 72.0 +/- 14.5 nmol mg-1 min-1; butyrate, Km of 0.8 +/- 0.3 mM, Vmax of 29.3 +/- 2.5 nmol mg-1 min-1, and a diffusional clearance of 2.1 microL mg-1 min-1).	Lactic Acid	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	229-234
17140255-6	2006	The cellular uptake of D-lactate and butyrate exhibited pH- and concentration-dependence (D-lactate, Km of 26.5 +/- 2.2 mM and Vmax of 72.0 +/- 14.5 nmol mg-1 min-1; butyrate, Km of 0.8 +/- 0.3 mM, Vmax of 29.3 +/- 2.5 nmol mg-1 min-1, and a diffusional clearance of 2.1 microL mg-1 min-1).	Butyrates	37-45	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
17140255-6	2006	The cellular uptake of D-lactate and butyrate exhibited pH- and concentration-dependence (D-lactate, Km of 26.5 +/- 2.2 mM and Vmax of 72.0 +/- 14.5 nmol mg-1 min-1; butyrate, Km of 0.8 +/- 0.3 mM, Vmax of 29.3 +/- 2.5 nmol mg-1 min-1, and a diffusional clearance of 2.1 microL mg-1 min-1).	Butyrates	37-45	CD59 molecule (CD59 blood group)	Homo sapiens	229-234
17140255-6	2006	The cellular uptake of D-lactate and butyrate exhibited pH- and concentration-dependence (D-lactate, Km of 26.5 +/- 2.2 mM and Vmax of 72.0 +/- 14.5 nmol mg-1 min-1; butyrate, Km of 0.8 +/- 0.3 mM, Vmax of 29.3 +/- 2.5 nmol mg-1 min-1, and a diffusional clearance of 2.1 microL mg-1 min-1).	Butyrates	37-45	CD59 molecule (CD59 blood group)	Homo sapiens	229-234
17111008-6	2006	This was further supported by the fact that 7 tests exhibited peak oxygen uptake values over 100 mL.min(-1) (>or= 3%) lower than the peak values attained in the incremental phase.	Oxygen	67-73	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
16873387-4	2006	RESULTS: The rate of oxygen desaturation of haemoglobin from 90 to 40% was similar across the ages studied, being approximately 30% min(-1).	Oxygen	21-27	CD59 molecule (CD59 blood group)	Homo sapiens	132-138
17072091-9	2006	Study 2: After the administration of atropine, CO was significantly increased from 4.28+/-0.83 to 5.76+/-1.55 l min(-1) (p<0.0001).	Atropine	37-45	CD59 molecule (CD59 blood group)	Homo sapiens	112-118
17144261-3	2006	The volumetric oxygen transfer coefficient (kLa) values for superficial air velocities between 8.4 cm min(-1) and 57.0 cm min(-1) varied from 20.8 h(-1) to 58.8 h(-1) for tap water, and 16.8 h(-1) to 53.0 h(-1) for the anaerobic pre-treated effluent.	Oxygen	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
17144261-3	2006	The volumetric oxygen transfer coefficient (kLa) values for superficial air velocities between 8.4 cm min(-1) and 57.0 cm min(-1) varied from 20.8 h(-1) to 58.8 h(-1) for tap water, and 16.8 h(-1) to 53.0 h(-1) for the anaerobic pre-treated effluent.	Oxygen	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	122-128
17000295-13	2006	We observed that a flow rate of 80 mL x kg(-1) x min(-1) improved brain oxygenation and prevented an increase in extracellular dopamine release.	Dopamine	127-135	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
17051993-10	2006	Epinephrine at 0.005-0.02 microg x kg(-1) x min(-1) was infused continuously to maintain his blood pressure.	Epinephrine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	44-50
16934049-5	2006	Torsemide renal clearance ranged from 6.5 to 43.1 ml min(-1) with a log-normal distribution and a geometric mean of 15.6 ml min(-1) (15.0-16.1 +/- SEM).	Torsemide	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	53-59
16685518-5	2006	At a normal flow rate of 50 microL min(-1), the produced HMA-based monolithic columns typically exhibited 3,000 theoretical plates for a 20-cm-long column, and the pressure drop was generally less than 1 MPa per 20 cm.	hexyl methacrylate	57-60	CD59 molecule (CD59 blood group)	Homo sapiens	35-41
16844690-3	2006	Previous studies indicated that the CD59 binding site in C9 was located within a 25-residue disulfide-bonded loop, and in C8alpha was located within a 51-residue sequence that overlaps the CD59 binding region of C9.	Disulfides	92-101	CD59 molecule (CD59 blood group)	Homo sapiens	36-40
16934049-5	2006	Torsemide renal clearance ranged from 6.5 to 43.1 ml min(-1) with a log-normal distribution and a geometric mean of 15.6 ml min(-1) (15.0-16.1 +/- SEM).	Torsemide	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	124-130
16934049-7	2006	AA carriers of the polymorphism rs11231809 in SLC22A11 had a torsemide renal clearance of 13.3 ml min(-1) (12.7-13.9) compared with 15.1 ml min(-1) (14.5-15.8) in AT and 18.0 ml min(-1) (16.7-19.5) in TT carriers (P = 0.002).	Torsemide	61-70	CD59 molecule (CD59 blood group)	Homo sapiens	98-104
16918654-8	2006	RESULTS: A mean increase in ventilation of 1.42 (0.38) l x min(-1) was required to maintain a normal P(E)CO(2) level.	Carbon Dioxide	105-110	CD59 molecule (CD59 blood group)	Homo sapiens	59-65
17048507-6	2006	The use of the liposome and cyclodextrin inclusion complexes resulted in a mean drug recovery of 77 and more then 90% respectively, after a light exposure until to 30 minutes with an intensity of 21 kJ x min(-1) m(-2).	Cyclodextrins	28-40	CD59 molecule (CD59 blood group)	Homo sapiens	204-210
16805935-13	2006	Mean necessary mivacurium infusion rate was 7.0 +/- 2.2 microg kg-1 min-1.	Mivacurium	15-25	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
16771812-4	2006	Mean residual creatinine clearance at transplantation of these patients was 8 mL/min/1.73 m(2).	Creatinine	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
16627603-5	2006	RESULTS: As expected, increasing the blood glucose from 7.8 to 13.3 mmol l(-1) during the glucose clamps resulted in a steep increase of urinary glucose excretion from 0.06 to 0.77 mmol min(-1).	Glucose	43-50	CD59 molecule (CD59 blood group)	Homo sapiens	186-192
16627603-5	2006	RESULTS: As expected, increasing the blood glucose from 7.8 to 13.3 mmol l(-1) during the glucose clamps resulted in a steep increase of urinary glucose excretion from 0.06 to 0.77 mmol min(-1).	Glucose	90-97	CD59 molecule (CD59 blood group)	Homo sapiens	186-192
16941994-6	2006	The maximum carbon conversion of 14.54% was obtained when the percentage of seeding was set at 14.5%, the air suction rate was set at 2.6 L kg(-1) dry-solid min(-1), and the agitator operated half of the time, alternating on and off for every 5 min.	Carbon	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	157-163
16891247-2	2006	Vmax, Km, and CLint values for glutathione conjugation of C52 (R-stereoisomer) were 0.10 +/- 0.01 nmol min-1 mg-1, 3.24 +/- 0.23 microM, and (3.15 +/- 0.09) x 10(-2) ml min-1 mg-1, respectively, in human cytosol.	Glutathione	31-42	CD59 molecule (CD59 blood group)	Homo sapiens	103-113
16891247-2	2006	Vmax, Km, and CLint values for glutathione conjugation of C52 (R-stereoisomer) were 0.10 +/- 0.01 nmol min-1 mg-1, 3.24 +/- 0.23 microM, and (3.15 +/- 0.09) x 10(-2) ml min-1 mg-1, respectively, in human cytosol.	Glutathione	31-42	CD59 molecule (CD59 blood group)	Homo sapiens	169-179
16769036-6	2006	The most potent inhibitor of DPP-IV and seprase was found to be Gly-ProP(OPh)2, which exhibited overall second-order rate constants of inactivation of 5.24 x 105 M-1 min-1 and 1.06 x 104 M-1 min-1 against DPP-IV and seprase, respectively.	gly-prop(oph)2	64-78	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
16804098-12	2006	CONCLUSIONS: In patients with a calculated creatinine clearance less than 51 mL/min/1.73 m(2), dosing according to their renal function can be improved.	Creatinine	43-53	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
16842384-6	2006	RESULTS: The rate of conversion of irinotecan (9.6 microm) was lower in tumour tissue than matched normal colon mucosa samples (0.30+/-0.14 pmol min-1 mg-1 protein and 0.77+/-0.59 pmol min-1 mg-1 protein, respectively; P<0.005).	Irinotecan	35-45	CD59 molecule (CD59 blood group)	Homo sapiens	145-155
16842384-6	2006	RESULTS: The rate of conversion of irinotecan (9.6 microm) was lower in tumour tissue than matched normal colon mucosa samples (0.30+/-0.14 pmol min-1 mg-1 protein and 0.77+/-0.59 pmol min-1 mg-1 protein, respectively; P<0.005).	Irinotecan	35-45	CD59 molecule (CD59 blood group)	Homo sapiens	185-195
16836698-6	2006	Peak oxygen consumption in the study population was 2.42 (+/-0.74) l min(-1) and subjects achieved 101 +/- 7% of this value during the measurement of .	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	69-75
16817851-4	2006	20-Hydroxyvitamin D2 was produced at a rate of 0.34 mol x min(-1) x mol(-1) P450scc, and 17,20-dihydroxyvitamin D2 was produced at a rate of 0.13 mol x min(-1) x mol(-1).	20-hydroxyvitamin D2	0-20	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
16827894-2	2006	CD55 & CD59, two glycosylphosphatidylinositol (GPI)-anchored proteins, have been detected previously in some studies also in the acrosomal region of chemically fixed spermatozoa but never demonstrated at this site on unfixed spermatozoa.	Adenosine Monophosphate	6-9	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
16827894-2	2006	CD55 & CD59, two glycosylphosphatidylinositol (GPI)-anchored proteins, have been detected previously in some studies also in the acrosomal region of chemically fixed spermatozoa but never demonstrated at this site on unfixed spermatozoa.	Glycosylphosphatidylinositols	21-49	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
16827894-2	2006	CD55 & CD59, two glycosylphosphatidylinositol (GPI)-anchored proteins, have been detected previously in some studies also in the acrosomal region of chemically fixed spermatozoa but never demonstrated at this site on unfixed spermatozoa.	Glycosylphosphatidylinositols	51-54	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
16827894-7	2006	Both CD55 & CD59 were released from the IAM by PI-PLC, demonstrating them to be GPI-anchored.	Adenosine Monophosphate	11-14	CD59 molecule (CD59 blood group)	Homo sapiens	16-20
16827894-7	2006	Both CD55 & CD59 were released from the IAM by PI-PLC, demonstrating them to be GPI-anchored.	Glycosylphosphatidylinositols	84-87	CD59 molecule (CD59 blood group)	Homo sapiens	16-20
16827894-9	2006	Antibody-induced membrane rafting and release of CD55 & CD59 in vitro may have influenced previous results.	Adenosine Monophosphate	55-58	CD59 molecule (CD59 blood group)	Homo sapiens	60-64
16817851-4	2006	20-Hydroxyvitamin D2 was produced at a rate of 0.34 mol x min(-1) x mol(-1) P450scc, and 17,20-dihydroxyvitamin D2 was produced at a rate of 0.13 mol x min(-1) x mol(-1).	17,20-dihydroxyvitamin D2	89-114	CD59 molecule (CD59 blood group)	Homo sapiens	152-158
16883879-5	2006	With a sample loading flow rate of 4.4 mL x min(-1) and a preconcentration time of 90 s, the enhancement factor was 34 (for Cu) and 36 (for Cd) as compared with the conventional FAAS method.	Cadmium	140-142	CD59 molecule (CD59 blood group)	Homo sapiens	44-50
16834667-3	2006	The serum creatinine level was 1.6 mg/dL with a creatinine clearance of 27.3 mL/min/1.48 m(2) just prior to pregnancy.	Creatinine	10-20	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
16845226-7	2006	We have found that during incremental exercise at the power output between 30-120 W, performed at 60 rev.min(-1), oxygen uptake in the group H was significantly greater than in the group L (ANCOVA, p=0.003, upward shift of the intercept in VO2/power output relationship).	Oxygen	114-120	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
16845226-8	2006	During cycling at the same power output but at 120 rev.min(-1), the oxygen uptake was also higher in the group H, when compared to the group L (i.e. upward shift of the intercept in VO2/power output relationship, ANCOVA, p=0.002).	Oxygen	68-74	CD59 molecule (CD59 blood group)	Homo sapiens	55-61
16845226-9	2006	Moreover, the increase in pedalling rate from 60 to 120 rev.min(-1) was accompanied by a significantly higher increase of oxygen cost of cycling and by a significantly higher plasma lactate concentration in subjects from group H. We concluded that the muscle mechanical efficiency, expressed by the VO2/PO ratio, during cycling in the range of power outputs 30-120 W, performed at 60 as well as 120 rev.min(-1), is significantly lower in the individuals with the highest content of MyHC II, when compared to the individuals with the lowest content of MyHC II in the vastus lateralis.	Oxygen	122-128	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
16845226-9	2006	Moreover, the increase in pedalling rate from 60 to 120 rev.min(-1) was accompanied by a significantly higher increase of oxygen cost of cycling and by a significantly higher plasma lactate concentration in subjects from group H. We concluded that the muscle mechanical efficiency, expressed by the VO2/PO ratio, during cycling in the range of power outputs 30-120 W, performed at 60 as well as 120 rev.min(-1), is significantly lower in the individuals with the highest content of MyHC II, when compared to the individuals with the lowest content of MyHC II in the vastus lateralis.	Lactic Acid	182-189	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
17048623-3	2006	A mixture of water-acetonitrile-sodium dodecyl sulfate-phosphorous acid (650:350:5:1) was used as the mobile phase at flow rate of 1.5 mL x min(-1).	Water	13-18	CD59 molecule (CD59 blood group)	Homo sapiens	140-146
16426790-6	2006	The mobile phase was methanol-water-glacial acetic acid (10:89.96:0.04 v/v/v, pH 3.5) delivered to the column at 1 ml min-1 and the column temperature was maintained at 30 degrees C. Galactosamine hydrochloride (Gal-HCl) was used as an internal standard.	Methanol	21-29	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
16426790-6	2006	The mobile phase was methanol-water-glacial acetic acid (10:89.96:0.04 v/v/v, pH 3.5) delivered to the column at 1 ml min-1 and the column temperature was maintained at 30 degrees C. Galactosamine hydrochloride (Gal-HCl) was used as an internal standard.	Acetic Acid	44-55	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
16640832-7	2006	For example, the CL(hep, in-vivo) of mibefradil in donor GNG was 4.27 mL min(-1) kg(-1) in the presence of serum and 0.46 mL min(-1) kg(-1) in the absence of serum (4.88 mL min(-1) kg(-1) observed in-vivo).	epolamine	20-23	CD59 molecule (CD59 blood group)	Homo sapiens	73-79
16640832-7	2006	For example, the CL(hep, in-vivo) of mibefradil in donor GNG was 4.27 mL min(-1) kg(-1) in the presence of serum and 0.46 mL min(-1) kg(-1) in the absence of serum (4.88 mL min(-1) kg(-1) observed in-vivo).	Mibefradil	37-47	CD59 molecule (CD59 blood group)	Homo sapiens	73-79
16640832-7	2006	For example, the CL(hep, in-vivo) of mibefradil in donor GNG was 4.27 mL min(-1) kg(-1) in the presence of serum and 0.46 mL min(-1) kg(-1) in the absence of serum (4.88 mL min(-1) kg(-1) observed in-vivo).	Mibefradil	37-47	CD59 molecule (CD59 blood group)	Homo sapiens	125-131
16640832-7	2006	For example, the CL(hep, in-vivo) of mibefradil in donor GNG was 4.27 mL min(-1) kg(-1) in the presence of serum and 0.46 mL min(-1) kg(-1) in the absence of serum (4.88 mL min(-1) kg(-1) observed in-vivo).	Mibefradil	37-47	CD59 molecule (CD59 blood group)	Homo sapiens	125-131
16715917-7	2006	Blood pressure finally returned towards baseline after infusion of norepinephrine 0.2 microg x kg(-1) x min(-1) and epinephrine 0.1 microg x kg(-1) x min(-1).	Norepinephrine	67-81	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
16518628-3	2006	Such a kinetic model is available for neonates undergoing continuous ECRT (CECRT) with a leucine clearance>or=35 ml min-1 1.73 m-2.	cecrt	75-80	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
16518628-3	2006	Such a kinetic model is available for neonates undergoing continuous ECRT (CECRT) with a leucine clearance>or=35 ml min-1 1.73 m-2.	Leucine	89-96	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
16518628-9	2006	A leucine clearance>or=50 ml min-1 1.73 m-2 is required to obtain a kinetic model similar to that reported in neonates, both with CECRT and HDi.	cecrt	133-138	CD59 molecule (CD59 blood group)	Homo sapiens	32-37
16677358-9	2006	The mean creatinine clearance was 96+/-24 mL/min/1.73 m2 at steroid withdrawal and 93+/-20 mL/min/1.73 m2 at the latest follow-up.	Creatinine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
16598851-8	2006	Calculated fat oxidation was lower during the glucose trial (0.17 +/- 0.02 vs. 0.25 +/- 0.03 g min-1, P < 0.001).	Glucose	46-53	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
16598851-9	2006	Activation of alpha2-AMPK was attenuated in the glucose trial compared to the placebo trial (0.24 +/- 0.07 vs. 0.46 +/- 0.14 pmol mg-1 min-1, P = 0.03), whereas the alpha1-AMPK activity was not different between trials or affected by exercise.	Glucose	48-55	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
16552438-3	2006	Patients with creatinine clearance 30-50 ml min(-1) received a reduced dose of capecitabine (750 mg m(-2) twice daily).	Creatinine	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	44-50
16585616-7	2006	It should be noted that the average value of dissolved oxygen was 3.4 mg L-1 with an air supply of 15 L min-1, and there was no indication of oxygen limitation.	Oxygen	55-61	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
16551899-8	2006	Postoperatively, milrinone clearance was significantly impaired (0.4 mL x kg(-1) x min(-1)), improved by the 12th postoperative hour, and approached steady-state clearance (2.6 mL x kg(-1) x min(-1)) by postoperative day 4.	Milrinone	17-26	CD59 molecule (CD59 blood group)	Homo sapiens	83-89
16551899-8	2006	Postoperatively, milrinone clearance was significantly impaired (0.4 mL x kg(-1) x min(-1)), improved by the 12th postoperative hour, and approached steady-state clearance (2.6 mL x kg(-1) x min(-1)) by postoperative day 4.	Milrinone	17-26	CD59 molecule (CD59 blood group)	Homo sapiens	191-197
26558584-4	2006	The production rate of carbon nanostructures including CNTs at 75 A is as high as 5.89 +- 0.28 g min(-1).	Carbon	23-29	CD59 molecule (CD59 blood group)	Homo sapiens	97-103
16376465-4	2006	We constructed a glycolipid-anchored hIL-12 (GPI-hIL-12) by fusing the coding region of p35 and p40 subunits of hIL-12 with the GPI-signal sequence of CD59 at the C-terminal ends.	Glycolipids	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	151-155
16381663-7	2006	Enzymatic efficiencies calculated as kcat/Km were more than 100 mM-1 min-1 for dolasetron and 1.3, 0.43, and 0.47 mM-1 min-1 for daunorubicin, oracin, and NNK, respectively.	dolasetron	79-89	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
16381663-7	2006	Enzymatic efficiencies calculated as kcat/Km were more than 100 mM-1 min-1 for dolasetron and 1.3, 0.43, and 0.47 mM-1 min-1 for daunorubicin, oracin, and NNK, respectively.	Daunorubicin	129-141	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
16381663-7	2006	Enzymatic efficiencies calculated as kcat/Km were more than 100 mM-1 min-1 for dolasetron and 1.3, 0.43, and 0.47 mM-1 min-1 for daunorubicin, oracin, and NNK, respectively.	Daunorubicin	129-141	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
16381663-7	2006	Enzymatic efficiencies calculated as kcat/Km were more than 100 mM-1 min-1 for dolasetron and 1.3, 0.43, and 0.47 mM-1 min-1 for daunorubicin, oracin, and NNK, respectively.	oracine	143-149	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
16381663-7	2006	Enzymatic efficiencies calculated as kcat/Km were more than 100 mM-1 min-1 for dolasetron and 1.3, 0.43, and 0.47 mM-1 min-1 for daunorubicin, oracin, and NNK, respectively.	oracine	143-149	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
16381663-9	2006	In addition to its reducing activity, AKR1B10 catalyzed the NADP+-dependent oxidation of the secondary alcohol (S)-1-indanol to 1-indanone with high enzymatic efficiency (kcat/Km=112 mM-1 min-1).	NADP	60-65	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
16381663-9	2006	In addition to its reducing activity, AKR1B10 catalyzed the NADP+-dependent oxidation of the secondary alcohol (S)-1-indanol to 1-indanone with high enzymatic efficiency (kcat/Km=112 mM-1 min-1).	1-indanol	111-124	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
16381663-9	2006	In addition to its reducing activity, AKR1B10 catalyzed the NADP+-dependent oxidation of the secondary alcohol (S)-1-indanol to 1-indanone with high enzymatic efficiency (kcat/Km=112 mM-1 min-1).	indacrinone	128-138	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
16328190-8	2006	We conclude that MLSS(workload) and MLSS(intensity) are dependent on pedal cadence (50 vs. 100 rev min(-1)) in recreationally active individuals.	mlss	17-21	CD59 molecule (CD59 blood group)	Homo sapiens	99-105
16328190-8	2006	We conclude that MLSS(workload) and MLSS(intensity) are dependent on pedal cadence (50 vs. 100 rev min(-1)) in recreationally active individuals.	mlss	36-40	CD59 molecule (CD59 blood group)	Homo sapiens	99-105
16493049-0	2006	Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity.	Glycosylphosphatidylinositols	14-42	CD59 molecule (CD59 blood group)	Homo sapiens	52-56
16493049-9	2006	To investigate mechanisms, we compared the signaling capacity of the various forms of expressed and incorporated CD59 following Ab cross-linking in calcium flux assays.	Calcium	148-155	CD59 molecule (CD59 blood group)	Homo sapiens	113-117
16493049-10	2006	GPI-anchored CD59, with or without glycosylation, mediated activation events, whereas CD59 forms lacking the GPI anchor did not.	Glycosylphosphatidylinositols	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	13-17
16493049-11	2006	The data show that the increased susceptibility of target cells expressing CD59 to NK cytotoxicity requires GPI anchor-mediating signaling events, likely mediated by interactions between GPI-anchored CD59 on targets and NK receptors.	Glycosylphosphatidylinositols	108-111	CD59 molecule (CD59 blood group)	Homo sapiens	75-79
16493049-11	2006	The data show that the increased susceptibility of target cells expressing CD59 to NK cytotoxicity requires GPI anchor-mediating signaling events, likely mediated by interactions between GPI-anchored CD59 on targets and NK receptors.	Glycosylphosphatidylinositols	108-111	CD59 molecule (CD59 blood group)	Homo sapiens	200-204
16540826-6	2006	RESULTS: Peak oxygen uptake increased significantly in the diet and exercise group (mean +/- SD: 32 +/- 5 mL x kg(-1) x min(-1) before; 40 +/- 8 mL x kg(-1) x min(-1) after) but not in the diet only group (34 +/- 7 mL x kg(-1) x min(-1) before; 35 +/- 8 mL x kg(-1) x min(-1) after).	Oxygen	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	120-126
16550155-9	2006	Dobutamine is recommended when the cardiac index is less than 2.5 L x min(-1) x m(-2).	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	70-76
16489052-5	2006	We have previously observed a decrease of CD59 in camptothecin-induced apoptotic IMR32 cells, whereas expression was increased in the surviving fraction compared with untreated cells.	Camptothecin	50-62	CD59 molecule (CD59 blood group)	Homo sapiens	42-46
16458147-6	2006	RESULTS: In a first group of 11 patients, a significant increase in renal artery average peak velocity (APV) was observed after intrarenal (IR) bolus injection of 600 microg isosorbide dinitrate (41 +/- 19%), 30 mg papaverine (50 +/- 34%), 50 microg dopamine (94 +/- 54%), 0.8 microg x kg(-1) fenoldopam (80 +/- 25%), and during IR infusion of 1 microg x kg(-1) x min(-1) fenoldopam (86 +/- 28%).	Isosorbide Dinitrate	174-194	CD59 molecule (CD59 blood group)	Homo sapiens	364-370
16458147-8	2006	The 3 and 5 microg x kg(-1) x min(-1) of dopamine modestly reduced renal resistance index (RI) (-13 +/- 15% and -25 +/- 20%, respectively).	Dopamine	41-49	CD59 molecule (CD59 blood group)	Homo sapiens	30-36
16311277-6	2006	RESULTS: Magnesium groups required significantly less propofol [mean (sd) 121.5 (13.3), 102.2 (8.0) and 101.3 (9.7) microg kg(-1) min(-1) respectively] than the control group (140.7 (16.5) microg kg(-1) min(-1)).	Magnesium	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	130-136
16311277-6	2006	RESULTS: Magnesium groups required significantly less propofol [mean (sd) 121.5 (13.3), 102.2 (8.0) and 101.3 (9.7) microg kg(-1) min(-1) respectively] than the control group (140.7 (16.5) microg kg(-1) min(-1)).	Magnesium	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	203-209
16433871-8	2006	CL(Cr) ranged from 9 to 172 ml min(-1) and changes varied from -76 to 58 ml min(-1) (gentamicin) and -86 to 93 ml min(-1) (vancomycin).	Chromium	3-5	CD59 molecule (CD59 blood group)	Homo sapiens	31-37
16424718-11	2006	At day 4, insulin-mediated glucose disposal was higher in group AG (2.4 +/- 0.7 mg x kg(-1) x min(-1) glucose), with significant difference from group C (1.9 +/- 0.6 mg x kg(-1) x min(-1), p = .044).	Glucose	102-109	CD59 molecule (CD59 blood group)	Homo sapiens	94-100
16424718-12	2006	At day 8, glucose disposal was higher in group AG (2.2 +/- 0.7 mg x kg(-1) x min(-1) glucose), with significant difference in comparison with group C (1.2 +/- 0.6, p < .001).	Glucose	10-17	CD59 molecule (CD59 blood group)	Homo sapiens	77-83
16424718-12	2006	At day 8, glucose disposal was higher in group AG (2.2 +/- 0.7 mg x kg(-1) x min(-1) glucose), with significant difference in comparison with group C (1.2 +/- 0.6, p < .001).	Glucose	85-92	CD59 molecule (CD59 blood group)	Homo sapiens	77-83
16826899-3	2006	In the present paper, thermal decomposition of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) heated with 5 degrees C x min(-1) was investigated by in-situ FTIR spectroscopy.	octogen	47-95	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
16826899-3	2006	In the present paper, thermal decomposition of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) heated with 5 degrees C x min(-1) was investigated by in-situ FTIR spectroscopy.	octogen	97-100	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
16826922-5	2006	The input power, carrier gas flow and assistant gas flow for Al are 1 150 W, 0.6 and 1.0 L x min(-1), respectively.	Aluminum	61-63	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
16423629-10	2006	The IVGTT data revealed that insulin sensitivity (7.3 +/- 0.6 mU x L-1 x min-1) and glucose effectiveness (0.024 +/- 0.002 min-1) were not changed after the crossing.	Glucose	84-91	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
16553341-3	2006	All received an infusion of remifentanil at a dose of 0.5 microg x Kg(-1) x min(-1) until tracheal intubation and then 0.25 microg x Kg(-1) x min(-1) during surgery.	Remifentanil	28-40	CD59 molecule (CD59 blood group)	Homo sapiens	76-82
16491901-6	2006	Anesthesia was maintained with 2-3% sevoflurane in 1 l x min(-1) of oxygen and 2 l x min(-1) of nitrous oxide.	Nitrous Oxide	96-109	CD59 molecule (CD59 blood group)	Homo sapiens	85-91
17080916-1	2006	CD55 and CD59 are glycophosphatidylinositol-anchored proteins with complement inhibitory properties.	glycophosphatidylinositol	18-43	CD59 molecule (CD59 blood group)	Homo sapiens	9-13
16424800-3	2006	Therefore, we quantified the hemodynamic response to infusion of adrenaline (0.04, 0.06, and 0.08 microg x kg(-1) x min(-1) for 20 minutes each) in 8 healthy men and 8 healthy premenopausal women.	Epinephrine	65-75	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
16271846-5	2005	By using cationic liposome (Lipfectamine-2000)-mediated transfection method, the recombinant plasmid pALTER-MAX-CD59 and the selective marker PcDNA were cotransfected into Hela cells and normal Chinese hamster ovary (CHO) cells.	lipfectamine-2000	28-45	CD59 molecule (CD59 blood group)	Homo sapiens	112-116
16534238-8	2006	Creatinine clearance increased from 20 +/- 15 ml/min/1.73 m2 at the start of tacrolimus therapy to 37 +/- 29 ml/min/1.73 m2 and to 32 +/- 26 ml/min/1.73 m2 after 5 and 7 years.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
16534238-8	2006	Creatinine clearance increased from 20 +/- 15 ml/min/1.73 m2 at the start of tacrolimus therapy to 37 +/- 29 ml/min/1.73 m2 and to 32 +/- 26 ml/min/1.73 m2 after 5 and 7 years.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
16534238-8	2006	Creatinine clearance increased from 20 +/- 15 ml/min/1.73 m2 at the start of tacrolimus therapy to 37 +/- 29 ml/min/1.73 m2 and to 32 +/- 26 ml/min/1.73 m2 after 5 and 7 years.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
16534238-8	2006	Creatinine clearance increased from 20 +/- 15 ml/min/1.73 m2 at the start of tacrolimus therapy to 37 +/- 29 ml/min/1.73 m2 and to 32 +/- 26 ml/min/1.73 m2 after 5 and 7 years.	Tacrolimus	77-87	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
16837818-10	2006	The levels of E-DAF and E-CD59 were significantly lower in the DMN group than non-DMN group (DAF, p < 0.01; CD59, p < 0.0001).	Dimethylnitrosamine	63-66	CD59 molecule (CD59 blood group)	Homo sapiens	26-30
16837818-10	2006	The levels of E-DAF and E-CD59 were significantly lower in the DMN group than non-DMN group (DAF, p < 0.01; CD59, p < 0.0001).	Dimethylnitrosamine	63-66	CD59 molecule (CD59 blood group)	Homo sapiens	111-115
16409531-2	2006	A bolus of 0.1 mg intravenous atropine resulted in tachycardia of up to 180-220 b x min(-1), which persisted for 35 min.	Atropine	30-38	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
16470517-4	2006	min(-1) was found to be the optimal sheath liquid to promote successful ionization of the amitrole.	Amitrole	90-98	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
16581924-2	2006	Three TL glow peaks for the Tb4O7 doped sample appeared in the temperature regions of about (1) 347-353 K, (2) 378-383 K and (3) 453-458 K, when heated at a rate of 20 K min(-1) after UV or X-ray irradiation at room temperature.	tb4o7	28-33	CD59 molecule (CD59 blood group)	Homo sapiens	170-176
16373281-8	2006	Splanchnic oxygen uptake showed a significant peak increase of 1.40 (0.44-4.13) mmol x min(-1) from a baseline level of 2.18 (1.41-3.31) mmol x min(-1).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
16373281-8	2006	Splanchnic oxygen uptake showed a significant peak increase of 1.40 (0.44-4.13) mmol x min(-1) from a baseline level of 2.18 (1.41-3.31) mmol x min(-1).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	144-150
16901850-5	2006	Transabdominal Doppler ultrasound was used to evaluate the effects of either a standard meal or intravenous infusion of serotonin (2.5-20 nmol kg-1 min-1) on the superior mesenteric artery resistance index, platelet-depleted plasma levels of serotonin, blood pressure, heart rate and electrocardiogram.	Serotonin	120-129	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
16179040-5	2005	Preoperative median [range] cardiac output was 3.85 [2.2-6.0] l.min(-1) for bolus thermodilution cardiac output and 4.2 [2.0-7.2] l.min(-1) for pulse dye densitometry using indocyanine green 20 mg.	Indocyanine Green	173-190	CD59 molecule (CD59 blood group)	Homo sapiens	64-70
16094632-6	2005	The membrane was demonstrated to resist physiological transmural pressure (burst pressure resistance >500 mm Hg) and presented a high-water permeation resistance (1 mL/cm(2) min(-1) at 120 mmHg).	Water	137-142	CD59 molecule (CD59 blood group)	Homo sapiens	177-183
16316362-5	2005	Compared to those in the IV iron group, patients in the oral iron treatment group showed a greater decline in GFR during the study (-4.40 vs. -1.45 mL/min/1.73m2, P= 0.0100).	Iron	61-65	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
16563273-0	2005	[The effect of atorvastatin on the expression of CD55, CD59 in patients with hyperlipidemia].	Atorvastatin	15-27	CD59 molecule (CD59 blood group)	Homo sapiens	55-59
16563273-8	2005	After atorvastatin therapy, the MFIs of CD59 positive lymphocytes, monocytes and granulocytes increased (4.34 +/- 1.16 vs 3.69 +/- 0.76, 4.52 +/- 1.36 vs 3.91 +/- 0.89, 5.67 +/- 1.72 vs 4.56 +/- 1.03, P < 0.05, < 0.05 and < 0.01 respectively), which were not correlated with changes of blood lipids.	Atorvastatin	6-18	CD59 molecule (CD59 blood group)	Homo sapiens	40-44
16563273-10	2005	The expression of CD55 is related with complement activation; The expression of CD59 is up-regulated after atorvastatin treatment independently of blood lipids.	Atorvastatin	107-119	CD59 molecule (CD59 blood group)	Homo sapiens	80-84
16179347-3	2005	Circulating, aged cells showed colocalization of Fas with the raft marker proteins Galpha(s) and CD59; the existence of Fas-associated FasL, FADD and caspase 8; and caspase 8 and caspase 3 activity.	ammonium ferrous sulfate	49-52	CD59 molecule (CD59 blood group)	Homo sapiens	97-101
16267597-2	2005	Fluorescence melting experiments show that this intramolecular quadruplex, which is more stable in potassium- than sodium-containing buffers, shows considerable hysteresis between the melting and annealing profiles, even when heated at a rate of 0.05 degrees C min(-1).	Potassium	99-108	CD59 molecule (CD59 blood group)	Homo sapiens	261-267
16267597-2	2005	Fluorescence melting experiments show that this intramolecular quadruplex, which is more stable in potassium- than sodium-containing buffers, shows considerable hysteresis between the melting and annealing profiles, even when heated at a rate of 0.05 degrees C min(-1).	Sodium	115-121	CD59 molecule (CD59 blood group)	Homo sapiens	261-267
16253720-7	2005	For the entire group, the estimated mean difference in glomerular filtration rates between the cholestyramine and placebo groups was 0.39 mL/min/1.73 m2 (0.007 mL/s/1.73 m2; P = 0.28) during a follow-up period of more than 8 years.	Cholestyramine Resin	95-109	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
16199414-8	2005	An infusion of remifentanil at the rate of 0.15 microg kg(-1) min(-1) was started, sevoflurane continued at 0.6 MAC and cisatracurium 0.2 mg kg(-1) was given.	Remifentanil	15-27	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
16199414-10	2005	RESULTS: Baseline HR [mean (SD)] of 117 (20) beats min(-1) decreased significantly from 12.5 min onwards after starting the remifentanil infusion in the control group [106 (18) at 12.5 min and 99 (16) beats min(-1) at 45 min].	Remifentanil	124-136	CD59 molecule (CD59 blood group)	Homo sapiens	51-57
16179040-5	2005	Preoperative median [range] cardiac output was 3.85 [2.2-6.0] l.min(-1) for bolus thermodilution cardiac output and 4.2 [2.0-7.2] l.min(-1) for pulse dye densitometry using indocyanine green 20 mg.	Indocyanine Green	173-190	CD59 molecule (CD59 blood group)	Homo sapiens	132-138
16211731-4	2005	Remifentanil was given to all patients at a constant infusion rate of 0.3 microg kg [-1] min[-1] throughout anaesthesia.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
16131098-4	2005	The conversion efficiency of phosphatidyl choline to choline was 50% at 0.2 mL min(-1).	Phosphatidylcholines	29-49	CD59 molecule (CD59 blood group)	Homo sapiens	79-85
16131098-4	2005	The conversion efficiency of phosphatidyl choline to choline was 50% at 0.2 mL min(-1).	Choline	42-49	CD59 molecule (CD59 blood group)	Homo sapiens	79-85
16167789-4	2005	In the latter group, PGE1 was administered intravenously at a rate of 0.05 microg x kg(-1) x min(-1) during surgery.	Alprostadil	21-25	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
16240034-2	2005	DSC scans of glassy water prepared at 140 K exhibit on heating an endothermic step assignable to glass --> liquid transition, with an onset temperature (T(g)) of 136 +/- 2 K on heating at 30 K min(-1).	Water	20-25	CD59 molecule (CD59 blood group)	Homo sapiens	196-202
16132130-3	2005	The rejection parameter q (RPq) of the DRC and the flow rate of ammonia (NH3) were optimized and set at 0.7 and 0.6 mL min(-1), respectively.	Ammonia	73-76	CD59 molecule (CD59 blood group)	Homo sapiens	119-125
15907827-10	2005	CONCLUSION: The decreased GPI-PLD expression may reduce the release of GPI-anchored CD55 and CD59 in leukemia cells and finally decrease complement mediated killing of these cells in chronic phase of CML.	Glycosylphosphatidylinositols	26-29	CD59 molecule (CD59 blood group)	Homo sapiens	93-97
16195986-4	2005	Absolute maximal oxygen uptake was significantly higher in elite than junior players (4.8 vs. 4.2 L x min(-1), p < 0.01), but relative expressions, including allometric scaling, eliminated the difference.	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
16103515-2	2005	We randomly allocated 14 patients to receive intravenous glucose at 2 mg x kg(-1) x min(-1) (glucose group) starting with the surgical incision or an equivalent amount of normal saline 0.9% (control group).	Glucose	57-64	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
15936165-4	2005	The cobalt released by passage of a 5 x 10(-4) mol l(-1) sulphuric acid stream at a flow-rate of 2.3 ml min(-1) is merged with a volume of 314 microl of sample containing penicillamine in ammonium-ammonia buffer at pH 9.5 to measure the absorbance at 360 nm.	Cobalt	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
16167790-9	2005	When the atropine 40 microg x kg(-1) was administered, heart rate increased > 20 beats x min(-1) in all patients of the control group, but 62.5% of patients in the clonidine group (P< 0.05).	Atropine	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
16167799-7	2005	Atropine 0.5 mg was given intravenously and heart rate increased to 50 beats x min(-1).	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	79-85
16167799-8	2005	Additionally atropine 0.25 mg increased heart rate to 70 beats x min(-1).	Atropine	13-21	CD59 molecule (CD59 blood group)	Homo sapiens	65-71
16037145-11	2005	We studied remifentanil as a sole drug for ESWL and have shown that an infusion rate of 0.05 microg x kg-1 x min-1 plus patient-controlled analgesia demands of 10 microg provides adequate analgesia and has significantly less side effects than a dose of 0.1 microg x kg-1 x min-1 plus 10 microg demands.	Remifentanil	11-23	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
16112041-8	2005	Conversely, the underestimation by means of the CG formula found in lean people (-13.0 mL/min/1.73 m2 [-0.22 mL/s/1.73 m2]) was blunted in overweight people (BMI, 25 to 30 kg/m2) and reversed to overestimation (+10.1 mL/min/1.73 m2 [+0.17 mL/s/1.73 m2]) in obese subjects (BMI > 30 kg/m2).	cg	48-50	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
16112041-8	2005	Conversely, the underestimation by means of the CG formula found in lean people (-13.0 mL/min/1.73 m2 [-0.22 mL/s/1.73 m2]) was blunted in overweight people (BMI, 25 to 30 kg/m2) and reversed to overestimation (+10.1 mL/min/1.73 m2 [+0.17 mL/s/1.73 m2]) in obese subjects (BMI > 30 kg/m2).	cg	48-50	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
16037145-11	2005	We studied remifentanil as a sole drug for ESWL and have shown that an infusion rate of 0.05 microg x kg-1 x min-1 plus patient-controlled analgesia demands of 10 microg provides adequate analgesia and has significantly less side effects than a dose of 0.1 microg x kg-1 x min-1 plus 10 microg demands.	Remifentanil	11-23	CD59 molecule (CD59 blood group)	Homo sapiens	273-278
16052121-6	2005	RESULTS: The average (+/- sd) remifentanil dose was 0.035 +/- 0.012 microg x kg x min(-1).	Remifentanil	30-42	CD59 molecule (CD59 blood group)	Homo sapiens	82-88
15863438-11	2005	CONCLUSIONS: In adult patients allowed to breathe normally, prompt and consistent inhalation induction of anaesthesia with sevoflurane is obtained when fresh gas flow is limited to 6 litre min(-1) from a Mapleson D circuit, but smaller flows are impractical.	Sevoflurane	123-134	CD59 molecule (CD59 blood group)	Homo sapiens	189-196
16450015-5	2005	The reference interval for serum creatinine concentration includes up to 25% of people (particularly thin, elderly women) who have an estimated glomerular filtration rate (eGFR) that is significantly reduced (< 60 mL/min/1.73 m).	Creatinine	33-43	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
15942765-10	2005	Analysis of EPOC data revealed that CT resulted in a significantly higher (p<0.05) oxygen uptake during the first 30 min of recovery (0.27 +/- 0.01 l min(-1) vs 0.23+/-0.01 l min(-1)); though, at 60 min, treatment differences were not present.	Oxygen	86-92	CD59 molecule (CD59 blood group)	Homo sapiens	153-159
16091585-5	2005	As expected, caveolin and GPI-bound proteins CD55, CD59 and GPI-bound form of CD58 were preferentially localized in detergent-resistant membrane domains (DRMs).	Glycosylphosphatidylinositols	26-29	CD59 molecule (CD59 blood group)	Homo sapiens	51-55
15955567-2	2005	In the present work we measured beta-adrenergic receptor number and affinity in bone marrow committed monocyte progenitor cells (CD59(+)) following BI/S.	Bismuth	148-150	CD59 molecule (CD59 blood group)	Homo sapiens	129-133
15955567-4	2005	CD14 expression in macrophages derived in vitro from CD59(+) cells following BI/S was significantly increased by epinephrine and this change was blocked by beta(2)-adrenergic receptor antagonist.	Bismuth	77-79	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
15955567-4	2005	CD14 expression in macrophages derived in vitro from CD59(+) cells following BI/S was significantly increased by epinephrine and this change was blocked by beta(2)-adrenergic receptor antagonist.	Sulfur	80-81	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
15955567-4	2005	CD14 expression in macrophages derived in vitro from CD59(+) cells following BI/S was significantly increased by epinephrine and this change was blocked by beta(2)-adrenergic receptor antagonist.	Epinephrine	113-124	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
16053416-5	2005	The reference interval for serum creatinine concentration includes up to 25% of people (particularly thin, elderly women) who have an estimated glomerular filtration rate (eGFR) that is significantly reduced (< 60 mL/min/1.73 m2).	Creatinine	33-43	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
16189600-3	2005	During the isomerization of n-butane (1% in He, 80 ml min-1, 0.5 g catalyst at 333 K), the average Mn valence did not change further.	butane	28-36	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
15967288-2	2005	The chromatographic separation was successfully achieved on the Discovery Zr-PS column (150 mm x 4.6 mm i.d., 5 microm), using a mobile phase methanol-phosphate buffer (pH 4.5; 0.05 M)-tetrahydrofurane (21:74:5, v/v/v) and the flow rate 0.5 ml min(-1).	tetrahydrofuran	185-201	CD59 molecule (CD59 blood group)	Homo sapiens	244-250
16037150-3	2005	Preoperatively, each patient received a fentanyl infusion of 2 microg x kg(-1) x min(-1) until the respiratory rate was <5 breaths/min.	Fentanyl	40-48	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
15940452-6	2005	With an SE-30/DBA-coated denuder operating within an airflow range of 100-500 mL min(-1), the phase separation was shown to be consistent with theoretical predictions derived by use of the Gormley-Kennedy equation.	Silicone Elastomers	8-13	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
15940452-6	2005	With an SE-30/DBA-coated denuder operating within an airflow range of 100-500 mL min(-1), the phase separation was shown to be consistent with theoretical predictions derived by use of the Gormley-Kennedy equation.	dibutylamine	14-17	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
15970963-6	2005	A semi-quantitative, absolute detection limit of 17 nmol s(-1) was obtained for sodium with a sample flow rate of 100 microL min(-1) and an integration time of 100 ms in air at atmospheric pressure.	Sodium	80-86	CD59 molecule (CD59 blood group)	Homo sapiens	125-131
15817446-4	2005	Remarkably, however, antibody-mediated cross-linking of either dipalmitoyl- or dilinoleoyl-PE-PEG-anchored streptavidin conjugates in Jurkat cells induced elevation of cytoplasmic calcium levels and tyrosine phosphorylation of the scaf-folding protein linker of T-cell activation in a manner similar to that observed upon cross-linking of endogenous CD59 or ganglioside GM1.	dilinoleoyl-pe-peg	79-97	CD59 molecule (CD59 blood group)	Homo sapiens	350-354
15817446-6	2005	Confocal fluorescence microscopy revealed that PE-PEG-streptavidin conjugates with saturated versus polyunsaturated anchors showed very similar surface distributions vis a vis GM1 or CD59 under conditions where one or both species were cross-linked.	pe	47-49	CD59 molecule (CD59 blood group)	Homo sapiens	183-187
15817446-6	2005	Confocal fluorescence microscopy revealed that PE-PEG-streptavidin conjugates with saturated versus polyunsaturated anchors showed very similar surface distributions vis a vis GM1 or CD59 under conditions where one or both species were cross-linked.	Polyethylene Glycols	50-53	CD59 molecule (CD59 blood group)	Homo sapiens	183-187
15917509-3	2005	The apparent Km for ribavirin is 540 microM, and k(cat) is 1.8 min-1.	Ribavirin	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
15917509-8	2005	In phosphate-buffered saline plus ATP and 2,3-bisphosphoglycerate, the apparent Km for ribavirin is 88 microM, and k(cat) is 4.0 min-1.	Phosphate-Buffered Saline	3-28	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
15967908-3	2005	min(-1) of dextrose intravenously will (1) have more pronounced suppression of endogenous glucose production, leading to (2) a greater reduction in whole-body protein breakdown.	Glucose	11-19	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
15967908-3	2005	min(-1) of dextrose intravenously will (1) have more pronounced suppression of endogenous glucose production, leading to (2) a greater reduction in whole-body protein breakdown.	Glucose	90-97	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
15917509-8	2005	In phosphate-buffered saline plus ATP and 2,3-bisphosphoglycerate, the apparent Km for ribavirin is 88 microM, and k(cat) is 4.0 min-1.	Adenosine Triphosphate	34-37	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
15917509-8	2005	In phosphate-buffered saline plus ATP and 2,3-bisphosphoglycerate, the apparent Km for ribavirin is 88 microM, and k(cat) is 4.0 min-1.	2,3-Diphosphoglycerate	42-65	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
15917509-8	2005	In phosphate-buffered saline plus ATP and 2,3-bisphosphoglycerate, the apparent Km for ribavirin is 88 microM, and k(cat) is 4.0 min-1.	Ribavirin	87-96	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
15815939-4	2005	The blood lactate concentration at sub-maximal running speed (425 m min(-1)) was significantly greater in H than in N (paired t-test: P<0.05).	Lactic Acid	10-17	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
15955377-5	2005	The glucose disposal rate (M-value) was considerably lower in patients (2.4+/-1.6 mg kg-1 min-1, 0.2-8.1) compared with healthy subjects (7.1+/-0.2 mg kg-1 min-1, p<0.01).	Glucose	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
15955377-5	2005	The glucose disposal rate (M-value) was considerably lower in patients (2.4+/-1.6 mg kg-1 min-1, 0.2-8.1) compared with healthy subjects (7.1+/-0.2 mg kg-1 min-1, p<0.01).	Glucose	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
15855310-6	2005	Mean muscle glycogen synthesis as measured by the isotope method was 115 +/- 26 micromol x kg(-1) muscle x min(-1) vs. 178 +/- 72 micromol x kg(-1) muscle x min(-1) (P = 0.03) measured by MRS. Glycogen synthesis rates measured by MRS exceeded 100% of glucose uptake in three of the six subjects.	Glycogen	12-20	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
16195006-2	2005	The average oxygen uptake for international soccer teams ranges from 55 to 68 ml.kg-1.min-1 and the half-squat maximal strength from 120 to 180 kg.	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
15966380-3	2005	METHODS: Propranolol (n=22) or esmolol (n= 29) was given intravenously when the heart rate was above 100 beats x min(-1) during emergence from anesthesia.	Propranolol	9-20	CD59 molecule (CD59 blood group)	Homo sapiens	113-119
15966380-3	2005	METHODS: Propranolol (n=22) or esmolol (n= 29) was given intravenously when the heart rate was above 100 beats x min(-1) during emergence from anesthesia.	esmolol	31-38	CD59 molecule (CD59 blood group)	Homo sapiens	113-119
15966380-5	2005	RESULTS: The total dose of propranolol was 0.52+/-0.21 mg (mean+/-SD), which decreased the heart rate significantly from 109.2 +/- 19.0 to 89.2 +/-11.8 beats x min(-1).	Propranolol	27-38	CD59 molecule (CD59 blood group)	Homo sapiens	160-166
15966380-6	2005	The total dose of esmolol was 32.8 +/- 16.2 mg, which decreased the heart rate significantly from 110.0+/-13.9 to 84.9+/-10.7 beats x min(-1).	esmolol	18-25	CD59 molecule (CD59 blood group)	Homo sapiens	134-140
15845659-26	2005	min(-1) was reached after 4 h. The combination of remifentanil with a nonsteroidal antiinflammatory drug provided adequate analgesia in 73% of patients 30 min after tracheal extubation.	Remifentanil	50-62	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
15870622-12	2005	Indomethacin (-2.43 +/- 0.95 mL x min(-1), P < 0.007) and celecoxib (-3.88 +/- 0.94 mL x min(-1), P < 0.0001) significantly reduced free water clearance compared with placebo during recovery.	Indomethacin	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	34-40
15877168-5	2005	Denuder/filter sampling of the 4,4"-MDI aerosol at 500 ml min(-1) yielded a phase distribution that was in accordance with the results from the reference method.	4,4'-diphenylmethane diisocyanate	31-39	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
15593236-2	2005	The catalyst obtained catalysed the transesterification process between p-nitrophenyl acetate and hexanol with maximal initial velocity(nu(max)) of 4.73 +/- 0.47 microM min(-1) mg(-1), and turnover rate (k(cat)) of 8.67 min(-1).	4-nitrophenyl acetate	72-93	CD59 molecule (CD59 blood group)	Homo sapiens	169-175
15593236-2	2005	The catalyst obtained catalysed the transesterification process between p-nitrophenyl acetate and hexanol with maximal initial velocity(nu(max)) of 4.73 +/- 0.47 microM min(-1) mg(-1), and turnover rate (k(cat)) of 8.67 min(-1).	4-nitrophenyl acetate	72-93	CD59 molecule (CD59 blood group)	Homo sapiens	220-226
15593236-2	2005	The catalyst obtained catalysed the transesterification process between p-nitrophenyl acetate and hexanol with maximal initial velocity(nu(max)) of 4.73 +/- 0.47 microM min(-1) mg(-1), and turnover rate (k(cat)) of 8.67 min(-1).	Hexanols	98-105	CD59 molecule (CD59 blood group)	Homo sapiens	169-175
15593236-2	2005	The catalyst obtained catalysed the transesterification process between p-nitrophenyl acetate and hexanol with maximal initial velocity(nu(max)) of 4.73 +/- 0.47 microM min(-1) mg(-1), and turnover rate (k(cat)) of 8.67 min(-1).	Hexanols	98-105	CD59 molecule (CD59 blood group)	Homo sapiens	220-226
15593236-4	2005	Each imprinted site can be considered as a single molecular reaction vessel, and achieved a k(cat) of 169 min(-1) towards the conversion of p-nitrophenyl acetate in hexanol.	4-nitrophenyl acetate	140-161	CD59 molecule (CD59 blood group)	Homo sapiens	106-112
15593236-4	2005	Each imprinted site can be considered as a single molecular reaction vessel, and achieved a k(cat) of 169 min(-1) towards the conversion of p-nitrophenyl acetate in hexanol.	Hexanols	165-172	CD59 molecule (CD59 blood group)	Homo sapiens	106-112
16035220-4	2005	During cystometry, saline was infused into the patient"s bladder at a constant rate of 30 ml min(-1) until it was full, and the volume of the bladder was recorded every 30 s by the bladder volume monitor.	Sodium Chloride	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
15870622-12	2005	Indomethacin (-2.43 +/- 0.95 mL x min(-1), P < 0.007) and celecoxib (-3.88 +/- 0.94 mL x min(-1), P < 0.0001) significantly reduced free water clearance compared with placebo during recovery.	Celecoxib	61-70	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
15653751-6	2005	Cell death was only observed in the presence of cycloheximide or after a pulse through CD3 or CD59, correlating with a net reduction in cellular Fas-associated death domain-like IL-1beta-converting enzyme-inhibitory protein long (c-FLIPL) and c-FLIPS expression.	Cycloheximide	48-61	CD59 molecule (CD59 blood group)	Homo sapiens	94-98
15884375-7	2005	The oxygen flux was negative (consumption) at a rate of -4.9+/-0.5 nmoles cm(-2) min(-1) O2.	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
15884375-7	2005	The oxygen flux was negative (consumption) at a rate of -4.9+/-0.5 nmoles cm(-2) min(-1) O2.	Oxygen	89-91	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
15723960-6	2005	In normotensive controls, midwall shortening increased from baseline during 2 microg x kg(-1) x min(-1) dobutamine by an average of 16+/-4.5% (P<0.01); a value of 2 standard deviations below this mean response was taken as the lower limit of normal.	Dobutamine	104-114	CD59 molecule (CD59 blood group)	Homo sapiens	96-102
15821661-4	2005	Myocardial fractional flow reserve was measured for the intermediate lesions under the condition of maximum hyperemia induced by intravenous adenosine (140 microg x kg(-1) x min(-1).	Adenosine	141-150	CD59 molecule (CD59 blood group)	Homo sapiens	174-180
15852628-4	2005	After stabilization of anesthesia, landiolol hydrochloride was administered at a rate of 0.04 mg x kg(-1) x min(-1) for 30 min after 0.125 mg x kg(-1) x min(-1).	landiolol	35-58	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
15852628-4	2005	After stabilization of anesthesia, landiolol hydrochloride was administered at a rate of 0.04 mg x kg(-1) x min(-1) for 30 min after 0.125 mg x kg(-1) x min(-1).	landiolol	35-58	CD59 molecule (CD59 blood group)	Homo sapiens	153-159
15809555-4	2005	In relation to exercise training status, basal glucose uptake was significantly (P<0.05) elevated by approximately 75% in the endurance-trained versus sedentary men (20.1+/-2.1 vs 11.9+/-1.9 pmol.mg protein-1.min-1, respectively).	Glucose	47-54	CD59 molecule (CD59 blood group)	Homo sapiens	212-217
15752405-6	2005	The reference point for the control group was the time point at which doses of norepinephrine exceeded 0.3 microg kg(-1) min(-1).	Norepinephrine	79-93	CD59 molecule (CD59 blood group)	Homo sapiens	121-127
15947836-7	2005	RESULTS: Patients presenting creatinine clearance < 30 ml/min/1.73 m(2) had higher iPTH values, but normal serum levels for calcium, phosphorus, alkaline phosphatase and tCO2.	Creatinine	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
15752380-8	2005	Caffeine clearance was 0.083 l min(-1) (CV 38%) and decreased to 0.038 l min(-1) in presence of oral contraceptive therapy, its volume of distribution was 38.6 l (CV 20%) and its absorption rate constant was 0.064 l min(-1) (CV 50%).	Caffeine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	31-37
15752380-8	2005	Caffeine clearance was 0.083 l min(-1) (CV 38%) and decreased to 0.038 l min(-1) in presence of oral contraceptive therapy, its volume of distribution was 38.6 l (CV 20%) and its absorption rate constant was 0.064 l min(-1) (CV 50%).	Caffeine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	73-79
15752380-8	2005	Caffeine clearance was 0.083 l min(-1) (CV 38%) and decreased to 0.038 l min(-1) in presence of oral contraceptive therapy, its volume of distribution was 38.6 l (CV 20%) and its absorption rate constant was 0.064 l min(-1) (CV 50%).	Caffeine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	73-79
15752380-10	2005	Ephedrine was eliminated mostly renally, with a clearance of 0.34 l min(-1) (CV 11%), and a volume of distribution of 181 l (CV 19%).	Ephedrine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
15731532-4	2005	min(-1) (median, interquartile 0.05-0.1) of carperitide for 65 h (median, interquartile 22-142); 51% were assessed as class III or IV according to the Killip classification; 82% of the patients were assessed as clinically improved after carperitide treatment.	NPPA protein, human	44-55	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
15725316-6	2005	Following the failure of other agents (chloral hydrate and/or midazolam), dexmedetomidine was administered as a loading dose of 0.3-1.0 microg x kg(-1) x min(-1) over 5-10 min followed by an infusion of 0.5-1.0 microg x kg(-1) x h(-1).	Dexmedetomidine	74-89	CD59 molecule (CD59 blood group)	Homo sapiens	154-160
15766396-1	2005	AIM: To construct an eukaryotic expression system of human mutant CD59 (hmCD59) gene, and investigate the effect of hmCD59 on diabetic vascular complications.	hmcd59	72-78	CD59 molecule (CD59 blood group)	Homo sapiens	66-70
15708682-5	2005	Results showed that 11.7% 1-butanol, 76.9 mM sodium dodecyl sulphate (SDS), pH of 6.73 and a flow rate of 1.35 ml min(-1) are the best conditions for separation of these compounds.	1-Butanol	26-35	CD59 molecule (CD59 blood group)	Homo sapiens	114-120
15461587-3	2005	COS-7 cells transiently transfected with human PGHS-2 also showed HPETE- or H2O2-dependent NO decay (0.44+/-0.016 and 0.20+/-0.04 nmol x min(-1) x 10(6) cells(-1) for 2.4 microM HPETE and 500 microM H2O2 respectively).	15-hydroperoxy-5,8,11,13-eicosatetraenoic acid	66-71	CD59 molecule (CD59 blood group)	Homo sapiens	137-143
15461587-3	2005	COS-7 cells transiently transfected with human PGHS-2 also showed HPETE- or H2O2-dependent NO decay (0.44+/-0.016 and 0.20+/-0.04 nmol x min(-1) x 10(6) cells(-1) for 2.4 microM HPETE and 500 microM H2O2 respectively).	Hydrogen Peroxide	76-80	CD59 molecule (CD59 blood group)	Homo sapiens	137-143
15461587-4	2005	Finally, purified PGHS-2 consumed NO in the presence of HPETE or H2O2 (168 and 140 microM x min(-1) x microM enzyme(-1) for HPETE and H2O2 respectively), in a haem-dependent manner, with 20 nM enzyme consuming up to 4 microM NO.	Hydrogen Peroxide	65-69	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
15461587-4	2005	Finally, purified PGHS-2 consumed NO in the presence of HPETE or H2O2 (168 and 140 microM x min(-1) x microM enzyme(-1) for HPETE and H2O2 respectively), in a haem-dependent manner, with 20 nM enzyme consuming up to 4 microM NO.	15-hydroperoxy-5,8,11,13-eicosatetraenoic acid	56-61	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
15461587-4	2005	Finally, purified PGHS-2 consumed NO in the presence of HPETE or H2O2 (168 and 140 microM x min(-1) x microM enzyme(-1) for HPETE and H2O2 respectively), in a haem-dependent manner, with 20 nM enzyme consuming up to 4 microM NO.	Hydrogen Peroxide	134-138	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
15693824-4	2005	Nitrate reduction varied between individuals (mean 85.4 +/- 15.9 nmol nitrite min(-1) with 10 ml 1 mm KNO(3) mouth wash) and was found to be concentrated at the rear of the tongue dorsal surface.	Nitrates	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
15693824-4	2005	Nitrate reduction varied between individuals (mean 85.4 +/- 15.9 nmol nitrite min(-1) with 10 ml 1 mm KNO(3) mouth wash) and was found to be concentrated at the rear of the tongue dorsal surface.	Nitrites	70-77	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
15667573-5	2005	Recent in vitro evidence indicates that one of the key membrane complement regulators, CD59, is inactivated by glycation in the presence of high concentrations of glucose or other glycating sugars.	Glucose	163-170	CD59 molecule (CD59 blood group)	Homo sapiens	87-91
15667573-5	2005	Recent in vitro evidence indicates that one of the key membrane complement regulators, CD59, is inactivated by glycation in the presence of high concentrations of glucose or other glycating sugars.	Sugars	190-196	CD59 molecule (CD59 blood group)	Homo sapiens	87-91
15675927-9	2005	RESULTS: The median tolerated dose of remifentanil was 0.127 microg.kg(-1).min(-1) (range: 0.053-0.3 microg.kg(-1).min(-1)).	Remifentanil	38-50	CD59 molecule (CD59 blood group)	Homo sapiens	75-81
15389819-2	2005	They express the glycosylphosphatidylinositol (GPI)-anchored complement regulatory protein CD59, which has been shown to be transferred to spermatozoa and erythrocytes.	Glycosylphosphatidylinositols	17-45	CD59 molecule (CD59 blood group)	Homo sapiens	91-95
15389819-2	2005	They express the glycosylphosphatidylinositol (GPI)-anchored complement regulatory protein CD59, which has been shown to be transferred to spermatozoa and erythrocytes.	Glycosylphosphatidylinositols	47-50	CD59 molecule (CD59 blood group)	Homo sapiens	91-95
15675927-9	2005	RESULTS: The median tolerated dose of remifentanil was 0.127 microg.kg(-1).min(-1) (range: 0.053-0.3 microg.kg(-1).min(-1)).	Remifentanil	38-50	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
16086552-4	2005	The experimentally determined Km and V(max) were 7.14 +/- 0.32 mM and 0.85 +/- 0.32 nmole Tyr formed min(-1) x mg protein(-1) using Phe as substrate.	Tyrosine	90-93	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
15606435-5	2005	RESULTS: Of the 18 subjects, one subject was found to be a very poor metabolizer of lornoxicam with a long t(1/2) of 106 h, a low CL/F of 0.71 ml min(-1), and a high AUC(0-infinity) of 187.6 microg ml(-1) h. Genotyping studies revealed that this subject was heterozygous for CYP2C9*3 and a new variant CYP2C9 allele.	lornoxicam	84-94	CD59 molecule (CD59 blood group)	Homo sapiens	146-152
15494471-10	2005	clearances of morphine, M3G, and M6G from the fetus were 69 +/- 17, 2.3 +/- 0.60, and 1.6 +/- 0.24 ml x min(-1), respectively.	Morphine	14-22	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
16086552-4	2005	The experimentally determined Km and V(max) were 7.14 +/- 0.32 mM and 0.85 +/- 0.32 nmole Tyr formed min(-1) x mg protein(-1) using Phe as substrate.	Phenylalanine	132-135	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
16086552-5	2005	For SCMC the values were 25.24 +/- 5.91 mM and 0.79 +/- 0.09 nmole SCMC (RIS) S-oxides formed min(-1) x mg protein(-1).	Carbocysteine	4-8	CD59 molecule (CD59 blood group)	Homo sapiens	94-100
16086552-5	2005	For SCMC the values were 25.24 +/- 5.91 mM and 0.79 +/- 0.09 nmole SCMC (RIS) S-oxides formed min(-1) x mg protein(-1).	Oxides	80-86	CD59 molecule (CD59 blood group)	Homo sapiens	94-100
16086552-6	2005	The experimentally determined Km and V(max) for the cofactor BH4 were 6.81 +/- 0.21 microM and 0.41 +/- 0.004 nmole Tyr formed min(-1) x mg protein(-1) for Phe and 7.24 +/- 0.19 microM and 0.42 +/- 0.002 nmole SCMC (R/S) S-oxides formed min(-1) x mg protein(-1) for SCMC.	sapropterin	61-64	CD59 molecule (CD59 blood group)	Homo sapiens	127-133
16086552-6	2005	The experimentally determined Km and V(max) for the cofactor BH4 were 6.81 +/- 0.21 microM and 0.41 +/- 0.004 nmole Tyr formed min(-1) x mg protein(-1) for Phe and 7.24 +/- 0.19 microM and 0.42 +/- 0.002 nmole SCMC (R/S) S-oxides formed min(-1) x mg protein(-1) for SCMC.	sapropterin	61-64	CD59 molecule (CD59 blood group)	Homo sapiens	237-243
16086552-6	2005	The experimentally determined Km and V(max) for the cofactor BH4 were 6.81 +/- 0.21 microM and 0.41 +/- 0.004 nmole Tyr formed min(-1) x mg protein(-1) for Phe and 7.24 +/- 0.19 microM and 0.42 +/- 0.002 nmole SCMC (R/S) S-oxides formed min(-1) x mg protein(-1) for SCMC.	Tyrosine	116-119	CD59 molecule (CD59 blood group)	Homo sapiens	127-133
16086552-6	2005	The experimentally determined Km and V(max) for the cofactor BH4 were 6.81 +/- 0.21 microM and 0.41 +/- 0.004 nmole Tyr formed min(-1) x mg protein(-1) for Phe and 7.24 +/- 0.19 microM and 0.42 +/- 0.002 nmole SCMC (R/S) S-oxides formed min(-1) x mg protein(-1) for SCMC.	Tyrosine	116-119	CD59 molecule (CD59 blood group)	Homo sapiens	237-243
16086552-6	2005	The experimentally determined Km and V(max) for the cofactor BH4 were 6.81 +/- 0.21 microM and 0.41 +/- 0.004 nmole Tyr formed min(-1) x mg protein(-1) for Phe and 7.24 +/- 0.19 microM and 0.42 +/- 0.002 nmole SCMC (R/S) S-oxides formed min(-1) x mg protein(-1) for SCMC.	Phenylalanine	156-159	CD59 molecule (CD59 blood group)	Homo sapiens	127-133
16086552-6	2005	The experimentally determined Km and V(max) for the cofactor BH4 were 6.81 +/- 0.21 microM and 0.41 +/- 0.004 nmole Tyr formed min(-1) x mg protein(-1) for Phe and 7.24 +/- 0.19 microM and 0.42 +/- 0.002 nmole SCMC (R/S) S-oxides formed min(-1) x mg protein(-1) for SCMC.	Phenylalanine	156-159	CD59 molecule (CD59 blood group)	Homo sapiens	237-243
16086552-6	2005	The experimentally determined Km and V(max) for the cofactor BH4 were 6.81 +/- 0.21 microM and 0.41 +/- 0.004 nmole Tyr formed min(-1) x mg protein(-1) for Phe and 7.24 +/- 0.19 microM and 0.42 +/- 0.002 nmole SCMC (R/S) S-oxides formed min(-1) x mg protein(-1) for SCMC.	Carbocysteine	210-214	CD59 molecule (CD59 blood group)	Homo sapiens	127-133
16086552-6	2005	The experimentally determined Km and V(max) for the cofactor BH4 were 6.81 +/- 0.21 microM and 0.41 +/- 0.004 nmole Tyr formed min(-1) x mg protein(-1) for Phe and 7.24 +/- 0.19 microM and 0.42 +/- 0.002 nmole SCMC (R/S) S-oxides formed min(-1) x mg protein(-1) for SCMC.	Oxides	223-229	CD59 molecule (CD59 blood group)	Homo sapiens	127-133
15290118-3	2005	METHODS: Myocardial blood flow (MBF; ml min(-1) g(-1)) was measured at rest, during adenosine-induced (140 microg kg(-1) min(-1) over 7 min) hyperaemia (mainly non-endothelium dependent) and immediately after supine bicycle exercise (endothelium-dependent) stress in ten healthy volunteers and in nine hypercholesterolaemic subjects using 15O-labelled water and positron emission tomography.	Adenosine	84-93	CD59 molecule (CD59 blood group)	Homo sapiens	121-127
16086552-6	2005	The experimentally determined Km and V(max) for the cofactor BH4 were 6.81 +/- 0.21 microM and 0.41 +/- 0.004 nmole Tyr formed min(-1) x mg protein(-1) for Phe and 7.24 +/- 0.19 microM and 0.42 +/- 0.002 nmole SCMC (R/S) S-oxides formed min(-1) x mg protein(-1) for SCMC.	Carbocysteine	266-270	CD59 molecule (CD59 blood group)	Homo sapiens	127-133
15674525-5	2005	The infusion rate of propofol for achieving the sedation score of level 3 (drowsy, responds to verbal stimulation) was 1.74 +/- 0.82 mg kg(-1) h(-1) (mean +/- SD, n = 7) when the plasma propofol concentration and the total body clearance were 0.85 +/- 0.24 microg ml(-1) and 1.83 +/- 0.54 l min(-1) (mean +/- SD, n =7), respectively.	Propofol	21-29	CD59 molecule (CD59 blood group)	Homo sapiens	291-297
15562384-6	2005	The area under the curve (30-150) for EGP was significantly greater in the gliclazide group than in the nondiabetic control group (109 +/- 11 vs 198 +/- 22 mg/kg per min 2 ; P > .02) but not significantly different in the repaglinide group (153 +/- 25 mg/kg per min 2 ; P = .17).	Gliclazide	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
15567387-6	2005	AFM measurements revealed the films to be conformal with a surface roughness equivalent to that of the underlying polystyrene substrate with film growth rates of approximately 0.5 nm min(-1).	Polystyrenes	114-125	CD59 molecule (CD59 blood group)	Homo sapiens	183-189
15562384-6	2005	The area under the curve (30-150) for EGP was significantly greater in the gliclazide group than in the nondiabetic control group (109 +/- 11 vs 198 +/- 22 mg/kg per min 2 ; P > .02) but not significantly different in the repaglinide group (153 +/- 25 mg/kg per min 2 ; P = .17).	Gliclazide	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	265-270
16060122-5	2005	Oxygen induced significant increments in glomerular filtration rate (90 +/- 21 to 111 +/- 36 mL/min/1.73 m2, p = 0.03), sodium filtered load (10 +/- 3 to 12 +/- 5 mEq/min, p = 0.004), sodium excreted load (79 +/- 67 to 194 +/- 106 mEq/day, p = 0.0006), fractional excretion of sodium (0.51 +/- 0.49 to 1.30 +/- 1.32%, p = 0.015) diuresis (1048 +/- 548 to 1893 +/- 440 mL/day, p = 0.002), osmolar clearance (1.43 +/- 0.7 to 2.08 +/- 0.6 mOsm/min, p = 0.008) and decreased hematocrit (48 +/- 4 to 44 +/- 3%, p = 0.0038).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
16060094-1	2005	Authors present an 11-year old girl with non-specific clinical symptoms with increase of inflammatory indices and acute non-oliguric renal failure: creatinine clearance - 55 ml/min/1.73 m2.	Creatinine	148-158	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
15714797-3	2005	The determination of forsythoside A was carried out with YWG-C18 column(4.6 mm x 250 mm,10 microm), using acetonitrile-water-Acetic acid (17:83:0.4) as mobile phase at a flow rate of 1.0 mL x min(-1) and detected at the wavelength 280 nm.	forsythiaside	21-35	CD59 molecule (CD59 blood group)	Homo sapiens	192-198
15654448-6	2004	RESULTS: The fractional catabolic rate (min-1) of the lipid emulsion before and after treatment with captopril (0.012 +/- 0.003 and 0.011 +/- 0.003, respectively; p = 0.85, n.s.)	Captopril	101-110	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
15579544-3	2004	However, as a result of the reduction in pyruvate availability, calculated flux through the PDC reaction was at least 2-fold lower in the glycogen depleted state compared with normal (21.81 +/- 2.62 and 9.41 +/- 0.63 nmol acetyl-CoA min(-1) (mg protein)(-1), respectively; P < 0.001).	Pyruvic Acid	41-49	CD59 molecule (CD59 blood group)	Homo sapiens	233-239
15579544-3	2004	However, as a result of the reduction in pyruvate availability, calculated flux through the PDC reaction was at least 2-fold lower in the glycogen depleted state compared with normal (21.81 +/- 2.62 and 9.41 +/- 0.63 nmol acetyl-CoA min(-1) (mg protein)(-1), respectively; P < 0.001).	Glycogen	138-146	CD59 molecule (CD59 blood group)	Homo sapiens	233-239
15638162-5	2004	Water samples need a pH adjustment to values lower than 3 units and must be percolated through the cartridges with flow rates over 5 mL min(-1).	Water	0-5	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
15682803-10	2004	By administration of 10 mg of ephedrine, blood pressure increased to 130/80 mmHg with heart rate of 55 beats x min(-1).	Ephedrine	30-39	CD59 molecule (CD59 blood group)	Homo sapiens	111-117
15543155-0	2004	Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin.	Cholesterol	33-44	CD59 molecule (CD59 blood group)	Homo sapiens	6-10
15543155-3	2004	We show here that ILY, via its domain 4 structure, binds to the glycosyl-phosphatidylinositol-linked membrane protein human CD59 (huCD59).	Glycosylphosphatidylinositols	64-93	CD59 molecule (CD59 blood group)	Homo sapiens	124-128
16114550-5	2004	Both CD55 and CD59 were found in membrane proteins in control group, and medium supernatants of glucose, insulin, glucose + insulin group at 48 h after the inducement.	Glucose	96-103	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
16114550-5	2004	Both CD55 and CD59 were found in membrane proteins in control group, and medium supernatants of glucose, insulin, glucose + insulin group at 48 h after the inducement.	Glucose	114-121	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
15628645-11	2004	Within 30 minutes after amiodarone administration, ventricular heart rate decreased significantly from 152 +/- 12 to 88 +/- 17 (p < 0.0001) beats min(-1) in patients who converted to sinus rhythm and from 157 +/- 14 to 98 +/- 16 beats min(-1) in patients who did not.	Amiodarone	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	149-155
15628645-11	2004	Within 30 minutes after amiodarone administration, ventricular heart rate decreased significantly from 152 +/- 12 to 88 +/- 17 (p < 0.0001) beats min(-1) in patients who converted to sinus rhythm and from 157 +/- 14 to 98 +/- 16 beats min(-1) in patients who did not.	Amiodarone	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	238-244
15492942-5	2004	Three years after transplantation, his creatinine level is 1.7 mg/dL (130 micromol/L), and corrected iothalamate clearance is 53 mL/min/1.73 m2 .	Iothalamic Acid	101-112	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
15273243-8	2004	The results showed that the ventilatory response to carbon dioxide above the set point was increased in men compared with women before exposure to episodic hypoxia, independent of the oxygen level that was maintained during the rebreathing trials (50 Torr: men, 5.19 +/- 0.82 vs. women, 4.70 +/- 0.77 l x min(-1) x Torr(-1); 150 Torr: men, 4.33 +/- 1.15 vs. women, 3.21 +/- 0.58 l x min(-1) x Torr(-1)).	Carbon Dioxide	52-66	CD59 molecule (CD59 blood group)	Homo sapiens	305-311
15273243-8	2004	The results showed that the ventilatory response to carbon dioxide above the set point was increased in men compared with women before exposure to episodic hypoxia, independent of the oxygen level that was maintained during the rebreathing trials (50 Torr: men, 5.19 +/- 0.82 vs. women, 4.70 +/- 0.77 l x min(-1) x Torr(-1); 150 Torr: men, 4.33 +/- 1.15 vs. women, 3.21 +/- 0.58 l x min(-1) x Torr(-1)).	Carbon Dioxide	52-66	CD59 molecule (CD59 blood group)	Homo sapiens	383-389
15273243-9	2004	Moreover, relative to baseline measures, the ventilatory response to carbon dioxide in the presence of low and high oxygen levels increased to a greater extent in men compared with women after exposure to episodic hypoxia (50 Torr: men, 9.52 +/- 1.40 vs. women, 5.97 +/- 0.71 l x min(-1) x Torr(-1); 150 Torr: men, 5.73 +/- 0.81 vs. women, 3.83 +/- 0.56 l x min(-1) x Torr(-1)).	Carbon Dioxide	69-83	CD59 molecule (CD59 blood group)	Homo sapiens	280-286
15273243-9	2004	Moreover, relative to baseline measures, the ventilatory response to carbon dioxide in the presence of low and high oxygen levels increased to a greater extent in men compared with women after exposure to episodic hypoxia (50 Torr: men, 9.52 +/- 1.40 vs. women, 5.97 +/- 0.71 l x min(-1) x Torr(-1); 150 Torr: men, 5.73 +/- 0.81 vs. women, 3.83 +/- 0.56 l x min(-1) x Torr(-1)).	Carbon Dioxide	69-83	CD59 molecule (CD59 blood group)	Homo sapiens	358-364
15514500-5	2004	RESULTS: Maximal oxygen uptake increased by 18% to 50.4 +/- 3.1 mL x kg(-1) x min(-1) (P < 0.001).	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
15514504-8	2004	In addition, bicarbonate ingestion diminished the amplitude of the slow component 29% (463 +/- 43 vs 649 +/- 53 mL x min(-1); P = 0.040).	Bicarbonates	13-24	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
15475021-4	2004	Furthermore, homocysteine increased in the high-intensity-low-frequency (0.98 +/- 2.32 micromol/L) and high-intensity-high-frequency (0.93 +/- 2.56 micromol/L) groups, while aerobic fitness increased in the moderate-intensity-high-frequency (0.99 +/- 2.01 mL min(-1) kg(-1)) and high-intensity-high-frequency (1.77 +/- 2.97 mL min(-1) kg(-1)) groups (all P < 0.003).	Homocysteine	13-25	CD59 molecule (CD59 blood group)	Homo sapiens	259-265
15475021-4	2004	Furthermore, homocysteine increased in the high-intensity-low-frequency (0.98 +/- 2.32 micromol/L) and high-intensity-high-frequency (0.93 +/- 2.56 micromol/L) groups, while aerobic fitness increased in the moderate-intensity-high-frequency (0.99 +/- 2.01 mL min(-1) kg(-1)) and high-intensity-high-frequency (1.77 +/- 2.97 mL min(-1) kg(-1)) groups (all P < 0.003).	Homocysteine	13-25	CD59 molecule (CD59 blood group)	Homo sapiens	327-333
15333644-7	2004	External phosphorus markedly affected influx: roots averaged 5, 16, and 34 pmol P min(-1) in the apical 20 mm when exposed to 1, 5, and 10 microM P solutions, respectively.	Phosphorus	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	82-88
15600265-11	2004	In severe kidney disease (GFR 15-29 mL/min/1.73 m2), the hazards risk for death was 0.21 (0.08, 0.53) for aspirin alone, 0.17 (0.06, 0.51) for aspirin with beta-blockers, and 0.35 (0.09, 1.42) for aspirin with beta-blockers and ace-inhibitors.	Aspirin	106-113	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
15464494-3	2004	METHODS: This was a multicenter, prospective, cohort study in which 108 patients at high risk of postoperative acute renal failure and undergoing cardiac surgery with cardiopulmonary bypass were treated with fenoldopam mesylate (0.08 microg x kg(-1) x min(-1)) starting at the induction of anesthesia and throughout at least the next 24 hours.	Fenoldopam	208-227	CD59 molecule (CD59 blood group)	Homo sapiens	252-258
15388552-9	2004	RCP occurred on average at a significantly (p = 0.043) higher oxygen uptake (+0.15 l x min(-1)) compared with the first test.	Oxygen	62-68	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
15470169-5	2004	Heart rate fell to 38, 40 and 42 beats x min(-1) respectively two minutes after the sufentanil injection in these three patients, and progressed to asystole in the third.	Sufentanil	84-94	CD59 molecule (CD59 blood group)	Homo sapiens	41-47
15578466-9	2004	MEASUREMENTS AND MAIN RESULTS: Bland-Altman analysis of CO measurements before CPB yielded a bias, precision, and percent error of 0.04 L/min +/- 1.07 L/min (44.8%) for NICO, 0.18 L/min +/- 1.01 L/min (41.7%) for TDCO, and 0.29 L/min +/- 1.40 L/min (57.5%) for CCO compared with simultaneous UFP CO measurements, respectively.	Niacin	169-173	CD59 molecule (CD59 blood group)	Homo sapiens	138-147
15552949-4	2004	Mean PaO2 and PaCO2 were 76.5 mmHg and 45.5 mmHg, respectively, under nasal oxygen of 1.67 l x min(-1).	Oxygen	76-82	CD59 molecule (CD59 blood group)	Homo sapiens	95-101
15325283-3	2004	Confocal microscopic colocalization experiments with GM(1) gangliosides and the GPI-anchored CD59 molecules showed enrichment of HLA I, HLA-DR, and ICAM-1 molecules in specific membrane domains (lipid rafts) excluding the transferrin receptor.	Glycosylphosphatidylinositols	80-83	CD59 molecule (CD59 blood group)	Homo sapiens	93-97
15385015-4	2004	METHODS: Twenty patients were randomized to receive a titrated infusion of remifentanil (0-1 microg x kg(-1) x min(-1)) or a standard dose of fentanyl (30 microg x kg(-1)) prebypass plus morphine (1 mg x kg(-1)) on rewarming.	Remifentanil	75-87	CD59 molecule (CD59 blood group)	Homo sapiens	111-118
15474879-6	2004	RESULTS: Maximal oxygen consumption (corrected for body weight) values were 29.9 +/- 6.7 mL x kg(-1) x min(-1) in group 1 and 47.2 +/- 5.3 mL x kg(-1) x min(-1) in group 2 (P < 0.05).	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	103-109
15329581-5	2004	Furthermore, the authors tested the hypothesis that the addition of fenoldopam (0.1 microg x kg(-1) x min(-1)) to a combination of norepinephrine and dobutamine (5 microg x kg(-1) x min(-1)) may improve gastric mucosal perfusion in septic shock.	Fenoldopam	68-78	CD59 molecule (CD59 blood group)	Homo sapiens	102-109
15351058-2	2004	The best carrier solvent was found to be 0.01 M NaOH and it was determined at optimum conditions such as flow rate of 1 ml min(-1) and wavelength of 292 nm.	Sodium Hydroxide	48-52	CD59 molecule (CD59 blood group)	Homo sapiens	123-129
15329581-5	2004	Furthermore, the authors tested the hypothesis that the addition of fenoldopam (0.1 microg x kg(-1) x min(-1)) to a combination of norepinephrine and dobutamine (5 microg x kg(-1) x min(-1)) may improve gastric mucosal perfusion in septic shock.	Fenoldopam	68-78	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
15329588-9	2004	Remifentanil mean infusion rate was 0.13 +/- 0.03 microg x kg(-1) x min(-1), whereas morphine mean infusion rate was 0.68 +/- 0.28 microg x kg(-1) x min(-1).	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
15333478-8	2004	min(-1) were found before and after lunch using blood glucose data and -0.31 +/- 1.23 and 0.43 +/- 1.26 using Biographer data.	Blood Glucose	48-61	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
15595588-6	2004	Patients who received alfentanil had significantly lower heart rates than those who received nerve blockade only (96.0+/-15.6 vs. 115.9+/-23.2 beats min(-1), P < 0.001).	Alfentanil	22-32	CD59 molecule (CD59 blood group)	Homo sapiens	149-155
15327310-1	2004	In this communication, we report the synthesis of the three generations of Frechet-type poly(aryl ether) dendrimers with a diselenide core that demonstrate generation-dependent glutathione peroxidase (GPx) activity with initial reduction rates as high as 2431.20 muM min-1 for the third-generation product, around 1400 times faster than Ebselen.	diselenium	123-133	CD59 molecule (CD59 blood group)	Homo sapiens	267-272
15354037-1	2004	UNLABELLED: Studies that have investigated oxidation of a single carbohydrate (CHO) during exercise have reported oxidation rates of up to 1 g x min(-1).	Carbohydrates	65-77	CD59 molecule (CD59 blood group)	Homo sapiens	145-151
15354037-1	2004	UNLABELLED: Studies that have investigated oxidation of a single carbohydrate (CHO) during exercise have reported oxidation rates of up to 1 g x min(-1).	CAV protocol	79-82	CD59 molecule (CD59 blood group)	Homo sapiens	145-151
15354037-2	2004	Recent studies from our laboratory have shown that a mixture of glucose and sucrose or glucose and fructose ingested at a high rate (1.8 g x min(-1)) leads to peak oxidation rates of approximately 1.3 g x min(-1) and results in approximately 20 to 55% higher exogenous CHO oxidation rates compared with the ingestion of an isocaloric amount of glucose.	Glucose	64-71	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
15354037-2	2004	Recent studies from our laboratory have shown that a mixture of glucose and sucrose or glucose and fructose ingested at a high rate (1.8 g x min(-1)) leads to peak oxidation rates of approximately 1.3 g x min(-1) and results in approximately 20 to 55% higher exogenous CHO oxidation rates compared with the ingestion of an isocaloric amount of glucose.	Glucose	64-71	CD59 molecule (CD59 blood group)	Homo sapiens	205-211
15354037-2	2004	Recent studies from our laboratory have shown that a mixture of glucose and sucrose or glucose and fructose ingested at a high rate (1.8 g x min(-1)) leads to peak oxidation rates of approximately 1.3 g x min(-1) and results in approximately 20 to 55% higher exogenous CHO oxidation rates compared with the ingestion of an isocaloric amount of glucose.	Sucrose	76-83	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
15354037-2	2004	Recent studies from our laboratory have shown that a mixture of glucose and sucrose or glucose and fructose ingested at a high rate (1.8 g x min(-1)) leads to peak oxidation rates of approximately 1.3 g x min(-1) and results in approximately 20 to 55% higher exogenous CHO oxidation rates compared with the ingestion of an isocaloric amount of glucose.	Sucrose	76-83	CD59 molecule (CD59 blood group)	Homo sapiens	205-211
15354037-2	2004	Recent studies from our laboratory have shown that a mixture of glucose and sucrose or glucose and fructose ingested at a high rate (1.8 g x min(-1)) leads to peak oxidation rates of approximately 1.3 g x min(-1) and results in approximately 20 to 55% higher exogenous CHO oxidation rates compared with the ingestion of an isocaloric amount of glucose.	Glucose	87-94	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
15354037-2	2004	Recent studies from our laboratory have shown that a mixture of glucose and sucrose or glucose and fructose ingested at a high rate (1.8 g x min(-1)) leads to peak oxidation rates of approximately 1.3 g x min(-1) and results in approximately 20 to 55% higher exogenous CHO oxidation rates compared with the ingestion of an isocaloric amount of glucose.	Glucose	87-94	CD59 molecule (CD59 blood group)	Homo sapiens	205-211
15354037-2	2004	Recent studies from our laboratory have shown that a mixture of glucose and sucrose or glucose and fructose ingested at a high rate (1.8 g x min(-1)) leads to peak oxidation rates of approximately 1.3 g x min(-1) and results in approximately 20 to 55% higher exogenous CHO oxidation rates compared with the ingestion of an isocaloric amount of glucose.	Fructose	99-107	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
15354037-2	2004	Recent studies from our laboratory have shown that a mixture of glucose and sucrose or glucose and fructose ingested at a high rate (1.8 g x min(-1)) leads to peak oxidation rates of approximately 1.3 g x min(-1) and results in approximately 20 to 55% higher exogenous CHO oxidation rates compared with the ingestion of an isocaloric amount of glucose.	Fructose	99-107	CD59 molecule (CD59 blood group)	Homo sapiens	205-211
15354037-2	2004	Recent studies from our laboratory have shown that a mixture of glucose and sucrose or glucose and fructose ingested at a high rate (1.8 g x min(-1)) leads to peak oxidation rates of approximately 1.3 g x min(-1) and results in approximately 20 to 55% higher exogenous CHO oxidation rates compared with the ingestion of an isocaloric amount of glucose.	CAV protocol	269-272	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
15354037-2	2004	Recent studies from our laboratory have shown that a mixture of glucose and sucrose or glucose and fructose ingested at a high rate (1.8 g x min(-1)) leads to peak oxidation rates of approximately 1.3 g x min(-1) and results in approximately 20 to 55% higher exogenous CHO oxidation rates compared with the ingestion of an isocaloric amount of glucose.	Glucose	87-94	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
15354037-2	2004	Recent studies from our laboratory have shown that a mixture of glucose and sucrose or glucose and fructose ingested at a high rate (1.8 g x min(-1)) leads to peak oxidation rates of approximately 1.3 g x min(-1) and results in approximately 20 to 55% higher exogenous CHO oxidation rates compared with the ingestion of an isocaloric amount of glucose.	Glucose	87-94	CD59 molecule (CD59 blood group)	Homo sapiens	205-211
15354037-3	2004	PURPOSE: The purpose of the present study was to examine whether a mixture of glucose, sucrose and fructose ingested at a high rate would result in even higher exogenous CHO oxidation rates (>1.3 g x min(-1)).	Glucose	78-85	CD59 molecule (CD59 blood group)	Homo sapiens	203-209
15354037-3	2004	PURPOSE: The purpose of the present study was to examine whether a mixture of glucose, sucrose and fructose ingested at a high rate would result in even higher exogenous CHO oxidation rates (>1.3 g x min(-1)).	Sucrose	87-94	CD59 molecule (CD59 blood group)	Homo sapiens	203-209
15354037-3	2004	PURPOSE: The purpose of the present study was to examine whether a mixture of glucose, sucrose and fructose ingested at a high rate would result in even higher exogenous CHO oxidation rates (>1.3 g x min(-1)).	Fructose	99-107	CD59 molecule (CD59 blood group)	Homo sapiens	203-209
15354037-5	2004	RESULTS: High peak exogenous CHO oxidation rates were found in the MIX trial (1.70 +/- 0.07 g x min(-1)), which were approximately 44% higher (P < 0.01) compared with the GLU trial (1.18 +/- 0.04 g x min(-1)).	CAV protocol	29-32	CD59 molecule (CD59 blood group)	Homo sapiens	96-102
15354037-5	2004	RESULTS: High peak exogenous CHO oxidation rates were found in the MIX trial (1.70 +/- 0.07 g x min(-1)), which were approximately 44% higher (P < 0.01) compared with the GLU trial (1.18 +/- 0.04 g x min(-1)).	CAV protocol	29-32	CD59 molecule (CD59 blood group)	Homo sapiens	203-209
15354037-6	2004	Endogenous CHO oxidation was lower (P < 0.05) in MIX compared with GLU (0.76 +/- 0.12 and 1.05 +/- 0.06 g x min(-1), respectively).	CAV protocol	11-14	CD59 molecule (CD59 blood group)	Homo sapiens	111-117
15354037-7	2004	CONCLUSION: When glucose, fructose and sucrose are ingested simultaneously at high rates (2.4 g x min(-1)) during cycling exercise, exogenous CHO oxidation rates can reach peak values of approximately 1.7 g x min(-1) and estimated endogenous CHO oxidation is reduced compared with the ingestion of an isocaloric amount of glucose.	Glucose	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	98-104
15354037-7	2004	CONCLUSION: When glucose, fructose and sucrose are ingested simultaneously at high rates (2.4 g x min(-1)) during cycling exercise, exogenous CHO oxidation rates can reach peak values of approximately 1.7 g x min(-1) and estimated endogenous CHO oxidation is reduced compared with the ingestion of an isocaloric amount of glucose.	Glucose	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	209-215
15354037-7	2004	CONCLUSION: When glucose, fructose and sucrose are ingested simultaneously at high rates (2.4 g x min(-1)) during cycling exercise, exogenous CHO oxidation rates can reach peak values of approximately 1.7 g x min(-1) and estimated endogenous CHO oxidation is reduced compared with the ingestion of an isocaloric amount of glucose.	Fructose	26-34	CD59 molecule (CD59 blood group)	Homo sapiens	98-104
15354037-7	2004	CONCLUSION: When glucose, fructose and sucrose are ingested simultaneously at high rates (2.4 g x min(-1)) during cycling exercise, exogenous CHO oxidation rates can reach peak values of approximately 1.7 g x min(-1) and estimated endogenous CHO oxidation is reduced compared with the ingestion of an isocaloric amount of glucose.	Fructose	26-34	CD59 molecule (CD59 blood group)	Homo sapiens	209-215
15354037-7	2004	CONCLUSION: When glucose, fructose and sucrose are ingested simultaneously at high rates (2.4 g x min(-1)) during cycling exercise, exogenous CHO oxidation rates can reach peak values of approximately 1.7 g x min(-1) and estimated endogenous CHO oxidation is reduced compared with the ingestion of an isocaloric amount of glucose.	Sucrose	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	98-104
15354037-7	2004	CONCLUSION: When glucose, fructose and sucrose are ingested simultaneously at high rates (2.4 g x min(-1)) during cycling exercise, exogenous CHO oxidation rates can reach peak values of approximately 1.7 g x min(-1) and estimated endogenous CHO oxidation is reduced compared with the ingestion of an isocaloric amount of glucose.	Sucrose	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	209-215
15354037-7	2004	CONCLUSION: When glucose, fructose and sucrose are ingested simultaneously at high rates (2.4 g x min(-1)) during cycling exercise, exogenous CHO oxidation rates can reach peak values of approximately 1.7 g x min(-1) and estimated endogenous CHO oxidation is reduced compared with the ingestion of an isocaloric amount of glucose.	CAV protocol	142-145	CD59 molecule (CD59 blood group)	Homo sapiens	98-104
15354037-7	2004	CONCLUSION: When glucose, fructose and sucrose are ingested simultaneously at high rates (2.4 g x min(-1)) during cycling exercise, exogenous CHO oxidation rates can reach peak values of approximately 1.7 g x min(-1) and estimated endogenous CHO oxidation is reduced compared with the ingestion of an isocaloric amount of glucose.	CAV protocol	142-145	CD59 molecule (CD59 blood group)	Homo sapiens	209-215
15387172-5	2004	The resolution of cis and trans diastereoisomers on the silica column was obtained by using a mobile phase consisting of n-hexane:tert-butyl methyl ether (96:4) (v/v) at a flow rate of 1 ml min(-1).	Silicon Dioxide	56-62	CD59 molecule (CD59 blood group)	Homo sapiens	190-196
15289374-5	2004	First-pass perfusion imaging was performed during hyperemia (induced by a 4-minute infusion of adenosine at a rate of 140 microg x kg(-1) x min(-1)) and then again in the absence of adenosine with otherwise identical imaging parameters and the same contrast dose.	Adenosine	95-104	CD59 molecule (CD59 blood group)	Homo sapiens	140-146
15138838-4	2004	The rate of exogenous glucose oxidation was approximately 45% lower in women than men (0.5 and 0.6 g min(-1) vs 0.7 and 0.9 g min(-1), between min 40 and 80, and min 80 and 120, respectively).	Glucose	22-29	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
15138838-4	2004	The rate of exogenous glucose oxidation was approximately 45% lower in women than men (0.5 and 0.6 g min(-1) vs 0.7 and 0.9 g min(-1), between min 40 and 80, and min 80 and 120, respectively).	Glucose	22-29	CD59 molecule (CD59 blood group)	Homo sapiens	126-132
15146059-6	2004	Endocytosis of CD59 and MHCI required free membrane cholesterol because it was inhibited by filipin binding to the cell surface.	Cholesterol	52-63	CD59 molecule (CD59 blood group)	Homo sapiens	15-19
15281022-7	2004	The mean rates of appearance for 3-methylhistidine and phenylalanine were 0.44 +/- 0.30 nmol x min(-1) x 100 mL(-1) and 11.2 +/- 5.7 nmol x min(-1) x 100 mL(-1), respectively.	3-methylhistidine	33-50	CD59 molecule (CD59 blood group)	Homo sapiens	95-101
15281022-7	2004	The mean rates of appearance for 3-methylhistidine and phenylalanine were 0.44 +/- 0.30 nmol x min(-1) x 100 mL(-1) and 11.2 +/- 5.7 nmol x min(-1) x 100 mL(-1), respectively.	Phenylalanine	55-68	CD59 molecule (CD59 blood group)	Homo sapiens	95-101
15281022-7	2004	The mean rates of appearance for 3-methylhistidine and phenylalanine were 0.44 +/- 0.30 nmol x min(-1) x 100 mL(-1) and 11.2 +/- 5.7 nmol x min(-1) x 100 mL(-1), respectively.	Phenylalanine	55-68	CD59 molecule (CD59 blood group)	Homo sapiens	140-146
15265142-6	2004	Also, adenosine-stimulated perfusion tended to be higher (3.67+/-0.81 vs. 4.47+/-0.52 mL min(-1) g(-1), P=0.12) and perfusion resistance during adenosine stimulation was significantly lower after running (26+/-6 vs. 18+/-3 mmHg min g mL(-1), P=0.03).	Adenosine	6-15	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
15190961-8	2004	The peak increase in heart rate and cardiac index occurred at a dopamine dose of 4-6 microg x kg(-1) x min(-1).	Dopamine	64-72	CD59 molecule (CD59 blood group)	Homo sapiens	103-109
15285777-6	2004	Compartmental analysis was used to probe the physiological basis of the activation of K: levodopa treatment increased by 15% the apparent distribution volume of [(18)F]fluorodopa in cerebellum (, ml/g) of both patients and control subjects, without significantly altering the unidirectional blood-brain clearance (, ml/g/min) or the relative activity of DOPA decarboxylase (, min(-1)) in putamen.	Levodopa	89-97	CD59 molecule (CD59 blood group)	Homo sapiens	376-383
15264814-4	2004	Time-resolved ultratrace detection of fluorophore (Alexa-Fluor 647)-labeled rabbit anti-mouse antibody down to 500 aM (10-18 M) was accomplished, corresponding to a binding rate of approximately 10 molecules mm-2 min-1.	Alexa Fluor 647	51-66	CD59 molecule (CD59 blood group)	Homo sapiens	213-218
15225598-8	2004	Post-radiation addition of ascorbate and RibCys also affected the quality of CD59(-) mutations induced by carbon-ions.	Ascorbic Acid	27-36	CD59 molecule (CD59 blood group)	Homo sapiens	77-81
15225598-8	2004	Post-radiation addition of ascorbate and RibCys also affected the quality of CD59(-) mutations induced by carbon-ions.	Carbon	106-112	CD59 molecule (CD59 blood group)	Homo sapiens	77-81
15233838-5	2004	Thereafter, a rise in O(2) of 223 +/- 123 ml min(-1) (consistent with the mathematical model, 259 +/- 126 ml min(-1)) was observed between minutes 2 and 10.	Oxygen	22-26	CD59 molecule (CD59 blood group)	Homo sapiens	45-51
15233838-5	2004	Thereafter, a rise in O(2) of 223 +/- 123 ml min(-1) (consistent with the mathematical model, 259 +/- 126 ml min(-1)) was observed between minutes 2 and 10.	Oxygen	22-26	CD59 molecule (CD59 blood group)	Homo sapiens	109-115
15135109-7	2004	Thus, the optimal conditions for the separation of the four glycosphingolipids was obtained with a gradient elution from a 100% chloroform to a 100% acetone:methanol (90:10 (v/v)) mobile phase at 0.2 ml min-1, using a 10% min-1 gradient slope.	Glycosphingolipids	60-78	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
15135109-7	2004	Thus, the optimal conditions for the separation of the four glycosphingolipids was obtained with a gradient elution from a 100% chloroform to a 100% acetone:methanol (90:10 (v/v)) mobile phase at 0.2 ml min-1, using a 10% min-1 gradient slope.	Glycosphingolipids	60-78	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
15071714-4	2004	A flow rate of 40 mL min(-1) (5% of Freon in argon) was used to obtain symmetrical peaks with no tailing.	Chlorofluorocarbons	36-41	CD59 molecule (CD59 blood group)	Homo sapiens	21-27
15144292-3	2004	Simulated oxygen uptake values between 200 and 350 ml x min(-1) were modelled.	Oxygen	10-16	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
15144292-4	2004	The Biro-derived measurement of simulated O(2) uptake significantly underestimated the target value (mean difference -88.5 ml x min(-1), or -31.7%).	Oxygen	42-46	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
15470316-6	2004	RESULTS: Mean maximal oxygen uptake was 73.7+/-7.0 and 47.4+/-7.5 ml x kg(-1) x min(-1) in the 2 groups, respectively.	Oxygen	22-28	CD59 molecule (CD59 blood group)	Homo sapiens	80-86
15159064-2	2004	In this study, we show that antibodies to CD59, as well as to every other GPI-anchored protein tested, inhibited the C1q-triggered release of O(2)(-) from PMN.	o(2)	142-146	CD59 molecule (CD59 blood group)	Homo sapiens	42-46
15114217-6	2004	Each animal received, in a random-order, crossover design, the three test drugs, one at a time: 5 and 10 microg x kg(-1) x min(-1) dopamine, 5 and 10 microg x kg(-1) x min(-1) dobutamine, and 1 and 2 microg x kg(-1) x min(-1) dopexamine.	Dopamine	131-139	CD59 molecule (CD59 blood group)	Homo sapiens	123-129
14990681-6	2004	Resting blood flows in the forearm before infusion of acetylcholine, substance P or sodium nitroprusside were 25 +/- 4, 30 +/- 7 and 29 +/- 5 ml min(-1), respectively, and in the leg were 370 +/- 32, 409 +/- 62 and 330 +/- 30 ml min(-1), respectively.	Nitroprusside	84-104	CD59 molecule (CD59 blood group)	Homo sapiens	145-151
14990681-7	2004	At the highest infusion rate of acetylcholine (16 microg (100 ml tissue)(-1) min(-1)) there was a greater (P < 0.05) increase in Q to the forearm (1864 +/- 476%) than to the leg (569 +/- 86%).	Acetylcholine	32-45	CD59 molecule (CD59 blood group)	Homo sapiens	77-83
14990681-9	2004	The responses to sodium nitroprusside (1 microg (100 ml tissue)(-1) min(-1)) were also greater (P < 0.05) in the forearm (925 +/- 164%) than in the leg (326 +/- 65%).	Nitroprusside	17-37	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
15198243-4	2004	After the start of surgery under general anesthesia, EHR was stable between 80-100 beats x min(-1) but rapid atrial fibrillation developed with a rate of over 140 beats x min(-1) after epidural injection of 0.375% ropivacaine 3 ml.	Ropivacaine	214-225	CD59 molecule (CD59 blood group)	Homo sapiens	171-177
15065880-5	2004	The maximum attainable activity of 0.12 micromol min(-1) (mg of protein)(-1) was observed at an APS concentration ([APS](opt)) of 15 microM.	Adenosine Phosphosulfate	96-99	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
15065880-5	2004	The maximum attainable activity of 0.12 micromol min(-1) (mg of protein)(-1) was observed at an APS concentration ([APS](opt)) of 15 microM.	Adenosine Phosphosulfate	116-119	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
15065880-7	2004	At likely cellular levels of MgATP (2.5 mM) and sulfate (0.4 mM), the overall endogenous rate of PAPS formation under optimum assay conditions was 0.09 micromol min(-1) (mg of protein)(-1).	Adenosine Triphosphate	29-34	CD59 molecule (CD59 blood group)	Homo sapiens	161-167
15065880-7	2004	At likely cellular levels of MgATP (2.5 mM) and sulfate (0.4 mM), the overall endogenous rate of PAPS formation under optimum assay conditions was 0.09 micromol min(-1) (mg of protein)(-1).	Sulfates	48-55	CD59 molecule (CD59 blood group)	Homo sapiens	161-167
15025597-6	2004	was administrated followed by a continuous infusion of remifentanil (0.25 microg x kg(-1) x min(-1) i.v.)	Remifentanil	55-67	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
15216494-6	2004	However, increasing potassium intake should be restricted in patients with glomerular filtration rate (GFR) less than 60 mL/min/1.73 m(2).	Potassium	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
14766716-7	2004	When pressure was applied to cause increasing pain in volunteers (n=11) 0.05 microg kg-1 min-1 remifentanil increased pain tolerance by 50%.	Remifentanil	95-107	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
14977792-4	2004	METHODS: After intrathecal injection, we infused phenylephrine 100 microg min(-1) for 2 min.	Phenylephrine	49-62	CD59 molecule (CD59 blood group)	Homo sapiens	74-80
15181463-4	2004	Before and for 67 min after the fatigue period, muscles contracted at 0.6 contractions x min(-1) in 95% oxygen - 5% carbon dioxide (hyperoxia).	Oxygen	104-110	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
15181463-4	2004	Before and for 67 min after the fatigue period, muscles contracted at 0.6 contractions x min(-1) in 95% oxygen - 5% carbon dioxide (hyperoxia).	Carbon Dioxide	116-130	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
15298350-8	2004	However, dipyridamole-stimulated flow and coronary vascular resistance were blunted in diabetic patients with retinopathy (2.9 +/- 0.9 ml x g(-1) x min(-1) and 34.1 +/- 11.3 mmHg x min x g x ml(-1)) when compared to diabetic patients without retinopathy (4.0 +/- 1.3 ml x g(-1) x min(-1), p=0.04 and 24.6 +/- 7.5 mmHg x min x g x ml(-1), p=0.03) or non-diabetic subjects (4.5 +/- 1.4 ml x g(-1) x min(-1) p=0.008 and 22.2 +/- 8.7 mmHg x min x g x ml(-1), p=0.01).	Dipyridamole	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	148-154
15298350-8	2004	However, dipyridamole-stimulated flow and coronary vascular resistance were blunted in diabetic patients with retinopathy (2.9 +/- 0.9 ml x g(-1) x min(-1) and 34.1 +/- 11.3 mmHg x min x g x ml(-1)) when compared to diabetic patients without retinopathy (4.0 +/- 1.3 ml x g(-1) x min(-1), p=0.04 and 24.6 +/- 7.5 mmHg x min x g x ml(-1), p=0.03) or non-diabetic subjects (4.5 +/- 1.4 ml x g(-1) x min(-1) p=0.008 and 22.2 +/- 8.7 mmHg x min x g x ml(-1), p=0.01).	Dipyridamole	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	280-286
15298350-8	2004	However, dipyridamole-stimulated flow and coronary vascular resistance were blunted in diabetic patients with retinopathy (2.9 +/- 0.9 ml x g(-1) x min(-1) and 34.1 +/- 11.3 mmHg x min x g x ml(-1)) when compared to diabetic patients without retinopathy (4.0 +/- 1.3 ml x g(-1) x min(-1), p=0.04 and 24.6 +/- 7.5 mmHg x min x g x ml(-1), p=0.03) or non-diabetic subjects (4.5 +/- 1.4 ml x g(-1) x min(-1) p=0.008 and 22.2 +/- 8.7 mmHg x min x g x ml(-1), p=0.01).	Dipyridamole	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	280-286
15160958-3	2004	Paroxysmal nocturnal hemoglobinuria (PNH) is a hematopoietic disorder caused by PIGA mutations that lead to a loss of all glycosylphospatidylinositol (GPI)-anchored proteins including, CD55 and CD59.	GPI 1046	151-154	CD59 molecule (CD59 blood group)	Homo sapiens	194-198
15160669-6	2004	In the first operation digoxin and verapamil partly reduced heart rate of rapid atrial fibrillation from 140-170 to 110-140 beats x min-1, which made us use another drug, a short acting selective beta 1 blocker landiolol in the second operation.	Digoxin	23-30	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
15160669-6	2004	In the first operation digoxin and verapamil partly reduced heart rate of rapid atrial fibrillation from 140-170 to 110-140 beats x min-1, which made us use another drug, a short acting selective beta 1 blocker landiolol in the second operation.	Verapamil	35-44	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
15139527-5	2004	The uptake rate of clonidine was saturable with an affinity constant (Kt) of 1.1 mM and a Vmax value of 27 nmol x min(-1) x mg(-1) of protein.	Clonidine	19-28	CD59 molecule (CD59 blood group)	Homo sapiens	114-120
15160669-7	2004	Landiolol successfully reduced the heart rate of rapid atrial fibrillation from 140-160 to 80-90 beats x min-1.	landiolol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
19471732-9	2004	Anesthesia was maintained with 0.4 microg.kg-1.h-1 dexmedetomidine and 0.3 microg.kg-1.min-1 remifentanil in continuous infusion, and 3 microg.mL-1 propofol in target-controlled infusion.	Remifentanil	93-105	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
15108975-4	2004	While maintenance of anesthesia was ensured by a continuous infusion of etomidate, increased concentrations of remifentanil (from 0.1 to 1 microg x kg(-1) x min(-1)) were infused in steps of 5 min under hemodynamic monitoring, including left and right atrial pressures, systemic and pulmonary arterial pressures, and left and right cardiac indices.	Remifentanil	111-123	CD59 molecule (CD59 blood group)	Homo sapiens	157-163
15108975-8	2004	RESULTS: Remifentanil produced a dose-dependent and significant decrease in systemic arterial pressure and vascular resistances (n = 9) from a concentration of 0.25 microg x kg(-1) x min(-1).	Remifentanil	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	183-189
15108978-5	2004	In 12 patients (6 phenytoin, 6 control), vecuronium was infused at 7.5 microg x kg(-1) x min(-1) until the first response (T1) of each train-of-four decreased by 50%; in the remaining 10 patients (5 phenytoin, 5 control), 200 microg/kg vecuronium was infused over 10 min.	Vecuronium Bromide	41-51	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
15104241-8	2004	The biotransformation of LAAM to norLAAM exhibited monophasic kinetics with apparent Km and Vmax values of 105 +/- 57 microM and 86.8 +/- 15.6 pmol mg(-1) protein min(-1), respectively.	Methadyl Acetate	25-29	CD59 molecule (CD59 blood group)	Homo sapiens	163-169
15104241-8	2004	The biotransformation of LAAM to norLAAM exhibited monophasic kinetics with apparent Km and Vmax values of 105 +/- 57 microM and 86.8 +/- 15.6 pmol mg(-1) protein min(-1), respectively.	paracymethadol	33-40	CD59 molecule (CD59 blood group)	Homo sapiens	163-169
15005300-6	2004	Mean bias for oxygen and nitrous oxide uptake was 0.003 l min(-1), for isoflurane 0.0001 l min(-1) and for carbon dioxide 0.001 l min(-1).	Oxygen	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
14998432-4	2004	RESULTS: Incubation of tizanidine (80 nm) with human liver microsomes resulted in time- and NADPH-dependent substrate consumption with a half-life of 50 min, initial reaction velocity of 1.1 pmol x min-1 x mg-1 protein and intrinsic clearance of 17 ml x min-1 x kg-1.	tizanidine	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	198-203
14998432-4	2004	RESULTS: Incubation of tizanidine (80 nm) with human liver microsomes resulted in time- and NADPH-dependent substrate consumption with a half-life of 50 min, initial reaction velocity of 1.1 pmol x min-1 x mg-1 protein and intrinsic clearance of 17 ml x min-1 x kg-1.	tizanidine	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	254-259
14658015-8	2004	During perindoprilat infusion, myocardial perfusion reserve in patients increased to 3.9+/-0.9 ( P<0.001) due to normalisation of maximal perfusion (2.3+/-0.5 ml min(-1) g(-1), P<0.01).	perindoprilat	7-20	CD59 molecule (CD59 blood group)	Homo sapiens	165-171
15204871-3	2004	For the cases studied, we estimate an average CO(2) generation rate per child as 404 mg/min(-1).	co(2)	46-51	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
15005300-6	2004	Mean bias for oxygen and nitrous oxide uptake was 0.003 l min(-1), for isoflurane 0.0001 l min(-1) and for carbon dioxide 0.001 l min(-1).	Nitrous Oxide	25-38	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
15449549-9	2004	The free water clearance decreased significantly during octreotide administration (3.12 ml/min+/-1.04 SE vs 0.88+/-0.39, p<.03).	Water	9-14	CD59 molecule (CD59 blood group)	Homo sapiens	91-98
15449549-9	2004	The free water clearance decreased significantly during octreotide administration (3.12 ml/min+/-1.04 SE vs 0.88+/-0.39, p<.03).	Octreotide	56-66	CD59 molecule (CD59 blood group)	Homo sapiens	91-98
15033018-0	2004	[CD59 mutation and DNA oxidative damage in A(L) cells induced by crocidolite fibers].	Asbestos, Crocidolite	65-76	CD59 molecule (CD59 blood group)	Homo sapiens	1-5
15033018-6	2004	The mutation frequency of CD59 gene in the group treated with crocidolite and in the presence of DMSO (57 +/- 8) was 72.6% less than that in crocidolite alone treated group.	Asbestos, Crocidolite	62-73	CD59 molecule (CD59 blood group)	Homo sapiens	26-30
15033018-6	2004	The mutation frequency of CD59 gene in the group treated with crocidolite and in the presence of DMSO (57 +/- 8) was 72.6% less than that in crocidolite alone treated group.	Dimethyl Sulfoxide	97-101	CD59 molecule (CD59 blood group)	Homo sapiens	26-30
15033018-6	2004	The mutation frequency of CD59 gene in the group treated with crocidolite and in the presence of DMSO (57 +/- 8) was 72.6% less than that in crocidolite alone treated group.	Asbestos, Crocidolite	141-152	CD59 molecule (CD59 blood group)	Homo sapiens	26-30
14716830-12	2004	The relative activity of S9 fraction of HepG2-CYP2D6*10 metabolized detromethorphan O-demethylation was found to be 2.31 +/- 0.19 nmol/min(-1)/mg(-1) S9 protein (n=3), but was undetectable in parental HepG2 cells.	detromethorphan	68-83	CD59 molecule (CD59 blood group)	Homo sapiens	135-141
14662716-9	2004	A decrease of 42% (2.97+/-0.33 versus 4.75+/-0.47 mL x min(-1) x 100 g tissue(-1), P<0.01) was seen with L-NMMA.	omega-N-Methylarginine	108-114	CD59 molecule (CD59 blood group)	Homo sapiens	55-61
14685005-7	2004	The estimated glomerular filtration rate decreased more slowly in the pimagedine-treated patients with a 36-month decrease from baseline of 6.26 ml/min/1.73 m(2) as compared with 9.80 ml/min/1.73 m(2) in the placebo-treated patients (p = 0.05), and pimagedine reduced the 24-hour total urinary proteinuria.	pimagedine	70-80	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
14685005-7	2004	The estimated glomerular filtration rate decreased more slowly in the pimagedine-treated patients with a 36-month decrease from baseline of 6.26 ml/min/1.73 m(2) as compared with 9.80 ml/min/1.73 m(2) in the placebo-treated patients (p = 0.05), and pimagedine reduced the 24-hour total urinary proteinuria.	pimagedine	70-80	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
14749874-5	2004	Induction of anaesthesia was started with a remifentanil infusion at 0.4 micro g x kg(-1) x min(-1) and 5 min later 2 mg x kg(-1) propofol was given for hypnosis.	Remifentanil	44-56	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
14749879-7	2004	To maintain this neuromuscular blockade, a dose rate of 1.4+/-0.9 micro g x kg(-1) x min(-1) cisatracurium was necessary.	cisatracurium	93-106	CD59 molecule (CD59 blood group)	Homo sapiens	85-91
15000480-1	2004	A propanol-rinsed enzyme preparations (PREP) of papain showed an activity of 59 nmol min(-1) (mg powder)(-1) in tert-butanol at the optimal water activity of 0.2.	1-Propanol	2-10	CD59 molecule (CD59 blood group)	Homo sapiens	85-91
15000480-1	2004	A propanol-rinsed enzyme preparations (PREP) of papain showed an activity of 59 nmol min(-1) (mg powder)(-1) in tert-butanol at the optimal water activity of 0.2.	tert-Butyl Alcohol	112-124	CD59 molecule (CD59 blood group)	Homo sapiens	85-91
15671631-5	2004	iPTP was reduced during PAV (570 +/- 151 cm H(2)O/sec/min(-1), p < 0.01), but not during PSV (727 +/- 116, p = 0.58) compared with unsupported ventilation during exercise (763 +/- 90).	N(6)-(dimethylallyl)adenosine 5'-triphosphate(4-)	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	54-60
18202474-4	2004	All the patients had irreversible levels for creatinine corresponding approximately to a glomerular filtration rate less than 50 ml/min/1.73 m 2 .	Creatinine	45-55	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
14687727-0	2003	Determination of CD59 protein in normal human serum by enzyme immunoassay, using octyl-glucoside detergent to release glycosyl-phosphatidylinositol-CD59 from lipid complex.	octyl-beta-D-glucoside	81-96	CD59 molecule (CD59 blood group)	Homo sapiens	17-21
14687727-0	2003	Determination of CD59 protein in normal human serum by enzyme immunoassay, using octyl-glucoside detergent to release glycosyl-phosphatidylinositol-CD59 from lipid complex.	octyl-beta-D-glucoside	81-96	CD59 molecule (CD59 blood group)	Homo sapiens	148-152
14687727-0	2003	Determination of CD59 protein in normal human serum by enzyme immunoassay, using octyl-glucoside detergent to release glycosyl-phosphatidylinositol-CD59 from lipid complex.	Glycosylphosphatidylinositols	118-147	CD59 molecule (CD59 blood group)	Homo sapiens	17-21
14687727-0	2003	Determination of CD59 protein in normal human serum by enzyme immunoassay, using octyl-glucoside detergent to release glycosyl-phosphatidylinositol-CD59 from lipid complex.	Glycosylphosphatidylinositols	118-147	CD59 molecule (CD59 blood group)	Homo sapiens	148-152
14687727-2	2003	The glycosyl-phosphatidylinositol (GPI)-linked form of CD59 is known to complex with serum high-density lipoprotein.	Glycosylphosphatidylinositols	4-33	CD59 molecule (CD59 blood group)	Homo sapiens	55-59
14687727-2	2003	The glycosyl-phosphatidylinositol (GPI)-linked form of CD59 is known to complex with serum high-density lipoprotein.	Glycosylphosphatidylinositols	35-38	CD59 molecule (CD59 blood group)	Homo sapiens	55-59
14633746-5	2003	Carbon dioxide production (mean (SD)) increased from 92 (21) to 150 (43) ml x min(-1) m(-2) 60-90 min after insufflation and remained increased after the end of insufflation.	Carbon Dioxide	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
14705689-6	2003	Active warming improved thermal comfort and significantly reduced oxygen consumption from 9.7 (4.4) ml x min(-1) x kg(-1) to 5.6 (1.9) ml x min(-1) x kg(-1) (p = 0.038).	Oxygen	66-72	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
14633757-19	2003	midazolam sedation (0.5 mg x min(-1) to a maximum of 5 mg) appears to be as effective as nitrous oxide sedation in 12-16-yr-old healthy paediatric dental patients.	Midazolam	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	29-35
14635045-7	2003	Moreover, engagement of CD59 resulted in tyrosine phosphorylation of CD3zeta chains associated with these NCR, but not those associated with CD16.	Tyrosine	41-49	CD59 molecule (CD59 blood group)	Homo sapiens	24-28
14748459-7	2003	Maximal fat oxidation rates decreased from 0.46 +/- 0.06 to 0.33 +/- 0.06 g min(-1) when carbohydrate was ingested before the start of exercise (P < 0.01).	Carbohydrates	89-101	CD59 molecule (CD59 blood group)	Homo sapiens	76-82
14609517-3	2003	During the TT mean oxygen consumption was 3.79 +/- 0.5 L x min(-1) (83 +/- 5.5% of VO2max) and mean blood lactate was 8.4 +/- 2.4 mM.	Oxygen	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	59-65
14570673-9	2003	s. cm(-5) (dipyridamole 10 microg kg-1x min-1 and 10 ppm NO) (P <0.05 versus NO), and cardiac output increased from 1.93 +/- 0.09 L/min to 2.03 +/- 0.13 L/min and 2.60 +/- 0.30 L/min (P < 0.05 versus NO).	Dipyridamole	11-23	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
14651726-5	2003	RESULTS: Cysteamine was rapidly cleared from the plasma (mean CL/F = 32.3 ml min(-1) kg(-1), range = 17.3-52.2), appeared to be extensively distributed (mean Vss/F = 15.1 l, range 2.7-32.3) and exhibited a mean Tmax of 1.4 h. White blood cell cystine content post-dosing was significantly decreased compared with pre- and post-dose values (average decrement approximately 47%).	Cysteamine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	77-83
14617591-7	2003	This phenylephrine-induced hypertension significantly increased SaO(2) and MD (92.0 +/- 7.5 vs 95.0 +/- 5.0% and 1318 +/- 344 vs 1533 +/- 425 cm x min(-1), respectively).	Phenylephrine	5-18	CD59 molecule (CD59 blood group)	Homo sapiens	147-153
14586387-4	2003	RESULTS: Compared with the air condition, cigarette smoking significantly induced the metabolism of chlorzoxazone (oral clearance, 5.9 +/- 1.5 mL x min(-1) x kg(-1) versus 4.8 +/- 1.0 mL x min(-1) x kg(-1), P <.005) and caffeine (2.0 +/- 0.8 mL x min(-1) x kg(-1) versus 1.5 +/- 0.7 mL x min(-1) x kg(-1), P <.001) but had no effect on caffeine urine metabolite ratios that reflect xanthine oxidase and N-acetyltransferase-2 activity.	Chlorzoxazone	100-113	CD59 molecule (CD59 blood group)	Homo sapiens	148-154
14586387-4	2003	RESULTS: Compared with the air condition, cigarette smoking significantly induced the metabolism of chlorzoxazone (oral clearance, 5.9 +/- 1.5 mL x min(-1) x kg(-1) versus 4.8 +/- 1.0 mL x min(-1) x kg(-1), P <.005) and caffeine (2.0 +/- 0.8 mL x min(-1) x kg(-1) versus 1.5 +/- 0.7 mL x min(-1) x kg(-1), P <.001) but had no effect on caffeine urine metabolite ratios that reflect xanthine oxidase and N-acetyltransferase-2 activity.	Chlorzoxazone	100-113	CD59 molecule (CD59 blood group)	Homo sapiens	189-195
14586387-4	2003	RESULTS: Compared with the air condition, cigarette smoking significantly induced the metabolism of chlorzoxazone (oral clearance, 5.9 +/- 1.5 mL x min(-1) x kg(-1) versus 4.8 +/- 1.0 mL x min(-1) x kg(-1), P <.005) and caffeine (2.0 +/- 0.8 mL x min(-1) x kg(-1) versus 1.5 +/- 0.7 mL x min(-1) x kg(-1), P <.001) but had no effect on caffeine urine metabolite ratios that reflect xanthine oxidase and N-acetyltransferase-2 activity.	Chlorzoxazone	100-113	CD59 molecule (CD59 blood group)	Homo sapiens	189-195
14586387-4	2003	RESULTS: Compared with the air condition, cigarette smoking significantly induced the metabolism of chlorzoxazone (oral clearance, 5.9 +/- 1.5 mL x min(-1) x kg(-1) versus 4.8 +/- 1.0 mL x min(-1) x kg(-1), P <.005) and caffeine (2.0 +/- 0.8 mL x min(-1) x kg(-1) versus 1.5 +/- 0.7 mL x min(-1) x kg(-1), P <.001) but had no effect on caffeine urine metabolite ratios that reflect xanthine oxidase and N-acetyltransferase-2 activity.	Chlorzoxazone	100-113	CD59 molecule (CD59 blood group)	Homo sapiens	189-195
14508692-4	2003	Professional cyclists achieved a maximal oxygen consumption, i.e. VO(2max), of 5.4 (0.5) l x min(-1) [74.6 (2.5) ml x min(-1) x kg(-1), range: 67.8-82.4 ml x min(-1) x kg(-1)] and a maximum power ( W(max)) of 475 (30) W (range: 438-516 W).	Oxygen	41-47	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
14626370-7	2003	Oxygen consumption was 16% greater when running after the graded exercise test (47.9 +/- 5.0 ml x kg(-1) x min(-1); mean+/-s) than when running before it (41.1 +/- 2.7 ml x kg(-1) x min(-1)) (P < 0.05).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
14626370-7	2003	Oxygen consumption was 16% greater when running after the graded exercise test (47.9 +/- 5.0 ml x kg(-1) x min(-1); mean+/-s) than when running before it (41.1 +/- 2.7 ml x kg(-1) x min(-1)) (P < 0.05).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	182-188
15007460-9	2003	At a flow rate of 300 microL min(-1) within the filter region total protein and hemoglobin accessibilities of 4.8% and 7.5% are observed respectively as compared to 1.9% and 3.2% for a filter without nanostructured barbs.	barbs	215-220	CD59 molecule (CD59 blood group)	Homo sapiens	29-35
14565824-3	2003	RibCys (4 or 10 mM), which was present during irradiation and for a few hours after, significantly decreased the yield of CD59- mutants induced by radiation in AL human-hamster hybrid cells.	Aluminum	160-162	CD59 molecule (CD59 blood group)	Homo sapiens	122-126
14601832-8	2003	The response was greatly increased by post-column addition of 1% (v/v) triethylamine and its equivalent amount of formic acid in dichloromethane introduced at 0.1 ml min(-1) into the mobile phase.	triethylamine	71-84	CD59 molecule (CD59 blood group)	Homo sapiens	166-172
14601832-8	2003	The response was greatly increased by post-column addition of 1% (v/v) triethylamine and its equivalent amount of formic acid in dichloromethane introduced at 0.1 ml min(-1) into the mobile phase.	formic acid	114-125	CD59 molecule (CD59 blood group)	Homo sapiens	166-172
14601832-8	2003	The response was greatly increased by post-column addition of 1% (v/v) triethylamine and its equivalent amount of formic acid in dichloromethane introduced at 0.1 ml min(-1) into the mobile phase.	Methylene Chloride	129-144	CD59 molecule (CD59 blood group)	Homo sapiens	166-172
14508314-6	2003	Remifentanil infusion at 2 and 4 microg x kg-1 x min-1 significantly decreased rCBF and mean CBFv.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
14508314-9	2003	100 g-1 x min-1 x mmHg-1 for 2 and 4 microg x kg-1 x min-1 remifentanil, respectively (relative change in percent/mmHg: 1.9 +/- 0.8 and 1.6 +/- 0.5, respectively).	Remifentanil	59-71	CD59 molecule (CD59 blood group)	Homo sapiens	10-58
14508314-10	2003	The average slopes for mean CBFv reactivity were 1.61 +/- 0.95 and 1.54 +/- 0.83 cm x s-1 x mmHg-1 for 2 and 4 microg x kg-1 x min-1 remifentanil, respectively (relative change in percent/mmHg: 1.86 +/- 0.59 and 1.79 +/- 0.59, respectively).	Remifentanil	133-145	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
14508317-4	2003	Then, 2.5 microg x kg-1 x min-1 nitroglycerin liquid nebulized by a 2-l gas flow of 40% oxygen and air mixture was administered to the patients who were diagnosed as having pulmonary hypertension (mean pulmonary arterial pressures > 25 mmHg).	Nitroglycerin	32-45	CD59 molecule (CD59 blood group)	Homo sapiens	26-31
14505791-7	2003	Moreover, the non-renal (mostly hepatic) clearance of levocetirizine is also significantly lower than that of dextrocetirizine (11.8 mL min(-1) vs. 29.2 mL min(-1)).	levocetirizine	54-68	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
12920499-7	2003	The constants of adsorption rate were 0.409 min(-1) for Bi, 0.122 min(-1) for Hg, 0.039 min(-1) for Au, and 0.080 min(-1 )for Pd.	Bismuth	56-58	CD59 molecule (CD59 blood group)	Homo sapiens	44-50
14505791-7	2003	Moreover, the non-renal (mostly hepatic) clearance of levocetirizine is also significantly lower than that of dextrocetirizine (11.8 mL min(-1) vs. 29.2 mL min(-1)).	levocetirizine	54-68	CD59 molecule (CD59 blood group)	Homo sapiens	156-162
14986382-1	2003	Studies on the transportation and flux of various kinds of heavy metals in runoff and sediment of five typical landuse types in West Tiaoxi catchment showed that the losses of Cu (0.21 mg.m-2.min-1), Zn (0.45 mg.m-2.min-1), and Pb (0.15 mg.m-2.min-1) in mulberry and that of Cr (0.06 mg.m-2.min-1) in paddy field were larger in surface runoff, while their losses in pinery were very small.	Copper	176-178	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
12968985-6	2003	A creatinine clearance of 30 ml min(-1) was associated with a decrease in enoxaparin clearance of 27% compared with that in a patient with a median creatinine clearance of 88 ml min-1, and was related to a 1.5- and 3.8-fold increase in the risk of "all" and "major" haemorrhagic episodes, respectively.	Creatinine	2-12	CD59 molecule (CD59 blood group)	Homo sapiens	32-38
12968985-6	2003	A creatinine clearance of 30 ml min(-1) was associated with a decrease in enoxaparin clearance of 27% compared with that in a patient with a median creatinine clearance of 88 ml min-1, and was related to a 1.5- and 3.8-fold increase in the risk of "all" and "major" haemorrhagic episodes, respectively.	Creatinine	2-12	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
12968985-6	2003	A creatinine clearance of 30 ml min(-1) was associated with a decrease in enoxaparin clearance of 27% compared with that in a patient with a median creatinine clearance of 88 ml min-1, and was related to a 1.5- and 3.8-fold increase in the risk of "all" and "major" haemorrhagic episodes, respectively.	Enoxaparin	74-84	CD59 molecule (CD59 blood group)	Homo sapiens	32-38
12968985-6	2003	A creatinine clearance of 30 ml min(-1) was associated with a decrease in enoxaparin clearance of 27% compared with that in a patient with a median creatinine clearance of 88 ml min-1, and was related to a 1.5- and 3.8-fold increase in the risk of "all" and "major" haemorrhagic episodes, respectively.	Enoxaparin	74-84	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
12968985-6	2003	A creatinine clearance of 30 ml min(-1) was associated with a decrease in enoxaparin clearance of 27% compared with that in a patient with a median creatinine clearance of 88 ml min-1, and was related to a 1.5- and 3.8-fold increase in the risk of "all" and "major" haemorrhagic episodes, respectively.	Creatinine	148-158	CD59 molecule (CD59 blood group)	Homo sapiens	32-38
12904196-6	2003	Pain variables were assessed before, during and after intravenous infusions of morphine (10 microg x kg-1 min-1, 10 min), alfentanil (target-controlled infusion, plasma concentration; 60 ng ml-1, 60 min) and ketamine (10 microg x kg-1 min-1, 60 min).	Morphine	79-87	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
12773304-5	2003	After the hot clamp treatment, acetate turnover increased for the two groups and was higher in the group with normal insulin sensitivity: 8.1 +/- 0.7 vs. 5.5 +/- 0.5 micromol x kg-1 x min-1 (P < 0.001).	Acetates	31-38	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
12933413-4	2003	Ketamine was administered with an initial bolus of 0.5 mg/kg followed by a perfusion of 2 micro g x kg(-1) x min(-1) during the first 24 h and 1 micro g x kg(-1) x min(-1) during the following 24 h. The 4-h cumulative morphine doses were measured over 48 h. The VAS scores at rest and at mobilization were measured every 4 h during 48 h. A total of 101 patients were enrolled, and 93 were analyzed (41 in Group K and 52 in Group M).	Ketamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	109-115
12933413-4	2003	Ketamine was administered with an initial bolus of 0.5 mg/kg followed by a perfusion of 2 micro g x kg(-1) x min(-1) during the first 24 h and 1 micro g x kg(-1) x min(-1) during the following 24 h. The 4-h cumulative morphine doses were measured over 48 h. The VAS scores at rest and at mobilization were measured every 4 h during 48 h. A total of 101 patients were enrolled, and 93 were analyzed (41 in Group K and 52 in Group M).	Ketamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	164-170
12960543-4	2003	Images were obtained during infusion of propofol at a rate of 50-80 microg.kg-1.min-1 and after increasing the depth of anesthesia by administering a bolus dose of propofol and increasing the infusion rate to 240 microg.kg-1.min-1.	Propofol	40-48	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
12919178-6	2003	RESULTS: Among men, apparent oral clearance of zolpidem was decreased in elderly compared to young subjects (3.8 vs 11.0 ml min-1 kg-1, P < 0.01), Cmax was increased (93 vs 40 ng ml-1, P < 0.01), and half-life increased (2.7 vs 1.5 h, P < 0.03).	Zolpidem	47-55	CD59 molecule (CD59 blood group)	Homo sapiens	124-134
12919178-7	2003	Among women, zolpidem oral clearance was decreased in the elderly (3.0 vs 5.8 ml min-1 kg-1, P < 0.02), Cmax increased (108 vs 60 ng ml-1, P < 0.001), with no difference in t1/2 (2.3 vs 2.4 h).	Zolpidem	13-21	CD59 molecule (CD59 blood group)	Homo sapiens	81-91
12930438-5	2003	RESULTS: The mean (SD) glomerular filtration rate at the start of COCD was 48 (21) mL/min/1.73 m2, which is currently stable in the five patients continuing treatment.	cocd	66-70	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
12834811-7	2003	Moreover, the transfection of CD59 antisense oligonucleotide into keratinocytes markedly suppressed LPS-induced nuclear translocation of NF-kappaB and cytokine generation.	Oligonucleotides	45-60	CD59 molecule (CD59 blood group)	Homo sapiens	30-34
12909683-6	2003	The major new findings were: (1) CO + normoxia and CO + hyperoxia also elevated MSNA compared to normoxia (63-144 % increase in integrated MSNA; P < 0.05) but they did not increase heart rate (62-67 beats min-1) or ventilation (6.5-6.8 l min-1), and (2) despite the 4-fold elevation in MSNA with hypoxaemia and exercise, resting leg blood flow, vascular conductance and O2 uptake remained unchanged.	Carbon Monoxide	33-37	CD59 molecule (CD59 blood group)	Homo sapiens	241-246
12909683-6	2003	The major new findings were: (1) CO + normoxia and CO + hyperoxia also elevated MSNA compared to normoxia (63-144 % increase in integrated MSNA; P < 0.05) but they did not increase heart rate (62-67 beats min-1) or ventilation (6.5-6.8 l min-1), and (2) despite the 4-fold elevation in MSNA with hypoxaemia and exercise, resting leg blood flow, vascular conductance and O2 uptake remained unchanged.	Carbon Monoxide	33-37	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
12909683-6	2003	The major new findings were: (1) CO + normoxia and CO + hyperoxia also elevated MSNA compared to normoxia (63-144 % increase in integrated MSNA; P < 0.05) but they did not increase heart rate (62-67 beats min-1) or ventilation (6.5-6.8 l min-1), and (2) despite the 4-fold elevation in MSNA with hypoxaemia and exercise, resting leg blood flow, vascular conductance and O2 uptake remained unchanged.	Carbon Monoxide	51-55	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
12909683-6	2003	The major new findings were: (1) CO + normoxia and CO + hyperoxia also elevated MSNA compared to normoxia (63-144 % increase in integrated MSNA; P < 0.05) but they did not increase heart rate (62-67 beats min-1) or ventilation (6.5-6.8 l min-1), and (2) despite the 4-fold elevation in MSNA with hypoxaemia and exercise, resting leg blood flow, vascular conductance and O2 uptake remained unchanged.	Carbon Monoxide	51-55	CD59 molecule (CD59 blood group)	Homo sapiens	241-246
12972865-8	2003	ATVEN of 11.8 +/- 0.3 ml x kg(-1) x min(-1) for HV was significantly higher than SD (8.9 +/- 0.2) and DD (9.2 +/- 0.3).	atven	0-5	CD59 molecule (CD59 blood group)	Homo sapiens	36-42
12972869-5	2003	RESULTS: Compared with peak exercise, dobutamine infusion resulted in lower cardiac output (12 +/- 2 vs 16 +/- 4 l x min(-1), P < 0.0001), heart rates (163 +/- 7 vs 175 +/- 12 beats x min(-1), P < 0.0001), and systolic blood pressure (160 +/- 22 vs 185 +/- 20 mm Hg, P < or = 0.0001).	Dobutamine	38-48	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
12972869-5	2003	RESULTS: Compared with peak exercise, dobutamine infusion resulted in lower cardiac output (12 +/- 2 vs 16 +/- 4 l x min(-1), P < 0.0001), heart rates (163 +/- 7 vs 175 +/- 12 beats x min(-1), P < 0.0001), and systolic blood pressure (160 +/- 22 vs 185 +/- 20 mm Hg, P < or = 0.0001).	Dobutamine	38-48	CD59 molecule (CD59 blood group)	Homo sapiens	187-193
12972882-5	2003	This combination of simultaneous increase in speed and grade yielded a linear work rate and its oxygen uptake response (R2 = 0.96 +/- 0.03) with a slope of 11.4 +/- 2.4 ml x min(-1) x W(-1)-slightly, but significantly, higher than on the cycle (9.6 +/- 2.0 ml x min(-1) x W(-1)).	Oxygen	96-102	CD59 molecule (CD59 blood group)	Homo sapiens	174-180
12972882-5	2003	This combination of simultaneous increase in speed and grade yielded a linear work rate and its oxygen uptake response (R2 = 0.96 +/- 0.03) with a slope of 11.4 +/- 2.4 ml x min(-1) x W(-1)-slightly, but significantly, higher than on the cycle (9.6 +/- 2.0 ml x min(-1) x W(-1)).	Oxygen	96-102	CD59 molecule (CD59 blood group)	Homo sapiens	262-268
12950860-8	2003	Infusion of remifentanil started with a dose of 0.75-1 microg x kg-1x min-1, 1 h before surgery.	Remifentanil	12-24	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
12950982-7	2003	Binding requirement was studied using disaccharides containing either alphagalactosyl or betagalactosyl moieties to inhibit CD59 up-regulation.	Disaccharides	38-51	CD59 molecule (CD59 blood group)	Homo sapiens	124-128
12970913-13	2003	The patient, whose liver volume decreased by 40 % with the CLH below 600 ml x min(-1), would have a higher incidence of postoperative complications.	clh	59-62	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
12902469-3	2003	Triggering CD147 induces a displacement of the GPI-anchored coreceptors CD48 and CD59 from microdomains in human T lymphocytes.	Glycosylphosphatidylinositols	47-50	CD59 molecule (CD59 blood group)	Homo sapiens	81-85
12899620-2	2003	P450 2C5/3LVdH and the related enzyme 2C5dH catalyze the 4"-hydroxylation of diclofenac with apparent K(m) values of 80 and 57 microM and k(cat) values of 13 and 16 min(-1), respectively.	Diclofenac	77-87	CD59 molecule (CD59 blood group)	Homo sapiens	165-171
12885705-8	2003	RESULTS: Phenylalanine net balance (in nmol x min(-1).	Phenylalanine	9-22	CD59 molecule (CD59 blood group)	Homo sapiens	46-52
12944446-7	2003	Mean bias between PA continuous and PA intermittent and Aorta continuous and PA intermittent was 0.15 L x min(-1) (2SD of differences between methods = 1.39 L x min(-1)) and 0.08 L x min(-1) (2SD of differences between methods = 1.43 L x min(-1)).	Protactinium	18-20	CD59 molecule (CD59 blood group)	Homo sapiens	106-112
12898600-1	2003	CD59 (protectin), a phosphatidylinositol-anchored glycoprotein, is a member of the cell membrane-bound complement regulatory proteins that inhibits the formation of the terminal membrane attack complex (MAC) of complement.	Phosphatidylinositols	20-40	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
13677288-5	2003	Dopamine 3-5 micrograms.kg-1.min-1 was administered but occasional ephedrine bolus injection was still necessary.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
12849727-1	2003	The modulations of complement-regulating surface proteins on a human embryonic and a renal carcinoma cell line are described regarding the effects of ochratoxin A and some of its metabolites on the surface markers CD46, CD55 and CD59.	ochratoxin A	150-162	CD59 molecule (CD59 blood group)	Homo sapiens	229-233
15015355-2	2003	METHOD: The HPLC analysis was used to determine shionone directly, using Polaris C18 column and acetonitrile as the mobile phase with a flow rate of 1.0 mL.min-1, and the UV detection wavelength was 200 nm.	shionone	48-56	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
12803598-5	2003	Thirty s after the fentanyl or saline injection, a predetermined dose of 1% propofol was given at a rate of 100 mg min-1.	Propofol	76-84	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
18969094-8	2003	The response time (0-63% of the signal maximum) to a concentration step is 1.2 s for 500 mul injections of 0.1 mmol l(-1) ascorbic acid in acetate buffer at a flow rate of 1 ml min(-1), which corresponds to a response volume of 20 mul.	Ascorbic Acid	122-135	CD59 molecule (CD59 blood group)	Homo sapiens	177-183
12848773-6	2003	RESULTS: Oral coadministration of clarithromycin resulted in a 1.7-fold increase of the area under the digoxin plasma concentration-time curve [mean AUC(0,24) +/- SD 23 +/- 5.2 vs. 14 +/- 2.9 microg x L(-1) x h; 95% confidence interval (CI) on the difference 7.0, 12; P = 0.002] and in a reduction of the nonglomerular renal clearance of digoxin [mean ClRng(0, 24) +/- SD 34 +/- 39 vs. 57 +/- 41 mL min-1; 95% CI on the difference 7.2, 45; P = 0.03].	Clarithromycin	34-48	CD59 molecule (CD59 blood group)	Homo sapiens	399-404
12782026-3	2003	This continuous fluorimetric assay detects activities as low as 0.01 nmol porphyrin consumed min(-1), representing an increase in sensitivity of up to two orders of magnitude over the currently used, discontinuous assays.	Porphyrins	74-83	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
12782026-4	2003	The determination of the steady-state kinetic parameters of ferrochelatase yielded K(m)(PPIX)=1.4+/-0.2 microM, K(m)(Fe(2+))=1.9+/-0.3 microM, and k(cat)=4.0+/-0.3 min(-1).	protoporphyrin IX	88-92	CD59 molecule (CD59 blood group)	Homo sapiens	164-170
12679359-9	2003	microg-1x kg-1x min-1) responses to PE infusion compared with no exercise (9.0 +/- 2.0 PRU x microg-1 kg-1 x min-1 and 10.9 +/- 2.0 mmHg.	Phenylephrine	36-38	CD59 molecule (CD59 blood group)	Homo sapiens	16-21
12730341-8	2003	In fact, a decrease in the carotid-HR response range from 26 +/- 7 beats min-1 at rest to 7 +/- 1 beats min-1 during heavy exercise (P = 0.001) reduced the contribution of Q to the CBR-mediated change in MAP.	q	172-173	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
12730341-8	2003	In fact, a decrease in the carotid-HR response range from 26 +/- 7 beats min-1 at rest to 7 +/- 1 beats min-1 during heavy exercise (P = 0.001) reduced the contribution of Q to the CBR-mediated change in MAP.	q	172-173	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
12766640-3	2003	METHODS: Rocuronium (0.01 mg/kg + 2-10 microg x kg-1 x min-1) was administered to maintain train-of-four (TOF) ratios (assessed every 15 s) of approximately 0.5 and 0.8 over a period of more than 5 min.	Rocuronium	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
12827563-9	2003	Presence of serum creatinine > 1.2 mg/dL at any time before liver transplantation and a baseline GFR <70 mL/min/1.73 m(2) were independent predictors of permanent renal dysfunction.	Creatinine	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
14509702-3	2003	A 90% degradation of a 150-microM EDTA solution with continuous O2-bubbling was shown for the 20-kHz system in approximately 3 h (kpseudo-first order = 1.22 x 10(-2) min-1) and less than 1 h for the 354-kHz system (kpseudo-first order = 5.42 x 10(-2) min-1).	Edetic Acid	34-38	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
14509702-3	2003	A 90% degradation of a 150-microM EDTA solution with continuous O2-bubbling was shown for the 20-kHz system in approximately 3 h (kpseudo-first order = 1.22 x 10(-2) min-1) and less than 1 h for the 354-kHz system (kpseudo-first order = 5.42 x 10(-2) min-1).	Edetic Acid	34-38	CD59 molecule (CD59 blood group)	Homo sapiens	251-256
14509702-3	2003	A 90% degradation of a 150-microM EDTA solution with continuous O2-bubbling was shown for the 20-kHz system in approximately 3 h (kpseudo-first order = 1.22 x 10(-2) min-1) and less than 1 h for the 354-kHz system (kpseudo-first order = 5.42 x 10(-2) min-1).	Oxygen	64-66	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
14509702-3	2003	A 90% degradation of a 150-microM EDTA solution with continuous O2-bubbling was shown for the 20-kHz system in approximately 3 h (kpseudo-first order = 1.22 x 10(-2) min-1) and less than 1 h for the 354-kHz system (kpseudo-first order = 5.42 x 10(-2) min-1).	Oxygen	64-66	CD59 molecule (CD59 blood group)	Homo sapiens	251-256
12866877-5	2003	The optimal gas flows established for the detection of sulfur and phosphorus are in the range of 4 mL min(-1) of oxygen and 9 to 13 mL min(-1) of hydrogen.	Sulfur	55-61	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
12814452-5	2003	In contrast, the free fraction of S-ibuprofen was significantly greater [33%; young 0.48 +/- 0.10%; elderly 0.64 +/- 0.20%] mean difference -0.16; 95% confidence interval (CI) -0.05, -0.27; P < 0.01; and the unbound clearance of the drug enantiomer was significantly lower (28%; young 15.9 +/- 2.2 l min-1; elderly 11.5 +/- 4.1 l min-1; mean difference 4.4; 95% CI 2.12, 6.68; P < 0.001) in the elderly.	Ibuprofen	34-45	CD59 molecule (CD59 blood group)	Homo sapiens	303-308
12866877-5	2003	The optimal gas flows established for the detection of sulfur and phosphorus are in the range of 4 mL min(-1) of oxygen and 9 to 13 mL min(-1) of hydrogen.	Phosphorus	66-76	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
12866877-5	2003	The optimal gas flows established for the detection of sulfur and phosphorus are in the range of 4 mL min(-1) of oxygen and 9 to 13 mL min(-1) of hydrogen.	Hydrogen	146-154	CD59 molecule (CD59 blood group)	Homo sapiens	135-141
12697183-7	2003	Using pure oxygen, an optimal flow rate was observed at 300 ml min(-1), above which reactivity remains essentially constant.	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
12814452-5	2003	In contrast, the free fraction of S-ibuprofen was significantly greater [33%; young 0.48 +/- 0.10%; elderly 0.64 +/- 0.20%] mean difference -0.16; 95% confidence interval (CI) -0.05, -0.27; P < 0.01; and the unbound clearance of the drug enantiomer was significantly lower (28%; young 15.9 +/- 2.2 l min-1; elderly 11.5 +/- 4.1 l min-1; mean difference 4.4; 95% CI 2.12, 6.68; P < 0.001) in the elderly.	Ibuprofen	34-45	CD59 molecule (CD59 blood group)	Homo sapiens	333-338
12853896-5	2003	RESULTS: The results indicated that oxygen consumption (VO2) was significantly higher in the K4b2 compared to the Quark at 80m x min(-1), 0% grade (14.3+/-1.2 vs 13.6+/-1.2ml x kg(-1) x min(-1), respectively), (p<0.01).	Oxygen	36-42	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
12854478-3	2003	Fentanyl 1 microgram.kg-1 was then administered before the start of the operation and infused continuously at a rate of 0.02 microgram.kg-1.min-1 during operation.	Fentanyl	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
12854478-4	2003	Propofol was also infused continuously at 4-10 mg.kg-1.min-1.	Propofol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
12854486-2	2003	We examined the possibility of using the oxygen concentrator, capable of producing 7 l.min-1 of oxygen, for anesthetic circuit.	Oxygen	41-47	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
12854486-2	2003	We examined the possibility of using the oxygen concentrator, capable of producing 7 l.min-1 of oxygen, for anesthetic circuit.	Oxygen	96-102	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
12854486-3	2003	When the oxygen concentrator is connected with an ordinary anesthetic vaporizer, the gas flow from the vaporizer is 6 l.min-1 and its vaporization is the same as when it is used with a high gas pressure.	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
12766604-12	2003	In patients without criteria of glomerular hyperfiltration, plasma level and clearance of creatinine were 128+/-33 micromol.l-1 and 56+/-15 ml.min-1, respectively; and in those patients with glomerular hyperfiltration criteria were 108+/-18 micromol.l-1 (P=NS) and 83+/-24 ml.min-1 (P=0.002) respectively.	Creatinine	90-100	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
12853896-5	2003	RESULTS: The results indicated that oxygen consumption (VO2) was significantly higher in the K4b2 compared to the Quark at 80m x min(-1), 0% grade (14.3+/-1.2 vs 13.6+/-1.2ml x kg(-1) x min(-1), respectively), (p<0.01).	Oxygen	36-42	CD59 molecule (CD59 blood group)	Homo sapiens	186-192
12791116-7	2003	ketamine preincision and a ketamine infusion at 4 micro g.kg-1 min-1 postoperatively.	Ketamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
12853896-6	2003	The fractional concentration of oxygen in expired air was also significantly lower in the K4b2 at 80 m x min(-1), 0% grade and 80 m x min(-1), 10% grade (p<0.05).	Oxygen	32-38	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
12791116-7	2003	ketamine preincision and a ketamine infusion at 4 micro g.kg-1 min-1 postoperatively.	Ketamine	27-35	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
12853896-6	2003	The fractional concentration of oxygen in expired air was also significantly lower in the K4b2 at 80 m x min(-1), 0% grade and 80 m x min(-1), 10% grade (p<0.05).	Oxygen	32-38	CD59 molecule (CD59 blood group)	Homo sapiens	134-140
12791098-8	2003	This suggests that clinical immunotherapy, consisting of treatment with cytokines and MoAb, may induce either up- or downregulation of CD55 or CD59 and thus affect the effectiveness of immunotherapy with MoAb.	Antibodies, Monoclonal	86-90	CD59 molecule (CD59 blood group)	Homo sapiens	143-147
12748750-5	2003	For the DIHEN a nebuliser gas flow rate of 0.3 L min(-1) and 50 mL min(-1) of oxygen added to the plasma auxiliary gas flow gave stable conditions and high analyte sensitivity.	Oxygen	78-84	CD59 molecule (CD59 blood group)	Homo sapiens	67-73
12707242-7	2003	As expected, forearm vascular resistance increased during the cold pressor test, but tyramine produced forearm vasodilation (4.5+/-1 versus -5+/-1 mm Hg x dL(-1) x min(-1), P<0.03) despite the increase in local norepinephrine spillover.	Tyramine	85-93	CD59 molecule (CD59 blood group)	Homo sapiens	164-170
12695357-5	2003	The higher glucuronidation activity was measured with alizarin (125 pmol x min(-1) x mg protein(-1)), whereas UGT2B17 conjugated eugenol, scopoletin, and galangin with glucuronidation rates of 102.5, 102, and 58 pmol x min(-1) x mg protein(-1), respectively.	alizarin	54-62	CD59 molecule (CD59 blood group)	Homo sapiens	75-81
12524381-15	2003	min(-1) at the end of the retraining period in Cr+P (P < 0.05), but it did not change in Cr or Pl.	Pyrilamine	47-51	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
12524381-15	2003	min(-1) at the end of the retraining period in Cr+P (P < 0.05), but it did not change in Cr or Pl.	Chromium	47-49	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
18968997-5	2003	The newly prepared resin quantitatively retained Cr(VI) at pH 2.0-4.0 when the flow rate was maintained between 1 and 5 ml min(-1).	chromium hexavalent ion	49-55	CD59 molecule (CD59 blood group)	Homo sapiens	123-129
12795136-5	2003	In this case, anesthesia was induced with sevoflurane and gradually increased to 5% in oxygen 4 l.min-1 and maintained with sevoflurane 2-3% in 2 nitrous oxide l.min-1 and 2 l.min-1 oxygen.	Sevoflurane	124-135	CD59 molecule (CD59 blood group)	Homo sapiens	162-173
12795136-5	2003	In this case, anesthesia was induced with sevoflurane and gradually increased to 5% in oxygen 4 l.min-1 and maintained with sevoflurane 2-3% in 2 nitrous oxide l.min-1 and 2 l.min-1 oxygen.	Nitrous Oxide	146-159	CD59 molecule (CD59 blood group)	Homo sapiens	162-173
12795136-5	2003	In this case, anesthesia was induced with sevoflurane and gradually increased to 5% in oxygen 4 l.min-1 and maintained with sevoflurane 2-3% in 2 nitrous oxide l.min-1 and 2 l.min-1 oxygen.	Oxygen	182-188	CD59 molecule (CD59 blood group)	Homo sapiens	162-173
12739165-7	2003	Pyruvate and alpha-ketoglutarate dehydrogenase activities (i.e. the tricarboxylic acid cycle turnover) and the respiratory chain activity could all account for ~14 mmol O(2) min(-1) kg(-1) muscle (37 degrees C).	Pyruvic Acid	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	174-180
12739165-7	2003	Pyruvate and alpha-ketoglutarate dehydrogenase activities (i.e. the tricarboxylic acid cycle turnover) and the respiratory chain activity could all account for ~14 mmol O(2) min(-1) kg(-1) muscle (37 degrees C).	Tricarboxylic Acids	68-86	CD59 molecule (CD59 blood group)	Homo sapiens	174-180
12739165-8	2003	The capacity for aerobic ATP synthesis was ~35 mmol ATP min(-1) kg(-1).	Adenosine Triphosphate	25-28	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
12739165-8	2003	The capacity for aerobic ATP synthesis was ~35 mmol ATP min(-1) kg(-1).	Adenosine Triphosphate	52-55	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
12852462-3	2003	Benoxinate was eluted on a 10 microm Spherisorb phenyl column, 250 x 3.2 mm, with a mobile phase consisting of acetonitrile-buffer (pH 3.5) (35:65, v/v), pumped at 0.8 ml min(-1) flow rate.	benoxinate	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	171-177
12684251-7	2003	After approximately 6 months of sildenafil treatment, pulmonary hemodynamics and exercise capacity improved significantly (pulmonary vascular resistance index 1,361 +/- 177 L. min-1.	Sildenafil Citrate	32-42	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
12701897-5	2003	A therapeutic dose rate of 1.7 RBE Gy min(-1) is achievable at the advantage depth of 97 mm when boronated phenylalanine (BPA) is used as the delivery agent, giving an average therapeutic ratio of 5.7.	boronated phenylalanine	97-120	CD59 molecule (CD59 blood group)	Homo sapiens	38-44
12701897-5	2003	A therapeutic dose rate of 1.7 RBE Gy min(-1) is achievable at the advantage depth of 97 mm when boronated phenylalanine (BPA) is used as the delivery agent, giving an average therapeutic ratio of 5.7.	bisphenol A	122-125	CD59 molecule (CD59 blood group)	Homo sapiens	38-44
12488240-9	2003	Glucose infusion, at 3 mg x kg(-1) x min(-1) in P subjects, resulted in a decrease in serine R(a) and an increase in oxidation.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	37-43
12488240-9	2003	Glucose infusion, at 3 mg x kg(-1) x min(-1) in P subjects, resulted in a decrease in serine R(a) and an increase in oxidation.	serine r	86-94	CD59 molecule (CD59 blood group)	Homo sapiens	37-43
12784628-6	2003	The permeation of ferulic acid was concentration-dependent and saturable; the Michaelis constant was 16.2 mM and the maximum velocity was 220.4 nmol min-1 (mg protein)-1.	ferulic acid	18-30	CD59 molecule (CD59 blood group)	Homo sapiens	149-169
12505873-8	2003	Collateral conductance was 645 +/- 346 ml x min(-1) x mmHg(-1) after 2 wk of infusion with PBS, compared with 1,070 +/- 530 and 1,158 +/- 535 ml x min(-1) x mmHg(-1) after 48 h and 2 wk treatment with MCP-1, respectively (P < 0.05).	Lead	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	44-50
12612212-4	2003	Exogenous glucose was administered at a rate of 33 micromol x kg-1 x min-1 followed by 22 micromol x kg-1 x min-1.	Glucose	10-17	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
15321493-7	2003	The median rate of infusion of remifentanil was 0.056 microg.kg(-1) min(-1) [10th-90th centiles: 0.037-0.15 ng.mL(-1)].	Remifentanil	31-43	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
12612212-7	2003	Glucose production rate increased comparably in both groups: < or =30 wk, from 6.0 +/- 4.1 to 8.8 +/- 3.4 micromol x kg-1 x min-1; >30 wk, from 7.8 +/- 4.6 to 11.6 +/- 5.2 micromol x kg-1 x min-1.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
12612212-7	2003	Glucose production rate increased comparably in both groups: < or =30 wk, from 6.0 +/- 4.1 to 8.8 +/- 3.4 micromol x kg-1 x min-1; >30 wk, from 7.8 +/- 4.6 to 11.6 +/- 5.2 micromol x kg-1 x min-1.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	196-201
12668302-7	2003	FINDINGS: By using the Hudson non-rebreathing mask with three valves, increasing the oxygen flow to 15 l min(-1), and fitting the mask tightly to the face the average expired oxygen fraction could be raised to 0.85.	Oxygen	175-181	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
12693793-4	2003	Compared with budesonide alone, change in mean morning and evening peak expiratory flow was greater in the once-daily budesonide/formoterol group (27 and 171 min(-1), respectively; P < 0.001) and twice-daily budesonide/formoterol group (23 and 24 l min(-1), respectively; P < 0.001).	Budesonide	118-128	CD59 molecule (CD59 blood group)	Homo sapiens	158-164
12693793-4	2003	Compared with budesonide alone, change in mean morning and evening peak expiratory flow was greater in the once-daily budesonide/formoterol group (27 and 171 min(-1), respectively; P < 0.001) and twice-daily budesonide/formoterol group (23 and 24 l min(-1), respectively; P < 0.001).	Budesonide	118-128	CD59 molecule (CD59 blood group)	Homo sapiens	252-258
12793050-10	2003	There was a significant increase in the capacity of the transport system expressed by the value of the maximum oxygen uptake (from 1545 +/- 312 to 1740 +/- 359 ml.min-1) and MET (from 5.3 +/- 1.3 to 6.0 +/- 1.4).	Oxygen	111-117	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
12594137-15	2003	In contrast, V*O2-PF systematically overestimated V*O2-Fick in patients by 52 (SD 40) ml min-1 and this bias increased with smaller arteriovenous differences in oxygen content.	o2-pf	15-20	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
12747280-0	2003	Impaired expression of erythrocyte glycosyl-phosphatidylinositol-anchored membrane CD59 in patients with psoriatic arthritis.	Glycosylphosphatidylinositols	35-64	CD59 molecule (CD59 blood group)	Homo sapiens	83-87
12621524-6	2003	Consequently, the systematic increase in CPBV index with increasing pulmonary blood flow between 8.1 and 20 l m2 x min(-1) displays an adaptive response of the cardiopulmonary system by augmenting CPBV (and perhaps pulmonary capillary blood volume through distension and recruitment) to offset the reduction in CPTT, as no significant difference in mean CPTT is observed between these levels of flow (P > 0.05).	cpbv	41-45	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
12603501-8	2003	The date of dialysis was predicted from the least squares linear regression formula and a target serum creatinine level cor- responding to estimated creatinine clearance of 7 mL min-1, at which dialysis was recommended.	Creatinine	103-113	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
12603501-8	2003	The date of dialysis was predicted from the least squares linear regression formula and a target serum creatinine level cor- responding to estimated creatinine clearance of 7 mL min-1, at which dialysis was recommended.	Creatinine	149-159	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
12693793-4	2003	Compared with budesonide alone, change in mean morning and evening peak expiratory flow was greater in the once-daily budesonide/formoterol group (27 and 171 min(-1), respectively; P < 0.001) and twice-daily budesonide/formoterol group (23 and 24 l min(-1), respectively; P < 0.001).	Formoterol Fumarate	129-139	CD59 molecule (CD59 blood group)	Homo sapiens	158-164
12693793-4	2003	Compared with budesonide alone, change in mean morning and evening peak expiratory flow was greater in the once-daily budesonide/formoterol group (27 and 171 min(-1), respectively; P < 0.001) and twice-daily budesonide/formoterol group (23 and 24 l min(-1), respectively; P < 0.001).	Formoterol Fumarate	129-139	CD59 molecule (CD59 blood group)	Homo sapiens	252-258
12693793-4	2003	Compared with budesonide alone, change in mean morning and evening peak expiratory flow was greater in the once-daily budesonide/formoterol group (27 and 171 min(-1), respectively; P < 0.001) and twice-daily budesonide/formoterol group (23 and 24 l min(-1), respectively; P < 0.001).	Budesonide	118-128	CD59 molecule (CD59 blood group)	Homo sapiens	158-164
12693793-4	2003	Compared with budesonide alone, change in mean morning and evening peak expiratory flow was greater in the once-daily budesonide/formoterol group (27 and 171 min(-1), respectively; P < 0.001) and twice-daily budesonide/formoterol group (23 and 24 l min(-1), respectively; P < 0.001).	Budesonide	118-128	CD59 molecule (CD59 blood group)	Homo sapiens	252-258
12825305-11	2003	The only complications were 2 cases of self-limiting sinus tachycardia of less than 130 beats.min-1 in the ephedrine group.	Ephedrine	107-116	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
12540412-7	2003	Acipimox treatment resulted in a significant increase in the insulin sensitivity index (acipimox = 1.63 +/- 0.5 compared with placebo = 0.88 +/- 0.3 x 10(-4) x min(-1) x micro IU/mL, P = 0.015).	acipimox	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	160-166
12792580-8	2003	CONCLUSIONS: Remifentanil analgesia (mean dose of 0.37 microg.kg(-1).min-1) in patients undergoing endonasal endoscopic surgery of the sellar region provides a more efficacious cardiocirculatory control with reduced bleeding and faster psychosensorial recovery.	Remifentanil	13-25	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
12706763-8	2003	RESULTS: Under 10 cmH2O EPAP, the required oxygen flow is < or = 30 l x min(-1).	Oxygen	43-49	CD59 molecule (CD59 blood group)	Homo sapiens	75-81
12625310-1	2003	In a randomised, double-blind study we compared the efficacy of continuous remifentanil infusion (0.25 microg x kg(-1) x min(-1) with 40 mg lidocaine and placebo in the prevention of injection pain due to intravenous propofol administration (1.5-2 mg x kg(-1)) in 155 patients scheduled for elective surgery.	Remifentanil	75-87	CD59 molecule (CD59 blood group)	Homo sapiens	121-127
12706763-9	2003	Measured FIO2 ranges from 70 to 100 vol %, for a volume per minute < or = 15 l x min(-1) except for a EPAP at 2.5 cmH2O with a rate = 10 c min(-1) and a tidal volume (VT) at 1500 ml where the measured FIO2 is 60 vol %.	fio2	9-13	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
12706763-10	2003	For a volume per minute > 15 l x min(-1) and < 20 l x min(-1), measured FIO2 ranges from 59 to 83 vol % depending on the variations of RR and VT.	fio2	78-82	CD59 molecule (CD59 blood group)	Homo sapiens	36-42
12706763-10	2003	For a volume per minute > 15 l x min(-1) and < 20 l x min(-1), measured FIO2 ranges from 59 to 83 vol % depending on the variations of RR and VT.	fio2	78-82	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
12622495-9	2003	The addition of dopamine to the milrinone infusion significantly decreased the heart rate (94 +/- 12 beats min(-1)) and increased the mean arterial pressure (82 +/- 11 mmHg).	Milrinone	32-41	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
12538370-6	2003	RESULTS: The total clearance of ketamine, mean (SD), was 36.0 (13.3) ml min(-1) kg(-1), the volume of distribution (Vbeta) was 16.0 (8.6) litre kg(-1), and the elimination half-life was 4.9 (1.6) h. Ketamine did not alter any haemodynamic variables in the patients studied.	Ketamine	32-40	CD59 molecule (CD59 blood group)	Homo sapiens	72-78
12645951-5	2003	Exosomes express the glycosylphosphatidylinositol (GPI)-anchored regulators CD55 and CD59, but not the transmembrane protein CD46.	Glycosylphosphatidylinositols	21-49	CD59 molecule (CD59 blood group)	Homo sapiens	85-89
12645951-5	2003	Exosomes express the glycosylphosphatidylinositol (GPI)-anchored regulators CD55 and CD59, but not the transmembrane protein CD46.	Glycosylphosphatidylinositols	51-54	CD59 molecule (CD59 blood group)	Homo sapiens	85-89
12666791-6	2003	The response of the photo-sensors is linear with respect to inflowing sulphide concentration, while the most rapid response to dissolved sulphide occurs at a flow rate of approximately 200 ml min(-1) (equivalent to a hydraulic loading rate of 21 cm min(-1).	Sulfides	137-145	CD59 molecule (CD59 blood group)	Homo sapiens	192-198
12666791-10	2003	At the optimal flow rate for the successful use of the cartridge as a sulphide warning system (200 ml min(-1)), required substrate masses for the complete removal of dissolved sulphide (over the experimental range of 0-1000 microM) are relatively small (0.5-2 kg).	Sulfides	70-78	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
12666791-10	2003	At the optimal flow rate for the successful use of the cartridge as a sulphide warning system (200 ml min(-1)), required substrate masses for the complete removal of dissolved sulphide (over the experimental range of 0-1000 microM) are relatively small (0.5-2 kg).	Sulfides	176-184	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
12391094-5	2003	Arm-crank peak oxygen consumption (in ml x kg(-1) x min(-1)) increased by 16% (P < 0.05) after training, and significant differences (P < 0.05) were found in wall thickness (from 0.86 to 0.99 cm) but not in left ventricular internal dimension in diastole or systole.	Oxygen	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	52-58
12531912-6	2003	The ventilatory response to exercise below VTh was 0.35 +/- 0.06 l x min(-1) x W(-1) and above VTh was 0.66 +/- 0.10 l x min(-1) x W(-1).	vth	95-98	CD59 molecule (CD59 blood group)	Homo sapiens	121-127
12531912-8	2003	Inspired CO(2) increased (P < 0.001) the ventilatory response to exercise only below VTh (0.44 +/- 0.10 l x min(-1) x W(-1)).	co(2)	9-14	CD59 molecule (CD59 blood group)	Homo sapiens	111-117
12533533-6	2003	In bPEG-Chol/SA-treated cells, CD59, ganglioside GM1, and clathrin/AP-2 were all accumulated on the surface of the actin-rich extrusion, whereas dynamin and transferrin receptors were unaffected.	bpeg	3-7	CD59 molecule (CD59 blood group)	Homo sapiens	31-35
12533533-6	2003	In bPEG-Chol/SA-treated cells, CD59, ganglioside GM1, and clathrin/AP-2 were all accumulated on the surface of the actin-rich extrusion, whereas dynamin and transferrin receptors were unaffected.	chol	8-12	CD59 molecule (CD59 blood group)	Homo sapiens	31-35
12505938-9	2003	kg(-1) x min(-1) was increased more in the propofol group than in the control group (20 +/- 5 versus 14 +/- 4 bpm; P < 0.05).	Propofol	43-51	CD59 molecule (CD59 blood group)	Homo sapiens	9-15
12622495-6	2003	Dopamine (4 microg kg(-1) min(-1)) was then administered with milrinone.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	26-32
12622495-7	2003	RESULTS: Milrinone significantly increased the heart rate from 81 +/- 8 to 102 +/- 16beats min(-1), but it decreased the mean arterial pressure from 83 +/- 10 to 66 +/- 10 mmHg and systemic vascular resistance (P < 0.05 for each).	Milrinone	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	91-97
12622495-9	2003	The addition of dopamine to the milrinone infusion significantly decreased the heart rate (94 +/- 12 beats min(-1)) and increased the mean arterial pressure (82 +/- 11 mmHg).	Dopamine	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
12482749-7	2003	min(-1), with the latter higher than leucine unidirectional flux and thus supporting a degree of leucine oxidation by the brain.	Leucine	97-104	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
12756965-4	2003	For intubation the RF dosage was 0.26 +/- 0.06 microgram.kg-1.min-1 and the target concentration of P was 3.16 +/- 0.63 micrograms.ml-1.	Remifentanil	19-21	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
12505938-11	2003	kg(-1) x min(-1), HR increased by more than 20 bpm in all patients in the propofol group but in only 31% of patients in the control group (P < 0.0001).	Propofol	74-82	CD59 molecule (CD59 blood group)	Homo sapiens	9-15
12743438-5	2003	With increasing unbound oleic acid concentrations in the medium, LCFA uptake during 5 min of incubation revealed a typical saturation kinetics profile, and exhibiting apparent K(m) values of 3.43 +/- 0.83 microM, and apparent V(max) values of 0.86 +/- 0.07 nmol x min(-1) x mg(-1).	Oleic Acid	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	264-270
12637983-3	2003	On one occasion, plasma glucose was decreased at the rate of 0.1+/-0.003 mmol x min(-1) x l(-1) (fast fall), on the other at the rate of 0.03+/-0.001 mmol x min(-1) x l(-1) (slow fall).	Glucose	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	80-86
14527017-3	2003	Plutonium renal clearance ranged from 110-190 ml min(-1) to 3-4 ml min(-1) at different stages of chelation therapy.	Plutonium	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
12594539-9	2003	Considerable inter-individual variation was observed [e. g. range, mean and standard deviation for rate of hydrolysis of quercetin-3-glucoside (n = 10) were 6.7-456, 96, and 134 nmol min(-1) (mg protein)(-1), respectively].	isoquercitrin	121-142	CD59 molecule (CD59 blood group)	Homo sapiens	183-189
12585337-8	2003	The initial physical condition of these patients was lower than expected, and improved after treatment with an increase in maximum oxygen consumption from 2.0 +/- 1.2 to 2.33 +/- 0.68 l x min(-1) (p = 0.01).	Oxygen	131-137	CD59 molecule (CD59 blood group)	Homo sapiens	188-194
12590385-2	2003	In this method, following an on-line extraction by injection onto a column under TFC conditions, PFOS is back-flushed onto a reversed-phase column via on-line column switching, and resolved chromatographically at a laminar flow rate of 1 mL min(-1).	perfluorooctane sulfonic acid	97-101	CD59 molecule (CD59 blood group)	Homo sapiens	241-247
14527017-3	2003	Plutonium renal clearance ranged from 110-190 ml min(-1) to 3-4 ml min(-1) at different stages of chelation therapy.	Plutonium	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	67-73
12453925-6	2002	RESULTS: The in vitro rate of disappearance of the two active isomers of mivacurium was very rapid, with mean values for the trans trans and cis trans isomers of 0.803 and 0.921 min(-1) respectively.	Mivacurium	73-83	CD59 molecule (CD59 blood group)	Homo sapiens	178-184
12492606-6	2002	RESULTS: While morphine was rapidly cleared from plasma (total clearance = 1838 ml min-1 (95% CI 1668, 2001 ml min-1)) the glucuronide metabolites were eliminated more slowly (clearance M3G = 44.5 ml min-1 (35.1, 53.9 ml min-1), clearance M6G = 42.1 ml min-1 (36.4, 47.7 ml min-1)) and their clearance could be described as a function of creatinine clearance.	Morphine	15-23	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
12492606-6	2002	RESULTS: While morphine was rapidly cleared from plasma (total clearance = 1838 ml min-1 (95% CI 1668, 2001 ml min-1)) the glucuronide metabolites were eliminated more slowly (clearance M3G = 44.5 ml min-1 (35.1, 53.9 ml min-1), clearance M6G = 42.1 ml min-1 (36.4, 47.7 ml min-1)) and their clearance could be described as a function of creatinine clearance.	Morphine	15-23	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
12492606-6	2002	RESULTS: While morphine was rapidly cleared from plasma (total clearance = 1838 ml min-1 (95% CI 1668, 2001 ml min-1)) the glucuronide metabolites were eliminated more slowly (clearance M3G = 44.5 ml min-1 (35.1, 53.9 ml min-1), clearance M6G = 42.1 ml min-1 (36.4, 47.7 ml min-1)) and their clearance could be described as a function of creatinine clearance.	Morphine	15-23	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
12492606-6	2002	RESULTS: While morphine was rapidly cleared from plasma (total clearance = 1838 ml min-1 (95% CI 1668, 2001 ml min-1)) the glucuronide metabolites were eliminated more slowly (clearance M3G = 44.5 ml min-1 (35.1, 53.9 ml min-1), clearance M6G = 42.1 ml min-1 (36.4, 47.7 ml min-1)) and their clearance could be described as a function of creatinine clearance.	Morphine	15-23	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
12492606-6	2002	RESULTS: While morphine was rapidly cleared from plasma (total clearance = 1838 ml min-1 (95% CI 1668, 2001 ml min-1)) the glucuronide metabolites were eliminated more slowly (clearance M3G = 44.5 ml min-1 (35.1, 53.9 ml min-1), clearance M6G = 42.1 ml min-1 (36.4, 47.7 ml min-1)) and their clearance could be described as a function of creatinine clearance.	Morphine	15-23	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
12492606-6	2002	RESULTS: While morphine was rapidly cleared from plasma (total clearance = 1838 ml min-1 (95% CI 1668, 2001 ml min-1)) the glucuronide metabolites were eliminated more slowly (clearance M3G = 44.5 ml min-1 (35.1, 53.9 ml min-1), clearance M6G = 42.1 ml min-1 (36.4, 47.7 ml min-1)) and their clearance could be described as a function of creatinine clearance.	Morphine	15-23	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
12492611-9	2002	The TFPI release rate rapidly increased to maximum of 200 +/- 45 micro g min-1 after 17.5 min heparin infusion but did not increase further although heparin concentrations further doubled.	Heparin	94-101	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
12477685-2	2002	METHODS: Remifentanil infusion was started at 0.02 microg x kg(-1) x min(-1) in ten mechanically ventilated critically-ill patients, and the infusion rate was increased to 0.05, 0.10, 0.15, 0.20, and 0.25 microg x kg(-1) x min(-1) every 30 min.	Remifentanil	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	69-75
12477685-4	2002	RESULTS: Infusion rates up to 0.05 microg x kg(-1) x min(-1) were effective against agitation and achieved a good degree of adaption to the respirator in all patients (RSS 2 or more and CSRR 3 or less); BIS decreased significantly; respiratory and circulatory variables were unaffected; mean plasma epinephrine levels decreased.	RSS	168-171	CD59 molecule (CD59 blood group)	Homo sapiens	53-59
12477685-4	2002	RESULTS: Infusion rates up to 0.05 microg x kg(-1) x min(-1) were effective against agitation and achieved a good degree of adaption to the respirator in all patients (RSS 2 or more and CSRR 3 or less); BIS decreased significantly; respiratory and circulatory variables were unaffected; mean plasma epinephrine levels decreased.	Epinephrine	299-310	CD59 molecule (CD59 blood group)	Homo sapiens	53-59
12477685-5	2002	At infusion rates higher than 0.05 microg x kg(-1) x min(-1) RSS but not BIS decreased further and patient arousability caused by noxious stimuli was not prevented; respiratory drive suppression occurred at the infusion rates higher than 0.05 microg x kg(-1) x min(-1) in four patients; bradycardia and arterial hypotension was observed in three patients; plasma epinephrine levels decreased significantly, while norepinephrine was unaffected; severe itching was experienced by one patient.	RSS	61-64	CD59 molecule (CD59 blood group)	Homo sapiens	53-59
12477685-6	2002	CONCLUSIONS: Low doses of remifentanil (up to 0.05 microg x kg(-1) x min(-1)) can be useful in critically-ill patients in order to achieve calm and sedation.	Remifentanil	26-38	CD59 molecule (CD59 blood group)	Homo sapiens	69-75
12456833-6	2002	Under isosmotic conditions, 1 microl of A6 cells released ATP at a rate of 66 +/- 8 fmol min(-1).	Adenosine Triphosphate	58-61	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
12453906-5	2002	The diabetic donors showed a prominent reduction in the retinal levels of CD55 and CD59, the two complement inhibitors linked to the plasma membrane by glycosylphosphatidylinositol anchors, but not in the levels of transmembrane CD46.	Glycosylphosphatidylinositols	152-180	CD59 molecule (CD59 blood group)	Homo sapiens	83-87
12447527-1	2002	OBJECTIVE: To test whether norepinephrine (NE) infusion at 0.4 microg kg(-1) min(-1) adversely affects regional blood flow in the normal mammalian circulation.	Norepinephrine	27-41	CD59 molecule (CD59 blood group)	Homo sapiens	77-83
12793767-0	2002	Ascorbate, added after irradiation, reduces the mutant yield and alters the spectrum of CD59- mutations in A(L) cells irradiated with high LET carbon ions.	Ascorbic Acid	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	88-92
12793767-3	2002	We here show that post-irradiation treatment with ascorbate (5 mM added 30 min after radiation) reduces, but does not eliminate, the induction of CD59- mutants in human-hamster hybrid A(L) cells exposed to high-LET carbon ions (LET of 100 KeV/microm).	Ascorbic Acid	50-59	CD59 molecule (CD59 blood group)	Homo sapiens	146-150
12793767-6	2002	Preliminary data are presented that ascorbate also alters the spectrum of CD59- mutations induced by the carbon beam, mainly by reducing the incidence of small mutations and mutants displaying transmissible genomic instability (TGI), while large mutations are unaffected.	Ascorbic Acid	36-45	CD59 molecule (CD59 blood group)	Homo sapiens	74-78
12793767-6	2002	Preliminary data are presented that ascorbate also alters the spectrum of CD59- mutations induced by the carbon beam, mainly by reducing the incidence of small mutations and mutants displaying transmissible genomic instability (TGI), while large mutations are unaffected.	Carbon	105-111	CD59 molecule (CD59 blood group)	Homo sapiens	74-78
12471320-7	2002	RESULTS: During treadmill testing, maximal oxygen consumption (VO2max) ranged from of 42.0 to 59.7 mL x kg(-1) x min(-1) (mean +/- SD = 47.6+/-8.1).	Oxygen	43-49	CD59 molecule (CD59 blood group)	Homo sapiens	113-119
12479515-10	2002	RESULTS: For the entire cohort, peak exercise oxygen uptake was 19.9+/-4.8 mL x kg(-1) x min(-1) (61%+/-15% of age and sex predicted).	Oxygen	46-52	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
12456833-7	2002	A sudden reduction of the basolateral osmolality from 260 to 140 mosmol (kg H(2)O)(-1) elevated R(ATP) rapidly to a peak value of 1.89 +/- 0.11 pmol min(-1) (R(ATP)(peak)) followed by a plateau phase reaching 0.51 +/- 0.07 pmol min(-1) (R(ATP)(plat)).	Adenosine Triphosphate	98-101	CD59 molecule (CD59 blood group)	Homo sapiens	149-155
12456833-7	2002	A sudden reduction of the basolateral osmolality from 260 to 140 mosmol (kg H(2)O)(-1) elevated R(ATP) rapidly to a peak value of 1.89 +/- 0.11 pmol min(-1) (R(ATP)(peak)) followed by a plateau phase reaching 0.51 +/- 0.07 pmol min(-1) (R(ATP)(plat)).	Adenosine Triphosphate	98-101	CD59 molecule (CD59 blood group)	Homo sapiens	228-234
12456833-10	2002	Similarly, a steady ATP release of 0.78 +/- 0.08 pmol min(-1) was recorded after gradual dilution of the basolateral osmolality to 140 mosmol (kg H(2)O)(-1).	Adenosine Triphosphate	20-23	CD59 molecule (CD59 blood group)	Homo sapiens	54-60
12444648-5	2002	The first term of this equation is predominant at pH lower than 3.5, in agreement with the literature for the direct nitrosation of thiols with nitrous acid; the value for the third-order rate constant, k(1) = 7.9 x 10(2) L(2) mol(-2) min(-1), was calculated.	Sulfhydryl Compounds	132-138	CD59 molecule (CD59 blood group)	Homo sapiens	235-241
12444648-5	2002	The first term of this equation is predominant at pH lower than 3.5, in agreement with the literature for the direct nitrosation of thiols with nitrous acid; the value for the third-order rate constant, k(1) = 7.9 x 10(2) L(2) mol(-2) min(-1), was calculated.	Nitrous Acid	144-156	CD59 molecule (CD59 blood group)	Homo sapiens	235-241
12456098-3	2002	The mobile phase employed was sulphuric acid solution working at a flow-rate of 0.35 ml min(-1) for the whole run, while methanol was linearly increased to 0.45 ml min(-1) from 15 to 75 min followed by a 5-min isocratic elution.	Methanol	121-129	CD59 molecule (CD59 blood group)	Homo sapiens	164-170
12434244-4	2002	The methods proposed in this paper are based on the transformation of all dissolved vanadium species in seawater into organic complexes by use of synthetic complexing agents such as dithizone, luminol, or 8-hydroxyquinoline; the resulting vanadium-organic complexes were sorbed on to a C(18) column at a flow rate of 5 mL min(-1).	Dithizone	182-191	CD59 molecule (CD59 blood group)	Homo sapiens	322-328
12392499-1	2002	Carbohydrate (CHO) and fat oxidation during exercise at SL were 2.0 +/- 0.2 and 0.3 +/- 0.0 g min(-1), respectively.	Carbohydrates	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	94-100
12434244-4	2002	The methods proposed in this paper are based on the transformation of all dissolved vanadium species in seawater into organic complexes by use of synthetic complexing agents such as dithizone, luminol, or 8-hydroxyquinoline; the resulting vanadium-organic complexes were sorbed on to a C(18) column at a flow rate of 5 mL min(-1).	Luminol	193-200	CD59 molecule (CD59 blood group)	Homo sapiens	322-328
12434244-4	2002	The methods proposed in this paper are based on the transformation of all dissolved vanadium species in seawater into organic complexes by use of synthetic complexing agents such as dithizone, luminol, or 8-hydroxyquinoline; the resulting vanadium-organic complexes were sorbed on to a C(18) column at a flow rate of 5 mL min(-1).	Oxyquinoline	205-223	CD59 molecule (CD59 blood group)	Homo sapiens	322-328
12434244-4	2002	The methods proposed in this paper are based on the transformation of all dissolved vanadium species in seawater into organic complexes by use of synthetic complexing agents such as dithizone, luminol, or 8-hydroxyquinoline; the resulting vanadium-organic complexes were sorbed on to a C(18) column at a flow rate of 5 mL min(-1).	Vanadium	239-247	CD59 molecule (CD59 blood group)	Homo sapiens	322-328
12440986-4	2002	1 min(-1) at 25 degrees C, pH 7.5, and increases proportionally with hydroxide ion concentration between pH 5 and pH 9.	hydroxide ion	69-78	CD59 molecule (CD59 blood group)	Homo sapiens	2-8
12495422-6	2002	ATP dissociation from noncatalytic sites was described by the first order equation for similar sites with a dissociation rate constant kd(ATP) approximately/= 10-3 min-1.	Adenosine Triphosphate	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
12495422-6	2002	ATP dissociation from noncatalytic sites was described by the first order equation for similar sites with a dissociation rate constant kd(ATP) approximately/= 10-3 min-1.	Adenosine Triphosphate	138-141	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
12506986-5	2002	The permeation of fluorescein was concentration-dependent and saturable; the Michaelis constant was 7.7 mM and the maximum velocity was 40.3 nmol min(-1) (mg protein)(-1).	Fluorescein	18-29	CD59 molecule (CD59 blood group)	Homo sapiens	146-152
12449165-7	2002	With MPA/ACET therapy, the hypercapnic and hypoxic ventilatory responses significantly increased, from 3.7 to 5.8 L x min(-1) x kPa(-1) and from -0.13 to -0.40 L x min(-1) x %(-1), respectively.	Medroxyprogesterone Acetate	5-8	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
12494803-8	2002	With the two treatments, PEF increased significantly but no statistical difference were observed between the two groups during the eight hours: 117.7 +/- 41.6 l min-1 to 203.3 +/- 56.9 l min-1 in the salbutamol group; 116.4 +/- 36.8 l min-1 to 217.3 +/- 188.8 l min-1 in the adrenaline group; p = 0.77.	Albuterol	200-210	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
12494803-8	2002	With the two treatments, PEF increased significantly but no statistical difference were observed between the two groups during the eight hours: 117.7 +/- 41.6 l min-1 to 203.3 +/- 56.9 l min-1 in the salbutamol group; 116.4 +/- 36.8 l min-1 to 217.3 +/- 188.8 l min-1 in the adrenaline group; p = 0.77.	Albuterol	200-210	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
12494803-8	2002	With the two treatments, PEF increased significantly but no statistical difference were observed between the two groups during the eight hours: 117.7 +/- 41.6 l min-1 to 203.3 +/- 56.9 l min-1 in the salbutamol group; 116.4 +/- 36.8 l min-1 to 217.3 +/- 188.8 l min-1 in the adrenaline group; p = 0.77.	Albuterol	200-210	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
12385028-6	2002	By contrast, in the same conditions, Ca2+ signaling via the glycosylphosphatidylinositol (GPI)-anchored protein CD59 is totally abolished.	Glycosylphosphatidylinositols	60-88	CD59 molecule (CD59 blood group)	Homo sapiens	112-116
12385028-6	2002	By contrast, in the same conditions, Ca2+ signaling via the glycosylphosphatidylinositol (GPI)-anchored protein CD59 is totally abolished.	Glycosylphosphatidylinositols	90-93	CD59 molecule (CD59 blood group)	Homo sapiens	112-116
12449165-7	2002	With MPA/ACET therapy, the hypercapnic and hypoxic ventilatory responses significantly increased, from 3.7 to 5.8 L x min(-1) x kPa(-1) and from -0.13 to -0.40 L x min(-1) x %(-1), respectively.	Medroxyprogesterone Acetate	5-8	CD59 molecule (CD59 blood group)	Homo sapiens	164-170
12449165-7	2002	With MPA/ACET therapy, the hypercapnic and hypoxic ventilatory responses significantly increased, from 3.7 to 5.8 L x min(-1) x kPa(-1) and from -0.13 to -0.40 L x min(-1) x %(-1), respectively.	Acetazolamide	9-13	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
12449165-7	2002	With MPA/ACET therapy, the hypercapnic and hypoxic ventilatory responses significantly increased, from 3.7 to 5.8 L x min(-1) x kPa(-1) and from -0.13 to -0.40 L x min(-1) x %(-1), respectively.	Acetazolamide	9-13	CD59 molecule (CD59 blood group)	Homo sapiens	164-170
12683006-2	2002	Separations were performed on a YWG-C18 column using a mobile phase of 0.01 mol.L-1 sodium acetate-acetic acid buffer at pH 5.5 at a flow rate of 0.8 mL.min-1.	Sodium Acetate	84-98	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
12381192-4	2002	The enzyme that cleaves an L-ribonucleotide is about 10-fold slower and has a catalytic efficiency of approximately 4 x 10(5) M(-1) min(-1).	l-ribonucleotide	27-43	CD59 molecule (CD59 blood group)	Homo sapiens	132-138
12413255-1	2002	After institutional approval and with written informed consent, eight surgical patients were infused intravenously with remifentanil at 250 ngkg lean body mass (LBM)(-1) x min(-1) for 30 min.	Remifentanil	120-132	CD59 molecule (CD59 blood group)	Homo sapiens	172-178
12370246-6	2002	Depletion of endogenous MAL2 drastically blocked transcytotic transport of exogenous polymeric immunoglobulin receptor and endogenous glycosylphosphatidylinositol-anchored protein CD59 to the apical membrane.	Glycosylphosphatidylinositols	134-162	CD59 molecule (CD59 blood group)	Homo sapiens	180-184
12239154-2	2002	PRV-1 is a member of the uPAR/CD59/Ly6 family of cell surface receptors, which share a common cysteine-rich domain and are tethered to the cell surface via a glycosylphosphatidylinositol (GPI) link.	Cysteine	94-102	CD59 molecule (CD59 blood group)	Homo sapiens	30-34
12239154-2	2002	PRV-1 is a member of the uPAR/CD59/Ly6 family of cell surface receptors, which share a common cysteine-rich domain and are tethered to the cell surface via a glycosylphosphatidylinositol (GPI) link.	Glycosylphosphatidylinositols	158-186	CD59 molecule (CD59 blood group)	Homo sapiens	30-34
12239154-2	2002	PRV-1 is a member of the uPAR/CD59/Ly6 family of cell surface receptors, which share a common cysteine-rich domain and are tethered to the cell surface via a glycosylphosphatidylinositol (GPI) link.	Glycosylphosphatidylinositols	188-191	CD59 molecule (CD59 blood group)	Homo sapiens	30-34
12392582-19	2002	midazolam were 4.4 +/- 1.0 ml min-1 kg-1 and 1.1 +/- 0.2 l kg-1 (mean +/- s.d.	Midazolam	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	30-48
12455322-1	2002	We describe the cases of 3 patients who received anesthesia with remifentanil continuously infused at rates of 0.8 to 1.25 micrograms.kg-1.min-1 for at least 3 hours.	Remifentanil	65-77	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
12361925-9	2002	Mutation spectrum analysis showed that the types of CD59(-) mutants induced by crocidolite fibers were similar to those induced by equitoxic doses of H(2)O(2).	Asbestos, Crocidolite	79-90	CD59 molecule (CD59 blood group)	Homo sapiens	52-56
12412676-7	2002	Statistically greater increases in cardiac frequency (2.6 beats x min(-1), p=0.03) were found on terbutaline.	Terbutaline	97-108	CD59 molecule (CD59 blood group)	Homo sapiens	66-72
12455322-2	2002	Upon emergence from anesthesia, after withdrawal of the anesthetic gas, satisfactory levels of consciousness, spontaneous breathing and absence of pain were achieved under maintenance doses of remifentanil greater than 0.8 microgram.kg-1.min-1; such doses are related to the development of ventilatory depression, apnea and significant sedation.	Remifentanil	193-205	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
12167566-13	2002	Alpha-DHA-G was formed in incubations of DHA with expressed UGT1A9 (K(m) 32 microM, V(max) 8.9 pmol min(-1) mg(-1)) or UGT2B7 (K(m) 438 microM, V(max) 10.9 pmol mg(-1) min(-1)) but not with UGT1A1 or UGT1A6.	artenimol	6-9	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
12167566-13	2002	Alpha-DHA-G was formed in incubations of DHA with expressed UGT1A9 (K(m) 32 microM, V(max) 8.9 pmol min(-1) mg(-1)) or UGT2B7 (K(m) 438 microM, V(max) 10.9 pmol mg(-1) min(-1)) but not with UGT1A1 or UGT1A6.	artenimol	6-9	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
12208222-3	2002	METHODS AND RESULTS: Levosimendan at different doses (0.1-0.4 microg x kg(-1) x min(-1)) or placebo were administered intravenously for 6h to 504 patients in a randomised, placebo-controlled, double-blind study.	Simendan	21-33	CD59 molecule (CD59 blood group)	Homo sapiens	80-86
12208222-10	2002	CONCLUSION: s Levosimendan at doses 0.1-0.2 microg x kg(-1) x min(-1) did not induce hypotension or ischaemia and reduced the risk of worsening heart failure and death in patients with left ventricular failure complicating acute myocardial infarction.	Simendan	14-26	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
12369738-8	2002	But, generation of the same external mechanical power output at 120 rev min(-1) causes more stepper increase (p < 0.01) in the plasma growth hormone concentration [GH]pl and plasma lactate concentrations [La]pl when compared to that observed during cycling at 60 rev x min(-1).	Lactic Acid	184-191	CD59 molecule (CD59 blood group)	Homo sapiens	72-78
12145072-18	2002	min(-1) for propofol.	Propofol	12-20	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
12167566-12	2002	In human liver microsomal incubations, DHA-G (diastereomer unspecified) was the only metabolite found (V(max) 177 +/- 47 pmol min(-1) mg(-1), K(m) 90 +/- 16 microM).	dha-g	39-44	CD59 molecule (CD59 blood group)	Homo sapiens	126-132
12167566-13	2002	Alpha-DHA-G was formed in incubations of DHA with expressed UGT1A9 (K(m) 32 microM, V(max) 8.9 pmol min(-1) mg(-1)) or UGT2B7 (K(m) 438 microM, V(max) 10.9 pmol mg(-1) min(-1)) but not with UGT1A1 or UGT1A6.	alpha-dha-g	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
12167566-13	2002	Alpha-DHA-G was formed in incubations of DHA with expressed UGT1A9 (K(m) 32 microM, V(max) 8.9 pmol min(-1) mg(-1)) or UGT2B7 (K(m) 438 microM, V(max) 10.9 pmol mg(-1) min(-1)) but not with UGT1A1 or UGT1A6.	alpha-dha-g	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
12212959-6	2002	Pa,O2 increased to acceptable levels with an O2 supply of 2 L x min(-1) at rest and 4 L x min(-1) during 20 W exercise.	Protactinium	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	64-70
12212959-6	2002	Pa,O2 increased to acceptable levels with an O2 supply of 2 L x min(-1) at rest and 4 L x min(-1) during 20 W exercise.	Protactinium	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
12212959-6	2002	Pa,O2 increased to acceptable levels with an O2 supply of 2 L x min(-1) at rest and 4 L x min(-1) during 20 W exercise.	Oxygen	3-5	CD59 molecule (CD59 blood group)	Homo sapiens	64-70
12212959-6	2002	Pa,O2 increased to acceptable levels with an O2 supply of 2 L x min(-1) at rest and 4 L x min(-1) during 20 W exercise.	Oxygen	3-5	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
12212959-6	2002	Pa,O2 increased to acceptable levels with an O2 supply of 2 L x min(-1) at rest and 4 L x min(-1) during 20 W exercise.	Oxygen	45-47	CD59 molecule (CD59 blood group)	Homo sapiens	64-70
12196004-3	2002	The reported NO2 absorption efficiency of the method of 82% at a flow rate of 0.2 l min-1 was found to be as low as 33% at a flow rate of 1.0 l min-1 for a sampling duration of 24 h. Similarly, a considerable decrease in absorption efficiency with increasing sampling duration from 2 to 24 h was observed at a particular flow rate.	Nitrogen Dioxide	13-16	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
12296989-5	2002	The oral clearance of (S)-ibuprofen was significantly greater than that of the R-enantiomer (74.5 +/- 18.1 versus 57.1 +/- 11.7 ml min(-1); p < 0.05) and the clearance of (R)-ibuprofen via inversion was ca two fold that via alternative pathways.	Ibuprofen	22-35	CD59 molecule (CD59 blood group)	Homo sapiens	131-137
12147561-11	2002	Peak oxygen uptake increased from 18.1 to 19.7 ml x kg(-1) x min(-1) in the strength and from 17.1 to 18.2 in the endurance group (non-significant).	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	61-67
12131112-14	2002	CONCLUSIONS: Amrinone at an infusion rate of 15 or 5 microg x kg(-1) x min(-1) with a reloading at the beginning of rewarming accelerated the rewarming rate of core temperature during deliberate mild hypothermia.	Amrinone	13-21	CD59 molecule (CD59 blood group)	Homo sapiens	71-77
12402447-3	2002	The duration of the exercise for the children in the obesity group was significantly shorter than controls (P = 0.010) but obese children have greater absolute values for oxygen uptake (VO2peak ml min-1 = 1907 +/- 671 versus 1495 +/- 562; P = 0.013) and ventilatory variables (VE, VT), which adjusted for body mass decrease significantly (VO2/kg ml min-1 kg-1 = 29.2 +/- 3.8 versus 33.6 +/- 3.5; P < 0.001).	Oxygen	171-177	CD59 molecule (CD59 blood group)	Homo sapiens	197-202
12402449-6	2002	All participants were studied during a 150-min basal period followed by a 120-min infusion of 16 mumol kg-1 min-1 13C-labelled glycerol.	13c	114-117	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
12402449-6	2002	All participants were studied during a 150-min basal period followed by a 120-min infusion of 16 mumol kg-1 min-1 13C-labelled glycerol.	Glycerol	127-135	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
12402451-5	2002	However, the higher value in HRVI was found in group A. Maximal oxygen consumption (VO2max) was 62.0 +/- 4.4 ml kg-1 min-1 in group A, 52.7 +/- 6.0 in group B, 44.6 +/- 5.3 in C and 41.6 +/- 6.0 in D. The higher value in VO2max was also found in group A.	Oxygen	64-70	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
12135486-6	2002	The GST-fused forms of NBD1 and NBD2 hydrolyzed ATP with an apparent K(m) of 340 microm and a V(max) of 6.0 nmol P(I) x mg-1 x min-1, and a K(m) of 910 microm ATP and a V(max) of 7.5 nmol P(I) x mg-1 x min-1, respectively.	Adenosine Triphosphate	48-51	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
12135486-6	2002	The GST-fused forms of NBD1 and NBD2 hydrolyzed ATP with an apparent K(m) of 340 microm and a V(max) of 6.0 nmol P(I) x mg-1 x min-1, and a K(m) of 910 microm ATP and a V(max) of 7.5 nmol P(I) x mg-1 x min-1, respectively.	Adenosine Triphosphate	48-51	CD59 molecule (CD59 blood group)	Homo sapiens	202-207
12077725-4	2002	At 33 micromol x kg(-1) x min(-1) of galactose alone (1) plasma galactose increased to 2.3 +/- 0.3 mmol/L and galactose rates of appearance (Ra) to 18.3 +/- 1.6 micromol x kg(-1) x min(-1); (2) plasma glucose and glucose Ra were unaffected; (3) splanchnic extraction of galactose plateaued at approximately 15 micromol x kg(-1) x min(-1); and (4) galactose became the primary source of glucose Ra (75% +/- 9%).	Galactose	37-46	CD59 molecule (CD59 blood group)	Homo sapiens	26-32
12077725-4	2002	At 33 micromol x kg(-1) x min(-1) of galactose alone (1) plasma galactose increased to 2.3 +/- 0.3 mmol/L and galactose rates of appearance (Ra) to 18.3 +/- 1.6 micromol x kg(-1) x min(-1); (2) plasma glucose and glucose Ra were unaffected; (3) splanchnic extraction of galactose plateaued at approximately 15 micromol x kg(-1) x min(-1); and (4) galactose became the primary source of glucose Ra (75% +/- 9%).	Galactose	37-46	CD59 molecule (CD59 blood group)	Homo sapiens	181-187
12077725-4	2002	At 33 micromol x kg(-1) x min(-1) of galactose alone (1) plasma galactose increased to 2.3 +/- 0.3 mmol/L and galactose rates of appearance (Ra) to 18.3 +/- 1.6 micromol x kg(-1) x min(-1); (2) plasma glucose and glucose Ra were unaffected; (3) splanchnic extraction of galactose plateaued at approximately 15 micromol x kg(-1) x min(-1); and (4) galactose became the primary source of glucose Ra (75% +/- 9%).	Galactose	37-46	CD59 molecule (CD59 blood group)	Homo sapiens	181-187
12077725-5	2002	Coingestion of glucose and galactose at 33 micromol x kg(-1) x min(-1) each resulted in (1) decreased plasma galactose (0.3 +/- 0.1 mmol/L) and galactose Ra (6.4 +/- 1.8 micromol x kg(-1) x min(-1)); (2) increased plasma glucose and insulin; (3) doubling of splanchnic extraction of galactose; and (4) decreased contribution of galactose to glucose Ra (11% +/- 4%).	Glucose	15-22	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
12077725-5	2002	Coingestion of glucose and galactose at 33 micromol x kg(-1) x min(-1) each resulted in (1) decreased plasma galactose (0.3 +/- 0.1 mmol/L) and galactose Ra (6.4 +/- 1.8 micromol x kg(-1) x min(-1)); (2) increased plasma glucose and insulin; (3) doubling of splanchnic extraction of galactose; and (4) decreased contribution of galactose to glucose Ra (11% +/- 4%).	Glucose	15-22	CD59 molecule (CD59 blood group)	Homo sapiens	190-196
12077725-5	2002	Coingestion of glucose and galactose at 33 micromol x kg(-1) x min(-1) each resulted in (1) decreased plasma galactose (0.3 +/- 0.1 mmol/L) and galactose Ra (6.4 +/- 1.8 micromol x kg(-1) x min(-1)); (2) increased plasma glucose and insulin; (3) doubling of splanchnic extraction of galactose; and (4) decreased contribution of galactose to glucose Ra (11% +/- 4%).	Galactose	27-36	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
12077725-5	2002	Coingestion of glucose and galactose at 33 micromol x kg(-1) x min(-1) each resulted in (1) decreased plasma galactose (0.3 +/- 0.1 mmol/L) and galactose Ra (6.4 +/- 1.8 micromol x kg(-1) x min(-1)); (2) increased plasma glucose and insulin; (3) doubling of splanchnic extraction of galactose; and (4) decreased contribution of galactose to glucose Ra (11% +/- 4%).	Galactose	27-36	CD59 molecule (CD59 blood group)	Homo sapiens	190-196
12077725-5	2002	Coingestion of glucose and galactose at 33 micromol x kg(-1) x min(-1) each resulted in (1) decreased plasma galactose (0.3 +/- 0.1 mmol/L) and galactose Ra (6.4 +/- 1.8 micromol x kg(-1) x min(-1)); (2) increased plasma glucose and insulin; (3) doubling of splanchnic extraction of galactose; and (4) decreased contribution of galactose to glucose Ra (11% +/- 4%).	Galactose	109-118	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
12077725-5	2002	Coingestion of glucose and galactose at 33 micromol x kg(-1) x min(-1) each resulted in (1) decreased plasma galactose (0.3 +/- 0.1 mmol/L) and galactose Ra (6.4 +/- 1.8 micromol x kg(-1) x min(-1)); (2) increased plasma glucose and insulin; (3) doubling of splanchnic extraction of galactose; and (4) decreased contribution of galactose to glucose Ra (11% +/- 4%).	Glucose	221-228	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
12077725-5	2002	Coingestion of glucose and galactose at 33 micromol x kg(-1) x min(-1) each resulted in (1) decreased plasma galactose (0.3 +/- 0.1 mmol/L) and galactose Ra (6.4 +/- 1.8 micromol x kg(-1) x min(-1)); (2) increased plasma glucose and insulin; (3) doubling of splanchnic extraction of galactose; and (4) decreased contribution of galactose to glucose Ra (11% +/- 4%).	Galactose	109-118	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
12084857-5	2002	Vincristine clearance was substantially slower than has been reported previously for children receiving vincristine in combination with steroids as part of combination chemotherapy (median clearance, 228 mL.min(-1).m(-2) versus mean clearance, 381 and 482 mL.	Vincristine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	207-213
12095139-6	2002	Splanchnic oxygen consumption increased in cardiac surgery patients from 39 (5) mL x min(-1) x m(-2) to 46 (6) mL x min(-1) x m(-2) (P = 0.003) but decreased in septic patients from 61 (19) mL x min(-1) x m(-2) to 51 (17) L x min(-1) x m(-2) (p = 0.021).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	85-91
12095139-6	2002	Splanchnic oxygen consumption increased in cardiac surgery patients from 39 (5) mL x min(-1) x m(-2) to 46 (6) mL x min(-1) x m(-2) (P = 0.003) but decreased in septic patients from 61 (19) mL x min(-1) x m(-2) to 51 (17) L x min(-1) x m(-2) (p = 0.021).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
12095139-6	2002	Splanchnic oxygen consumption increased in cardiac surgery patients from 39 (5) mL x min(-1) x m(-2) to 46 (6) mL x min(-1) x m(-2) (P = 0.003) but decreased in septic patients from 61 (19) mL x min(-1) x m(-2) to 51 (17) L x min(-1) x m(-2) (p = 0.021).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
12111177-8	2002	Preoperative creatinine clearances in the normal, temporary, and persistent groups were 94.25+/-27.47, 95.19+/-18.63, and 69.18+/-16.18 ml/min/1.73 m(2), respectively, being significantly lower in the persistent group ( P<0.05).	Creatinine	13-23	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
12111177-9	2002	In this group, patients with creatinine clearances less than 70 ml/min/1.73 m(2) could not compensate for metabolic acidosis.	Creatinine	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
12162852-4	2002	An assay was set up to study the sulfation of 7-OH-flavone, and using this assay, it was observed that 7-OH-flavone was sulfated and the rate of sulfation (mean +/- SD) was 324 +/- 87 pmol min(-1) mg(-1) (liver) and 584 +/- 164 pmol min(-1) mg(-1) (duodenum; p < 0.0001).	7-oh-flavone	46-58	CD59 molecule (CD59 blood group)	Homo sapiens	189-195
12162852-4	2002	An assay was set up to study the sulfation of 7-OH-flavone, and using this assay, it was observed that 7-OH-flavone was sulfated and the rate of sulfation (mean +/- SD) was 324 +/- 87 pmol min(-1) mg(-1) (liver) and 584 +/- 164 pmol min(-1) mg(-1) (duodenum; p < 0.0001).	7-oh-flavone	46-58	CD59 molecule (CD59 blood group)	Homo sapiens	233-239
12162852-4	2002	An assay was set up to study the sulfation of 7-OH-flavone, and using this assay, it was observed that 7-OH-flavone was sulfated and the rate of sulfation (mean +/- SD) was 324 +/- 87 pmol min(-1) mg(-1) (liver) and 584 +/- 164 pmol min(-1) mg(-1) (duodenum; p < 0.0001).	7-oh-flavone	103-115	CD59 molecule (CD59 blood group)	Homo sapiens	189-195
12162852-4	2002	An assay was set up to study the sulfation of 7-OH-flavone, and using this assay, it was observed that 7-OH-flavone was sulfated and the rate of sulfation (mean +/- SD) was 324 +/- 87 pmol min(-1) mg(-1) (liver) and 584 +/- 164 pmol min(-1) mg(-1) (duodenum; p < 0.0001).	7-oh-flavone	103-115	CD59 molecule (CD59 blood group)	Homo sapiens	233-239
12162854-8	2002	The rate of apomorphine sulfation (mean +/- SD and median) was 261 +/- 82 and 242 pmol min(-1) mg(-1), respectively (liver), and 433 +/- 157 and 443 pmol min(-1) mg(-1), respectively (duodenum).	Apomorphine	12-23	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
12116342-6	2002	This latter procedure allowed for the simultaneous analysis of CD55 and CD59 expression on red cells, platelets, neutrophils, monocytes, and lymphocytes present in the sample through the combined staining of CD55 and CD59 with CD64-fluorescein isothiocyante (FITC) plus CD61-peridinin chlorophyll protein (PerCP) and CD45-PerCP.	fluorescein isothiocyante	232-257	CD59 molecule (CD59 blood group)	Homo sapiens	217-221
12027446-2	2002	In addition, HIV particles and nucleolin coaggregate with glycolipid-enriched membrane microdomains (GEMs) containing ganglioside, and glycosylphosphatidylinositol-linked proteins CD90 and CD59, pointing out that HIV anchorage induces lateral assemblies of specific membrane components into lipid rafts in which surface nucleolin is also incorporated.	Glycolipids	58-68	CD59 molecule (CD59 blood group)	Homo sapiens	189-193
12003831-2	2002	Maximum oxygen uptake increased from 46 +/- 6 to 54 +/- 5 ml x kg(-1) x min(-1) (P = 0.04), maximum ergometric workload changed from 3.8 +/- 0.3 to 4.4 +/- 0.3 W/kg (P = 0.001), and left ventricular mass index increased from 82 +/- 18 to 108 +/- 29 g/m(2) (P = 0.001).	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	72-78
12083551-4	2002	A flow rate of 1.15 ml min(-1) at a column temperature of 43.5 degrees C using 63.7% methanol in water gave the most efficient separation.	Methanol	85-93	CD59 molecule (CD59 blood group)	Homo sapiens	23-29
12083551-4	2002	A flow rate of 1.15 ml min(-1) at a column temperature of 43.5 degrees C using 63.7% methanol in water gave the most efficient separation.	Water	97-102	CD59 molecule (CD59 blood group)	Homo sapiens	23-29
12079941-2	2002	Heparin-coated circuits with a centrifugal pump provided 2.5 to 3.5 L x min(-1) of flow to maintain good hemodynamics and enable easy access to the posterior vessels during vertical displacement of the heart.	Heparin	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	72-78
12069449-4	2002	RESULTS: Cox proportional-hazards model demonstrated that the unadjusted risk ratio associated with a calculated creatinine clearance < or =40 ml x min(-1) compared to a clearance above 85 ml x min(-1) was 7.1 (95% confidence interval 6.2-8.0).	Creatinine	113-123	CD59 molecule (CD59 blood group)	Homo sapiens	151-157
12069449-4	2002	RESULTS: Cox proportional-hazards model demonstrated that the unadjusted risk ratio associated with a calculated creatinine clearance < or =40 ml x min(-1) compared to a clearance above 85 ml x min(-1) was 7.1 (95% confidence interval 6.2-8.0).	Creatinine	113-123	CD59 molecule (CD59 blood group)	Homo sapiens	197-203
12078996-8	2002	However, fetal placental clearance (CLpl) of indometacin (10.0+/-2.5 mL min(-1) kg(-1), n = 10) averaged 115.1+/-41.2% of TBC in these animals and the calculated value for fetal non-placental clearance (0.6+/-2.8 mL min(-1) kg(-1)) was not significantly different from zero.	Indomethacin	45-56	CD59 molecule (CD59 blood group)	Homo sapiens	72-78
12078996-9	2002	Fetal renal clearance of intact indometacin (3.8+/-1.1 microL min(-1) kg(-1); n = 12) was also very low.	Indomethacin	32-43	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
12054528-3	2002	Here we report the construction and expression of a fluorescent GPI anchor on the surface of CHO, EL4, and U937 cells by fusing green fluorescent protein (GFP) to the GPI-attachment site of CD59.	Glycosylphosphatidylinositols	64-67	CD59 molecule (CD59 blood group)	Homo sapiens	190-194
12054528-3	2002	Here we report the construction and expression of a fluorescent GPI anchor on the surface of CHO, EL4, and U937 cells by fusing green fluorescent protein (GFP) to the GPI-attachment site of CD59.	CAV protocol	93-96	CD59 molecule (CD59 blood group)	Homo sapiens	190-194
12054528-3	2002	Here we report the construction and expression of a fluorescent GPI anchor on the surface of CHO, EL4, and U937 cells by fusing green fluorescent protein (GFP) to the GPI-attachment site of CD59.	Glycosylphosphatidylinositols	167-170	CD59 molecule (CD59 blood group)	Homo sapiens	190-194
11959654-5	2002	Demand-induced ischemia was produced with intravenous dobutamine (15 microg x kg(-1) x min(-1)) and 20% reduction in LAD flow for 20 min.	Dobutamine	54-64	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
12012076-8	2002	The average rates of oxygen consumption over the entire immersion period were lower ( P=0.002) during M [0.93 (0.20) l x min(-1)] compared to H [1.05 (0.21) l x min(-1)), and while these rates did not change during the last 90 min of immersion, there was an increase in fat oxidation.	Oxygen	21-27	CD59 molecule (CD59 blood group)	Homo sapiens	121-127
11960953-9	2002	The dose-response curves to ACh were similar in patients and controls, with maximum values of 19.3 +/- 4.4 vs. 25.5 +/- 2.8 ml x dl-1 x min-1, respectively.	Acetylcholine	28-31	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
11960953-10	2002	L-NMMA reduced baseline FBF similarly and reduced the maximal FBF response to ACh in both groups (patients 8.9 +/- 3.5 vs. controls 9.7 +/- 2.5 ml x dl-1 x min-1).	omega-N-Methylarginine	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
11960963-3	2002	Isoproterenol (0.75-24 ng x 100 ml limb volume-1 x min-1) and phenylephrine (0.025-0.8 microg x 100 ml limb volume-1 x min-1) were infused incrementally in the brachial and femoral arteries of 12 normal volunteers; changes in limb blood flow were quantified by using strain-gauge plethysmography.	Isoproterenol	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
11960963-3	2002	Isoproterenol (0.75-24 ng x 100 ml limb volume-1 x min-1) and phenylephrine (0.025-0.8 microg x 100 ml limb volume-1 x min-1) were infused incrementally in the brachial and femoral arteries of 12 normal volunteers; changes in limb blood flow were quantified by using strain-gauge plethysmography.	Isoproterenol	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
11960963-3	2002	Isoproterenol (0.75-24 ng x 100 ml limb volume-1 x min-1) and phenylephrine (0.025-0.8 microg x 100 ml limb volume-1 x min-1) were infused incrementally in the brachial and femoral arteries of 12 normal volunteers; changes in limb blood flow were quantified by using strain-gauge plethysmography.	Phenylephrine	62-75	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
12774323-2	2002	METHOD: HPLC method was used, with Alltech C18 column, acetonitrile-methol-water (43:5:52) as mobile phase with a flow rate of 0.8 mL.min-1, detecting wavelength 280 nm, and column temperature 35 degrees C. RESULT: Retained time of 6-gingerol was near 19 min, showing a good recovery (98.2%) and linear correlation (r = 0.9999).	Water	75-80	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
11956353-5	2002	Glucose was infused intraduodenally at a rate of either 1 or 3 kcal min(-1), for 60 min, (0-60 min) followed by 0.9 % saline for a further 60 min (60-120 min).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
11956353-9	2002	The rises in blood glucose (P < 0.01) and plasma insulin (P < 0.05) concentrations were greater during the 3 kcal min(-1) infusion.	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	120-126
11916780-9	2002	In conclusion, 8 microg x kg(-1) x min(-1) IV almitrine prevents and limits the OLV-induced decrease in PaO2 without causing any hemodynamic modification.	Almitrine	46-55	CD59 molecule (CD59 blood group)	Homo sapiens	35-41
11916780-9	2002	In conclusion, 8 microg x kg(-1) x min(-1) IV almitrine prevents and limits the OLV-induced decrease in PaO2 without causing any hemodynamic modification.	pao2	104-108	CD59 molecule (CD59 blood group)	Homo sapiens	35-41
11916780-10	2002	IMPLICATIONS: Eight microg x kg(-1) x min(-1) IV almitrine limits one-lung ventilation-induced decrease in PaO2 without causing any hemodynamic modification in patients without pulmonary hypertension.	Almitrine	49-58	CD59 molecule (CD59 blood group)	Homo sapiens	38-44
11916780-10	2002	IMPLICATIONS: Eight microg x kg(-1) x min(-1) IV almitrine limits one-lung ventilation-induced decrease in PaO2 without causing any hemodynamic modification in patients without pulmonary hypertension.	pao2	107-111	CD59 molecule (CD59 blood group)	Homo sapiens	38-44
11927475-2	2002	METHODS: Remifentanil was infused for 20 min at a rate of 0.1 microg x kg(-1) x min(-1).	Remifentanil	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	80-86
12095139-6	2002	Splanchnic oxygen consumption increased in cardiac surgery patients from 39 (5) mL x min(-1) x m(-2) to 46 (6) mL x min(-1) x m(-2) (P = 0.003) but decreased in septic patients from 61 (19) mL x min(-1) x m(-2) to 51 (17) L x min(-1) x m(-2) (p = 0.021).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
12042249-2	2002	N-Linked glycans were released with peptide-N-glycosidase F (PNGase F) within gel from SDS-PAGE-isolated soluble and glycosylphosphatidylinositol (GPI)-anchored human CD59 expressed in CHO cells.	n-linked glycans	0-16	CD59 molecule (CD59 blood group)	Homo sapiens	167-171
12042249-2	2002	N-Linked glycans were released with peptide-N-glycosidase F (PNGase F) within gel from SDS-PAGE-isolated soluble and glycosylphosphatidylinositol (GPI)-anchored human CD59 expressed in CHO cells.	Sodium Dodecyl Sulfate	87-90	CD59 molecule (CD59 blood group)	Homo sapiens	167-171
12042249-2	2002	N-Linked glycans were released with peptide-N-glycosidase F (PNGase F) within gel from SDS-PAGE-isolated soluble and glycosylphosphatidylinositol (GPI)-anchored human CD59 expressed in CHO cells.	Glycosylphosphatidylinositols	117-145	CD59 molecule (CD59 blood group)	Homo sapiens	167-171
12042249-2	2002	N-Linked glycans were released with peptide-N-glycosidase F (PNGase F) within gel from SDS-PAGE-isolated soluble and glycosylphosphatidylinositol (GPI)-anchored human CD59 expressed in CHO cells.	Glycosylphosphatidylinositols	147-150	CD59 molecule (CD59 blood group)	Homo sapiens	167-171
12186694-1	2002	CD55 and CD59 are complement regulatory proteins that are linked to the cell membrane via a glycosyl-phosphatidylinositol anchor.	Glycosylphosphatidylinositols	92-121	CD59 molecule (CD59 blood group)	Homo sapiens	9-13
11899188-10	2002	The cardiac index averaged 2.7+/-0.8 L x min(-1) x m(-2) in control patients and 2.9+/-0.7 L x min(-1) x m(-2) in arginine patients immediately after surgery (p = 0.09).	Arginine	114-122	CD59 molecule (CD59 blood group)	Homo sapiens	95-101
12455733-7	2002	A rate constant per unit O2 concentration of 9.40E-10 ppm(-2) min(-1) for humidified gas was significantly higher than 8.27E-10 ppm(-2) min(-1) for "dry" gas (P = 0.008) at 22 degrees C. Rise in NO2 predicted from the "wet" rate constant achieved 3ppm in 65 seconds with 40 ppm NO in 100% oxygen and 107 sec.	Oxygen	25-27	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
12455733-7	2002	A rate constant per unit O2 concentration of 9.40E-10 ppm(-2) min(-1) for humidified gas was significantly higher than 8.27E-10 ppm(-2) min(-1) for "dry" gas (P = 0.008) at 22 degrees C. Rise in NO2 predicted from the "wet" rate constant achieved 3ppm in 65 seconds with 40 ppm NO in 100% oxygen and 107 sec.	Oxygen	25-27	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
12455733-7	2002	A rate constant per unit O2 concentration of 9.40E-10 ppm(-2) min(-1) for humidified gas was significantly higher than 8.27E-10 ppm(-2) min(-1) for "dry" gas (P = 0.008) at 22 degrees C. Rise in NO2 predicted from the "wet" rate constant achieved 3ppm in 65 seconds with 40 ppm NO in 100% oxygen and 107 sec.	Nitrogen Dioxide	195-198	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
12455733-7	2002	A rate constant per unit O2 concentration of 9.40E-10 ppm(-2) min(-1) for humidified gas was significantly higher than 8.27E-10 ppm(-2) min(-1) for "dry" gas (P = 0.008) at 22 degrees C. Rise in NO2 predicted from the "wet" rate constant achieved 3ppm in 65 seconds with 40 ppm NO in 100% oxygen and 107 sec.	Oxygen	289-295	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
11932581-4	2002	During the descent, oxygen uptake and heart rate during the last 30 s of the climb were 17.0 +/- 3.8 mL.kg(-1).min(-1) and 107 +/- 18 beats.min(-1), respectively.	Oxygen	20-26	CD59 molecule (CD59 blood group)	Homo sapiens	140-146
11907418-8	2002	During cyclosporine, glomerular filtration rate decreased from 98+/-9 ml/min/1.732 to 85+/-10 ml/min/1.732 (P<0.05), and ERPF decreased from 597+/-108 ml/min/1.732 to 438+/-84 ml/min/1.732 (P<0.01).	Cyclosporine	7-19	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
11907418-8	2002	During cyclosporine, glomerular filtration rate decreased from 98+/-9 ml/min/1.732 to 85+/-10 ml/min/1.732 (P<0.05), and ERPF decreased from 597+/-108 ml/min/1.732 to 438+/-84 ml/min/1.732 (P<0.01).	Cyclosporine	7-19	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
11907418-8	2002	During cyclosporine, glomerular filtration rate decreased from 98+/-9 ml/min/1.732 to 85+/-10 ml/min/1.732 (P<0.05), and ERPF decreased from 597+/-108 ml/min/1.732 to 438+/-84 ml/min/1.732 (P<0.01).	Cyclosporine	7-19	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
11907418-8	2002	During cyclosporine, glomerular filtration rate decreased from 98+/-9 ml/min/1.732 to 85+/-10 ml/min/1.732 (P<0.05), and ERPF decreased from 597+/-108 ml/min/1.732 to 438+/-84 ml/min/1.732 (P<0.01).	Cyclosporine	7-19	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
12069204-1	2002	PROBLEM: Prostasomes isolated from human seminal plasma have complement regulatory properties because of their content of CD59, a glycosylphosphatidylinositol (GPI)-anchored protein.	Glycosylphosphatidylinositols	130-158	CD59 molecule (CD59 blood group)	Homo sapiens	122-126
12069204-1	2002	PROBLEM: Prostasomes isolated from human seminal plasma have complement regulatory properties because of their content of CD59, a glycosylphosphatidylinositol (GPI)-anchored protein.	Glycosylphosphatidylinositols	160-163	CD59 molecule (CD59 blood group)	Homo sapiens	122-126
11969156-6	2002	The rate constant for one stage of the conversion of luminol oxidation product is approximately 0.2 min-1, and the rate constant of the other is severalfold greater.	Luminol	53-60	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
11880482-5	2002	Mathematical modeling of the three established pathways for neurotransmitter glutamate repletion indicates that the glutamate/glutamine neurotransmitter cycle between astroglia and neurons (0.32 +/- 0.07 micromol x gm(-1) x min(-1)) is the major pathway for neuronal glutamate repletion and that the astroglial TCA cycle flux (0.14 +/- 0.06 micromol x gm(-1) x min(-1)) accounts for approximately 14% of brain oxygen consumption.	Glutamic Acid	116-125	CD59 molecule (CD59 blood group)	Homo sapiens	224-230
11861350-7	2002	RESULTS: The measured inspired O(2) concentration was higher in the OA at 2 (26.3 +/- 2.5 vs 23.3 +/- 0.5, P <0.01) and 6 L x min(-1) (33.5 +/- 3.3 vs 28.8 +/- 1.2, P <0.01) flow rates.	Oxygen	31-35	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
11884493-9	2002	Using the compartmental model method, k(4) for (18)F-fluoride was shown to lie in the range 0--0.0025 min(-1) with a best-fit value of 0.0018 min(-1).	Fluorine	51-53	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
11884493-9	2002	Using the compartmental model method, k(4) for (18)F-fluoride was shown to lie in the range 0--0.0025 min(-1) with a best-fit value of 0.0018 min(-1).	Fluorine	51-53	CD59 molecule (CD59 blood group)	Homo sapiens	142-148
11884493-9	2002	Using the compartmental model method, k(4) for (18)F-fluoride was shown to lie in the range 0--0.0025 min(-1) with a best-fit value of 0.0018 min(-1).	Fluorides	53-61	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
11884493-9	2002	Using the compartmental model method, k(4) for (18)F-fluoride was shown to lie in the range 0--0.0025 min(-1) with a best-fit value of 0.0018 min(-1).	Fluorides	53-61	CD59 molecule (CD59 blood group)	Homo sapiens	142-148
11880482-5	2002	Mathematical modeling of the three established pathways for neurotransmitter glutamate repletion indicates that the glutamate/glutamine neurotransmitter cycle between astroglia and neurons (0.32 +/- 0.07 micromol x gm(-1) x min(-1)) is the major pathway for neuronal glutamate repletion and that the astroglial TCA cycle flux (0.14 +/- 0.06 micromol x gm(-1) x min(-1)) accounts for approximately 14% of brain oxygen consumption.	Glutamic Acid	116-125	CD59 molecule (CD59 blood group)	Homo sapiens	361-367
11880482-5	2002	Mathematical modeling of the three established pathways for neurotransmitter glutamate repletion indicates that the glutamate/glutamine neurotransmitter cycle between astroglia and neurons (0.32 +/- 0.07 micromol x gm(-1) x min(-1)) is the major pathway for neuronal glutamate repletion and that the astroglial TCA cycle flux (0.14 +/- 0.06 micromol x gm(-1) x min(-1)) accounts for approximately 14% of brain oxygen consumption.	Glutamine	126-135	CD59 molecule (CD59 blood group)	Homo sapiens	224-230
11880482-5	2002	Mathematical modeling of the three established pathways for neurotransmitter glutamate repletion indicates that the glutamate/glutamine neurotransmitter cycle between astroglia and neurons (0.32 +/- 0.07 micromol x gm(-1) x min(-1)) is the major pathway for neuronal glutamate repletion and that the astroglial TCA cycle flux (0.14 +/- 0.06 micromol x gm(-1) x min(-1)) accounts for approximately 14% of brain oxygen consumption.	Glutamine	126-135	CD59 molecule (CD59 blood group)	Homo sapiens	361-367
11880482-5	2002	Mathematical modeling of the three established pathways for neurotransmitter glutamate repletion indicates that the glutamate/glutamine neurotransmitter cycle between astroglia and neurons (0.32 +/- 0.07 micromol x gm(-1) x min(-1)) is the major pathway for neuronal glutamate repletion and that the astroglial TCA cycle flux (0.14 +/- 0.06 micromol x gm(-1) x min(-1)) accounts for approximately 14% of brain oxygen consumption.	Glutamic Acid	116-125	CD59 molecule (CD59 blood group)	Homo sapiens	224-230
11880482-5	2002	Mathematical modeling of the three established pathways for neurotransmitter glutamate repletion indicates that the glutamate/glutamine neurotransmitter cycle between astroglia and neurons (0.32 +/- 0.07 micromol x gm(-1) x min(-1)) is the major pathway for neuronal glutamate repletion and that the astroglial TCA cycle flux (0.14 +/- 0.06 micromol x gm(-1) x min(-1)) accounts for approximately 14% of brain oxygen consumption.	Glutamic Acid	116-125	CD59 molecule (CD59 blood group)	Homo sapiens	361-367
14647800-9	2002	She was undernourished and the laboratory examinations showed urea (69 mg/dl), creatinine (2.2 mg/dl) and creatinine clearance (12.5 ml/min/1.73 m2 SA).	2-chloro-10-(4'(N-beta-hydroxyethyl)piperazinyl-1')acetylphenothiazine	148-150	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
11878380-7	2002	Using the method of initial rates, the aqueous-phase reactions were found to have first-order dependencies on Fe(II), NH2Cl, and OH- and a rate coefficient (kNH2Cl,soln) of 3.10 (+/-0.560) x 10(9) M(-2) min(-1).	ammonium ferrous sulfate	110-116	CD59 molecule (CD59 blood group)	Homo sapiens	203-209
11878380-7	2002	Using the method of initial rates, the aqueous-phase reactions were found to have first-order dependencies on Fe(II), NH2Cl, and OH- and a rate coefficient (kNH2Cl,soln) of 3.10 (+/-0.560) x 10(9) M(-2) min(-1).	chloramine	118-123	CD59 molecule (CD59 blood group)	Homo sapiens	203-209
11878380-7	2002	Using the method of initial rates, the aqueous-phase reactions were found to have first-order dependencies on Fe(II), NH2Cl, and OH- and a rate coefficient (kNH2Cl,soln) of 3.10 (+/-0.560) x 10(9) M(-2) min(-1).	knh2cl	157-163	CD59 molecule (CD59 blood group)	Homo sapiens	203-209
11851636-9	2002	Erythromycin caused a statistically significant reduction in midazolam clearance from the original value of 3.8 to 2.5 (95% CI for the difference -2.27, -0.35) ml kg-1 min-1.	Erythromycin	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
11851646-6	2002	While the administration of nilvadipine alone elicited a significant (P < 0.05) hypotensive (mean difference for diastolic blood pressure -8 mmHg, 95% CI -4, -12 mmHg) and reflex tachycardia (mean difference 5 beats min-1, 95% CI 1, 9 beats min-1), the treatment with rifampicin abolished these responses.	nilvadipine	28-39	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
11851646-6	2002	While the administration of nilvadipine alone elicited a significant (P < 0.05) hypotensive (mean difference for diastolic blood pressure -8 mmHg, 95% CI -4, -12 mmHg) and reflex tachycardia (mean difference 5 beats min-1, 95% CI 1, 9 beats min-1), the treatment with rifampicin abolished these responses.	nilvadipine	28-39	CD59 molecule (CD59 blood group)	Homo sapiens	244-249
11893158-3	2002	Results from ion exchange at a flowrate of 20 ml min(-1) showed breakthrough effluent concentrations obtained at 0.59 mg l(-1) chromium, 3.92 microg l(-1) mercury and 0.65 mg l(-1) silver corresponding to 75.6 l at 63 hr, 40.8 l at 34 hr and 33.6 l at 28 hr respectively.	Chromium	127-135	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
11893158-3	2002	Results from ion exchange at a flowrate of 20 ml min(-1) showed breakthrough effluent concentrations obtained at 0.59 mg l(-1) chromium, 3.92 microg l(-1) mercury and 0.65 mg l(-1) silver corresponding to 75.6 l at 63 hr, 40.8 l at 34 hr and 33.6 l at 28 hr respectively.	Mercury	155-162	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
11893158-3	2002	Results from ion exchange at a flowrate of 20 ml min(-1) showed breakthrough effluent concentrations obtained at 0.59 mg l(-1) chromium, 3.92 microg l(-1) mercury and 0.65 mg l(-1) silver corresponding to 75.6 l at 63 hr, 40.8 l at 34 hr and 33.6 l at 28 hr respectively.	Silver	181-187	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
11936706-11	2002	The mean clearance of R-ketamine, 0.020 l min(-1) kg(-1), was slightly but significantly lower than of S-ketamine, 0.024 l min(-1) kg(-1).	r-ketamine	22-32	CD59 molecule (CD59 blood group)	Homo sapiens	42-48
11807824-1	2002	Protectin (CD59) is a glycosylphosphatidylinositol (GPI)-anchored cell membrane glycoprotein, broadly expressed on melanocytic cells, that represents the main restriction factor of complement (C)-mediated lysis of human melanoma cells.	Glycosylphosphatidylinositols	22-50	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
11807824-1	2002	Protectin (CD59) is a glycosylphosphatidylinositol (GPI)-anchored cell membrane glycoprotein, broadly expressed on melanocytic cells, that represents the main restriction factor of complement (C)-mediated lysis of human melanoma cells.	Glycosylphosphatidylinositols	52-55	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
11834047-2	2002	With a loading dose of 50 microg/kg followed by an infusion of 0.5 microg x kg(-1) x min(-1), milrinone increases stroke volume index and left ventricular velocity of circumferential fiber shortening after weaning from cardiopulmonary bypass.	Milrinone	94-103	CD59 molecule (CD59 blood group)	Homo sapiens	85-91
11756148-9	2002	Unlike PNH cells, 6-TG-resistant cells expressed CD59, indicating that the HPRT mutations did not occur in PNH clones.	Thioguanine	18-22	CD59 molecule (CD59 blood group)	Homo sapiens	49-53
11806533-3	2002	The sonochemical decomposition rate constant for bromobenzene (k = 0.044 +/- 7.50 x 10(-4) min(-1) at 20 kHz) was not significantly impacted by very fine silica particles (10 nm).	bromobenzene	49-61	CD59 molecule (CD59 blood group)	Homo sapiens	91-97
11913801-5	2002	According to random allocation, patients received either fenoldopam (0.1 microg kg(-1) min(-1)) or placebo intravenously prior to surgical skin incision until release of the aortic clamp.	Fenoldopam	57-67	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
11774067-6	2002	Percent body fat was negatively associated with ET and relative oxygen uptake (ml x min(-1) x kg(-1)) and was positively related to submaximal heart rate at 6 minutes exercise (HR6).	Oxygen	64-70	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
11774067-7	2002	Fat-free mass was positively related to W(total), P(max) and absolute oxygen uptake (ml x min(-1)).	Oxygen	70-76	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
11774067-8	2002	Relative oxygen uptake (ml x min(-1) x kg(-1)) was related to ET.	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	29-35
11774067-9	2002	Absolute oxygen uptake (ml x min(-1)) was related to W(total) and P(max).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	29-35
14517639-5	2002	The repeated vital capacity breathing technique was used, with 5% sevoflurane in 10 l.min(-1) oxygen.	Oxygen	94-100	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
11788655-2	2002	Insulin-stimulated glucose uptake was decreased both in the diabetic and nondiabetic twin, compared with healthy control subjects (5.2 +/- 0.7 and 8.5 +/- 0.8 vs. 11.4 +/- 0.9 mg/kg x min(-1); P < 0.01 and P < 0.02, respectively).	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	184-190
12793919-9	2002	INTERVENTIONS: Dopamine was administered in doses of 5, 10, 0, and 5 microg x kg(-1) x min(-1), 20 mins on each level.	Dopamine	15-23	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
12511181-19	2002	It may thus be concluded that: a) generation of the same external mechanical power output during cycling at a pedalling rate of 120 rev.min(-1) causes significantly higher [K+]v changes than when cycling at 60 rev.min(-1), b) the increase of venous plasma potassium concentration during dynamic incremental exercise is linearly related to the metabolic cost of work expressed by the percentage of VO2max (increase as reported previously by Vollestad et al.	Potassium	256-265	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
12510782-5	2002	RESULTS: Oxygen flow peaked at 5.74 +/- 0.28 L x min(-1) (mean +/- SD) at 16.9 +/- 1.5 minutes before rapidly falling to zero.	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
11913801-7	2002	RESULTS: Fenoldopam (0.1 microg kg(-1)min(-1)) administration was not associated with haemodynamic instability.	Fenoldopam	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	38-44
11754418-0	2001	Monitoring of CD59 expression in paroxysmal nocturnal hemoglobinuria treated with danazol.	Danazol	82-89	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
11701450-5	2001	Basal glycerol rate of appearance (R(a)) in plasma, an indicator of whole body lipolytic rate, was greater in women than in men (2.1 +/- 0.2 vs. 1.5 +/- 0.1 micromol x kg body wt(-1) x min(-1); P < 0.05).	Glycerol	6-14	CD59 molecule (CD59 blood group)	Homo sapiens	185-191
11736880-6	2001	Verapamil attenuated the increases in systolic blood pressure (25 +/- 2 vs 30 +/- 2 mmHg, difference 4.6, 95% CI (1.0, 8.1), P < 0.01) and rate-pressure product (3.1 +/- 0.2 vs 3.6 +/- 0.3 x 10(3) mmHg x beats min(-1), difference 0.5, 95% CI (0.1, 0.9), P < 0.01) during handgrip compared with amlodipine.	Verapamil	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	213-219
11736772-2	2001	Thirty-one patients received an infusion of esmolol 0-300 microg x kg(-1) x min(-1) and 37 patients comprised the control group.	esmolol	44-51	CD59 molecule (CD59 blood group)	Homo sapiens	76-82
11829095-9	2001	Respirologists in Canada and the USA increased the resting Sa,O2 by 1-2 L x min(-1) during sleep, while those in Spain used the resting (awake) flow for the night prescription (62%).	Oxygen	62-64	CD59 molecule (CD59 blood group)	Homo sapiens	76-82
11785641-8	2001	The limits of quantification (10sigma of the blank hydrazones) of formaldehyde and acetaldehyde were 2.2 and 1.2 ppb, respectively, for 21.9 L (0.15 L min(-1) for 146 min) of air sample volume.	Formaldehyde	66-78	CD59 molecule (CD59 blood group)	Homo sapiens	151-157
15100869-10	2001	100 microM fluorescein at 6 microL min(-1) was used as sample flow and water at increasing flow rates as sheath flow.	Fluorescein	11-22	CD59 molecule (CD59 blood group)	Homo sapiens	35-41
11700403-9	2001	Indexes of respiratory effort decreased significantly during the two modes of NIMV compared with spontaneous breathing, with PTPdi/min decreasing from 497.8 +/- 115.4 cm H2O x sec x min(-1) during spontaneous breathing to 127.8 +/- 98.3 cm H2O x sec x min(-1) and 184.3 +/- 79.8 cm H2O x sec x min(-1), during AC/VT and pressure support, respectively (p <.0001), and the work of breathing decreasing from 1.83 +/- 0.12 J.L-1 during spontaneous breathing to 0.48 +/- 0.32 J.L-1 and 0.75 +/- 0.30 J.L-1, during AC/VT and pressure support, respectively (p <.0001).	nimv	78-82	CD59 molecule (CD59 blood group)	Homo sapiens	182-188
11719729-7	2001	S(+)-ketamine showed a significantly higher clearance (26.3 +/- 3.5 ml x kg(-1) x min(-1)) compared with racemic ketamine (14.8 +/- 1.7 ml x kg(-1) x min(-1); P <.05) and R(-)-ketamine (13.8 +/- 1.3 ml x kg(-1) x min(-1); P <.05).	Ketamine	1-13	CD59 molecule (CD59 blood group)	Homo sapiens	82-88
11719729-7	2001	S(+)-ketamine showed a significantly higher clearance (26.3 +/- 3.5 ml x kg(-1) x min(-1)) compared with racemic ketamine (14.8 +/- 1.7 ml x kg(-1) x min(-1); P <.05) and R(-)-ketamine (13.8 +/- 1.3 ml x kg(-1) x min(-1); P <.05).	Ketamine	1-13	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
11719729-7	2001	S(+)-ketamine showed a significantly higher clearance (26.3 +/- 3.5 ml x kg(-1) x min(-1)) compared with racemic ketamine (14.8 +/- 1.7 ml x kg(-1) x min(-1); P <.05) and R(-)-ketamine (13.8 +/- 1.3 ml x kg(-1) x min(-1); P <.05).	Ketamine	1-13	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
11719729-7	2001	S(+)-ketamine showed a significantly higher clearance (26.3 +/- 3.5 ml x kg(-1) x min(-1)) compared with racemic ketamine (14.8 +/- 1.7 ml x kg(-1) x min(-1); P <.05) and R(-)-ketamine (13.8 +/- 1.3 ml x kg(-1) x min(-1); P <.05).	Ketamine	5-13	CD59 molecule (CD59 blood group)	Homo sapiens	82-88
11700403-9	2001	Indexes of respiratory effort decreased significantly during the two modes of NIMV compared with spontaneous breathing, with PTPdi/min decreasing from 497.8 +/- 115.4 cm H2O x sec x min(-1) during spontaneous breathing to 127.8 +/- 98.3 cm H2O x sec x min(-1) and 184.3 +/- 79.8 cm H2O x sec x min(-1), during AC/VT and pressure support, respectively (p <.0001), and the work of breathing decreasing from 1.83 +/- 0.12 J.L-1 during spontaneous breathing to 0.48 +/- 0.32 J.L-1 and 0.75 +/- 0.30 J.L-1, during AC/VT and pressure support, respectively (p <.0001).	nimv	78-82	CD59 molecule (CD59 blood group)	Homo sapiens	252-258
11719729-7	2001	S(+)-ketamine showed a significantly higher clearance (26.3 +/- 3.5 ml x kg(-1) x min(-1)) compared with racemic ketamine (14.8 +/- 1.7 ml x kg(-1) x min(-1); P <.05) and R(-)-ketamine (13.8 +/- 1.3 ml x kg(-1) x min(-1); P <.05).	Ketamine	5-13	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
11719729-7	2001	S(+)-ketamine showed a significantly higher clearance (26.3 +/- 3.5 ml x kg(-1) x min(-1)) compared with racemic ketamine (14.8 +/- 1.7 ml x kg(-1) x min(-1); P <.05) and R(-)-ketamine (13.8 +/- 1.3 ml x kg(-1) x min(-1); P <.05).	Ketamine	5-13	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
11719729-8	2001	Furthermore, the clearance of the S (+)-ketamine was smaller in the racemate (18.5 +/- 0.7 ml x kg(-1) x min(-1); P <.05) than for the pure isomer.	Sulfur	34-35	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
11719729-8	2001	Furthermore, the clearance of the S (+)-ketamine was smaller in the racemate (18.5 +/- 0.7 ml x kg(-1) x min(-1); P <.05) than for the pure isomer.	Ketamine	36-48	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
11700403-9	2001	Indexes of respiratory effort decreased significantly during the two modes of NIMV compared with spontaneous breathing, with PTPdi/min decreasing from 497.8 +/- 115.4 cm H2O x sec x min(-1) during spontaneous breathing to 127.8 +/- 98.3 cm H2O x sec x min(-1) and 184.3 +/- 79.8 cm H2O x sec x min(-1), during AC/VT and pressure support, respectively (p <.0001), and the work of breathing decreasing from 1.83 +/- 0.12 J.L-1 during spontaneous breathing to 0.48 +/- 0.32 J.L-1 and 0.75 +/- 0.30 J.L-1, during AC/VT and pressure support, respectively (p <.0001).	nimv	78-82	CD59 molecule (CD59 blood group)	Homo sapiens	252-258
11689745-5	2001	RESULTS: In the training group: a) maximal oxygen uptake (VO2max) increased from 58.1 +/- 4.5 mL x kg(-1) x min(-1) to 64.3 +/- 3.9 mL x kg(-1) x min(-1) (P < 0.01); b) lactate threshold improved from 47.8 +/- 5.3 mL x kg(-1) x min(-1) to 55.4 +/- 4.1 mL x kg(-1) x min(-1) (P < 0.01); c) running economy was also improved by 6.7% (P < 0.05); d) distance covered during a match increased by 20% in the training group (P < 0.01); e) number of sprints increased by 100% (P < 0.01); f) number of involvements with the ball increased by 24% (P < 0.05); g) the average work intensity during a soccer match, measured as percent of maximal heart rate, was enhanced from 82.7 +/- 3.4% to 85.6 +/- 3.1% (P < 0.05); and h) no changes were found in maximal vertical jumping height, strength, speed, kicking velocity, kicking precision, or quality of passes after the training period.	Oxygen	43-49	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
11679448-2	2001	Therefore, we tested the hypothesis that short-term (4 weeks) moderate energy restriction (-750 kcal/day) would result in a significant increase in insulin-stimulated glucose disposal (40 mU x m(-2) x min(-1) hyperinsulinemic-euglycemic clamp) in moderately overweight postmenopausal women and that when combined with resistance training (RT) an even greater effect would be seen.	Glucose	167-174	CD59 molecule (CD59 blood group)	Homo sapiens	201-207
11758331-5	2001	After induction of anesthesia with propofol 50 mg, and fentanyl 100 micrograms, heart rate decreased to 36 min-1 and remained low after tracheal intubation.	Propofol	35-43	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
11758331-5	2001	After induction of anesthesia with propofol 50 mg, and fentanyl 100 micrograms, heart rate decreased to 36 min-1 and remained low after tracheal intubation.	Fentanyl	55-63	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
11758334-4	2001	Anesthesia was induced with sevoflurane slowly increased to 5% in nitrous oxide 3 l.min-1 with oxygen 3 l.min-1.	Sevoflurane	28-39	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
11758334-4	2001	Anesthesia was induced with sevoflurane slowly increased to 5% in nitrous oxide 3 l.min-1 with oxygen 3 l.min-1.	Nitrous Oxide	66-79	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
11758334-4	2001	Anesthesia was induced with sevoflurane slowly increased to 5% in nitrous oxide 3 l.min-1 with oxygen 3 l.min-1.	Oxygen	95-101	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
11758334-4	2001	Anesthesia was induced with sevoflurane slowly increased to 5% in nitrous oxide 3 l.min-1 with oxygen 3 l.min-1.	Oxygen	95-101	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
11765143-14	2001	For both formulations, the renal clearance of sitafloxacin (means of 181 and 198 ml min(-1) for the capsule and i.v.	sitafloxacin	46-58	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
11576097-4	2001	Patients were randomly assigned to receive continuous infusions of fenoldopam 0.1 microg x kg(-1) x min(-1) (n = 16) or placebo (n = 15).	Fenoldopam	67-77	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
11602866-5	2001	RESULTS: Sildenafil increased glomerular filtration rate by 14+/-4 from the baseline value of 55+/-7 ml x min(-1) x 1.73 m2(-1) (P<0.01), whereas calculated renal vascular resistances decreased by 40+/-18 from the baseline value of 247+/-29 mmHg/L x min(-1) x 1.73 m2-1 (P<0.05).	Sildenafil Citrate	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	106-112
11602866-5	2001	RESULTS: Sildenafil increased glomerular filtration rate by 14+/-4 from the baseline value of 55+/-7 ml x min(-1) x 1.73 m2(-1) (P<0.01), whereas calculated renal vascular resistances decreased by 40+/-18 from the baseline value of 247+/-29 mmHg/L x min(-1) x 1.73 m2-1 (P<0.05).	Sildenafil Citrate	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	253-259
11605929-7	2001	RESULTS: Plasma propofol concentrations were approximately 0.5 microg/ml for P(low) and approximately 1.3 mg/ml for P(high), Propofol reduced the central carbon dioxide sensitivity from 1.5 +/- 0.4 to 1.2 +/- 0.3 (P(low); P < 0.01 vs. control) and 0.9 +/- 0.1 l x min(-1) x mmHg(-1) (P(high); P < 0.001 vs. control).	Propofol	125-133	CD59 molecule (CD59 blood group)	Homo sapiens	267-273
11605929-7	2001	RESULTS: Plasma propofol concentrations were approximately 0.5 microg/ml for P(low) and approximately 1.3 mg/ml for P(high), Propofol reduced the central carbon dioxide sensitivity from 1.5 +/- 0.4 to 1.2 +/- 0.3 (P(low); P < 0.01 vs. control) and 0.9 +/- 0.1 l x min(-1) x mmHg(-1) (P(high); P < 0.001 vs. control).	Carbon Dioxide	154-168	CD59 molecule (CD59 blood group)	Homo sapiens	267-273
11566025-2	2001	Uptake of MTX vs concentration was saturable at pH 7.4 in cells grown in normal medium and in cells incubated for 24 h in folate-free medium (Km = 3.24 and 4.84 microM, respectively (P > 0.05, n = 3) and Vmax = 0.64 and 0.92 nmol x min(-1) x 10(-9) cells, respectively (P < 0.05, n = 3)).	Methotrexate	10-13	CD59 molecule (CD59 blood group)	Homo sapiens	235-241
11695293-10	2001	The creatinine clearance estimated by the Cockcroft formula was 50 mL.min-1.	Creatinine	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
11695293-13	2001	Three months after the transplantation, creatinine clearance was 80 mL.min-1.	Creatinine	40-50	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
11576357-8	2001	RESULTS: Candesartan induced a mean (SE) reduction in mean arterial blood pressure (MABP) of 6 (2) mm Hg (P < 0.02) and had a tendency to reduce UAER (P = 0.07), while GFR remained unchanged (95 vs. 93 mL/min/1.73 m2).	candesartan	9-20	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
11685376-1	2001	Washed cells of Desulfovibrio vulgaris strain Marburg (DSM 2119) reduced oxygen to water with H(2) as electron donor at a mean rate of 253 nmol O(2) min(-1) (mg protein)(-1).	Oxygen	73-79	CD59 molecule (CD59 blood group)	Homo sapiens	149-155
11685376-1	2001	Washed cells of Desulfovibrio vulgaris strain Marburg (DSM 2119) reduced oxygen to water with H(2) as electron donor at a mean rate of 253 nmol O(2) min(-1) (mg protein)(-1).	h(2)	94-98	CD59 molecule (CD59 blood group)	Homo sapiens	149-155
11579174-13	2001	Muscle V(O2) increased (P < 0.05) by 0.06 +/- 0.03 (12 %) and 0.09 +/- 0.03 l min(-1) (14 %) from the third minute to the end of exercise at 60 and 100 r.p.m., respectively, but there was no difference between the two frequencies.	Oxygen	9-11	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
11680000-7	2001	In the follow-up group, creatinine clearance decreased from 27.5 +/- 9.5 mL/min initially, to 19.4 +/- 6.25 mL/min at 3 months, to 13.0 +/- 3.8 mL/min at 6 months (P <.001), while RMR/BW and RMR/BSA increased from 98.28 +/- 6.3, to 101.64 +/- 5.46, to 105.42 +/- 6.3 kJ/kg BW/d (P <.005), respectively, and 4.41 +/- 0.126, to 4.578 +/- 0.168, to 4.704 +/- 0.168 kJ/min/1.73 m(2) (P <.05), respectively.	Creatinine	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	371-376
11576357-10	2001	GFR diminished in average from 95 (3) to 92 (4) mL/min/1.73 m2 with placebo (NS), and from 93 (3) to 89 (4) mL/min/1.73 m2 during treatment with candesartan (NS).	candesartan	145-156	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
11576357-11	2001	The mean difference (95% CI) in the changes in GFR between the examination with placebo and with candesartan was 0.1 (-5.5 to 5.8) mL/min/1.73 m2 (NS).	candesartan	97-108	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
11744946-8	2001	Absolute maximal oxygen uptake increased linearly from 1.2 +/- 0.2 L x min(-1) at age 7-9 years to 2.5 +/- 0.5 L x min(-1) at age 13-15 years.	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	71-77
11744946-8	2001	Absolute maximal oxygen uptake increased linearly from 1.2 +/- 0.2 L x min(-1) at age 7-9 years to 2.5 +/- 0.5 L x min(-1) at age 13-15 years.	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
11822291-6	2001	The flow rate of Nitrogen was 27 ml.min-1.	Nitrogen	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
11522675-7	2001	Renal glucose balance switched from a mean +/- SE baseline net uptake of 0.6 +/- 0.4 to a net output of 4.5 +/- 1.3 micromol x kg(-1) x min(-1) in normal subjects, but in patients with diabetes there was no net renal contribution to blood glucose during similar hypoglycemia (mean +/- SE net glucose uptake [baseline 0.7 +/- 0.4] remained at 0.4 +/- 0.3 micromol x kg(-1) x min(-1) in the final 40 min of hypoglycemia; P < 0.01 between groups).	Glucose	6-13	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
11522675-7	2001	Renal glucose balance switched from a mean +/- SE baseline net uptake of 0.6 +/- 0.4 to a net output of 4.5 +/- 1.3 micromol x kg(-1) x min(-1) in normal subjects, but in patients with diabetes there was no net renal contribution to blood glucose during similar hypoglycemia (mean +/- SE net glucose uptake [baseline 0.7 +/- 0.4] remained at 0.4 +/- 0.3 micromol x kg(-1) x min(-1) in the final 40 min of hypoglycemia; P < 0.01 between groups).	Glucose	6-13	CD59 molecule (CD59 blood group)	Homo sapiens	374-380
11553256-9	2001	In remifentanil-treated patients, continuation of the infusion at 0.1 microg kg(-1) min(-1) with titration increments of +/- 0.025 microg kg(-1) min(-1) was effective for the management of immediate postoperative pain prior to transfer to morphine analgesia.	Morphine	239-247	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
11553256-12	2001	Significantly fewer patients responded to tracheal intubation with remifentanil at 0.4 microg kg(-1) min(-1), supporting the use of a higher initial infusion rate before intubation.	Remifentanil	67-79	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
11562620-7	2001	The median creatinine clearance rose from 67.4 to 96.5 mL/min/1.73 m(2) (P <.05) but remained subnormal in 4 patients.	Creatinine	11-21	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
12580108-3	2001	Chromatography column was a Rp-18; the mobile phase was methanol-water (90:10); the flow rate was 1.0 mL.min-1 and the detecting wavelength was 220 nm.	Methanol	56-64	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
12580109-3	2001	The mobile phase consisted of acetonitrile-water-formic acid (20:80:1), at a flow-rate of 0.4 mL.min-1.	Water	43-48	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
11435221-9	2001	We confirmed that cats have a large secretory response to phenylephrine (11.6 +/- 3.7 nl x min(-1) x gland(-1), 12 glands), but pigs, sheep, and humans all have small responses (<2 nl x min(-1)m x gland(-1)).	Phenylephrine	58-71	CD59 molecule (CD59 blood group)	Homo sapiens	91-97
11473555-6	2001	RESULTS: The inspired and end-tidal concentrations of desflurane in the 1.0 L min-1 group after 120 min were 4.54% vs. 4.37% (P < 0.001).	Desflurane	54-64	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
11473555-7	2001	In the 2.0 L min-1 group, the inspired and end-tidal concentrations of desflurane were 4.76% vs. 4.58% (P < 0.001).	Desflurane	71-81	CD59 molecule (CD59 blood group)	Homo sapiens	13-18
11473555-11	2001	CONCLUSION: There is a significant difference between the inspired and end-tidal concentrations of desflurane when fresh gas inflows were 1.0 and 2.0 L min-1, but not for the ratio of inspired/end-tidal.	Desflurane	99-109	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
11511427-12	2001	RESULTS: Breath isoprene production in subjects with CHF was significantly reduced compared to controls 83(23) vs. 168(20) pmol min(-1) kg(-1).	isoprene	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
11569862-9	2001	With addition of 2 mL min(-1) trifluoromethane to the argon flow of 400 mL min(-1) through the tube, transport efficiencies from 20% to 70% and from 70% to 100% were achieved with the standard and nozzle-type tubes, respectively.	fluoroform	30-46	CD59 molecule (CD59 blood group)	Homo sapiens	22-28
11569862-9	2001	With addition of 2 mL min(-1) trifluoromethane to the argon flow of 400 mL min(-1) through the tube, transport efficiencies from 20% to 70% and from 70% to 100% were achieved with the standard and nozzle-type tubes, respectively.	fluoroform	30-46	CD59 molecule (CD59 blood group)	Homo sapiens	75-81
11569862-9	2001	With addition of 2 mL min(-1) trifluoromethane to the argon flow of 400 mL min(-1) through the tube, transport efficiencies from 20% to 70% and from 70% to 100% were achieved with the standard and nozzle-type tubes, respectively.	Argon	54-59	CD59 molecule (CD59 blood group)	Homo sapiens	22-28
11569862-9	2001	With addition of 2 mL min(-1) trifluoromethane to the argon flow of 400 mL min(-1) through the tube, transport efficiencies from 20% to 70% and from 70% to 100% were achieved with the standard and nozzle-type tubes, respectively.	Argon	54-59	CD59 molecule (CD59 blood group)	Homo sapiens	75-81
11604107-0	2001	A monoclonal antibody, MIN/3/60, that recognizes the sulpho-Lewis(x) and sulpho-Lewis(a) sequences detects a sub-population of epithelial glycans in the crypts of human colonic epithelium.	Polysaccharides	138-145	CD59 molecule (CD59 blood group)	Homo sapiens	23-31
11604107-4	2001	We now describe a MAb (rat hybridoma MIN/3/60) raised to 3"-sulpho-Le(x), a carbohydrate sequence which, in vitro, is bound not only by the E-, L-, and P-selectins, but also by the cysteine-rich domain of the macrophage endocytosis receptor.	Carbohydrates	76-88	CD59 molecule (CD59 blood group)	Homo sapiens	37-45
11604107-4	2001	We now describe a MAb (rat hybridoma MIN/3/60) raised to 3"-sulpho-Le(x), a carbohydrate sequence which, in vitro, is bound not only by the E-, L-, and P-selectins, but also by the cysteine-rich domain of the macrophage endocytosis receptor.	e-, l-, and p-selectins	140-163	CD59 molecule (CD59 blood group)	Homo sapiens	37-45
11604107-4	2001	We now describe a MAb (rat hybridoma MIN/3/60) raised to 3"-sulpho-Le(x), a carbohydrate sequence which, in vitro, is bound not only by the E-, L-, and P-selectins, but also by the cysteine-rich domain of the macrophage endocytosis receptor.	Cysteine	181-189	CD59 molecule (CD59 blood group)	Homo sapiens	37-45
11604107-7	2001	The MIN/3/60 antibody reveals a sub-population of epithelial glycans in the crypts of Lieberkuhn in normal human colon.	Polysaccharides	61-68	CD59 molecule (CD59 blood group)	Homo sapiens	4-9
11456154-2	2001	methanogenic consortia were enriched which converted various flavonoids at initial concentration of 0.5 3.0mM during stationary incubation at 37 degrees C in serum bottles with specific rates ranging from 0.025 to 0.073 micromol min(-1) (mg protein)(-1).	Flavonoids	61-71	CD59 molecule (CD59 blood group)	Homo sapiens	229-235
11569533-4	2001	In the presence of NADPH, SB-277011 was relatively stable in the presence of liver microsomes from rat, dog, cynomolgus monkey and human with an intrinsic clearance (CLi) of < 2 ml min(-1) g(-1) liver for all species.	SB 277011	26-35	CD59 molecule (CD59 blood group)	Homo sapiens	184-190
11569533-5	2001	In total liver homogenates, SB-277011 was metabolized at a similar rate in rat and dog (CLi < 2 ml min(-1) g(-1) liver) to that in liver microsomes but in cynomolgus monkey and human (CLi = 9.9 and 45 ml min(-1) g(-1) liver, respectively) the intrinsic clearance was approximately 6- and 35-fold higher, respectively, than that in liver microsomes.	SB 277011	28-37	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
11569533-5	2001	In total liver homogenates, SB-277011 was metabolized at a similar rate in rat and dog (CLi < 2 ml min(-1) g(-1) liver) to that in liver microsomes but in cynomolgus monkey and human (CLi = 9.9 and 45 ml min(-1) g(-1) liver, respectively) the intrinsic clearance was approximately 6- and 35-fold higher, respectively, than that in liver microsomes.	SB 277011	28-37	CD59 molecule (CD59 blood group)	Homo sapiens	207-213
11569533-7	2001	In the absence of NADPH, SR-277011 was rapidly cleared in liver homogenates from cynomolgus monkey and human (CLi = 7.4 and 27 ml min(-1) g(-1) liver, respectively) demonstrating that a significant pathway of metabolism of this compound was via an NADPH-independent non-microsomal oxidative route.	sr-277011	25-34	CD59 molecule (CD59 blood group)	Homo sapiens	130-136
11569533-10	2001	The in vivo pharmacokinetics showed that the plasma clearance of SB-277011 was low in rat (20 ml min(-1) kg(-1)), moderate in dog (14 ml min(-1) kg(-1)) and high in cynomolgus monkey (58 ml min(-1)kg(-1)), which is consistent with the in vitro findings and demonstrated a greater capacity for the monkey to metabolize this compound.	SB 277011	65-74	CD59 molecule (CD59 blood group)	Homo sapiens	97-103
11569533-10	2001	The in vivo pharmacokinetics showed that the plasma clearance of SB-277011 was low in rat (20 ml min(-1) kg(-1)), moderate in dog (14 ml min(-1) kg(-1)) and high in cynomolgus monkey (58 ml min(-1)kg(-1)), which is consistent with the in vitro findings and demonstrated a greater capacity for the monkey to metabolize this compound.	SB 277011	65-74	CD59 molecule (CD59 blood group)	Homo sapiens	137-143
11569533-10	2001	The in vivo pharmacokinetics showed that the plasma clearance of SB-277011 was low in rat (20 ml min(-1) kg(-1)), moderate in dog (14 ml min(-1) kg(-1)) and high in cynomolgus monkey (58 ml min(-1)kg(-1)), which is consistent with the in vitro findings and demonstrated a greater capacity for the monkey to metabolize this compound.	SB 277011	65-74	CD59 molecule (CD59 blood group)	Homo sapiens	137-143
11465229-4	2001	After a resting Doppler echocardiogram, a dobutamine infusion was started at a rate of 5 microg x kg(-1) x min(-1) and increased to 30 microg x kg(-1) x min(-1) at 15-minute intervals.	Dobutamine	42-52	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
11408153-5	2001	When an NaOH (10(-4) mol l(-1))/NaCl (0.1 mol l(-1)) solution is used as carrier solution, at a flow-rate of 1.56 ml min(-1), the sensor responds linearly in the measuring range of 10-500 microg l(-1) with a detection limit of 0.94 microg l(-1) and a throughput of 22 samples per hour (300 microl of sample volume).	Sodium Hydroxide	8-12	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
11590771-2	2001	The results showed that the ultraviolet light was more effective than fluorescent light in promoting degradation, and the degradation of NAA under ultraviolet light followed the first order kinetics with the photolysis rate constant of 1.15 x 10(-2) min-1 and half-life time (t1/2) of 60 min.	1-naphthaleneacetic acid	137-140	CD59 molecule (CD59 blood group)	Homo sapiens	250-255
11450875-7	2001	The DC task elicited the highest (p<0.01) group mean peak metabolic demand (PMD) in males (43 ml min(-1) kg(-1)) and females (42 ml min(-1) kg (-1)) who were able to maintain the endorsed work rate.	Deoxycytidine	4-6	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
11450875-7	2001	The DC task elicited the highest (p<0.01) group mean peak metabolic demand (PMD) in males (43 ml min(-1) kg(-1)) and females (42 ml min(-1) kg (-1)) who were able to maintain the endorsed work rate.	Deoxycytidine	4-6	CD59 molecule (CD59 blood group)	Homo sapiens	135-141
11408167-4	2001	Kinetic studies using agarose gel electrophoresis showed that cyclic peptide 7b and Lys-Trp-Lys possessed DNA nicking activity on natural supercoiled phi X174 DNA with nicking rate of 50.7 and 75.6 pM min(-1) at 65 degrees C, respectively, whereas cyclic peptide 7a and linear Lys-Tyr-Lys were devoid of the corresponding activity.	Peptides, Cyclic	62-76	CD59 molecule (CD59 blood group)	Homo sapiens	201-207
11408167-4	2001	Kinetic studies using agarose gel electrophoresis showed that cyclic peptide 7b and Lys-Trp-Lys possessed DNA nicking activity on natural supercoiled phi X174 DNA with nicking rate of 50.7 and 75.6 pM min(-1) at 65 degrees C, respectively, whereas cyclic peptide 7a and linear Lys-Tyr-Lys were devoid of the corresponding activity.	Lysine	84-87	CD59 molecule (CD59 blood group)	Homo sapiens	201-207
11408167-4	2001	Kinetic studies using agarose gel electrophoresis showed that cyclic peptide 7b and Lys-Trp-Lys possessed DNA nicking activity on natural supercoiled phi X174 DNA with nicking rate of 50.7 and 75.6 pM min(-1) at 65 degrees C, respectively, whereas cyclic peptide 7a and linear Lys-Tyr-Lys were devoid of the corresponding activity.	Tryptophan	88-91	CD59 molecule (CD59 blood group)	Homo sapiens	201-207
11408167-4	2001	Kinetic studies using agarose gel electrophoresis showed that cyclic peptide 7b and Lys-Trp-Lys possessed DNA nicking activity on natural supercoiled phi X174 DNA with nicking rate of 50.7 and 75.6 pM min(-1) at 65 degrees C, respectively, whereas cyclic peptide 7a and linear Lys-Tyr-Lys were devoid of the corresponding activity.	Lysine	92-95	CD59 molecule (CD59 blood group)	Homo sapiens	201-207
11408167-4	2001	Kinetic studies using agarose gel electrophoresis showed that cyclic peptide 7b and Lys-Trp-Lys possessed DNA nicking activity on natural supercoiled phi X174 DNA with nicking rate of 50.7 and 75.6 pM min(-1) at 65 degrees C, respectively, whereas cyclic peptide 7a and linear Lys-Tyr-Lys were devoid of the corresponding activity.	Lysine	92-95	CD59 molecule (CD59 blood group)	Homo sapiens	201-207
18498472-3	2001	was used at temperature of 35 degrees C, mobile phase with flow rate of 0.8 mL min(-1) was acetonitrile: water (containing 10 mm potassium dihydrogen phosphate, pH 4.0, adjusted with orthophosphoric acid) = 60 : 40 (V/V) and UV detection at 224 nm and 305 nm.	acetonitrile	91-103	CD59 molecule (CD59 blood group)	Homo sapiens	79-85
11428655-4	2001	The kinetic parameters, apparent Km, Vmax, and Hill coefficient, for the formation of 5-OHN by pooled human liver microsomes were 4012 microM, 2.66 nmol min(-1) (mg protein)(-1), and 1.65, respectively.	5-ohn	86-91	CD59 molecule (CD59 blood group)	Homo sapiens	153-159
11337833-6	2001	For conditions with 0.048% Pd/Fe, the rate constants are 0.0215, 0.0155 and 0.0112 min-1 for o-, m-, p-chlorophenol, respectively.	Palladium	27-29	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
11337833-6	2001	For conditions with 0.048% Pd/Fe, the rate constants are 0.0215, 0.0155 and 0.0112 min-1 for o-, m-, p-chlorophenol, respectively.	Iron	30-32	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
11337833-6	2001	For conditions with 0.048% Pd/Fe, the rate constants are 0.0215, 0.0155 and 0.0112 min-1 for o-, m-, p-chlorophenol, respectively.	Chlorophenols	103-115	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
18968291-5	2001	The best sample loading flow rate was 4.0 ml min(-1) for the activated carbon and 2.0 ml min(-1) for C(18) and the polyurethane foam, while the best elution flow rate was 1.0 ml min(-1) (activated carbon) and 0.6 ml min(-1) (C(18) and foam).	Carbon	101-102	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
18968291-5	2001	The best sample loading flow rate was 4.0 ml min(-1) for the activated carbon and 2.0 ml min(-1) for C(18) and the polyurethane foam, while the best elution flow rate was 1.0 ml min(-1) (activated carbon) and 0.6 ml min(-1) (C(18) and foam).	Carbon	101-102	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
18968291-5	2001	The best sample loading flow rate was 4.0 ml min(-1) for the activated carbon and 2.0 ml min(-1) for C(18) and the polyurethane foam, while the best elution flow rate was 1.0 ml min(-1) (activated carbon) and 0.6 ml min(-1) (C(18) and foam).	Carbon	101-102	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
11407580-3	2001	Iodide was converted to iodine, then sequestered with starch, and separated from the matrix using a Shim-pack DIOL-150 (250 x 7.9 mm) size exclusion column with methanol-0.01 mol l(-1) aqueous phosphoric acid (10:90, v/v) as mobile phase at 1.2 ml min(-1) and UV detection at 224 nm.	Iodides	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	248-254
11575339-5	2001	Anaesthetic usage for a 70 kg patient was 0.44e(-0.51t)+0.044e(-0.013t)+0.058e(-0.00098t) ml min(-1) of liquid isoflurane, where t is duration of anaesthesia in minutes.	Isoflurane	111-121	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
11368553-10	2001	Optimal production of ONOO(-) was assessed with DPTA/NO and diethylenetriamine NONOate (initial (*)NO generation rates of 0.76 and 0.08 microM min(-1), respectively).	onoo	22-26	CD59 molecule (CD59 blood group)	Homo sapiens	143-149
11788859-1	2001	The dynamic phase diagrams of the water-ethylene glycol (EG) system have been plotted at the warming rate of 0.4 degrees C/min(-1) after cooling of samples down to -196 degrees C by quenching in liquid nitrogen or slow cooling at the rate of approximately 0.15 degrees C/min(-1).	Water	34-39	CD59 molecule (CD59 blood group)	Homo sapiens	123-129
11788859-1	2001	The dynamic phase diagrams of the water-ethylene glycol (EG) system have been plotted at the warming rate of 0.4 degrees C/min(-1) after cooling of samples down to -196 degrees C by quenching in liquid nitrogen or slow cooling at the rate of approximately 0.15 degrees C/min(-1).	eg	57-59	CD59 molecule (CD59 blood group)	Homo sapiens	123-129
11424471-4	2001	Immediately after ECT, the heart rate dropped from 56 to 19 beats.min-1, which was remedied by intravenous atropine.	Atropine	107-115	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
11394298-7	2001	The collection efficiency of H2O2 was higher than 98% at an air flow rate of 1.0 l min-1.	Hydrogen Peroxide	29-33	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
11424471-6	2001	However, the SpO2 decreased to 84-88% under oxygen administration by mask at a rate of 3 l.min-1.	Oxygen	44-50	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
12528518-2	2001	METHOD: A RP-HPLC method was set up, using Hypersil-18 column, acetonitrile: water(30:70) as mobile phase with a flow rate of 0.8 ml.min-1.	Water	77-82	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
11358255-7	2001	The hexaamine-based potentiometric electrodes had a 1-s response time at 1 ml min(-1) flow-rates.	hexaamine	4-13	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
11254474-6	2001	min(-1) (GLY), P < 0.05] and during exercise at both intensities [45%: 0.63 +/- 0.14 (CON) vs. 0.04 +/- 0.12 (GLY); 65%: 0.73 +/- 0.14 (CON) vs. 0.04 +/- 0.17 mg. kg(-1).	Glycine	9-12	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
11359587-6	2001	Adverse respiratory events (RR < 10.min-1 or SpO2 < 90%) occurred significantly more in the propofol/remifentanil group.	Propofol	98-106	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
11359587-6	2001	Adverse respiratory events (RR < 10.min-1 or SpO2 < 90%) occurred significantly more in the propofol/remifentanil group.	Remifentanil	107-119	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
11348089-5	2001	The optimized gas and water flow rates were approximately 1.2 and approximately 14 mL min(-1), respectively, giving a response time of less than 15 min and a CO-extraction yield of approximately 80%.	Water	22-27	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
11260405-7	2001	Seven subjects had an RPF response to captopril that was accentuated (90 +/- 13 mL/min/1.73 m2), while five had a response that was normal (-4 +/- 9).	Captopril	38-47	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
11248136-13	2001	Renal boron clearance measured over the initial 2 h, the most complete urine collection period, was 68.30ml/min/1.73 m(2) for pregnant subjects and 54.31ml/min/1.73 m(2) for nonpregnant subjects.	Boron	6-11	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
11102445-11	2001	Direct transport studies using [(3)H]estrone 3-sulfate confirmed that the conjugated estrogen could be efficiently transported (K(m) = 0.73 microm, V(max) = 440 pmol mg(-)1 protein min(-)1), but only in the presence of either GSH or the nonreducing alkyl derivative, S-methyl GSH.	3-sulfate	45-54	CD59 molecule (CD59 blood group)	Homo sapiens	181-188
11102445-11	2001	Direct transport studies using [(3)H]estrone 3-sulfate confirmed that the conjugated estrogen could be efficiently transported (K(m) = 0.73 microm, V(max) = 440 pmol mg(-)1 protein min(-)1), but only in the presence of either GSH or the nonreducing alkyl derivative, S-methyl GSH.	Glutathione	226-229	CD59 molecule (CD59 blood group)	Homo sapiens	181-188
11102445-11	2001	Direct transport studies using [(3)H]estrone 3-sulfate confirmed that the conjugated estrogen could be efficiently transported (K(m) = 0.73 microm, V(max) = 440 pmol mg(-)1 protein min(-)1), but only in the presence of either GSH or the nonreducing alkyl derivative, S-methyl GSH.	Glutathione	276-279	CD59 molecule (CD59 blood group)	Homo sapiens	181-188
11573525-7	2001	The median dose of remifentanil for maintenance of adequate anaesthesia (excluding the initial bolus dose) in the four groups was 0.21, 0.15, 0.11 and 0.13 microg kg(-1) min(-1) respectively (P=0.0026).	Remifentanil	19-31	CD59 molecule (CD59 blood group)	Homo sapiens	170-176
11248707-6	2001	By employing metal-chelate affinity chromatography under native conditions, the enzymes were purified without detergents to a specific activity of more than 100 micromol x min(-1) x mg(-1) at pH optimum of 8.0--8.1.	Metals	13-18	CD59 molecule (CD59 blood group)	Homo sapiens	172-178
11277381-8	2001	Reducing glucose infusion resulted in a steep increase in glycogenolysis and gluconeogenesis, maintaining total glucose turnover (production plus infusion) constant at +/-9 mg x kg(-1) x min(-1) (+/-60% gluconeogenesis, +/-40% glycogenolysis).	Glucose	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	187-193
11336340-4	2001	The rates of formation and dissociation of iron(II) tris-(1,10-phenanthrolinate) at a level of n x 10(-8) mol L(-1) were found to be (2.05+/-0.05) x 10(-2) min(-1) and (3.0+/-0.1) x 10(-3) min(-1), respectively.	iron(ii) tris-(1,10-phenanthrolinate)	43-80	CD59 molecule (CD59 blood group)	Homo sapiens	156-162
11336340-4	2001	The rates of formation and dissociation of iron(II) tris-(1,10-phenanthrolinate) at a level of n x 10(-8) mol L(-1) were found to be (2.05+/-0.05) x 10(-2) min(-1) and (3.0+/-0.1) x 10(-3) min(-1), respectively.	iron(ii) tris-(1,10-phenanthrolinate)	43-80	CD59 molecule (CD59 blood group)	Homo sapiens	189-195
11317155-7	2001	It was observed that the clonidine treatment induced a lesser postexercise proteinuria (213 +/- 28 versus 298 +/- 55 mg.min-1) and albuminuria (71.8 +/- 16.3 versus 116.8 +/- 34.2 mg.min-1) when compared to the placebo test.	Clonidine	25-34	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
11317155-7	2001	It was observed that the clonidine treatment induced a lesser postexercise proteinuria (213 +/- 28 versus 298 +/- 55 mg.min-1) and albuminuria (71.8 +/- 16.3 versus 116.8 +/- 34.2 mg.min-1) when compared to the placebo test.	Clonidine	25-34	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
11355603-4	2001	The most widely accepted criterion is a level of creatinine clearance estimated by the Cockcroft-Gault formula between 7 and 10 mL/min/1.73 m2.	Creatinine	49-59	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
11465392-5	2001	The rate (pmol min(-1) mg(-1)) of (-)-salbutamol sulphation was 109 +/- 27 (adult) and 117 +/- 34 (foetus; p = (0.144) and that of minoxidil sulphation was 202 +/- 38 (adult) and 108 +/- 44 (foetus; p = 0.001).	Albuterol	34-48	CD59 molecule (CD59 blood group)	Homo sapiens	15-21
11254474-7	2001	min(-1) (GLY), P < 0.05].	Glycine	9-12	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
11350278-4	2001	theophylline decreased (P < 0.003) femoral artery blood flow (FaBF) by approximately 20%, i.e. from 3.6 +/- 0.5 to 2.9 +/- 0.5 L min(-1), and leg vascular conductance (VC) from 33.4 +/- 9.1 to 27.7 +/- 8.5 mL min-1 mmHg-1, whereas heart rate (HR), mean arterial pressure (MAP), leg oxygen uptake and lactate release remained unaltered (P = n.s.).	Theophylline	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	132-138
11350278-5	2001	Bolus injections of adenosine (2.5 mg) at rest rapidly increased (P < 0.05) FaBF from 0.3 +/- 0.03 L min(-1) to a 15-fold peak elevation (P < 0.05) at 4.1 +/- 0.5 L min(-1).	Adenosine	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
11350278-5	2001	Bolus injections of adenosine (2.5 mg) at rest rapidly increased (P < 0.05) FaBF from 0.3 +/- 0.03 L min(-1) to a 15-fold peak elevation (P < 0.05) at 4.1 +/- 0.5 L min(-1).	Adenosine	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	171-177
11350278-6	2001	Continuous infusion of adenosine at rest and during one-legged exercise at approximately 62% of peak power output increased (P < 0.05) FaBF dose-dependently to level off (P = ns) at 8.3 +/- 1.0 and 8.2 +/- 1.4 L min(-1), respectively.	Adenosine	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	215-221
11161937-4	2001	The response of coronary blood flow velocity to intracoronary infusion of acetylcholine (1.8 microg x min(-1)) and adenosine (270 microg x min(-1)) was assessed using a Doppler wire positioned in an epicardial coronary branch.	Acetylcholine	74-87	CD59 molecule (CD59 blood group)	Homo sapiens	102-109
11180111-1	2001	The glycosylphosphatidylinositol (GPI)-anchored protein CD59 and the ganglioside GM1 are present on lipid rafts that can be isolated in a detergent-insoluble membrane (DIM) fraction.	Glycosylphosphatidylinositols	4-32	CD59 molecule (CD59 blood group)	Homo sapiens	56-60
11180111-1	2001	The glycosylphosphatidylinositol (GPI)-anchored protein CD59 and the ganglioside GM1 are present on lipid rafts that can be isolated in a detergent-insoluble membrane (DIM) fraction.	Glycosylphosphatidylinositols	34-37	CD59 molecule (CD59 blood group)	Homo sapiens	56-60
11180111-7	2001	Aggregation of GM1, CD59 or TCR/CD3 increased tyrosine phosphorylation but only in the latter case was a significant increase observed in both tyrosine phosphorylation and recruitment of elements of the signaling machinery in DIM.	Tyrosine	46-54	CD59 molecule (CD59 blood group)	Homo sapiens	20-24
11180111-7	2001	Aggregation of GM1, CD59 or TCR/CD3 increased tyrosine phosphorylation but only in the latter case was a significant increase observed in both tyrosine phosphorylation and recruitment of elements of the signaling machinery in DIM.	Tyrosine	143-151	CD59 molecule (CD59 blood group)	Homo sapiens	20-24
11680875-5	2001	CD59, for example, has over 100 different sugars at one N-linked glycosylation site.	Sugars	42-48	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
11167470-4	2001	The median dosage of remifentanil required in the last three groups was 0.21, 0.25 and 0.34 microg x kg(-1) x min(-1), respectively (p < 0.05).	Remifentanil	21-33	CD59 molecule (CD59 blood group)	Homo sapiens	110-116
11121275-4	2001	The process follows a first-order kinetic equation and the rate of uptake was found to be 2.40x10(-2) min(-1) at 30 degrees C, 2.5 pH, 0.5x10(-4) M Cr(VI) concentration, and 0.01 M NaClO(4) ionic strength.	Chromium	148-150	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
11121275-4	2001	The process follows a first-order kinetic equation and the rate of uptake was found to be 2.40x10(-2) min(-1) at 30 degrees C, 2.5 pH, 0.5x10(-4) M Cr(VI) concentration, and 0.01 M NaClO(4) ionic strength.	Sodium Hypochlorite	181-186	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
12162583-8	2001	The greatest oxygen uptake relative to body mass was found in the modern pentathlonists (73.22 ml x kg(-1) x min(-1)) and the lowest one (59.79) in the water polo players.	Oxygen	13-19	CD59 molecule (CD59 blood group)	Homo sapiens	109-115
11135717-8	2001	Before and during the second rekindling, remifentanil 0.10 microg x kg(-1) x min(-1) or saline-placebo was infused for 35 min.	Remifentanil	41-53	CD59 molecule (CD59 blood group)	Homo sapiens	77-83
11205516-4	2001	To optimise the operating conditions methyl 4-formylbenzoate, premixed with sodium methoxide, was reacted with 2-nitrobenzyl-triphenylphosphonium bromide in dry degassed MeOH using flow conditions for both reagents of 0.40 microL min-1 for 20 min.	METHYL 4-FORMYLBENZOATE	37-60	CD59 molecule (CD59 blood group)	Homo sapiens	230-235
11205516-4	2001	To optimise the operating conditions methyl 4-formylbenzoate, premixed with sodium methoxide, was reacted with 2-nitrobenzyl-triphenylphosphonium bromide in dry degassed MeOH using flow conditions for both reagents of 0.40 microL min-1 for 20 min.	2-nitrobenzyl-triphenylphosphonium bromide	111-153	CD59 molecule (CD59 blood group)	Homo sapiens	230-235
11205516-4	2001	To optimise the operating conditions methyl 4-formylbenzoate, premixed with sodium methoxide, was reacted with 2-nitrobenzyl-triphenylphosphonium bromide in dry degassed MeOH using flow conditions for both reagents of 0.40 microL min-1 for 20 min.	Methanol	170-174	CD59 molecule (CD59 blood group)	Homo sapiens	230-235
11159693-9	2001	Acetazolamide infusions increased forearm blood flow from 2.41+/-0.17 to 2.99+/-0.18, 4.09+/-0.26 and 6.77+/-0.49 ml min(-1) dl(-1) in the infused forearm (P:<0.001), with no significant changes in the non-infused forearm, blood pressure or heart rate.	Acetazolamide	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
11170506-3	2001	Incubation of OTA with rat or human liver microsomes fortified with NADPH resulted in formation of 4-(R)-hydroxyochratoxin A at low rates [10-25 pmol min(-1) (mg of protein)(-1)].	NADP	68-73	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
11353933-13	2001	In the mesenteric circulation, dopamine at 32 microg kg-1 min-1 increased portal venous flow and total hepatic blood flow and oxygen delivery, and decreased MVRI; epinephrine had no effect on these variables.	Dopamine	31-39	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
11353933-13	2001	In the mesenteric circulation, dopamine at 32 microg kg-1 min-1 increased portal venous flow and total hepatic blood flow and oxygen delivery, and decreased MVRI; epinephrine had no effect on these variables.	Oxygen	126-132	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
11353933-14	2001	Epinephrine increased hepatic arterial flow at 0.2 microg kg-1 min-1; dopamine had no effect on hepatic arterial flow at any dose.	Epinephrine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
11429627-5	2001	The rate of carbohydrate oxidation was higher (micromol kg-1 min-1: CHO, 243 +/- 39 and CHO + CAF, 239 +/- 30 vs.	Carbohydrates	12-24	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
11429627-5	2001	The rate of carbohydrate oxidation was higher (micromol kg-1 min-1: CHO, 243 +/- 39 and CHO + CAF, 239 +/- 30 vs.	CAV protocol	68-71	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
11429627-7	2001	and the rate of fat oxidation lower (micromol kg-1 min-1: CHO, 19 +/- 8 and CHO + CAF, 22 +/- 7 vs.	CAV protocol	58-61	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
11135083-5	2001	RESULTS: Concentration-dependent renal clearance of PAH was observed at plasma concentrations> 100 mg/L; renal clearances were 442 +/- 131 (mean +/- SD), 423 +/- 94, 233 +/- 45, and 152 +/- 18 mL/min/1.73 m2 at plasma concentrations of 18 +/- 2, 92 +/- 5, 291 +/- 47 and 789 +/- 28 mg/L, respectively.	p-Aminohippuric Acid	52-55	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
11135083-7	2001	The unbound renal clearance and tubular secretory clearance of famotidine were 384 +/- 70 and 329 +/- 78 mL/min/1.73 m2, respectively, and were not significantly correlated with the unbound plasma concentrations, which ranged from 126 to 2659 ng/mL.	Famotidine	63-73	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
11211748-4	2001	Anesthesia was maintained with about 1% of sevoflurane, with nitrous oxide 3 l.min-1 in oxygen 3 l.min-1.	Oxygen	88-94	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
11262979-4	2001	Intrinsic exchange rates for denatured CspA in 90% DMSO/10% D2O (pH* 4.5) were sufficiently slow (approximately 1 x 10(-3) min-1) to enable quantification of NMR signal intensity decays due to H/D exchange in the fibrils.	cspa	39-43	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
11262979-4	2001	Intrinsic exchange rates for denatured CspA in 90% DMSO/10% D2O (pH* 4.5) were sufficiently slow (approximately 1 x 10(-3) min-1) to enable quantification of NMR signal intensity decays due to H/D exchange in the fibrils.	Deuterium Oxide	60-63	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
11262979-5	2001	Hydrogen exchange rate constants for CspA fibrils were found to vary less than 3-fold from a mean value of 5 x 10(-5) min-1.	Hydrogen	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
11207020-6	2001	The mean increases in morning peak expiratory flow (PEF primary variable) and evening PEF over the 3-month treatment period were statistically significantly higher with formoterol: +25.7 and +24.1 l min(-1), respectively vs. +4.5 and +0.5 l min(-1) respectively with ODS.	Formoterol Fumarate	169-179	CD59 molecule (CD59 blood group)	Homo sapiens	199-205
11207020-6	2001	The mean increases in morning peak expiratory flow (PEF primary variable) and evening PEF over the 3-month treatment period were statistically significantly higher with formoterol: +25.7 and +24.1 l min(-1), respectively vs. +4.5 and +0.5 l min(-1) respectively with ODS.	Formoterol Fumarate	169-179	CD59 molecule (CD59 blood group)	Homo sapiens	241-247
11394278-3	2001	The best pilot plant operational condition was obtained applying only 4.0 g/m3 (S*) with Vh around 18 cm.min-1 for treatment of water coagulated with a Al2(SO4)3 dosage of 40 mg.l-1.	Water	128-133	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
11394278-3	2001	The best pilot plant operational condition was obtained applying only 4.0 g/m3 (S*) with Vh around 18 cm.min-1 for treatment of water coagulated with a Al2(SO4)3 dosage of 40 mg.l-1.	aluminum sulfate	152-161	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
11163984-6	2000	Gly-[3H]L-Pro uptake had a substantial active concentration-dependent component (Km of 0.39 +/- 0.02 mM, Vmax of 0.98 +/- 0.04 nmol min(-1) (mg protein)(-1).	Glycine	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	132-138
11163984-6	2000	Gly-[3H]L-Pro uptake had a substantial active concentration-dependent component (Km of 0.39 +/- 0.02 mM, Vmax of 0.98 +/- 0.04 nmol min(-1) (mg protein)(-1).	3h]l-pro	5-13	CD59 molecule (CD59 blood group)	Homo sapiens	132-138
11136294-6	2000	RESULTS: BZD N-oxide formation rates in HLM followed Michaelis-Menten kinetics (mean Km = 64.0 microM, mean Vmax = 6.9 nmol mg-1 protein min-1; n = 35).	Benzydamine	9-12	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
11136294-6	2000	RESULTS: BZD N-oxide formation rates in HLM followed Michaelis-Menten kinetics (mean Km = 64.0 microM, mean Vmax = 6.9 nmol mg-1 protein min-1; n = 35).	n-oxide	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
11132744-5	2000	RESULTS: Total resistive work spent on the upstream segment of the nasal route per minute (Wn) (J x min(-1)) was greater during midazolam sedation (3.6 +/- 2.9) than while awake (1.6 +/- 0.9) and after flumazenil antagonism (1.7 +/- 0.6), respectively (mean +/- SD) (P < 0.05).	Midazolam	128-137	CD59 molecule (CD59 blood group)	Homo sapiens	100-107
11132744-5	2000	RESULTS: Total resistive work spent on the upstream segment of the nasal route per minute (Wn) (J x min(-1)) was greater during midazolam sedation (3.6 +/- 2.9) than while awake (1.6 +/- 0.9) and after flumazenil antagonism (1.7 +/- 0.6), respectively (mean +/- SD) (P < 0.05).	Flumazenil	202-212	CD59 molecule (CD59 blood group)	Homo sapiens	100-107
11153615-12	2000	Endogenous glucose production was markedly increased in the patients (1.95 +/- 0.26 vs. 5.3 +/- 3.0 mg x kg(-1) x min(-1); p < .05 [10.8 +/- 1.4 vs. 29.4 +/- 16.7 micromol x kg(-1) x min(-1)]), whereas net carbohydrate oxidation was not different (1.7 +/- 0.5 vs. 1.3 +/- 0.3 mg x kg(-1) x min(-1) [9.4 +/- 2.8 vs. 7.2 +/- 1.7 micromol x kg(-1) x min(-1)]).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	114-120
11153615-12	2000	Endogenous glucose production was markedly increased in the patients (1.95 +/- 0.26 vs. 5.3 +/- 3.0 mg x kg(-1) x min(-1); p < .05 [10.8 +/- 1.4 vs. 29.4 +/- 16.7 micromol x kg(-1) x min(-1)]), whereas net carbohydrate oxidation was not different (1.7 +/- 0.5 vs. 1.3 +/- 0.3 mg x kg(-1) x min(-1) [9.4 +/- 2.8 vs. 7.2 +/- 1.7 micromol x kg(-1) x min(-1)]).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	186-192
11153615-12	2000	Endogenous glucose production was markedly increased in the patients (1.95 +/- 0.26 vs. 5.3 +/- 3.0 mg x kg(-1) x min(-1); p < .05 [10.8 +/- 1.4 vs. 29.4 +/- 16.7 micromol x kg(-1) x min(-1)]), whereas net carbohydrate oxidation was not different (1.7 +/- 0.5 vs. 1.3 +/- 0.3 mg x kg(-1) x min(-1) [9.4 +/- 2.8 vs. 7.2 +/- 1.7 micromol x kg(-1) x min(-1)]).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	186-192
11153615-12	2000	Endogenous glucose production was markedly increased in the patients (1.95 +/- 0.26 vs. 5.3 +/- 3.0 mg x kg(-1) x min(-1); p < .05 [10.8 +/- 1.4 vs. 29.4 +/- 16.7 micromol x kg(-1) x min(-1)]), whereas net carbohydrate oxidation was not different (1.7 +/- 0.5 vs. 1.3 +/- 0.3 mg x kg(-1) x min(-1) [9.4 +/- 2.8 vs. 7.2 +/- 1.7 micromol x kg(-1) x min(-1)]).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	186-192
11118008-5	2000	The rate of glucose production was twice as high in the diabetic subjects as in control subjects (0.70 +/- 0.05 vs. 0.36 +/- 0.03 mmol x m(-2) min(-1), P < 0.0001).	Glucose	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	143-149
11118008-6	2000	Metformin reduced that rate by 24% (to 0.53 +/- 0.03 mmol x m(-2) x min(-1), P = 0.0009) and fasting plasma glucose concentration by 30% (to 10.8 +/- 0.9 mmol/l, P = 0.0002).	Metformin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
11118008-8	2000	By the 2H2O method, there was a twofold increase in rates of gluconeogenesis in diabetic subjects (0.42 +/- 0.04 mmol m(-2) x min(-1), which decreased by 33% after metformin treatment (0.28 +/- 0.03 mmol x m(-2) x min(-1), P = 0.0002).	2h2o	7-11	CD59 molecule (CD59 blood group)	Homo sapiens	126-132
11118008-8	2000	By the 2H2O method, there was a twofold increase in rates of gluconeogenesis in diabetic subjects (0.42 +/- 0.04 mmol m(-2) x min(-1), which decreased by 33% after metformin treatment (0.28 +/- 0.03 mmol x m(-2) x min(-1), P = 0.0002).	2h2o	7-11	CD59 molecule (CD59 blood group)	Homo sapiens	214-220
11118013-6	2000	The oxidation of plasma-derived fatty acids was significantly lower in type 2 diabetic subjects during both conditions (P < 0.05, baseline vs. exercise [40-60 min]; type 2 diabetes 4.2 +/- 0.5 vs. 14.1 +/- 1.9 micromol x kg(-1) FFM x min(-1) and control 6.2 +/- 0.6 vs. 20.4 +/- 1.9 micromol x kg(-1) FFM x min(-1)), whereas the oxidation of triglyceride-derived fatty acids was higher (P < 0.05).	Fatty Acids	32-43	CD59 molecule (CD59 blood group)	Homo sapiens	237-243
11118013-6	2000	The oxidation of plasma-derived fatty acids was significantly lower in type 2 diabetic subjects during both conditions (P < 0.05, baseline vs. exercise [40-60 min]; type 2 diabetes 4.2 +/- 0.5 vs. 14.1 +/- 1.9 micromol x kg(-1) FFM x min(-1) and control 6.2 +/- 0.6 vs. 20.4 +/- 1.9 micromol x kg(-1) FFM x min(-1)), whereas the oxidation of triglyceride-derived fatty acids was higher (P < 0.05).	Fatty Acids	32-43	CD59 molecule (CD59 blood group)	Homo sapiens	310-316
11056001-2	2000	Protectin (CD59) is a glycosylphosphatidylinositol (GPI)-anchored cell membrane glycoprotein, acting as terminal regulator of C cascade, which is heterogeneously expressed in melanomas and represents the main restriction factor of C-mediated lysis of melanoma cells.	Glycosylphosphatidylinositols	22-50	CD59 molecule (CD59 blood group)	Homo sapiens	0-9
11056001-2	2000	Protectin (CD59) is a glycosylphosphatidylinositol (GPI)-anchored cell membrane glycoprotein, acting as terminal regulator of C cascade, which is heterogeneously expressed in melanomas and represents the main restriction factor of C-mediated lysis of melanoma cells.	Glycosylphosphatidylinositols	22-50	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
11056001-2	2000	Protectin (CD59) is a glycosylphosphatidylinositol (GPI)-anchored cell membrane glycoprotein, acting as terminal regulator of C cascade, which is heterogeneously expressed in melanomas and represents the main restriction factor of C-mediated lysis of melanoma cells.	Glycosylphosphatidylinositols	52-55	CD59 molecule (CD59 blood group)	Homo sapiens	0-9
11056001-2	2000	Protectin (CD59) is a glycosylphosphatidylinositol (GPI)-anchored cell membrane glycoprotein, acting as terminal regulator of C cascade, which is heterogeneously expressed in melanomas and represents the main restriction factor of C-mediated lysis of melanoma cells.	Glycosylphosphatidylinositols	52-55	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
11071659-8	2000	In agreement with this finding, azide plus 2-deoxy-D-glucose, 2 metabolic blockers, also induced a rapid L-selectin shedding (65% +/- 8%) without affecting the neutrophil viability, activation, or expression level of other surface molecules with soluble isoforms such as CD16 and CD59.	Azides	32-37	CD59 molecule (CD59 blood group)	Homo sapiens	280-284
11071659-8	2000	In agreement with this finding, azide plus 2-deoxy-D-glucose, 2 metabolic blockers, also induced a rapid L-selectin shedding (65% +/- 8%) without affecting the neutrophil viability, activation, or expression level of other surface molecules with soluble isoforms such as CD16 and CD59.	Deoxyglucose	43-60	CD59 molecule (CD59 blood group)	Homo sapiens	280-284
11680875-5	2001	CD59, for example, has over 100 different sugars at one N-linked glycosylation site.	Nitrogen	56-57	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
11094580-11	2000	The total blood clearance of clevidipine is extremely high (0.055 litres min-1 kg-1).	clevidipine	29-40	CD59 molecule (CD59 blood group)	Homo sapiens	73-83
11052916-6	2000	During sodium nitroprusside infusion, forearm noradrenaline spillover increased from 1.1+/-0.3 to 2.2+/-1.0 pmol x min(-1) x 100 ml(-1) (P<0.05), whereas the forearm noradrenaline appearance rate was unchanged.	Nitroprusside	7-27	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
11052916-6	2000	During sodium nitroprusside infusion, forearm noradrenaline spillover increased from 1.1+/-0.3 to 2.2+/-1.0 pmol x min(-1) x 100 ml(-1) (P<0.05), whereas the forearm noradrenaline appearance rate was unchanged.	Norepinephrine	46-59	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
11052916-7	2000	Lower-body negative pressure did not affect the forearm noradrenaline spillover rate, but increased the forearm noradrenaline appearance rate from 3.4+/-0.4 pmol x min(-1) x 100 ml(-1) at baseline to 5.0+/-0.9 pmol x min(-1) x 100 ml(-1) (P<0.05).	Norepinephrine	112-125	CD59 molecule (CD59 blood group)	Homo sapiens	164-170
11262607-1	2000	PURPOSE: The decay accelerating factor (DAF or CD55) and the membrane inhibitor of reactive lysis (MIRL or CD59), two complement regulatory proteins that protect self cells from autologous complement-mediated injury, are attached to corneal and cqonjunctival epithelial cells by glycosylphos-phatidylinositol (GPI) anchors.	Glycosylphosphatidylinositols	279-308	CD59 molecule (CD59 blood group)	Homo sapiens	61-97
11262607-1	2000	PURPOSE: The decay accelerating factor (DAF or CD55) and the membrane inhibitor of reactive lysis (MIRL or CD59), two complement regulatory proteins that protect self cells from autologous complement-mediated injury, are attached to corneal and cqonjunctival epithelial cells by glycosylphos-phatidylinositol (GPI) anchors.	Glycosylphosphatidylinositols	279-308	CD59 molecule (CD59 blood group)	Homo sapiens	99-103
11262607-1	2000	PURPOSE: The decay accelerating factor (DAF or CD55) and the membrane inhibitor of reactive lysis (MIRL or CD59), two complement regulatory proteins that protect self cells from autologous complement-mediated injury, are attached to corneal and cqonjunctival epithelial cells by glycosylphos-phatidylinositol (GPI) anchors.	Glycosylphosphatidylinositols	279-308	CD59 molecule (CD59 blood group)	Homo sapiens	107-111
11262607-1	2000	PURPOSE: The decay accelerating factor (DAF or CD55) and the membrane inhibitor of reactive lysis (MIRL or CD59), two complement regulatory proteins that protect self cells from autologous complement-mediated injury, are attached to corneal and cqonjunctival epithelial cells by glycosylphos-phatidylinositol (GPI) anchors.	Glycosylphosphatidylinositols	310-313	CD59 molecule (CD59 blood group)	Homo sapiens	61-97
11262607-1	2000	PURPOSE: The decay accelerating factor (DAF or CD55) and the membrane inhibitor of reactive lysis (MIRL or CD59), two complement regulatory proteins that protect self cells from autologous complement-mediated injury, are attached to corneal and cqonjunctival epithelial cells by glycosylphos-phatidylinositol (GPI) anchors.	Glycosylphosphatidylinositols	310-313	CD59 molecule (CD59 blood group)	Homo sapiens	99-103
11262607-1	2000	PURPOSE: The decay accelerating factor (DAF or CD55) and the membrane inhibitor of reactive lysis (MIRL or CD59), two complement regulatory proteins that protect self cells from autologous complement-mediated injury, are attached to corneal and cqonjunctival epithelial cells by glycosylphos-phatidylinositol (GPI) anchors.	Glycosylphosphatidylinositols	310-313	CD59 molecule (CD59 blood group)	Homo sapiens	107-111
11187979-9	2000	Following ACZ administration, the peripheral chemosensitivity was blunted (control vs. ACZ treatment: 3.66 +/- 0.92 vs. 1.33 +/- 0.46 l x min(-1) (mmHg CO2)(-1), P < 0.05).	Acetazolamide	10-13	CD59 molecule (CD59 blood group)	Homo sapiens	138-144
11187979-9	2000	Following ACZ administration, the peripheral chemosensitivity was blunted (control vs. ACZ treatment: 3.66 +/- 0.92 vs. 1.33 +/- 0.46 l x min(-1) (mmHg CO2)(-1), P < 0.05).	Acetazolamide	87-90	CD59 molecule (CD59 blood group)	Homo sapiens	138-144
11193277-6	2000	METHODS: Dopamine doses of 0, 2, 4, 6 and 0 microg x kg(-1) x min(-1) were given consecutively for 1 h each.	Dopamine	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
11193277-10	2000	The median norepinephrine dose at the start of the study was 0.29 microg x kg(-1) x min(-1) (range 0.07-0.48 microg x kg(-1) x min(-1)).	Norepinephrine	11-25	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
11193277-15	2000	Sodium excretion and diuresis increased for all doses, accompanied by an increase of fractional sodium excretion at the 4 and 6 microg x kg(-1) x min(-1) doses of dopamine.	Dopamine	163-171	CD59 molecule (CD59 blood group)	Homo sapiens	146-152
11193277-18	2000	CONCLUSION: During norepinephrine infusion, increasing doses of dopamine from 2 to 6 microg x kg(-1) x min(-1) augments CO, diuresis and sodium excretion in patients treated for septic shock, without changes in creatinine clearance.	Dopamine	64-72	CD59 molecule (CD59 blood group)	Homo sapiens	103-109
11193277-18	2000	CONCLUSION: During norepinephrine infusion, increasing doses of dopamine from 2 to 6 microg x kg(-1) x min(-1) augments CO, diuresis and sodium excretion in patients treated for septic shock, without changes in creatinine clearance.	Sodium	137-143	CD59 molecule (CD59 blood group)	Homo sapiens	103-109
11193277-18	2000	CONCLUSION: During norepinephrine infusion, increasing doses of dopamine from 2 to 6 microg x kg(-1) x min(-1) augments CO, diuresis and sodium excretion in patients treated for septic shock, without changes in creatinine clearance.	Creatinine	211-221	CD59 molecule (CD59 blood group)	Homo sapiens	103-109
11193277-19	2000	Higher doses of dopamine (4 and 6 microg x kg(-1) x min(-1)) also induce an increase in heart rate.	Dopamine	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	52-58
11063318-5	2000	The valine transport system in porcine mammary tissue had a Km of 0.64 mM, a Vmax of 1.84 mmol-kg cell water(-1) 30 min(-l), and a Kd (diffusion constant) of 1.16 L x kg cell water(-1) x 30 min(-1).	Valine	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	190-196
11012561-2	2000	METHODS: Four patients received a GTN tape following intravenous administration of 0.1 microg kg-1 min-1 GTN, and the other four patients received two GTN tapes following intravenous administration of 0.2 microg kg-1 min-1 GTN.	Nitroglycerin	34-37	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
11064606-4	2000	Clearance was 7.4 (1.9) ml min-1 kg-1 and the terminal half-life 3.2 (0.8) h. Thus, the free plasma concentrations of ropivacaine were well below those associated with toxic symptoms in adults and the capacity to eliminate ropivacaine seems to be well developed in this age group.	Ropivacaine	118-129	CD59 molecule (CD59 blood group)	Homo sapiens	27-37
11016453-4	2000	Endogenous glucose production (EGP) was 22 +/- 2, 18 +/- 2, 17 +/- 2, and 22 +/- 2 pmol x kg(-1) lean body mass (LBM) x min(-1) (P < 0.05, days 5 and 10 vs. baseline).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	120-126
11092568-3	2000	The metabolic clearance rates (Vmax/Km) of saquinavir, nelfinavir, and indinavir were 170.9 +/- 10.9, 126.1 +/- 4-4, and 73.0 +/- 2.0 microL min(-1) (mg protein)(-1), respectively.	Saquinavir	43-53	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
11092568-3	2000	The metabolic clearance rates (Vmax/Km) of saquinavir, nelfinavir, and indinavir were 170.9 +/- 10.9, 126.1 +/- 4-4, and 73.0 +/- 2.0 microL min(-1) (mg protein)(-1), respectively.	Indinavir	71-80	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
11120915-7	2000	During exercise, the mean oxygen consumption levels were 1.70 +/- 0.10/ x min(-1) for L-SS and 1.75 +/- 0.11/ x min(-1) for H-SS (p = 0.07), respectively.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	74-80
11013013-2	2000	Our earlier immunohistochemical studies have shown that the deposition of the membrane attack complex (MAC) of complement is associated with the loss of protectin (CD59), a glycosyl-phosphatidylinositol (GPI)-anchored sarcolemmal regulator of MAC, from the human and rat infarcted myocardium.	Glycosylphosphatidylinositols	173-202	CD59 molecule (CD59 blood group)	Homo sapiens	153-162
11062872-2	2000	The first-order rate constants for Th(IV) beta-diketonate degradation were found to be (9.3 +/- 0.8) x 10(-3) for Th(HFAA)4 and (3.8 +/- 0.4) x 10(-3) min-1 for Th(DBM)4, (T = 92 degrees C, I = 3 W cm-2).	beta-diketonate	42-57	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
11013013-2	2000	Our earlier immunohistochemical studies have shown that the deposition of the membrane attack complex (MAC) of complement is associated with the loss of protectin (CD59), a glycosyl-phosphatidylinositol (GPI)-anchored sarcolemmal regulator of MAC, from the human and rat infarcted myocardium.	Glycosylphosphatidylinositols	173-202	CD59 molecule (CD59 blood group)	Homo sapiens	164-168
11045481-4	2000	The isocyanate derivatives were loaded at 10 degrees C and eluted by a three-step temperature program starting at 10 degrees C for 10 min, followed by a temperature ramp of 2.5 degrees C min(-1) to 45 degrees C and then 9.9 degrees C min(-1) to 90 degrees C. The mobile phase consisted of acetonitrile-acetate buffer (3% triethylamine, pH 4.5) (45:55, v/v).	Isocyanates	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	187-193
11045481-4	2000	The isocyanate derivatives were loaded at 10 degrees C and eluted by a three-step temperature program starting at 10 degrees C for 10 min, followed by a temperature ramp of 2.5 degrees C min(-1) to 45 degrees C and then 9.9 degrees C min(-1) to 90 degrees C. The mobile phase consisted of acetonitrile-acetate buffer (3% triethylamine, pH 4.5) (45:55, v/v).	Isocyanates	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	234-240
18968076-3	2000	Optimization by the univariate method was carried out and the optimum conditions for current density, flow rate, sample size and concentration of sulfuric acid were 4 mA, 0.93 ml min(-1), 140 mul and 0.25 M, respectively.	sulfuric acid	146-159	CD59 molecule (CD59 blood group)	Homo sapiens	179-185
11714010-8	2000	However, there was a statistically significant difference in the mean creatinine clearance of the control group 102 ml/min/1.73 m2 when compared with the patient"s mean pre-treatment value (89 ml/min/1.73 m2) P < 0.05.	Creatinine	70-80	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
11714010-9	2000	Also the mean creatinine clearance increased to (103 ml/min/1.73 m2) by the end of the 6th month of treatment, a value that is statistically significant when compared with the pretreatment value of (89 ml/min/1.73 m2) P < 0.05.	Creatinine	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
11714010-9	2000	Also the mean creatinine clearance increased to (103 ml/min/1.73 m2) by the end of the 6th month of treatment, a value that is statistically significant when compared with the pretreatment value of (89 ml/min/1.73 m2) P < 0.05.	Creatinine	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
11014410-3	2000	The area under the concentration versus time curve (AUC) after administration of sustained-release verapamil was 48,951 +/- 18,079 ng/mL x min(-1) in women compared with 25,595 +/- 10,245 in men and lower than after administration of regular-release verapamil (63,055 +/- 24,411 for women and 34,686 +/- 25,279 in men; P = .05 for sex-related effect and P < .02 for formulation effect).	Verapamil	99-108	CD59 molecule (CD59 blood group)	Homo sapiens	139-145
10947750-2	2000	We compared the efficacy and safety of a remifentanil (0.25 microg x kg(-1) x min(-1)-based balanced anaesthetic technique with a bupivacaine-based regional anaesthetic technique in an open label, multicentre study in 271 ASA physical status 1 or 2 children aged 1-12 years.	Remifentanil	41-53	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
10960383-5	2000	min(-1) propofol infusion in combination with 66% nitrous oxide in oxygen for maintenance of anesthesia.	Propofol	8-16	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
10998766-9	2000	Peak oxygen uptake increased from baseline significantly during the first 6 months (from 29.6 +/- 5.7 to 30.6 +/- 6.3 ml.min-1.kg-1) and decreased to the baseline level (29.1 +/- 5.5 ml.min-1.kg-1) at 24 months.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
10998766-9	2000	Peak oxygen uptake increased from baseline significantly during the first 6 months (from 29.6 +/- 5.7 to 30.6 +/- 6.3 ml.min-1.kg-1) and decreased to the baseline level (29.1 +/- 5.5 ml.min-1.kg-1) at 24 months.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
11125761-6	2000	RESULTS: Body mass-normalised maximal oxygen uptake of 58.0+/-4.9 ml x kg(-1) x min(-1) of the group is comparable to values reported in the literature for team game players.	Oxygen	38-44	CD59 molecule (CD59 blood group)	Homo sapiens	80-86
10972692-6	2000	RESULTS: Adjusted creatinine clearance was higher in current smokers than in former smokers and never smokers (100.6 +/- 13.6 vs. 98.8 +/- 13.9 mL/min/1.73 m2, P < 0.0001, and vs. 98.5 +/- 14.0 mL/min/1.	Creatinine	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
10972692-6	2000	RESULTS: Adjusted creatinine clearance was higher in current smokers than in former smokers and never smokers (100.6 +/- 13.6 vs. 98.8 +/- 13.9 mL/min/1.73 m2, P < 0.0001, and vs. 98.5 +/- 14.0 mL/min/1.	Creatinine	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
10972692-10	2000	Creatinine clearance was associated with a relative risk of proteinuria [for each mL/min/1.73 m2, the relative risk was 1.007 (95% CI, 1.000 to 1.015), P = 0.056, for 1+ or higher proteinuria; and 1.018 (1.004 to 1.030), P = 0.0078, for 2+ or higher proteinuria].	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
10937515-7	2000	During the hyperglycemic clamps, glucose and insulin values were similar in both groups before and after therapy However, there was a significant difference in the change in insulin sensitivity in response to treatment between the placebo and the acarbose groups (0.001 +/- 0.001 vs. 0.004 +/- 0.001 mg/kg x min(-1) [pmol/l](-1), respectively, P < 0.05) CONCLUSIONS: Acarbose increases insulin sensitivity but not insulin release in elderly patients with diabetes.	Acarbose	247-255	CD59 molecule (CD59 blood group)	Homo sapiens	308-314
10910490-11	2000	min-1 in the remifentanil group, which was significantly greater than in the desflurane group.	Remifentanil	13-25	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
10910490-11	2000	min-1 in the remifentanil group, which was significantly greater than in the desflurane group.	Desflurane	77-87	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
10990082-5	2000	RESULTS: High concentrations of glucose decreased the expression of CD59 and CD55 by endothelial cells in a time-dependent and glucose concentration-dependent manner without affecting CD46 expression.	Glucose	32-39	CD59 molecule (CD59 blood group)	Homo sapiens	68-72
10990082-6	2000	High concentrations of soluble CD59 were found in the supernatants of cells treated with high glucose.	Glucose	94-101	CD59 molecule (CD59 blood group)	Homo sapiens	31-35
10990082-7	2000	The decrease in CD59 expression induced by high glucose concentrations was reversed by coincubation of cells with a calcium channel blocking agent (Verapamil).	Glucose	48-55	CD59 molecule (CD59 blood group)	Homo sapiens	16-20
10990082-7	2000	The decrease in CD59 expression induced by high glucose concentrations was reversed by coincubation of cells with a calcium channel blocking agent (Verapamil).	Verapamil	148-157	CD59 molecule (CD59 blood group)	Homo sapiens	16-20
10990082-10	2000	CONCLUSION/INTERPRETATION: We speculate that hyperglycaemia could directly contribute to a loss of CD59 and CD55 molecules through a calcium-dependent phosphoinositol-specific phospholipase C activation and subsequent regulation of cell wall expression of GPI-anchored proteins.	Calcium	133-140	CD59 molecule (CD59 blood group)	Homo sapiens	99-103
10990082-10	2000	CONCLUSION/INTERPRETATION: We speculate that hyperglycaemia could directly contribute to a loss of CD59 and CD55 molecules through a calcium-dependent phosphoinositol-specific phospholipase C activation and subsequent regulation of cell wall expression of GPI-anchored proteins.	phosphoinositol	151-166	CD59 molecule (CD59 blood group)	Homo sapiens	99-103
10936797-8	2000	Effective in vivo urea mass transfer coefficient averaged 912 +/- 235 mL/min/1.73 m2, a value close to those reported with more invasive methods.	Urea	18-22	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
10940743-13	2000	During dialysis the clearances of iohexol and iodixanol were, respectively, 69 +/- 16 and 58 +/- 11 ml/min/1.73 m(2) when calculated from a single-pool model (hemodialysis clearance of CM from plasma).	Iohexol	34-41	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
10940743-13	2000	During dialysis the clearances of iohexol and iodixanol were, respectively, 69 +/- 16 and 58 +/- 11 ml/min/1.73 m(2) when calculated from a single-pool model (hemodialysis clearance of CM from plasma).	iodixanol	46-55	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
10955752-12	2000	Evening peak flows were significantly higher during terbutaline treatment [mean increase 23.1 l min(-1) (95% CI = 18.8, 27.4)].	Terbutaline	52-63	CD59 molecule (CD59 blood group)	Homo sapiens	96-102
10955752-15	2000	On ceasing terbutaline treatment there was a fall in mean morning peak flow below the baseline on the following morning of 21.6 l min(-1) (P<0.05 compared to placebo).	Terbutaline	11-22	CD59 molecule (CD59 blood group)	Homo sapiens	130-136
10958374-4	2000	The subjects" oxygen consumption values ranged from 0.14 to 1.19 l x min(-1).	Oxygen	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	69-75
10930971-9	2000	CONCLUSIONS: Adenosine infusion at < or = 140 microg kg-1 min-1 was concluded to be generally well tolerated.	Adenosine	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
10933104-4	2000	The ASTA Medica multi-dose dry powder inhaler (AM-MDPI) has been designed to offer low resistance on inhalation, so that asthmatic patients can achieve inhaled flow rates of approximately 90 L x min(-1).	Cyclophosphamide	4-8	CD59 molecule (CD59 blood group)	Homo sapiens	195-201
10933104-4	2000	The ASTA Medica multi-dose dry powder inhaler (AM-MDPI) has been designed to offer low resistance on inhalation, so that asthmatic patients can achieve inhaled flow rates of approximately 90 L x min(-1).	am-mdpi	47-54	CD59 molecule (CD59 blood group)	Homo sapiens	195-201
10933104-8	2000	At high flow rate (peak inspiratory flow rate 99 L x min(-1)) the AM-MDPI delivered significantly more drug to the lung (median 32.1% of metered dose) than at 65 L x min(-1) or 54 L x min(-1) (median 25.0% and 19.9% of metered dose, respectively), thus demonstrating flow rate dependence.	am-mdpi	66-73	CD59 molecule (CD59 blood group)	Homo sapiens	53-59
10909729-1	2000	The degradation follows first-order kinetics in the initial state with rates in the range 4.5-6.6 microM min-1 under air and 6.0-7.2 microM min-1 under argon at a concentration of 100 microM of chlorophenols.	Argon	152-157	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
10965226-3	2000	Magnesium sulphate infusion (0.05, 0.1, 0.2 mmol x min(-1)) increased plasma Mg(2+) concentration to 1.57+/-0.16 mmol x l(-1) in venous blood from the infused arm at the highest dose.	Magnesium Sulfate	0-18	CD59 molecule (CD59 blood group)	Homo sapiens	51-57
10965226-3	2000	Magnesium sulphate infusion (0.05, 0.1, 0.2 mmol x min(-1)) increased plasma Mg(2+) concentration to 1.57+/-0.16 mmol x l(-1) in venous blood from the infused arm at the highest dose.	magnesium ion	77-83	CD59 molecule (CD59 blood group)	Homo sapiens	51-57
10912897-4	2000	RESULTS: Peak expiratory flow increased from 601 +/- 67 L x min(-1) to 629 +/- 64 L x min(-1) after salbutamol (P < 0.05).	Albuterol	100-110	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
10909729-1	2000	The degradation follows first-order kinetics in the initial state with rates in the range 4.5-6.6 microM min-1 under air and 6.0-7.2 microM min-1 under argon at a concentration of 100 microM of chlorophenols.	Chlorophenols	194-207	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
10858177-9	2000	Carbon monoxide diffusing capacity also decreased in these patients (mean difference, -3.3 x mmol min(-1) x kPa(-1) [Cl, -4.6 to -2.1 mmol x min(-1) x kPa(-1)] and -9.6% of the predicted value [Cl, -16.7% to -2.4%]).	Carbon Monoxide	0-15	CD59 molecule (CD59 blood group)	Homo sapiens	98-104
10858177-9	2000	Carbon monoxide diffusing capacity also decreased in these patients (mean difference, -3.3 x mmol min(-1) x kPa(-1) [Cl, -4.6 to -2.1 mmol x min(-1) x kPa(-1)] and -9.6% of the predicted value [Cl, -16.7% to -2.4%]).	Carbon Monoxide	0-15	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
18967986-6	2000	Detection limits for sulfonic acids in LC with 4.6-mm ID columns (1 ml min(-1) flow rate) were 3 ng.	Sulfonic Acids	21-35	CD59 molecule (CD59 blood group)	Homo sapiens	71-77
10860971-4	2000	The results were further confirmed by using a mAb PAR 15 raised against phenyl-alpha-hydroxyphosphinate Hb, which catalyzes the hydrolysis of PhX (1b), a less toxic phenylphosphonothioate analog of VX with a rate constant of 0.36 M(-1) x min(-1) at pH 7.4 and 25 degrees C, which corresponds to a catalytic proficiency of 14,400 M(-1) toward the rate constant for the uncatalyzed hydrolysis of 1b.	phenyl-alpha-hydroxyphosphinate	72-103	CD59 molecule (CD59 blood group)	Homo sapiens	238-244
10965376-6	2000	Measurements of maximal oxygen uptake before the start of the training (15 mL min-1 kg-1) revealed a level close to the presumed limit for independent living (13 mL min-1 kg-1).	Oxygen	24-30	CD59 molecule (CD59 blood group)	Homo sapiens	78-88
10817690-7	2000	Clearance (CL) of gentamicin C(1), 4.62+/-0.71 ml min(-1) kg(-1), was significantly higher (P = 0.0156) than CL of gentamicin C(1a), 1.81+/-0.26 ml min(-1) kg(-1), and C(2), 1.82+/-0.25 ml min(-1) kg(-1).	gentamicin C	18-30	CD59 molecule (CD59 blood group)	Homo sapiens	50-56
10817690-7	2000	Clearance (CL) of gentamicin C(1), 4.62+/-0.71 ml min(-1) kg(-1), was significantly higher (P = 0.0156) than CL of gentamicin C(1a), 1.81+/-0.26 ml min(-1) kg(-1), and C(2), 1.82+/-0.25 ml min(-1) kg(-1).	gentamicin C	18-30	CD59 molecule (CD59 blood group)	Homo sapiens	148-154
10817690-7	2000	Clearance (CL) of gentamicin C(1), 4.62+/-0.71 ml min(-1) kg(-1), was significantly higher (P = 0.0156) than CL of gentamicin C(1a), 1.81+/-0.26 ml min(-1) kg(-1), and C(2), 1.82+/-0.25 ml min(-1) kg(-1).	gentamicin C	18-30	CD59 molecule (CD59 blood group)	Homo sapiens	148-154
10817690-7	2000	Clearance (CL) of gentamicin C(1), 4.62+/-0.71 ml min(-1) kg(-1), was significantly higher (P = 0.0156) than CL of gentamicin C(1a), 1.81+/-0.26 ml min(-1) kg(-1), and C(2), 1.82+/-0.25 ml min(-1) kg(-1).	Carbon	0-1	CD59 molecule (CD59 blood group)	Homo sapiens	50-56
10817690-7	2000	Clearance (CL) of gentamicin C(1), 4.62+/-0.71 ml min(-1) kg(-1), was significantly higher (P = 0.0156) than CL of gentamicin C(1a), 1.81+/-0.26 ml min(-1) kg(-1), and C(2), 1.82+/-0.25 ml min(-1) kg(-1).	Carbon	0-1	CD59 molecule (CD59 blood group)	Homo sapiens	148-154
10817690-7	2000	Clearance (CL) of gentamicin C(1), 4.62+/-0.71 ml min(-1) kg(-1), was significantly higher (P = 0.0156) than CL of gentamicin C(1a), 1.81+/-0.26 ml min(-1) kg(-1), and C(2), 1.82+/-0.25 ml min(-1) kg(-1).	Carbon	0-1	CD59 molecule (CD59 blood group)	Homo sapiens	148-154
10895752-5	2000	Hydroxyethylstarch was infused in two stages while maintaining mean arterial pressure, allowing a reduction in norepinephrine dose from 0.54 to 0.33 to 0.21 microgram kg-1 min-1.	hydroxyethylstarch	0-18	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
10895752-5	2000	Hydroxyethylstarch was infused in two stages while maintaining mean arterial pressure, allowing a reduction in norepinephrine dose from 0.54 to 0.33 to 0.21 microgram kg-1 min-1.	Norepinephrine	111-125	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
10950945-1	2000	To detect a small population of blood cells with a deficiency of glycosyl phosphatidylinositol (GPI)-anchored protein, we evaluated the expression of CD59 by flow cytometry on one million erythrocytes, which is about 100 times more than the number of erythrocytes tested by our standard immunoassay.	Glycosylphosphatidylinositols	96-99	CD59 molecule (CD59 blood group)	Homo sapiens	150-154
10950945-8	2000	The CD59 assay used in this study is easy to perform and enabled us to detect less than 1% GPI-deficient cells.	Glycosylphosphatidylinositols	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	4-8
10814606-7	2000	During high-dose ATP infusion (75 microg.min(-1).kg(-1)), glucose turnover was 0.62+/-0.07 mmol.h(-1).kg(-1), compared with 0.	Adenosine Triphosphate	17-20	CD59 molecule (CD59 blood group)	Homo sapiens	41-47
10909729-1	2000	The degradation follows first-order kinetics in the initial state with rates in the range 4.5-6.6 microM min-1 under air and 6.0-7.2 microM min-1 under argon at a concentration of 100 microM of chlorophenols.	Chlorophenols	194-207	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
10909729-2	2000	The rate of OH radical formation from water is 19.8 microM min-1 under argon and 14.7 microM min-1 under air in the same sonolysis conditions.	oh radical	12-22	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
10909729-2	2000	The rate of OH radical formation from water is 19.8 microM min-1 under argon and 14.7 microM min-1 under air in the same sonolysis conditions.	oh radical	12-22	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
10909729-2	2000	The rate of OH radical formation from water is 19.8 microM min-1 under argon and 14.7 microM min-1 under air in the same sonolysis conditions.	Water	38-43	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
10909729-2	2000	The rate of OH radical formation from water is 19.8 microM min-1 under argon and 14.7 microM min-1 under air in the same sonolysis conditions.	Water	38-43	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
10909729-2	2000	The rate of OH radical formation from water is 19.8 microM min-1 under argon and 14.7 microM min-1 under air in the same sonolysis conditions.	Argon	71-76	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
10875540-14	2000	The renal clearance of the metabolite acetylmesalazine was independent of the observed defecation patterns (300 mL min(-1), P > 0.8), stool composition, and type of absorption.	N-acetyl-5-aminosalicylic acid	38-54	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
10831203-5	2000	Remifentanil was infused at 0.05 to 0.1 microg x kg(-1) x min(-1) with good sedation and analgesia for the placement of invasive monitors.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
10825749-6	2000	The 55 MeV protons and 32 MeV/nucleon nitrogen ions were each about 10 times more mutagenic per unit dose at the CD59 locus in A(L)C cells than in A(L) cells.	Nitrogen	38-46	CD59 molecule (CD59 blood group)	Homo sapiens	113-117
10801333-1	2000	Formation of the membrane attack complex (MAC) of complement on host cells is inhibited by the glycosylphosphatidylinositol- (GPI-) anchored glycoprotein CD59.	Glycosylphosphatidylinositols	95-123	CD59 molecule (CD59 blood group)	Homo sapiens	154-158
10844831-3	2000	Cardiac output and systemic oxygen consumption increased from 2.83 (0.68) litres min-1 m-2 to 3.17 (0.57) litres min-1 m-2 and from 126 (18) ml min-1 m-2 to 135 (44) ml min-1 m-2, respectively (mean (SD), P = 0.028 and P = 0.019, respectively, baseline vs 6 h).	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
10844831-3	2000	Cardiac output and systemic oxygen consumption increased from 2.83 (0.68) litres min-1 m-2 to 3.17 (0.57) litres min-1 m-2 and from 126 (18) ml min-1 m-2 to 135 (44) ml min-1 m-2, respectively (mean (SD), P = 0.028 and P = 0.019, respectively, baseline vs 6 h).	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
10844831-3	2000	Cardiac output and systemic oxygen consumption increased from 2.83 (0.68) litres min-1 m-2 to 3.17 (0.57) litres min-1 m-2 and from 126 (18) ml min-1 m-2 to 135 (44) ml min-1 m-2, respectively (mean (SD), P = 0.028 and P = 0.019, respectively, baseline vs 6 h).	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
10844831-3	2000	Cardiac output and systemic oxygen consumption increased from 2.83 (0.68) litres min-1 m-2 to 3.17 (0.57) litres min-1 m-2 and from 126 (18) ml min-1 m-2 to 135 (44) ml min-1 m-2, respectively (mean (SD), P = 0.028 and P = 0.019, respectively, baseline vs 6 h).	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
10844834-9	2000	The mean rocuronium infusion rate required to maintain T1/T0 at 15% throughout the procedure was 4.1 micrograms kg-1 min-1.	Rocuronium	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
10817412-9	2000	For the 4 lifts, values (mean +/- SD) varied from 20.3 +/- 5.4 to 28.8 +/- 5.8 mL x kg x min(-1) for oxygen uptake, 42.2 +/- 11.1 to 66.4 +/- 15.2 L x min(-2) for minute ventilation,129 +/- 20.6 to 156 +/- 16.5 beats x min(-1) for heart rate, 5.8 +/- 1.6 to 8.2 +/- 1.6 for metabolic equivalent, and 197 +/- 49.4 to 245 +/- 41.2 for rate-pressure product (x10(-2)).	Oxygen	101-107	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
10795782-1	2000	PURPOSE: The majority of highly trained endurance athletes with a maximal oxygen uptake greater than 60 mL x min(-1) x kg(-1) develop exercise-induced hypoxemia (EIH).	Oxygen	74-80	CD59 molecule (CD59 blood group)	Homo sapiens	109-115
10792012-0	2000	Vanillin (3-methoxy-4-hydroxybenzaldehyde) inhibits mutation induced by hydrogen peroxide, N-methyl-N-nitrosoguanidine and mitomycin C but not (137)Cs gamma-radiation at the CD59 locus in human-hamster hybrid A(L) cells.	vanillin	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	174-178
10792012-1	2000	We have investigated the ability of the naturally occurring plant essence vanillin (3-methoxy-4-hydroxybenzaldehyde) to inhibit mutation at the CD59 locus on human chromosome 11 by hydrogen peroxide, N-methyl-N-nitrosoguanidine, mitomycin C and (137)Cs gamma-radiation in human-hamster hybrid A(L) cells.	vanillin	74-82	CD59 molecule (CD59 blood group)	Homo sapiens	144-148
10792012-1	2000	We have investigated the ability of the naturally occurring plant essence vanillin (3-methoxy-4-hydroxybenzaldehyde) to inhibit mutation at the CD59 locus on human chromosome 11 by hydrogen peroxide, N-methyl-N-nitrosoguanidine, mitomycin C and (137)Cs gamma-radiation in human-hamster hybrid A(L) cells.	vanillin	84-115	CD59 molecule (CD59 blood group)	Homo sapiens	144-148
10792012-8	2000	These results show that vanillin is able to inhibit mutation at the CD59 locus and modify toxicity in a mutagen-specific manner.	vanillin	24-32	CD59 molecule (CD59 blood group)	Homo sapiens	68-72
10753836-10	2000	In addition, PRV-1 contains 2 cysteine-rich domains homologous to those found in the uPAR/Ly6/CD59/snake toxin-receptor superfamily.	Cysteine	30-38	CD59 molecule (CD59 blood group)	Homo sapiens	94-98
10759582-7	2000	The maximal oxygen uptake of skeletal muscle is around 300-400 mL min-1 kg-1.	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	66-76
10759582-8	2000	This uptake rate corresponds to a TCA cycle rate of 4-5 mmol min-1 kg-1, which is of the same magnitude as the activity of oxyglutarate dehydrogenase and pyruvate dehydrogenase, suggesting that these enzymes may be rate limiting for oxygen uptake when an isolated muscle is exercising.	Trichloroacetic Acid	34-37	CD59 molecule (CD59 blood group)	Homo sapiens	61-71
10759582-8	2000	This uptake rate corresponds to a TCA cycle rate of 4-5 mmol min-1 kg-1, which is of the same magnitude as the activity of oxyglutarate dehydrogenase and pyruvate dehydrogenase, suggesting that these enzymes may be rate limiting for oxygen uptake when an isolated muscle is exercising.	Oxygen	233-239	CD59 molecule (CD59 blood group)	Homo sapiens	61-71
10754618-6	2000	The mean arterial blood clearance of clevidipine was 0.069l/kg-1/min-1 and the mean volume of distribution at steady state was 0.19 l/kg.	clevidipine	37-48	CD59 molecule (CD59 blood group)	Homo sapiens	60-70
10711978-4	2000	Mean values for the directly measured oxygen uptake ranged for all trials from 0.5 to 2.1 l O2 min(-1), and analysis of variance showed significant differences regarding slope, load carried, and symmetry.	Oxygen	38-44	CD59 molecule (CD59 blood group)	Homo sapiens	95-101
10711978-5	2000	The calculated values of oxygen uptake based on the biomechanical model correlated significantly with the directly measured values, fitting to the line Y = 0.990 X + 0.144, where Y is the estimated and X is the measured oxygen uptake in l min(-1).	Oxygen	25-31	CD59 molecule (CD59 blood group)	Homo sapiens	239-245
10711978-5	2000	The calculated values of oxygen uptake based on the biomechanical model correlated significantly with the directly measured values, fitting to the line Y = 0.990 X + 0.144, where Y is the estimated and X is the measured oxygen uptake in l min(-1).	Oxygen	220-226	CD59 molecule (CD59 blood group)	Homo sapiens	239-245
10760796-3	2000	We show here that the glycosylphosphatidylinositol linked CD59 molecule is expressed at the surface of Jurkat and J.RT3.T3.5 cells, and when cross-linked by specific antibodies can induce cell death.	Glycosylphosphatidylinositols	22-50	CD59 molecule (CD59 blood group)	Homo sapiens	58-62
10780761-7	2000	The median PV20 3 h post first dose was 69.1 L x min-1 for zafirlukast 80 mg compared to 40 L x min-1 for placebo (p=0.004).	zafirlukast	59-70	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
10780761-8	2000	The corresponding median value for zafirlukast 20 mg was 59.9 L x min-1 (p=0.06).	zafirlukast	35-46	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
10834350-12	2000	During climbing, VO2avg and HRavg means were 1660 +/- 340 ml x min(-1) and 148 +/- 16 b x min(-1) respectively with mean peaks of 2147 +/- 413 ml x min(-1) and 162 +/- 17 b x min(-1).	hravg	28-33	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
10834350-12	2000	During climbing, VO2avg and HRavg means were 1660 +/- 340 ml x min(-1) and 148 +/- 16 b x min(-1) respectively with mean peaks of 2147 +/- 413 ml x min(-1) and 162 +/- 17 b x min(-1).	hravg	28-33	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
10834350-12	2000	During climbing, VO2avg and HRavg means were 1660 +/- 340 ml x min(-1) and 148 +/- 16 b x min(-1) respectively with mean peaks of 2147 +/- 413 ml x min(-1) and 162 +/- 17 b x min(-1).	hravg	28-33	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
10834350-12	2000	During climbing, VO2avg and HRavg means were 1660 +/- 340 ml x min(-1) and 148 +/- 16 b x min(-1) respectively with mean peaks of 2147 +/- 413 ml x min(-1) and 162 +/- 17 b x min(-1).	hravg	28-33	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
10834350-13	2000	Relative VO2avg was 24.7 +/- 4.3 ml x kg(-1) x min(-1) with a mean peak value of 31.9 +/- 5.3 ml x kg(-1) x min(-1).	vo2avg	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	47-53
10708443-2	2000	These domains can be viewed as floating rafts composed of sphingolipids and cholesterol which sequester glycosylphosphatidylinositol (GPI)-linked proteins, such as Thy-1 and CD59.	Sphingolipids	58-71	CD59 molecule (CD59 blood group)	Homo sapiens	174-178
10708443-2	2000	These domains can be viewed as floating rafts composed of sphingolipids and cholesterol which sequester glycosylphosphatidylinositol (GPI)-linked proteins, such as Thy-1 and CD59.	Cholesterol	76-87	CD59 molecule (CD59 blood group)	Homo sapiens	174-178
10708443-2	2000	These domains can be viewed as floating rafts composed of sphingolipids and cholesterol which sequester glycosylphosphatidylinositol (GPI)-linked proteins, such as Thy-1 and CD59.	Glycosylphosphatidylinositols	104-132	CD59 molecule (CD59 blood group)	Homo sapiens	174-178
10708443-2	2000	These domains can be viewed as floating rafts composed of sphingolipids and cholesterol which sequester glycosylphosphatidylinositol (GPI)-linked proteins, such as Thy-1 and CD59.	Glycosylphosphatidylinositols	134-137	CD59 molecule (CD59 blood group)	Homo sapiens	174-178
10760098-5	2000	RESULTS: Transport rates at 10 micromol/L PAH were 21.9 +/- 1.9 and 1.6 +/- 0.4 pmol x mg protein-1 x min-1 (means +/- SEM, N = 10) with membrane vesicles from HEK-MRP2 and HEK-Co cells, respectively.	p-Aminohippuric Acid	42-45	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
10793523-4	2000	If the potassium concentration is 60 mEq.l-1, the estimated safe transfusion rate would be 6 ml.min-1 and this can not be agreed with by clinicians who transfuse daily in cases of massive bleeding.	Potassium	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
10793523-5	2000	The calculated safe transfusion rate (10 mEq.hr-1 of potassium load) ranges from 6 to 72 ml.min-1 considering the storage period from the day of gathering and irradiation.	Potassium	53-62	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
10817395-8	2000	In the postnuclear fraction of human liver homogenate, apparent Km and Vmax for the cleavage of choloyl-CoA were 7.7 x 10-5 mol/L and 3.6 nmol x mg-1 x min-1 respectively.	Choloyl-CoA	96-107	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
10817395-9	2000	The corresponding values for chenodeoxycholoyl-CoA cleavage were 7.1 x 10-5 mol/L and 4.8 nmol x mg-1 x min-1.	Chenodeoxycholoyl-CoA	29-50	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
10704792-10	2000	All ternary mixtures containing 2.5% FL consistently produced a significantly higher (ANOVA P<0.01) fine particle fraction (FPF, 3.1--6.1%) and fine particle dose (FPD, 13.6--30.1 microg) of BDP than the binary mixtures (FPF, 0.3-0.4%; FPD, 1.6-2.1 microg) after aerosolization at 60 l min(-1) via a Rotahaler into a twin stage liquid impinger.	fl	37-39	CD59 molecule (CD59 blood group)	Homo sapiens	289-295
11543272-6	2000	The enzyme operates with multiple turnover in the presence of micromolar concentrations of Zn2+, exhibiting saturation kinetics and a catalytic rate of >1 min-1.	Zinc	91-95	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
18967890-4	2000	A flow-rate of 0.9 ml min(-1) with a water fraction of 0.64 in the ACN-water mixture and a column temperature of 10 degrees C gave the most efficient separation conditions.	Water	37-42	CD59 molecule (CD59 blood group)	Homo sapiens	22-28
10871784-3	2000	We show here that antibodies against two complement regulatory molecules expressed in the membrane of human cells (CD46 and CD59) are present in sera from relapsing-remitting MS patients in the acute phase, that they are directed against the active site of the RCA molecules and that they inactivate their regulatory function, thus providing a mechanism by which cells of the nervous system might be damaged in a complement-dependent fashion during the acute MS phase.	RCA II	261-264	CD59 molecule (CD59 blood group)	Homo sapiens	124-128
18967890-4	2000	A flow-rate of 0.9 ml min(-1) with a water fraction of 0.64 in the ACN-water mixture and a column temperature of 10 degrees C gave the most efficient separation conditions.	3-hydroxy-5-estrane-17-carbonitrile	67-70	CD59 molecule (CD59 blood group)	Homo sapiens	22-28
10777026-5	2000	During isradipine administration, blood pressure decreased from 151 +/- 3/91 +/- 2 to 130 +/-3/81 +/- 2 mm Hg (P < .01) without change in renal blood flow (406 +/- 43 to 425 +/- 52 mL/min/1.73m2, P = NS) or renal vascular resistance index (25,674 +/-3312 to 20,520 +/- 2311 dynes x sec x cm(-5)/m2, P = NS).	Isradipine	7-17	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
10712321-6	2000	Then dopexamine infusion was titrated (1-4 microg x kg(-1) x min(-1)) to increase cardiac output by approximately 25% (20-30%).	dopexamine	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	61-68
10719950-4	2000	METHODS: In 18 patients, mivacurium was infused at 10 microg kg(-1) x min(-1) for 40 min, the infusion was discontinued for 15 min and then restarted at the same rate for another 40 min.	Mivacurium	25-35	CD59 molecule (CD59 blood group)	Homo sapiens	70-76
10718776-2	2000	METHODS: Risedronate was administered to adult men and women (n=21) with various degrees of renal function (creatinine clearance 15-126 ml min-1 ) as a single oral dose of 30 mg. Serum samples were obtained for 72 h after dosing, and urine samples were collected for 72 h after dosing and then periodically for 6 weeks.	Risedronic Acid	9-20	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
10718776-6	2000	Decreases in predicted renal clearance and volume of distribution of 82 and 69%, respectively, were observed when creatinine clearance decreased from 120 to 20 ml min-1.	Creatinine	114-124	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
10718776-7	2000	A 64% decrease in predicted oral clearance was observed when creatinine clearance decreased from 120 to 20 ml min-1 (P=0.064).	Creatinine	61-71	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
10793594-7	2000	injection (n = 9), the mean elimination half-life of tramadol was 6.4 (SD 2.7) h, with a volume of distribution of 3.1 (1.1) litre kg-1 and total plasma clearance of 6.1 (2.5) ml kg-1 min-1.	Tramadol	53-61	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
10733024-5	2000	RESULTS: The mean superoxide anion production of PMNLs of healthy controls was 1.855 nM/min/3 x 10(5) cells (SD=0.211 nM/min/3 x 10(5) cells).	Superoxides	18-34	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
10784090-4	2000	Simulated impulse responses from the system, analogous to tracer water outflow dilution curves, showed flow-limited behavior over a range of flows from about 2 to 5 ml min(-1) g(-1), as is observed for water in the heart in vivo.	Water	202-207	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
10681485-6	2000	METHODS: Seventy five patients with previous myocardial infarction were studied in a low dose (up to 20 microg(-1) x kg(-1) x min(-1)) dobutamine stress echocardiography study.	Dobutamine	135-145	CD59 molecule (CD59 blood group)	Homo sapiens	126-132
10733024-5	2000	RESULTS: The mean superoxide anion production of PMNLs of healthy controls was 1.855 nM/min/3 x 10(5) cells (SD=0.211 nM/min/3 x 10(5) cells).	Superoxides	18-34	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
10720601-15	2000	min(-1) per 1.73 m(2) during the first norepinephrine infusion, without subsequent change.	Norepinephrine	39-53	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
10691227-10	2000	CONCLUSIONS: A decrease in DO2 to 7.3+/-1.4 ml O2 x kg(-1) min(-1) in resting, healthy, conscious humans does not produce evidence of inadequate systemic oxygenation.	do2	27-30	CD59 molecule (CD59 blood group)	Homo sapiens	59-65
10736099-5	2000	In two patients with active lupus, the percentage of CD59dim CD8+ T cells was significantly decreased after steroid therapy.	Steroids	108-115	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
10662708-8	2000	At rest after training, the percentage of glucose rate of appearance (R(a)) from GNG more than doubled (1.98 +/- 0.5% pretraining; 5.45 +/- 1.3% posttraining), as did the rate of GNG (0.11 +/- 0.03 mg x kg(-1) x min(-1) pretraining, 0.24 +/- 0.06 mg x kg(-1) x min(-1) posttraining).	Glucose	42-49	CD59 molecule (CD59 blood group)	Homo sapiens	212-218
10662708-8	2000	At rest after training, the percentage of glucose rate of appearance (R(a)) from GNG more than doubled (1.98 +/- 0.5% pretraining; 5.45 +/- 1.3% posttraining), as did the rate of GNG (0.11 +/- 0.03 mg x kg(-1) x min(-1) pretraining, 0.24 +/- 0.06 mg x kg(-1) x min(-1) posttraining).	Glucose	42-49	CD59 molecule (CD59 blood group)	Homo sapiens	261-267
10691218-5	2000	After placement of venous and arterial catheters, dopamine was infused at 10 microg x kg(-1) x min(-1) for 10 min, followed by a 30-min washout period.	Dopamine	50-58	CD59 molecule (CD59 blood group)	Homo sapiens	95-101
10691218-6	2000	Subsequently, dopamine was infused at 3 microg x kg(-1) x min(-1) for 90 min, followed by another 30-min washout period.	Dopamine	14-22	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
10691218-9	2000	RESULTS: Plasma concentrations of dopamine varied from 12,300 to 201,500 ng/l after 10 min of dopamine infusion at 10 microg x kg(-1) x min(-1).	Dopamine	34-42	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
10691227-0	2000	Critical oxygen delivery in conscious humans is less than 7.3 ml O2 x kg(-1) x min(-1).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	79-85
10671910-9	2000	In incubations with single formoterol enantiomers, the median (n=9) Km values for (R; R)-glucuronide and (S; S)-glucuronide were 827.6 and 840.4 microm, respectively, and the median V max values were 2625 and 4304 pmol min-1 mg-1, respectively.	Formoterol Fumarate	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	219-229
10671910-10	2000	Corresponding values determined in incubations with rac-formoterol were 357.2 and 312.1 microm and 1435 and 2086 pmol min-1 mg-1 for (R; R)- and (S; S)-glucuronide, respectively.	rac-formoterol	52-66	CD59 molecule (CD59 blood group)	Homo sapiens	118-128
10671910-10	2000	Corresponding values determined in incubations with rac-formoterol were 357.2 and 312.1 microm and 1435 and 2086 pmol min-1 mg-1 for (R; R)- and (S; S)-glucuronide, respectively.	Glucuronides	152-163	CD59 molecule (CD59 blood group)	Homo sapiens	118-128
10755725-7	2000	MBF averaged for all subjects was 0.93+/-0.34 ml min(-1) g(-1) at rest and 3.40+/-1.73 ml min(-1) g(-1) after the administration of dipyridamole, and the flow reserve (defined as the ratio of the two MBF values) was 3.82+/-2.12; these values are consistent with previous reports.	Dipyridamole	132-144	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
10727072-1	2000	Maximal oxygen uptake (VO2max) in females, expressed as ml x kg(-1) x min(-1), declines steadily during the first three decades of life.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	70-76
10709930-6	2000	Lysine uptake occurred by a transport mechanism with a Km of approximately 1.4 mM and a Vmax of 7.9 mmol x kg cell water(-1) x 30 min(-1).	Lysine	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	130-136
10709930-6	2000	Lysine uptake occurred by a transport mechanism with a Km of approximately 1.4 mM and a Vmax of 7.9 mmol x kg cell water(-1) x 30 min(-1).	Water	115-120	CD59 molecule (CD59 blood group)	Homo sapiens	130-136
10657833-6	2000	The mean creatinine clearance increased from 90 +/- 23 to 107 +/- 23 mL/min/1.73 mol/L(2) (P <.01), and the mean 24-hour urine protein excretion decreased from 2.0 +/- 2.4 g/24 h to 0.5 +/- 0.7 g/24 h (P <.05).	Creatinine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
10714949-8	2000	Vmax for glucuronide formation was more than 4-fold higher in the rat liver compared with human liver preparations (185.9+/-34.5 and 42.6+/-7.1 pmol (mg protein)(-1) min(-1), respectively).	Glucuronides	9-20	CD59 molecule (CD59 blood group)	Homo sapiens	166-172
10786997-4	2000	This gp41 peptide apparently down-regulated phorbol 12,13-dibutyrate induced elevation of CD59 at the protein and mRNA levels in a manner similar to that conferred by protein kinase C inhibitor, H-7 or staurosporine in SK-N-SH.	Phorbol 12,13-Dibutyrate	44-68	CD59 molecule (CD59 blood group)	Homo sapiens	90-94
11227721-5	2000	After the individualized training programme, peak oxygen consumption on exercise (1679 +/- 100 vs 1487 +/- 89 ml.min-1, p = 0.0001) and at ventilatory threshold increased (1365 +/- 85 vs 1133 +/- 65 ml.min-1, p = 0.0001), the ventilatory threshold/peak exercise ratio increased (81.2 +/- 1.3 vs 76.7 +/- 1.4%, p = 0.0008), and there was a decrease in heart and ventilatory rates at submaximal metabolic levels (p = 0.0001).	Oxygen	50-56	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
10740546-5	2000	After 120 min, the cumulative infusion rate of rocuronium to obtain twitch depression of 90-95% was 9.0 (1.9), 6.3 (1.6), 6.1 (2.0) and 6.1 (1.1) micrograms kg-1 min-1 during propofol, isoflurane, sevoflurane and desflurane anaesthesia, respectively (P < 0.01).	Rocuronium	47-57	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
10740557-3	2000	followed by a bolus dose of remifentanil 1 microgram kg-1 over 30 s and an infusion of remifentanil at a rate of 0.5 microgram kg-1 min-1.	Remifentanil	87-99	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
10771452-8	2000	The apparent Km and Vmax values for the formation of the major metabolite, ziprasidone sulphoxide (measured as the sum of sulphoxide and sulphone) were 235 microM and 1.14 nmol mg(-1) protein min(-1), respectively.	Ziprasidone Sulfoxide	75-97	CD59 molecule (CD59 blood group)	Homo sapiens	192-198
10771452-8	2000	The apparent Km and Vmax values for the formation of the major metabolite, ziprasidone sulphoxide (measured as the sum of sulphoxide and sulphone) were 235 microM and 1.14 nmol mg(-1) protein min(-1), respectively.	sulfoxide	87-97	CD59 molecule (CD59 blood group)	Homo sapiens	192-198
10651786-8	2000	After baseline measurements, adrenaline was infused at a rate of 0.3 nmol kg-1 min-1.	Epinephrine	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
10651786-10	2000	During infusion of adrenaline, blood flow and lactate output increased significantly more in the non-dominant arm (8.12 +/- 1.24 versus 6.45 +/- 1.19 ml 100 g-1 min-1) and (2.99 +/- 0.60 versus 1.83 +/- 0.43 micromol 100 g-1 min-1).	Epinephrine	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
10651786-10	2000	During infusion of adrenaline, blood flow and lactate output increased significantly more in the non-dominant arm (8.12 +/- 1.24 versus 6.45 +/- 1.19 ml 100 g-1 min-1) and (2.99 +/- 0.60 versus 1.83 +/- 0.43 micromol 100 g-1 min-1).	Epinephrine	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	225-230
10651786-11	2000	Adrenaline induced a significant increase in oxygen uptake in the non-dominant forearm (baseline period: 4.98 +/- 0.72 micromol 100 g-1 min-1; adrenaline period: 6.63 +/- 0.62 micromol 100 g-1 min-1) while there was no increase in the dominant forearm (baseline period: 5.69 +/- 1.03 micromol 100 g-1 min-1; adrenaline period: 4.	Epinephrine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
10651786-11	2000	Adrenaline induced a significant increase in oxygen uptake in the non-dominant forearm (baseline period: 4.98 +/- 0.72 micromol 100 g-1 min-1; adrenaline period: 6.63 +/- 0.62 micromol 100 g-1 min-1) while there was no increase in the dominant forearm (baseline period: 5.69 +/- 1.03 micromol 100 g-1 min-1; adrenaline period: 4.	Epinephrine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
10651786-11	2000	Adrenaline induced a significant increase in oxygen uptake in the non-dominant forearm (baseline period: 4.98 +/- 0.72 micromol 100 g-1 min-1; adrenaline period: 6.63 +/- 0.62 micromol 100 g-1 min-1) while there was no increase in the dominant forearm (baseline period: 5.69 +/- 1.03 micromol 100 g-1 min-1; adrenaline period: 4.	Epinephrine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
10651786-11	2000	Adrenaline induced a significant increase in oxygen uptake in the non-dominant forearm (baseline period: 4.98 +/- 0.72 micromol 100 g-1 min-1; adrenaline period: 6.63 +/- 0.62 micromol 100 g-1 min-1) while there was no increase in the dominant forearm (baseline period: 5.69 +/- 1.03 micromol 100 g-1 min-1; adrenaline period: 4.	Oxygen	45-51	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
10651786-11	2000	Adrenaline induced a significant increase in oxygen uptake in the non-dominant forearm (baseline period: 4.98 +/- 0.72 micromol 100 g-1 min-1; adrenaline period: 6.63 +/- 0.62 micromol 100 g-1 min-1) while there was no increase in the dominant forearm (baseline period: 5.69 +/- 1.03 micromol 100 g-1 min-1; adrenaline period: 4.	Oxygen	45-51	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
10651786-11	2000	Adrenaline induced a significant increase in oxygen uptake in the non-dominant forearm (baseline period: 4.98 +/- 0.72 micromol 100 g-1 min-1; adrenaline period: 6.63 +/- 0.62 micromol 100 g-1 min-1) while there was no increase in the dominant forearm (baseline period: 5.69 +/- 1.03 micromol 100 g-1 min-1; adrenaline period: 4.	Oxygen	45-51	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
10620007-6	2000	Whole body leucine flux showed a tendency to decrease in the intervention group from 1.92 +/- 0.19 to 1.73 +/- 0.14 micromol kg-1 min-1 (P = 0.07) and remained unchanged in the control group (2.21 +/- 0.16 and 2.27 +/- 0.14 micromol kg-1 min-1, respectively).	Leucine	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
10620007-6	2000	Whole body leucine flux showed a tendency to decrease in the intervention group from 1.92 +/- 0.19 to 1.73 +/- 0.14 micromol kg-1 min-1 (P = 0.07) and remained unchanged in the control group (2.21 +/- 0.16 and 2.27 +/- 0.14 micromol kg-1 min-1, respectively).	Leucine	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
10662901-5	2000	At 120 rev min-1 there was also a pronounced upward shift of the O2-power output (O2-P) relationship.	Oxygen	65-67	CD59 molecule (CD59 blood group)	Homo sapiens	11-16
10662901-5	2000	At 120 rev min-1 there was also a pronounced upward shift of the O2-power output (O2-P) relationship.	Oxygen	82-84	CD59 molecule (CD59 blood group)	Homo sapiens	11-16
10662901-6	2000	At 50 W O2 between 80 and 100 rev min-1 amounted to +0.43 l min-1 but to +0.87 l min-1 between 100 and 120 rev min-1.	Oxygen	8-10	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
10662901-6	2000	At 50 W O2 between 80 and 100 rev min-1 amounted to +0.43 l min-1 but to +0.87 l min-1 between 100 and 120 rev min-1.	Oxygen	8-10	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
10662901-6	2000	At 50 W O2 between 80 and 100 rev min-1 amounted to +0.43 l min-1 but to +0.87 l min-1 between 100 and 120 rev min-1.	Oxygen	8-10	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
10662901-11	2000	However, beyond 100 rev min-1 there is a decrease in external power that can be delivered for an given O2 with an associated earlier onset of metabolic acidosis and clearly this will be disadvantageous for sustained high intensity exercise.	Oxygen	103-105	CD59 molecule (CD59 blood group)	Homo sapiens	24-29
10812612-2	2000	Under these conditions the decay rate of the light emission expressed as percentage per minute is a measure of luciferase activity and can be given as the rate constant k (min-1), directly reflecting the degradation of ATP in the luciferase reaction.	Adenosine Triphosphate	219-222	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
10792741-12	2000	The baseline heart rate increased from 87+/-13 b.min-1 to a maximum of 114+/-16 b.min-1 (P < 0.0001) during the fenoldopam infusion.	Fenoldopam	115-125	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
10691227-10	2000	CONCLUSIONS: A decrease in DO2 to 7.3+/-1.4 ml O2 x kg(-1) min(-1) in resting, healthy, conscious humans does not produce evidence of inadequate systemic oxygenation.	Oxygen	28-30	CD59 molecule (CD59 blood group)	Homo sapiens	59-65
11831986-3	2000	The constructed eukaryorotic expression vectors containing the human CD(59) cDNA, LXSN-CD(59) were identified by the methods of restriction endonucleases cleavage, agarose gel electrophoresis, and polymerase chain reaction.	Sepharose	164-171	CD59 molecule (CD59 blood group)	Homo sapiens	69-75
10593979-3	1999	In purified intact peroxisomes a Ca(2+)-dependent NOS activity of 5.61 nmol of L-[(3)H]citrulline mg(-1) protein min(-1) was measured while no activity was detected in mitochondria.	l-[(3)h]citrulline	79-97	CD59 molecule (CD59 blood group)	Homo sapiens	113-119
10589606-5	1999	We found that patients with high trait anxiety required more propofol for both the induction (2.1+/-0.4 vs 1.8+/-0.3 mg/kg; P = 0.01) and maintenance of anesthesia (170+/-70 vs 110+/-20 microg x kg(-1) x min(-1); P = 0.02), compared with patients with low trait anxiety.	Propofol	61-69	CD59 molecule (CD59 blood group)	Homo sapiens	204-210
10594422-3	1999	Intra-operatively it was noted that patients given rocuronium (20 mg) had significantly fewer episodes of bradycardia (heart rate < 50 beat.min-1) than patients given vecuronium 4 mg (p < 0.05).	Rocuronium	51-61	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
10598598-6	1999	RESULTS: Dobutamine increased cardiac index (3.0+/-0.6 to 4.4+/-1.0 l x min(-1)m(-2), mean +/- SD; P < 0.05), splanchnic blood flow (from 0.8+/-0.2 to 1.0 + 0.2 l x min(-1)m(-2); P < 0.05), femoral blood flow (from 0.2+/-0.1 to 0.3+/-0.1 l x min(-1)m(-2); P < 0.05), and the arterial-gastric mucosal Pco2 gap (from 11.4+/-9.5 to 11.9+/-8.0 mmHg; P < 0.05).	Dobutamine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	72-78
10598598-6	1999	RESULTS: Dobutamine increased cardiac index (3.0+/-0.6 to 4.4+/-1.0 l x min(-1)m(-2), mean +/- SD; P < 0.05), splanchnic blood flow (from 0.8+/-0.2 to 1.0 + 0.2 l x min(-1)m(-2); P < 0.05), femoral blood flow (from 0.2+/-0.1 to 0.3+/-0.1 l x min(-1)m(-2); P < 0.05), and the arterial-gastric mucosal Pco2 gap (from 11.4+/-9.5 to 11.9+/-8.0 mmHg; P < 0.05).	Dobutamine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
10598598-6	1999	RESULTS: Dobutamine increased cardiac index (3.0+/-0.6 to 4.4+/-1.0 l x min(-1)m(-2), mean +/- SD; P < 0.05), splanchnic blood flow (from 0.8+/-0.2 to 1.0 + 0.2 l x min(-1)m(-2); P < 0.05), femoral blood flow (from 0.2+/-0.1 to 0.3+/-0.1 l x min(-1)m(-2); P < 0.05), and the arterial-gastric mucosal Pco2 gap (from 11.4+/-9.5 to 11.9+/-8.0 mmHg; P < 0.05).	Dobutamine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
10598598-7	1999	Dobutamine increased systemic oxygen consumption (from 132+/-14 to 146+/-13 ml x min(-1) x m(-2); P < 0.05) but not splanchnic or femoral oxygen consumption.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
10606886-6	1999	Flow cytometric analysis of the peripheral blood of this patient during remission after cyclosporine therapy revealed 1.7% of granulocytes to be deficient in CD59.	Cyclosporine	88-100	CD59 molecule (CD59 blood group)	Homo sapiens	158-162
10602327-6	1999	Na+-dependent L-glutamate uptake activity (3.2 pmol min-1 mg-1) was observed in EcR 293 cells and this was increased approximately 2 fold in the uninduced HEK/EAAT2 cells, indicating a low level of basal EAAT2 activity in the absence of exogenous inducing agent.	Glutamic Acid	14-25	CD59 molecule (CD59 blood group)	Homo sapiens	52-62
10602327-9	1999	L-glutamate uptake into induced HEK/EAAT2 cells followed first-order Michaelis-Menten kinetics and Eadie-Hofstee transformation of the saturable uptake data produced estimates of kinetic parameters as follows; Km 52.7+/-7.5 microM, Vmax 3.8+/-0.9 nmol min-1 mg-1 protein.	Glutamic Acid	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	252-262
10606236-4	1999	In cells pretreated with BSO for 24 h, the mutation yield at the CD59 locus induced by a 4 microg/cm2 dose of crocidolite fibers was increased by more than 3-fold (P < 0.05).	Asbestos, Crocidolite	110-121	CD59 molecule (CD59 blood group)	Homo sapiens	65-69
10624761-10	1999	However, only the breathlessness score was independently associated with the TL,CO (-0.42 mmol x min(-1) x kPa(-1) per breathlessness score unit) after adjusting for other respiratory symptoms, and the relationship was stronger in males than in females.	Carbon Monoxide	80-84	CD59 molecule (CD59 blood group)	Homo sapiens	97-103
10562352-14	1999	The peripheral chemoreflex sensitivity to CO2 in hypoxia was reduced from 2.42 +/- 0.36 to 1.18 +/- 0.20 l min-1 Torr-1 (P < 0.005) with somatostatin.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	42-45	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
11012955-5	2000	supplementation (20+/-10 microg x kg(-1) x min(-1) S-(+)-ketamine and 4+/-2 microg x kg(-1) x min(-1) midazolam), spontaneous ventilation was maintained.	Sulfur	51-52	CD59 molecule (CD59 blood group)	Homo sapiens	43-49
10572198-2	1999	Conventional DSC indicated that quenched sulfapyridine exhibited a series of transitions on reheating at 10 degrees C min(-1) which were ascribed to a glass transition (56.9 degrees C), cold crystallisation (103.7 degrees C), a solid-solid transition (131.4 degrees C) and metastable and stable polymorphic melting (177.3 and 186.3 degrees C).	Sulfapyridine	41-54	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
10567326-8	1999	The values subsequently remained unchanged in control patients (3.62+/-0.94 nmol x mg protein(-1) x min(-1)), whereas they significantly increased after isoflurane preconditioning (4.74+/-0.	Isoflurane	153-163	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
10540089-6	1999	In these patients the median remifentanil target concentration was 1.6 ng x ml-1 and was achieved with a median infusion rate of 0.05 microg x kg-1 x min-1.	Remifentanil	29-41	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
10551583-3	1999	METHODS: One hundred patients received sequential 3-min infusions of dobutamine at 0-40 microg x kg(-1) x min(-1) immediately after cardiopulmonary bypass.	Dobutamine	69-79	CD59 molecule (CD59 blood group)	Homo sapiens	106-112
10551583-10	1999	Systemic vascular resistance initially increased with dobutamine 10 microg x kg(-1) x min(-1) and remained constant with larger doses.	Dobutamine	54-64	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
10553851-14	1999	In conclusion, the recommended remifentanil infusion rate for controlling acute autonomic responses during neurosurgical anesthesia is 0.125 microg x kg(-1) x min(-1) when administered during a desflurane-based anesthetic.	Remifentanil	31-43	CD59 molecule (CD59 blood group)	Homo sapiens	159-165
10564709-3	1999	The kinetic analysis of L-arginine uptake in the presence of Na+ revealed that the process is mediated by saturable components: a high-affinity system (Km = 167 +/- 18.0 microM; Vmax = 0.174 +/- 0.012 micromol min-1) and a low-affinity carrier (Km = 980 +/- 112 microM; Vmax = 1.60 +/- 0.12 micromol min-1).	Arginine	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	210-215
10552089-8	1999	8+/-0.06 ml min(-1) g(-1) at rest and 1.48+/-0.15 ml min(-1) g(-1) during dobutamine stress.	Dobutamine	74-84	CD59 molecule (CD59 blood group)	Homo sapiens	53-59
10552089-9	1999	Oxygen delivery and consumption were 151+/-13 and 88+/-15 microl O(2) min(-1) g(-1) at rest and increased to 291+/-31 and 216+/-31 microl O(2) min(-1) g(-1), respectively, during pharmacological stress (P<0.001).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	70-76
10552089-9	1999	Oxygen delivery and consumption were 151+/-13 and 88+/-15 microl O(2) min(-1) g(-1) at rest and increased to 291+/-31 and 216+/-31 microl O(2) min(-1) g(-1), respectively, during pharmacological stress (P<0.001).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	143-149
10564709-3	1999	The kinetic analysis of L-arginine uptake in the presence of Na+ revealed that the process is mediated by saturable components: a high-affinity system (Km = 167 +/- 18.0 microM; Vmax = 0.174 +/- 0.012 micromol min-1) and a low-affinity carrier (Km = 980 +/- 112 microM; Vmax = 1.60 +/- 0.12 micromol min-1).	Arginine	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	300-305
10564709-6	1999	Kinetic studies in placentae taken from aspirin-treated pregnancies showed that L-arginine is transported with a significantly higher affinity (Km = 42.5 +/- 5.7 microM), but with a lower capacity (Vmax = 0.064 +/- 0.003 micromol min-1) than in the non-treated group.	Aspirin	40-47	CD59 molecule (CD59 blood group)	Homo sapiens	230-235
10564709-6	1999	Kinetic studies in placentae taken from aspirin-treated pregnancies showed that L-arginine is transported with a significantly higher affinity (Km = 42.5 +/- 5.7 microM), but with a lower capacity (Vmax = 0.064 +/- 0.003 micromol min-1) than in the non-treated group.	Arginine	80-90	CD59 molecule (CD59 blood group)	Homo sapiens	230-235
10566964-4	1999	After correction for partial volume effects using a model with two tissue compartments, the tricarboxylic acid cycle rate in pure grey matter was higher (0.80+/-0.10 mol min(-1) g(-1); mean +/- SD) and in white matter was significantly lower (0.17+/-0.01 micromol min(-1) g(-1); mean +/- SD).	Tricarboxylic Acids	92-110	CD59 molecule (CD59 blood group)	Homo sapiens	170-176
10566964-4	1999	After correction for partial volume effects using a model with two tissue compartments, the tricarboxylic acid cycle rate in pure grey matter was higher (0.80+/-0.10 mol min(-1) g(-1); mean +/- SD) and in white matter was significantly lower (0.17+/-0.01 micromol min(-1) g(-1); mean +/- SD).	Tricarboxylic Acids	92-110	CD59 molecule (CD59 blood group)	Homo sapiens	264-270
10574479-9	1999	RESULTS: The plasma concentration of 3-hydroxybutyrate monomer reached 572 +/- 11 micromol/L 15 minutes after beginning infusion of the mixture at a rate of 25 micromol x kg(-1) x min(-1) and 270 +/- 40 micromol/L at a rate of 12.5 micromol x kg(-1) min(-1).	3-Hydroxybutyric Acid	37-54	CD59 molecule (CD59 blood group)	Homo sapiens	180-186
10674924-4	1999	Administration of 400 microg capsaicin significantly increased the slope of gastric emptying curve (from 0.1 +/- 0.01 to 0.139 +/- 0.014 U x min(-1), P < 0.05) and significantly decreased the time belonging to the maximum value of emptying curve (from 150 +/- 18 to 75 +/- 12 min, P < 0.05) and the time belonging to the 50% of the area under the curve (from 112 +/- 15 to 99 +/- 14 min, P < 0.05).	Capsaicin	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
10574479-9	1999	RESULTS: The plasma concentration of 3-hydroxybutyrate monomer reached 572 +/- 11 micromol/L 15 minutes after beginning infusion of the mixture at a rate of 25 micromol x kg(-1) x min(-1) and 270 +/- 40 micromol/L at a rate of 12.5 micromol x kg(-1) min(-1).	3-Hydroxybutyric Acid	37-54	CD59 molecule (CD59 blood group)	Homo sapiens	250-256
10571018-2	1999	A considerable part of erythrocytes in patient blood is susceptible to autologous complement activation because of the deficiency of CD59, which is a glycosylphosphatidylinositol (GPI)-anchored protein and inhibits the formation of the membrane attack complex (MAC) of complement.	Glycosylphosphatidylinositols	150-178	CD59 molecule (CD59 blood group)	Homo sapiens	133-137
10586561-11	1999	Anesthesia was induced with midazolam 3 mg, sevoflurane 5%, nitrous oxide 8 l.min-1 in oxygen 4 l.min-1.	Oxygen	87-93	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
10586561-11	1999	Anesthesia was induced with midazolam 3 mg, sevoflurane 5%, nitrous oxide 8 l.min-1 in oxygen 4 l.min-1.	Oxygen	87-93	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
10571018-2	1999	A considerable part of erythrocytes in patient blood is susceptible to autologous complement activation because of the deficiency of CD59, which is a glycosylphosphatidylinositol (GPI)-anchored protein and inhibits the formation of the membrane attack complex (MAC) of complement.	Glycosylphosphatidylinositols	180-183	CD59 molecule (CD59 blood group)	Homo sapiens	133-137
10583018-8	1999	The plasma dialysis clearances for R- and S-ketoprofen glucuronides were 49.4+/-19.8 and 39.0+/-15.9 ml min-1, respectively, and 10.8+/-17.6 and 13.3+/-23.5 ml min-1 for unconjugated R- and S-ketoprofen.	r- and s-ketoprofen glucuronides	35-67	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
10512253-4	1999	In patients given clonidine, the mean BP increases induced by DOA 5 microg x kg(-1) x min(-1) were significantly attenuated (P < 0.01), whereas the mean BP increases induced by DOB-0.5, 1, or 3 microg x kg(-l) x min(-1) were significantly enhanced (P < 0.01 or 0.05).	Clonidine	18-27	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
10512253-4	1999	In patients given clonidine, the mean BP increases induced by DOA 5 microg x kg(-1) x min(-1) were significantly attenuated (P < 0.01), whereas the mean BP increases induced by DOB-0.5, 1, or 3 microg x kg(-l) x min(-1) were significantly enhanced (P < 0.01 or 0.05).	Clonidine	18-27	CD59 molecule (CD59 blood group)	Homo sapiens	215-221
10512253-4	1999	In patients given clonidine, the mean BP increases induced by DOA 5 microg x kg(-1) x min(-1) were significantly attenuated (P < 0.01), whereas the mean BP increases induced by DOB-0.5, 1, or 3 microg x kg(-l) x min(-1) were significantly enhanced (P < 0.01 or 0.05).	Dopamine	62-65	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
10519477-9	1999	Administration of dantrolene on the development of heat stroke appeared to improve cooling in the exercise group (0.25 degrees C x min(-1) and 0.18 degrees C x min(-1), for the first 1 5 min of cooling, for E+D1 and EC, respectively).	Dantrolene	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	131-137
10519477-9	1999	Administration of dantrolene on the development of heat stroke appeared to improve cooling in the exercise group (0.25 degrees C x min(-1) and 0.18 degrees C x min(-1), for the first 1 5 min of cooling, for E+D1 and EC, respectively).	Dantrolene	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	160-166
10673885-8	1999	Apnoea occurred in five of 15 patients who did not receive oxygen before sevoflurane and in four of 13 who received oxygen 6 litre min-1 (P < 0.05).	Oxygen	116-122	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
10673885-10	1999	We conclude that inhalation induction of anaesthesia can be performed reliably in approximately 3 min using sevoflurane in oxygen 3 litre min-1.	Sevoflurane	108-119	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
10583018-8	1999	The plasma dialysis clearances for R- and S-ketoprofen glucuronides were 49.4+/-19.8 and 39.0+/-15.9 ml min-1, respectively, and 10.8+/-17.6 and 13.3+/-23.5 ml min-1 for unconjugated R- and S-ketoprofen.	r- and s-ketoprofen	35-54	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
10547215-9	1999	Glucagon infusion was increased to 2.1 ng x kg(-1) x min(-1) at 240-360 min (step 1) and to 4.2 ng x kg(-1) x min(-1) at 360-420 min (step 2).	Glucagon	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	53-59
10547215-9	1999	Glucagon infusion was increased to 2.1 ng x kg(-1) x min(-1) at 240-360 min (step 1) and to 4.2 ng x kg(-1) x min(-1) at 360-420 min (step 2).	Glucagon	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	110-116
18967757-6	1999	In optimized conditions (flow rate of 2.1 ml min(-1) and volume of injection of 150 mul), the tubular electrode showed a linear response to ASA in the concentration range between 4.0x10(-3) and 4.0x10(-2) mol l(-1).	Aspirin	140-143	CD59 molecule (CD59 blood group)	Homo sapiens	45-51
10491184-8	1999	The purified MRP2-(His)6 glycoprotein was reconstituted into proteoliposomes and showed functional activity as ATPase in a protein-dependent manner with a Km for ATP of 2.1 mM and a Vmax of 25 nmol ADP x mg MRP2-1 x min-1.	Adenosine Triphosphate	111-114	CD59 molecule (CD59 blood group)	Homo sapiens	216-221
10656171-6	1999	glucose tolerance factor KG (2.0 +/- 0.2 vs 2.2 +/- 0.1% min-1), SG (0.035 +/- 0.004 vs 0.032 +/- 0.007 min-1) and S1 [3.5 +/- 0.5 vs 3.8 +/- 0.3 10(4) min-1 (microU/mL)] were similar, both basal insulin and C-peptide exhibited a marked increase (87 +/- 8 vs 46 +/- 6 pmol/L, p = 0.0003; 637 +/- 62 vs 381 +/- 76 pmol/L, p < 0.03) demonstrating insulin resistance in basal conditions.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
10656171-6	1999	glucose tolerance factor KG (2.0 +/- 0.2 vs 2.2 +/- 0.1% min-1), SG (0.035 +/- 0.004 vs 0.032 +/- 0.007 min-1) and S1 [3.5 +/- 0.5 vs 3.8 +/- 0.3 10(4) min-1 (microU/mL)] were similar, both basal insulin and C-peptide exhibited a marked increase (87 +/- 8 vs 46 +/- 6 pmol/L, p = 0.0003; 637 +/- 62 vs 381 +/- 76 pmol/L, p < 0.03) demonstrating insulin resistance in basal conditions.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
10656171-6	1999	glucose tolerance factor KG (2.0 +/- 0.2 vs 2.2 +/- 0.1% min-1), SG (0.035 +/- 0.004 vs 0.032 +/- 0.007 min-1) and S1 [3.5 +/- 0.5 vs 3.8 +/- 0.3 10(4) min-1 (microU/mL)] were similar, both basal insulin and C-peptide exhibited a marked increase (87 +/- 8 vs 46 +/- 6 pmol/L, p = 0.0003; 637 +/- 62 vs 381 +/- 76 pmol/L, p < 0.03) demonstrating insulin resistance in basal conditions.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
10457099-6	1999	Maximal in vivo glycogenolytic rates of 207 +/- 48 mM ATP min-1 were obtained within 15 s, decreasing to 72 +/- 34 mM ATP min-1 by the end of 30 s. In contrast, aerobic ATP synthesis rates achieved 85 +/- 2 % of their maximal capacity within 9 s and did not change throughout the exercise.	Adenosine Triphosphate	54-57	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
10500039-4	1999	Two doses of Ang II (0.5 and 3 ng x kg(-1) x min(-1) over 30 minutes each) increased blood pressure, plasma aldosterone, glomerular filtration rate, and filtration fraction and decreased renal blood flow.	Aldosterone	108-119	CD59 molecule (CD59 blood group)	Homo sapiens	45-51
10457099-6	1999	Maximal in vivo glycogenolytic rates of 207 +/- 48 mM ATP min-1 were obtained within 15 s, decreasing to 72 +/- 34 mM ATP min-1 by the end of 30 s. In contrast, aerobic ATP synthesis rates achieved 85 +/- 2 % of their maximal capacity within 9 s and did not change throughout the exercise.	Adenosine Triphosphate	118-121	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
10457099-6	1999	Maximal in vivo glycogenolytic rates of 207 +/- 48 mM ATP min-1 were obtained within 15 s, decreasing to 72 +/- 34 mM ATP min-1 by the end of 30 s. In contrast, aerobic ATP synthesis rates achieved 85 +/- 2 % of their maximal capacity within 9 s and did not change throughout the exercise.	Adenosine Triphosphate	118-121	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
10510146-5	1999	RESULTS: L-NMMA caused the expected increase in mean arterial pressure (96+/-2.6 vs 89+/-3.3 mmHg P<0.05 [mean+/-s.e.mean]), and a reduction in heart rate (59+/-3.6 vs 67+/-2.5 beats min-1 P<0.05).	omega-N-Methylarginine	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
10510163-9	1999	In the infused arm blood flow increased significantly in a dose-related manner during the first series of nebivolol infusions from 2.76+/-0.39 ml min-1-1 100 ml forearm-1 during the baseline period to 4.40+/-0.60 ml min-1-1 100 ml forearm-1 (mean+/-s.e.	Nebivolol	106-115	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
10510163-9	1999	In the infused arm blood flow increased significantly in a dose-related manner during the first series of nebivolol infusions from 2.76+/-0.39 ml min-1-1 100 ml forearm-1 during the baseline period to 4.40+/-0.60 ml min-1-1 100 ml forearm-1 (mean+/-s.e.	Nebivolol	106-115	CD59 molecule (CD59 blood group)	Homo sapiens	216-221
10510163-11	1999	L-NMMA antagonized the vasodilator effect of nebivolol: baseline blood flow in the infused arm was 2.41+/-0.53 ml min-1 100 ml forearm-1 and 2.94+/-0.42 ml min-1 100 ml forearm-1 during coinfusion of the top dose of nebivolol with L-NMMA (P=0.0006 for an effect of L-NMMA on nebivolol response).	omega-N-Methylarginine	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
10510163-11	1999	L-NMMA antagonized the vasodilator effect of nebivolol: baseline blood flow in the infused arm was 2.41+/-0.53 ml min-1 100 ml forearm-1 and 2.94+/-0.42 ml min-1 100 ml forearm-1 during coinfusion of the top dose of nebivolol with L-NMMA (P=0.0006 for an effect of L-NMMA on nebivolol response).	omega-N-Methylarginine	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
10510163-11	1999	L-NMMA antagonized the vasodilator effect of nebivolol: baseline blood flow in the infused arm was 2.41+/-0.53 ml min-1 100 ml forearm-1 and 2.94+/-0.42 ml min-1 100 ml forearm-1 during coinfusion of the top dose of nebivolol with L-NMMA (P=0.0006 for an effect of L-NMMA on nebivolol response).	Nebivolol	45-54	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
10510163-11	1999	L-NMMA antagonized the vasodilator effect of nebivolol: baseline blood flow in the infused arm was 2.41+/-0.53 ml min-1 100 ml forearm-1 and 2.94+/-0.42 ml min-1 100 ml forearm-1 during coinfusion of the top dose of nebivolol with L-NMMA (P=0.0006 for an effect of L-NMMA on nebivolol response).	Nebivolol	45-54	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
10655908-8	1999	Simultaneously, an infusion of ketamine 2.5 micrograms kg-1 min-1 or saline was started.	Ketamine	31-39	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
10490161-5	1999	infusion of propofol at a rate of 50 mg x min(-1) until loss of eyelash reflex and responses to verbal commands, which were judged by a blinded observer.	Propofol	12-20	CD59 molecule (CD59 blood group)	Homo sapiens	42-48
10549459-5	1999	During the maintenance fentanyl was delivered at 6.1 +/- 4.6 micrograms kg-1 h-1 and remifentanil at 0.15 +/- 0.07 microgram kg-1 min-1.	Remifentanil	85-97	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
10484566-2	1999	At 2.5, 5, and 10 microg x kg(-1) x min(-1), dobutamine induced significant increases in energy expenditure, lipid oxidation, and lipolysis.	Dobutamine	45-55	CD59 molecule (CD59 blood group)	Homo sapiens	36-42
10484566-3	1999	The beta(1)-adrenoceptor antagonist atenolol (bolus: 42.5 microg/kg, infusion: 1.02 microg x kg(-1) x min(-1)) blocked all dobutamine-induced effects on thermogenesis and lipid utilization.	Atenolol	36-44	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
10484566-3	1999	The beta(1)-adrenoceptor antagonist atenolol (bolus: 42.5 microg/kg, infusion: 1.02 microg x kg(-1) x min(-1)) blocked all dobutamine-induced effects on thermogenesis and lipid utilization.	Dobutamine	123-133	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
10484566-7	1999	Therefore, we conclude that dobutamine can be used as a selective beta(1)-adrenoceptor agonist at dosages </=10 microg x kg(-1) x min(-1) in in vivo studies on human thermogenesis and lipid utilization.	Dobutamine	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	133-139
10488706-6	1999	Peripheral glucose uptake in liver cirrhosis was 6.1+/-0.7 mg x kg(-1) x min(-1), which was lower than that in healthy volunteers (10.5+/-0.9 mg x kg(-1) x min(-1), p<0.05) and in chronic active hepatitis (8.4+/-0.3 mg x kg(-1) x min(-1), p<0.05).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	73-79
10488706-6	1999	Peripheral glucose uptake in liver cirrhosis was 6.1+/-0.7 mg x kg(-1) x min(-1), which was lower than that in healthy volunteers (10.5+/-0.9 mg x kg(-1) x min(-1), p<0.05) and in chronic active hepatitis (8.4+/-0.3 mg x kg(-1) x min(-1), p<0.05).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	156-162
10488706-6	1999	Peripheral glucose uptake in liver cirrhosis was 6.1+/-0.7 mg x kg(-1) x min(-1), which was lower than that in healthy volunteers (10.5+/-0.9 mg x kg(-1) x min(-1), p<0.05) and in chronic active hepatitis (8.4+/-0.3 mg x kg(-1) x min(-1), p<0.05).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	156-162
10510146-7	1999	Phenylephrine 0.5 microg kg-1 min-1 produced very similar haemodynamic effects to L-NMMA, and also suppressed the renin response to frusemide (1.43+/-0.290 vs 2.67+/-0.342 ng ml-1 h-1 P<0.	Phenylephrine	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
10510146-7	1999	Phenylephrine 0.5 microg kg-1 min-1 produced very similar haemodynamic effects to L-NMMA, and also suppressed the renin response to frusemide (1.43+/-0.290 vs 2.67+/-0.342 ng ml-1 h-1 P<0.	Furosemide	132-141	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
10475994-4	1999	SUBJECTS AND DESIGN: Thirty-six healthy men and 30 women, aged 20-69 years, underwent measurements of forearm blood flow (FBF) at rest and during local infusions of 2 and 4 microg min-1 of metacholine (evaluating EDV) and 5 and 10 microg min-1 of sodium nitroprusside (evaluating endothelium-independent vasodilation, EIDV) and during reactive hyperaemia by venous occlusion plethysmography.	metacholine	189-200	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
10533188-14	1999	Additionally, in patients with severely reduced kidney function (EDTA clearance < 20 ml.min-1), it only provides a rough estimate.	Edetic Acid	65-69	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
10536644-2	1999	Following administration of atropine, each subject was given an infusion of isoproterenol at incremental doses from 0.010 to 0.030 microgram kg-1 min-1.	Isoproterenol	76-89	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
10421658-5	1999	Rates for ATP-dependent transport of MGB and BGB (0.5 micromol/L each) by human MRP2 were 183 and 104 pmol x mg protein(-1) x min(-1), respectively.	Adenosine Triphosphate	10-13	CD59 molecule (CD59 blood group)	Homo sapiens	126-132
10417507-2	1999	METHODS: In nine healthy male volunteers, we measured the effect of infusion of saline into the brachial artery at a rate of 2 ml/100 ml forearm min-1 on FBF ratio during control, mental arithmetic (MAR) and lower body negative pressure (LBNP) at -40 mmHg.	Sodium Chloride	80-86	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
10618931-6	1999	Sevoflurane reduced AHVR from 14.5 (SEM 1.2) to 11.6 (1.6) litre min-1, and the off-response at cessation of hypoxia from 7.1 (1.1) to 6.3 (1.4) litre min-1.	Sevoflurane	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
10618931-6	1999	Sevoflurane reduced AHVR from 14.5 (SEM 1.2) to 11.6 (1.6) litre min-1, and the off-response at cessation of hypoxia from 7.1 (1.1) to 6.3 (1.4) litre min-1.	Sevoflurane	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
10618931-7	1999	The magnitude of HVD was slightly increased by sevoflurane from 8.2 (1.1) to 10.6 (2.8) litre min-1.	Sevoflurane	47-58	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
10457152-4	1999	RESULTS: The permeability-surface area product (PS) for glucose transport from the blood into the brain, PS1, was 0.145 (0.102-0.211) (median and quartiles), 0.146 (0.113-0.259), and 0.157 (0.133-0.181) ml g-1 min-1 before, during, and after insulin challenge, respectively.	Glucose	56-63	CD59 molecule (CD59 blood group)	Homo sapiens	210-215
10457152-5	1999	In six of the subjects, PS for transport from brain to blood over the brain glucose distribution volume, PS2/Ve decreased under hyperinsulinemia, from a baseline value of 6.56 (3.0-14.9) to 3.86 (1.41-5.32), and restored to a value of 3.8 (2.8-12.1) min-1 after insulin challenge.	Glucose	76-83	CD59 molecule (CD59 blood group)	Homo sapiens	250-255
10421658-5	1999	Rates for ATP-dependent transport of MGB and BGB (0.5 micromol/L each) by human MRP2 were 183 and 104 pmol x mg protein(-1) x min(-1), respectively.	ZINC17328551	37-40	CD59 molecule (CD59 blood group)	Homo sapiens	126-132
10457450-3	1999	Only 1-3 ml min-1 of helium carrier gas from the gas chromatograph was necessary for sustaining the plasma while 0.15-1.5 ml min-1 of hydrogen was added as reagent gas.	Helium	21-27	CD59 molecule (CD59 blood group)	Homo sapiens	12-17
10546471-6	1999	In 29 patients enrolled, the mean (+/- SD) O2 flow in L.min-1 was 1.5 +/- 0.6 during sleep, 1.4 +/- 0.6 during rest and 2.3 +/- 1.1 during exercise.	Oxygen	43-45	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
12567450-2	1999	METHODS: Vesicles released from normal RBCs under ATP depletion or storage, are rich in CD59.	Adenosine Triphosphate	50-53	CD59 molecule (CD59 blood group)	Homo sapiens	88-92
10457450-3	1999	Only 1-3 ml min-1 of helium carrier gas from the gas chromatograph was necessary for sustaining the plasma while 0.15-1.5 ml min-1 of hydrogen was added as reagent gas.	Hydrogen	134-142	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
10388716-2	1999	Thioploca is able to store internally high concentrations of sulfur globules and nitrate. It has been previously hypothesized that these large vacuolated bacteria can oxidize sulfide by reducing their internally stored nitrate. We examined this nitrate reduction by incubation experiments of washed Thioploca sheaths with trichomes in combination with 15N compounds and mass spectrometry and found that these Thioploca samples produce ammonium at a rate of 1 nmol min-1 mg of protein-1.	Sulfur	62-68	CD59 molecule (CD59 blood group)	Homo sapiens	465-470
10389781-5	1999	The remifentanil group received remifentanil 0.2 microg x kg(-1) x min(-1) and enough desflurane to prevent movement, typically 3.2%-3.6%.	Remifentanil	4-16	CD59 molecule (CD59 blood group)	Homo sapiens	67-73
10388716-4	1999	Sulfate was shown to be the end product of sulfide oxidation and was observed at a rate of 2 to 3 nmol min-1 mg of protein-1.	Sulfates	1-8	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
10417465-6	1999	In all groups, oxygen was insufflated under the drapes at a constant flow of 21.min-1.	Oxygen	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
10388716-4	1999	Sulfate was shown to be the end product of sulfide oxidation and was observed at a rate of 2 to 3 nmol min-1 mg of protein-1.	Sulfides	44-51	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
10417465-9	1999	An oxygen supply of 21.min-1 prevented hypoxaemia but not hypercapnia.	Oxygen	3-9	CD59 molecule (CD59 blood group)	Homo sapiens	23-28
10388716-6	1999	[2-14C]acetate incorporation was 0.4 nmol min-1 mg of protein-1, which is equal to the CO2 fixation rate, and no 14CO2 production was detected.	2-14c]acetate 	1-15	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
10455256-3	1999	Application to rats of a transdermal patch that releases doses of nitroglycerin comparable to those used in man (40, 80, 160 and 400 ng min(-1) rat(-1)) reduced gastric damage induced by indomethacin (25 mg kg(-1), p.o.	Nitroglycerin	66-79	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
10455256-3	1999	Application to rats of a transdermal patch that releases doses of nitroglycerin comparable to those used in man (40, 80, 160 and 400 ng min(-1) rat(-1)) reduced gastric damage induced by indomethacin (25 mg kg(-1), p.o.	Indomethacin	187-199	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
10455256-5	1999	The nitroglycerin patch (160 ng min(-1) rat(-1)) also diminished damage by oral administration (1 ml) of acidified bile salts (100 mg kg(-1) taurocholic acid in 150 mM HCl) or 50% ethanol.	Nitroglycerin	4-17	CD59 molecule (CD59 blood group)	Homo sapiens	32-38
10455256-5	1999	The nitroglycerin patch (160 ng min(-1) rat(-1)) also diminished damage by oral administration (1 ml) of acidified bile salts (100 mg kg(-1) taurocholic acid in 150 mM HCl) or 50% ethanol.	Bile Acids and Salts	115-125	CD59 molecule (CD59 blood group)	Homo sapiens	32-38
10455256-5	1999	The nitroglycerin patch (160 ng min(-1) rat(-1)) also diminished damage by oral administration (1 ml) of acidified bile salts (100 mg kg(-1) taurocholic acid in 150 mM HCl) or 50% ethanol.	Taurocholic Acid	141-157	CD59 molecule (CD59 blood group)	Homo sapiens	32-38
10455256-5	1999	The nitroglycerin patch (160 ng min(-1) rat(-1)) also diminished damage by oral administration (1 ml) of acidified bile salts (100 mg kg(-1) taurocholic acid in 150 mM HCl) or 50% ethanol.	Hydrochloric Acid	168-171	CD59 molecule (CD59 blood group)	Homo sapiens	32-38
10455256-6	1999	Transdermal nitroglycerin (160 ng min(-1) rat(-1)) did not influence basal gastric blood flow, as measured by lasser-doppler flowmetry, but prevented its reduction by indomethacin.	Nitroglycerin	12-25	CD59 molecule (CD59 blood group)	Homo sapiens	34-40
10455256-6	1999	Transdermal nitroglycerin (160 ng min(-1) rat(-1)) did not influence basal gastric blood flow, as measured by lasser-doppler flowmetry, but prevented its reduction by indomethacin.	Indomethacin	167-179	CD59 molecule (CD59 blood group)	Homo sapiens	34-40
10455256-7	1999	Transdermal nitroglycerin (160 ng min(-1) rat(-1)) prevented in vivo leukocyte rolling and adherence in the rat mesentery microvessels superfused with indomethacin, as evaluated by intravital microscopy.	Nitroglycerin	12-25	CD59 molecule (CD59 blood group)	Homo sapiens	34-40
10455256-7	1999	Transdermal nitroglycerin (160 ng min(-1) rat(-1)) prevented in vivo leukocyte rolling and adherence in the rat mesentery microvessels superfused with indomethacin, as evaluated by intravital microscopy.	Indomethacin	151-163	CD59 molecule (CD59 blood group)	Homo sapiens	34-40
10451789-5	1999	More rapid reduction occurred in SD1n during the low-intensity level of dynamic arm exercise than during dynamic leg exercise without beta-blockade (e.g. 11 +/- 6 vs. 20 +/- 10 at the oxygen consumption level of 1.2 l min-1; P < 0.001) and with beta-blockade (e.g. 13 +/- 4 vs. 25 +/- 10 at the level of 1.0 l min-1; P < 0.05), and the mean HR was significantly higher during submaximal arm work than during leg work in both cases (e.g. during beta-blockade 81 +/- 12 vs. 74 +/- 6 beats min-1 at the level of 1.0 l min-1; P < 0.05).	sd1n	33-37	CD59 molecule (CD59 blood group)	Homo sapiens	218-223
10442969-2	1999	METHODS: Anesthesia was induced with 2-3 mg x kg(-1) propofol and 1 microg x kg(-1) remifentanil and maintained with 75 microg x kg(-1) x min(-1) propofol and propofol initial infusion of 0.2 microg x kg(-1) x min(-1) propofol.	Propofol	146-154	CD59 molecule (CD59 blood group)	Homo sapiens	138-144
10442969-2	1999	METHODS: Anesthesia was induced with 2-3 mg x kg(-1) propofol and 1 microg x kg(-1) remifentanil and maintained with 75 microg x kg(-1) x min(-1) propofol and propofol initial infusion of 0.2 microg x kg(-1) x min(-1) propofol.	Propofol	146-154	CD59 molecule (CD59 blood group)	Homo sapiens	138-144
10442969-2	1999	METHODS: Anesthesia was induced with 2-3 mg x kg(-1) propofol and 1 microg x kg(-1) remifentanil and maintained with 75 microg x kg(-1) x min(-1) propofol and propofol initial infusion of 0.2 microg x kg(-1) x min(-1) propofol.	Propofol	146-154	CD59 molecule (CD59 blood group)	Homo sapiens	138-144
10464829-5	1999	Eformoterol Turbohaler (FT) achieved a greater increase in morning PEF than salmeterol Accuhaler (SA) from randomisation to 4 weeks; the increase shown in the eformoterol Turbohaler group was 28.9 1 min-1 compared to 19.91 min-1 for the salmeterol Accuhaler group.	eformoterol turbohaler	0-22	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
10387023-5	1999	It was regioselectively hydroxylated by CYP 2C18 at position 5 of its thiophene ring with a KM value of 9 +/- 1 microM and a kcat value of 125 +/- 25 min-1, which are the highest described so far for a CYP 2C.	Thiophenes	70-79	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
18967601-4	1999	The detection limit was 0.5 ppb for nitrogen dioxide with a sampling time of 8 min and a flow rate of 60 ml min(-1).	Nitrogen	36-44	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
10383490-4	1999	Control muscles oxidized DCFH at a rate of 0.32 +/- 0.1 greyscale units min-1.	DCFH	25-29	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
10476312-5	1999	This was also confirmed in the FSIGT where the glucose tolerance index (KG) was 0.6 +/- 0.1% min-1 in D vs 1.8 +/- 0.2 in C and 1.5 +/- 0.2 in E (p < 0.0002).	Glucose	47-54	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
10403868-5	1999	The minimum inspired oxygen fraction measured with the remaining devices was greater than with the T-piece at an oxygen flow of 10 l.min-1.	Oxygen	21-27	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
10403868-5	1999	The minimum inspired oxygen fraction measured with the remaining devices was greater than with the T-piece at an oxygen flow of 10 l.min-1.	Oxygen	113-119	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
10464529-8	1999	An isolated bradycardia (HR < 60 b.min-1) was treated with atropine (0.5-1 mg i.v.).	Atropine	62-70	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
10464538-2	1999	We report the case of a 43-year-old schizophrenic who sustained, after 12 days of treatment including olanzapine (20 mg.day-1), carbamazepine, levomepromazine and alprazolan, a severe shock with bradycardia (HR: 40 b.min-1), circulatory collapse (SAP: 60 mmHg), hypothermia (T: 27 degrees C), coma and disseminated intravascular coagulation.	Olanzapine	102-112	CD59 molecule (CD59 blood group)	Homo sapiens	217-222
10464538-2	1999	We report the case of a 43-year-old schizophrenic who sustained, after 12 days of treatment including olanzapine (20 mg.day-1), carbamazepine, levomepromazine and alprazolan, a severe shock with bradycardia (HR: 40 b.min-1), circulatory collapse (SAP: 60 mmHg), hypothermia (T: 27 degrees C), coma and disseminated intravascular coagulation.	Carbamazepine	128-141	CD59 molecule (CD59 blood group)	Homo sapiens	217-222
10464538-2	1999	We report the case of a 43-year-old schizophrenic who sustained, after 12 days of treatment including olanzapine (20 mg.day-1), carbamazepine, levomepromazine and alprazolan, a severe shock with bradycardia (HR: 40 b.min-1), circulatory collapse (SAP: 60 mmHg), hypothermia (T: 27 degrees C), coma and disseminated intravascular coagulation.	Methotrimeprazine	143-158	CD59 molecule (CD59 blood group)	Homo sapiens	217-222
10464538-2	1999	We report the case of a 43-year-old schizophrenic who sustained, after 12 days of treatment including olanzapine (20 mg.day-1), carbamazepine, levomepromazine and alprazolan, a severe shock with bradycardia (HR: 40 b.min-1), circulatory collapse (SAP: 60 mmHg), hypothermia (T: 27 degrees C), coma and disseminated intravascular coagulation.	Alprazolam	163-173	CD59 molecule (CD59 blood group)	Homo sapiens	217-222
10391607-4	1999	Remifentanil infusion, 0.2-1.0 microg x kg(-1) x min(-1), was used from induction to emergence of general anesthesia.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
10411631-4	1999	Km values for citral were 4 microM for E1, 1 microM for E2 and 0.1 microM for E3; Vmax values were highest for E1 (73 nmol x min-1 x mg-1), intermediate for E2 (17 nmol x min-1 x mg-1) and lowest (0.07 nmol x min-1 x mg-1) for the E3 isozyme.	citral	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
10411631-4	1999	Km values for citral were 4 microM for E1, 1 microM for E2 and 0.1 microM for E3; Vmax values were highest for E1 (73 nmol x min-1 x mg-1), intermediate for E2 (17 nmol x min-1 x mg-1) and lowest (0.07 nmol x min-1 x mg-1) for the E3 isozyme.	citral	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
10411631-4	1999	Km values for citral were 4 microM for E1, 1 microM for E2 and 0.1 microM for E3; Vmax values were highest for E1 (73 nmol x min-1 x mg-1), intermediate for E2 (17 nmol x min-1 x mg-1) and lowest (0.07 nmol x min-1 x mg-1) for the E3 isozyme.	citral	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
10368358-6	1999	The 56% increase in glucose uptake after ET (4.95 +/- 0.90 vs. 7.74 +/- 0.82 mg. min-1.	Glucose	20-27	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
10354495-3	1999	However, in the absence of NADH, reduced coenzyme Q10 (Q10H2=ubiquinol) was oxidized at a rate of 15+/-6 nmol min-1 mg protein-1 depending on degree of purification.	q10h2	55-60	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
10354495-3	1999	However, in the absence of NADH, reduced coenzyme Q10 (Q10H2=ubiquinol) was oxidized at a rate of 15+/-6 nmol min-1 mg protein-1 depending on degree of purification.	ubiquinol	61-70	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
10319775-5	1999	RESULTS: Sevoflurane reduced the hypoxic ventilatory sensitivity significantly in both sexes (men: control, 0.62 +/- 0.17 vs. sevoflurane, 0.38 +/- 0.19 l x min(-1) x %(-1); women: control, 0.52 +/- 0.30 vs. sevoflurane, 0.34 +/- 0.15 l x min(-1) x %(-1)).	Sevoflurane	9-20	CD59 molecule (CD59 blood group)	Homo sapiens	157-163
10319775-5	1999	RESULTS: Sevoflurane reduced the hypoxic ventilatory sensitivity significantly in both sexes (men: control, 0.62 +/- 0.17 vs. sevoflurane, 0.38 +/- 0.19 l x min(-1) x %(-1); women: control, 0.52 +/- 0.30 vs. sevoflurane, 0.34 +/- 0.15 l x min(-1) x %(-1)).	Sevoflurane	9-20	CD59 molecule (CD59 blood group)	Homo sapiens	239-245
10319781-6	1999	RESULTS: In carbon dioxide studies in men, morphine reduced Gc from 1.61 +/- 0.33 to 1.23 +/- 0.12 l x min(-1) x mmHg(-1) (P < 0.05) without affecting Gp (control, 0.41 +/- 0.16 and morphine, 0.49 +/- 0.12 l x min(-1) x mmHg(-1), not significant).	Morphine	43-51	CD59 molecule (CD59 blood group)	Homo sapiens	103-109
10319781-6	1999	RESULTS: In carbon dioxide studies in men, morphine reduced Gc from 1.61 +/- 0.33 to 1.23 +/- 0.12 l x min(-1) x mmHg(-1) (P < 0.05) without affecting Gp (control, 0.41 +/- 0.16 and morphine, 0.49 +/- 0.12 l x min(-1) x mmHg(-1), not significant).	Morphine	43-51	CD59 molecule (CD59 blood group)	Homo sapiens	213-219
10319781-7	1999	In carbon dioxide studies in women, morphine reduced Gc, from 1.51 +/- 0.74 to 1.17 +/- 0.52 l x min(-1) x mmHg(-1) (P < 0.05), and Gp, from 0.54 +/- 0.19 to 0.39 +/- 0.22 l x min(-1) x mmHg(-1) (P < 0.05).	Morphine	36-44	CD59 molecule (CD59 blood group)	Homo sapiens	97-103
10319781-7	1999	In carbon dioxide studies in women, morphine reduced Gc, from 1.51 +/- 0.74 to 1.17 +/- 0.52 l x min(-1) x mmHg(-1) (P < 0.05), and Gp, from 0.54 +/- 0.19 to 0.39 +/- 0.22 l x min(-1) x mmHg(-1) (P < 0.05).	Morphine	36-44	CD59 molecule (CD59 blood group)	Homo sapiens	179-185
10319781-9	1999	In hypoxic studies, morphine depressed the hyperventilatory response at the initiation of hypoxia more in women than in men (0.54 +/- 0.23 vs. 0.26 +/- 0.34 l x min(-1) x %(-1), respectively; P < 0.05).	Morphine	20-28	CD59 molecule (CD59 blood group)	Homo sapiens	161-167
10329953-10	1999	min-1, i.e., 16% of the cellular ATP per hour, while ATP remained constant.	Adenosine Triphosphate	33-36	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
10330014-5	1999	min-1, intra-SMA) reduced oxygen consumption by 25.1 +/- 2.9 from 73.1 +/- 10.8 micromol.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
10372218-11	1999	A tobramycin clearance below 80 ml/min/1.73 m2 was associated with average 80% and 33% higher creatinine clearance values according to the Cockcroft-method and the direct method, respectively.	Tobramycin	2-12	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
10372218-11	1999	A tobramycin clearance below 80 ml/min/1.73 m2 was associated with average 80% and 33% higher creatinine clearance values according to the Cockcroft-method and the direct method, respectively.	Creatinine	94-104	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
10332951-9	1999	Heart rate and oxygen consumption increased 75+/-4 bpm and 26.3+/-1.4 ml O2/kg x min(-1) from supine resting values, respectively.	Oxygen	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
10332951-9	1999	Heart rate and oxygen consumption increased 75+/-4 bpm and 26.3+/-1.4 ml O2/kg x min(-1) from supine resting values, respectively.	Oxygen	73-75	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
10367111-2	1999	The turnover numbers were estimated to be 17.6 and 19.6 min-1 in the presence of Mg2+ or Ca2+ ions (5 mmol/l) in the test system, respectively.	magnesium ion	81-85	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
10367111-3	1999	Inclusion of b5 in the vesicular CYP3A4: reductase system results in a slightly lower nifedipine oxidase activity of 16.9 min-1 in the presence of Mg2+ ions.	magnesium ion	147-151	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
10336577-6	1999	RESULTS: Clevidipine was administered up to a target dose rate of 48 nmol min-1 kg-1, where a pre-determined escape criterion was reached (HR>120 beats min-1 ) and the study was stopped.	clevidipine	9-20	CD59 molecule (CD59 blood group)	Homo sapiens	74-84
10336577-6	1999	RESULTS: Clevidipine was administered up to a target dose rate of 48 nmol min-1 kg-1, where a pre-determined escape criterion was reached (HR>120 beats min-1 ) and the study was stopped.	clevidipine	9-20	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
10336577-15	1999	CONCLUSIONS: Clevidipine is well tolerated and safe in healthy volunteers at dose rates up to at least 48 nmol min-1 kg-1.	clevidipine	13-24	CD59 molecule (CD59 blood group)	Homo sapiens	111-121
10336578-10	1999	5+/-14.5 min and clearance of 12.2+/-3.5 ml min-1 kg-1 and caused a small hypertensive response, decreased CO by 13%, FPA by 26%, exhNO by 46% and increased systemic vascular resistance by 16% (P<0.05 each) 15 min after start of drug administration.	fpa	118-121	CD59 molecule (CD59 blood group)	Homo sapiens	44-54
10349922-9	1999	CONCLUSION: During stable sevoflurane anesthesia, peak HR increase > or = 10 beats x min(-1) should be regarded as a positive response with end-tidal sevoflurane concentration < or = 1%, and peak SBP increase > or = 15 mmHg is applicable at sevoflurane concentrations between 0.5 and 2%.	Sevoflurane	26-37	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
10349922-9	1999	CONCLUSION: During stable sevoflurane anesthesia, peak HR increase > or = 10 beats x min(-1) should be regarded as a positive response with end-tidal sevoflurane concentration < or = 1%, and peak SBP increase > or = 15 mmHg is applicable at sevoflurane concentrations between 0.5 and 2%.	Sevoflurane	153-164	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
10349922-9	1999	CONCLUSION: During stable sevoflurane anesthesia, peak HR increase > or = 10 beats x min(-1) should be regarded as a positive response with end-tidal sevoflurane concentration < or = 1%, and peak SBP increase > or = 15 mmHg is applicable at sevoflurane concentrations between 0.5 and 2%.	Sevoflurane	153-164	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
10331398-10	1999	Net splanchnic lactate balance switched from a basal net uptake (3.2+/-0.6 micromol kg(-1) x min(-1) to a net output between 60 and 120 min and tended to zero thereafter.	Lactic Acid	15-22	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
10382089-4	1999	Dobutamine (up to 40 micrograms kg-1 min-1)-atropine (up to 1 mg) stress echocardiography in conjunction with stress-reinjection 201Tl SPET was performed for the evaluation of myocardial ischaemia in 90 patients with previous myocardial infarction who underwent coronary angiography.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
11529112-6	1999	The tape could be used to detect down to 0.08 ppm (World Health Organization standard) of formaldehyde with a sampling time of 30 min and a flow rate of 100 mL min-1.	Formaldehyde	90-102	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
10231450-7	1999	RESULTS: Considering an inulin clearance of less than 80 ml/min/1.73 m2, the cut-off value for serum creatinine was 11.5 mumol/liter for men and 90 mumol/liter for women.	Creatinine	101-111	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
10233113-2	1999	We further hypothesized that an increased exercise SaO2 with AA exposure would enhance O2 transport and improve both peak O2 uptake (VO2 peak; ml x kg-1 x min-1) and submaximal exercise time to exhaustion (Exh; min) in the midluteal phase.	sao2	51-55	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
10233113-2	1999	We further hypothesized that an increased exercise SaO2 with AA exposure would enhance O2 transport and improve both peak O2 uptake (VO2 peak; ml x kg-1 x min-1) and submaximal exercise time to exhaustion (Exh; min) in the midluteal phase.	Oxygen	53-55	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
10233116-7	1999	VE increased during Acz and Con after the switch into hypoxia; the hypoxic ventilatory response was significantly lower after Acz compared with Con [Acz, change (Delta) in VE/DeltaSaO2 = 1.54 +/- 0.10 l. min-1.	Acetazolamide	126-129	CD59 molecule (CD59 blood group)	Homo sapiens	204-209
10233116-7	1999	VE increased during Acz and Con after the switch into hypoxia; the hypoxic ventilatory response was significantly lower after Acz compared with Con [Acz, change (Delta) in VE/DeltaSaO2 = 1.54 +/- 0.10 l. min-1.	Acetazolamide	126-129	CD59 molecule (CD59 blood group)	Homo sapiens	204-209
10331889-4	1999	RESULTS: In both genders, VO2max expressed in mL x kg(-1) x min(-1) was negatively correlated with plasma triglyceride levels in apo E2 carriers and apo E3 homozygotes (-0.55< or =r< or =0.31; P<0.05), whereas these associations were not found in apo E4 groups.	Triglycerides	106-118	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
10455827-4	1999	Dopexamine caused a significant increase in heart rate (116 vs. 106 beat.min-1), and urine output (103 vs. 69 ml.h-1).	dopexamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
18967542-6	1999	The 90% response time of the sensor system was within 3.5 min for a 0.5 mg dm(-3) cyanide solution, when the flow rate of the purging air was 1 dm(3) min(-1).	dm(-3) cyanide	75-89	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
10195511-10	1999	Because the use of methohexital (29.4 +/- 2.7 microg x kg(-1) x min(-1)) for sedation during breast biopsy procedures has a similar efficacy and recovery profile to that of propofol (36.8 +/- 15.9 microg x kg(-1) x min(-1)) and is less costly based on the amount infused, it seems to be a cost-effective alternative to propofol for sedation during local anesthesia.	Methohexital	19-31	CD59 molecule (CD59 blood group)	Homo sapiens	64-70
10195511-10	1999	Because the use of methohexital (29.4 +/- 2.7 microg x kg(-1) x min(-1)) for sedation during breast biopsy procedures has a similar efficacy and recovery profile to that of propofol (36.8 +/- 15.9 microg x kg(-1) x min(-1)) and is less costly based on the amount infused, it seems to be a cost-effective alternative to propofol for sedation during local anesthesia.	Methohexital	19-31	CD59 molecule (CD59 blood group)	Homo sapiens	215-221
10199815-4	1999	min-1 over 24 h. Bradykinin (10(-8)-10(-5) M) dose dependently increased acute PGE2 release by three orders of magnitude.	Dinoprostone	79-83	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
10201663-6	1999	Use of adenosine (mean +/- SEM, 166+/-17 microg x kg(-1) x min(-1)) was associated with a significantly greater decrease in systolic blood pressure and higher heart rate values compared with remifentanil (mean +/- SEM, 0.2+/-0.03 microg kg(-1) x min(-1)).	Adenosine	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	59-66
10201663-6	1999	Use of adenosine (mean +/- SEM, 166+/-17 microg x kg(-1) x min(-1)) was associated with a significantly greater decrease in systolic blood pressure and higher heart rate values compared with remifentanil (mean +/- SEM, 0.2+/-0.03 microg kg(-1) x min(-1)).	Adenosine	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	246-253
10455827-5	1999	Dopexamine produced a significant increase in oxygen delivery (infusion 548 ml O2.min-1.m-2; no infusion 492 ml O2.min-1.m-2) while prostacyclin caused a decrease (infusion 460 ml O2.min-1.m-2; no infusion 547 ml O2.min-1.m-2).	dopexamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
10455827-5	1999	Dopexamine produced a significant increase in oxygen delivery (infusion 548 ml O2.min-1.m-2; no infusion 492 ml O2.min-1.m-2) while prostacyclin caused a decrease (infusion 460 ml O2.min-1.m-2; no infusion 547 ml O2.min-1.m-2).	Oxygen	46-52	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
10232719-5	1999	RESULTS: Ra glucose increased from 11.8 +/- 1.2 to 16.8 +/- 3.2 micromol x kg(-1) x min(-1) two hours after hysterectomy (P < 0.05) with a correlation between the degree of increase and the time of peritoneal cavity exposure (r = 0.859, P = 0.006).	ra glucose	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
10201669-5	1999	RESULTS: Rapacuronium"s weight-normalized plasma clearance was 7.03 x (1 - 0.0507 x (HgB - 13)) ml x kg(-1) x min(-1), where HgB is the patient"s preoperative value for hemoglobin (g/100 ml); however, rapacuronium"s blood clearance (11.4+/-1.4 ml x kg(-1) x min(-1), mean +/- SD) did not vary with hemoglobin.	rapacuronium	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	110-116
10201669-5	1999	RESULTS: Rapacuronium"s weight-normalized plasma clearance was 7.03 x (1 - 0.0507 x (HgB - 13)) ml x kg(-1) x min(-1), where HgB is the patient"s preoperative value for hemoglobin (g/100 ml); however, rapacuronium"s blood clearance (11.4+/-1.4 ml x kg(-1) x min(-1), mean +/- SD) did not vary with hemoglobin.	rapacuronium	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	258-264
10232720-9	1999	Anaesthesia was maintained with 120-140 microg x kg(-1) x min(-1) propofol, nitrous oxide and oxygen to maintain vital signs within 20% of baseline.	Propofol	66-74	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
10353179-9	1999	Comparing the wall motion score index at rest with the index after DSE 5 and 10 micrograms.kg-1.min-1 dobutamine and after HBO2, there was significant improvement (P < 0.005).	Dobutamine	102-112	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
10234494-4	1999	All volunteers received on separate days a continuous infusion of dopamine 5 micrograms kg-1 min-1 on one occasion and normal saline on the other occasion.	Dopamine	66-74	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
10201017-11	1999	The mean creatinine clearance declined over the years from 76 to 45 ml/min/1.73 m2, and the incidence of hypertension increased to more than 80% of the patients.	Creatinine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
10376760-4	1999	Overall geometric mean (geometric SD) caffeine clearance was 1.34 ml min(-1) kg b.w.	Caffeine	38-46	CD59 molecule (CD59 blood group)	Homo sapiens	69-75
10464887-5	1999	Eformoterol Turbohaler (FT) achieved a greater increase in morning PEF than salmeterol Accuhaler (SA) from randomisation to 4 weeks; the increase shown in the eformoterol Turbohaler group was 28.9 l min-1 compared to 19.9 l min-1 for the salmeterol Accuhaler group.	eformoterol turbohaler	0-22	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
18967525-3	1999	The argon plasma is generated at 275 W radiofrequency power and 27.12 MHz and it has a very good stability and a low gas consumption of 0.4 l min(-1).	Argon	4-9	CD59 molecule (CD59 blood group)	Homo sapiens	142-148
10353179-10	1999	Differences between DSE 5 micrograms.kg-1.min-1 dobutamine and DSE 10 micrograms.kg-1.min-1 dobutamine and between HBO2 and DSE 10 micrograms.kg-1.min-1 dobutamine were also significant (P < 0.005).	Dobutamine	92-102	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
10353179-10	1999	Differences between DSE 5 micrograms.kg-1.min-1 dobutamine and DSE 10 micrograms.kg-1.min-1 dobutamine and between HBO2 and DSE 10 micrograms.kg-1.min-1 dobutamine were also significant (P < 0.005).	Dobutamine	92-102	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
10353179-10	1999	Differences between DSE 5 micrograms.kg-1.min-1 dobutamine and DSE 10 micrograms.kg-1.min-1 dobutamine and between HBO2 and DSE 10 micrograms.kg-1.min-1 dobutamine were also significant (P < 0.005).	Dobutamine	92-102	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
10353179-10	1999	Differences between DSE 5 micrograms.kg-1.min-1 dobutamine and DSE 10 micrograms.kg-1.min-1 dobutamine and between HBO2 and DSE 10 micrograms.kg-1.min-1 dobutamine were also significant (P < 0.005).	Dobutamine	92-102	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
10078670-9	1999	Halothane reduced metabolism 40+/-9% to 3.7+/-0.6 mg x 100 g(-1) x min(-1) (P< or =0.005).	Halothane	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	67-73
10434811-3	1999	In the non-parametric analysis, keo was found to have a mean value of 0.2 (range 0.1-0.36) min-1.	keo	32-35	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
10434828-2	1999	In a double-blind, placebo-controlled, crossover study, eight ASA 1 male volunteers received infusion of adenosine 100 micrograms kg-1 min-1 or placebo for 10 min.	Adenosine	105-114	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
10434829-6	1999	Median blood target concentration of propofol varied from 1.0 to 1.2 micrograms ml-1 and mean propofol consumption was 50.3 (SD 17.6) micrograms kg-1 min-1.	Propofol	94-102	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
10206087-2	1999	METHODS: Eight healthy male volunteers received 1030 nmol x min(-1) of clevidipine together with a tracer dose of 3[H]-clevidipine for 1 h as an i.v.	clevidipine	71-82	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
10206087-6	1999	RESULTS: A two-compartment model gave the best fit to the individual clevidipine blood levels, resulting in a mean blood clearance of 0.14 (0.03) l x min(-1) x kg(-1) and a mean volume of distribution at steady state of 0.6 (0.1) l x kg(-1).	clevidipine	69-80	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
10078877-4	1999	The baseline whole-brain oxygen consumption averaged 185 +/- 32 micromol hg(-1) min(-1) by the three-step method and 153 +/- 15 micromol hg(-1) min(-1) by the one-step method.	Oxygen	25-31	CD59 molecule (CD59 blood group)	Homo sapiens	80-86
10226173-10	1999	Administration of GTN (20 microg kg-1 min-1) significantly reduced the indomethacin-induced mucosal dysfunction.	Nitroglycerin	18-21	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
10226173-10	1999	Administration of GTN (20 microg kg-1 min-1) significantly reduced the indomethacin-induced mucosal dysfunction.	Indomethacin	71-83	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
10226173-11	1999	By contrast, higher doses of GTN (80 microg kg-1 min-1) exacerbated epithelial dysfunction induced by indomethacin.	Nitroglycerin	29-32	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
10226173-11	1999	By contrast, higher doses of GTN (80 microg kg-1 min-1) exacerbated epithelial dysfunction induced by indomethacin.	Indomethacin	102-114	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
10226173-12	1999	Elevated levels of carbonyls and myeloperoxidase (MPO) observed after indomethacin administration were significantly reduced, to the control values, when GTN (20 microg kg-1 min-1) was administered along with indomethacin.	Indomethacin	70-82	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
10226173-12	1999	Elevated levels of carbonyls and myeloperoxidase (MPO) observed after indomethacin administration were significantly reduced, to the control values, when GTN (20 microg kg-1 min-1) was administered along with indomethacin.	Nitroglycerin	154-157	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
10226179-13	1999	min-1) and the amount (rs = 0.75, P < 0001) and concentration (rs = 0.69, P < 0001) of 2H2O in the test drink, but there was no relationship (rs = 0.09, P = 0.5) between the rate of 2H accumulation in the blood and the volume of the drink consumed.	2h2o	93-97	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
10226181-7	1999	Mean CFCa in healthy subjects was (3.8+/-0.4) x 10(-3) ml (100 ml)-1 cmH2O-1 min-1, close to literature values.	cmh2o	69-74	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
10050023-9	1999	After 120 min Ra and rate of disappearance (Rd) of glucose were 51-52 micromol kg-1 min-1 during Fast, 73-74 micromol kg-1 min-1 during Lo-Glu and 117-119 micromol kg-1 min-1 during Hi-Glu.	Glucose	51-58	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
10050023-9	1999	After 120 min Ra and rate of disappearance (Rd) of glucose were 51-52 micromol kg-1 min-1 during Fast, 73-74 micromol kg-1 min-1 during Lo-Glu and 117-119 micromol kg-1 min-1 during Hi-Glu.	Glucose	51-58	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
10050023-9	1999	After 120 min Ra and rate of disappearance (Rd) of glucose were 51-52 micromol kg-1 min-1 during Fast, 73-74 micromol kg-1 min-1 during Lo-Glu and 117-119 micromol kg-1 min-1 during Hi-Glu.	Glucose	51-58	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
10334304-2	1999	In the postabsorptive state, the rate of glucose appearance was 11.5 +/- 0.6 micromol x kg(-1) x min(-1).	Glucose	41-48	CD59 molecule (CD59 blood group)	Homo sapiens	97-103
10334304-3	1999	Hepatic glucose production, calculated as the sum of net glucose output (9.8 +/- 0.8 micromol x kg(-1) x min(-1)) and splanchnic glucose uptake (2.2 +/- 0.3 micromol x kg(-1) x min(-1)) accounted for the entire rate of glucose appearance.	Glucose	8-15	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
10334304-6	1999	In the 60-h fasted state, the rate of glucose appearance was 8.2 +/- 0.3 micromol x kg(-1) x min(-1).	Glucose	38-45	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
10064071-5	1999	We found that raft patches formed by GPI-anchored CD59 protein and the ganglioside GM1 accumulate filamentous actin.	Glycosylphosphatidylinositols	37-40	CD59 molecule (CD59 blood group)	Homo sapiens	50-54
10091579-4	1999	The purified enzyme shows a latent Ca(2+)-dependent ATPase activity of 1.0 mumol.mg-1 min-1 and a Mg(2+)-dependent activity of 4.4 mumol.mg-1 .min-1.	magnesium ion	98-104	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
10682113-7	1999	Incubation of MC with anti-CD59 mAb abrogated the protective effect of CD59 (100% cytotoxicity).	Methylcholanthrene	14-16	CD59 molecule (CD59 blood group)	Homo sapiens	27-31
11529078-6	1999	The uptake rates, in ml min-1, for the terpenes on Chromosorb 106 were 0.36 for alpha-pinene, 0.36 for beta-pinene and 0.40 for delta 3-carene.	Terpenes	39-47	CD59 molecule (CD59 blood group)	Homo sapiens	24-29
10464856-4	1999	Aerosolized epoprostenol, equivalent to the maximum tolerated intravenous dose (31.2 micrograms), produced a 58% fall in pulmonary vascular resistance, increased the cardiac output by 42% and improved functional performance by one MET (3.5 ml kg-1 min-1 of oxygen uptake) without any significant side-effects.	Epoprostenol	12-24	CD59 molecule (CD59 blood group)	Homo sapiens	248-253
10075598-13	1999	The mean serum creatinine was 1.1+/-0.5 mg/dl, and the corresponding calculated creatinine clearance was 88+/-25 ml/min/1.73 m2.	Creatinine	80-90	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
10682113-5	1999	MC lines were positive for staining with anti-CD59 mAb.	Methylcholanthrene	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	46-50
10682113-6	1999	Western blotting analysis of MC membrane demonstrated a band with the same molecular weight as CD59.	Methylcholanthrene	29-31	CD59 molecule (CD59 blood group)	Homo sapiens	95-99
9895080-2	1999	They were randomized to receive one of the following initial dose regimens in double-blinded fashion: placebo or 0.04, 0.07, or 0.1 microg x kg(-1) x min(-1) remifentanil subsequently titrated to effect.	Remifentanil	158-170	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
9895080-5	1999	The remifentanil 50% effective dose for a composite sedation level > or =2 within 15 min of the start of drug infusion was estimated as 0.043 microg x kg(-1) x min(-1) (95% confidence interval 0.01, 0.059).	Remifentanil	4-16	CD59 molecule (CD59 blood group)	Homo sapiens	163-169
10084096-1	1999	This double-blind, randomized trial compared the onset of sedation with two patient-controlled sedation regimens, allowing a maximum of 16 or 25 mg min-1 propofol.	Propofol	154-162	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
10084096-5	1999	Patients receiving 16 mg min-1 propofol were not reliably sedated within 5 min and took significantly longer to develop slurred speech and amnesia (P < 0.01 for both).	Propofol	31-39	CD59 molecule (CD59 blood group)	Homo sapiens	25-30
10081704-7	1999	Similarly mean efflux at 6 min in the presence of A23187 was also significantly greater than control (6.5 +/- 1.9% min-1 versus 2.6 +/- 1.0% min-1, respectively, n = 3 placentas).	Calcimycin	50-56	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
10081704-7	1999	Similarly mean efflux at 6 min in the presence of A23187 was also significantly greater than control (6.5 +/- 1.9% min-1 versus 2.6 +/- 1.0% min-1, respectively, n = 3 placentas).	Calcimycin	50-56	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
11938728-5	1999	The tocopherols were eluted with methanol mobile phase at a flow rate of 1.0 ml.min-1 and detected by fluorescence(lambda exc = 295 nm, lambda em = 330 nm).	Tocopherols	4-15	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
10570897-8	1999	The latest serum creatinine and creatinine clearance averages were respectively 66 mumol/l and 105 ml/min/1.73 m2.	Creatinine	32-42	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
10364738-8	1999	Peak oxygen consumption rose from 573 +/- 84 to 750 +/- 59 ml x min-1, corresponding to an increase in cardiac index from 4.25 +/- 0.5 to 5.88 +/- 0.76 liters x min-1 x m-2.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
10364738-8	1999	Peak oxygen consumption rose from 573 +/- 84 to 750 +/- 59 ml x min-1, corresponding to an increase in cardiac index from 4.25 +/- 0.5 to 5.88 +/- 0.76 liters x min-1 x m-2.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
10464846-7	1999	There was a significant increase in both morning and evening PEF respectively, on bambuterol (28 l min-1, 20 l min-1, P < 0.05) and salmeterol (29 l min-1, P < 0.001; 23 l min-1, P < 0.01) when compared with run-in.	bambuterol	82-92	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
10464846-7	1999	There was a significant increase in both morning and evening PEF respectively, on bambuterol (28 l min-1, 20 l min-1, P < 0.05) and salmeterol (29 l min-1, P < 0.001; 23 l min-1, P < 0.01) when compared with run-in.	bambuterol	82-92	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
10464846-7	1999	There was a significant increase in both morning and evening PEF respectively, on bambuterol (28 l min-1, 20 l min-1, P < 0.05) and salmeterol (29 l min-1, P < 0.001; 23 l min-1, P < 0.01) when compared with run-in.	bambuterol	82-92	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
10464846-7	1999	There was a significant increase in both morning and evening PEF respectively, on bambuterol (28 l min-1, 20 l min-1, P < 0.05) and salmeterol (29 l min-1, P < 0.001; 23 l min-1, P < 0.01) when compared with run-in.	bambuterol	82-92	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
9846859-3	1998	DESIGN: Six volunteers received a primed, constant, intravenous infusion of [1-13C]acetate at a rate of 1.01 +/- 0.04 micromol x kg(-1) x min(-1) for 7 h. They ingested 20 g pure lactulose after 1 h of the tracer infusion.	[1-13c]acetate	76-90	CD59 molecule (CD59 blood group)	Homo sapiens	138-144
9846859-6	1998	Whole-body acetate turnover was 6.0 +/- 0.7 micromol x kg(-1) x min(-1).	Acetates	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	64-70
9846859-8	1998	Whole-body acetate turnover increased to 9.8 +/- 1.5 micromol x kg(-1) x min(-1) and later decreased almost to baseline values.	Acetates	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	73-79
9843739-8	1998	min-1, muscle total creatine concentration increased by 4.5 +/- 1.4 (P < 0.	Creatine	20-28	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9847266-9	1998	min-1 of almitrine with and without NO was determined.	Almitrine	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9847266-21	1998	min-1 dramatically increases PaO2 without apparent deleterious effect allowing a rapid reduction in inspired fraction of O2.	pao2	29-33	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9847266-21	1998	min-1 dramatically increases PaO2 without apparent deleterious effect allowing a rapid reduction in inspired fraction of O2.	Oxygen	31-33	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
10052723-4	1998	Cell membrane-associated regulators of complement, membrane cofactor protein (CD46), decay-accelerating factor (CD55) and protectin (CD59) were expressed on EA.hy 926 cells grown under normal oxygen tension.	Oxygen	192-198	CD59 molecule (CD59 blood group)	Homo sapiens	133-137
9834251-2	1998	Intravascular red blood cell (RBC) destruction is caused by increased sensitivity of the abnormal erythrocyte to complement-mediated lysis, due to the GPI absence of a membrane-bound glycosylphosphatidylinositol (GPI)-linked protein, which functions as an inhibitor of reactive lysis (CD59).	Glycosylphosphatidylinositols	183-211	CD59 molecule (CD59 blood group)	Homo sapiens	285-289
9834251-9	1998	Pretreatment of microvesicles, RBC eluate preparations, and HDL with phosphatidylinositol-specific, phospholipase C, abrogated protein transfer to deficient cells, indicating that increased cell-associated CD55 and CD59 levels were related to insertion of the intact GPI moiety, rather than to simple adhesion.	Phosphatidylinositols	69-89	CD59 molecule (CD59 blood group)	Homo sapiens	215-219
10682113-7	1999	Incubation of MC with anti-CD59 mAb abrogated the protective effect of CD59 (100% cytotoxicity).	Methylcholanthrene	14-16	CD59 molecule (CD59 blood group)	Homo sapiens	71-75
10682113-11	1999	These findings suggest that production of complement components and expression of CD59 on MCs could play a role both in peritoneal cavity infection (decreased complement production) and in peritoneal membrane damage (decreased CD59 expression and reduced remesothelialization owing to MC lysis).	Methylcholanthrene	90-92	CD59 molecule (CD59 blood group)	Homo sapiens	82-86
10682113-11	1999	These findings suggest that production of complement components and expression of CD59 on MCs could play a role both in peritoneal cavity infection (decreased complement production) and in peritoneal membrane damage (decreased CD59 expression and reduced remesothelialization owing to MC lysis).	Methylcholanthrene	90-92	CD59 molecule (CD59 blood group)	Homo sapiens	227-231
11263368-4	1998	In the experimental group, PGE1(0.5 microgram/kg.min-1) was injected intravenously into the donor before the operation, and added (1 mg/L) to the flush and preservation fluid, while PGE1 was replaced by normal saline in the control group.	Alprostadil	27-31	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
9886730-8	1998	Peak oxygen consumption (ml x min(-1) x kg(-1)) was significantly increased in both the training (16.8+/-4.9 to 25.3+/-6.9) and non-training groups (16.3+/-5.1 to 19.6+/-6.0) 3 months after percutaneous balloon mitral valvuloplasty.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	30-36
9845780-9	1998	The Ventolin Diskhaler using its own formulation operated at 60 l min-1 gave a FPF of 40.33%, but the FPF obtained was sensitive to flow, being only 25.65% of the nominal dose at 30 l min-1.	Albuterol	4-12	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
9845780-9	1998	The Ventolin Diskhaler using its own formulation operated at 60 l min-1 gave a FPF of 40.33%, but the FPF obtained was sensitive to flow, being only 25.65% of the nominal dose at 30 l min-1.	Albuterol	4-12	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
9879598-5	1998	Urine collagenase activity was higher in the group of patients than in the control group (8.59 +/- 4.26 pmol AMC/mg creatinine per min-1 vs control 3.84 +/- 2.09 pmol AMC/mg creatinine per min-1 P < 0.02).	7-amino-4-methylcoumarin	109-112	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
9879598-5	1998	Urine collagenase activity was higher in the group of patients than in the control group (8.59 +/- 4.26 pmol AMC/mg creatinine per min-1 vs control 3.84 +/- 2.09 pmol AMC/mg creatinine per min-1 P < 0.02).	Creatinine	116-126	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
9813086-4	1998	Jurkat T cells cultured in PUFA-supplemented medium showed a markedly diminished calcium response when stimulated via the transmembrane CD3 complex or glycosyl phosphatidylinositol (GPI)- anchored CD59.	Calcium	81-88	CD59 molecule (CD59 blood group)	Homo sapiens	197-201
10211013-2	1998	A single bolus infusion of remifentanil 10 micrograms kg-1 min-1 was given at the beginning of the dissection and anhepatic phases of OLT.	Remifentanil	27-39	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
10211013-4	1998	Mean arterial clearance of remifentanil was significantly greater (P = 0.02) in the dissection phase (79.54 ml min-1 kg-1) than in the anhepatic phase (39.57 ml min-1 kg-1).	Remifentanil	27-39	CD59 molecule (CD59 blood group)	Homo sapiens	111-121
10211013-4	1998	Mean arterial clearance of remifentanil was significantly greater (P = 0.02) in the dissection phase (79.54 ml min-1 kg-1) than in the anhepatic phase (39.57 ml min-1 kg-1).	Remifentanil	27-39	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
9834804-9	1998	CO2 elimination decreased in both groups from about 220 ml 70 kg-1 min-1 at the end of anaesthesia to a lowest value of about 160 ml 70 kg-1 min-1.	Carbon Dioxide	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
9834804-9	1998	CO2 elimination decreased in both groups from about 220 ml 70 kg-1 min-1 at the end of anaesthesia to a lowest value of about 160 ml 70 kg-1 min-1.	Carbon Dioxide	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
9813086-4	1998	Jurkat T cells cultured in PUFA-supplemented medium showed a markedly diminished calcium response when stimulated via the transmembrane CD3 complex or glycosyl phosphatidylinositol (GPI)- anchored CD59.	Glycosylphosphatidylinositols	151-180	CD59 molecule (CD59 blood group)	Homo sapiens	197-201
9813086-4	1998	Jurkat T cells cultured in PUFA-supplemented medium showed a markedly diminished calcium response when stimulated via the transmembrane CD3 complex or glycosyl phosphatidylinositol (GPI)- anchored CD59.	Glycosylphosphatidylinositols	182-185	CD59 molecule (CD59 blood group)	Homo sapiens	197-201
9806701-6	1998	The elimination rate constant from the peripheral compartment was fixed to the in vitro rate of degradation of cisatracurium in human plasma (0.0237 min(-1)).	cisatracurium	111-124	CD59 molecule (CD59 blood group)	Homo sapiens	149-155
9815028-6	1998	min-1) strongly and significantly inhibited hypoglycemia-induced antral motility, gastric acid secretion, pancreatic bicarbonate and protein secretion, and pancreatic polypeptide (PP) secretion.	Bicarbonates	117-128	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9833596-7	1998	Following the administration of the pure enantiomers CLO of (S)-propafenone increased (P= 0.007) to 2028+/-959 ml min(-1) and that of (R)-propafenone was reduced (P= 0.042) to 1318+/-867 ml min(-1).	clo	53-56	CD59 molecule (CD59 blood group)	Homo sapiens	114-120
9833596-7	1998	Following the administration of the pure enantiomers CLO of (S)-propafenone increased (P= 0.007) to 2028+/-959 ml min(-1) and that of (R)-propafenone was reduced (P= 0.042) to 1318+/-867 ml min(-1).	Propafenone	60-75	CD59 molecule (CD59 blood group)	Homo sapiens	114-120
9806701-7	1998	The mean terminal half-life of cisatracurium was 23.9+/-3.3 min, and its total clearance averaged 3.7+/-0.8 mL x min(-1) x kg(-1).	cisatracurium	31-44	CD59 molecule (CD59 blood group)	Homo sapiens	113-119
9818157-6	1998	Training increased (P < 0.05) the exercise FVC responses to ACH (0.3344 +/- 0.1208 vs. 0.4303 +/- 0.0858 units, before vs. after training, 60 micrograms min-1) and SNP (0.2066 +/- 0.0849 vs. 0.3172 +/- 0.0628 units, 6.4 micrograms min-1).	Acetylcholine	63-66	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
9842910-6	1998	Co-immunoprecipitation experiments with antibodies to the MAL molecule or to the GPI-anchored CD59 antigen indicated specific association of MAL with GPI-anchored proteins and Src-like tyrosine kinases.	Glycosylphosphatidylinositols	81-84	CD59 molecule (CD59 blood group)	Homo sapiens	94-98
9792917-5	1998	DBDH oxidized xenobiotic alicyclic alcohols and 3alpha- or 17beta-hydroxy-5beta-androstanes, and catalyzed the reversible conversion between prostaglandin D2 and 9alpha,11beta-prostaglandin F2 more efficiently than that of 3alpha- or 17beta-hydroxysteroids:the respective Km values were 0.6 and 6.8 microM, and kcat/Km values were about 1,000 min-1.mM-1.	Prostaglandin D2	141-157	CD59 molecule (CD59 blood group)	Homo sapiens	343-348
9792917-5	1998	DBDH oxidized xenobiotic alicyclic alcohols and 3alpha- or 17beta-hydroxy-5beta-androstanes, and catalyzed the reversible conversion between prostaglandin D2 and 9alpha,11beta-prostaglandin F2 more efficiently than that of 3alpha- or 17beta-hydroxysteroids:the respective Km values were 0.6 and 6.8 microM, and kcat/Km values were about 1,000 min-1.mM-1.	Triamcinolone Acetonide	162-168	CD59 molecule (CD59 blood group)	Homo sapiens	343-348
9792917-5	1998	DBDH oxidized xenobiotic alicyclic alcohols and 3alpha- or 17beta-hydroxy-5beta-androstanes, and catalyzed the reversible conversion between prostaglandin D2 and 9alpha,11beta-prostaglandin F2 more efficiently than that of 3alpha- or 17beta-hydroxysteroids:the respective Km values were 0.6 and 6.8 microM, and kcat/Km values were about 1,000 min-1.mM-1.	11beta-PGF2alpha	169-192	CD59 molecule (CD59 blood group)	Homo sapiens	343-348
9792917-5	1998	DBDH oxidized xenobiotic alicyclic alcohols and 3alpha- or 17beta-hydroxy-5beta-androstanes, and catalyzed the reversible conversion between prostaglandin D2 and 9alpha,11beta-prostaglandin F2 more efficiently than that of 3alpha- or 17beta-hydroxysteroids:the respective Km values were 0.6 and 6.8 microM, and kcat/Km values were about 1,000 min-1.mM-1.	3alpha- or 17beta-hydroxysteroids	223-256	CD59 molecule (CD59 blood group)	Homo sapiens	343-348
9818157-6	1998	Training increased (P < 0.05) the exercise FVC responses to ACH (0.3344 +/- 0.1208 vs. 0.4303 +/- 0.0858 units, before vs. after training, 60 micrograms min-1) and SNP (0.2066 +/- 0.0849 vs. 0.3172 +/- 0.0628 units, 6.4 micrograms min-1).	Acetylcholine	63-66	CD59 molecule (CD59 blood group)	Homo sapiens	234-239
10518920-10	1998	cm-2.min-1/degree C. The results of this study clearly demonstrated the temperature-dependency of flux rates of water across vaginal mucosa, and this should be taken into account whenever the in vitro vaginal/buccal model is used at room temperature for predicting in vivo buccal drug absorption kinetics.	Water	112-117	CD59 molecule (CD59 blood group)	Homo sapiens	5-10
9755482-1	1998	Washed human erythrocytes incubated with glucose and S8 and purged with N2 produced H2S at a nearly constant rate of 170 mumol (L cells)-1 min-1, which continued for several hours.	Glucose	41-48	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
9761744-5	1998	From endothelial cells, MBCD released GPI-anchored CD59, and CD44, but only a negligible amount of caveolin.	Glycosylphosphatidylinositols	38-41	CD59 molecule (CD59 blood group)	Homo sapiens	51-55
9755482-1	1998	Washed human erythrocytes incubated with glucose and S8 and purged with N2 produced H2S at a nearly constant rate of 170 mumol (L cells)-1 min-1, which continued for several hours.	Nitrogen	72-74	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
9755482-1	1998	Washed human erythrocytes incubated with glucose and S8 and purged with N2 produced H2S at a nearly constant rate of 170 mumol (L cells)-1 min-1, which continued for several hours.	Hydrogen Sulfide	84-87	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
9781626-4	1998	Systemic and hepatic glutamine gluconeogenesis increased from 0.45 +/- 0.3 and 0.11 +/- 0.02 micromol x kg(-1) x min(-1), respectively, to 0.61 +/- 0.04 (P = .002) and 0.31 +/- 0.03 micromol x kg(-1) x min(-1) (P = .001), respectively, whereas renal glutamine gluconeogenesis was unchanged (from 0.33 +/- 0.03 to 0.30 +/- 0.04 micromol x kg(-1) x min(-1), P = .20).	Glutamine	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	113-119
9773721-8	1998	In the control subjects, HGP increased by 10.7+/-4.2 micromol x kg(-1) x min(-1) under glucagon infusion.	Glucagon	87-95	CD59 molecule (CD59 blood group)	Homo sapiens	73-79
9760344-10	1998	The net effect of MM -40 was a 33% reduction in SV index (from 27 to 18 ml/min2), and a 21% reduction in SBP (from 121 to 96 mmHg).	mm -40	18-24	CD59 molecule (CD59 blood group)	Homo sapiens	75-79
9781626-4	1998	Systemic and hepatic glutamine gluconeogenesis increased from 0.45 +/- 0.3 and 0.11 +/- 0.02 micromol x kg(-1) x min(-1), respectively, to 0.61 +/- 0.04 (P = .002) and 0.31 +/- 0.03 micromol x kg(-1) x min(-1) (P = .001), respectively, whereas renal glutamine gluconeogenesis was unchanged (from 0.33 +/- 0.03 to 0.30 +/- 0.04 micromol x kg(-1) x min(-1), P = .20).	Glutamine	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	202-208
9781626-4	1998	Systemic and hepatic glutamine gluconeogenesis increased from 0.45 +/- 0.3 and 0.11 +/- 0.02 micromol x kg(-1) x min(-1), respectively, to 0.61 +/- 0.04 (P = .002) and 0.31 +/- 0.03 micromol x kg(-1) x min(-1) (P = .001), respectively, whereas renal glutamine gluconeogenesis was unchanged (from 0.33 +/- 0.03 to 0.30 +/- 0.04 micromol x kg(-1) x min(-1), P = .20).	Glutamine	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	202-208
9847642-15	1998	The simulated constant infusion rate for remifentanil of 15 micrograms.min1 (8 micrograms.min-1 for fentanyl and 75 micrograms.min-1 for alfentanil) allowed the therapeutic threshold to be reached in 10 min with remifentanil, in 22 min with fentanyl and in 17 min with alfentanil.	Remifentanil	41-53	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
9871930-8	1998	Cardiac output values in L.min-1 (mean +/- SD) were as follows: C, 4.99 +/- 0.39; FiO2, 5.44 +/- 0.86; FiIG, 5.55 +/- 0.92; TH, 5.77 +/- 0.88; and E, 5.53 +/- 0.64.	Carbon	0-1	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
9847642-15	1998	The simulated constant infusion rate for remifentanil of 15 micrograms.min1 (8 micrograms.min-1 for fentanyl and 75 micrograms.min-1 for alfentanil) allowed the therapeutic threshold to be reached in 10 min with remifentanil, in 22 min with fentanyl and in 17 min with alfentanil.	Remifentanil	41-53	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
9847642-15	1998	The simulated constant infusion rate for remifentanil of 15 micrograms.min1 (8 micrograms.min-1 for fentanyl and 75 micrograms.min-1 for alfentanil) allowed the therapeutic threshold to be reached in 10 min with remifentanil, in 22 min with fentanyl and in 17 min with alfentanil.	Fentanyl	100-108	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
9847642-15	1998	The simulated constant infusion rate for remifentanil of 15 micrograms.min1 (8 micrograms.min-1 for fentanyl and 75 micrograms.min-1 for alfentanil) allowed the therapeutic threshold to be reached in 10 min with remifentanil, in 22 min with fentanyl and in 17 min with alfentanil.	Alfentanil	137-147	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
9847642-15	1998	The simulated constant infusion rate for remifentanil of 15 micrograms.min1 (8 micrograms.min-1 for fentanyl and 75 micrograms.min-1 for alfentanil) allowed the therapeutic threshold to be reached in 10 min with remifentanil, in 22 min with fentanyl and in 17 min with alfentanil.	Remifentanil	212-224	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
9847642-15	1998	The simulated constant infusion rate for remifentanil of 15 micrograms.min1 (8 micrograms.min-1 for fentanyl and 75 micrograms.min-1 for alfentanil) allowed the therapeutic threshold to be reached in 10 min with remifentanil, in 22 min with fentanyl and in 17 min with alfentanil.	Fentanyl	241-249	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
9847642-15	1998	The simulated constant infusion rate for remifentanil of 15 micrograms.min1 (8 micrograms.min-1 for fentanyl and 75 micrograms.min-1 for alfentanil) allowed the therapeutic threshold to be reached in 10 min with remifentanil, in 22 min with fentanyl and in 17 min with alfentanil.	Alfentanil	269-279	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
9751677-8	1998	min-1 adenosine as normal (flow >/=2 mL .	Adenosine	6-15	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9737993-1	1998	CD59 is a glycosylphosphatidylinositol-anchored cell surface glycoprotein involved in protecting cells from host-mediated complement attack.	Glycosylphosphatidylinositols	10-38	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
9737993-4	1998	Antibody-induced cross-linking of CD59 on the surface of THP-1 and U937 hematopoietic cell lines as well as exposure to complement 8 induces a rapid increase in the tyrosine phosphorylation of several proteins within the cell.	Tyrosine	165-173	CD59 molecule (CD59 blood group)	Homo sapiens	34-38
9724254-6	1998	min-1), Na+-dependent mechanism that was inhibited by chlorimipramine > imipramine > fluoxetine > desipramine > zimelidine.	Clomipramine	54-69	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9748347-8	1998	Loaded VAChT reorients quickly (73 000 min-1) and releases ACh to the inside (KAChi = 44 000 mM) and the proton to the outside.	Acetylcholine	8-11	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
9748494-4	1998	Turnover numbers were of the order of 5000-12000 min-1 for the wild-type enzyme and the D70G and D70K enzymes in 100 mM Tris, pH 7.4, containing 50 mM CaCl2 at 25 degreesC; Km values were 6 mM for wild-type, 16 mM for D70G and 38 mM for D70K.	Tromethamine	120-124	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
9748494-13	1998	The bimolecular rate constants for hydrolysis of aspirin by wild-type, D70G and D70K enzymes were found to be close to 1x106 M-1 min-1.	Aspirin	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
9777029-3	1998	In response to the higher work intensities, ventilations (VE) of 129 +/- 10 and 155 +/- 8 L min-1 enhanced the end tidal PO2 (PETO2) to the same extent (117 +/- 2 mmHg), but PaO2 became reduced (from 102 +/- 2 to 78 +/- 2 and 81 +/- 3 mmHg, respectively).	po2	121-124	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
9777029-3	1998	In response to the higher work intensities, ventilations (VE) of 129 +/- 10 and 155 +/- 8 L min-1 enhanced the end tidal PO2 (PETO2) to the same extent (117 +/- 2 mmHg), but PaO2 became reduced (from 102 +/- 2 to 78 +/- 2 and 81 +/- 3 mmHg, respectively).	peto2	126-131	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
9777029-3	1998	In response to the higher work intensities, ventilations (VE) of 129 +/- 10 and 155 +/- 8 L min-1 enhanced the end tidal PO2 (PETO2) to the same extent (117 +/- 2 mmHg), but PaO2 became reduced (from 102 +/- 2 to 78 +/- 2 and 81 +/- 3 mmHg, respectively).	pao2	174-178	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
9724254-6	1998	min-1), Na+-dependent mechanism that was inhibited by chlorimipramine > imipramine > fluoxetine > desipramine > zimelidine.	Imipramine	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9724254-6	1998	min-1), Na+-dependent mechanism that was inhibited by chlorimipramine > imipramine > fluoxetine > desipramine > zimelidine.	Fluoxetine	91-101	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9724254-6	1998	min-1), Na+-dependent mechanism that was inhibited by chlorimipramine > imipramine > fluoxetine > desipramine > zimelidine.	Desipramine	107-118	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9724254-6	1998	min-1), Na+-dependent mechanism that was inhibited by chlorimipramine > imipramine > fluoxetine > desipramine > zimelidine.	Zimeldine	124-134	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9743396-7	1998	Alfentanil decreased both the initial and second acute hypoxic responses (from 1.27+/-0.73 to 0.99+/-0.39 l x min(-1) x %(-1), P < 0.05; and from 0.99+/-0.70 to 0.41+/-0.29 l x min(-1) x %(-1), P < 0.05, respectively).	Alfentanil	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	110-116
9743396-7	1998	Alfentanil decreased both the initial and second acute hypoxic responses (from 1.27+/-0.73 to 0.99+/-0.39 l x min(-1) x %(-1), P < 0.05; and from 0.99+/-0.70 to 0.41+/-0.29 l x min(-1) x %(-1), P < 0.05, respectively).	Alfentanil	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	180-186
9743400-5	1998	RESULTS: The slope of the ventilatory response to carbon dioxide decreased from 1.08+/-0.38 to 0.79+/-0.36 l x min(-1) x mmHg(-1) (x +/- SD, P < 0.05) during alfentanil infusion; after diphenhydramine, the slope increased to 1.17+/-0.28 l x min(-1) x mmHg(-1) (P < 0.05).	Carbon Dioxide	50-64	CD59 molecule (CD59 blood group)	Homo sapiens	111-117
9743400-5	1998	RESULTS: The slope of the ventilatory response to carbon dioxide decreased from 1.08+/-0.38 to 0.79+/-0.36 l x min(-1) x mmHg(-1) (x +/- SD, P < 0.05) during alfentanil infusion; after diphenhydramine, the slope increased to 1.17+/-0.28 l x min(-1) x mmHg(-1) (P < 0.05).	Carbon Dioxide	50-64	CD59 molecule (CD59 blood group)	Homo sapiens	244-250
9762405-2	1998	The values are estimated as the initial velocity (V) expressed in eta 14CO2 x min-1 x g-1 of fresh tissues by [U-14C] glucose metabolism.	Glucose	118-125	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
9861115-4	1998	The rate of decline in oxygen tension (31 (95% confidence interval (CI) 20.1-42.2) mm Hg min-1) was more than three times that reported in studies in adults.	Oxygen	23-29	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
9861115-5	1998	The rate of increase in carbon dioxide tension (4.2 (95% CI 3.7-4.7) mm Hg min-1) was similar to that reported in adults.	Carbon Dioxide	24-38	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
9754970-6	1998	Mean post-absorptive glucose oxidation rose from 126 (SEM 15) mg x min(-1) (day 0) to 164 (SEM 14) mg x min(-1) (day 8, P = 0.04) and 160 (SEM 20) mg x min(-1) (day 40, P = 0.07).	Glucose	21-28	CD59 molecule (CD59 blood group)	Homo sapiens	67-73
9849279-4	1998	The rate of uptake was equivalent to 059e-0.32t + 0.039e-0.036t + 0.105e-0.0034t ml.min-1 liquid sevoflurane.	Sevoflurane	97-108	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
9754970-6	1998	Mean post-absorptive glucose oxidation rose from 126 (SEM 15) mg x min(-1) (day 0) to 164 (SEM 14) mg x min(-1) (day 8, P = 0.04) and 160 (SEM 20) mg x min(-1) (day 40, P = 0.07).	Glucose	21-28	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
9767368-5	1998	RESULTS: Digoxin treatment significantly decreased heart rate (HR) and diastolic blood pressure (DBP) during the overnight sleeping phase of day 10 compared with placebo (HR, 4 beats min-1; DBP, 8 mmHg; P < 0.05).	Digoxin	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
9754970-6	1998	Mean post-absorptive glucose oxidation rose from 126 (SEM 15) mg x min(-1) (day 0) to 164 (SEM 14) mg x min(-1) (day 8, P = 0.04) and 160 (SEM 20) mg x min(-1) (day 40, P = 0.07).	Glucose	21-28	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
9767368-6	1998	Digitoxin treatment significantly decreased heart rate and diastolic blood pressure during the overnight sleeping phase of day 4 (HR, 8 beats min-1; DBP, 7 mmHg) and day 10 (HR, 7 beats min-1; DBP, 5 mmHg) compared with placebo (P < 0.05).	Digitoxin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
9833322-6	1998	Especially, the complex containing 13-membered chelator is an artificial metalloesterase with catalytic rate constant kcat = 3.8 x 10(-3) min-1 and Michaelis constant K(m) = 3.5 x 10(-4) M for the hydrolysis of p-nitrophenyl adamantate via metal-hydroxide mechanism.	p-nitrophenyl adamantate	211-235	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
9767368-6	1998	Digitoxin treatment significantly decreased heart rate and diastolic blood pressure during the overnight sleeping phase of day 4 (HR, 8 beats min-1; DBP, 7 mmHg) and day 10 (HR, 7 beats min-1; DBP, 5 mmHg) compared with placebo (P < 0.05).	Digitoxin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
9833322-6	1998	Especially, the complex containing 13-membered chelator is an artificial metalloesterase with catalytic rate constant kcat = 3.8 x 10(-3) min-1 and Michaelis constant K(m) = 3.5 x 10(-4) M for the hydrolysis of p-nitrophenyl adamantate via metal-hydroxide mechanism.	metal-hydroxide	240-255	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
10071392-2	1998	Highly sensitive detection for nM to microM order of uric acid was achieved when 10 mM TRIS-HCl buffer (pH 10.0) containing 20 mM DTT was used as a carrier at 0.6 ml min-1 and 37 degrees C. The sensitivity of the uric acid was much improved over a batch method using a uricase membrane-coupling electrode, and the detection limit (ca.	Uric Acid	53-62	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
10071392-2	1998	Highly sensitive detection for nM to microM order of uric acid was achieved when 10 mM TRIS-HCl buffer (pH 10.0) containing 20 mM DTT was used as a carrier at 0.6 ml min-1 and 37 degrees C. The sensitivity of the uric acid was much improved over a batch method using a uricase membrane-coupling electrode, and the detection limit (ca.	Tris hydrochloride	87-95	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
9705755-7	1998	Approximately 20% of the human samples were as active in N-oxidation and conversion of MeIQx to bacterial mutagens as microsomes of PCB-pretreated rats [3-4 nmol of NHOH-MeIQx formed min-1 (mg of protein)-1].	Polychlorinated Biphenyls	132-135	CD59 molecule (CD59 blood group)	Homo sapiens	183-206
9721005-7	1998	Following repeated immersions in water at 15 degrees C, the fR, VI and fH responses of the H group over the first 30 s of immersion were reduced (P < 0.01) from 33.3 breaths x min(-1), 50.5 l x min(-1) and 114 beats x min(-1) respectively, to 19.8 breaths x min(-1) 26.41 x min(-1) and 98 beats x min(-1), respectively.	Water	33-38	CD59 molecule (CD59 blood group)	Homo sapiens	179-185
9721005-7	1998	Following repeated immersions in water at 15 degrees C, the fR, VI and fH responses of the H group over the first 30 s of immersion were reduced (P < 0.01) from 33.3 breaths x min(-1), 50.5 l x min(-1) and 114 beats x min(-1) respectively, to 19.8 breaths x min(-1) 26.41 x min(-1) and 98 beats x min(-1), respectively.	Water	33-38	CD59 molecule (CD59 blood group)	Homo sapiens	197-203
9721005-7	1998	Following repeated immersions in water at 15 degrees C, the fR, VI and fH responses of the H group over the first 30 s of immersion were reduced (P < 0.01) from 33.3 breaths x min(-1), 50.5 l x min(-1) and 114 beats x min(-1) respectively, to 19.8 breaths x min(-1) 26.41 x min(-1) and 98 beats x min(-1), respectively.	Water	33-38	CD59 molecule (CD59 blood group)	Homo sapiens	197-203
9721005-7	1998	Following repeated immersions in water at 15 degrees C, the fR, VI and fH responses of the H group over the first 30 s of immersion were reduced (P < 0.01) from 33.3 breaths x min(-1), 50.5 l x min(-1) and 114 beats x min(-1) respectively, to 19.8 breaths x min(-1) 26.41 x min(-1) and 98 beats x min(-1), respectively.	Water	33-38	CD59 molecule (CD59 blood group)	Homo sapiens	197-203
9721005-7	1998	Following repeated immersions in water at 15 degrees C, the fR, VI and fH responses of the H group over the first 30 s of immersion were reduced (P < 0.01) from 33.3 breaths x min(-1), 50.5 l x min(-1) and 114 beats x min(-1) respectively, to 19.8 breaths x min(-1) 26.41 x min(-1) and 98 beats x min(-1), respectively.	Water	33-38	CD59 molecule (CD59 blood group)	Homo sapiens	197-203
9721005-7	1998	Following repeated immersions in water at 15 degrees C, the fR, VI and fH responses of the H group over the first 30 s of immersion were reduced (P < 0.01) from 33.3 breaths x min(-1), 50.5 l x min(-1) and 114 beats x min(-1) respectively, to 19.8 breaths x min(-1) 26.41 x min(-1) and 98 beats x min(-1), respectively.	Water	33-38	CD59 molecule (CD59 blood group)	Homo sapiens	197-203
9721005-8	1998	In water at 10 degrees C these responses were reduced (P < 0.01) from 47.3 breaths x min(-1), 67.61 x min(-1) and 128 beats x min(-1) to 24.0 breaths x min(-1), 29.5 l x min(-1) and 109 beats x min(-1), respectively over a corresponding period of immersion.	Water	3-8	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
9721005-8	1998	In water at 10 degrees C these responses were reduced (P < 0.01) from 47.3 breaths x min(-1), 67.61 x min(-1) and 128 beats x min(-1) to 24.0 breaths x min(-1), 29.5 l x min(-1) and 109 beats x min(-1), respectively over a corresponding period of immersion.	Water	3-8	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
9721005-8	1998	In water at 10 degrees C these responses were reduced (P < 0.01) from 47.3 breaths x min(-1), 67.61 x min(-1) and 128 beats x min(-1) to 24.0 breaths x min(-1), 29.5 l x min(-1) and 109 beats x min(-1), respectively over a corresponding period of immersion.	Water	3-8	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
9721005-8	1998	In water at 10 degrees C these responses were reduced (P < 0.01) from 47.3 breaths x min(-1), 67.61 x min(-1) and 128 beats x min(-1) to 24.0 breaths x min(-1), 29.5 l x min(-1) and 109 beats x min(-1), respectively over a corresponding period of immersion.	Water	3-8	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
9721005-8	1998	In water at 10 degrees C these responses were reduced (P < 0.01) from 47.3 breaths x min(-1), 67.61 x min(-1) and 128 beats x min(-1) to 24.0 breaths x min(-1), 29.5 l x min(-1) and 109 beats x min(-1), respectively over a corresponding period of immersion.	Water	3-8	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
9721005-8	1998	In water at 10 degrees C these responses were reduced (P < 0.01) from 47.3 breaths x min(-1), 67.61 x min(-1) and 128 beats x min(-1) to 24.0 breaths x min(-1), 29.5 l x min(-1) and 109 beats x min(-1), respectively over a corresponding period of immersion.	Water	3-8	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
9757923-6	1998	Systemic clearance of propofol was much higher than liver blood flow with average values on the six observation days ranging from 74.0 to 81.2 ml x min(-1) x kg(-1) and was not affected by switching from parenteral to enteral feeding.	Propofol	22-30	CD59 molecule (CD59 blood group)	Homo sapiens	148-154
9705755-7	1998	Approximately 20% of the human samples were as active in N-oxidation and conversion of MeIQx to bacterial mutagens as microsomes of PCB-pretreated rats [3-4 nmol of NHOH-MeIQx formed min-1 (mg of protein)-1].	nhoh-meiqx	165-175	CD59 molecule (CD59 blood group)	Homo sapiens	183-206
9705755-8	1998	In contrast, microsomes from PCB-treated rats displayed higher rates of PhIP N-oxidation and activation to mutagens than the most active human liver microsomes [8-24 vs 2-4 nmol of HNOH-PhIP formed min-1 (mg of protein)-1].	Polychlorinated Biphenyls	29-32	CD59 molecule (CD59 blood group)	Homo sapiens	198-221
9705755-8	1998	In contrast, microsomes from PCB-treated rats displayed higher rates of PhIP N-oxidation and activation to mutagens than the most active human liver microsomes [8-24 vs 2-4 nmol of HNOH-PhIP formed min-1 (mg of protein)-1].	hnoh	181-185	CD59 molecule (CD59 blood group)	Homo sapiens	198-221
9711998-5	1998	In the same subjects, GSH infusion significantly increased total glucose uptake (from 37.1 +/- 6.7 micromol kg(-1) x min(-1) to 39.5 +/- 7.7 micromol x kg(-1) x min(-1), P < .05), whereas saline infusion was completely ineffective.	Glutathione	22-25	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
9711998-5	1998	In the same subjects, GSH infusion significantly increased total glucose uptake (from 37.1 +/- 6.7 micromol kg(-1) x min(-1) to 39.5 +/- 7.7 micromol x kg(-1) x min(-1), P < .05), whereas saline infusion was completely ineffective.	Glutathione	22-25	CD59 molecule (CD59 blood group)	Homo sapiens	161-167
9711998-5	1998	In the same subjects, GSH infusion significantly increased total glucose uptake (from 37.1 +/- 6.7 micromol kg(-1) x min(-1) to 39.5 +/- 7.7 micromol x kg(-1) x min(-1), P < .05), whereas saline infusion was completely ineffective.	Glucose	65-72	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
9711998-7	1998	Similar findings were found in diabetic patients, in whom GSH infusion significantly increased both total glucose uptake (from 25.3 +/- 9.0 micromol x kg(-1) x min(-1) to 31.4 +/- 10.0 micromol x kg(-1) x min(-1), P < .001) and intraerythrocytic GSH/GSSG ratio (from 14.8 +/- 4.1 to 21.7 +/- 6.7, P < .01).	Glutathione	58-61	CD59 molecule (CD59 blood group)	Homo sapiens	160-166
9711998-7	1998	Similar findings were found in diabetic patients, in whom GSH infusion significantly increased both total glucose uptake (from 25.3 +/- 9.0 micromol x kg(-1) x min(-1) to 31.4 +/- 10.0 micromol x kg(-1) x min(-1), P < .001) and intraerythrocytic GSH/GSSG ratio (from 14.8 +/- 4.1 to 21.7 +/- 6.7, P < .01).	Glutathione	58-61	CD59 molecule (CD59 blood group)	Homo sapiens	205-211
9711998-7	1998	Similar findings were found in diabetic patients, in whom GSH infusion significantly increased both total glucose uptake (from 25.3 +/- 9.0 micromol x kg(-1) x min(-1) to 31.4 +/- 10.0 micromol x kg(-1) x min(-1), P < .001) and intraerythrocytic GSH/GSSG ratio (from 14.8 +/- 4.1 to 21.7 +/- 6.7, P < .01).	Glucose	106-113	CD59 molecule (CD59 blood group)	Homo sapiens	160-166
18967229-4	1998	Using a column packed with 0.25 ml of a sorbent and a sample volume of 100 ml, Cu(2+) is quantitatively accumulated from all of the matrices studied even at a capacity of 6 mumol ml(-1) of adsorbent and a flow rate as high as 100 ml min(-1).	cupric ion	79-85	CD59 molecule (CD59 blood group)	Homo sapiens	233-239
9715738-6	1998	During the same period, oxygen uptake increased from 1.30 +/- 0.15 to 2.40 +/- 0.23 L min-1, which partially compensated for the decreased anaerobic metabolism.	Oxygen	24-30	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
9682151-4	1998	The retention time L-768673 was approximately 28 min with a flow rate of 1.5 ml min-1.	L 768673	19-27	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
9671976-3	1998	Replacing NaCl in the hyposmotic medium by sugars and polyalcohols markedly accelerated RVD increasing k to 0.37-0.39 min(-1) and full recovery in 3-5 min.	Sodium Chloride	10-14	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
9671976-3	1998	Replacing NaCl in the hyposmotic medium by sugars and polyalcohols markedly accelerated RVD increasing k to 0.37-0.39 min(-1) and full recovery in 3-5 min.	Sugars	43-49	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
9671976-3	1998	Replacing NaCl in the hyposmotic medium by sugars and polyalcohols markedly accelerated RVD increasing k to 0.37-0.39 min(-1) and full recovery in 3-5 min.	polyalcohols	54-66	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
9671976-6	1998	Replacing Na by other cations or Cl by gluconate increased k to 0.22 min(-1) and 0.26 min(-1), respectively, and 86Rb efflux by 4-23% and 39, respectively.	gluconic acid	39-48	CD59 molecule (CD59 blood group)	Homo sapiens	69-75
9671976-6	1998	Replacing Na by other cations or Cl by gluconate increased k to 0.22 min(-1) and 0.26 min(-1), respectively, and 86Rb efflux by 4-23% and 39, respectively.	gluconic acid	39-48	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
9669788-11	1998	However, the total and nonrenal clearances of cotinine were significantly lower, respectively, in blacks (0.56 and 0.47 mL x min(-1) x kg(-1)) than in whites (0.68 vs 0.61 mL x min(-1) x kg(-1); P=.009 for each comparison).	Cotinine	46-54	CD59 molecule (CD59 blood group)	Homo sapiens	125-131
9669788-11	1998	However, the total and nonrenal clearances of cotinine were significantly lower, respectively, in blacks (0.56 and 0.47 mL x min(-1) x kg(-1)) than in whites (0.68 vs 0.61 mL x min(-1) x kg(-1); P=.009 for each comparison).	Cotinine	46-54	CD59 molecule (CD59 blood group)	Homo sapiens	177-183
9695722-2	1998	METHODS: Twelve healthy subjects received a short-term infusion (90 minutes) of urodilatin and placebo with a graded infusion rate (from 7.5 to 15 to 30 ng.kg body weight-1.min-1) in a randomized, double-blind, crossover study design.	Ularitide	80-90	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
9661575-6	1998	Postoperative analgesia was achieved with fentanyl (0.5 microgram/kg) and evaluated using the pain visual analog scale for 4 h. During the intraoperative and postoperative periods, patients in the magnesium group required significantly less fentanyl than those in the control group (control group 0.089 +/- 0.02 microgram.kg-1.min-1 versus magnesium group 0.058 +/- 0.01 microgram.kg-1.min-1; P < 0.05 and control group 0.021 +/- 0.013 microgram.kg-1.min-1 and magnesium group 0.0031 +/- 0.0018 microgram.kg-1.min-1; P < 0.01 for intraoperative and postoperative periods, respectively).	Magnesium	197-206	CD59 molecule (CD59 blood group)	Homo sapiens	327-332
9661575-6	1998	Postoperative analgesia was achieved with fentanyl (0.5 microgram/kg) and evaluated using the pain visual analog scale for 4 h. During the intraoperative and postoperative periods, patients in the magnesium group required significantly less fentanyl than those in the control group (control group 0.089 +/- 0.02 microgram.kg-1.min-1 versus magnesium group 0.058 +/- 0.01 microgram.kg-1.min-1; P < 0.05 and control group 0.021 +/- 0.013 microgram.kg-1.min-1 and magnesium group 0.0031 +/- 0.0018 microgram.kg-1.min-1; P < 0.01 for intraoperative and postoperative periods, respectively).	Magnesium	197-206	CD59 molecule (CD59 blood group)	Homo sapiens	386-391
9661575-6	1998	Postoperative analgesia was achieved with fentanyl (0.5 microgram/kg) and evaluated using the pain visual analog scale for 4 h. During the intraoperative and postoperative periods, patients in the magnesium group required significantly less fentanyl than those in the control group (control group 0.089 +/- 0.02 microgram.kg-1.min-1 versus magnesium group 0.058 +/- 0.01 microgram.kg-1.min-1; P < 0.05 and control group 0.021 +/- 0.013 microgram.kg-1.min-1 and magnesium group 0.0031 +/- 0.0018 microgram.kg-1.min-1; P < 0.01 for intraoperative and postoperative periods, respectively).	Magnesium	197-206	CD59 molecule (CD59 blood group)	Homo sapiens	386-391
9661575-6	1998	Postoperative analgesia was achieved with fentanyl (0.5 microgram/kg) and evaluated using the pain visual analog scale for 4 h. During the intraoperative and postoperative periods, patients in the magnesium group required significantly less fentanyl than those in the control group (control group 0.089 +/- 0.02 microgram.kg-1.min-1 versus magnesium group 0.058 +/- 0.01 microgram.kg-1.min-1; P < 0.05 and control group 0.021 +/- 0.013 microgram.kg-1.min-1 and magnesium group 0.0031 +/- 0.0018 microgram.kg-1.min-1; P < 0.01 for intraoperative and postoperative periods, respectively).	Magnesium	197-206	CD59 molecule (CD59 blood group)	Homo sapiens	386-391
9795066-2	1998	From the association constant of 18.9 x 10(5)l mol-1 min-1 and the dissociation constant of 25.0 x 10(-4) min-1 resulted the equilibrium dissociation constant KD of 1.32 nmol/l and a relative receptor affinity of 855 with dexamethasone as reference (100).	Dexamethasone	222-235	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
9795066-2	1998	From the association constant of 18.9 x 10(5)l mol-1 min-1 and the dissociation constant of 25.0 x 10(-4) min-1 resulted the equilibrium dissociation constant KD of 1.32 nmol/l and a relative receptor affinity of 855 with dexamethasone as reference (100).	Dexamethasone	222-235	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
9660486-9	1998	However, GSH uptake was significantly lower in Na+-free medium compared with Na+-containing medium (10.3+/-0.7 versus 16.8+/-0.9 picomoles/min(-1) per 10(6) cells; P < 0.01).	Glutathione	9-12	CD59 molecule (CD59 blood group)	Homo sapiens	139-145
9661121-1	1998	BACKGROUND: During periods in which nutrition support of critically ill young children must be parenteral, glucose infusions are administered at up to 10 or more mg.kg-1.min-1 to meet predicted energy needs.	Glucose	107-114	CD59 molecule (CD59 blood group)	Homo sapiens	170-175
9661121-9	1998	Although there was a significantly increased level of total glucose oxidation (3.2 to 3.8 mg.kg-1.min-1), this increment (29% +/- 9%) was accompanied by a significant decrease in the efficiency of energy production, because the bulk of the additional glucose above 5 mg.kg-1.min-1 was not being oxidized.	Glucose	60-67	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
9661121-11	1998	CONCLUSIONS: Maximum glucose oxidation in severely burned children occurs at intakes approximating 5 mg.kg-1.min-1.	Glucose	21-28	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
9768373-3	1998	The glucose infusion rate (GIR) was determined by glucose clamp procedure at an insulin infusion rate of 40 mU m-2 min-1 (plasma insulin concentrations: 700-800 pmol l-1).	Glucose	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
9637638-3	1998	METHODS: Nineteen parturients underwent nonemergent cesarean section with epidural anesthesia and received 0.1 microg kg(-1) x min(-1) remifentanil intravenously, which was continued until skin closure.	Remifentanil	135-147	CD59 molecule (CD59 blood group)	Homo sapiens	127-133
9637639-4	1998	Simultaneous with subarachnoid injection, infusion of angiotensin II (2.5 microg/ml) or ephedrine (5 mg/ml) was initiated at 10 ng x kg(-1) x min(-1) and 50 microg x kg(-1) x min(-1), respectively.	Ephedrine	88-97	CD59 molecule (CD59 blood group)	Homo sapiens	142-148
9689393-12	1998	Only Pancuronium caused a significant increase in heart rate (53 +/- 11 to 61 +/- 15 min-1) whereas cardiac index and mean arterial pressure did not change significantly.	Pancuronium	5-16	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
9771297-1	1998	We studied effects on the EEG of propofol infused at a rate of 0.5 mg kg-1 min-1 for 10 min in 10 healthy male surgical patients under extradural analgesia.	Propofol	33-41	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
9657560-7	1998	Differences (least square mean) between the pooled 10 and 50 mg montelukast treatment groups and placebo were: 7.1% change from baseline in FEV1, 19.23 L x min(-1) in morning PEFR, -0.29 in daytime asthma symptom score (absolute value), and -0.82 in beta2-agonist use (puff x day(-1)).	montelukast	64-75	CD59 molecule (CD59 blood group)	Homo sapiens	156-162
9850359-6	1998	The mean changes from baseline in morning PEF at weeks 5-6 were 47.0 l min-1 in the combined HFA-BDP group and 16.5 l min-1 in the HFA-placebo group.	hfa	131-134	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
10099275-4	1998	Denitrification conditions were successfully used for the reduction of 60 ppmv nitric oxide to 15 ppmv at a flow rate of 3 L min-1 (EBRT of 3 min) in a fully aerated, 17% v/v O2 (superficially aerobic) biofilter.	Nitric Oxide	79-91	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
9621448-7	1998	The apparent K(m) and Vmax values for dehalogenation of 1,3-DCP and 3-CPD were 0.105 mM and 223 mumol min-1 mg-1; and 2.366 mM and 1.742 mumol min-1 mg-1, respectively.	alpha-Chlorohydrin	68-73	CD59 molecule (CD59 blood group)	Homo sapiens	102-112
9621448-7	1998	The apparent K(m) and Vmax values for dehalogenation of 1,3-DCP and 3-CPD were 0.105 mM and 223 mumol min-1 mg-1; and 2.366 mM and 1.742 mumol min-1 mg-1, respectively.	alpha-Chlorohydrin	68-73	CD59 molecule (CD59 blood group)	Homo sapiens	143-153
9605061-2	1998	Ergotamine produced a 27% reduction in hyperemic MBF (2.62 +/- 0.11 vs 3.72 +/- 1.05 ml x min(-1) x g(-1); p <0.05), a 31% reduction in the coronary vasodilator reserve (1.81 +/- 0.50 vs 2.71 +/- 1.15; p <0.01), and a 55% increase in minimal coronary resistance (42.2 +/- 15 vs 26.7 +/- 8 mm Hg x min x ml(-1) x g(-1); p <0.001), suggesting vasoconstriction of the coronary microcirculation.	Ergotamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
9643619-6	1998	Somatostatin and octreotide elicit an indistinguishable hepatic blood flow decrease from 1.49 to 1.07 l min(-1).	Octreotide	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
9643620-8	1998	A similar renal clearance of bambuterol was found during oral administration but that of terbutaline decreased (to about 120 ml min(-1)).	Terbutaline	89-100	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
9628275-9	1998	Troglitazone improved whole-body glucose uptake (to 31.9+/-3.3 micromol x kg(-1) x min(-1) , p=0.028), and forearm glucose uptake (from 1.09+/-0.54 to 2.31+/-0.69 micromol dL(-1) x min(-1), p=0.006).	Troglitazone	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	83-89
9628275-9	1998	Troglitazone improved whole-body glucose uptake (to 31.9+/-3.3 micromol x kg(-1) x min(-1) , p=0.028), and forearm glucose uptake (from 1.09+/-0.54 to 2.31+/-0.69 micromol dL(-1) x min(-1), p=0.006).	Troglitazone	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	181-187
9787766-3	1998	At pH 7.4 and 25 degrees C, the major and minor components of the E3 isozyme catalyzed the reaction with Vmax of 1.1 and 0.8 mumol NADH min-1 mg-1 protein, respectively, compared to 0.067 and 0.060 mumol NADH min-1 mg-1 protein for the E1 and E2 isozymes, respectively.	NAD	131-135	CD59 molecule (CD59 blood group)	Homo sapiens	136-146
9709409-5	1998	RESULTS: In hypercholesterolemic patients, forearm vasodilatation was impaired in response to acetylcholine (112 +/- 20 vs. 346 +/- 30% increase in blood flow in controls, at the highest dose [15 micrograms min-1]; P < 0.0001) but not in response to sodium nitroprusside.	Acetylcholine	94-107	CD59 molecule (CD59 blood group)	Homo sapiens	207-212
9681664-4	1998	The infusion rate to induce 50% of Emax (ED50) for dopamine in the young and elderly subjects was 363 ng x min(-1) and 352 ng min(-1), and the ED50 for noradrenaline was 40.7 ng min(-1) and 43.8 ng x min(-1), respectively.	Dopamine	51-59	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
9573071-0	1998	Acquired resistance of Escherichia coli to complement lysis by binding of glycophosphoinositol-anchored protectin (CD59).	glycophosphoinositol	74-94	CD59 molecule (CD59 blood group)	Homo sapiens	115-119
9573071-1	1998	Protectin (CD59) is a glycophosphoinsitol (GPI)-anchored defender of human cells against lysis by the membrane attack complex of complement.	glycophosphoinsitol	22-41	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
9573071-1	1998	Protectin (CD59) is a glycophosphoinsitol (GPI)-anchored defender of human cells against lysis by the membrane attack complex of complement.	GPI 1046	43-46	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
9572802-7	1998	min-1) ingested either WP or a 6% (330 mosmol), 8% (400 mosmol), or a 9% (590 mosmol) CES the morning following hypohydration.	ARAMITE	86-89	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9682221-2	1998	This enzymatic activity has a K(m) of 278 +/- 35.3 microM and a V(m) of 114.7 +/- 14.7 nmol mg-1 min-1 (mean +/- SE of eight hearts) for benzylamine and is strongly inhibited by 1 mM histamine and by B24, a specific inhibitor of Bz.SSAO.	benzylamine	137-148	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
9682221-2	1998	This enzymatic activity has a K(m) of 278 +/- 35.3 microM and a V(m) of 114.7 +/- 14.7 nmol mg-1 min-1 (mean +/- SE of eight hearts) for benzylamine and is strongly inhibited by 1 mM histamine and by B24, a specific inhibitor of Bz.SSAO.	Histamine	183-192	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
9682221-2	1998	This enzymatic activity has a K(m) of 278 +/- 35.3 microM and a V(m) of 114.7 +/- 14.7 nmol mg-1 min-1 (mean +/- SE of eight hearts) for benzylamine and is strongly inhibited by 1 mM histamine and by B24, a specific inhibitor of Bz.SSAO.	1-ethyl-1,2-dihydro-1,2-azaborinine	200-203	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
9682221-2	1998	This enzymatic activity has a K(m) of 278 +/- 35.3 microM and a V(m) of 114.7 +/- 14.7 nmol mg-1 min-1 (mean +/- SE of eight hearts) for benzylamine and is strongly inhibited by 1 mM histamine and by B24, a specific inhibitor of Bz.SSAO.	Quinuclidinyl Benzilate	229-231	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
9682221-4	1998	The levels of MAo and B were assayed: MAO A showed a K(m) of 137.1 +/- 16.2 microM and a V(m) of 10.4 +/- 2.5 nmol mg-1 min-1 for serotonin; MAo B had a K(m) of 9.9 +/- 1.6 microM and V(m) of 4.3 +/- 1.1 nmol mg-1 min-1 for beta-phenylethylamine (mean +/- SE of seven hearts).	Serotonin	130-139	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
9682221-4	1998	The levels of MAo and B were assayed: MAO A showed a K(m) of 137.1 +/- 16.2 microM and a V(m) of 10.4 +/- 2.5 nmol mg-1 min-1 for serotonin; MAo B had a K(m) of 9.9 +/- 1.6 microM and V(m) of 4.3 +/- 1.1 nmol mg-1 min-1 for beta-phenylethylamine (mean +/- SE of seven hearts).	phenethylamine	224-245	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
9585008-5	1998	In the perfusion experiments, at physiologic concentrations the slow decline of TSH in the maternal circulation was associated with a small linear increase in fetal levels to 0.11 +/- 0.04% of initial dose at 2 h. The placental transfer rate was 0.08 microIU min(-1).	Thyrotropin	80-83	CD59 molecule (CD59 blood group)	Homo sapiens	259-265
9585008-7	1998	The placental permeability of TSH was 2.4 x 10(-4) mL min(-1) g(-1) and was proportional to its coefficients of diffusion in water and molecular size.	Thyrotropin	30-33	CD59 molecule (CD59 blood group)	Homo sapiens	54-60
9579493-13	1998	Isoflurane significantly increased the gain of shivering (as calculated from the initial increase), from -684 +/- 266 to -1483 +/- 752 ml x min(-1) x degrees C(-1).	Isoflurane	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	140-146
9579498-5	1998	RESULTS: In women, morphine reduced the slope of the ventilatory response to carbon dioxide from 1.8 +/- 0.9 to 1.3 +/- 0.7 l x min(-1) x mmHg(-1) (mean +/- SD; P < 0.05), whereas in men there was no significant effect (control = 2.0 +/- 0.4 vs. morphine = 1.8 +/- 0.4 l x min(-1) x mmHg(-1)).	Morphine	19-27	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
9579498-5	1998	RESULTS: In women, morphine reduced the slope of the ventilatory response to carbon dioxide from 1.8 +/- 0.9 to 1.3 +/- 0.7 l x min(-1) x mmHg(-1) (mean +/- SD; P < 0.05), whereas in men there was no significant effect (control = 2.0 +/- 0.4 vs. morphine = 1.8 +/- 0.4 l x min(-1) x mmHg(-1)).	Morphine	19-27	CD59 molecule (CD59 blood group)	Homo sapiens	276-282
9579498-5	1998	RESULTS: In women, morphine reduced the slope of the ventilatory response to carbon dioxide from 1.8 +/- 0.9 to 1.3 +/- 0.7 l x min(-1) x mmHg(-1) (mean +/- SD; P < 0.05), whereas in men there was no significant effect (control = 2.0 +/- 0.4 vs. morphine = 1.8 +/- 0.4 l x min(-1) x mmHg(-1)).	Carbon Dioxide	77-91	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
9579498-5	1998	RESULTS: In women, morphine reduced the slope of the ventilatory response to carbon dioxide from 1.8 +/- 0.9 to 1.3 +/- 0.7 l x min(-1) x mmHg(-1) (mean +/- SD; P < 0.05), whereas in men there was no significant effect (control = 2.0 +/- 0.4 vs. morphine = 1.8 +/- 0.4 l x min(-1) x mmHg(-1)).	Carbon Dioxide	77-91	CD59 molecule (CD59 blood group)	Homo sapiens	276-282
9579498-7	1998	Morphine decreased hypoxic sensitivity in women from 1.0 +/- 0.5 l x min(-1) x %(-1) to 0.5 +/- 0.4 l x min(-1) x %(-1) (P < 0.05) but did not cause a decrease in men (control = 1.0 +/- 0.5 l x min(-1) x %(-1) vs. morphine = 0.9 +/- 0.5 l x min(-1) x %(-1)).	Morphine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	69-75
9579498-7	1998	Morphine decreased hypoxic sensitivity in women from 1.0 +/- 0.5 l x min(-1) x %(-1) to 0.5 +/- 0.4 l x min(-1) x %(-1) (P < 0.05) but did not cause a decrease in men (control = 1.0 +/- 0.5 l x min(-1) x %(-1) vs. morphine = 0.9 +/- 0.5 l x min(-1) x %(-1)).	Morphine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
9579498-7	1998	Morphine decreased hypoxic sensitivity in women from 1.0 +/- 0.5 l x min(-1) x %(-1) to 0.5 +/- 0.4 l x min(-1) x %(-1) (P < 0.05) but did not cause a decrease in men (control = 1.0 +/- 0.5 l x min(-1) x %(-1) vs. morphine = 0.9 +/- 0.5 l x min(-1) x %(-1)).	Morphine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
9579498-7	1998	Morphine decreased hypoxic sensitivity in women from 1.0 +/- 0.5 l x min(-1) x %(-1) to 0.5 +/- 0.4 l x min(-1) x %(-1) (P < 0.05) but did not cause a decrease in men (control = 1.0 +/- 0.5 l x min(-1) x %(-1) vs. morphine = 0.9 +/- 0.5 l x min(-1) x %(-1)).	Morphine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
9640159-3	1998	Patients were anaesthetized with continuous infusion of propofol 200 micrograms kg-1 min-1.	Propofol	56-64	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
9640160-2	1998	Remifentanil was administered as a loading dose of 0.125, 0.25, 0.375 or 0.5 microgram kg-1 and at a maintenance infusion rate of 0.025, 0.05, 0.075 or 0.1 microgram kg-1 min-1, respectively, with an infusion of propofol 6 mg kg-1 h-1.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
9640160-3	1998	Responses occurred in 88% of patients with remifentanil 0.025 microgram kg-1 min-1 compared with 30-40% in the other groups.	Remifentanil	43-55	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
9640160-6	1998	Reductions in remifentanil doses to 0.025-0.05 microgram kg-1 min-1 resulted in adequate respiration at the end of surgery in 88% of patients.	Remifentanil	14-26	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
9787766-3	1998	At pH 7.4 and 25 degrees C, the major and minor components of the E3 isozyme catalyzed the reaction with Vmax of 1.1 and 0.8 mumol NADH min-1 mg-1 protein, respectively, compared to 0.067 and 0.060 mumol NADH min-1 mg-1 protein for the E1 and E2 isozymes, respectively.	NAD	131-135	CD59 molecule (CD59 blood group)	Homo sapiens	209-219
9787766-3	1998	At pH 7.4 and 25 degrees C, the major and minor components of the E3 isozyme catalyzed the reaction with Vmax of 1.1 and 0.8 mumol NADH min-1 mg-1 protein, respectively, compared to 0.067 and 0.060 mumol NADH min-1 mg-1 protein for the E1 and E2 isozymes, respectively.	NAD	204-208	CD59 molecule (CD59 blood group)	Homo sapiens	136-146
9492897-4	1998	In contrast, during cycling (e.g. 113 W), metoprolol reduced the increase in cardiac output (222 +/- 13 vs. 260 +/- 16%), heart rate (114 +/- 3 vs. 135 +/- 7 beats min-1) and mean arterial pressure (103 +/- 3 vs. 112 +/- 4 mmHg), and the increase in cerebral artery mean blood velocity also became lower (from 59 +/- 3 to 66 +/- 3 vs. 60 +/- 2 to 72 +/- 3 cm s-1; P < 0.05).	Metoprolol	42-52	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
9597417-6	1998	Cardiac output increased by 0.7 and 1.61.min-1 (P < 0.05 for both) after 8 and 24 micrograms.kg-1 of levosimendan, respectively.	Simendan	104-116	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
9597418-5	1998	Dobutamine was infused up to 40 mu.kg.l-1 min-1 in 3 min stages.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
9535412-5	1998	In the hypertensive group, the patients with DD genotype showed significantly less endothelium-dependent vasodilation compared with ID+II genotypes (at the highest dose of acetylcholine, forearm blood flow was 12.1+/-4.2 versus 17.0+/-4.1 mL x 100 mL tissue(-1) x min(-1)) (P<.005).	Acetylcholine	172-185	CD59 molecule (CD59 blood group)	Homo sapiens	264-270
9538246-1	1998	Human glycosyl phosphatidylinositol-anchored protein CD59 was solubilized in detergent-insoluble complexes (DICs) and in post-nuclear pellets by a two-step solubilization procedure using Triton X-100 and octylglucoside.	Glycosylphosphatidylinositols	6-35	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
9538246-1	1998	Human glycosyl phosphatidylinositol-anchored protein CD59 was solubilized in detergent-insoluble complexes (DICs) and in post-nuclear pellets by a two-step solubilization procedure using Triton X-100 and octylglucoside.	Octoxynol	187-199	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
9538246-1	1998	Human glycosyl phosphatidylinositol-anchored protein CD59 was solubilized in detergent-insoluble complexes (DICs) and in post-nuclear pellets by a two-step solubilization procedure using Triton X-100 and octylglucoside.	octyl-beta-D-glucoside	204-218	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
9525985-17	1998	min-1, with saline or ex(9-39)NH2 at 300 pmol .	Sodium Chloride	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9565925-7	1998	Heart rate and lactate concentration by an equivalent submaximal workload (5 km.h-1) were significant reduced (from 138 +/- 21 beats.min-1 to 113 +/- 20 beats.min-1, P < 0.05, and from 2.6 +/- 1.4 mmol.L-1 to 1.3 +/- 0.6 mmol.L-1, P < 0.05); all patients experienced a clear reduction of fatigue and could carry out normal daily activities again without substantial limitations.	Lactic Acid	15-22	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
9565925-7	1998	Heart rate and lactate concentration by an equivalent submaximal workload (5 km.h-1) were significant reduced (from 138 +/- 21 beats.min-1 to 113 +/- 20 beats.min-1, P < 0.05, and from 2.6 +/- 1.4 mmol.L-1 to 1.3 +/- 0.6 mmol.L-1, P < 0.05); all patients experienced a clear reduction of fatigue and could carry out normal daily activities again without substantial limitations.	Lactic Acid	15-22	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
9587962-7	1998	In 48 mM t-butylhydroperoxide, the pseudo first-order rate constants, k1 and k69, were 1.5 x 10(-3) and 2.3 x 10(-4) min-1.	tert-Butylhydroperoxide	9-29	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
18967113-3	1998	The gaseous silicon tetrafluoride is fed directly into the ICP torch by a flow of 250 ml min(-1) Ar carrier gas.	silicon tetrafluoride	12-33	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
9521333-4	1998	The vasodilator response to acetylcholine was significantly reduced in hypertensives compared with normotensives (maximum blood flow: 10.4+/-4.6 versus 14.4+/-3.7 mL x min[-1] x dL[-1]; P=.008).	Acetylcholine	28-41	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
9642772-2	1998	Polypyrrole (PPy) is directly formed by continuous passage of a buffered solution of the monomer (0.4 M) and enzyme (250 U mL-1) at pH 7 at a flow rate of 0.05-0.1 mL min-1 under a constant applied potential of +0.85 V vs Ag/AgCl decreases.	polypyrrole	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
9642772-2	1998	Polypyrrole (PPy) is directly formed by continuous passage of a buffered solution of the monomer (0.4 M) and enzyme (250 U mL-1) at pH 7 at a flow rate of 0.05-0.1 mL min-1 under a constant applied potential of +0.85 V vs Ag/AgCl decreases.	polypyrrole	13-16	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
9623443-1	1998	An end-stage renal failure patient, receiving chronic treatment with the anticonvulsants, sodium valproate and primidone, showed accelerated recovery with enhanced elimination (T1/2(z) = 52 min) and clearance (Cl = 14.4 ml min-1 kg-1) of rocuronium.	Valproic Acid	90-106	CD59 molecule (CD59 blood group)	Homo sapiens	223-233
9623443-1	1998	An end-stage renal failure patient, receiving chronic treatment with the anticonvulsants, sodium valproate and primidone, showed accelerated recovery with enhanced elimination (T1/2(z) = 52 min) and clearance (Cl = 14.4 ml min-1 kg-1) of rocuronium.	Primidone	111-120	CD59 molecule (CD59 blood group)	Homo sapiens	223-233
9568451-10	1998	The improvement in oxygen consumption after 16 weeks training was higher than after 6 weeks (+2.6 +/- 3.0 vs +0.3 +/- 3.1 ml.kg.min-1, P < 0.05).	Oxygen	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
9587731-2	1998	Isoflurane was delivered during the inspiratory phase and consumption investigated at 10, 15 and 25 cycles min-1.	Isoflurane	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
9591925-2	1998	METHODS: Ten patients scheduled for cardiac surgery presented with pulmonary hypertension (mean pulmonary artery pressure greater than 30 mmHg) after protamine injection and were treated by infusion of 0.02 microg x kg(-1) x min(-1) prostaglandin E1.	Alprostadil	233-249	CD59 molecule (CD59 blood group)	Homo sapiens	225-231
9591927-4	1998	RESULT AND CONCLUSIONS: Diltiazem caused significant venodilation at a dose of 0.01 microg x min(-1) or more, while verapamil and nicardipine only caused this effect at 1 microg x min(-1) or more.	Diltiazem	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
9591927-4	1998	RESULT AND CONCLUSIONS: Diltiazem caused significant venodilation at a dose of 0.01 microg x min(-1) or more, while verapamil and nicardipine only caused this effect at 1 microg x min(-1) or more.	Diltiazem	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	180-186
9539195-5	1998	RESULTS: The obese group presented hyperinsulinaemia in the basal state and after glucose loading (insulin area = 58+/-5 vs 33+/-3 nmol x I[-1] x 2 h, P = 0.005), insulin resistance (M value = 37.4+/-4.8 vs 50.6+/-2.6 micromol x min[-1] x kg FFM[-1], P = 0.002), and insulin hypersecretion (61.9+/-6.0 vs 33.9 +/- 4.0 nmol x 2 h, P = 0.007); endogenous glucose production was similar in the two groups.	Glucose	82-89	CD59 molecule (CD59 blood group)	Homo sapiens	229-235
28921323-2	1998	METHODS: Eighty patients of ASA physical status I or II were randomly assigned to one of four groups: sevoflurane at 3 or 61 min-1 and isoflurane at 3 or 61 min-1.	Isoflurane	135-145	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
28921323-4	1998	The consumption of sevoflurane and isoflurane was measured by weighing the bottle of liquid agent, which was greater in the groups receiving 61 min-1 gas than in those receiving 31 min-1.	Sevoflurane	19-30	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
28921323-4	1998	The consumption of sevoflurane and isoflurane was measured by weighing the bottle of liquid agent, which was greater in the groups receiving 61 min-1 gas than in those receiving 31 min-1.	Isoflurane	35-45	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
28921323-4	1998	The consumption of sevoflurane and isoflurane was measured by weighing the bottle of liquid agent, which was greater in the groups receiving 61 min-1 gas than in those receiving 31 min-1.	Isoflurane	35-45	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
9452441-6	1998	Peroxynitrite had no effect in the absence of GSH but significantly stimulated the enzyme in the presence of the thiol (3.45 +/- 0.60 micromol of cGMP x mg-1 x min-1).	Peroxynitrous Acid	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
9452441-6	1998	Peroxynitrite had no effect in the absence of GSH but significantly stimulated the enzyme in the presence of the thiol (3.45 +/- 0.60 micromol of cGMP x mg-1 x min-1).	Sulfhydryl Compounds	113-118	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
9452441-6	1998	Peroxynitrite had no effect in the absence of GSH but significantly stimulated the enzyme in the presence of the thiol (3.45 +/- 0.60 micromol of cGMP x mg-1 x min-1).	Cyclic GMP	146-150	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
9459241-4	1998	Infusion of 1.0 microg kg(-1) x min(-1) dopexamine had no effect on Q(S)/Q(T) and low V(A)/Q areas despite an increased CO (7.7 +/- 2.2 L/min versus 6.2 +/- 1.2 L/min; P < 0.01).	dopexamine	40-50	CD59 molecule (CD59 blood group)	Homo sapiens	32-38
9459241-6	1998	Infusion of 2.0 microg x kg(-1) x min(-1) dopexamine further increased CO to 8.4 +/- 2.7 L/min (P < 0.01) without alterations of Q(S)/Q(T), perfusion of low V(A)/Q areas, and Pao2.	dopexamine	42-52	CD59 molecule (CD59 blood group)	Homo sapiens	34-40
9459241-6	1998	Infusion of 2.0 microg x kg(-1) x min(-1) dopexamine further increased CO to 8.4 +/- 2.7 L/min (P < 0.01) without alterations of Q(S)/Q(T), perfusion of low V(A)/Q areas, and Pao2.	pao2	178-182	CD59 molecule (CD59 blood group)	Homo sapiens	34-40
9459241-7	1998	We concluded that dopexamine (1.0 microg x kg(-1) x min(-1) and 2.0 microg x kg(-1) x min(-1)) has no adverse effects on V(A)/Q relationships and Q(S)/Q(T) in anesthetized, paralyzed patients.	dopexamine	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	52-58
9459241-11	1998	Dopexamine (1.0 microg x kg(-1) x min(-1) and 2.0 microg x kg(-1) min(-1)) improved cardiac output and oxygenation without alterations of intrapulmonary shunt.	dopexamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	34-40
9459241-11	1998	Dopexamine (1.0 microg x kg(-1) x min(-1) and 2.0 microg x kg(-1) min(-1)) improved cardiac output and oxygenation without alterations of intrapulmonary shunt.	dopexamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	66-72
9602580-4	1998	With isoflurane, mean rate decreased from 72 (SD 9.7) to 67 (10.4) beat min-1 and with halothane from 76 (10.1) to 65 (9.1) beat min-1 (P < 0.05).	Isoflurane	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
9602580-4	1998	With isoflurane, mean rate decreased from 72 (SD 9.7) to 67 (10.4) beat min-1 and with halothane from 76 (10.1) to 65 (9.1) beat min-1 (P < 0.05).	Halothane	87-96	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
9602580-6	1998	Cardiac index decreased from 3.1 (1.03) to 2.7 (0.71) litre min-1 m-2 with isoflurane and from 3.1 (0.98) to 2.5 (0.57) litre min-1 m-2 with halothane (P < 0.05).	Isoflurane	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
9614505-4	1998	Maximum rate (Vmax) of uptake in absence or in presence of ryanodine was lower in inner peri-infarct (7.4 +/- 0.7 and 9.5 +/- 0.8 nmol min-1 mg-1 of protein, respectively; mean +/- SEM) and outer peri-infarct tissues (8.8 +/- 0.8 and 12.0 +/- 0.8 nmol min-1 mg-1) than in infarct-remote myocardium (12.7 +/- 2.1 and 15.8 +/- 2.2 nmol min-1 mg-1).	Ryanodine	59-68	CD59 molecule (CD59 blood group)	Homo sapiens	135-145
9536919-2	1998	In order to evaluate factors influencing thermogenesis in obesity, energy expenditure was measured before and during an adrenaline infusion (25 ng min-1 kg-1 ideal body weight for 30 min) in 22 obese females.	Epinephrine	120-130	CD59 molecule (CD59 blood group)	Homo sapiens	147-157
9536924-8	1998	At one visit, 40 mumol min-1 kg-1 sodium lactate was infused, and at the other, normal saline.	Sodium Lactate	34-48	CD59 molecule (CD59 blood group)	Homo sapiens	23-33
9536926-8	1998	The glucose infusion rate was significantly increased after infusion of NG-monomethyl L-arginine (8.9 +/- 0.9 compared with 7.9 +/- 0.8 mg min-1 kg-1 for placebo; P = 0.002).	Glucose	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	139-149
9536926-8	1998	The glucose infusion rate was significantly increased after infusion of NG-monomethyl L-arginine (8.9 +/- 0.9 compared with 7.9 +/- 0.8 mg min-1 kg-1 for placebo; P = 0.002).	omega-N-Methylarginine	72-96	CD59 molecule (CD59 blood group)	Homo sapiens	139-149
9536926-9	1998	Whole-body glucose uptake increased during the clamp, with values of 9.4 +/- 0.7 and 10.9 +/- 0.8 mg min-1 kg-1 for placebo and NG-monomethyl L-arginine respectively (P = 0.036; 95% confidence interval 0.2,2.8).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	101-111
9536926-9	1998	Whole-body glucose uptake increased during the clamp, with values of 9.4 +/- 0.7 and 10.9 +/- 0.8 mg min-1 kg-1 for placebo and NG-monomethyl L-arginine respectively (P = 0.036; 95% confidence interval 0.2,2.8).	omega-N-Methylarginine	128-152	CD59 molecule (CD59 blood group)	Homo sapiens	101-111
9498656-5	1998	NIDDM patients had increased lactate turnover rates (16.18+/-0.92 vs 12.14+/-0.60 micromol x kg(-1) x min(-1), p < 0.01) and a moderate rise in glucose production (EGP) (15.39+/-0.87 vs 12.52+/-0.28 micromol x kg(-1) x min(-1) , p = 0.047).	Lactic Acid	29-36	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
9597383-6	1998	The lower SI in obese subjects was a consequence P3 parameter (0.178 +/- 0.08 vs. 0.440 +/- 0.26.10(-5) min-2 (pmol.l-1)-1, P < 0.01), being p2 similar between obese and lean subjects (0.389 +/- 0.19 vs. 0.376 +/- 0.19.10(-1) min-1, NS).	Silicon	10-12	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
9597383-6	1998	The lower SI in obese subjects was a consequence P3 parameter (0.178 +/- 0.08 vs. 0.440 +/- 0.26.10(-5) min-2 (pmol.l-1)-1, P < 0.01), being p2 similar between obese and lean subjects (0.389 +/- 0.19 vs. 0.376 +/- 0.19.10(-1) min-1, NS).	Silicon	10-12	CD59 molecule (CD59 blood group)	Homo sapiens	229-234
9535583-8	1998	When averaged across conditions, oxygen consumption (VO2) increased significantly (P < 0.01) from pre- to post-test [from 38.5 to 40.5 ml x kg(-1) x min(-1) at 200 m x min(-1), and from 53.1 to 54.5 ml x kg(-1) x min(-1) at 268 m x min(-1), respectively].	Oxygen	33-39	CD59 molecule (CD59 blood group)	Homo sapiens	152-158
9535583-8	1998	When averaged across conditions, oxygen consumption (VO2) increased significantly (P < 0.01) from pre- to post-test [from 38.5 to 40.5 ml x kg(-1) x min(-1) at 200 m x min(-1), and from 53.1 to 54.5 ml x kg(-1) x min(-1) at 268 m x min(-1), respectively].	Oxygen	33-39	CD59 molecule (CD59 blood group)	Homo sapiens	171-177
9535583-8	1998	When averaged across conditions, oxygen consumption (VO2) increased significantly (P < 0.01) from pre- to post-test [from 38.5 to 40.5 ml x kg(-1) x min(-1) at 200 m x min(-1), and from 53.1 to 54.5 ml x kg(-1) x min(-1) at 268 m x min(-1), respectively].	Oxygen	33-39	CD59 molecule (CD59 blood group)	Homo sapiens	171-177
9535583-8	1998	When averaged across conditions, oxygen consumption (VO2) increased significantly (P < 0.01) from pre- to post-test [from 38.5 to 40.5 ml x kg(-1) x min(-1) at 200 m x min(-1), and from 53.1 to 54.5 ml x kg(-1) x min(-1) at 268 m x min(-1), respectively].	Oxygen	33-39	CD59 molecule (CD59 blood group)	Homo sapiens	171-177
9472974-5	1998	After indomethacin, the plasma glucose concentration and glucose production increased in all subjects from 5.3 +/- 0.1 mmol/L to a maximum of 7.1 +/- 0.3 mmol/L (P < .05) and from 17.6 +/- 0.8 micromol x kg(-1) x min(-1) to a maximum of 26.2 +/- 2.5 micromol x kg(-1) x min(-1) (P < .05), respectively.	Indomethacin	6-18	CD59 molecule (CD59 blood group)	Homo sapiens	273-279
9472974-5	1998	After indomethacin, the plasma glucose concentration and glucose production increased in all subjects from 5.3 +/- 0.1 mmol/L to a maximum of 7.1 +/- 0.3 mmol/L (P < .05) and from 17.6 +/- 0.8 micromol x kg(-1) x min(-1) to a maximum of 26.2 +/- 2.5 micromol x kg(-1) x min(-1) (P < .05), respectively.	Indomethacin	6-18	CD59 molecule (CD59 blood group)	Homo sapiens	216-222
9511179-6	1998	Critically, the two co-expressed proteins were able to couple to form a NADPH-dependent monooxygenase which metabolized the CYP2D6 substrate bufuralol (Vmax 3.30 nmol min-1 mg-1 protein; K(m) 11.1 microM) in isolated membrane fractions.	bufuralol	141-150	CD59 molecule (CD59 blood group)	Homo sapiens	167-177
9523311-6	1998	RESULTS: Preliminary in vitro results have demonstrated that the bFGF flux increased from 1.4 +/- 0.13 ng min-1 cm-2 to 3.2 +/- 0.38 ng min-1 cm-2 with the addition of 15 mM Na+ glycocholate (NaG) to the donor solution.	na+ glycocholate	174-190	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
9523311-6	1998	RESULTS: Preliminary in vitro results have demonstrated that the bFGF flux increased from 1.4 +/- 0.13 ng min-1 cm-2 to 3.2 +/- 0.38 ng min-1 cm-2 with the addition of 15 mM Na+ glycocholate (NaG) to the donor solution.	nag	192-195	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
9523311-10	1998	Addition of NaG further increased the flux to 8.5 +/- 1.1 ng min-1 cm-2 which was approximately 3- to 3.5-fold greater than that determined with the protein alone in the absence of any donor phase additives.	nag	12-15	CD59 molecule (CD59 blood group)	Homo sapiens	61-71
9616529-7	1998	At the end of 12 months of treatment with salmeterol, the adjusted change from baseline for morning and evening peak expiratory flow rate (PEF) was 56 and 47 l min-1, respectively, and this was significantly greater than placebo (P < 0.01; P < 0.05).	Salmeterol Xinafoate	42-52	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
9458749-7	1998	Quantitative analysis of the spin-coupling patterns provided an estimate of the turnover rate of hepatic ascorbic acid in vivo (1.9 +/- 0.4 nmol.min-1.g-1) and a novel approach toward a better understanding of optimal ascorbic acid requirements in humans.	Ascorbic Acid	105-118	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
9512947-2	1998	METHODS: Dopamine was administered as an intravenous infusion (2 micrograms kg-1 min-1).	Dopamine	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
9625275-4	1998	The mean estimates of ritodrine sulphation rate were 490 pmol x min(-1) x mg(-1) (duodenum) and 140 pmol x min(-1) x mg(-1) (liver).	Ritodrine	22-31	CD59 molecule (CD59 blood group)	Homo sapiens	64-70
9625275-7	1998	In the liver, 30% and 70% of the population fell into two subgroups with the mean estimates of ritodrine sulphation rate of 114 and 149 pmol x min(-1) x mg(-1), respectively (P < 0.05).	Ritodrine	95-104	CD59 molecule (CD59 blood group)	Homo sapiens	143-149
9625275-8	1998	In the duodenum, 25% and 75% of the population fell into two subgroups and the mean estimates of ritodrine sulphation rate were 332 and 538 pmol x min(-1) x mg(-1), respectively (P < 0.05).	Ritodrine	97-106	CD59 molecule (CD59 blood group)	Homo sapiens	147-153
9701703-2	1998	Administration of a single dose of glucagon (0.1 mg/kg) caused an increase in glucose production rate by near 140% from 4.2 to 10.1 mg.kg-1.min-1.	Glucagon	35-43	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
9701703-2	1998	Administration of a single dose of glucagon (0.1 mg/kg) caused an increase in glucose production rate by near 140% from 4.2 to 10.1 mg.kg-1.min-1.	Glucose	78-85	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
9701703-5	1998	The amount of glycerol converted to glucose by gluconeogenesis was 9.1 micromol.kg-1.min-1 before and 10.5 micromol.	Glycerol	14-22	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
9701703-5	1998	The amount of glycerol converted to glucose by gluconeogenesis was 9.1 micromol.kg-1.min-1 before and 10.5 micromol.	Glucose	36-43	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
9701703-6	1998	kg-1.min-1 after glucagon administration.	Glucagon	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	5-10
9481683-4	1998	The increase in the Vmax for L-arginine transport (9.0 +/- 1.1) pmol (micrograms protein)-1 min-1) in diabetic endothelial cells cultured in 5 mM D-glucose was unaffected following 24 h exposure to 25 mM D-glucose.	Arginine	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
9481683-4	1998	The increase in the Vmax for L-arginine transport (9.0 +/- 1.1) pmol (micrograms protein)-1 min-1) in diabetic endothelial cells cultured in 5 mM D-glucose was unaffected following 24 h exposure to 25 mM D-glucose.	Glucose	146-155	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
9475660-5	1998	The mean peak oxygen uptake was 22.6 and 15.1 mL x kg(-1) x min(-1) among PA and CO, respectively.	Oxygen	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
9475660-5	1998	The mean peak oxygen uptake was 22.6 and 15.1 mL x kg(-1) x min(-1) among PA and CO, respectively.	Protactinium	74-76	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
9475660-5	1998	The mean peak oxygen uptake was 22.6 and 15.1 mL x kg(-1) x min(-1) among PA and CO, respectively.	Cobalt	81-83	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
9481731-7	1998	The mass transfer area coefficient of creatinine, representing effective peritoneal surface area, decreased from 10.7 +/- 1.3 ml/min/1.73 m2 (recumbent) to 9.9 +/- 1.4 (upright; P = 0.08).	Creatinine	38-48	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
9549747-6	1998	With sevoflurane, there was an increase in heart rate from baseline of 74 +/- 7 beats.min-1 to a maximum of 83 +/- 13 beats.min-1 (P = 0.038).	Sevoflurane	5-16	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
9549747-6	1998	With sevoflurane, there was an increase in heart rate from baseline of 74 +/- 7 beats.min-1 to a maximum of 83 +/- 13 beats.min-1 (P = 0.038).	Sevoflurane	5-16	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
9549747-7	1998	One patient required three intravenous doses of esmolol (10mg each) for a heart rate in excess of 100 beats.min-1.	esmolol	48-55	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
9672927-4	1998	The composition of the FGF (600 ml.min-1) was calculated as follows: oxygen necessary for consumption (60 ml.min-1) plus the remaining FGF in a 1:2 relationship for oxygen.	Oxygen	69-75	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
9672927-4	1998	The composition of the FGF (600 ml.min-1) was calculated as follows: oxygen necessary for consumption (60 ml.min-1) plus the remaining FGF in a 1:2 relationship for oxygen.	Oxygen	165-171	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
9857660-9	1998	The oxygen uptake at the LT amounted to 1734 +/- 282 ml.min-1 and corresponded to 48% of VO2 max (3726 +/- 363 ml.min-1).	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
9857660-9	1998	The oxygen uptake at the LT amounted to 1734 +/- 282 ml.min-1 and corresponded to 48% of VO2 max (3726 +/- 363 ml.min-1).	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
10453750-7	1998	The total net oxygen consumed throughout the 6 min cycling period at pedalling rates of 40, 60, 80, 100 and 120 rev.min(-1) amounted to 7.727+/-1.197, 7.705+/-1.548, 8.679+/-1.262, 9.945+/-1.435 and 13.720+/-1.862 l, respectively for each pedalling rate.	Oxygen	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
9398310-2	1997	Incubation of the enzyme with 10-50 microM GSNO led to a time- and concentration-dependent inactivation of the enzyme, with a second-order rate constant of 0.087 +/- 0.009 M-1 min-1.	S-Nitrosoglutathione	43-47	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
9495571-5	1997	For cholic acid 7alpha-dehydroxylation: zero order kinetics were found over 7.5 min at 37 degrees C, under anaerobic conditions (pH optimum 8.0), with Km and Vmax values of 5.23 x 10(-8) mol/l and 1.88 x 10(-7) mol DCA min(-1) mg prot(-1), respectively.	Cholic Acid	4-15	CD59 molecule (CD59 blood group)	Homo sapiens	219-225
9388243-8	1997	ATP was hydrolyzed in proportion to the amount of purified protein assayed, and typical Michaelis-Menten behavior was exhibited, yielding estimations of Km of approximately 3.0 mM and Vmax of 0.46 micromol mg-1 min-1.	Adenosine Triphosphate	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
9429045-6	1997	She required an epinephrine infusion of 0.4 microgram.kg-1.min-1 and prolonged ICU admission.	Epinephrine	16-27	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
9431833-4	1997	RESULTS: Following intra-arterial infusion of BQ-123 (50 nmol min-1) for 5 min, forearm blood flow increased by approximately 60% over the next 60 minutes; lower doses were without significant effect.	cyclo(Trp-Asp-Pro-Val-Leu)	46-52	CD59 molecule (CD59 blood group)	Homo sapiens	62-74
9392488-6	1997	On one occasion, glucagon was infused at a rate of 0.65 ng x kg(-1) x min(-1) throughout the experiment, resulting in glucagon concentrations of approximately 130 pg/ml and a slow but comparable fall in endogenous glucose production with time in both groups.	Glucagon	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	70-76
9392488-7	1997	On the other two occasions, the glucagon infusion was increased at 10:00 A.M. to either 1.5 or 3.0 ng x kg(-1) x min(-1), resulting in an increase in glucagon concentrations to approximately 180 and 310 pg/ml, respectively.	Glucagon	32-40	CD59 molecule (CD59 blood group)	Homo sapiens	113-119
9392488-10	1997	The specific activity of glycogen, calculated as the integrated release of [6-3H]glucose divided by the integrated release of unlabeled glucose, was lower (P < 0.05) in diabetic subjects than in nondiabetic subjects during both the 1.5 ng x kg(-1) x min(-1) (19.0 +/- 3.9 vs. 41.4 +/- 5.7 dpm/micromol) and 3.0 ng x kg(-1) x min(-1) (19.1 +/- 3.1 vs. 36.5 +/- 7.2 dpm/micromol) glucagon infusions, implying that a greater portion of the glucose released from glycogen was derived from the indirect pathway.	Glycogen	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	253-259
9392488-10	1997	The specific activity of glycogen, calculated as the integrated release of [6-3H]glucose divided by the integrated release of unlabeled glucose, was lower (P < 0.05) in diabetic subjects than in nondiabetic subjects during both the 1.5 ng x kg(-1) x min(-1) (19.0 +/- 3.9 vs. 41.4 +/- 5.7 dpm/micromol) and 3.0 ng x kg(-1) x min(-1) (19.1 +/- 3.1 vs. 36.5 +/- 7.2 dpm/micromol) glucagon infusions, implying that a greater portion of the glucose released from glycogen was derived from the indirect pathway.	Glycogen	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	328-334
9371784-7	1997	Highly mobile membrane components, phosphatidylethanolamine- and glycosylphosphatidylinositol-linked CD59 with no specific skeletal association were enriched in the vesicle.	Glycosylphosphatidylinositols	65-93	CD59 molecule (CD59 blood group)	Homo sapiens	101-105
9399971-2	1997	PAH was eliminated from the ipsilateral cerebrum extensively with an apparent efflux rate constant of 0.0587 (min-1) after microinjection into a cerebral cortex region termed Par2.	p-Aminohippuric Acid	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
9398165-5	1997	The reaction of H2O2 and NHA with nNOS was at least 10-fold slower than the reaction of NADPH, O2, and NHA (Vmax,app = 49 +/- 2 nmol min-1 mg-1 for the reactions with 10 microM added H4B).	Hydrogen Peroxide	16-20	CD59 molecule (CD59 blood group)	Homo sapiens	133-143
9398165-5	1997	The reaction of H2O2 and NHA with nNOS was at least 10-fold slower than the reaction of NADPH, O2, and NHA (Vmax,app = 49 +/- 2 nmol min-1 mg-1 for the reactions with 10 microM added H4B).	NADP	88-93	CD59 molecule (CD59 blood group)	Homo sapiens	133-143
9398165-5	1997	The reaction of H2O2 and NHA with nNOS was at least 10-fold slower than the reaction of NADPH, O2, and NHA (Vmax,app = 49 +/- 2 nmol min-1 mg-1 for the reactions with 10 microM added H4B).	Oxygen	18-20	CD59 molecule (CD59 blood group)	Homo sapiens	133-143
9404175-4	1997	Intra-operative bradycardia (heart rate < 60 beat.min-1) occurred more often in the buprenorphine group.	Buprenorphine	87-100	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
9386153-6	1997	After dobutamine infusion, blood flow increased less in contractile reserve-negative (0.63+/-0.38 mL x g(-1) x min(-1)) than in contractile reserve-positive (1.28+/-0.65 mL x g(-1) x min(-1)) and normal segments (1.93+/-0.83 mL x g(-1) x min(-1), P<.0001).	Dobutamine	6-16	CD59 molecule (CD59 blood group)	Homo sapiens	111-117
9386153-6	1997	After dobutamine infusion, blood flow increased less in contractile reserve-negative (0.63+/-0.38 mL x g(-1) x min(-1)) than in contractile reserve-positive (1.28+/-0.65 mL x g(-1) x min(-1)) and normal segments (1.93+/-0.83 mL x g(-1) x min(-1), P<.0001).	Dobutamine	6-16	CD59 molecule (CD59 blood group)	Homo sapiens	183-189
9386153-6	1997	After dobutamine infusion, blood flow increased less in contractile reserve-negative (0.63+/-0.38 mL x g(-1) x min(-1)) than in contractile reserve-positive (1.28+/-0.65 mL x g(-1) x min(-1)) and normal segments (1.93+/-0.83 mL x g(-1) x min(-1), P<.0001).	Dobutamine	6-16	CD59 molecule (CD59 blood group)	Homo sapiens	183-189
9386153-7	1997	Likewise, myocardial oxygen consumption was lower at rest in contractile reserve-negative (clearance rate of [11C]acetate, 0.043+/-0.012 min(-1)) than in contractile reserve-positive (0.048+/-0.01 min(-1)) and normal segments (0.058+/-0.008 min(-1), P<.02).	Oxygen	21-27	CD59 molecule (CD59 blood group)	Homo sapiens	137-143
9386153-7	1997	Likewise, myocardial oxygen consumption was lower at rest in contractile reserve-negative (clearance rate of [11C]acetate, 0.043+/-0.012 min(-1)) than in contractile reserve-positive (0.048+/-0.01 min(-1)) and normal segments (0.058+/-0.008 min(-1), P<.02).	Oxygen	21-27	CD59 molecule (CD59 blood group)	Homo sapiens	197-203
9386153-7	1997	Likewise, myocardial oxygen consumption was lower at rest in contractile reserve-negative (clearance rate of [11C]acetate, 0.043+/-0.012 min(-1)) than in contractile reserve-positive (0.048+/-0.01 min(-1)) and normal segments (0.058+/-0.008 min(-1), P<.02).	Oxygen	21-27	CD59 molecule (CD59 blood group)	Homo sapiens	197-203
9386153-7	1997	Likewise, myocardial oxygen consumption was lower at rest in contractile reserve-negative (clearance rate of [11C]acetate, 0.043+/-0.012 min(-1)) than in contractile reserve-positive (0.048+/-0.01 min(-1)) and normal segments (0.058+/-0.008 min(-1), P<.02).	Carbon-11	110-113	CD59 molecule (CD59 blood group)	Homo sapiens	137-143
9386153-8	1997	Myocardial oxygen consumption with dobutamine increased less in contractile reserve-negative (0.060+/-0.013 min(-1)) than in contractile reserve-positive (0.077+/-0.016 min(-1)) and normal segments (0.092+/-0.024 min(-1), P<.0001).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
9386153-8	1997	Myocardial oxygen consumption with dobutamine increased less in contractile reserve-negative (0.060+/-0.013 min(-1)) than in contractile reserve-positive (0.077+/-0.016 min(-1)) and normal segments (0.092+/-0.024 min(-1), P<.0001).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	169-175
9386153-8	1997	Myocardial oxygen consumption with dobutamine increased less in contractile reserve-negative (0.060+/-0.013 min(-1)) than in contractile reserve-positive (0.077+/-0.016 min(-1)) and normal segments (0.092+/-0.024 min(-1), P<.0001).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	169-175
9386153-8	1997	Myocardial oxygen consumption with dobutamine increased less in contractile reserve-negative (0.060+/-0.013 min(-1)) than in contractile reserve-positive (0.077+/-0.016 min(-1)) and normal segments (0.092+/-0.024 min(-1), P<.0001).	Dobutamine	35-45	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
9386153-8	1997	Myocardial oxygen consumption with dobutamine increased less in contractile reserve-negative (0.060+/-0.013 min(-1)) than in contractile reserve-positive (0.077+/-0.016 min(-1)) and normal segments (0.092+/-0.024 min(-1), P<.0001).	Dobutamine	35-45	CD59 molecule (CD59 blood group)	Homo sapiens	169-175
9386153-8	1997	Myocardial oxygen consumption with dobutamine increased less in contractile reserve-negative (0.060+/-0.013 min(-1)) than in contractile reserve-positive (0.077+/-0.016 min(-1)) and normal segments (0.092+/-0.024 min(-1), P<.0001).	Dobutamine	35-45	CD59 molecule (CD59 blood group)	Homo sapiens	169-175
9325424-5	1997	Using M. capsulatus Bath ferrocytochrome c555 as the electron donor, the KM and Vmax for peroxide reduction were 510 +/- 100 nM and 425 +/- 22 mol ferrocytochrome c555 oxidized min-1 (mole cytochrome c peroxidase)-1, respectively.	Peroxides	89-97	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
9413609-3	1997	According to the aforementioned studies, the appropriate conditions for separation of PCBs in presence of CTAB in a hydro-alcoholic medium are: percentage of 1-Propanol 55% (v/v), concentration of CTAB 5.0 x 10(-3) M, temperature 50 +/- 1 degrees C and mobile phase flow 1 ml min-1.	Polychlorinated Biphenyls	86-90	CD59 molecule (CD59 blood group)	Homo sapiens	276-281
9384466-3	1997	Ro 48-8684 was infused in doses of 0.1-0.3-1 mg in the first group, and 1-3-10 mg in the second, with different infusion rates (expressed as mg min(-1)) among doses.	Ro 48-8684	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	144-150
9466090-2	1997	In group A, preload was increased by the administration of hydroxyethylstarch 30 mL min-1.	hydroxyethylstarch	59-77	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
9329954-6	1997	Whole body insulin-stimulated glucose uptake was decreased in the patients (15.6+/-2.1 vs. 23.1+/-2.0 micromol x kg-1 x min-1).	Glucose	30-37	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
9445538-7	1997	In anoxic chemostats with a mixture of formate and glucose as the carbon and electron source, C2Cl4 was transformed at high rates (above 140 micromol 1-1 h-1, corresponding to 145 nmol Cl- min-1 mg protein-1), into cis-C2H2Cl2 and C2H3Cl.	formic acid	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	189-194
9445538-7	1997	In anoxic chemostats with a mixture of formate and glucose as the carbon and electron source, C2Cl4 was transformed at high rates (above 140 micromol 1-1 h-1, corresponding to 145 nmol Cl- min-1 mg protein-1), into cis-C2H2Cl2 and C2H3Cl.	Glucose	51-58	CD59 molecule (CD59 blood group)	Homo sapiens	189-194
9445538-7	1997	In anoxic chemostats with a mixture of formate and glucose as the carbon and electron source, C2Cl4 was transformed at high rates (above 140 micromol 1-1 h-1, corresponding to 145 nmol Cl- min-1 mg protein-1), into cis-C2H2Cl2 and C2H3Cl.	Tetrachloroethylene	94-99	CD59 molecule (CD59 blood group)	Homo sapiens	189-194
9445538-11	1997	The maximum capacity for chloroethene (the sum of tri-, di- and monochloro derivatives removed) degradation in the oxic chemostat was 95 micromol 1-1 h-1 (20 nmol min-1 mg protein-1), and that of the combined anoxic --> oxic reactor system was 43.4 micromol 1-1 h-1.	Vinyl Chloride	25-37	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
9354317-5	1997	RESULTS: This study showed that tedisamil exerted a significant (P<0.05) bradycardic action at rest (-10 beats min(-1); 95% CI: -6 to -15 beats min(-1)) similar to atenolol (-14 beats min(-1); -11 to -17) and drug combination (-9 beats min(-1); -6 to -12).	tedisamil	32-41	CD59 molecule (CD59 blood group)	Homo sapiens	114-120
9389267-6	1997	infusion of NTG 4-8 micrograms kg-1 min-1 significantly inhibited platelet aggregation and the increase in intracellular Ca2+ concentration (first phase, mean 439.9 (SEM 68.7) vs 210.6 (38.7) nmol litre-1; second phase, 154.4 (19.8) vs 106.7 (18.0) nmol litre-1).	Nitroglycerin	12-15	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
9354317-5	1997	RESULTS: This study showed that tedisamil exerted a significant (P<0.05) bradycardic action at rest (-10 beats min(-1); 95% CI: -6 to -15 beats min(-1)) similar to atenolol (-14 beats min(-1); -11 to -17) and drug combination (-9 beats min(-1); -6 to -12).	tedisamil	32-41	CD59 molecule (CD59 blood group)	Homo sapiens	147-153
9348445-14	1997	Finally, the use of human cell lines genetically engineered for expression of human P450s demonstrated that P450 2E1 and 3A4 hydroxylated 4-nitrophenol with turnovers of 19.5 and 1.65 min-1, respectively.	4-nitrophenol	138-151	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
9354317-5	1997	RESULTS: This study showed that tedisamil exerted a significant (P<0.05) bradycardic action at rest (-10 beats min(-1); 95% CI: -6 to -15 beats min(-1)) similar to atenolol (-14 beats min(-1); -11 to -17) and drug combination (-9 beats min(-1); -6 to -12).	tedisamil	32-41	CD59 molecule (CD59 blood group)	Homo sapiens	147-153
9354317-5	1997	RESULTS: This study showed that tedisamil exerted a significant (P<0.05) bradycardic action at rest (-10 beats min(-1); 95% CI: -6 to -15 beats min(-1)) similar to atenolol (-14 beats min(-1); -11 to -17) and drug combination (-9 beats min(-1); -6 to -12).	tedisamil	32-41	CD59 molecule (CD59 blood group)	Homo sapiens	147-153
9347274-5	1997	At 20 W, chronic heart failure patients had a leg flow similar to controls, but showed increased lactate release (from resting 11.7 +/- 33 to 142 +/- 125 micrograms.min-1 P < 0.0001 vs controls, from resting 5.7 +/- 15.4 to 50 +/- 149 micrograms.min-1 ns), higher arterial concentration of free fatty acids (781 +/- 69 vs 481 +/- 85 mumol.l-1; P < 0.01), lower femoral vein HCO3 (24.1 +/- 2.6 vs 26.3 +/- 1.7 mmol.l-1; P < 0.05) and base excess (-2.3 +/- 2.3 vs -0.24 +/- 1.7 mmol.l-1; P = 0.01).	Lactic Acid	97-104	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
9373762-4	1997	Infusions of cisplatin decreased glomerular filtration rate by 17 +/- 25 mL min-1 (P = 0.049 vs. baseline) and effective renal plasma flow by 94 +/- 150 mL min-1 (P = 0.049 vs. baseline) in the placebo group.	Cisplatin	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
9373762-4	1997	Infusions of cisplatin decreased glomerular filtration rate by 17 +/- 25 mL min-1 (P = 0.049 vs. baseline) and effective renal plasma flow by 94 +/- 150 mL min-1 (P = 0.049 vs. baseline) in the placebo group.	Cisplatin	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
9373762-5	1997	In the linotroban group a decrease in glomerular filtration rate by 11 +/- 18 mL min-1 (P = 0.050 vs. baseline) and in effective renal plasma flow by 26 +/- 63 mL min-1 (P = 0.2 vs. baseline) was noted.	linotroban	7-17	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
9373762-5	1997	In the linotroban group a decrease in glomerular filtration rate by 11 +/- 18 mL min-1 (P = 0.050 vs. baseline) and in effective renal plasma flow by 26 +/- 63 mL min-1 (P = 0.2 vs. baseline) was noted.	linotroban	7-17	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
9387942-6	1997	The mean increase in morning peak expiratory flow (PEF) was 28 L x min(-1) after budesonide treatment compared with no increase in the placebo group (p=0.011).	Budesonide	81-91	CD59 molecule (CD59 blood group)	Homo sapiens	67-73
9387942-9	1997	During the 6 month follow-up, the PEF values of the patients who had previously been treated with budesonide decreased by 18 L x min(-1) while the PD20 decreased by approximately one doubling dose step.	Budesonide	98-108	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
9387958-7	1997	Salmeterol produced a significant increase in PEFR compared to the run-in period (morning 375+/-23 vs 332+/-23 L x min(-1), deltaPEFR +15.1+/-3.1%, p<0.003; evening 384+/-24 vs 349+/-24 L x min(-1), deltaPEFR +11.7+/-2.4%, p<0.04).	Salmeterol Xinafoate	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
9387958-7	1997	Salmeterol produced a significant increase in PEFR compared to the run-in period (morning 375+/-23 vs 332+/-23 L x min(-1), deltaPEFR +15.1+/-3.1%, p<0.003; evening 384+/-24 vs 349+/-24 L x min(-1), deltaPEFR +11.7+/-2.4%, p<0.04).	Salmeterol Xinafoate	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	193-199
9276743-1	1997	Protectin (CD59), a glycosylphosphatidylinositol-anchored cell membrane glycoprotein, is differentially expressed on melanocytic cells and represents the main restriction factor of C-mediated lysis of melanoma cells.	Glycosylphosphatidylinositols	20-48	CD59 molecule (CD59 blood group)	Homo sapiens	0-9
9369046-9	1997	It was concluded in this study that LFA using the FGF of 600 ml.min-1 with setting of 3% sevoflurane, 50% oxygen and nitrous oxide, could be performed safely without risks such as hypoxia and severe delay of induction for patients weighing 53 +/- 5 kg for a duration of 5 hours.	lfa	36-39	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
9369046-9	1997	It was concluded in this study that LFA using the FGF of 600 ml.min-1 with setting of 3% sevoflurane, 50% oxygen and nitrous oxide, could be performed safely without risks such as hypoxia and severe delay of induction for patients weighing 53 +/- 5 kg for a duration of 5 hours.	Sevoflurane	89-100	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
9369046-9	1997	It was concluded in this study that LFA using the FGF of 600 ml.min-1 with setting of 3% sevoflurane, 50% oxygen and nitrous oxide, could be performed safely without risks such as hypoxia and severe delay of induction for patients weighing 53 +/- 5 kg for a duration of 5 hours.	Oxygen	106-112	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
9369046-9	1997	It was concluded in this study that LFA using the FGF of 600 ml.min-1 with setting of 3% sevoflurane, 50% oxygen and nitrous oxide, could be performed safely without risks such as hypoxia and severe delay of induction for patients weighing 53 +/- 5 kg for a duration of 5 hours.	Nitrous Oxide	117-130	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
15625824-2	1997	METHODS: RBC, and PMN from peripheral blood and mononuclear cells (MNCs) from bone marrow of 29 PNH patients were treated with FITC labelled anti-CD59 monoclonal antibody.	Fluorescein-5-isothiocyanate	127-131	CD59 molecule (CD59 blood group)	Homo sapiens	146-150
9323075-5	1997	Coronary flow reserve was obtained from the ratio of adenosine-induced (0.14 mg x kg(-1) x min(-1) I.V.)	Adenosine	53-62	CD59 molecule (CD59 blood group)	Homo sapiens	91-97
9315619-5	1997	In contrast, the floatability of endothelial GPI-anchored CD59 was markedly diminished, not only by octylglucoside, but also by increasing concentrations of Triton X-100.	octyl-beta-D-glucoside	100-114	CD59 molecule (CD59 blood group)	Homo sapiens	58-62
9315619-5	1997	In contrast, the floatability of endothelial GPI-anchored CD59 was markedly diminished, not only by octylglucoside, but also by increasing concentrations of Triton X-100.	Octoxynol	157-169	CD59 molecule (CD59 blood group)	Homo sapiens	58-62
9296410-7	1997	Propofol was infused at 0, 25, 50, or 75 microg x kg(-1) x min(-1) during the operation.	Propofol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	59-65
9296410-13	1997	Higher infusion rates of propofol (50-75 microg x kg(-1) x min(-1)) produced significant amnesia, opioid-sparing effects (alfentanil 0.3 +/- 0.2 vs 0.6 +/- 0.2 microg x kg(-1) x min(-1)), and less postoperative nausea and vomiting (P < 0.05).	Propofol	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	59-65
9296410-13	1997	Higher infusion rates of propofol (50-75 microg x kg(-1) x min(-1)) produced significant amnesia, opioid-sparing effects (alfentanil 0.3 +/- 0.2 vs 0.6 +/- 0.2 microg x kg(-1) x min(-1)), and less postoperative nausea and vomiting (P < 0.05).	Propofol	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	178-184
9296410-15	1997	Thus, in healthy outpatients premedicated with midazolam, 2 mg I.V., a propofol infusion of 25-50 microg x kg(-1) x min(-1) in combination with an alfentanil infusion of 0.2-0.4 microg x kg(-1) x min(-1) is recommended for sedation and analgesia during MAC in the ambulatory setting.	Propofol	71-79	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
9349062-5	1997	When the first twitch of the train-of-four had recovered to 5% of control, an infusion of cisatracurium 3 micrograms.kg-1.min-1 was started in Group C and an infusion of atracurium 10 micrograms.kg-1.min-1 was started in Group A.	cisatracurium	90-103	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
9349062-13	1997	The different isomer groups of atracurium have different pharmacokinetics, the trans-trans group having the highest clearance (1440 ml.min-1) and the cis-cis group the lowest (499 ml.min-1).	Atracurium	31-41	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
9349062-13	1997	The different isomer groups of atracurium have different pharmacokinetics, the trans-trans group having the highest clearance (1440 ml.min-1) and the cis-cis group the lowest (499 ml.min-1).	Atracurium	31-41	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
9349062-14	1997	The clearance of cisatracurium (425 ml.min-1) is less than that of cis-cis atracurium and its elimination half-life is longer (34.9 min and 21.9 min, respectively).	cisatracurium	17-30	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
9293354-3	1997	The sensitivity of the aortic-cardiac baroreflex was determined with a approximately 15 mmHg elevation in mean arterial pressure (MAP) induced by steady-state infusion of 30 to 97 micrograms.min-1 phenylephrine (PE) combined with approximately 13 mmHg lower body negative pressure (LBNP) to counteract central venous pressure elevations, and 17-19 mmHg neck pressure (NP) to offset increases in carotid sinus transmural pressure.	Phenylephrine	197-210	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
9458458-4	1997	Prostacyclin was nebulized with 81.min-1 of oxygen and administered in doses increasing from 15 to 50 ng.kg-1.min-1 via a facemask.	Epoprostenol	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
9458458-4	1997	Prostacyclin was nebulized with 81.min-1 of oxygen and administered in doses increasing from 15 to 50 ng.kg-1.min-1 via a facemask.	Epoprostenol	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
9458458-5	1997	Eight of these patients also received intravenous prostacyclin in doses of 1 to 5 ng.kg-1.min-1 and nitric oxide in doses of 10 to 100 ppm via a facemask.	Epoprostenol	50-62	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
9284751-6	1997	Clearances (mL.min-1.g-1, means +/- SD) of PTU from maternal to fetal circuits were: 0.229 +/- 0.110, 0.216 +/- 0.065, and 0.170 +/- 0.032; and for transfer of MMI: 0.165 +/- 0.025, 0.232 +/- 0.153, and 0.174 +/- 0.009 (for low doses without, low doses with, and high doses without albumin, respectively).	Propylthiouracil	43-46	CD59 molecule (CD59 blood group)	Homo sapiens	15-20
9276743-1	1997	Protectin (CD59), a glycosylphosphatidylinositol-anchored cell membrane glycoprotein, is differentially expressed on melanocytic cells and represents the main restriction factor of C-mediated lysis of melanoma cells.	Glycosylphosphatidylinositols	20-48	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
9276743-3	1997	SDS-PAGE analysis showed that the molecular components of sCD59 are similar to those of cellular CD59 expressed by melanoma cells.	Sodium Dodecyl Sulfate	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	59-63
9347472-11	1997	Coeliac axis injection of the NO donor S-nitroso-N-acetyl-penicillamine (SNAP) decreased phasic pyloric activity (from 330 +/- 35 to 148 +/- 21 mmHg min-1 after SNAP 5 micrograms, P < 0.01).	S-Nitroso-N-Acetylpenicillamine	39-71	CD59 molecule (CD59 blood group)	Homo sapiens	149-154
9282948-10	1997	Additional in situ brain perfusion experiments identified a saturable component contributing to CNS entry of [125I-Tyr1]biphalin, which could be described by Michaelis-Menten kinetics with a Km of 2.6 +/- 4.8 microM, Vmax of 14.6 +/- 2.89 pmol(-1) x min(-1) x g(-1), and Kd of 0.568 +/- 0.157 microl x min(-1) x g(-1).	[125i-tyr1]biphalin	109-128	CD59 molecule (CD59 blood group)	Homo sapiens	250-256
9282948-10	1997	Additional in situ brain perfusion experiments identified a saturable component contributing to CNS entry of [125I-Tyr1]biphalin, which could be described by Michaelis-Menten kinetics with a Km of 2.6 +/- 4.8 microM, Vmax of 14.6 +/- 2.89 pmol(-1) x min(-1) x g(-1), and Kd of 0.568 +/- 0.157 microl x min(-1) x g(-1).	[125i-tyr1]biphalin	109-128	CD59 molecule (CD59 blood group)	Homo sapiens	302-308
9447547-3	1997	KCl using a flow rate of 4 ml min-1.	Potassium Chloride	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
9347472-11	1997	Coeliac axis injection of the NO donor S-nitroso-N-acetyl-penicillamine (SNAP) decreased phasic pyloric activity (from 330 +/- 35 to 148 +/- 21 mmHg min-1 after SNAP 5 micrograms, P < 0.01).	S-Nitroso-N-Acetylpenicillamine	73-77	CD59 molecule (CD59 blood group)	Homo sapiens	149-154
9347472-16	1997	Central nervous administration of L-NAME caused modest enhancement of phasic pyloric activity (248 +/- 31 to 283 +/- 32 mmHg min-1 P < 0.05) and pyloric tone (2.6 +/- 0.5 to 3.7 +/- 0.7 mmHg, P < 0.05).	NG-Nitroarginine Methyl Ester	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
18636517-9	1997	Overall, it appears that resting Mycobacterium E3 cells metabolizing ethene at 24 degrees C have, using Blackman biokinetics, a maximum specific degradation rate, v(max), of 10.2 nmol C(2)H(4) mg(-1) CDW min(-1), and an affinity coefficient, K(aff.g), expressed in equilibrium gas concentration units, of 61.9 ppm, when H is assumed equal to 8.309.	ethylene	69-75	CD59 molecule (CD59 blood group)	Homo sapiens	204-210
9286945-8	1997	Study design did not control for amiodarone, which was initiated for arrhythmias in 12 patients and associated with greater improvement in cardiac index (1.8 to 3.2 L min(-1) x m(-2) late on amiodarone versus 2.0 to 2.6 L x min(-1) x m(-2), P<.05).	Amiodarone	33-43	CD59 molecule (CD59 blood group)	Homo sapiens	167-173
9286886-10	1997	The median remifentanil rate for successful analgesia was 0.125 microg x kg(-1) x min(-1) (range, 0.05-0.23 microg x kg(-1) x min(-1)), and the median number of 2-mg morphine boluses used was 2 (range, 0-5 boluses).	Remifentanil	11-23	CD59 molecule (CD59 blood group)	Homo sapiens	82-88
21639331-3	1997	The background due to diffusion of water from the air was normally in the range 0.3-0.9 mug of water min(-1) depending on environmental humidity.	Water	35-40	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
21639331-3	1997	The background due to diffusion of water from the air was normally in the range 0.3-0.9 mug of water min(-1) depending on environmental humidity.	Water	95-100	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
9286886-14	1997	CONCLUSIONS: Remifentanil provided safe and effective postoperative analgesia when administered at a final rate of 0.05-0.23 microg x kg(-1) x min(-1) in the immediate postextubation period.	Remifentanil	13-25	CD59 molecule (CD59 blood group)	Homo sapiens	143-149
9286888-4	1997	If patients had not lost consciousness, 2 mg x kg(-1) x min(-1) thiopental was administered until LOC was achieved.	Thiopental	64-74	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
9235917-3	1997	To elucidate the role of membrane lipids for signal transduction via GPI-anchored proteins, we studied the influence of reduced cellular cholesterol content on calcium signaling via GPI-anchored CD59 and CD48 in Jurkat T cells.	Calcium	160-167	CD59 molecule (CD59 blood group)	Homo sapiens	195-199
9278196-4	1997	RESULTS: Single dose felbamate pharmacokinetic parameters differed between young and elderly subjects; compared with young subjects, elderly subjects had lower mean clearance (31.2 vs 25.1 ml min(-1); 90% CI -11.4 to -0.9; P = 0.02) and a trend towards a greater half-life (18.6 vs 21.0 h; 90% CI -0.6 to 5.4; P = 0.11).	Felbamate	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	192-198
9224737-5	1997	The enzyme purified in the presence of both L-Arg and H4B is highly active, with a Vmax of approximately 800 nmol NO min(-1) mg(-1) and a Km for L-Arg of 22 microM.	Arginine	44-49	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
9224737-5	1997	The enzyme purified in the presence of both L-Arg and H4B is highly active, with a Vmax of approximately 800 nmol NO min(-1) mg(-1) and a Km for L-Arg of 22 microM.	Arginine	145-150	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
9298775-4	1997	Mean maximal oxygen uptake was 51.3 +/- 2.3 ml x kg(-1) x min(-1) at T1 and was at the same level at T2.	Oxygen	13-19	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
9301387-6	1997	Compared with placebo, in the domperidone group there were larger changes in VEinst (0.30 vs 0.55 litre min-1 (P = 0.05) and VT/TI (8.5 vs 26.6 ml s-1 (P = 0.02)) from respective baselines.	Domperidone	30-41	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
9253564-5	1997	A remifentanil post-operative infusion initiated during emergence was titrated in the recovery room for 30 min, at which time 14% of patients had a pain score of 2 and 86% had pain scores of 0 or 1 (0 = no pain; 1 = mild pain; 2 = moderate pain; 3 = severe pain), at a mean infusion rate of 0.086 microgram kg-1 min-1.	Remifentanil	2-14	CD59 molecule (CD59 blood group)	Homo sapiens	312-317
9204953-3	1997	Removal of the lipid-linked complement regulatory proteins CD59 and decay-accelerating factor (DAF) by treatment of the cells with phosphatidylinositol-specific phospholipase C (PIPLC) resulted in increased C3b and C5b-9 deposition on the cells and a slight increase in cell death.	Phosphatidylinositols	131-151	CD59 molecule (CD59 blood group)	Homo sapiens	59-63
9251504-2	1997	Toborinone increased cardiac index (CI) and stroke volume index (SVI) dose-dependently, with significant increases at 10 and 15 micrograms.kg-1.min-1.	toborinone	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
9251504-7	1997	T-wave amplitude on electrocardiaogram (ECG) and oxygen partial pressure in arterial blood decreased at 10 and 15 micrograms.kg-1.min-1.	Oxygen	49-55	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
9245824-6	1997	The apparent Km for palmitate was 97.8 microM and the Vmax was 19.3 nmol min-1 (mg protein)-1.	Palmitates	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	73-93
9185710-8	1997	Treatment of DU 145 and PC3 cells with phosphatidylinositol-specific phospholipase C caused a significant decrease of CD59 expression indicating that the CD59 expressed by prostate cancer cells is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) linkage.	Phosphatidylinositols	39-59	CD59 molecule (CD59 blood group)	Homo sapiens	118-122
9185710-8	1997	Treatment of DU 145 and PC3 cells with phosphatidylinositol-specific phospholipase C caused a significant decrease of CD59 expression indicating that the CD59 expressed by prostate cancer cells is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) linkage.	Phosphatidylinositols	39-59	CD59 molecule (CD59 blood group)	Homo sapiens	154-158
9185710-8	1997	Treatment of DU 145 and PC3 cells with phosphatidylinositol-specific phospholipase C caused a significant decrease of CD59 expression indicating that the CD59 expressed by prostate cancer cells is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) linkage.	Glycosylphosphatidylinositols	233-261	CD59 molecule (CD59 blood group)	Homo sapiens	154-158
9185710-8	1997	Treatment of DU 145 and PC3 cells with phosphatidylinositol-specific phospholipase C caused a significant decrease of CD59 expression indicating that the CD59 expressed by prostate cancer cells is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) linkage.	Glycosylphosphatidylinositols	263-266	CD59 molecule (CD59 blood group)	Homo sapiens	154-158
9185710-10	1997	We conclude that malignant and benign human prostate cells express CD59 that is GPI-linked to the cell surface and that CD59 may regulate the immunological response to cancerous prostate cells by protecting the cells from the cytolytic activity of complement.	Glycosylphosphatidylinositols	80-83	CD59 molecule (CD59 blood group)	Homo sapiens	67-71
9208037-2	1997	At lower doses (< 100 micrograms kg-1 min-1), adenosine has shown to have an analgesic effect.	Adenosine	49-58	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
9208037-10	1997	When adenosine was infused (84 +/- 7 micrograms kg-1 min-1.)	Adenosine	5-14	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
9227629-3	1997	Five days of LPD increased in vitro 1-OHase activity in young (97.3 +/- 13.5 vs. 49.7 +/- 6.8 pg.mg protein-1.5 min-1, P < 0.005) but not adult (42.3 +/- 5.37 vs. 41.2 +/- 8.9) rats.	prolinamide	13-16	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
9333327-1	1997	The ability of low dose dopamine (1-3 micrograms x kg-1 x min-1) to cause selective renal vasodilation, to increase glomerular filtration rate, urine output, and natriuresis, is intuitively considered favourable.	Dopamine	24-32	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
9205824-11	1997	Compared with placebo or zamifenacin, pulse rate fell following hyoscine administration (9 beats min-1, P < 0.01).	Scopolamine	64-72	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
9215021-4	1997	Rocuronium 0.06 (infants) and 0.09 (children) mg kg-1 min-1 was given i.v.	Rocuronium	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
9183605-5	1997	Most dobutamine stress protocols start at an infusion rate of 5 micrograms.kg-1.min-1 and increase to a peak dose of 40 or 50 micrograms.kg-1.min-1; to further increase heart rate, a bolus injection of 0.25-1.0 mg atropine is added.	Dobutamine	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
9298775-5	1997	At T3 and T4 maximal oxygen uptake was increased to 53.8 +/- 2.7 and 53.5 +/- 2.9 ml x kg(-1) x min(-1) (p < 0.05), respectively.	Oxygen	21-27	CD59 molecule (CD59 blood group)	Homo sapiens	96-102
9180633-4	1997	The increased arterial plasma epinephrine levels appeared to be due to a higher total body epinephrine spillover rate in the hypertensive subjects (0.23 +/- 0.02 nmol.min-1.m-2) than the normotensive subjects (0.18 +/- 0.01) (P < .05) and not to a decreased plasma clearance of epinephrine.	Epinephrine	30-41	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
9183619-7	1997	Dobutamine is infused at low rates of 2.5 to 20 micrograms.kg-1.min-1 to detect myocardial viability.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
9212343-11	1997	x mg-1 protein x min-1) which was completely inhibited by 50 mM pyridine.	pyridine	64-72	CD59 molecule (CD59 blood group)	Homo sapiens	17-22
9229292-6	1997	isoproterenol: delta P/D 2.07 +/- 1.36 vs 2.18 +/- 1.42 mm Hg/mm; delta Vcfc 1.55 +/- 0.33 vs 1.40 +/- 0.38 square root of min-1 x %/ms), indicating an unchanged inotropic effect mediated by the postsynaptic beta-receptor/effector system.	Isoproterenol	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
9223888-8	1997	Inhalation of 3 l.min-1 oxygen via a mask is sufficient to prevent such postoperative hypoxemia.	Oxygen	24-30	CD59 molecule (CD59 blood group)	Homo sapiens	18-23
9192316-9	1997	The average rate of oxygen uptake over the quadriceps muscle at maximal work, 353 ml min-1 kg-1, corresponded to a Krebs cycle rate of 4.6 mumol min-1 g-1.	Oxygen	20-26	CD59 molecule (CD59 blood group)	Homo sapiens	85-95
9192316-9	1997	The average rate of oxygen uptake over the quadriceps muscle at maximal work, 353 ml min-1 kg-1, corresponded to a Krebs cycle rate of 4.6 mumol min-1 g-1.	krebs	115-120	CD59 molecule (CD59 blood group)	Homo sapiens	85-95
9223891-3	1997	The prophylactic intravenous diltiazem infusion (1.0 micrograms.kg-1.min-1) was started immediately after induction of general anesthesia or epidural analgesia and continued until the end of operation.	Diltiazem	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
9198259-6	1997	The physical performance during an ergometer test corresponded to a maximal oxygen consumption of 21 ml/kg-1 x min-1.	Oxygen	76-82	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
9165972-3	1997	The delivery of oxygen at 21.min-1 via nasal cannulae was shown to be superior to a method which directed oxygen from under the surgical drapes.	Oxygen	16-22	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
9159566-1	1997	AIMS: The purpose of the present study was to define the dose-response relationship between exogenous dopamine and systemic haemodynamics, renal haemodynamics, and renal excretory function at infusion rates in the range 0 to 12.5 microg kg(-1) min(-1) in normal volunteers.	Dopamine	102-110	CD59 molecule (CD59 blood group)	Homo sapiens	244-250
9176196-5	1997	However, net increase in 2-DG uptake activity after acute insulin (100 nM) stimulation was 355 +/- 56 pmol.mg protein-1.min-1 in control vs. 198 +/- 41 pmol.mg protein-1.min-1 in GO-pretreated cells (P < 0.05).	Deoxyglucose	25-29	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
9176196-5	1997	However, net increase in 2-DG uptake activity after acute insulin (100 nM) stimulation was 355 +/- 56 pmol.mg protein-1.min-1 in control vs. 198 +/- 41 pmol.mg protein-1.min-1 in GO-pretreated cells (P < 0.05).	Deoxyglucose	25-29	CD59 molecule (CD59 blood group)	Homo sapiens	170-175
9175963-5	1997	infusion of 10 mg min-1 was studied in a crossover, randomized, double-blind study in 12 volunteers previously acquainted with the CNS effects of lignocaine.	Lidocaine	146-156	CD59 molecule (CD59 blood group)	Homo sapiens	18-23
9159566-9	1997	Sodium clearance (CL(Na)) and CL(Li) were elevated with the four lowest doses but increased further from 7.5 microg kg(-1) min(-1) onwards.	Sodium	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	123-129
9159566-12	1997	Fractional distal reabsorption of sodium (FDR(Na) = (CL(Li)-CL(Na))/CL(Li)) decreased with all doses, reaching its nadir with 7.5 microg kg(-1) min(-1) [from 95.9 (94.6-97.2) % with placebo to 91.5 (90.0-93.0) % (P<0.01)] whereafter a flat dose-response curve was observed.	Sodium	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	144-150
9159566-13	1997	CONCLUSIONS: In conclusion, the renal vasodilating effect of dopamine was maximal with 3 microg kg(-1) min(-1).	Dopamine	61-69	CD59 molecule (CD59 blood group)	Homo sapiens	103-109
9185458-3	1997	In PGE1 group, PGE1 was infused throughout surgery at a rate of 0.02 microgram kg-1 min-1.	Alprostadil	3-7	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
9225074-7	1997	Both protein kinase C inhibitors studied (staurosporine and CGP 41251) exhibited variable effects on cell surface antigen (HLA, ICAM-1, CD59) expression, suggesting complex interactions between PKC-dependent and -independent mechanisms in the regulation of surface antigen expression in these cell lines.	Staurosporine	42-55	CD59 molecule (CD59 blood group)	Homo sapiens	136-140
9185458-3	1997	In PGE1 group, PGE1 was infused throughout surgery at a rate of 0.02 microgram kg-1 min-1.	Alprostadil	15-19	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
9185464-3	1997	In the diltiazem group continuous intravenous infusion of diltiazem (1-3mcg.kg-1.min-1) was started when the patient"s heart rate remained over 110.min-1 without any predisposing factor.	Diltiazem	58-67	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
9185464-3	1997	In the diltiazem group continuous intravenous infusion of diltiazem (1-3mcg.kg-1.min-1) was started when the patient"s heart rate remained over 110.min-1 without any predisposing factor.	Diltiazem	58-67	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
9185466-2	1997	As the vasodilator, we used PGE1 at the dose of 0.02-0.05 microgram.kg-1.min-1.	Alprostadil	28-32	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
9135180-14	1997	An initial remifentanil infusion rate of 0.1 microgram.kg-1.min-1 titrated to individual need provided postoperative pain relief in the presence of adequate respiration in 71% of patients.	Remifentanil	11-23	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
9232684-5	1997	The mean peripheral-chemoreflex sensitivity of 11.5 (5.2) L min-1 mmHg-1 at an iso-oxic PO2 of 40 was significantly greater than 3.0 (1.3), 2.7 (1.2) and 2.4 (1.2) at 60, 80 and 100, respectively.	PO-2	88-91	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
9142883-5	1997	However, turnover of glutamine determined with [3,4-3H]glutamine (6.14 +/- 0.54 micromol x kg(-1) x min(-1)) exceeded that determined with [U-14C]glutamine (5.72 +/- 0.541 micromol x kg(-1) x min(-1); P < 0.03), which in turn exceeded that determined with [2-15N]glutamine (4.67 +/- 0.39 micromol x kg(-1) x min(-1), P < 0.01).	Glutamine	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
9142883-5	1997	However, turnover of glutamine determined with [3,4-3H]glutamine (6.14 +/- 0.54 micromol x kg(-1) x min(-1)) exceeded that determined with [U-14C]glutamine (5.72 +/- 0.541 micromol x kg(-1) x min(-1); P < 0.03), which in turn exceeded that determined with [2-15N]glutamine (4.67 +/- 0.39 micromol x kg(-1) x min(-1), P < 0.01).	Glutamine	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	192-198
9142883-5	1997	However, turnover of glutamine determined with [3,4-3H]glutamine (6.14 +/- 0.54 micromol x kg(-1) x min(-1)) exceeded that determined with [U-14C]glutamine (5.72 +/- 0.541 micromol x kg(-1) x min(-1); P < 0.03), which in turn exceeded that determined with [2-15N]glutamine (4.67 +/- 0.39 micromol x kg(-1) x min(-1), P < 0.01).	Glutamine	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	192-198
9085949-3	1997	After surgery, remifentanil was infused at 1.0 microg x kg(-1) x min(-1) in all patients.	Remifentanil	15-27	CD59 molecule (CD59 blood group)	Homo sapiens	65-71
9135180-18	1997	Remifentanil can be administered as a postoperative analgesic agent at a starting dose of 0.1 microgram-.kg-1.min-1; however, it should only be used in the presence of adequate supervision and monitoring of the patient.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
9124918-4	1997	Dobutamine infusion was started at a rate of 5 microg x kg(-1) x min(-1) and increased to 10 and 20 microg x kg(-1) x min(-1) at 15-minute intervals.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	65-71
9113345-9	1997	The Eadie-Hofstee plot of DMO N-demethylation was consistent with single-enzyme Michaelis-Menten kinetics (Vmax varying from 3.3 to 6.8 nmol mg-1 min-1, K(m) from 231 to 322 microM).	Nitrogen	30-31	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
9135350-3	1997	cannula and breathed oxygen 5 litre min-1.	Oxygen	21-27	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
9176040-9	1997	The 20 ng min-1 kg-1 dose increased the urinary sodium excretion and urinary flow rate compared with the effects of placebo.	Sodium	48-54	CD59 molecule (CD59 blood group)	Homo sapiens	10-20
9176040-17	1997	We conclude, that the urodilatin dose of 20 ng min-1 kg-1 of body weight was most efficacious in this short-term infusion study, and that it had potent natriuretic and diuretic qualities, probably due to stimulation of the glomerular filtration rate and inhibition of sodium reabsorption in the distal part of the nephron.	Ularitide	22-32	CD59 molecule (CD59 blood group)	Homo sapiens	47-57
9129897-8	1997	Digoxin had a pronounced and rapid effect on heart rate, which was already significant at 2 h; 104.6 +/- 20.9 beats.min-1 vs 116.8 +/- 22.5 beats.min-1 (P = 0.0001).	Digoxin	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
9129897-8	1997	Digoxin had a pronounced and rapid effect on heart rate, which was already significant at 2 h; 104.6 +/- 20.9 beats.min-1 vs 116.8 +/- 22.5 beats.min-1 (P = 0.0001).	Digoxin	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
9176121-1	1997	Non-lethal complement (C) attack on K562 cells has been shown to induce a transient resistance to lethal amounts of C. We have previously shown that incubation of K562 with phorbol 12-myristate 13-acetate (PMA) caused an increase in both CD59 expression and resistance to C killing and we were interested to examine whether non-lethal C attack caused a similar effect.	Tetradecanoylphorbol Acetate	173-204	CD59 molecule (CD59 blood group)	Homo sapiens	238-242
9176121-1	1997	Non-lethal complement (C) attack on K562 cells has been shown to induce a transient resistance to lethal amounts of C. We have previously shown that incubation of K562 with phorbol 12-myristate 13-acetate (PMA) caused an increase in both CD59 expression and resistance to C killing and we were interested to examine whether non-lethal C attack caused a similar effect.	Tetradecanoylphorbol Acetate	206-209	CD59 molecule (CD59 blood group)	Homo sapiens	238-242
9104876-4	1997	Pretraining, the intensity effect on glucose kinetics was evident with rates of appearance (R(a); 5.84 +/- 0.23 vs. 4.73 +/- 0.19 mg x kg(-1) x min(-1)), disappearance (R(d); 5.78 +/- 0.19 vs. 4.73 +/- 0.19 mg x kg(-1) x min(-1) x min(-1)), oxidation (R(ox); 5.36 +/- 0.15 vs. 3.41 +/- 0.23 mg x kg(-1) x min(-1)), and metabolic clearance (7.03 +/- 0.56 vs. 5.20 +/- 0.28 ml x kg(-1) x min(-1)) of glucose being significantly greater (P < or = 0.05) in the 65% than the 45% VO2peak trial.	Glucose	37-44	CD59 molecule (CD59 blood group)	Homo sapiens	144-150
9104876-4	1997	Pretraining, the intensity effect on glucose kinetics was evident with rates of appearance (R(a); 5.84 +/- 0.23 vs. 4.73 +/- 0.19 mg x kg(-1) x min(-1)), disappearance (R(d); 5.78 +/- 0.19 vs. 4.73 +/- 0.19 mg x kg(-1) x min(-1) x min(-1)), oxidation (R(ox); 5.36 +/- 0.15 vs. 3.41 +/- 0.23 mg x kg(-1) x min(-1)), and metabolic clearance (7.03 +/- 0.56 vs. 5.20 +/- 0.28 ml x kg(-1) x min(-1)) of glucose being significantly greater (P < or = 0.05) in the 65% than the 45% VO2peak trial.	Glucose	37-44	CD59 molecule (CD59 blood group)	Homo sapiens	221-227
9104876-4	1997	Pretraining, the intensity effect on glucose kinetics was evident with rates of appearance (R(a); 5.84 +/- 0.23 vs. 4.73 +/- 0.19 mg x kg(-1) x min(-1)), disappearance (R(d); 5.78 +/- 0.19 vs. 4.73 +/- 0.19 mg x kg(-1) x min(-1) x min(-1)), oxidation (R(ox); 5.36 +/- 0.15 vs. 3.41 +/- 0.23 mg x kg(-1) x min(-1)), and metabolic clearance (7.03 +/- 0.56 vs. 5.20 +/- 0.28 ml x kg(-1) x min(-1)) of glucose being significantly greater (P < or = 0.05) in the 65% than the 45% VO2peak trial.	Glucose	37-44	CD59 molecule (CD59 blood group)	Homo sapiens	221-227
9104876-4	1997	Pretraining, the intensity effect on glucose kinetics was evident with rates of appearance (R(a); 5.84 +/- 0.23 vs. 4.73 +/- 0.19 mg x kg(-1) x min(-1)), disappearance (R(d); 5.78 +/- 0.19 vs. 4.73 +/- 0.19 mg x kg(-1) x min(-1) x min(-1)), oxidation (R(ox); 5.36 +/- 0.15 vs. 3.41 +/- 0.23 mg x kg(-1) x min(-1)), and metabolic clearance (7.03 +/- 0.56 vs. 5.20 +/- 0.28 ml x kg(-1) x min(-1)) of glucose being significantly greater (P < or = 0.05) in the 65% than the 45% VO2peak trial.	Glucose	37-44	CD59 molecule (CD59 blood group)	Homo sapiens	221-227
9104876-4	1997	Pretraining, the intensity effect on glucose kinetics was evident with rates of appearance (R(a); 5.84 +/- 0.23 vs. 4.73 +/- 0.19 mg x kg(-1) x min(-1)), disappearance (R(d); 5.78 +/- 0.19 vs. 4.73 +/- 0.19 mg x kg(-1) x min(-1) x min(-1)), oxidation (R(ox); 5.36 +/- 0.15 vs. 3.41 +/- 0.23 mg x kg(-1) x min(-1)), and metabolic clearance (7.03 +/- 0.56 vs. 5.20 +/- 0.28 ml x kg(-1) x min(-1)) of glucose being significantly greater (P < or = 0.05) in the 65% than the 45% VO2peak trial.	Glucose	37-44	CD59 molecule (CD59 blood group)	Homo sapiens	221-227
9128034-4	1997	After 15 minutes of high flow anesthesia, the total gas flow was reduced to 300 ml.min-1 of oxygen, 300 ml.min-1 of nitrous oxide or reduced to 400 ml.min-1 of oxygen, 200 ml.min-1 of nitrous oxide in the low flow anesthesia group.	Oxygen	92-98	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
9135191-5	1997	After equilibration total flow were reduced to 500 ml.min-1; at these flows the initial decline in end-expired agent concentration was minimal with desflurane, intermediate with sevoflurane and greatest with isoflurane.	Sevoflurane	178-189	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
9135191-5	1997	After equilibration total flow were reduced to 500 ml.min-1; at these flows the initial decline in end-expired agent concentration was minimal with desflurane, intermediate with sevoflurane and greatest with isoflurane.	Isoflurane	208-218	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
9128034-4	1997	After 15 minutes of high flow anesthesia, the total gas flow was reduced to 300 ml.min-1 of oxygen, 300 ml.min-1 of nitrous oxide or reduced to 400 ml.min-1 of oxygen, 200 ml.min-1 of nitrous oxide in the low flow anesthesia group.	Nitrous Oxide	116-129	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
9128034-4	1997	After 15 minutes of high flow anesthesia, the total gas flow was reduced to 300 ml.min-1 of oxygen, 300 ml.min-1 of nitrous oxide or reduced to 400 ml.min-1 of oxygen, 200 ml.min-1 of nitrous oxide in the low flow anesthesia group.	Nitrous Oxide	116-129	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
9128034-4	1997	After 15 minutes of high flow anesthesia, the total gas flow was reduced to 300 ml.min-1 of oxygen, 300 ml.min-1 of nitrous oxide or reduced to 400 ml.min-1 of oxygen, 200 ml.min-1 of nitrous oxide in the low flow anesthesia group.	Nitrous Oxide	116-129	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
9054419-1	1997	Human erythrocyte CD59 contains N- and O-glycans and a glycosylphosphatidylinositol (GPI) anchor, all of which have been analyzed in this study.	n- and o-glycans	32-48	CD59 molecule (CD59 blood group)	Homo sapiens	18-22
9054419-1	1997	Human erythrocyte CD59 contains N- and O-glycans and a glycosylphosphatidylinositol (GPI) anchor, all of which have been analyzed in this study.	Glycosylphosphatidylinositols	55-83	CD59 molecule (CD59 blood group)	Homo sapiens	18-22
9054419-1	1997	Human erythrocyte CD59 contains N- and O-glycans and a glycosylphosphatidylinositol (GPI) anchor, all of which have been analyzed in this study.	Glycosylphosphatidylinositols	85-88	CD59 molecule (CD59 blood group)	Homo sapiens	18-22
9054419-10	1997	Inspection of a molecular model of CD59, based on the NMR solution structure of the extracellular domain and the structural data from this study, suggested several roles for the glycans, including spacing and orienting CD59 on the cell surface and protecting the molecule from proteases.	Polysaccharides	178-185	CD59 molecule (CD59 blood group)	Homo sapiens	35-39
9054419-10	1997	Inspection of a molecular model of CD59, based on the NMR solution structure of the extracellular domain and the structural data from this study, suggested several roles for the glycans, including spacing and orienting CD59 on the cell surface and protecting the molecule from proteases.	Polysaccharides	178-185	CD59 molecule (CD59 blood group)	Homo sapiens	219-223
9106069-2	1997	Sodium cromoglycate was extracted from urine on a 100-mg phenyl cartridge (Isolute, Jones Chromatography) and then quantified on a 25-cm C8 Spherisorb 5 microns stationary phase with a mobile phase of methanol-0.045 M phosphate buffer-0.05 M dodecyl triethyl ammonium phosphate (550:447.6:2.4, v/v) pH 2.3, at 0.85 ml min-1 using nedocromil sodium as an internal standard and UV detection at 238 nm.	Cromolyn Sodium	0-19	CD59 molecule (CD59 blood group)	Homo sapiens	318-323
9079155-2	1997	Adenosine infusion was given intravenously to 12 volunteers in the antecubital vein with infusion rates increasing from 20 to 100 micrograms kg-1 min-1.	Adenosine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
9124550-3	1997	Although infusion of glutamine increased plasma glutamine concentration and turnover only threefold (from 0.63 +/- 0.03 to 1.95 +/- 0.10 mmol/l and from 5.43 +/- 0.24 to 14.85 +/- 0.66 micromol x kg(-1) x min(-1), respectively; P < 0.001), formation of glucose from glutamine increased sevenfold from 0.55 +/- 0.03 to 3.74 +/- 0.28 micromol x kg(-1) x min(-1) (P < 0.001).	Glutamine	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	205-211
9124550-3	1997	Although infusion of glutamine increased plasma glutamine concentration and turnover only threefold (from 0.63 +/- 0.03 to 1.95 +/- 0.10 mmol/l and from 5.43 +/- 0.24 to 14.85 +/- 0.66 micromol x kg(-1) x min(-1), respectively; P < 0.001), formation of glucose from glutamine increased sevenfold from 0.55 +/- 0.03 to 3.74 +/- 0.28 micromol x kg(-1) x min(-1) (P < 0.001).	Glutamine	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	355-361
9124550-4	1997	Formation of glucose from alanine was also stimulated (0.52 +/- 0.05 vs. 0.75 +/- 0.04 micromol x kg(-1) x min(-1); P < 0.001) in the absence of a change in plasma alanine concentration.	Glucose	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
9124550-4	1997	Formation of glucose from alanine was also stimulated (0.52 +/- 0.05 vs. 0.75 +/- 0.04 micromol x kg(-1) x min(-1); P < 0.001) in the absence of a change in plasma alanine concentration.	Alanine	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
9124550-5	1997	Furthermore, glutamine infusion decreased its own de novo synthesis (4.55 +/- 0.22 vs. 2.81 +/- 0.62 micromol x kg(-1) x min(-1);P < 0.02) while increasing that of alanine (2.82 +/- 0.32 vs. 3.56 +/- 0.32 micromol x kg(-1) x min(-1); P < 0.002).	Glutamine	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	121-127
9124550-5	1997	Furthermore, glutamine infusion decreased its own de novo synthesis (4.55 +/- 0.22 vs. 2.81 +/- 0.62 micromol x kg(-1) x min(-1);P < 0.02) while increasing that of alanine (2.82 +/- 0.32 vs. 3.56 +/- 0.32 micromol x kg(-1) x min(-1); P < 0.002).	Glutamine	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	228-234
9052321-8	1997	The mivacurium infusion requirement for the group receiving the pancuronium supplementation was 2.77 +/- 1.38 micrograms.kg-1.min-1 (mean +/- SD), which represented a 49% decrease compared with the group that used mivacurium alone which required an infusion rate of 5.43 +/- 1.85 micrograms.kg-1.min-1.	Mivacurium	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
9052321-8	1997	The mivacurium infusion requirement for the group receiving the pancuronium supplementation was 2.77 +/- 1.38 micrograms.kg-1.min-1 (mean +/- SD), which represented a 49% decrease compared with the group that used mivacurium alone which required an infusion rate of 5.43 +/- 1.85 micrograms.kg-1.min-1.	Pancuronium	64-75	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
9052321-8	1997	The mivacurium infusion requirement for the group receiving the pancuronium supplementation was 2.77 +/- 1.38 micrograms.kg-1.min-1 (mean +/- SD), which represented a 49% decrease compared with the group that used mivacurium alone which required an infusion rate of 5.43 +/- 1.85 micrograms.kg-1.min-1.	Pancuronium	64-75	CD59 molecule (CD59 blood group)	Homo sapiens	296-301
9091249-5	1997	The antipyrine (phenazone) clearance rate in young subjects was 46.4 +/- 18.5 ml.min-1, remained unaltered during the fourth decade, and declined after 40 years by a rate of 0.34 ml.min-1 per year toward old age (-29%, p < 0.001).	Antipyrine	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
9091249-5	1997	The antipyrine (phenazone) clearance rate in young subjects was 46.4 +/- 18.5 ml.min-1, remained unaltered during the fourth decade, and declined after 40 years by a rate of 0.34 ml.min-1 per year toward old age (-29%, p < 0.001).	Antipyrine	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
9076386-4	1997	The peripheral chemoreflex of 12 healthy controls with similar demographic characteristics was 0.272 +/- 0.201l.min-1.%Sao(2)-1 compared with 0.673 +/- 0.410l.	sao(2)	119-125	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
9088818-5	1997	In the remaining 19, heart rate (HR) and cardiac index (CI) were significantly (P < 0.05) increased from base-line with dopexamine: the HR values with dopexamine differed significantly from those with placebo at the 2 and 4 micrograms kg-1 min-1 dose and at 4 micrograms kg-1 min-1 for CI.	dopexamine	154-164	CD59 molecule (CD59 blood group)	Homo sapiens	243-248
9076386-5	1997	min-1.%Sao(2)-1 (P < 0.0001) in the chronic heart failure patients.	sao(2)	7-13	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
9088818-5	1997	In the remaining 19, heart rate (HR) and cardiac index (CI) were significantly (P < 0.05) increased from base-line with dopexamine: the HR values with dopexamine differed significantly from those with placebo at the 2 and 4 micrograms kg-1 min-1 dose and at 4 micrograms kg-1 min-1 for CI.	dopexamine	154-164	CD59 molecule (CD59 blood group)	Homo sapiens	279-284
9076391-13	1997	CONCLUSION: In combination with transoesophageal Doppler echocardiography, a short-lasting adenosine infusion at a rate of 140 micrograms.kg-1.min-1 seems to be preferable to an adenosine bolus and dipyridamole infusion.	Adenosine	91-100	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
9088818-6	1997	Systemic vascular resistance index (SVRI) fell significantly in both groups: the reduction was significantly greater with dopexamine 4 micrograms kg-1 min-1 than with the corresponding infusion of placebo.	dopexamine	122-132	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
9074995-8	1997	Examples from a recording of a 13-wk-old full-term infant obtained by using the system give evaporative water loss rates of approximately 0.02 mgH2O.cm-2.min-1 for normothermic baseline conditions and values up to 0.4 mgH2O.cm-2.	Water	104-109	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
9118935-6	1997	Mean oxygen consumption standing still at the start of the trial was 0.421 min-1 (SD = 0.101 min-1, max.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
9118935-6	1997	Mean oxygen consumption standing still at the start of the trial was 0.421 min-1 (SD = 0.101 min-1, max.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
9118935-9	1997	During exercise, the mean oxygen consumption rose to 2.711 min-1 (SD = 0.641 min-1, max = 4.051 min-1) and mean ventilation reached 46.341 min-1 (SD = 15.831 min-1, max = 87.361 min-1) during the fifth minute of exercise.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
9118935-9	1997	During exercise, the mean oxygen consumption rose to 2.711 min-1 (SD = 0.641 min-1, max = 4.051 min-1) and mean ventilation reached 46.341 min-1 (SD = 15.831 min-1, max = 87.361 min-1) during the fifth minute of exercise.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
9118935-9	1997	During exercise, the mean oxygen consumption rose to 2.711 min-1 (SD = 0.641 min-1, max = 4.051 min-1) and mean ventilation reached 46.341 min-1 (SD = 15.831 min-1, max = 87.361 min-1) during the fifth minute of exercise.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
9118935-9	1997	During exercise, the mean oxygen consumption rose to 2.711 min-1 (SD = 0.641 min-1, max = 4.051 min-1) and mean ventilation reached 46.341 min-1 (SD = 15.831 min-1, max = 87.361 min-1) during the fifth minute of exercise.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
9118935-9	1997	During exercise, the mean oxygen consumption rose to 2.711 min-1 (SD = 0.641 min-1, max = 4.051 min-1) and mean ventilation reached 46.341 min-1 (SD = 15.831 min-1, max = 87.361 min-1) during the fifth minute of exercise.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
9118935-9	1997	During exercise, the mean oxygen consumption rose to 2.711 min-1 (SD = 0.641 min-1, max = 4.051 min-1) and mean ventilation reached 46.341 min-1 (SD = 15.831 min-1, max = 87.361 min-1) during the fifth minute of exercise.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
9074995-8	1997	Examples from a recording of a 13-wk-old full-term infant obtained by using the system give evaporative water loss rates of approximately 0.02 mgH2O.cm-2.min-1 for normothermic baseline conditions and values up to 0.4 mgH2O.cm-2.	mgh2o	143-148	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
9074995-8	1997	Examples from a recording of a 13-wk-old full-term infant obtained by using the system give evaporative water loss rates of approximately 0.02 mgH2O.cm-2.min-1 for normothermic baseline conditions and values up to 0.4 mgH2O.cm-2.	mgh2o	218-223	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
9165757-5	1997	Using p-tosyl-L-arginine methyl ester as substrate, the catalyst specific activity, KMapp and kcat/KMapp were 17.8 U ml-1 of beads, 3.60 and 21.0 mM-1 min-1, respectively, for trypsin-APC as compared with 24.5 U ml-1 of beads, 3.77 and 20.3 mM-1 min-1, respectively, for trypsin-SAPC.	Tosylarginine Methyl Ester	6-37	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
9073605-5	1997	Bimolecular rate constants of inhibition (ki) for NTE ranged from 0.571 for L-ala-CS to 17.7 mM-1 min-1 for L-norleu-CS (10-min I50 values of 123 and 3.92 microM, respectively).	l-norleu-cs	108-119	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
9165757-5	1997	Using p-tosyl-L-arginine methyl ester as substrate, the catalyst specific activity, KMapp and kcat/KMapp were 17.8 U ml-1 of beads, 3.60 and 21.0 mM-1 min-1, respectively, for trypsin-APC as compared with 24.5 U ml-1 of beads, 3.77 and 20.3 mM-1 min-1, respectively, for trypsin-SAPC.	Tosylarginine Methyl Ester	6-37	CD59 molecule (CD59 blood group)	Homo sapiens	246-251
9034152-5	1997	In addition, removal of the single N-linked glycosylation site at Asn18 of CD59 resulted in an enhancement of complement inhibitory activity.	Nitrogen	35-36	CD59 molecule (CD59 blood group)	Homo sapiens	75-79
21781755-6	1997	The enzymatic activity of 154 +- 16 pmol min(-1) mg(-1) protein was comparable with dextromethorphan-O-demethylation activities of human liver.	dextromethorphan-o	84-102	CD59 molecule (CD59 blood group)	Homo sapiens	41-47
9048549-6	1997	The thermodynamic quantities obtained from the DSC studies in phosphate buffer at pH 7.0 are as follows: t1/2 = 54.7 degrees C (heating rate of 2.34 K min-1), delta H0 = 690 kJ mol-1, and delta Cp = 10.3 kJ mol-1 K-1 which correspondends to a value of delta G0D (20 degrees C) of 53.4 kJ mol-1.	Phosphates	62-71	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
9053451-4	1997	Analysis of 16 CD59 mutants with single, highly nonconservative substitutions suggests that CD59 has a single active site that includes Trp-40, Arg-53, and Glu-56 of the glycosylated, membrane-distal face of the disk-like extra-cellular domain and, possibly, Asp-24 positioned at the edge of the domain.	Tryptophan	136-139	CD59 molecule (CD59 blood group)	Homo sapiens	15-19
9053451-4	1997	Analysis of 16 CD59 mutants with single, highly nonconservative substitutions suggests that CD59 has a single active site that includes Trp-40, Arg-53, and Glu-56 of the glycosylated, membrane-distal face of the disk-like extra-cellular domain and, possibly, Asp-24 positioned at the edge of the domain.	Tryptophan	136-139	CD59 molecule (CD59 blood group)	Homo sapiens	92-96
9053451-4	1997	Analysis of 16 CD59 mutants with single, highly nonconservative substitutions suggests that CD59 has a single active site that includes Trp-40, Arg-53, and Glu-56 of the glycosylated, membrane-distal face of the disk-like extra-cellular domain and, possibly, Asp-24 positioned at the edge of the domain.	Arginine	144-147	CD59 molecule (CD59 blood group)	Homo sapiens	15-19
9053451-4	1997	Analysis of 16 CD59 mutants with single, highly nonconservative substitutions suggests that CD59 has a single active site that includes Trp-40, Arg-53, and Glu-56 of the glycosylated, membrane-distal face of the disk-like extra-cellular domain and, possibly, Asp-24 positioned at the edge of the domain.	Arginine	144-147	CD59 molecule (CD59 blood group)	Homo sapiens	92-96
9036753-7	1997	Glomerular filtration rate changed from 79 +/- 20 to 78 +/- 19 ml/min/1.73 m2 with placebo, and from 85 +/- 21 to 73 +/- 27 ml/min/1.73 m2 with enalapril (p = 0.051).	Enalapril	144-153	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
9053451-4	1997	Analysis of 16 CD59 mutants with single, highly nonconservative substitutions suggests that CD59 has a single active site that includes Trp-40, Arg-53, and Glu-56 of the glycosylated, membrane-distal face of the disk-like extra-cellular domain and, possibly, Asp-24 positioned at the edge of the domain.	Glutamic Acid	156-159	CD59 molecule (CD59 blood group)	Homo sapiens	15-19
9053451-4	1997	Analysis of 16 CD59 mutants with single, highly nonconservative substitutions suggests that CD59 has a single active site that includes Trp-40, Arg-53, and Glu-56 of the glycosylated, membrane-distal face of the disk-like extra-cellular domain and, possibly, Asp-24 positioned at the edge of the domain.	Glutamic Acid	156-159	CD59 molecule (CD59 blood group)	Homo sapiens	92-96
9053451-4	1997	Analysis of 16 CD59 mutants with single, highly nonconservative substitutions suggests that CD59 has a single active site that includes Trp-40, Arg-53, and Glu-56 of the glycosylated, membrane-distal face of the disk-like extra-cellular domain and, possibly, Asp-24 positioned at the edge of the domain.	Aspartic Acid	259-262	CD59 molecule (CD59 blood group)	Homo sapiens	92-96
9031740-13	1997	The selective NPY Y1 receptor antagonist BIBP3226 (100 micrograms kg-1 min-1, i.a.)	BIBP 3226	41-49	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
9052449-5	1997	Of 17 patients with oxygen delivery levels lower than 445 ml min-1 m-2 at 6 h, eight died in hospital.	Oxygen	20-26	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
9055188-9	1997	The renal clearance of articaine is 22.5 +/- 13.9 mL min-1, whereas that of articainic acid is 119.6 +/- 30.1 mL min-1 (P < 0.0001).	Carticaine	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
9043840-3	1997	AIMS: The present study aimed to assess the effects of non-beta-blocker antianginal therapy on dobutamine (up to 40 micrograms.kg-1.min-1)-atropine (up to 1 mg) stress.	Dobutamine	95-105	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
9043840-3	1997	AIMS: The present study aimed to assess the effects of non-beta-blocker antianginal therapy on dobutamine (up to 40 micrograms.kg-1.min-1)-atropine (up to 1 mg) stress.	Atropine	139-147	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
9043849-9	1997	In an initial dose-ranging test, prostaglandin E1 was uptitrated to side effect limit (29 +/- 1 ng.kg-1.min-1).	Alprostadil	33-49	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
9043849-13	1997	After 4 weeks in six patients in group A and in 13 patients in group B, when prostaglandin E1 had been reduced from 15 +/- 2 ng.kg-1.min-1 to 8 +/- 1 ng.kg-1 min-1 increases in cardiac index and decreases in systemic vascular resistance were sustained, and a permanent decrease in pulmonary vascular resistance index was observed in group B.	Alprostadil	77-93	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
9043849-13	1997	After 4 weeks in six patients in group A and in 13 patients in group B, when prostaglandin E1 had been reduced from 15 +/- 2 ng.kg-1.min-1 to 8 +/- 1 ng.kg-1 min-1 increases in cardiac index and decreases in systemic vascular resistance were sustained, and a permanent decrease in pulmonary vascular resistance index was observed in group B.	Alprostadil	77-93	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
9055188-10	1997	The apparent renal clearance of articainic acid glucuronide was 25.4 +/- 12.0 mL min-1.	articainic acid glucuronide	32-59	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
9055188-9	1997	The renal clearance of articaine is 22.5 +/- 13.9 mL min-1, whereas that of articainic acid is 119.6 +/- 30.1 mL min-1 (P < 0.0001).	2-carboxyarticaine	76-91	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
9055188-12	1997	Articainic acid glucuronide is not present in plasma, but has an apparent renal clearance of 25 mL min-1.	articainic acid glucuronide	0-27	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
9110364-4	1997	In red blood cells from individuals homozygous for G at nucleotide position 544 coding for Val-158, the activity of COMT ranged from 0.55-1.03 pmol min-1 mg-1 protein, and in individuals homozygous for A at position 544 coding for Met-158, the activity ranged from 0.21-0.43 pmol min-1 mg-1.	Valine	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	148-158
9059299-9	1997	Median lymph node permeability to iopamidol was 88.5 microliters min-1 ml-1 (range 36.4-198.5 microliters min-1 ml-1).	Iopamidol	34-43	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
9248564-12	1997	Clinical studies have revealed that adenosine administration by bolus injection or by infusion at doses above 70 micrograms x kg-1 x min-1 is associated with pain symptoms from different parts of the body.	Adenosine	36-45	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
9056048-2	1997	METHODS: Non-compartmental pharmacokinetics of a single oral dose (200 mg) of the anti-epileptic agent, lamotrigine, and its main metabolite, lamotrigine N2-glucuronide, were determined for 10 patients with chronic renal failure of mean estimated creatinine clearance 18 ml min-1 and a control group of 11 healthy volunteers, matched for age and gender.	Lamotrigine	104-115	CD59 molecule (CD59 blood group)	Homo sapiens	274-279
9056050-2	1997	METHODS: Meloxicam was administered to subjects with mild (creatinine clearance 41-60 ml min-1) to moderate (20-40 ml min-1) renal impairment compared with normal renal function (> 60 ml min-1).	Meloxicam	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
9056050-2	1997	METHODS: Meloxicam was administered to subjects with mild (creatinine clearance 41-60 ml min-1) to moderate (20-40 ml min-1) renal impairment compared with normal renal function (> 60 ml min-1).	Meloxicam	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
9056050-2	1997	METHODS: Meloxicam was administered to subjects with mild (creatinine clearance 41-60 ml min-1) to moderate (20-40 ml min-1) renal impairment compared with normal renal function (> 60 ml min-1).	Meloxicam	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
9059299-9	1997	Median lymph node permeability to iopamidol was 88.5 microliters min-1 ml-1 (range 36.4-198.5 microliters min-1 ml-1).	Iopamidol	34-43	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
8978323-7	1997	The major new findings in this study are that in healthy humans (1) renal cortical blood flow decreases (basal versus handgrip, 4.4 +/- 0.1 versus 3.5 +/- 0.1 mL.min-1.g-1; P = .008) and renal cortical vascular resistance increases (basal versus handgrip, 17 +/- 1 versus 26 +/- 2 U; P = .01) in response to static handgrip exercise; (2) central command and/or the mechanoreflex contributes importantly to the early decrease in renal blood flow (basal versus handgrip, 4.2 +/- 0.2 versus 3.5 +/- 0.3 mL.min-1.g-1; P = .04) and to the increase in renal cortical vascular resistance (basal versus handgrip, 20 +/- 1 versus 25 +/- 2 U; P = .04); (3) the muscle metaboreflex contributes to further decreases in renal blood flow (basal versus posthandgrip circulatory arrest, 4.3 +/- 0.1 versus 3.5 +/- 0.2 mL.min-1.g-1; P = .002) and increases in renal cortical vascular resistance (basal versus handgrip, 18 +/- 1 versus 25 +/- 3 U; P = .002); and (4) exogenous adenosine activates the muscle metaboreflex producing reflex renal vasoconstriction and decreased renal blood flow, which may implicate endogenous adenosine generated during ischemic exercise as a potential activator of the muscle metaboreflex during ischemic handgrip exercise.	Adenosine	959-968	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
8978323-7	1997	The major new findings in this study are that in healthy humans (1) renal cortical blood flow decreases (basal versus handgrip, 4.4 +/- 0.1 versus 3.5 +/- 0.1 mL.min-1.g-1; P = .008) and renal cortical vascular resistance increases (basal versus handgrip, 17 +/- 1 versus 26 +/- 2 U; P = .01) in response to static handgrip exercise; (2) central command and/or the mechanoreflex contributes importantly to the early decrease in renal blood flow (basal versus handgrip, 4.2 +/- 0.2 versus 3.5 +/- 0.3 mL.min-1.g-1; P = .04) and to the increase in renal cortical vascular resistance (basal versus handgrip, 20 +/- 1 versus 25 +/- 2 U; P = .04); (3) the muscle metaboreflex contributes to further decreases in renal blood flow (basal versus posthandgrip circulatory arrest, 4.3 +/- 0.1 versus 3.5 +/- 0.2 mL.min-1.g-1; P = .002) and increases in renal cortical vascular resistance (basal versus handgrip, 18 +/- 1 versus 25 +/- 3 U; P = .002); and (4) exogenous adenosine activates the muscle metaboreflex producing reflex renal vasoconstriction and decreased renal blood flow, which may implicate endogenous adenosine generated during ischemic exercise as a potential activator of the muscle metaboreflex during ischemic handgrip exercise.	Adenosine	1106-1115	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
9024004-2	1997	It rapidly converted maltose to panose (Glc alpha-->6 Glc alpha l-->4 Glc) with a Vmax value of 5.8 mmol l-1 min-1 at 50 degrees C in 0.05 mol l-1 sodium acetate buffer (pH 4.4).	Maltose	21-28	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
9038595-13	1997	Predicted maximum oxygen uptake increased in walkers by 2.1 (0.9) ml min-1 kg-1 (P = 0.02).	Oxygen	18-24	CD59 molecule (CD59 blood group)	Homo sapiens	69-79
9324166-4	1997	In the whole series, the 95% confidence interval of GEC predicted by 45-min galactose was as large as +/- 1.55mg x kg(-1) x min(-1) as absolute value, corresponding to a range from -41 to +47% of measured GEC.	Galactose	76-85	CD59 molecule (CD59 blood group)	Homo sapiens	124-130
9049516-7	1997	The increase in coronary blood flow in response to acetylcholine, at doses of 1, 3, 10, and 30 micrograms.min-1, was also significantly lower in the syndrome X group (12 +/- 13 (P < 0.05), 41 +/- 33, 57 +/- 68, and 124 +/- 87% (P < 0.001)) as compared to the control group (76 +/- 49, 214 +/- 116, 355 +/- 115, and 361 +/- 74%).	Acetylcholine	51-64	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
9049519-8	1997	Cardiac free carnitine balance changed from uptake (255 +/- 107 pmol.min-1, mean +/- SEM) to release, (-150 +/- 66 pmol.min-1) at 30 min after pacing in the group with lactate production.	Carnitine	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
9049519-8	1997	Cardiac free carnitine balance changed from uptake (255 +/- 107 pmol.min-1, mean +/- SEM) to release, (-150 +/- 66 pmol.min-1) at 30 min after pacing in the group with lactate production.	Carnitine	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
9049519-8	1997	Cardiac free carnitine balance changed from uptake (255 +/- 107 pmol.min-1, mean +/- SEM) to release, (-150 +/- 66 pmol.min-1) at 30 min after pacing in the group with lactate production.	Lactic Acid	168-175	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
9049519-8	1997	Cardiac free carnitine balance changed from uptake (255 +/- 107 pmol.min-1, mean +/- SEM) to release, (-150 +/- 66 pmol.min-1) at 30 min after pacing in the group with lactate production.	Lactic Acid	168-175	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
9049522-8	1997	Following dipyridamole, myocardial blood flow was 1.64 (0.44) ml.min-1.g.-1 in hypertrophic cardiomyopathy patients vs 3.50 (0.95) ml.min-1.g-1 for the hypertrophic cardiomyopathy matched control group, P = 0.0001.	Dipyridamole	10-22	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
9049522-9	1997	For the left ventricular hypertrophy patients, post-dipyridamole myocardial blood flow was 2.27 (0.60) ml.min-1.g-1 vs 2.94 (1.29) ml.min-1.g-1 for the left ventricular hypertrophy controls, P = 0.06.	Dipyridamole	52-64	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
9112062-16	1997	With regard to heart rate (HR) there were distinct differences between the two formulations: Following administration of 5, 10 and 20 mg nisoldipine solution, there were dose-dependent increases in HR by a maximum of 4, 12 and 16 beats.min-1, respectively, whereas the HR profile for the NCC was similar to that seen under placebo treatment.	Nisoldipine	137-148	CD59 molecule (CD59 blood group)	Homo sapiens	236-241
9143862-7	1997	RESULTS: Celiprolol increased muscle blood flow by 74%, from 3.4 to 5.9 ml.min-1.100 g-1 muscle in the basal state.	Celiprolol	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
9143862-9	1997	Celiprolol significantly decreased diastolic blood pressure from 82 to 73 mmHg and increased heart rate from 61 to 68 beats.min-1, which suggests sympathetic activation.	Celiprolol	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
9143862-10	1997	Insulin-stimulated glucose uptake was reduced by 46% in the whole body, from 39 to 21 mumol.kg-1.min-1 and by 59% in the femoral muscles, from 99 to 41 mumol.kg-1.min-1, with celiprolol as compared to saline.	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
9143862-10	1997	Insulin-stimulated glucose uptake was reduced by 46% in the whole body, from 39 to 21 mumol.kg-1.min-1 and by 59% in the femoral muscles, from 99 to 41 mumol.kg-1.min-1, with celiprolol as compared to saline.	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
9013128-1	1997	Hydrogen peroxide induces rapid oxidation of metmyoglobin with an apparent second order rate constant, k1 = 3.4 x 10(4) M-1 min-1.	Hydrogen Peroxide	0-17	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
27405407-4	1997	The abnormal sensitivity is explained by a lack of complement regulatory membrane proteins such as decay-accelerating factor (DAF, CD55) and membrane inhibitor of reactive lysis (MIRL, CD59), which are covalently linked to the erythrocyte membrane through a glycosylphosphatidylinositol (GPI) anchor.	Glycosylphosphatidylinositols	258-286	CD59 molecule (CD59 blood group)	Homo sapiens	141-177
27405407-4	1997	The abnormal sensitivity is explained by a lack of complement regulatory membrane proteins such as decay-accelerating factor (DAF, CD55) and membrane inhibitor of reactive lysis (MIRL, CD59), which are covalently linked to the erythrocyte membrane through a glycosylphosphatidylinositol (GPI) anchor.	Glycosylphosphatidylinositols	258-286	CD59 molecule (CD59 blood group)	Homo sapiens	179-183
27405407-4	1997	The abnormal sensitivity is explained by a lack of complement regulatory membrane proteins such as decay-accelerating factor (DAF, CD55) and membrane inhibitor of reactive lysis (MIRL, CD59), which are covalently linked to the erythrocyte membrane through a glycosylphosphatidylinositol (GPI) anchor.	Glycosylphosphatidylinositols	258-286	CD59 molecule (CD59 blood group)	Homo sapiens	185-189
27405407-4	1997	The abnormal sensitivity is explained by a lack of complement regulatory membrane proteins such as decay-accelerating factor (DAF, CD55) and membrane inhibitor of reactive lysis (MIRL, CD59), which are covalently linked to the erythrocyte membrane through a glycosylphosphatidylinositol (GPI) anchor.	Glycosylphosphatidylinositols	288-291	CD59 molecule (CD59 blood group)	Homo sapiens	141-177
27405407-4	1997	The abnormal sensitivity is explained by a lack of complement regulatory membrane proteins such as decay-accelerating factor (DAF, CD55) and membrane inhibitor of reactive lysis (MIRL, CD59), which are covalently linked to the erythrocyte membrane through a glycosylphosphatidylinositol (GPI) anchor.	Glycosylphosphatidylinositols	288-291	CD59 molecule (CD59 blood group)	Homo sapiens	179-183
27405407-4	1997	The abnormal sensitivity is explained by a lack of complement regulatory membrane proteins such as decay-accelerating factor (DAF, CD55) and membrane inhibitor of reactive lysis (MIRL, CD59), which are covalently linked to the erythrocyte membrane through a glycosylphosphatidylinositol (GPI) anchor.	Glycosylphosphatidylinositols	288-291	CD59 molecule (CD59 blood group)	Homo sapiens	185-189
9038722-1	1997	CD59-antigen (protectin) is a widely distributed glycolipid-anchored inhibitor of complement lysis.	Glycolipids	49-59	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
9038722-4	1997	By using primarily soluble CD59 isolated from urine (CD59U) potentially non-specific binding interactions of the phospholipid portion of the membrane forms of CD59 could be avoided.	cd59u	53-58	CD59 molecule (CD59 blood group)	Homo sapiens	27-31
9038722-4	1997	By using primarily soluble CD59 isolated from urine (CD59U) potentially non-specific binding interactions of the phospholipid portion of the membrane forms of CD59 could be avoided.	Phospholipids	113-125	CD59 molecule (CD59 blood group)	Homo sapiens	27-31
9038722-4	1997	By using primarily soluble CD59 isolated from urine (CD59U) potentially non-specific binding interactions of the phospholipid portion of the membrane forms of CD59 could be avoided.	Phospholipids	113-125	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
9024004-2	1997	It rapidly converted maltose to panose (Glc alpha-->6 Glc alpha l-->4 Glc) with a Vmax value of 5.8 mmol l-1 min-1 at 50 degrees C in 0.05 mol l-1 sodium acetate buffer (pH 4.4).	panose	32-38	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
9024004-2	1997	It rapidly converted maltose to panose (Glc alpha-->6 Glc alpha l-->4 Glc) with a Vmax value of 5.8 mmol l-1 min-1 at 50 degrees C in 0.05 mol l-1 sodium acetate buffer (pH 4.4).	Sodium Acetate	153-167	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
9365972-2	1997	In patients receiving atropine heart rate increased 8.8 beats.min-1 (8.7%) and 16.2 beats.min-1 (16.0%) after 3 and 5 min respectively.	Atropine	22-30	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
9365972-2	1997	In patients receiving atropine heart rate increased 8.8 beats.min-1 (8.7%) and 16.2 beats.min-1 (16.0%) after 3 and 5 min respectively.	Atropine	22-30	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
9038437-2	1996	The average consumption (SD) of isoflurane in 37 patients anaesthetised using the A mode of the Carden system with a mean fresh gas flow of 2.61 min-1 was 11.1 (4.2) g.h-1, while that in 40 patients anaesthetised using the circle absorber mode with a mean fresh gas flow of 1.21 min-1 was 4.7 (1.0) g.h-1.	Isoflurane	32-42	CD59 molecule (CD59 blood group)	Homo sapiens	279-284
8990356-12	1996	The mean serum creatinine level was 1.2+/-0.8 mg/dl, and the calculated creatinine clearance was 82+/-26 ml/min/1.73 m2.	Creatinine	72-82	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
9020998-3	1996	A total of 30 physically healthy volunteers, 15 patients with DSM-III-R major depression and an age- and sex-matched control group received a standardized challenge of hydrocortisone (5 micrograms kg-1 min-1) or placebo over a period of 1 h. ACTH1-39 responses to hydrocortisone challenge did not differ significantly between healthy volunteers and patients with major depression.	Hydrocortisone	168-182	CD59 molecule (CD59 blood group)	Homo sapiens	202-207
9038447-3	1996	The generator was found to supply a mean (SD) flow of oxygen of 3.6 (0.01) l.min-1 for 12.5 (range 12.4-12.6)min.	Oxygen	54-60	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
9038447-4	1996	The mean (SD) total volume of oxygen produced was 47(0.17) l. The supplied oxygen mask was a variable performance type with the problems and limitations inherent in this design; an oxygen flow of 8 l.min-1 is required to provide 40% oxygen and most of the oxygen is wasted and not available to the patient.	Oxygen	30-36	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
9038447-4	1996	The mean (SD) total volume of oxygen produced was 47(0.17) l. The supplied oxygen mask was a variable performance type with the problems and limitations inherent in this design; an oxygen flow of 8 l.min-1 is required to provide 40% oxygen and most of the oxygen is wasted and not available to the patient.	Oxygen	75-81	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
9038447-4	1996	The mean (SD) total volume of oxygen produced was 47(0.17) l. The supplied oxygen mask was a variable performance type with the problems and limitations inherent in this design; an oxygen flow of 8 l.min-1 is required to provide 40% oxygen and most of the oxygen is wasted and not available to the patient.	Oxygen	75-81	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
9038447-4	1996	The mean (SD) total volume of oxygen produced was 47(0.17) l. The supplied oxygen mask was a variable performance type with the problems and limitations inherent in this design; an oxygen flow of 8 l.min-1 is required to provide 40% oxygen and most of the oxygen is wasted and not available to the patient.	Oxygen	75-81	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
9038447-4	1996	The mean (SD) total volume of oxygen produced was 47(0.17) l. The supplied oxygen mask was a variable performance type with the problems and limitations inherent in this design; an oxygen flow of 8 l.min-1 is required to provide 40% oxygen and most of the oxygen is wasted and not available to the patient.	Oxygen	75-81	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
9014629-2	1996	In an uncontrolled, open study, we administered sequentially different doses of dopamine (0, 2, 4, 8 and 0 microgram kg-1 min-1) during a 1-h period each.	Dopamine	80-88	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
8982497-7	1996	NKA and SP (0.14-3.78 nmol min-1 kg-1, infused intra-aortically) inhibited the gastric mucosal hyperaemic response to acid back-diffusion in a dose-dependent manner, an effect that was accompanied by aggravation of ethanol/acid-induced macroscopic haemorrhagic lesions.	Ethanol	215-222	CD59 molecule (CD59 blood group)	Homo sapiens	27-37
8982497-9	1996	The inhibitory effect of NKA (1.26 nmol min-1 kg-1) on the acid-induced gastric mucosal vasodilatation was prevented by the tachykinin NK2 receptor antagonists, MEN 10,627 (200 nmol kg-1) but left unaltered by the NK1 receptor antagonist, SR 140,333 (300 nmol kg-1) and the mast-cell stabilizer, ketotifen (4.6 mumol kg-1).	Ketotifen	296-305	CD59 molecule (CD59 blood group)	Homo sapiens	40-50
8989056-3	1996	Mean preoperative DM was reduced in patients with CTEPH (28 mL min-1 mm Hg-1 vs 43 mL min-1 mm Hg-1 in control subjects; p < 0.001) and dropped significantly following PTE (21 mL min-1 mm Hg-1; p < 0.001).	cteph	50-55	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
8989056-3	1996	Mean preoperative DM was reduced in patients with CTEPH (28 mL min-1 mm Hg-1 vs 43 mL min-1 mm Hg-1 in control subjects; p < 0.001) and dropped significantly following PTE (21 mL min-1 mm Hg-1; p < 0.001).	cteph	50-55	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
8989056-3	1996	Mean preoperative DM was reduced in patients with CTEPH (28 mL min-1 mm Hg-1 vs 43 mL min-1 mm Hg-1 in control subjects; p < 0.001) and dropped significantly following PTE (21 mL min-1 mm Hg-1; p < 0.001).	cteph	50-55	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
8960434-6	1996	Dobutamine was progressively increased (5-40 micrograms.kg-1.min-1) and atropine was injected in 30 patients.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
8960434-8	1996	RESULTS: The mean peak dobutamine dose was 32 +/- 11 micrograms.kg-1.min-1.	Dobutamine	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
8969127-2	1996	Before basic training the mean maximal oxygen uptake predicted from cycle ergometry (pred VO2max) for Adult Artillery Recruits was 56.1 ml (kg min)-1.	Oxygen	39-45	CD59 molecule (CD59 blood group)	Homo sapiens	143-149
8977994-11	1996	Dobutamine infusion increased heart rate (to about 190 x min-1 and CI by 30% in normovolemia and hypovolemia, while ITBV remained basically unchanged.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
10168560-3	1996	Blood flow was reduced to 30-50 mL min-1 depending on the children"s size and weight to prevent citrate reactions.	Citric Acid	96-103	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
8955462-6	1996	The hepatic glucose production rate averaged 25.0 +/- 3.5 mumol.kg-1 min-1 (4.5 +/- 0.6 mg.kg-1.min-1) and the endogenous plasma appearance rate of glycerol 8.7 +/- 1.2 mumol.kg-1.min.	Glucose	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
8955462-6	1996	The hepatic glucose production rate averaged 25.0 +/- 3.5 mumol.kg-1 min-1 (4.5 +/- 0.6 mg.kg-1.min-1) and the endogenous plasma appearance rate of glycerol 8.7 +/- 1.2 mumol.kg-1.min.	Glucose	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
8895265-6	1996	Regional myocardial lactate uptake (RMLU) and extraction (RMLE) increased significantly (P < 0.05) at 50 ng.kg-1.min-1 (10.2 +/- 3.8 mumol/min and 8.2% +/- 3.0%, respectively) as compared to control (-1.1 +/- 3.0 mumol/min and -1.3% +/- 3.3%, respectively).	Lactic Acid	20-27	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
8895288-7	1996	The infusion rates for a 95% +/- 4% neuromuscular block were 1.5 +/- 0.4 micrograms.kg-1.min-1 for cisatracurium and 6.6 +/- 1.7 micrograms.kg-1.min-1 for atracurium, 3.3 times those of cisatracurium when referenced to the active cations.	cisatracurium	99-112	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
8929278-2	1996	A four-step purification procedure comprising Q-Sepharose, hydroxyapatite, and phenyl-Superose chromatography and ultrafiltration resulted in a 13.7-fold purified enzyme with a final specific activity of 2.0 mmol min-1 (mg protein)-1.	phenyl-superose	79-94	CD59 molecule (CD59 blood group)	Homo sapiens	213-233
8951189-4	1996	In the single dose studies, the half-life of (-)-sotalol (7.2-8.5 h) was significantly (P < 0.01) shorter than that of (+)-sotalol (9.1-11.4 h) while the renal clearance of (-)-sotalol (110.6-126.4 ml min-1) was significantly (P < 0.01) faster than that of (+)-sotalol (102.2-110.1 ml min-1).	Sotalol	45-56	CD59 molecule (CD59 blood group)	Homo sapiens	204-209
8951189-4	1996	In the single dose studies, the half-life of (-)-sotalol (7.2-8.5 h) was significantly (P < 0.01) shorter than that of (+)-sotalol (9.1-11.4 h) while the renal clearance of (-)-sotalol (110.6-126.4 ml min-1) was significantly (P < 0.01) faster than that of (+)-sotalol (102.2-110.1 ml min-1).	Sotalol	45-56	CD59 molecule (CD59 blood group)	Homo sapiens	291-296
8898700-8	1996	The mean difference CBFKS-CBFTH is -0.9 +/- 3.6 ml min-1 100 g-1.	cbfks	20-25	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
9065247-15	1996	RESULTS: The model-dependent pharmacokinetic parameters of eltanolone were characterized by a high total clearance (1.75 +/- 0.22 l min-1), small volumes of distribution (Vc = 7.7 +/- 3.4 l; Vdss = 92 +/- 22 l and relatively short half-lives (t1/2 alpha = 1.5 +/- 0.6 min; t1/2 beta = 27 +/- 5 min; t1/2 gamma = 184 +/- 32 min).	Pregnanolone	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
9065257-7	1996	The total clearance of Ro 48-6791 was found to be 1410 +/- 380 vs. 399 +/- 91 ml min-1 for midazolam (mean +/- SD; P < 0.005) and the central volume of distribution to be 20.5 +/- 7.1 vs. 7.9 +/- 3.0 l, respectively (P < 0.005).	Midazolam	91-100	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
8903329-8	1996	Whole-body glucose uptake was 37+/-4 micromol x min(-1) x kg(-1) in controls and 14+/-2 mciromol x min(-1) x kg(-1) in patients (P = 0.001).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	48-54
8898700-8	1996	The mean difference CBFKS-CBFTH is -0.9 +/- 3.6 ml min-1 100 g-1.	cbfth	26-31	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
8831723-5	1996	Presence of CuSO4 (2 microM) did not significantly affect the potency of 2,2-diethyl-1-nitroso-oxyhydrazine (DEA/NO) but did markedly decrease maximal cyclase activity from 3.71 +/- 0.2 mumol cGMP x mg-1 x min-1 to 1.75 +/- 0.2 mumol cGMP x mg-1 x min-1.	Copper Sulfate	12-17	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
8931644-1	1996	The rate of protein synthesis was assessed in muscle, lymphocytes, and albumin in healthy volunteers administered an infusion of 6.0 micrograms cortisol +3.0 ng glucagon +0.5 nmol epinephrine min-1.kg-1.	Epinephrine	180-191	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
8824203-6	1996	The most catalytically efficient substrate identified was bis-(p-nitrophenyl) phosphate with a Km of 0.9 mM and a kcat of 6.2 x 10(2) min-1, suggesting that the enzyme may also function in vivo as a phosphodiesterase.	bis(4-nitrophenyl)phosphate	58-87	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
8831723-5	1996	Presence of CuSO4 (2 microM) did not significantly affect the potency of 2,2-diethyl-1-nitroso-oxyhydrazine (DEA/NO) but did markedly decrease maximal cyclase activity from 3.71 +/- 0.2 mumol cGMP x mg-1 x min-1 to 1.75 +/- 0.2 mumol cGMP x mg-1 x min-1.	Copper Sulfate	12-17	CD59 molecule (CD59 blood group)	Homo sapiens	248-253
8897921-4	1996	After dipyridamole, myocardial blood flow during alpha 1-blockade was significantly higher (3.50 +/- 0.75 vs. 2.58 +/- 0.54 ml.min-1.g-1; P < 0.01) and coronary resistance lower (25.30 +/- 7.37 vs. 33.89 +/- 7.04 mmHg.min.ml-1.g-1; P < 0.01) compared with control.	Dipyridamole	6-18	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
8897869-6	1996	This was verified using standard biochemical analysis; from the rate (mumol.min-1.g dry wt-1) of propionate uptake (4.0 +/- 0.7), the estimated oxygen consumption (24.8 +/- 5) matched that experimentally determined (24.4 +/- 3).	Propionates	97-107	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
8873540-7	1996	RESULTS: Alfentanil decreased the slope of the carbon dioxide response curve from 2.14 +/- 0.40 to 1.43 +/- 0.19 l.min-1.mmHg-1 (x +/- SE, P < 0.05), and decreased the minute ventilation at P(ET)CO2 = 50 mmHg (VE50) from 19.7 +/- 1.2 to 14.8 +/- 0.9l.min-1 (P < 0.05).	Carbon Dioxide	47-61	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
8873540-7	1996	RESULTS: Alfentanil decreased the slope of the carbon dioxide response curve from 2.14 +/- 0.40 to 1.43 +/- 0.19 l.min-1.mmHg-1 (x +/- SE, P < 0.05), and decreased the minute ventilation at P(ET)CO2 = 50 mmHg (VE50) from 19.7 +/- 1.2 to 14.8 +/- 0.9l.min-1 (P < 0.05).	Alfentanil	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
8873540-7	1996	RESULTS: Alfentanil decreased the slope of the carbon dioxide response curve from 2.14 +/- 0.40 to 1.43 +/- 0.19 l.min-1.mmHg-1 (x +/- SE, P < 0.05), and decreased the minute ventilation at P(ET)CO2 = 50 mmHg (VE50) from 19.7 +/- 1.2 to 14.8 +/- 0.9l.min-1 (P < 0.05).	Alfentanil	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	254-259
8984860-3	1996	Using a fresh gas flow of 1 l.min-1, the ratio of inspired desflurane concentration to desflurane vaporizer setting was found to be approximately 0.75 after 9 min of anaesthesia and at 2 l.min-1 fresh gas flow the ratio was approximately 0.9 after 2 min of anaesthesia.	Desflurane	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
8984860-3	1996	Using a fresh gas flow of 1 l.min-1, the ratio of inspired desflurane concentration to desflurane vaporizer setting was found to be approximately 0.75 after 9 min of anaesthesia and at 2 l.min-1 fresh gas flow the ratio was approximately 0.9 after 2 min of anaesthesia.	Desflurane	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	189-194
8984860-3	1996	Using a fresh gas flow of 1 l.min-1, the ratio of inspired desflurane concentration to desflurane vaporizer setting was found to be approximately 0.75 after 9 min of anaesthesia and at 2 l.min-1 fresh gas flow the ratio was approximately 0.9 after 2 min of anaesthesia.	Desflurane	87-97	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
8984860-3	1996	Using a fresh gas flow of 1 l.min-1, the ratio of inspired desflurane concentration to desflurane vaporizer setting was found to be approximately 0.75 after 9 min of anaesthesia and at 2 l.min-1 fresh gas flow the ratio was approximately 0.9 after 2 min of anaesthesia.	Desflurane	87-97	CD59 molecule (CD59 blood group)	Homo sapiens	189-194
8894174-11	1996	Breakdown of GSNO showed a non-significant acceleration in the presence of cysteine, from 0.56 +/- 0.22 to 1.77 +/- 0.27 nmol min-1 (mean +/- s.e.mean) (P = 0.064, n = 4), and its ability to inhibit platelet aggregation was not enhanced by cysteine.	S-Nitrosoglutathione	13-17	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
8894174-11	1996	Breakdown of GSNO showed a non-significant acceleration in the presence of cysteine, from 0.56 +/- 0.22 to 1.77 +/- 0.27 nmol min-1 (mean +/- s.e.mean) (P = 0.064, n = 4), and its ability to inhibit platelet aggregation was not enhanced by cysteine.	Cysteine	75-83	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
8983867-2	1996	Adrenaline was infused at a rate of 25 ng min-1 kg-1 into seven healthy volunteers and its effects on adipose tissue were studied by microdialysis.	Epinephrine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	42-52
8898942-3	1996	On the other hand, there are indications that signaling through T cell surface molecules anchored via glycosylphosphatidylinositol (GPI), such as Thy-1, Ly-6 or CD59, is dependent on the TCR.	Glycosylphosphatidylinositols	102-130	CD59 molecule (CD59 blood group)	Homo sapiens	161-165
8911859-4	1996	Eight patients with ulcerative colitis expressed calcium-independent citrulline activity (9.96 +/- 2.34 pmol citrulline mg-1 protein min-1) and showed immunoreactivity to the iNOS antibody within the inflammatory infiltrate of the lamina propria, and also within the cytoplasm of the epithelial cells lining the colon.	Calcium	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
8911859-4	1996	Eight patients with ulcerative colitis expressed calcium-independent citrulline activity (9.96 +/- 2.34 pmol citrulline mg-1 protein min-1) and showed immunoreactivity to the iNOS antibody within the inflammatory infiltrate of the lamina propria, and also within the cytoplasm of the epithelial cells lining the colon.	Citrulline	69-79	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
8873540-7	1996	RESULTS: Alfentanil decreased the slope of the carbon dioxide response curve from 2.14 +/- 0.40 to 1.43 +/- 0.19 l.min-1.mmHg-1 (x +/- SE, P < 0.05), and decreased the minute ventilation at P(ET)CO2 = 50 mmHg (VE50) from 19.7 +/- 1.2 to 14.8 +/- 0.9l.min-1 (P < 0.05).	Carbon Dioxide	47-61	CD59 molecule (CD59 blood group)	Homo sapiens	254-259
8873540-7	1996	RESULTS: Alfentanil decreased the slope of the carbon dioxide response curve from 2.14 +/- 0.40 to 1.43 +/- 0.19 l.min-1.mmHg-1 (x +/- SE, P < 0.05), and decreased the minute ventilation at P(ET)CO2 = 50 mmHg (VE50) from 19.7 +/- 1.2 to 14.8 +/- 0.9l.min-1 (P < 0.05).	Carbon Dioxide	198-201	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
8873540-8	1996	Midazolam further reduced these variables to 0.87 +/- 0.17 l.min-1.mmHg-1 (P < 0.05) and 11.7 +/- 0.8 l.min-1 (P < 0.05), respectively.	Midazolam	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
8873540-8	1996	Midazolam further reduced these variables to 0.87 +/- 0.17 l.min-1.mmHg-1 (P < 0.05) and 11.7 +/- 0.8 l.min-1 (P < 0.05), respectively.	Midazolam	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
8873540-9	1996	With addition of flumazenil, slope and VE50 increased to 1.47 +/- 0.37 l.min-1.mmHg-1 (P < 0.05) and 16.4 +/- 2.0l.min-1 (P < 0.05); after placebo, the respective values of 1.02 +/- 0.19 l.min-1.mmHg-1 and 12.5 +/- 1.2 l.min-1 did not differe significantly from their values during combined alfentanil and midazolam administration.	Flumazenil	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
8873540-9	1996	With addition of flumazenil, slope and VE50 increased to 1.47 +/- 0.37 l.min-1.mmHg-1 (P < 0.05) and 16.4 +/- 2.0l.min-1 (P < 0.05); after placebo, the respective values of 1.02 +/- 0.19 l.min-1.mmHg-1 and 12.5 +/- 1.2 l.min-1 did not differe significantly from their values during combined alfentanil and midazolam administration.	Flumazenil	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
8873540-9	1996	With addition of flumazenil, slope and VE50 increased to 1.47 +/- 0.37 l.min-1.mmHg-1 (P < 0.05) and 16.4 +/- 2.0l.min-1 (P < 0.05); after placebo, the respective values of 1.02 +/- 0.19 l.min-1.mmHg-1 and 12.5 +/- 1.2 l.min-1 did not differe significantly from their values during combined alfentanil and midazolam administration.	Flumazenil	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
8873540-9	1996	With addition of flumazenil, slope and VE50 increased to 1.47 +/- 0.37 l.min-1.mmHg-1 (P < 0.05) and 16.4 +/- 2.0l.min-1 (P < 0.05); after placebo, the respective values of 1.02 +/- 0.19 l.min-1.mmHg-1 and 12.5 +/- 1.2 l.min-1 did not differe significantly from their values during combined alfentanil and midazolam administration.	Flumazenil	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
8912225-4	1996	Five incremental doses of noradrenaline acid tartrate (0.33-33.33 ng min-1) were infused twice in each subject: first with 5-min washout (5% dextrose saline) periods in between ("noncumulative dose-response curve"), then without interspersed washout periods ("cumulative dose-response curve").	Norepinephrine	26-53	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
8876745-3	1996	Close-arterial infusion of enalaprilat (0.05-0.20 mg kg muscle tissue min-1) elicited a moderate dilator response in all three consecutive sections of the muscle vascular bed, an increase in capillary pressure and transcapillary fluid filtration.	Enalaprilat	27-38	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
8798614-1	1996	CD59 is a glycosylphosphatidylinositol-anchored membrane glycoprotein that serves as the principle cellular inhibitor of the C5b-9 membrane attack complex (MAC) of human complement.	Glycosylphosphatidylinositols	10-38	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
8798614-2	1996	Approximately 50% of the total apparent mass of CD59 is attributable to glycosylation of a single Asn (Asn18).	Asparagine	98-101	CD59 molecule (CD59 blood group)	Homo sapiens	48-52
8798614-5	1996	In this study, we specifically examined how deletion or transposition of the site of N-linked glycosylation in the CD59 polypeptide affects its MAC inhibitory function.	Nitrogen	85-86	CD59 molecule (CD59 blood group)	Homo sapiens	115-119
8798614-7	1996	Furthermore, we show that CD59 retains normal MAC regulatory function when mutated to eliminate all potential sites for N-linked glycosylation.	Nitrogen	120-121	CD59 molecule (CD59 blood group)	Homo sapiens	26-30
8908223-4	1996	METHODS: Twenty-one ASA 1 female patients scheduled for gynaecologic surgery received propofol for induction at 133 mg.min-1.	Propofol	86-94	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
8876745-4	1996	This dilation could be abolished by the selective bradykinin B2-receptor antagonist Hoe 140 (2 mg kg-1 min-1, i.a.	4-hydroxy-2-octenal	84-87	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
8876745-8	1996	The specific angiotensin AT1-receptor antagonist losartan (2 mg kg-1 min-1, i.a.)	Losartan	49-57	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
8949820-2	1996	Sevoflurane (approximately 1.0 MAC) was delivered in 50-66% nitrous oxide in oxygen via a circle system, with a fresh gas flow of 6 litre min-1.	Sevoflurane	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
8853410-6	1996	At the end of each diet, urodilatin was infused for 2 h at 20 ng.kg body wt-1.min-1.	Ularitide	25-35	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
8853079-9	1996	RESULTS: Prebypass propofol at 243 +/- 57 micrograms.kg-1.min-1 decreased vascular resistance from 34 +/- 8 to 27 +/- 8 units without changing heart rate, arterial or filling pressures, cardiac index, stroke volume, or ejection fraction.	Propofol	19-27	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
8877025-12	1996	Apparent oral clearances of R- and S-propranolol were higher (P < 0.05) in blacks than whites (R-propranolol: 5036 +/- 4175 ml min-1 vs 2854 +/- 879 ml min-1; S-propranolol 3255 +/- 1723 ml min-1 vs 2125 +/- 510 ml min-1; blacks vs whites).	r- and s-propranolol	28-48	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
8877025-12	1996	Apparent oral clearances of R- and S-propranolol were higher (P < 0.05) in blacks than whites (R-propranolol: 5036 +/- 4175 ml min-1 vs 2854 +/- 879 ml min-1; S-propranolol 3255 +/- 1723 ml min-1 vs 2125 +/- 510 ml min-1; blacks vs whites).	r- and s-propranolol	28-48	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
8877025-12	1996	Apparent oral clearances of R- and S-propranolol were higher (P < 0.05) in blacks than whites (R-propranolol: 5036 +/- 4175 ml min-1 vs 2854 +/- 879 ml min-1; S-propranolol 3255 +/- 1723 ml min-1 vs 2125 +/- 510 ml min-1; blacks vs whites).	r- and s-propranolol	28-48	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
8877025-12	1996	Apparent oral clearances of R- and S-propranolol were higher (P < 0.05) in blacks than whites (R-propranolol: 5036 +/- 4175 ml min-1 vs 2854 +/- 879 ml min-1; S-propranolol 3255 +/- 1723 ml min-1 vs 2125 +/- 510 ml min-1; blacks vs whites).	r- and s-propranolol	28-48	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
8889117-7	1996	RESULTS: The average heart rate and oxygen consumption during the match were 146.5 (SD 9.25) beats min-1 and 2.25(0.59) litre min-1 respectively.	Oxygen	36-42	CD59 molecule (CD59 blood group)	Homo sapiens	99-110
8877293-7	1996	dl-1, both n = 12), 2) the new sulphonylurea derivative glimepiride (2.5 micrograms.min-1.	glimepiride	56-67	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
8889439-7	1996	In 10 out of these 15 individuals, the forearm glucose uptake was further increased in a second, separate, repeat experiment with concomitant intra-arterial infusion of glucose 5% (0.2 mL dL-1 min-1), resulting in forearm venous glucose concentrations of approximately 15 mmol L-1.	Glucose	169-176	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
8889439-7	1996	In 10 out of these 15 individuals, the forearm glucose uptake was further increased in a second, separate, repeat experiment with concomitant intra-arterial infusion of glucose 5% (0.2 mL dL-1 min-1), resulting in forearm venous glucose concentrations of approximately 15 mmol L-1.	Glucose	169-176	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
8925507-4	1996	Loading and clean-up of the samples and regeneration of the detergent trapping column were performed at 50 microl min(-1), resulting in sample clean-up times of only 30 s. SDS-containing tryptic digested protein samples were directly applied to the micro-precolumns without any previous sample pretreatment.	Sodium Dodecyl Sulfate	172-175	CD59 molecule (CD59 blood group)	Homo sapiens	114-120
8890564-1	1996	Decay-accelerating factor (DAF) and CD59 are major complement regulators linked to plasma membrane via glycosylphosphatidylinositol anchor and inhibit C3 activation and the formation of membrane attack complex, respectively.	Glycosylphosphatidylinositols	103-131	CD59 molecule (CD59 blood group)	Homo sapiens	36-40
8752313-3	1996	The rates of formation of gold particles from 1 mM Au(III) ions in pure water were 3 microM min-1 under argon atmosphere and approximately zero under air, and in solutions containing additive the rates were 9-133 microM min-1 under argon and 8-40 microM min-1 under air.	au(iii)	51-58	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
8752313-3	1996	The rates of formation of gold particles from 1 mM Au(III) ions in pure water were 3 microM min-1 under argon atmosphere and approximately zero under air, and in solutions containing additive the rates were 9-133 microM min-1 under argon and 8-40 microM min-1 under air.	Argon	232-237	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
8752313-3	1996	The rates of formation of gold particles from 1 mM Au(III) ions in pure water were 3 microM min-1 under argon atmosphere and approximately zero under air, and in solutions containing additive the rates were 9-133 microM min-1 under argon and 8-40 microM min-1 under air.	Argon	232-237	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
8752313-5	1996	The rates of formation of both hydrogen atoms and hydroxyl radicals were estimated to be equal to 25 microM min-1 in the sonolysis of pure water under argon.	Hydrogen	31-39	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
8752313-5	1996	The rates of formation of both hydrogen atoms and hydroxyl radicals were estimated to be equal to 25 microM min-1 in the sonolysis of pure water under argon.	Hydroxyl Radical	50-67	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
8752313-5	1996	The rates of formation of both hydrogen atoms and hydroxyl radicals were estimated to be equal to 25 microM min-1 in the sonolysis of pure water under argon.	Water	139-144	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
8752313-5	1996	The rates of formation of both hydrogen atoms and hydroxyl radicals were estimated to be equal to 25 microM min-1 in the sonolysis of pure water under argon.	Argon	151-156	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
8780523-3	1996	Evidence for Mn2+ as an electrophilic catalyst was supported by the observation that the nonenzymatic transfer of L-fucose from GDP-Fuc to the hydroxyl group of water in the presence of 10 mM MnCl2 at 20 degrees C was accelerated from K(obs)= 3.5 x 10(-6) to 3.8 x 10(-5) min-1.	Manganese(2+)	13-17	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
8780523-3	1996	Evidence for Mn2+ as an electrophilic catalyst was supported by the observation that the nonenzymatic transfer of L-fucose from GDP-Fuc to the hydroxyl group of water in the presence of 10 mM MnCl2 at 20 degrees C was accelerated from K(obs)= 3.5 x 10(-6) to 3.8 x 10(-5) min-1.	Fucose	114-122	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
8780523-3	1996	Evidence for Mn2+ as an electrophilic catalyst was supported by the observation that the nonenzymatic transfer of L-fucose from GDP-Fuc to the hydroxyl group of water in the presence of 10 mM MnCl2 at 20 degrees C was accelerated from K(obs)= 3.5 x 10(-6) to 3.8 x 10(-5) min-1.	Guanosine Diphosphate Fucose	128-135	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
8780523-3	1996	Evidence for Mn2+ as an electrophilic catalyst was supported by the observation that the nonenzymatic transfer of L-fucose from GDP-Fuc to the hydroxyl group of water in the presence of 10 mM MnCl2 at 20 degrees C was accelerated from K(obs)= 3.5 x 10(-6) to 3.8 x 10(-5) min-1.	Water	161-166	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
8780523-3	1996	Evidence for Mn2+ as an electrophilic catalyst was supported by the observation that the nonenzymatic transfer of L-fucose from GDP-Fuc to the hydroxyl group of water in the presence of 10 mM MnCl2 at 20 degrees C was accelerated from K(obs)= 3.5 x 10(-6) to 3.8 x 10(-5) min-1.	manganese chloride	192-197	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
8718880-3	1996	Treatment of the dehalogenase with diethyl pyrocarbonate resulted in complete loss of catalytic activity (Kinact = 0.17 mM-1 min-1 at pH 6.5, 25 degrees C) that was fully regained by subsequent treatment with hydroxylamine.	Diethyl Pyrocarbonate	35-56	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
8718880-3	1996	Treatment of the dehalogenase with diethyl pyrocarbonate resulted in complete loss of catalytic activity (Kinact = 0.17 mM-1 min-1 at pH 6.5, 25 degrees C) that was fully regained by subsequent treatment with hydroxylamine.	Hydroxylamine	209-222	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
8752192-5	1996	Diltiazem induced a systemic vasodilation (cardiac index: 3.4 +/- 1.0 to 4.0 +/- 1.0 L x min(-1) x m(-2), p = 0.003; aortic systolic pressure: 116 +/- 16 to 107 +/- 19 mm Hg, p = 0.007; systemic resistance index: 676 +/- 235 to 532 +/- 193 dynes x s x cm(-5) x m(-2), p = 0.006), not associated with changes in the LV outflow tract gradient.	Diltiazem	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
8759753-2	1996	Membrane inhibitor of reactive lysis (MIRL, CD59) is an 18-kDa glycosylphosphatidylinositol-anchored protein that regulates formation of the membrane attack complex of complement.	Glycosylphosphatidylinositols	63-91	CD59 molecule (CD59 blood group)	Homo sapiens	0-36
8759753-2	1996	Membrane inhibitor of reactive lysis (MIRL, CD59) is an 18-kDa glycosylphosphatidylinositol-anchored protein that regulates formation of the membrane attack complex of complement.	Glycosylphosphatidylinositols	63-91	CD59 molecule (CD59 blood group)	Homo sapiens	38-42
8759753-2	1996	Membrane inhibitor of reactive lysis (MIRL, CD59) is an 18-kDa glycosylphosphatidylinositol-anchored protein that regulates formation of the membrane attack complex of complement.	Glycosylphosphatidylinositols	63-91	CD59 molecule (CD59 blood group)	Homo sapiens	44-48
8862220-7	1996	In contrast, hyperinsulinemia caused a significant decrease in the urinary excretion of uric acid (2.67 +/- 0.12 to 1.86 +/- .14 mumol/min/1.73 m2, P = .0001), sodium (184 +/- 12 to 137 +/- 14 mumol/min/1.73 m2, P = .0001), and potassium (81 +/- 7 to 48 +/- 4 mumol/ min/1.73 m2, P = .0001).	Uric Acid	88-97	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
8862220-7	1996	In contrast, hyperinsulinemia caused a significant decrease in the urinary excretion of uric acid (2.67 +/- 0.12 to 1.86 +/- .14 mumol/min/1.73 m2, P = .0001), sodium (184 +/- 12 to 137 +/- 14 mumol/min/1.73 m2, P = .0001), and potassium (81 +/- 7 to 48 +/- 4 mumol/ min/1.73 m2, P = .0001).	Uric Acid	88-97	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
8862220-7	1996	In contrast, hyperinsulinemia caused a significant decrease in the urinary excretion of uric acid (2.67 +/- 0.12 to 1.86 +/- .14 mumol/min/1.73 m2, P = .0001), sodium (184 +/- 12 to 137 +/- 14 mumol/min/1.73 m2, P = .0001), and potassium (81 +/- 7 to 48 +/- 4 mumol/ min/1.73 m2, P = .0001).	Uric Acid	88-97	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
8694306-14	1996	After tracheal intubation, remifentanil 0.25-4.0 micrograms.kg-1.min-1 effectively controlled intraoperative responses while allowing for rapid emergence from anesthesia.	Remifentanil	27-39	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
8853468-2	1996	Seven highly trained endurance athletes with a mean maximum oxygen uptake of 65 ml.kg-1.min-1, performed two cycle ergometer tests to volitional exhaustion.	Oxygen	60-66	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
8864313-17	1996	Dose reduction of ketoprofen is indicated only for patients with CLCR < 20 ml min-1.	Ketoprofen	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
8864315-9	1996	The difference in the mean (n = 7) total ifosfamide plasma clearance between day 5 and day 1 of Cycle I was an increase of 56.8 ml min-1 (99.8% CIs + 22.6-->+ 91.4).	Ifosfamide	41-51	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8864315-10	1996	The difference in the mean (n = 7) total ifosfamide plasma clearance between day 1 of Cycle II and day 5 was a decrease of 61.9 ml min-1 (99.8% CIs -111.2 -->-12.6).	Ifosfamide	41-51	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8864322-14	1996	Following administration of the ganglion blocking drug pentolinium (5 mg) the incremental systolic blood pressure and heart rate rises following 500 micrograms TRH alone 16.6 +/- 2.8 mmHg and 10.4 + 3.1 beats min-1 respectively.	Pentolinium Tartrate	55-66	CD59 molecule (CD59 blood group)	Homo sapiens	209-214
8864327-5	1996	peak plasma concentrations (Cmax), apparent total clearance (CL/F) and terminal half-life (t1/2) for phenytoin when administered alone were 10.6(1.8) mg 1(-1), 24.3 (7.7) ml min-1 and 25(8) h, respectively.	Phenytoin	101-110	CD59 molecule (CD59 blood group)	Homo sapiens	174-191
8864327-6	1996	When administered together with atovaquone, phenytoin Cmax, CL/F and t1/2,z were 10.9 (2.0) mg 1(-1), 23.8 ml min-1 and 24(6) h, respectively.	Atovaquone	32-42	CD59 molecule (CD59 blood group)	Homo sapiens	110-127
8862953-4	1996	We found that diabetic subjects had a significantly higher GAG urinary excretion rate compared to non-diabetic subjects (12.54 +/- 5.67 vs 8.80 +/- 3.99 micrograms glucuronic acid min-1, p = 0.0001).	Glucuronic Acid	164-179	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
8862953-7	1996	Diabetic subjects excreted more HS GAG than controls both as a rate or as a percentage of total GAG (3.70 +/- 1.94 vs 2.38 +/- 1.48 micrograms glucosamine min-1, p = 0.02; 31.6% +/- 12.5 vs 23.1% +/- 10.4, p = 0.02).	Glucosamine	143-154	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
8866594-10	1996	After 6 microg formoterol, the mean immediate increase in morning PEF was 42 L x min-1 compared to an increase of only 9 L x min-1 after placebo (<0.0001).	Formoterol Fumarate	15-25	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
8866596-9	1996	The mean morning PEF increased from 337 L x min-1 in the salmeterol group and 332 L x min-1 in the theophylline group to 372 and 357 L x min-1, respectively.	Theophylline	99-111	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
8866596-9	1996	The mean morning PEF increased from 337 L x min-1 in the salmeterol group and 332 L x min-1 in the theophylline group to 372 and 357 L x min-1, respectively.	Theophylline	99-111	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
8759358-6	1996	Complement-mediated lysis in the presence of human complement was increased after partial removal of the m-RCA CD55 and CD59 with phosphatidylinositol-specific phospholipase C from the uveal melanoma cell line 92-1.	Phosphatidylinositols	130-150	CD59 molecule (CD59 blood group)	Homo sapiens	120-124
8863271-6	1996	The elimination rate constants were 0.030 +/- 0.002 and 0.07 +/- 0.02 min-1 for cisplatin and the monohydrated complex, respectively.	Cisplatin	80-89	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
8865083-11	1996	The glucose infusion rate (GIR) necessary to maintain euglycaemia during maximal insulin stimulation was lower during PEC compared with CC (15.7%, 81.3 +/- 3.2 vs. 96.4 +/- 8.8 mumol kg-1 min-1, P < 0.05).	Glucose	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
18966601-5	1996	The Leucomethylene Blue formed in the reaction is detected at +0.050 V. At 2.2 ml min(-1) and using a sample loop of 43 mul, the method allows the determination of AA in the range 5.0-90.0 mug ml(-1), with a relative standard deviation of 1.3-4.8%, a detection limit of 1.9 mug ml(-1) and a sampling frequency of 45-50 h(-1).	hydromethylthionine	4-23	CD59 molecule (CD59 blood group)	Homo sapiens	82-88
9035458-1	1996	PURPOSE: To compare patients with heart failure due to Chagas" cardiomyopathy and maximal oxygen consumption greater than 20mL/kg-1/min-1 to normal individuals.	Oxygen	90-96	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
8674327-14	1996	The infusion of norepinephrine decreased renal blood flow from 1241 +/- 208 to 922 +/- 143 mL/min/1.73 m2 (p = .03).	Norepinephrine	16-30	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
8809522-9	1996	(2) In mode 10/60 s, heart rate and systolic blood pressure increased significantly (82 +/- 4 --> 85 +/- 4 beats.min-1; 124 +/- 5 --> 134 +/- 5 mmHg; P < 0.05 each), while in mode 15/60 s catecholamines increased significantly (norepinephrine 0.804 +/- 0.089 --> 1.135 +/- 0.094 nmol.l-1; P < 0.008; epinephrine 0.136 +/- 0.012 --> 0.193 +/- 0.019 nmol.l-1; P < 0.005).	Catecholamines	197-211	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
8809522-9	1996	(2) In mode 10/60 s, heart rate and systolic blood pressure increased significantly (82 +/- 4 --> 85 +/- 4 beats.min-1; 124 +/- 5 --> 134 +/- 5 mmHg; P < 0.05 each), while in mode 15/60 s catecholamines increased significantly (norepinephrine 0.804 +/- 0.089 --> 1.135 +/- 0.094 nmol.l-1; P < 0.008; epinephrine 0.136 +/- 0.012 --> 0.193 +/- 0.019 nmol.l-1; P < 0.005).	Norepinephrine	237-251	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
8809522-9	1996	(2) In mode 10/60 s, heart rate and systolic blood pressure increased significantly (82 +/- 4 --> 85 +/- 4 beats.min-1; 124 +/- 5 --> 134 +/- 5 mmHg; P < 0.05 each), while in mode 15/60 s catecholamines increased significantly (norepinephrine 0.804 +/- 0.089 --> 1.135 +/- 0.094 nmol.l-1; P < 0.008; epinephrine 0.136 +/- 0.012 --> 0.193 +/- 0.019 nmol.l-1; P < 0.005).	Epinephrine	240-251	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
8864417-5	1996	Insulin infusion (7 pmol min-1 kg-1) promoted similar glucose utilization in the hypertensives and normotensives: 24.8 +/- 2.3 vs. 26.0 +/- 3.0 mumol min-1 kg-1 respectively.	Glucose	54-61	CD59 molecule (CD59 blood group)	Homo sapiens	25-35
8698191-5	1996	Total Phe rate of appearance (0.91 +/- 0.13 micromol x kg-1 x min-1) and Leu/Phe disposal ratio (3.53 +/- 0.36) were nearly normalized (fasting controls, 0.68 +/- 0.07 micromol x kg-1 x min-1 and 2.87 +/- 0.14 micromol x kg-1 x min-1, respectively; P>0.05).	Phenylalanine	6-9	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8853277-8	1996	Although both the VE (via an increased f) and CO2 output (VCO2) were significantly greater with LBPP by approximately 30 l min-1 and approximately 500 ml min-1, respectively, end-tidal CO2 partial pressure was decreasing, suggesting an additional ventilatory stimulus.	lbpp	96-100	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8853277-8	1996	Although both the VE (via an increased f) and CO2 output (VCO2) were significantly greater with LBPP by approximately 30 l min-1 and approximately 500 ml min-1, respectively, end-tidal CO2 partial pressure was decreasing, suggesting an additional ventilatory stimulus.	lbpp	96-100	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
8844236-15	1996	The mean NTG infusion rate while MAP was within 5 mmHg of target MAP was 1.14 (0.84 SD) micrograms kg-1 min-1.	Nitroglycerin	9-12	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
8741471-3	1996	MHVBF and Lt. PVBF decreased from preoperative level of 317 +/- 61 ml.min-1, 522 +/- 86 ml.min-1 to 73 +/- 22 ml.min-1, 98 +/- 28 ml.min-1 after inflation with high pneumoperitoneum pressure and they recovered by deflation.	mhvbf	0-5	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
8741471-3	1996	MHVBF and Lt. PVBF decreased from preoperative level of 317 +/- 61 ml.min-1, 522 +/- 86 ml.min-1 to 73 +/- 22 ml.min-1, 98 +/- 28 ml.min-1 after inflation with high pneumoperitoneum pressure and they recovered by deflation.	pvbf	14-18	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
8741471-3	1996	MHVBF and Lt. PVBF decreased from preoperative level of 317 +/- 61 ml.min-1, 522 +/- 86 ml.min-1 to 73 +/- 22 ml.min-1, 98 +/- 28 ml.min-1 after inflation with high pneumoperitoneum pressure and they recovered by deflation.	pvbf	14-18	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
8741471-3	1996	MHVBF and Lt. PVBF decreased from preoperative level of 317 +/- 61 ml.min-1, 522 +/- 86 ml.min-1 to 73 +/- 22 ml.min-1, 98 +/- 28 ml.min-1 after inflation with high pneumoperitoneum pressure and they recovered by deflation.	pvbf	14-18	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
8741471-3	1996	MHVBF and Lt. PVBF decreased from preoperative level of 317 +/- 61 ml.min-1, 522 +/- 86 ml.min-1 to 73 +/- 22 ml.min-1, 98 +/- 28 ml.min-1 after inflation with high pneumoperitoneum pressure and they recovered by deflation.	pvbf	14-18	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
8807596-9	1996	Overexpressed CD59 suppressed production of superoxide, one of the inflammatory mediators induced by sublytic C5b-9 attack.	Superoxides	44-54	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
8692031-9	1996	Mean exogenous CHO oxidation rates during the final hour of exercise were 0.79, 0.63, and 0.73 g x min(-1), respectively.	CAV protocol	15-18	CD59 molecule (CD59 blood group)	Homo sapiens	99-105
8837239-6	1996	The mean plasma clearances of 99mTc-MBP and 51Cr-EDTA in the steady state (4h) were 38.2 and 12.2 ml min-1 (p < 0.01), the peritoneal clearances (0-4 h) were 5.2 and 7.2 ml min-1 (p < 0.01), and the renal clearances (0-4 h) were 2.5 and 2.8 ml min-1 (not significant), respectively.	51cr-edta	44-53	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
8837239-6	1996	The mean plasma clearances of 99mTc-MBP and 51Cr-EDTA in the steady state (4h) were 38.2 and 12.2 ml min-1 (p < 0.01), the peritoneal clearances (0-4 h) were 5.2 and 7.2 ml min-1 (p < 0.01), and the renal clearances (0-4 h) were 2.5 and 2.8 ml min-1 (not significant), respectively.	4h	75-77	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
8837239-7	1996	The bone bisphosphonate clearance (BBC) at steady state was 26.0 ml min-1, a value which was significantly higher than that at infinity (16.5 ml min-1, p < 0.01).	Diphosphonates	9-23	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
8837244-1	1996	Renal function and the urinary excretion rate of albumin (Ualb) at rest and during infusion of dopamine (3 micrograms kg-1 min-1) were investigated in eight normal volunteers at sea level and 48 h after a rapid, passive ascent to an altitude of 4350 m. Oxygen saturation decreased to 81% (77-85) (median with quartiles in parentheses) at high altitude.	Dopamine	95-103	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8837244-5	1996	Infusion of dopamine further increased Ualb to 10.5 micrograms min-1 (5.5-64.8) (p < 0.05) at high altitude, but had no effect on Ualb at sea level.	Dopamine	12-20	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
8837244-5	1996	Infusion of dopamine further increased Ualb to 10.5 micrograms min-1 (5.5-64.8) (p < 0.05) at high altitude, but had no effect on Ualb at sea level.	ualb	39-43	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
9138354-4	1996	RESULTS: The averages found for the pulmonary depuration rate for 99mTc-DTPA were 0.82% +/- 0.19 min-1 for the left lung and of 0.88% +/- 0.23 min-1 for the right lung.	UNII-38IHL67R32	66-76	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
8706691-1	1996	The molybdenum-containing iron-sulfur flavoprotein xanthine dehydrogenase from the anaerobic bacterium Veillonella atypica has been purified approximately 800-fold with a yield of approximately 40% and a specific activity of approximately 70 micromol ferricyanide reduced x min(-1) x mg protein(-1) with xanthine as electron donor, which corresponds to approximately 30 micromol xanthine oxidized x min(-1) x mg protein(-1) with methylene blue as electron acceptor.	Xanthine	51-59	CD59 molecule (CD59 blood group)	Homo sapiens	274-280
8670172-0	1996	Structural composition and functional characterization of soluble CD59: heterogeneity of the oligosaccharide and glycophosphoinositol (GPI) anchor revealed by laser-desorption mass spectrometric analysis.	Oligosaccharides	93-108	CD59 molecule (CD59 blood group)	Homo sapiens	66-70
8670172-0	1996	Structural composition and functional characterization of soluble CD59: heterogeneity of the oligosaccharide and glycophosphoinositol (GPI) anchor revealed by laser-desorption mass spectrometric analysis.	glycophosphoinositol	113-133	CD59 molecule (CD59 blood group)	Homo sapiens	66-70
8670172-0	1996	Structural composition and functional characterization of soluble CD59: heterogeneity of the oligosaccharide and glycophosphoinositol (GPI) anchor revealed by laser-desorption mass spectrometric analysis.	GPI 1046	135-138	CD59 molecule (CD59 blood group)	Homo sapiens	66-70
8670172-1	1996	CD59 (protectin) is a glycophosphoinositol (GPI)-anchored inhibitor of the membrane attack complex of complement found on blood cells, endothelia and epithelial cells.	glycophosphoinositol	22-42	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
8670172-1	1996	CD59 (protectin) is a glycophosphoinositol (GPI)-anchored inhibitor of the membrane attack complex of complement found on blood cells, endothelia and epithelial cells.	GPI 1046	44-47	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
8670172-4	1996	CD59u exhibited an average M(r) of 12444 in MALDI-MS. Mass analysis of the isolated C-terminal peptide (T9) indicated that a GPI-anchor (at Asn-77) without an inositol-associated phospholipid was present in soluble CD59u.	Asparagine	140-143	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
8670172-4	1996	CD59u exhibited an average M(r) of 12444 in MALDI-MS. Mass analysis of the isolated C-terminal peptide (T9) indicated that a GPI-anchor (at Asn-77) without an inositol-associated phospholipid was present in soluble CD59u.	Asparagine	140-143	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
8670172-8	1996	The N-linked carbohydrate side chain of CD59u (at Asn-18) also displayed considerable heterogeneity.	n-linked carbohydrate	4-25	CD59 molecule (CD59 blood group)	Homo sapiens	40-44
8670172-8	1996	The N-linked carbohydrate side chain of CD59u (at Asn-18) also displayed considerable heterogeneity.	Asparagine	50-53	CD59 molecule (CD59 blood group)	Homo sapiens	40-44
8670172-10	1996	Mono Q anion-exchange chromatography resolved urinary CD59 into nine different fractions that bound equally well to the terminal complement SC5b-8 complexes.	Mono Q	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	54-58
8670172-13	1996	These results document the structural heterogeneity of both the GPI anchor and N-linked oligosaccharide of CD59 and demonstrate that the phospholipid tail is needed for the full functional activity of CD59.	GPI 1046	64-67	CD59 molecule (CD59 blood group)	Homo sapiens	201-205
8670172-13	1996	These results document the structural heterogeneity of both the GPI anchor and N-linked oligosaccharide of CD59 and demonstrate that the phospholipid tail is needed for the full functional activity of CD59.	n-linked oligosaccharide	79-103	CD59 molecule (CD59 blood group)	Homo sapiens	107-111
8670172-13	1996	These results document the structural heterogeneity of both the GPI anchor and N-linked oligosaccharide of CD59 and demonstrate that the phospholipid tail is needed for the full functional activity of CD59.	Phospholipids	137-149	CD59 molecule (CD59 blood group)	Homo sapiens	107-111
8670172-13	1996	These results document the structural heterogeneity of both the GPI anchor and N-linked oligosaccharide of CD59 and demonstrate that the phospholipid tail is needed for the full functional activity of CD59.	Phospholipids	137-149	CD59 molecule (CD59 blood group)	Homo sapiens	201-205
8706691-1	1996	The molybdenum-containing iron-sulfur flavoprotein xanthine dehydrogenase from the anaerobic bacterium Veillonella atypica has been purified approximately 800-fold with a yield of approximately 40% and a specific activity of approximately 70 micromol ferricyanide reduced x min(-1) x mg protein(-1) with xanthine as electron donor, which corresponds to approximately 30 micromol xanthine oxidized x min(-1) x mg protein(-1) with methylene blue as electron acceptor.	Xanthine	51-59	CD59 molecule (CD59 blood group)	Homo sapiens	399-405
8650218-5	1996	When the GPI-anchored proteins CD59, CD48, and Thy-1 were immunoprecipitated from various cell lines or freshly isolated lymphocytes, all were found to be associated with a 41-kDa phosphoprotein that we have identified, by using specific antisera, as a mixture of tyrosine phosphorylated G protein alpha subunits: a small amount of Gialpha1, and substantial amounts of Gialpha2 and Gialpha3.	Glycosylphosphatidylinositols	9-12	CD59 molecule (CD59 blood group)	Homo sapiens	31-35
8650218-6	1996	GTP binding assays performed with immunoprecipitations of CD59 indicated that there was GTP-binding activity associated with this molecule.	Guanosine Triphosphate	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	58-62
8650218-6	1996	GTP binding assays performed with immunoprecipitations of CD59 indicated that there was GTP-binding activity associated with this molecule.	Guanosine Triphosphate	88-91	CD59 molecule (CD59 blood group)	Homo sapiens	58-62
8800358-3	1996	With 4% CO2, peak pulmonary ventilation during the exhaustive exercise increased further by 41 L min-1 (140-181 L min-1; P < 0.05) without affecting the handgrip strength.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	8-11	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
8800358-3	1996	With 4% CO2, peak pulmonary ventilation during the exhaustive exercise increased further by 41 L min-1 (140-181 L min-1; P < 0.05) without affecting the handgrip strength.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	8-11	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
8694207-4	1996	The overall mean (SD) urea clearance was 26.6 (6.0) ml.min-1 and the overall creatinine clearance was 30.1 (6.3) ml.min-1.	Creatinine	77-87	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
8694207-6	1996	Creatinine clearance was significantly lower in filters that failed within 24 h (filters < 24 h 27.5 (6.3) ml.min-1; filters > 24 h 32.2 (5.5) ml.min-1).	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
8694207-6	1996	Creatinine clearance was significantly lower in filters that failed within 24 h (filters < 24 h 27.5 (6.3) ml.min-1; filters > 24 h 32.2 (5.5) ml.min-1).	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
8799518-6	1996	of morphine, M3G and M6G were 86 +/- 52 ng ml-1, 703 +/- 400 ng ml-1 and 48 +/- 28 ng ml-1 respectively and morphine clearance was found to be 4.6 +/- 3.2 ml min-1 kg-1.	Morphine	108-116	CD59 molecule (CD59 blood group)	Homo sapiens	158-168
8640974-8	1996	At rest, mean myocardial blood flow was 0.64 +/- 0.09 mL.min-1.g-1 for [13N]ammonia and 0.66 +/- 0.12 mL.min-1.g-1 for [15O]water (P = NS).	Nitrogen-13	72-75	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
8640974-8	1996	At rest, mean myocardial blood flow was 0.64 +/- 0.09 mL.min-1.g-1 for [13N]ammonia and 0.66 +/- 0.12 mL.min-1.g-1 for [15O]water (P = NS).	Ammonia	76-83	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
8640974-9	1996	For adenosine-induced hyperemia, mean myocardial blood flow was 2.63 +/- 0.75 mL.min-1.g-1 for [13N]ammonia and 2.73 +/- 0.77 mL.min-1.g-1 for [15O]water (P = NS).	Adenosine	4-13	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
8640974-9	1996	For adenosine-induced hyperemia, mean myocardial blood flow was 2.63 +/- 0.75 mL.min-1.g-1 for [13N]ammonia and 2.73 +/- 0.77 mL.min-1.g-1 for [15O]water (P = NS).	Adenosine	4-13	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
8640974-9	1996	For adenosine-induced hyperemia, mean myocardial blood flow was 2.63 +/- 0.75 mL.min-1.g-1 for [13N]ammonia and 2.73 +/- 0.77 mL.min-1.g-1 for [15O]water (P = NS).	Nitrogen-13	96-99	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
8640974-9	1996	For adenosine-induced hyperemia, mean myocardial blood flow was 2.63 +/- 0.75 mL.min-1.g-1 for [13N]ammonia and 2.73 +/- 0.77 mL.min-1.g-1 for [15O]water (P = NS).	Ammonia	100-107	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
8641184-9	1996	The [3H]progesterone dissociation rate was 4.52 +/- 0.44 x 10(-3) min-1 at the higher concentrations of hPR-B and was increased to 1.6 +/- 0.11 x 10(-3) min-1 at the lower concentrations.	Tritium	5-7	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
8641184-9	1996	The [3H]progesterone dissociation rate was 4.52 +/- 0.44 x 10(-3) min-1 at the higher concentrations of hPR-B and was increased to 1.6 +/- 0.11 x 10(-3) min-1 at the lower concentrations.	Tritium	5-7	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
8804928-8	1996	Both NO concentration and its output were significantly higher in the steroid-free asthmatic patients (15.6 +/- 1.5 parts per billion (ppb) and 6.3 +/- 0.7 nmol.min-1, respectively) as compared with the control subjects (8.9 +/- 1.0 ppb and 3.5 +/- 0.3 nmol.min-1, respectively; p < 0.001 for both) and with the steroid-treated asthmatic patients (11.3 +/- 3.3 ppb and 3.7 +/- 0.9 nmol.min-1, respectively; p < 0.05 for both).	Steroids	70-77	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
8804928-8	1996	Both NO concentration and its output were significantly higher in the steroid-free asthmatic patients (15.6 +/- 1.5 parts per billion (ppb) and 6.3 +/- 0.7 nmol.min-1, respectively) as compared with the control subjects (8.9 +/- 1.0 ppb and 3.5 +/- 0.3 nmol.min-1, respectively; p < 0.001 for both) and with the steroid-treated asthmatic patients (11.3 +/- 3.3 ppb and 3.7 +/- 0.9 nmol.min-1, respectively; p < 0.05 for both).	Steroids	70-77	CD59 molecule (CD59 blood group)	Homo sapiens	258-263
8804928-8	1996	Both NO concentration and its output were significantly higher in the steroid-free asthmatic patients (15.6 +/- 1.5 parts per billion (ppb) and 6.3 +/- 0.7 nmol.min-1, respectively) as compared with the control subjects (8.9 +/- 1.0 ppb and 3.5 +/- 0.3 nmol.min-1, respectively; p < 0.001 for both) and with the steroid-treated asthmatic patients (11.3 +/- 3.3 ppb and 3.7 +/- 0.9 nmol.min-1, respectively; p < 0.05 for both).	Steroids	70-77	CD59 molecule (CD59 blood group)	Homo sapiens	258-263
8667222-7	1996	The apparent elimination rate constant (Kel) of [3H]3-O-methyl-D-glucose from the brain was determined as 0.129 +/- 0.014 (min-1) and was reduced significantly by a preinjection of excess cold 3-O-methyl-D-glucose and phloridzin, whereas no significant elimination was observed for L[3H]glucose.	Tritium	48-52	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8667222-7	1996	The apparent elimination rate constant (Kel) of [3H]3-O-methyl-D-glucose from the brain was determined as 0.129 +/- 0.014 (min-1) and was reduced significantly by a preinjection of excess cold 3-O-methyl-D-glucose and phloridzin, whereas no significant elimination was observed for L[3H]glucose.	3-O-Methylglucose	52-72	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8667222-7	1996	The apparent elimination rate constant (Kel) of [3H]3-O-methyl-D-glucose from the brain was determined as 0.129 +/- 0.014 (min-1) and was reduced significantly by a preinjection of excess cold 3-O-methyl-D-glucose and phloridzin, whereas no significant elimination was observed for L[3H]glucose.	3-O-Methylglucose	193-213	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8637453-6	1996	However, glycerol and palmitate Ra values (3.11 +/- 0.30 and 2.01 +/- 0.33 micromol x kg(-1) x min(-1), respectively) were 25% higher than values observed previously in normal subjects.	Glycerol	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	95-101
8637453-6	1996	However, glycerol and palmitate Ra values (3.11 +/- 0.30 and 2.01 +/- 0.33 micromol x kg(-1) x min(-1), respectively) were 25% higher than values observed previously in normal subjects.	Palmitates	22-31	CD59 molecule (CD59 blood group)	Homo sapiens	95-101
8800366-6	1996	The metabolic clearance rate of glucose (MCR) for the diabetic rats receiving C-peptide (12.0 +/- 1.0 mL kg-1 min-1) was significantly (P < 0.01) higher than that in the diabetic rats given saline (6.3 +/- 0.7 mL kg-1 min-1) or a randomly scrambled C-peptide (7.8 +/- 1.3 mL kg-1 min-1) at low-dose insulin infusion but not at the high-dose insulin infusion.	Glucose	32-39	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
8800366-6	1996	The metabolic clearance rate of glucose (MCR) for the diabetic rats receiving C-peptide (12.0 +/- 1.0 mL kg-1 min-1) was significantly (P < 0.01) higher than that in the diabetic rats given saline (6.3 +/- 0.7 mL kg-1 min-1) or a randomly scrambled C-peptide (7.8 +/- 1.3 mL kg-1 min-1) at low-dose insulin infusion but not at the high-dose insulin infusion.	Glucose	32-39	CD59 molecule (CD59 blood group)	Homo sapiens	221-226
8800366-6	1996	The metabolic clearance rate of glucose (MCR) for the diabetic rats receiving C-peptide (12.0 +/- 1.0 mL kg-1 min-1) was significantly (P < 0.01) higher than that in the diabetic rats given saline (6.3 +/- 0.7 mL kg-1 min-1) or a randomly scrambled C-peptide (7.8 +/- 1.3 mL kg-1 min-1) at low-dose insulin infusion but not at the high-dose insulin infusion.	Glucose	32-39	CD59 molecule (CD59 blood group)	Homo sapiens	221-226
8832584-2	1996	Both noradrenaline and methoxamine produced dose-dependent venoconstriction; the geometric mean ED50 for noradrenaline was 4.15 ng min-1 and for methoxamine was 1143.54 ng min-1; the potency ratio (noradrenaline/methoxamine) was 277.	Norepinephrine	5-18	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8832584-2	1996	Both noradrenaline and methoxamine produced dose-dependent venoconstriction; the geometric mean ED50 for noradrenaline was 4.15 ng min-1 and for methoxamine was 1143.54 ng min-1; the potency ratio (noradrenaline/methoxamine) was 277.	Methoxamine	23-34	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8832584-2	1996	Both noradrenaline and methoxamine produced dose-dependent venoconstriction; the geometric mean ED50 for noradrenaline was 4.15 ng min-1 and for methoxamine was 1143.54 ng min-1; the potency ratio (noradrenaline/methoxamine) was 277.	Norepinephrine	5-18	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
8832584-2	1996	Both noradrenaline and methoxamine produced dose-dependent venoconstriction; the geometric mean ED50 for noradrenaline was 4.15 ng min-1 and for methoxamine was 1143.54 ng min-1; the potency ratio (noradrenaline/methoxamine) was 277.	Methoxamine	23-34	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
8832584-2	1996	Both noradrenaline and methoxamine produced dose-dependent venoconstriction; the geometric mean ED50 for noradrenaline was 4.15 ng min-1 and for methoxamine was 1143.54 ng min-1; the potency ratio (noradrenaline/methoxamine) was 277.	Norepinephrine	105-118	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8832584-2	1996	Both noradrenaline and methoxamine produced dose-dependent venoconstriction; the geometric mean ED50 for noradrenaline was 4.15 ng min-1 and for methoxamine was 1143.54 ng min-1; the potency ratio (noradrenaline/methoxamine) was 277.	Methoxamine	145-156	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
8832584-2	1996	Both noradrenaline and methoxamine produced dose-dependent venoconstriction; the geometric mean ED50 for noradrenaline was 4.15 ng min-1 and for methoxamine was 1143.54 ng min-1; the potency ratio (noradrenaline/methoxamine) was 277.	Norepinephrine	105-118	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8832584-2	1996	Both noradrenaline and methoxamine produced dose-dependent venoconstriction; the geometric mean ED50 for noradrenaline was 4.15 ng min-1 and for methoxamine was 1143.54 ng min-1; the potency ratio (noradrenaline/methoxamine) was 277.	Methoxamine	145-156	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
8660102-5	1996	Transient cytosolic calcium ion fluxes were observed after binding Fc gamma RII, Fc gamma RIII, or CD59 with specific monoclonal antibodies and cross linking with the F(ab)2 fragment of sheep antimouse IgG.	Calcium	20-27	CD59 molecule (CD59 blood group)	Homo sapiens	99-103
18966556-7	1996	Aldehydes in sample gas (10 1) were collected by passing the gas at a flow rate of 0.5 1 min(-1) through two impingers connected in series.	Aldehydes	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
8639648-7	1996	High redox state did not affect TCA cycle flux but increased the rate of interconversion between alpha-ketoglutarate and glutamate from 3.1 +/- 0.2 mumol min-1 (g dry)-1 to 14.3 +/- 2.0.	Ketoglutaric Acids	97-116	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
8639648-7	1996	High redox state did not affect TCA cycle flux but increased the rate of interconversion between alpha-ketoglutarate and glutamate from 3.1 +/- 0.2 mumol min-1 (g dry)-1 to 14.3 +/- 2.0.	Glutamic Acid	121-130	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
8967440-4	1996	MK-801 (500 microM) reduced the maximal velocity for glutamate uptake in astrocytes from 31 to 17 nmol.mg protein-1.min-1, whereas competitive NMDA receptor antagonists did not affect glutamate uptake.	Dizocilpine Maleate	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
8967440-4	1996	MK-801 (500 microM) reduced the maximal velocity for glutamate uptake in astrocytes from 31 to 17 nmol.mg protein-1.min-1, whereas competitive NMDA receptor antagonists did not affect glutamate uptake.	Glutamic Acid	53-62	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
8688264-3	1996	Mean nitric oxide uptake was 0.49 (SD 0.08) ml min-1 at standard temperature and pressure, corresponding to 74% of the inhaled dose.	Nitric Oxide	5-17	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
8737024-3	1996	Whole blood glucose concentrations were measured contemporaneously and the rate of plasma glucose decline (mmol l-1 min-1) for each test was estimated from unlogged venous plasma glucose concentrations measured at 1 min intervals.	Glucose	90-97	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
8737024-3	1996	Whole blood glucose concentrations were measured contemporaneously and the rate of plasma glucose decline (mmol l-1 min-1) for each test was estimated from unlogged venous plasma glucose concentrations measured at 1 min intervals.	Glucose	90-97	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
8737024-4	1996	The mean rates of plasma glucose decline for the 0.1 U kg-1 and 0.05 U kg-1 insulin doses were 0.26 mmol l-1 min-1 (n = 11, range = 0.17-0.41, intrasubject coefficient of variation (CV) = 9.4%) and 0.25 mmol l-1 min-1 (n = 6, range 0.19-0.46, intrasubject CV = 15.9%), respectively.	Glucose	25-32	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
8737076-3	1996	Dopamine, noradrenaline and adrenaline enter the red blood cell by a similar process, which shows saturation kinetics with Vmax values of 0.54 +/- 0.12, 0.48 +/- 0.08 and 0.63 +/- 0.13 mumol (1 cells)-1 min-1, respectively, and K(m) values of 15.62 +/- 1.19, 5.81 +/- 1.19 and 12.00 +/- 2.97 nM, respectively.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
8737076-3	1996	Dopamine, noradrenaline and adrenaline enter the red blood cell by a similar process, which shows saturation kinetics with Vmax values of 0.54 +/- 0.12, 0.48 +/- 0.08 and 0.63 +/- 0.13 mumol (1 cells)-1 min-1, respectively, and K(m) values of 15.62 +/- 1.19, 5.81 +/- 1.19 and 12.00 +/- 2.97 nM, respectively.	Norepinephrine	10-23	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
8737076-3	1996	Dopamine, noradrenaline and adrenaline enter the red blood cell by a similar process, which shows saturation kinetics with Vmax values of 0.54 +/- 0.12, 0.48 +/- 0.08 and 0.63 +/- 0.13 mumol (1 cells)-1 min-1, respectively, and K(m) values of 15.62 +/- 1.19, 5.81 +/- 1.19 and 12.00 +/- 2.97 nM, respectively.	Epinephrine	13-23	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
8621747-4	1996	The fit of the integrated symmetric Michaelis-Menten model to the time course of relative glucose signals yielded an estimated plasma glucose concentration for half maximal transport, Kt, of 4.8 +/- 2.4 mM (mean +/- SD), a maximal transport rate, Tmax, of 0.80 +/- 0.45 micromol g-1 min-1, and a cerebral metabolic glucose consumption rate (CMR)glc of 0.32 +/- 0.16 micromol g-1 min-1.	Glucose	134-141	CD59 molecule (CD59 blood group)	Homo sapiens	283-288
8621747-4	1996	The fit of the integrated symmetric Michaelis-Menten model to the time course of relative glucose signals yielded an estimated plasma glucose concentration for half maximal transport, Kt, of 4.8 +/- 2.4 mM (mean +/- SD), a maximal transport rate, Tmax, of 0.80 +/- 0.45 micromol g-1 min-1, and a cerebral metabolic glucose consumption rate (CMR)glc of 0.32 +/- 0.16 micromol g-1 min-1.	Glucose	134-141	CD59 molecule (CD59 blood group)	Homo sapiens	379-384
8621747-5	1996	Assuming cerebral glucose concentration to be 1.0 micromol/g at euglycemia as measured by 13CMR, the fit of the same model to the time course of brain glucose concentrations resulted in Kt = 3.9 +/- 0.82 mM, Tmax = 1.16 +/- 0.29 micromol g-1 min-1, and CMRglc = 0.35 +/- 0.10 micromol g-1 min-1.	Glucose	18-25	CD59 molecule (CD59 blood group)	Homo sapiens	242-247
8621747-5	1996	Assuming cerebral glucose concentration to be 1.0 micromol/g at euglycemia as measured by 13CMR, the fit of the same model to the time course of brain glucose concentrations resulted in Kt = 3.9 +/- 0.82 mM, Tmax = 1.16 +/- 0.29 micromol g-1 min-1, and CMRglc = 0.35 +/- 0.10 micromol g-1 min-1.	Glucose	18-25	CD59 molecule (CD59 blood group)	Homo sapiens	289-294
8621747-5	1996	Assuming cerebral glucose concentration to be 1.0 micromol/g at euglycemia as measured by 13CMR, the fit of the same model to the time course of brain glucose concentrations resulted in Kt = 3.9 +/- 0.82 mM, Tmax = 1.16 +/- 0.29 micromol g-1 min-1, and CMRglc = 0.35 +/- 0.10 micromol g-1 min-1.	Glucose	151-158	CD59 molecule (CD59 blood group)	Homo sapiens	242-247
8621747-5	1996	Assuming cerebral glucose concentration to be 1.0 micromol/g at euglycemia as measured by 13CMR, the fit of the same model to the time course of brain glucose concentrations resulted in Kt = 3.9 +/- 0.82 mM, Tmax = 1.16 +/- 0.29 micromol g-1 min-1, and CMRglc = 0.35 +/- 0.10 micromol g-1 min-1.	Glucose	151-158	CD59 molecule (CD59 blood group)	Homo sapiens	289-294
8666664-4	1996	Here, we show that the GPI-anchored CD59 molecule on Jurkat T cells is internalized after cross-linking, a process inhibited by nystatin, a sterol chelating agent.	Glycosylphosphatidylinositols	23-26	CD59 molecule (CD59 blood group)	Homo sapiens	36-40
8666664-4	1996	Here, we show that the GPI-anchored CD59 molecule on Jurkat T cells is internalized after cross-linking, a process inhibited by nystatin, a sterol chelating agent.	Nystatin	128-136	CD59 molecule (CD59 blood group)	Homo sapiens	36-40
8666664-4	1996	Here, we show that the GPI-anchored CD59 molecule on Jurkat T cells is internalized after cross-linking, a process inhibited by nystatin, a sterol chelating agent.	Sterols	140-146	CD59 molecule (CD59 blood group)	Homo sapiens	36-40
8666664-6	1996	Cytochalasin H blocked CD59 internalization in lymphocytes, but neither CD3 internalization nor transferrin uptake.	cytochalasin H	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	23-27
8666664-8	1996	Also, we found that internalization of CD59 was prevented by the protein kinase C inhibitor staurosporine and by the protein kinase A activator forskolin.	Staurosporine	92-105	CD59 molecule (CD59 blood group)	Homo sapiens	39-43
8666664-8	1996	Also, we found that internalization of CD59 was prevented by the protein kinase C inhibitor staurosporine and by the protein kinase A activator forskolin.	Colforsin	144-153	CD59 molecule (CD59 blood group)	Homo sapiens	39-43
8642232-8	1996	Forearm blood flow (plethysmography) was lower with metoprolol compared to enalaprilat (2.1 +/- 0.2 vs. 2.8 +/- 0.4 mL per 100 mL min-1; P < 0.05).	Metoprolol	52-62	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
8799880-3	1996	The doses of phenylephrine required to increase systolic blood pressure by 20 mmHg after 8 and 12 h (5.30 and 9.30 pm, 81.4 +/- 15.3 and 71.1 +/- 16.0 micrograms min-1, respectively) were significantly (P < 0.01) less than the baseline values (8.30 am, 108.0 +/- 27.6 g min-1).	Phenylephrine	13-26	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
8799880-3	1996	The doses of phenylephrine required to increase systolic blood pressure by 20 mmHg after 8 and 12 h (5.30 and 9.30 pm, 81.4 +/- 15.3 and 71.1 +/- 16.0 micrograms min-1, respectively) were significantly (P < 0.01) less than the baseline values (8.30 am, 108.0 +/- 27.6 g min-1).	Phenylephrine	13-26	CD59 molecule (CD59 blood group)	Homo sapiens	273-278
8847783-5	1996	Fourteen patients who received PG 0.02 micrograms.kg-1.min-1 were defined as a PG group.	Alprostadil	79-81	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
8735680-18	1996	Patients with less than 30 ml min-1 creatinine clearance may require less frequent administration of transnasal butorphanol as compared with subjects with normal or moderately impaired renal function.	Creatinine	36-46	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
8735519-6	1996	The average mean infusion rate of propofol was 0.136 mg kg-1 min-1, and the ketamine infusion rate was maintained at 50 micrograms kg-1 min-1.	Ketamine	76-84	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
8735680-18	1996	Patients with less than 30 ml min-1 creatinine clearance may require less frequent administration of transnasal butorphanol as compared with subjects with normal or moderately impaired renal function.	Butorphanol	112-123	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
8678058-3	1996	We report a double-blind study of the effect of 5 mg enalapril once daily compared with placebo in patients with nondiabetic severe chronic renal impairment (plasma creatinine 2.8 to 6.8 mg/dL; mean creatinine clearance 15 mL/min/1.73 m2) followed for up to 2 years.	Enalapril	53-62	CD59 molecule (CD59 blood group)	Homo sapiens	226-231
8611518-8	1996	The pseudo-first-order rate constants for cleavage of the thio analogue in the presence of 10 mM Mg2+ or Mn2+ at pH 7.5 are 65 and 82 x 10(-3) min-1, respectively.	thio	58-62	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
8611518-8	1996	The pseudo-first-order rate constants for cleavage of the thio analogue in the presence of 10 mM Mg2+ or Mn2+ at pH 7.5 are 65 and 82 x 10(-3) min-1, respectively.	Manganese(2+)	105-109	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
8611518-9	1996	The native oxo linkage is cleaved at essentially the same rate as the thio analogue (35 and 97 x 10(-3) min-1 for Mg2+ and Mn2+, respectively).	thio	70-74	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
8967393-4	1996	During the first 5 min of incubation, adenosine production in slices (n = 5) equaled 26 +/- 10 (SD) nmol.min-1.g wet wt-1, and total AMP content was 0.81 +/- 0.46 mM.	Adenosine	38-47	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
8724787-4	1996	The rate of decarbamylation of acetylcholinesterase inhibited by aminostigmine measured by the dilution method, by creating excessive acetylcholine and by dialysis is characterized by k2c constants equal to (1.1-1.6).10(-2), (2.5-2.8).10(-2) and 0.025.10(-2) min-1, respectively.	aminostigmine	65-78	CD59 molecule (CD59 blood group)	Homo sapiens	259-264
8724787-4	1996	The rate of decarbamylation of acetylcholinesterase inhibited by aminostigmine measured by the dilution method, by creating excessive acetylcholine and by dialysis is characterized by k2c constants equal to (1.1-1.6).10(-2), (2.5-2.8).10(-2) and 0.025.10(-2) min-1, respectively.	Acetylcholine	31-44	CD59 molecule (CD59 blood group)	Homo sapiens	259-264
8730974-17	1996	The regression model for fluconazole clearance that accounted for changes in renal function and disease severity was CL (l h-1) = 0.25 (33%) + 0.0057 (32%) x CLcr (in ml min-1) + 0.00068 (10%) x CD4 cell count (in cells mm-3) where intersubject variability (expressed as %CV) is shown in brackets.	Fluconazole	25-36	CD59 molecule (CD59 blood group)	Homo sapiens	170-175
8726952-2	1996	We investigated the oxygen concentration received when oxygen was supplied at flow rates between 0 and 6 L.min-1 into the proximal ventilator tubing or the nasal mask whilst patients were ventilated with air.	Oxygen	20-26	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
8638836-9	1996	The NONMEM analysis population pharmacokinetic parameters for remifentanil include a CLc of 2.9 l x min(-1), a VDss of 21.81, and a terminal half-life of 35.1 min.	Remifentanil	62-74	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
8638836-10	1996	Corresponding NONMEM parameters for alfentanil are 0.36 l x min(-1), 34.11, and 94.5 min.	Alfentanil	36-46	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
8638839-9	1996	DCA clearance was 0.997, 0.0, and 1.69 ml x kg(-1) x min(-1) during the paleohepatic, anhepatic, and neohepatic periods, respectively (P < 0.05).	Dichloroacetic Acid	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	53-59
8738336-5	1996	Its hydrolysis constant (0.008 L mol-1 min-1), as a free monomer, in an alkaline milieu, was found to be about one order of magnitude lower than conventional acrylamide (0.05 L mol-1 min-1).	Acrylamide	158-168	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
8726952-2	1996	We investigated the oxygen concentration received when oxygen was supplied at flow rates between 0 and 6 L.min-1 into the proximal ventilator tubing or the nasal mask whilst patients were ventilated with air.	Oxygen	55-61	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
8733098-6	1996	Heart rate (rest: 68 +/- 13 beats.min-1) was also unchanged after dipyridamole (69 +/- 12, P = ns vs rest) and increased slightly after dobutamine (71 +/- 15, P < 0.05 vs rest and vs dipyridamole).	Dipyridamole	186-198	CD59 molecule (CD59 blood group)	Homo sapiens	34-39
8726952-9	1996	However, there was no significant difference between the two routes in the inspired oxygen concentration achieved at all flow rates: 1 L.min-1 supplied approximately 31% oxygen; 2 L.min-1 37%; 3 L.min-1 40%; and 4 L.min-1 44%.	Oxygen	170-176	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
8609836-7	1996	After steroids, insulin sensitivity decreased from 6.00 +/- 1.29 to 4.23 +/- 1.04 min-1/(microU/mL) (P < .04).	Steroids	6-14	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
8609904-6	1996	2,2",3,5",6-Pentachlorobiphenyl induces a dose-dependent release of Ca2+ from actively loaded SR vesicles with a maximum rate of 1.2 micromol mg-1 min-1 (EC50=1 microM), whereas 3,3",4,4",5-pentachlorobiphenyl (< / = microM) does not alter Ca2+ transport.	2,2',3,5',6-pentachlorobiphenyl	0-31	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
8848343-7	1996	Calcium absorption from the glucose polymer solution was greater than that from the control and lactose solutions (0.17 +/- 0.05 mumol.min-1.cm-1 versus 0.04 +/- 0.04 and 0.008 +/- 0.045 mumol.min-1.cm-1, respectively).	Calcium	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
8848343-7	1996	Calcium absorption from the glucose polymer solution was greater than that from the control and lactose solutions (0.17 +/- 0.05 mumol.min-1.cm-1 versus 0.04 +/- 0.04 and 0.008 +/- 0.045 mumol.min-1.cm-1, respectively).	Calcium	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
8848343-7	1996	Calcium absorption from the glucose polymer solution was greater than that from the control and lactose solutions (0.17 +/- 0.05 mumol.min-1.cm-1 versus 0.04 +/- 0.04 and 0.008 +/- 0.045 mumol.min-1.cm-1, respectively).	Glucans	28-43	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
8848343-7	1996	Calcium absorption from the glucose polymer solution was greater than that from the control and lactose solutions (0.17 +/- 0.05 mumol.min-1.cm-1 versus 0.04 +/- 0.04 and 0.008 +/- 0.045 mumol.min-1.cm-1, respectively).	Glucans	28-43	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
8848343-9	1996	The rate of carbohydrate absorption was greater from the glucose polymers than from the lactose solution (0.40 +/- 0.10 mg.min-1.cm-1 versus 0.22 +/- 0.06, respectively).	Carbohydrates	12-24	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8866925-2	1996	Serotonin was infused in five incremental doses (0.003-30 micrograms min-1) for 2 min each into the brachial artery of the non-dominant forearm.	Serotonin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
8736653-7	1996	Mean morning PEF was 426 l min-1 during terbutaline and 410 l min-1 during salbutamol (difference 16 l min-1, 95% CI of difference 3-28 l min-1, P = 0.016), and mean evening PEF was 446 l min-1 during terbutaline and 428 l min-1 during salbutamol (difference 18 l min-1, 95% CI 5-30 l min-1, P = 0.0076).	Albuterol	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8736653-7	1996	Mean morning PEF was 426 l min-1 during terbutaline and 410 l min-1 during salbutamol (difference 16 l min-1, 95% CI of difference 3-28 l min-1, P = 0.016), and mean evening PEF was 446 l min-1 during terbutaline and 428 l min-1 during salbutamol (difference 18 l min-1, 95% CI 5-30 l min-1, P = 0.0076).	Albuterol	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8736653-7	1996	Mean morning PEF was 426 l min-1 during terbutaline and 410 l min-1 during salbutamol (difference 16 l min-1, 95% CI of difference 3-28 l min-1, P = 0.016), and mean evening PEF was 446 l min-1 during terbutaline and 428 l min-1 during salbutamol (difference 18 l min-1, 95% CI 5-30 l min-1, P = 0.0076).	Albuterol	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8736653-7	1996	Mean morning PEF was 426 l min-1 during terbutaline and 410 l min-1 during salbutamol (difference 16 l min-1, 95% CI of difference 3-28 l min-1, P = 0.016), and mean evening PEF was 446 l min-1 during terbutaline and 428 l min-1 during salbutamol (difference 18 l min-1, 95% CI 5-30 l min-1, P = 0.0076).	Albuterol	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8736653-7	1996	Mean morning PEF was 426 l min-1 during terbutaline and 410 l min-1 during salbutamol (difference 16 l min-1, 95% CI of difference 3-28 l min-1, P = 0.016), and mean evening PEF was 446 l min-1 during terbutaline and 428 l min-1 during salbutamol (difference 18 l min-1, 95% CI 5-30 l min-1, P = 0.0076).	Albuterol	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8736653-7	1996	Mean morning PEF was 426 l min-1 during terbutaline and 410 l min-1 during salbutamol (difference 16 l min-1, 95% CI of difference 3-28 l min-1, P = 0.016), and mean evening PEF was 446 l min-1 during terbutaline and 428 l min-1 during salbutamol (difference 18 l min-1, 95% CI 5-30 l min-1, P = 0.0076).	Albuterol	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8736653-7	1996	Mean morning PEF was 426 l min-1 during terbutaline and 410 l min-1 during salbutamol (difference 16 l min-1, 95% CI of difference 3-28 l min-1, P = 0.016), and mean evening PEF was 446 l min-1 during terbutaline and 428 l min-1 during salbutamol (difference 18 l min-1, 95% CI 5-30 l min-1, P = 0.0076).	Albuterol	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8623155-3	1996	Insulin-stimulated glucose disposal was reduced by 33% in kidney transplant patients compared with healthy controls (33.8 +/- 4.2 vs. 50.5 +/- 2.7 mumol (kg LBM)-1 min-1; P<0.01), primarily due to a decrease in nonoxidative glucose metabolism (14.2 +/- 3.3 vs. 32.3 +/- 2.7 mumol (kg LBM)-1 min-1; P<0.001).	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
8623155-3	1996	Insulin-stimulated glucose disposal was reduced by 33% in kidney transplant patients compared with healthy controls (33.8 +/- 4.2 vs. 50.5 +/- 2.7 mumol (kg LBM)-1 min-1; P<0.01), primarily due to a decrease in nonoxidative glucose metabolism (14.2 +/- 3.3 vs. 32.3 +/- 2.7 mumol (kg LBM)-1 min-1; P<0.001).	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	294-299
8615796-0	1996	Mechanisms by which the surface expression of the glycosyl-phosphatidylinositol-anchored complement regulatory proteins decay-accelerating factor (CD55) and CD59 is lost in human leukaemia cell lines.	Glycosylphosphatidylinositols	50-79	CD59 molecule (CD59 blood group)	Homo sapiens	157-161
8605162-0	1996	Role of a disulfide-bonded peptide loop within human complement C9 in the species-selectivity of complement inhibitor CD59.	Disulfides	10-19	CD59 molecule (CD59 blood group)	Homo sapiens	118-122
8621438-3	1996	When ATP is hydrolyzed, the extension phase is progressive and its rate is 380 +/- 20 bp min-1 at 37 degrees C. A single RecA nucleoprotein filament can participate in multiple DNA strand exchange reactions concurrently (involving duplex DNA fragments that are homologous to different segments of the DNA within a nucleoprotein filament), with no effect on the observed rate of ATP hydrolysis.	Adenosine Triphosphate	5-8	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
8621438-7	1996	The rate of branch movement in the extension phase (base pair min-1) is related to the kcat for ATP hydrolysis during strand exchange (min-1) by a factor equivalent to 18 bp throughout the temperature range examined.	Adenosine Triphosphate	96-99	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8621438-7	1996	The rate of branch movement in the extension phase (base pair min-1) is related to the kcat for ATP hydrolysis during strand exchange (min-1) by a factor equivalent to 18 bp throughout the temperature range examined.	Adenosine Triphosphate	96-99	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
8866925-6	1996	Serotonin caused a biphasic response with vasodilatation occurring at low doses (0.003-3 micrograms min-1, P < 0.01) and vasoconstriction occurring at the highest dose (P < 0.01).	Serotonin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
8593934-6	1996	Whole-body glucose uptake was 58% decreased in patients with NIDDM (20 +/- 3 micromol x kg body wt-1 x min-1) compared with normal subjects (47 +/- 4 micromol x kg body wt-1 x min-1, P < 0.001).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
8907251-3	1996	The observed rate consists of a high affinity (apparent Km 7 mu M, Vmax 3 center dot 25 pmol min-1 (10(6) cells)-1 and a low affinity component, which was non-saturable up to 1 mM of DHA (rate increase of 0 center dot 1 pmol min-1 (10(6) cells)-1 (1 mu M of DHA-1).	dehydroacetic acid	183-186	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8907251-3	1996	The observed rate consists of a high affinity (apparent Km 7 mu M, Vmax 3 center dot 25 pmol min-1 (10(6) cells)-1 and a low affinity component, which was non-saturable up to 1 mM of DHA (rate increase of 0 center dot 1 pmol min-1 (10(6) cells)-1 (1 mu M of DHA-1).	dehydroacetic acid	183-186	CD59 molecule (CD59 blood group)	Homo sapiens	225-230
8907251-3	1996	The observed rate consists of a high affinity (apparent Km 7 mu M, Vmax 3 center dot 25 pmol min-1 (10(6) cells)-1 and a low affinity component, which was non-saturable up to 1 mM of DHA (rate increase of 0 center dot 1 pmol min-1 (10(6) cells)-1 (1 mu M of DHA-1).	dehydroacetic acid	258-261	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8907251-5	1996	Although uptake of DHA proceeded at a higher rate than its extracellular reduction, the generation of extracellular ascorbate from DHA cannot be accounted for by intracellular reduction and the release of ascorbate, since the latter was not linear with time and had an initial rate of approximately 3 pmol min-1 (10(6) cells-1).	Ascorbic Acid	116-125	CD59 molecule (CD59 blood group)	Homo sapiens	306-311
8593939-7	1996	Glucose disposal (1 mU x kg-1 x min-1) euglycemic insulin clamp with D-[3(-3)H]glucose) was higher in the normal glucose tolerance group compared with the impaired and diabetic groups (37.8 +/- 10.2 vs. 26.1 +/- 10.7 and 26.7 +/- 12.0 micromol x kg-1 x min-1; P < 0.05) despite similar BMIs in all three groups (28.8 +/- 3.7 kg/m2).	d-[3(-3)h]glucose	69-86	CD59 molecule (CD59 blood group)	Homo sapiens	32-37
8593934-6	1996	Whole-body glucose uptake was 58% decreased in patients with NIDDM (20 +/- 3 micromol x kg body wt-1 x min-1) compared with normal subjects (47 +/- 4 micromol x kg body wt-1 x min-1, P < 0.001).	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
8593939-7	1996	Glucose disposal (1 mU x kg-1 x min-1) euglycemic insulin clamp with D-[3(-3)H]glucose) was higher in the normal glucose tolerance group compared with the impaired and diabetic groups (37.8 +/- 10.2 vs. 26.1 +/- 10.7 and 26.7 +/- 12.0 micromol x kg-1 x min-1; P < 0.05) despite similar BMIs in all three groups (28.8 +/- 3.7 kg/m2).	Glucose	79-86	CD59 molecule (CD59 blood group)	Homo sapiens	32-37
8671618-4	1996	In the two patients that were tested, the GPI-anchored surface molecules CD55 and CD59 were also absent on the CD52- cells, although expression of other cell surface transmembrane, proteins (CD3, CD4 and CD2) was unaffected.	Glycosylphosphatidylinositols	42-45	CD59 molecule (CD59 blood group)	Homo sapiens	82-86
8904347-10	1996	In the diabetic patients, adenosine infusion raised forearm blood flow to 2 center dot 4 +/- 0 center dot 4, 2 center dot 6 +/- 0 center dot 4, 4 center dot 4 +/- 0 center dot 7, 6 center dot 3 +/- 1 center dot 0, 9 center dot 8 +/- 1 center dot 5 and 14 center dot 2 +/- 2 center dot mL 100(-1) mL min-1 for the respective dosages.	Adenosine	26-35	CD59 molecule (CD59 blood group)	Homo sapiens	299-304
9238677-7	1996	All of the post-testicularly acquired GPI-anchored proteins identified thus far have also been found on cells of the immune system (CD62, CD55, CD59, CD73), and we speculate that they may have a role in protecting spermatozoa from immune attack in the male and female reproductive tracts.	Glycosylphosphatidylinositols	38-41	CD59 molecule (CD59 blood group)	Homo sapiens	144-148
8866876-8	1996	In another trial (120 min duration), adrenaline was infused (AI) at 0.1 microgram kg-1 min-1 and plasma catecholamine levels were elevated 6 pmol ml-1 above SI during the 60-120 min period.	Epinephrine	37-47	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
8838433-12	1996	Diltiazem (n = 14) lowered day systolic blood pressure by 13 +/- 2 mmHg, diastolic blood pressure by 11 +/- 2 mmHg and heart rate by 10 +/- 2 beats min-1.	Diltiazem	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
8660301-7	1996	Initial rate kinetic parameters of the native enzyme were 2.0 nM, 0.58 microM and 3 min-1 for KmDNA, KmAdoMet and kcat.	kmadomet	101-109	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
8576911-16	1996	The reactivation of enzyme inhibited by 3-hydrazinopropionate was first order with a rate constant of 6.9 x 10(-3) min-1.	3-hydrazinopropionate	40-61	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
8777098-3	1996	Sufentanil 50 micrograms min-1 was given over 10 min by a constant rate infusion.	Sufentanil	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	25-30
8829879-12	1996	VO2 increased more with dobutamine than with nitroprusside (from 138 +/- 14 to 149 +/- 20 ml min-1 m-2, P < 0.001, and from 131 +/- 14 to 138 +/- 17 ml min-1 m-2, P < 0.001, respectively).	Dobutamine	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
8829879-12	1996	VO2 increased more with dobutamine than with nitroprusside (from 138 +/- 14 to 149 +/- 20 ml min-1 m-2, P < 0.001, and from 131 +/- 14 to 138 +/- 17 ml min-1 m-2, P < 0.001, respectively).	Nitroprusside	45-58	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8829879-13	1996	However, DO2 also increased more with dobutamine than with nitroprusside (from 531 +/- 186 to 702 +/- 274 ml min-1 m-2, P < 0.001, and from 523 +/- 107 to 610 +/- 122 ml min-1 m-2, P < 0.001, respectively).	do2	9-12	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
8829879-13	1996	However, DO2 also increased more with dobutamine than with nitroprusside (from 531 +/- 186 to 702 +/- 274 ml min-1 m-2, P < 0.001, and from 523 +/- 107 to 610 +/- 122 ml min-1 m-2, P < 0.001, respectively).	Dobutamine	38-48	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
8829879-13	1996	However, DO2 also increased more with dobutamine than with nitroprusside (from 531 +/- 186 to 702 +/- 274 ml min-1 m-2, P < 0.001, and from 523 +/- 107 to 610 +/- 122 ml min-1 m-2, P < 0.001, respectively).	Nitroprusside	59-72	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
8833716-7	1996	The corresponding R(2) values for VO in ml.kg(-1).min(-1) were 0.50-0.58.	Vanadium(II) oxide	34-36	CD59 molecule (CD59 blood group)	Homo sapiens	50-56
8929749-8	1996	The dialysis clearance of vancomycin ranged from 50.6 ml.min-1 to 76.8 ml.min-1 (average: 62.4 +/- 10.4 ml.min-1.	Vancomycin	26-36	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
8929749-8	1996	The dialysis clearance of vancomycin ranged from 50.6 ml.min-1 to 76.8 ml.min-1 (average: 62.4 +/- 10.4 ml.min-1.	Vancomycin	26-36	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
8929749-8	1996	The dialysis clearance of vancomycin ranged from 50.6 ml.min-1 to 76.8 ml.min-1 (average: 62.4 +/- 10.4 ml.min-1.	Vancomycin	26-36	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
8929749-10	1996	In accordance to our kinetic study 1 g of vancomycin given every 7 days is adequate treatment for methicillin-resistant Staphylococcus aureus infections in patients with severe renal failure whose creatinine clearance is lower than 10 ml.min-1.	Vancomycin	42-52	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
8583814-3	1996	Dobutamine infusion was started at a rate of 5 micrograms.kg-1.min-1 and increased to 10 and 20 micrograms.kg-1.min-1 at 15-minute intervals.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
8865706-5	1996	3 l. min(-1) oxygen inhalation through the face mask was enough to avoid postoperative hypoxemia in both groups; the mean values of Spo2 were 99% in G group and 97.9% in E group.	Oxygen	13-19	CD59 molecule (CD59 blood group)	Homo sapiens	5-11
8865706-9	1996	In conclusion, there is a high incidence of postoperative hypoxemia for several hours in the ward, which can be relieved by 3 l. min(-1) oxygen inhalation with face mask.	Oxygen	137-143	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
8692288-5	1996	In Session II, venoconstrictor dose-response curves to six doses (0.1-33.33 ng min-1) of (-)noradrenaline acid tartrate were established at congestion pressures 30 and 45 mmHg.	Norepinephrine	92-119	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
8821146-14	1996	There was, however, a significant reduction in thumb red cell flux (ANOVA, P = 0.0001), reaching a maximum reduction of 33% with 4 mumol min-1 L-NMMA.	N-methylmalonamic acid	145-149	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
8553333-2	1996	The maximal work load obtained during graded bicycle ergometer exercise and the VO2 max were reduced by 16 +/- 3 W (mean +/- SE) and 3 +/- 1 ml x kg-1 x min-1 on doxazosin (p < 0.001 for both), and the running time on 5000 m track increased by 43 +/- 12 sec (p < 0.05).	Doxazosin	162-171	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
8739285-8	1996	In contrast, with enalapril treatment PAH clearance after ACTZ tended to rise (29 +/- 12 ml/ min/1.73 m2, p = 0.07).	Enalapril	18-27	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8734244-2	1996	The kalaemia which was 3.9 mmol.L-1 at admission in the intensive care unit decreased to 1.3 mmol.L-1 during a perfusion of noradrenaline (0.3 micrograms.kg-1.min-1).	Norepinephrine	124-137	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
8746189-2	1996	The Michaelis constant and maximum reaction rate of the urease were estimated as 2.14 mM and 27.18 kHz min-1, respectively, at pH 7.0 and 25.0 degrees C. Influences of pH, temperature and effectors on the response properties of the SAW urea sensor were investigated.	Urea	56-60	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
9075580-3	1996	We have used site directed mutagenesis to explore three aspects of the structure of CD59: 1) the role of the disulfide bridges in expression and function of the molecule; 2) the location of epitopes reacting with monoclonal antibodies to the molecule; and 3) the parts of the molecule that are critical to its function in inhibiting complement lysis.	Disulfides	109-118	CD59 molecule (CD59 blood group)	Homo sapiens	84-88
8877013-7	1996	According to our previously reported pilot study, we chose a cut-off value of 12 pmol 32P incorporated min-1 mg-1 protein, corresponding to the median value.	Phosphorus-32	86-89	CD59 molecule (CD59 blood group)	Homo sapiens	103-113
8867774-3	1996	Submaximal dynamic exercise and isoprenaline caused the heart rate to rise to 90-114 beats min-1, and increased the ballistocardiographic amplitude threefold, while at the same time shortening the interval between the R-wave of the electrocardiogram and the peak of the ballistocardiographic waveform (P < 0.01).	Isoproterenol	32-44	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
8867774-4	1996	In contrast, atropine accelerated the heart rate to 96 beats min-1, but did not significantly change the amplitude or temporal pattern of the ballistocardiogram.	Atropine	13-21	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
8720607-9	1996	Hepatic glucose production at 1 mU.kg body weight-1.min-1 insulin-infusion rate was significantly higher in patients than in control subjects.	Glucose	8-15	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
8682153-4	1996	Upon infusion of GSH at a constant rate of 1 mumol min-1 kg-1, GSH in plasma reached a new plateau.	Glutathione	17-20	CD59 molecule (CD59 blood group)	Homo sapiens	51-61
8682153-4	1996	Upon infusion of GSH at a constant rate of 1 mumol min-1 kg-1, GSH in plasma reached a new plateau.	Glutathione	63-66	CD59 molecule (CD59 blood group)	Homo sapiens	51-61
8803519-7	1996	Heart rate increased from 67.4 to 70.9 beats.min-1 after nitroglycerin and from 58.9 to 69.4 beats.min-1 after nifedipine.	Nitroglycerin	57-70	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
8803519-7	1996	Heart rate increased from 67.4 to 70.9 beats.min-1 after nitroglycerin and from 58.9 to 69.4 beats.min-1 after nifedipine.	Nifedipine	111-121	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
8857076-5	1996	The rate of salbutamol sulphation (pmol center dot min-1 center dot mg-1) was greater in non-smokers (27.7) than in smokers (21.3), whereas it was similar in smoker and ex-smokers (22.8).	Albuterol	12-22	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
8911881-10	1996	Based on simulation, our model predicted that a continuous infusion of 2.0 micrograms.min-1 (highest rate examined) would increase heart rate to 113 beats.min-1 at steady state and lower the plasma potassium concentration to 2.77 mmol.1(-1) 1.5 h after beginning the infusion.	Potassium	198-207	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
8925828-9	1996	At subthreshold levels of carbon dioxide, mean ventilation changed significantly from 6.3(1.1) 1.min-1 at normal temperatures to 10.8 (1.9) 1.min-1 at elevated temperatures.	Carbon Dioxide	26-40	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
8925828-9	1996	At subthreshold levels of carbon dioxide, mean ventilation changed significantly from 6.3(1.1) 1.min-1 at normal temperatures to 10.8 (1.9) 1.min-1 at elevated temperatures.	Carbon Dioxide	26-40	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
8925828-10	1996	Heart rates also increased significantly with temperature, changing from a mean of 66 (4) beats.min-1 to 102 (3) beats.min-1 at threshold levels of carbon dioxide.	Carbon Dioxide	148-162	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
8925828-10	1996	Heart rates also increased significantly with temperature, changing from a mean of 66 (4) beats.min-1 to 102 (3) beats.min-1 at threshold levels of carbon dioxide.	Carbon Dioxide	148-162	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
8925828-11	1996	The mean rates of rise of carbon dioxide partial pressure during rebreathing were significantly increased with temperature as well, changing from 0.075 (0.008) Torr.min-1 to 0.089 (0.004) Torr.min-1.	Carbon Dioxide	26-40	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
8925828-11	1996	The mean rates of rise of carbon dioxide partial pressure during rebreathing were significantly increased with temperature as well, changing from 0.075 (0.008) Torr.min-1 to 0.089 (0.004) Torr.min-1.	Carbon Dioxide	26-40	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
8954321-4	1996	Phosphatidyl inositol-phospholipase C treatment diminished or abolished cell surface expression of DAF and HRF20 on BAEC.	Phosphatidylinositols	0-21	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
8857434-5	1996	INTERVENTIONS: The effect of dobutamine infusion (6 mu g kg-1 min-1) on systemic and regional oxygen transport was studied in ten patients, with six patients serving as controls.	Dobutamine	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8857434-5	1996	INTERVENTIONS: The effect of dobutamine infusion (6 mu g kg-1 min-1) on systemic and regional oxygen transport was studied in ten patients, with six patients serving as controls.	Oxygen	94-100	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8857434-8	1996	Dobutamine increased cardiac output (3.2 +/- 0.6 vs 4.4 +/- 0.7 l x min-1 x min-2; P <0.05), splanchnic blood flow (0.68 +/- 0.28 vs 0.91 +/- 0.28 l x min-1 x m-2; p <0.05) and femoral blood flow (0.25 +/- 0.08 vs 0.32 +/- 0.11 l x min-1 x m-2; p <0.05).	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
8857434-8	1996	Dobutamine increased cardiac output (3.2 +/- 0.6 vs 4.4 +/- 0.7 l x min-1 x min-2; P <0.05), splanchnic blood flow (0.68 +/- 0.28 vs 0.91 +/- 0.28 l x min-1 x m-2; p <0.05) and femoral blood flow (0.25 +/- 0.08 vs 0.32 +/- 0.11 l x min-1 x m-2; p <0.05).	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
8857434-8	1996	Dobutamine increased cardiac output (3.2 +/- 0.6 vs 4.4 +/- 0.7 l x min-1 x min-2; P <0.05), splanchnic blood flow (0.68 +/- 0.28 vs 0.91 +/- 0.28 l x min-1 x m-2; p <0.05) and femoral blood flow (0.25 +/- 0.08 vs 0.32 +/- 0.11 l x min-1 x m-2; p <0.05).	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
8857434-8	1996	Dobutamine increased cardiac output (3.2 +/- 0.6 vs 4.4 +/- 0.7 l x min-1 x min-2; P <0.05), splanchnic blood flow (0.68 +/- 0.28 vs 0.91 +/- 0.28 l x min-1 x m-2; p <0.05) and femoral blood flow (0.25 +/- 0.08 vs 0.32 +/- 0.11 l x min-1 x m-2; p <0.05).	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
8857434-11	1996	Systemic oxygen consumption increased in response to dobutamine (141 +/- 11 vs 149 +/- 11 ml x min-1 x m-2; P <0.05) but did not change in the control group.	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
8857434-11	1996	Systemic oxygen consumption increased in response to dobutamine (141 +/- 11 vs 149 +/- 11 ml x min-1 x m-2; P <0.05) but did not change in the control group.	Dobutamine	53-63	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
8911881-10	1996	Based on simulation, our model predicted that a continuous infusion of 2.0 micrograms.min-1 (highest rate examined) would increase heart rate to 113 beats.min-1 at steady state and lower the plasma potassium concentration to 2.77 mmol.1(-1) 1.5 h after beginning the infusion.	Potassium	198-207	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
8719187-8	1996	Throughout the rest of the surgery, more propofol was used in group 1 (77 +/- 14 micrograms/kg-1/min-1) than in group 2 (42 +/- 14 micrograms/kg-1/min-1).	Propofol	41-49	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
8569195-3	1996	Levels of cell membrane CD59 were found to regulate the differential sensitivity of melanoma cells investigated to homologous C-mediated lysis; in fact, an inverse correlation (r > 0.7, p < 0.05) was found between levels of cell membrane CD59, but not of CD46 and CD55, and extent of C-mediated lysis of melanoma cells sensitized with scalar concentrations of the anti-GD3 ganglioside mAb R24.	Gangliosides	379-390	CD59 molecule (CD59 blood group)	Homo sapiens	24-28
8569195-5	1996	CD59 is bound to melanoma cells by a glycosylphosphatidylinositol anchor: treatment of C-resistant melanoma cells Mel 97, by increasing doses of phosphatidylinositol-specific phospholipase C (PI-PLC), progressively decreased cell-surface expression of CD59 and increased C-mediated lysis of cells sensitized with mAb R24.	Glycosylphosphatidylinositols	37-65	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
9284567-4	1996	SI (first study) varied from 0.82 to 8.48 x 10(-4) min-1/microU.mL (4.43 +/- 2.85 x 10(-4) min-1/microU.mL mean +/- SD) and highly correlated with SI (second study) (r = 0.89; p = 0.0002).	Silicon	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
9284567-4	1996	SI (first study) varied from 0.82 to 8.48 x 10(-4) min-1/microU.mL (4.43 +/- 2.85 x 10(-4) min-1/microU.mL mean +/- SD) and highly correlated with SI (second study) (r = 0.89; p = 0.0002).	Silicon	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
8887350-7	1996	The results indicate that NM-01 can induce complement activation because of the ratios of CD55 and CD59 to gp120 molecules on HIV virions.	nm-01	26-31	CD59 molecule (CD59 blood group)	Homo sapiens	99-103
9238658-2	1996	Both the CD55 and CD59 glycosyl phosphatidylinositol (GPI)-anchored proteins were expressed by the plasma membrane and zona pellucida of oocytes, early embryos and expanded preimplantation blastocysts; in contrast, CD46 was expressed only on the plasma membrane.	Glycosylphosphatidylinositols	23-52	CD59 molecule (CD59 blood group)	Homo sapiens	18-22
9238658-2	1996	Both the CD55 and CD59 glycosyl phosphatidylinositol (GPI)-anchored proteins were expressed by the plasma membrane and zona pellucida of oocytes, early embryos and expanded preimplantation blastocysts; in contrast, CD46 was expressed only on the plasma membrane.	Glycosylphosphatidylinositols	54-57	CD59 molecule (CD59 blood group)	Homo sapiens	18-22
8979280-5	1996	RESULTS: After 36 months of follow-up, the dapiprazole-treated group showed a significant increase in total outflow facility (C, from 0.17 +/- 0.04 to 0.22 +/- 0.07 ml min-1 mm Hg-1; p = 0.010, paired t test) and Po/C ratio (Q) significantly decreased from 113.39 +/- 31.02 to 89.22 +/- 51.66 (p = 0.036, paired t test).	dapiprazole	43-54	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
8717145-6	1996	The mean maximal dobutamine dose was 41,4 +/- 10 mu g/kg center dot min(-1).	Dobutamine	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
8575453-23	1995	The specific activity with reduced methyl viologen as the electron donor was 0.55 mumol min-1 mg-1 corresponding to a catalytic number of 1.6 s-1.	Paraquat	35-50	CD59 molecule (CD59 blood group)	Homo sapiens	88-98
7495813-3	1995	All hairpin variants cleaved with rate constants of approximately 0.3 min-1 at pH 7.5 in 10 nM MgCl2 at 25 degrees C, regardless of the length or sequence of the intermolecular helices.	Magnesium Chloride	95-100	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
7503062-4	1995	The mean current creatinine clearance was 88.5 +/- 21.2 mL/min/1.73 m2, which is 92.9% of that in healthy age- and sex-matched controls with two kidneys.	Creatinine	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
8787473-6	1995	RESULTS: Results showed an increase of approximately 31% in the percent disappearance rate of indocyanine green with the addition of low-dose dopamine (4 micrograms.kg-1.min-1) (p < 0.01).	Indocyanine Green	94-111	CD59 molecule (CD59 blood group)	Homo sapiens	170-175
8787473-6	1995	RESULTS: Results showed an increase of approximately 31% in the percent disappearance rate of indocyanine green with the addition of low-dose dopamine (4 micrograms.kg-1.min-1) (p < 0.01).	Dopamine	142-150	CD59 molecule (CD59 blood group)	Homo sapiens	170-175
8703663-9	1995	During bicycle exercise, the increase in HR was significantly greater after rilmenidine (+50 vs 41 beats min-1, P = 0.04).	Rilmenidine	76-87	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
8750221-6	1995	Glucose production was lower (1.7 +/- 0.4 vs 0.5 +/- 0.4 mg kg-1 min-1, p < 0.05), and utilization was similar at the end of the matched-insulinaemia IV and IP clamps, respectively.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
8599674-1	1995	For hydrated metmyoglobin, methemoglobin, and lysozyme powders, the freezable water fraction of between approximately 0.3-0.4 g water/g protein up to approximately 0.7-0.8 g water/g protein has been fully vitrified by cooling at rates up to approximately 1500 K min-1 and the influence of cooling rate characterized by x-ray diffractograms.	Water	78-83	CD59 molecule (CD59 blood group)	Homo sapiens	262-267
8599674-3	1995	Measurements by differential scanning calorimetry have shown that this vitreous but freezable water fraction undergoes, on reheating at a rate of 30 K min-1, a glass-->liquid transition with an onset temperature of between approximately 164 and approximately 174 K, with a width of between approximately 9 and approximately 16 degrees and an increase in heat capacity of between approximately 20 and approximately 40 J K-1 (mol of freezable water)-1 but that the glass transition disappears upon crystallization of the freezable water.	Water	94-99	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
8536377-7	1995	Removal of CD59 from the cell surface by phosphatidylinositol-specific phospholipase C (PI-PLC) demonstrated its production as a glycosyl phosphatidylinositol (GPI)-anchored protein.	Glycosylphosphatidylinositols	129-158	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
8536377-7	1995	Removal of CD59 from the cell surface by phosphatidylinositol-specific phospholipase C (PI-PLC) demonstrated its production as a glycosyl phosphatidylinositol (GPI)-anchored protein.	Glycosylphosphatidylinositols	160-163	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
8593924-6	1995	Glucose metabolic clearance in the fasting state was 3.68 +2- 0.21 mg kg-1 min-1 before and 2.46 +/- 0.09 (n = 2.44 to 3.46 ml kg-1 min-1) after surgery.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
8593924-6	1995	Glucose metabolic clearance in the fasting state was 3.68 +2- 0.21 mg kg-1 min-1 before and 2.46 +/- 0.09 (n = 2.44 to 3.46 ml kg-1 min-1) after surgery.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
8750221-7	1995	By contrast, glucose production was higher (1.7 +/- 0.5 IV vs 2.7 +/- 0.3 IP mg kg-1 min-1, p < 0.01) and glucose utilization lower (4.4 +/- 1.0 IV vs 3.3 +/- 0.2 IP mg kg-1 min-1, p < 0.05) with IP delivery at the end of the matched-dose clamps.	Glucose	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
8750221-7	1995	By contrast, glucose production was higher (1.7 +/- 0.5 IV vs 2.7 +/- 0.3 IP mg kg-1 min-1, p < 0.01) and glucose utilization lower (4.4 +/- 1.0 IV vs 3.3 +/- 0.2 IP mg kg-1 min-1, p < 0.05) with IP delivery at the end of the matched-dose clamps.	Glucose	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
7591134-2	1995	Following fractionation of the leukocytes, much higher levels of chitinase activity were detected in granulocyte-rich homogenates (approximately 7.2 nmol of GlcNAc released min-1 mg of protein-1) than in lymphocyte- and monocyte-rich homogenates (approximately 0.22 and 0.26 nmol of GlcNAc released min-1 mg of protein-1, respectively).	Acetylglucosamine	157-163	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
7591134-3	1995	Low levels of chitinase activity were detected in human serum (approximately 4 pmol of GlcNAc released min-1 mg of protein-1).	Acetylglucosamine	87-93	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
8719980-4	1995	The patients with abnormal 123I-BMIPP images terminated exercise after a shorter period (4.5 +/- 2.6 vs 6.7 +/- 4.1 min; P < 0.01) and at a lower rate pressure product (16,124 +/- 5211 vs 20,246 +/- 6564 mmHg x beats min-1; P < 0.01) than those with normal 123I-BMIPP images.	iodofiltic acid	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
8833982-5	1995	GG167 is "heart-cut" to a Spherisorb-SCX column (5 microns, 100 mm x 4.6 mm) and eluted with 35 mM phosphate buffer (pH 2.5):acetonitrile (50:50, v/v) at 1.5 ml min-1 for final separation.	Zanamivir	0-5	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
8746633-9	1995	In the presence of glycosaminoglycans, the maximal thrombin inhibition rate (k2 x 10(-3) M-1 min-1) for rHCII was 10.4 +/- 2.5 at 100 micrograms/ml heparin and 16.0 +/- 4.3 at 1000 micrograms/ml dermatan sulfate compared to 9.0 +/- 0.7 at 200 micrograms/ml heparin and 18.5 +/- 5.3 at 1000 micrograms/ml dermatan sulfate for pHCII.	Glycosaminoglycans	19-37	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8746633-9	1995	In the presence of glycosaminoglycans, the maximal thrombin inhibition rate (k2 x 10(-3) M-1 min-1) for rHCII was 10.4 +/- 2.5 at 100 micrograms/ml heparin and 16.0 +/- 4.3 at 1000 micrograms/ml dermatan sulfate compared to 9.0 +/- 0.7 at 200 micrograms/ml heparin and 18.5 +/- 5.3 at 1000 micrograms/ml dermatan sulfate for pHCII.	Heparin	148-155	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8746633-9	1995	In the presence of glycosaminoglycans, the maximal thrombin inhibition rate (k2 x 10(-3) M-1 min-1) for rHCII was 10.4 +/- 2.5 at 100 micrograms/ml heparin and 16.0 +/- 4.3 at 1000 micrograms/ml dermatan sulfate compared to 9.0 +/- 0.7 at 200 micrograms/ml heparin and 18.5 +/- 5.3 at 1000 micrograms/ml dermatan sulfate for pHCII.	Dermatan Sulfate	195-211	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8746633-9	1995	In the presence of glycosaminoglycans, the maximal thrombin inhibition rate (k2 x 10(-3) M-1 min-1) for rHCII was 10.4 +/- 2.5 at 100 micrograms/ml heparin and 16.0 +/- 4.3 at 1000 micrograms/ml dermatan sulfate compared to 9.0 +/- 0.7 at 200 micrograms/ml heparin and 18.5 +/- 5.3 at 1000 micrograms/ml dermatan sulfate for pHCII.	Heparin	257-264	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8746633-9	1995	In the presence of glycosaminoglycans, the maximal thrombin inhibition rate (k2 x 10(-3) M-1 min-1) for rHCII was 10.4 +/- 2.5 at 100 micrograms/ml heparin and 16.0 +/- 4.3 at 1000 micrograms/ml dermatan sulfate compared to 9.0 +/- 0.7 at 200 micrograms/ml heparin and 18.5 +/- 5.3 at 1000 micrograms/ml dermatan sulfate for pHCII.	Dermatan Sulfate	304-320	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8521960-1	1995	We have observed that the extracellular domain of T beta RI and protectin (CD59), an inhibitor of the membrane attack complex of complement, share structural features, a distinct spacing of ten cysteines and a C-terminal "Cys-box".	Cysteine	194-203	CD59 molecule (CD59 blood group)	Homo sapiens	75-79
8521960-1	1995	We have observed that the extracellular domain of T beta RI and protectin (CD59), an inhibitor of the membrane attack complex of complement, share structural features, a distinct spacing of ten cysteines and a C-terminal "Cys-box".	Cysteine	222-225	CD59 molecule (CD59 blood group)	Homo sapiens	75-79
8619329-8	1995	Theophylline, at a dose lacking effects on myocardial work, markedly attenuated the coronary flow response to exogenous adenosine, and decreased CS flow to 89 (58-119), 120 (79-161) and 190 (162-218) mL min-1 at normoxic rest, hypoxic rest and hypoxic exercise, respectively.	Theophylline	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
8583409-5	1995	During exercise ammonia was released in gradually increasing amounts and plateaued after 1 h exercise at a rate of approximately 80 mumol min-1.	Ammonia	16-23	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
8881871-5	1995	Left ventricular pressure was recorded at rest and 5 min after a 4 min infusion of dipyridamole (0.14 mg.kg-1.min-1).	Dipyridamole	83-95	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
7502993-5	1995	Chlorine uptake in a 33-mm diameter sampler with a 10.8-mm path length was found to be essentially independent of wind direction and varied by approximately 23% for wind speeds ranging from 5.1 to 203 cm s-1 (10-400 ft min-1).	Chlorine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
7491948-5	1995	At an average plasma concentration of beta-hydroxybutyrate of 0.043 mumol/ml, the utilization rate was estimated to be 0.48 nmol.ml-1.min-1.	3-Hydroxybutyric Acid	38-58	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
8678249-3	1995	In addition, all the patients were given a continuous infusion of mivacurium 10 micrograms.kg-1 min-1 after tracheal intubation which was adjusted to maintain 90% depression of T1.	Mivacurium	66-76	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
8703646-5	1995	Three hours after its administration and before LBNP, losartan selectively increased renal blood flow (PAH clearance) by 8.3% (3.5 to 13.1%, 95% CI) from 1.25 +/- 0.08 l min-1 (P < 0.05) and decreased plasma aldosterone levels by 58% (29 to 87%, 95% CI) from 22 +/- 3 ng 100 ml-1 (P < 0.05).	Losartan	54-62	CD59 molecule (CD59 blood group)	Homo sapiens	170-175
8703648-12	1995	Both noradrenaline and methoxamine produced dose-dependent venoconstriction: the geometric mean ED50 for noradrenaline was 4.41 ng min-1 and for methoxamine was 2558 ng min-1; the potency ratio (noradrenaline/methoxamine) was 2884.	Norepinephrine	5-18	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8703648-12	1995	Both noradrenaline and methoxamine produced dose-dependent venoconstriction: the geometric mean ED50 for noradrenaline was 4.41 ng min-1 and for methoxamine was 2558 ng min-1; the potency ratio (noradrenaline/methoxamine) was 2884.	Norepinephrine	5-18	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
8703648-12	1995	Both noradrenaline and methoxamine produced dose-dependent venoconstriction: the geometric mean ED50 for noradrenaline was 4.41 ng min-1 and for methoxamine was 2558 ng min-1; the potency ratio (noradrenaline/methoxamine) was 2884.	Methoxamine	23-34	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8703648-12	1995	Both noradrenaline and methoxamine produced dose-dependent venoconstriction: the geometric mean ED50 for noradrenaline was 4.41 ng min-1 and for methoxamine was 2558 ng min-1; the potency ratio (noradrenaline/methoxamine) was 2884.	Methoxamine	23-34	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
8703648-12	1995	Both noradrenaline and methoxamine produced dose-dependent venoconstriction: the geometric mean ED50 for noradrenaline was 4.41 ng min-1 and for methoxamine was 2558 ng min-1; the potency ratio (noradrenaline/methoxamine) was 2884.	Norepinephrine	105-118	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8703648-12	1995	Both noradrenaline and methoxamine produced dose-dependent venoconstriction: the geometric mean ED50 for noradrenaline was 4.41 ng min-1 and for methoxamine was 2558 ng min-1; the potency ratio (noradrenaline/methoxamine) was 2884.	Methoxamine	145-156	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
8703648-12	1995	Both noradrenaline and methoxamine produced dose-dependent venoconstriction: the geometric mean ED50 for noradrenaline was 4.41 ng min-1 and for methoxamine was 2558 ng min-1; the potency ratio (noradrenaline/methoxamine) was 2884.	Norepinephrine	105-118	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8703648-12	1995	Both noradrenaline and methoxamine produced dose-dependent venoconstriction: the geometric mean ED50 for noradrenaline was 4.41 ng min-1 and for methoxamine was 2558 ng min-1; the potency ratio (noradrenaline/methoxamine) was 2884.	Methoxamine	145-156	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
8703649-6	1995	infused propranolol (0.1 mu kg-1 min-1) was determined during normoxaemia and hypoxaemia (peripheral oxygen saturation; SpO2 80%), and compared with the contra-lateral (control) arm.	Propranolol	8-19	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
8582132-8	1995	Infusion of GH at 12 mU kg-1 min-1 induced a less pronounced insulin resistance both with regards to maximal effect (glucose infusion rate C - GH 1.4 +/- 0.5 mg kg-1 min-1, p < 0.05) and duration (3 h).	Glucose	117-124	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
8881872-6	1995	RESULTS: Dobutamine increased heart rate (rest = 69 +/- 9 vs dobutamine = 138 +/- 13 beats.min-1; P < 0.01), whereas systolic blood pressure did not change significantly (rest = 136 +/- 15 vs dobutamine = 150 +/- 25 mmHg, P = ns).	Dobutamine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
8588954-6	1995	The transport systems obeyed Michaelis-Menten kinetics, with the kinetic parameters of the glucose transport system (Km = 2.5mM, Vmax = 7.7 nmol min-1 mg-1 protein) suggesting a higher proportion of PT cells originating from the S1-S2 segment of the nephron.	Glucose	91-98	CD59 molecule (CD59 blood group)	Homo sapiens	145-155
7593188-0	1995	Exogenous glycosyl phosphatidylinositol-anchored CD59 associates with kinases in membrane clusters on U937 cells and becomes Ca(2+)-signaling competent.	Glycosylphosphatidylinositols	10-39	CD59 molecule (CD59 blood group)	Homo sapiens	49-53
7593188-1	1995	CD59, an 18-20-kD complement inhibitor anchored to the membrane via glycosyl phosphatidylinositol (GPI), can induce activation of T cells and neutrophils upon cross-linking with antibody.	Glycosylphosphatidylinositols	68-97	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
7593188-1	1995	CD59, an 18-20-kD complement inhibitor anchored to the membrane via glycosyl phosphatidylinositol (GPI), can induce activation of T cells and neutrophils upon cross-linking with antibody.	Glycosylphosphatidylinositols	99-102	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
7593188-5	1995	Confocal microscopy revealed an initial diffuse distribution of CD59 that became clustered within 2 h to give a pattern similar to endogenous GPI-anchored molecules.	Glycosylphosphatidylinositols	142-145	CD59 molecule (CD59 blood group)	Homo sapiens	64-68
7593188-7	1995	Newly incorporated CD59 did not deliver a Ca2+ signal upon cross-linking, but at a time when it had become clustered and associated with kinase activity, cross-linking induced a large calcium transient, indicating that CD59 had incorporated in a specialized microenvironment that allowed it to function fully as a signal-transducing molecule.	Calcium	184-191	CD59 molecule (CD59 blood group)	Homo sapiens	19-23
7593645-6	1995	In the basal postabsorptive state, there was small but significant net output of glucose by the kidney (66 +/- 22 mumol.min-1, P = 0.016).	Glucose	81-88	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
7593645-7	1995	However, since renal glucose fractional extraction averaged 2.9 +/- 0.3%, there was considerable renal glucose uptake (2.3 +/- 0.2 mumol.kg-1.min-1) which accounted for 20.2 +/- 1.7% of systemic glucose disposal (11.4 +/- 0.5 mumol.kg-1.min-1).	Glucose	103-110	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
7593645-7	1995	However, since renal glucose fractional extraction averaged 2.9 +/- 0.3%, there was considerable renal glucose uptake (2.3 +/- 0.2 mumol.kg-1.min-1) which accounted for 20.2 +/- 1.7% of systemic glucose disposal (11.4 +/- 0.5 mumol.kg-1.min-1).	Glucose	103-110	CD59 molecule (CD59 blood group)	Homo sapiens	237-242
7593645-7	1995	However, since renal glucose fractional extraction averaged 2.9 +/- 0.3%, there was considerable renal glucose uptake (2.3 +/- 0.2 mumol.kg-1.min-1) which accounted for 20.2 +/- 1.7% of systemic glucose disposal (11.4 +/- 0.5 mumol.kg-1.min-1).	Glucose	103-110	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
7593645-7	1995	However, since renal glucose fractional extraction averaged 2.9 +/- 0.3%, there was considerable renal glucose uptake (2.3 +/- 0.2 mumol.kg-1.min-1) which accounted for 20.2 +/- 1.7% of systemic glucose disposal (11.4 +/- 0.5 mumol.kg-1.min-1).	Glucose	103-110	CD59 molecule (CD59 blood group)	Homo sapiens	237-242
7593645-8	1995	Renal glucose release (3.2 +/- 0.2 mumol.kg-1.min-1) accounted for 27.8 +/- 2.1% of systemic glucose appearance (11.4 +/- 0.5 mumol.kg-1.min-1).	Glucose	6-13	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
7593645-8	1995	Renal glucose release (3.2 +/- 0.2 mumol.kg-1.min-1) accounted for 27.8 +/- 2.1% of systemic glucose appearance (11.4 +/- 0.5 mumol.kg-1.min-1).	Glucose	6-13	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
7593645-9	1995	Epinephrine infusion, which increased plasma epinephrine to levels observed during hypoglycemia (3722 +/- 453 pmol/liter) increased renal glucose release nearly twofold (5.2 +/- 0.5 vs 2.8 +/- 0.1 mol.kg-1.min-1, P = 0.01) so that at the end of the infusion, renal glucose release accounted for 40.3 +/- 5.5% of systemic glucose appearance and essentially all of the increase in systemic glucose appearance.	Epinephrine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
7594566-4	1995	Cell surface expression of the CD and DC chimeric proteins was detected with DAF- and CD59-specific antisera.	Cadmium	31-33	CD59 molecule (CD59 blood group)	Homo sapiens	86-90
7593188-7	1995	Newly incorporated CD59 did not deliver a Ca2+ signal upon cross-linking, but at a time when it had become clustered and associated with kinase activity, cross-linking induced a large calcium transient, indicating that CD59 had incorporated in a specialized microenvironment that allowed it to function fully as a signal-transducing molecule.	Calcium	184-191	CD59 molecule (CD59 blood group)	Homo sapiens	219-223
7472585-8	1995	After propranolol treatment, Kmono decreased (0.082 +/- 0.014 min-1) but remained significantly higher in eight patients than normal subject levels (p < 0.05), while the rate pressure product decreased significantly (7500 +/- 1700) toward the normal range (7900 +/- 1500).	Propranolol	6-17	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
7472585-8	1995	After propranolol treatment, Kmono decreased (0.082 +/- 0.014 min-1) but remained significantly higher in eight patients than normal subject levels (p < 0.05), while the rate pressure product decreased significantly (7500 +/- 1700) toward the normal range (7900 +/- 1500).	kmono	29-34	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8708993-5	1995	The mean renal clearance of frusemide was 90.2 +/- 16.9 mL min-1 during the first period and 91.5 +/- 29.3 mL min-1 in the remaining period, during which the stimulation of urine production was absent.	Furosemide	28-37	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
8708993-6	1995	The renal clearance of the acyl glucuronide was 702 +/- 221 mL min-1 in the first period, but only 109 +/- 51.0 mL min-1 in the second period.	acyl glucuronide	27-43	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
7481554-0	1995	Down-regulation of CD59 (protectin) expression on human colorectal adenocarcinoma cell lines by levamisole.	Levamisole	96-106	CD59 molecule (CD59 blood group)	Homo sapiens	19-23
7594597-7	1995	Treatment of virus with phosphatidylinositol-specific phospholipase C (PI-PLC), which removes glycosylphosphatidylinositol-anchored CD55 and CD59, increased the sensitivity of HTLV-I to C-mediated destruction in the presence of anti-HTLV-I Abs.	Phosphatidylinositols	24-44	CD59 molecule (CD59 blood group)	Homo sapiens	141-145
7553895-1	1995	CD55 and CD59 are both glycosylphosphatidylinositol (GPI)-anchored complement regulatory proteins found on the surface of most hemopoietic cells.	Glycosylphosphatidylinositols	23-51	CD59 molecule (CD59 blood group)	Homo sapiens	9-13
7553895-5	1995	Treatment with phosphatidylinositol-specific phospholipase C released both the CD55 and CD59 antigens from the surface of CD56+CD3- cells, indicating that both are GPI-anchored, as they are on other lymphocytes.	Phosphatidylinositols	15-35	CD59 molecule (CD59 blood group)	Homo sapiens	88-92
7553895-5	1995	Treatment with phosphatidylinositol-specific phospholipase C released both the CD55 and CD59 antigens from the surface of CD56+CD3- cells, indicating that both are GPI-anchored, as they are on other lymphocytes.	Glycosylphosphatidylinositols	164-167	CD59 molecule (CD59 blood group)	Homo sapiens	88-92
7553895-1	1995	CD55 and CD59 are both glycosylphosphatidylinositol (GPI)-anchored complement regulatory proteins found on the surface of most hemopoietic cells.	Glycosylphosphatidylinositols	53-56	CD59 molecule (CD59 blood group)	Homo sapiens	9-13
7559509-7	1995	In the prothrombinase complex, PN-2/A beta PP inhibited factor Xa with a kassoc = 1.8 +/- 0.7 x 10(6) M-1 min-1 similar to antithrombin III and heparin inhibition (kassoc of 3.0 +/- 0.2 x 10(6) M-1 min-1).	beta pp	38-45	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
7559509-7	1995	In the prothrombinase complex, PN-2/A beta PP inhibited factor Xa with a kassoc = 1.8 +/- 0.7 x 10(6) M-1 min-1 similar to antithrombin III and heparin inhibition (kassoc of 3.0 +/- 0.2 x 10(6) M-1 min-1).	beta pp	38-45	CD59 molecule (CD59 blood group)	Homo sapiens	198-203
7572705-6	1995	Each subject was studied in the basal state and during a 1-h infusion of epinephrine (0.015 microgram kg(-1 min(-1) after 84 h of total energy restriction and after 84 h of carbohydrate restriction (12 h after the final lipid infusion).	Epinephrine	73-84	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
7485491-4	1995	Throughout the first period they received a continuous infusion of glucose (2 mg.kg-1.min-1) and amino acids.	Glucose	67-74	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
7485491-5	1995	During the second period, in addition to the glucose, they received a continuous infusion of 1 mg.kg-1.min-1 of long-chain triglycerides emulsion.	Triglycerides	123-136	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
7574946-3	1995	Dobutamine infusion was started at a rate of 5 micrograms.kg-1.min-2 and increased to 10 and 20 micrograms.kg-1.min-2 at 15-minute intervals.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
7574714-4	1995	However, kcat increased from 1.5 min-1 for the 8-membered cyclic peptide to 148 min-1 for the 14-membered cyclic peptide.	Peptides, Cyclic	58-72	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
7574714-4	1995	However, kcat increased from 1.5 min-1 for the 8-membered cyclic peptide to 148 min-1 for the 14-membered cyclic peptide.	Peptides, Cyclic	58-72	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
7574714-4	1995	However, kcat increased from 1.5 min-1 for the 8-membered cyclic peptide to 148 min-1 for the 14-membered cyclic peptide.	Peptides, Cyclic	106-120	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
7574714-4	1995	However, kcat increased from 1.5 min-1 for the 8-membered cyclic peptide to 148 min-1 for the 14-membered cyclic peptide.	Peptides, Cyclic	106-120	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
7574714-7	1995	With thermolysin, kcat increased from 7 min-1 for the 10-membered cyclic peptide to 27,000 min-1 for the 14-membered cyclic peptide.	Peptides, Cyclic	66-80	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
7574714-7	1995	With thermolysin, kcat increased from 7 min-1 for the 10-membered cyclic peptide to 27,000 min-1 for the 14-membered cyclic peptide.	Peptides, Cyclic	66-80	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
7574714-7	1995	With thermolysin, kcat increased from 7 min-1 for the 10-membered cyclic peptide to 27,000 min-1 for the 14-membered cyclic peptide.	Peptides, Cyclic	117-131	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
7574714-7	1995	With thermolysin, kcat increased from 7 min-1 for the 10-membered cyclic peptide to 27,000 min-1 for the 14-membered cyclic peptide.	Peptides, Cyclic	117-131	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
7545473-5	1995	AET-treated RBCs showed an increase in C9 binding and an increased C9/C7 ratio consistent with functional loss of CD59/membrane inhibitor of reactive lysis (MIRL).	2-(2-Aminoethyl)isothiourea dihydrobromide	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	114-118
7545473-5	1995	AET-treated RBCs showed an increase in C9 binding and an increased C9/C7 ratio consistent with functional loss of CD59/membrane inhibitor of reactive lysis (MIRL).	2-(2-Aminoethyl)isothiourea dihydrobromide	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	119-155
7545473-5	1995	AET-treated RBCs showed an increase in C9 binding and an increased C9/C7 ratio consistent with functional loss of CD59/membrane inhibitor of reactive lysis (MIRL).	2-(2-Aminoethyl)isothiourea dihydrobromide	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	157-161
7545473-6	1995	In contrast, calcium-loaded RBCs had minimally increased C9 binding that resulted in C9/C7 ratios that were less than those for untreated RBCs, suggesting that CD59/MIRL inactivation had not occurred.	Calcium	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	165-169
7547240-5	1995	DTD activity was highest in non-small-cell lung (NSCLC)-tumours (mean 123 nmol DCPIP min-1 mg-1), followed by colon carcinoma (mean 75 nmol min-1 mg-1) and squamous cell carcinoma of the head and neck (6-fold lower than NSCLC).	2,6-Dichloroindophenol	79-84	CD59 molecule (CD59 blood group)	Homo sapiens	85-95
8554932-12	1995	Salbutamol caused a significant increase in heart rate compared with placebo and effects were additive to those of hypoxia at 74 +/- 2 vs 67 +/- 3 beats min-1 during normoxaemia and 84 +/- 3 vs 77 +/- 4 beats min-1 during hypoxaemia, respectively (P < 0.05).	Albuterol	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	209-214
8554933-9	1995	Salbutamol did not elicit bronchodilation in CF patients, but increased heart rate from 77 +/- 2 to 103 +/- 3 beats min-1 (P < 0.05).	Albuterol	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
8555414-7	1995	In the absence of glutathione, the rate constant for the disappearance of the ifosfamide mustard signal at 25 degrees C (pH 7) was 1.98 x 10(-3) min-1 (t1/2 = 350 min).	Ifosfamide	78-88	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
8555414-8	1995	In the presence of a 10-fold molar excess of glutathione, this rate constant was 1.95 x 10(-3) min-1 (t1/2 = 355 min), indicating that the spontaneous formation of an aziridinium ion is the rate-limiting event in the reaction with glutathione.	Glutathione	45-56	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
8555414-8	1995	In the presence of a 10-fold molar excess of glutathione, this rate constant was 1.95 x 10(-3) min-1 (t1/2 = 355 min), indicating that the spontaneous formation of an aziridinium ion is the rate-limiting event in the reaction with glutathione.	aziridinium	167-178	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
9383471-2	1995	This is a facile reaction, with an uncatalyzed rate for a typical RNA phosphoester of approximately 10(-4) min-1 in the presence of 1 mM Pb(OAc)2 at pH 7.0 and 23 degrees C. The Mg(2+)-dependent reaction is more difficult, with an uncatalyzed rate of approximately 10(-7) min-1 under comparable conditions.	pb(oac)2	137-145	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
9383471-2	1995	This is a facile reaction, with an uncatalyzed rate for a typical RNA phosphoester of approximately 10(-4) min-1 in the presence of 1 mM Pb(OAc)2 at pH 7.0 and 23 degrees C. The Mg(2+)-dependent reaction is more difficult, with an uncatalyzed rate of approximately 10(-7) min-1 under comparable conditions.	pb(oac)2	137-145	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
9383471-2	1995	This is a facile reaction, with an uncatalyzed rate for a typical RNA phosphoester of approximately 10(-4) min-1 in the presence of 1 mM Pb(OAc)2 at pH 7.0 and 23 degrees C. The Mg(2+)-dependent reaction is more difficult, with an uncatalyzed rate of approximately 10(-7) min-1 under comparable conditions.	magnesium ion	178-184	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
9383471-2	1995	This is a facile reaction, with an uncatalyzed rate for a typical RNA phosphoester of approximately 10(-4) min-1 in the presence of 1 mM Pb(OAc)2 at pH 7.0 and 23 degrees C. The Mg(2+)-dependent reaction is more difficult, with an uncatalyzed rate of approximately 10(-7) min-1 under comparable conditions.	magnesium ion	178-184	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
8555414-8	1995	In the presence of a 10-fold molar excess of glutathione, this rate constant was 1.95 x 10(-3) min-1 (t1/2 = 355 min), indicating that the spontaneous formation of an aziridinium ion is the rate-limiting event in the reaction with glutathione.	Glutathione	231-242	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
8690177-4	1995	During euglycaemic, hyperinsulinaemic clamp (2 mU x kg-1 x min-1) in combination with indirect calorimetry, a 35% (p=0.005) increase in whole-body insulin-stimulated glucose disposal rate, predominantly due to an increased non-oxidative glucose metabolism (p=0.02) was demonstrated in teh gliclazide-treated patients when compared to pre-treatment values.	Glucose	166-173	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
7490134-3	1995	These populations differed in their expression of the glycosyl-phosphatidylinositol (GPI)-anchored inhibitors CD59 and decay-accelerating factor (DAF).	Glycosylphosphatidylinositols	54-83	CD59 molecule (CD59 blood group)	Homo sapiens	110-114
8557059-5	1995	Forty and 60 ng kg-1 min-1 urodilatin showed a significant effect on the central (FEV1, PEF, MEF75) and peripheral airways (MEF50, MEF25) after 10 min infusion (P < 0.05).	Ularitide	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	21-26
8557059-6	1995	A bronchodilation not significantly different from 1.25 mg salbutamol was induced by 40 ng kg-1 min-1 in the central airways only, while 60 ng kg-1 min-1 led to a similar effect at all levels of the bronchial tree.	Albuterol	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
7490134-3	1995	These populations differed in their expression of the glycosyl-phosphatidylinositol (GPI)-anchored inhibitors CD59 and decay-accelerating factor (DAF).	Glycosylphosphatidylinositols	85-88	CD59 molecule (CD59 blood group)	Homo sapiens	110-114
7490134-9	1995	As CD48, DAF and CD59 are all GPI-anchored molecules it is likely that a defect in the GPI-anchoring mechanism is responsible for the generation of the second population of cells.	Glycosylphosphatidylinositols	30-33	CD59 molecule (CD59 blood group)	Homo sapiens	17-21
7490134-9	1995	As CD48, DAF and CD59 are all GPI-anchored molecules it is likely that a defect in the GPI-anchoring mechanism is responsible for the generation of the second population of cells.	Glycosylphosphatidylinositols	87-90	CD59 molecule (CD59 blood group)	Homo sapiens	17-21
8568663-10	1995	During the 10 min bout of exercise in the second protocol, acetylcholine was given via a brachial artery catheter at 16 micrograms min-1 for 3 min to evoke NO release from the vascular endothelium.	Acetylcholine	59-72	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8568663-14	1995	The L-NMMA was infused at 4 mg min-1 for 10 min.	omega-N-Methylarginine	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
7476281-4	1995	Twelve hours after the last bout of exercise, SI was 8.47 +/- 1.12 x 10(-5) min-1/pmol/L, as compared with 6.98 +/- 1.17 x 10(-5) min-1/pmol/L 84 hours after exercise (mean +/- SE, P = .005).	Silicon	46-48	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
8548921-5	1995	Kinetic constants for decarbamylation of human pseudocholinesterase (EC 3.1.1.8) at 30 degrees C were approximately 0.005 min-1 for dimethylcarbamates and 0.010 min-1 for monomethylcarbamates, when 1 mmol/l propionylthiocholine was used as substrate.	N-methylcarbamate	171-191	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
7661348-8	1995	Study 1: The peripheral carbon dioxide sensitivities averaged 0.50 +/- 0.08 (control) and 0.28 +/- 0.05 l.min-1.mmHg-1 (isoflurane; P < 0.01).	Isoflurane	120-130	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
7653805-6	1995	Oxygen consumption averaged 93 +/- 28 mL.min-1.m-2 in the normothermic patients and 43 +/- 10 mL.min-1.m-2 in the hypothermic group.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
7661348-10	1995	Study 2: Within 30 s of exposure to 0.1 MAC isoflurane, ventilation decreased significantly, from 17.7 +/- 1.6 (hypoxia, awake) to 15.0 +/- 1.5 l.min-1 (hypoxia, isoflurane).	Isoflurane	44-54	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
7661348-10	1995	Study 2: Within 30 s of exposure to 0.1 MAC isoflurane, ventilation decreased significantly, from 17.7 +/- 1.6 (hypoxia, awake) to 15.0 +/- 1.5 l.min-1 (hypoxia, isoflurane).	Isoflurane	162-172	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
8528569-5	1995	Local intra-arterial infusion of the NO donor, sodium nitroprusside (40 micrograms kg-1 min-1) for 10 min induced macroscopically apparent gastric mucosal injury.	Nitroprusside	47-67	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
8528569-13	1995	also reduced the mucosal injury induced by local intra-arterial infusion of the nitrosothiol, S-nitroso-N-acetyl-penicillamine (40 micrograms kg-1 min-1), but not that induced by local infusion of endothelin-1 (5 pmol kg-1 min-1), indicating specificity of action.	S-Nitroso-N-Acetylpenicillamine	94-126	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
8528569-13	1995	also reduced the mucosal injury induced by local intra-arterial infusion of the nitrosothiol, S-nitroso-N-acetyl-penicillamine (40 micrograms kg-1 min-1), but not that induced by local infusion of endothelin-1 (5 pmol kg-1 min-1), indicating specificity of action.	S-Nitroso-N-Acetylpenicillamine	94-126	CD59 molecule (CD59 blood group)	Homo sapiens	223-228
8582395-8	1995	During dobutamine infusion, exercise resulted in a further increase in heart rate from 108 +/- 11 to 122 +/- 17 mmHg (P < 0.05), in cardiac output from 7.4 +/- 0.9 to 10.3 +/- 2.5 l.min-1 (P < 0.05), and in left ventricular dP/dtmax from 2181 +/- 220 to 2620 +/- 214 mmHg.s-1 (P < 0.05).	Dobutamine	7-17	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
7652762-6	1995	Systolic right ventricular pressure was moderately raised (36 to 48 mmHg) in 5 children; mean creatinine clearance was 99 ml/min/1.73 m2.	Creatinine	94-104	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
8527284-8	1995	The mean oral clearance of alprazolam was 1.15 +/- 0.32 ml min-1 kg-1.	Alprazolam	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	59-69
7544344-6	1995	CD59 was found to specifically bind to a peptide corresponding to residues 334-385 of the human C8 alpha-subunit, and to require a disulfide bond between Cys345 and Cys369.	Disulfides	131-140	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
7652762-14	1995	Mean creatinine clearance is 101 ml/min/1.73 m2.	Creatinine	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
7645699-3	1995	The study demonstrated that not only can reliable capnographic tracings be obtained from a thin catheter placed in the unintubated airway, but the subject may also receive up to 6 l.min-1 of oxygen via the nasal route without interference with the accuracy of the measurements.	Oxygen	191-197	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
7475078-5	1995	After operation for 4 h at a flow rate of 200 ml min-1, the reduction in blood urea concentration for reactor dimensions of 2 x 10 cm, 2 x 20 cm, 4 x 10 cm and 4 x 20 cm were 38%, 52%, 60% and 62%, respectively.	Urea	79-83	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7475078-7	1995	The results for flow rates of 100, 200, 300 and 400 ml min-1 predicted blood urea reductions of 38, 60, 70 and 76%, respectively.	Urea	77-81	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
7475078-8	1995	Although, the conversion of urea in the reactor decreased from 100% to 96% for the respective flows of 100 to 400 ml min-1, the high turnover of reactor volume at a higher flow rate was responsible for the improved reduction of the patient"s blood urea level.	Urea	28-32	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
7475078-8	1995	Although, the conversion of urea in the reactor decreased from 100% to 96% for the respective flows of 100 to 400 ml min-1, the high turnover of reactor volume at a higher flow rate was responsible for the improved reduction of the patient"s blood urea level.	Urea	248-252	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
7484176-4	1995	The degree of partial restoration of HRpeak to more normal values within seconds of 60% O2 inhalation (range 5-35 beats min-1 HRpeak increase) was greatest in subjects with low HRpeak.	Oxygen	88-90	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
7645702-3	1995	Using a fresh gas flow of 2 l.min-1, the ratio of inspired isoflurane concentration to isoflurane vaporizer setting was found to be approximately 4/5th after 5 min of anaesthesia.	Isoflurane	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
7645702-3	1995	Using a fresh gas flow of 2 l.min-1, the ratio of inspired isoflurane concentration to isoflurane vaporizer setting was found to be approximately 4/5th after 5 min of anaesthesia.	Isoflurane	87-97	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
8556223-7	1995	In urine only morphine and its glucuronides are found, with renal clearance values of 214 ml.min-1 for morphine and 132 ml.min-1 for the glucuronides.	Morphine	14-22	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
7554756-9	1995	An exercise load of 50 W and a dobutamine infusion of 15 micrograms min-1 kg-1 gave the following results respectively: heart rate, 120.3 +/- 3.0 beats/min versus 110.2 +/- 3.0 beats/min; SD, 16.0 +/- 1.1 ms versus 16.3 +/- 2.5 ms; low-frequency component, 4.3 +/- 0.3 ln-ms2 versus 4.4 +/- 0.3 ln-ms2 and high-frequency component, 2.6 +/- 0.3 ln-ms2 versus 2.2 +/- 0.3 ln-ms2.	Dobutamine	31-41	CD59 molecule (CD59 blood group)	Homo sapiens	68-78
7587003-4	1995	Compared to baseline, the renal magnesium excretion increased 30% during the infusion of insulin at a rate of 120 pmol m-2 min-1.	Magnesium	32-41	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
7587003-5	1995	During infusion of insulin, 240 pmol m-2 min-1, renal magnesium excretion increased 50% compared to baseline.	Magnesium	54-63	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
7489026-7	1995	Glucose MCR increased from a mean baseline value of 3.0 +/- 1.6 to 6.7 +/- 3.9 ml kg-1 min-1 at post GBO (P) (P < 0.02).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
8556223-7	1995	In urine only morphine and its glucuronides are found, with renal clearance values of 214 ml.min-1 for morphine and 132 ml.min-1 for the glucuronides.	Morphine	14-22	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8556223-7	1995	In urine only morphine and its glucuronides are found, with renal clearance values of 214 ml.min-1 for morphine and 132 ml.min-1 for the glucuronides.	Glucuronides	31-43	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8556223-7	1995	In urine only morphine and its glucuronides are found, with renal clearance values of 214 ml.min-1 for morphine and 132 ml.min-1 for the glucuronides.	Morphine	103-111	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8556223-7	1995	In urine only morphine and its glucuronides are found, with renal clearance values of 214 ml.min-1 for morphine and 132 ml.min-1 for the glucuronides.	Glucuronides	137-149	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
7579128-4	1995	histamine (0.5 microgram kg-1 min-1 for 20 min).	Histamine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
7543140-1	1995	This study investigates whether cell-derived glycosylphosphatidylinositol-linked complement control proteins CD55 and CD59 can be incorporated into HIV-1 virions and contribute to complement resistance.	Glycosylphosphatidylinositols	45-73	CD59 molecule (CD59 blood group)	Homo sapiens	118-122
7543140-10	1995	Phosphatidylinositol-specific phospholipase C treatment of either cell line-derived or primary isolates of HIV-1 increased sensitivity to complement while incubation of sensitive virus with purified CD55 and CD59 increased resistance to complement.	Phosphatidylinositols	0-20	CD59 molecule (CD59 blood group)	Homo sapiens	208-212
7552762-6	1995	Several lines of evidence, including earlier animal studies as well as more recent human studies, favor the expression of submaximal and maximal oxygen uptake during running in terms of ml.kg-0.75.min-1 rather than as ml.kg-1.min-1.	Oxygen	145-151	CD59 molecule (CD59 blood group)	Homo sapiens	197-202
7572010-3	1995	Therefore, we compared the acute effects of nitroglycerin (0.5 micrograms kg-1 min-1) and isosorbide dinitrate (0.5 or 2.5 micrograms kg-1 min-1) with those of placebo on platelet function both before and after cardiopulmonary bypass in 40 patients undergoing coronary artery bypass grafting (CABG).	Nitroglycerin	44-57	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
7572024-5	1995	During tumour manipulation the child became hypertensive with systolic pressure exceeding 130 mm Hg and adenosine infusion (100 micrograms.kg-1.min-1) was started with a prompt normalisation of the blood pressure.	Adenosine	104-113	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
8527690-6	1995	A high total body clearance (CL = 252 +/- 52 mL min-1) and short apparent elimination half-life (t/2e = 1.15 +/- 0.19 h) were expected for this polar quaternary ammonium drug.	quaternary ammonium drug	150-174	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
7669465-2	1995	Mivacurium chloride was infused at a rate of 15 micrograms kg-1 min-1 for 10 min, 7.5 micrograms kg-1 min-1 for a further 10 min, and then at a rate adjusted to maintain T1/T0 at 5%.	Mivacurium	0-19	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
7669469-5	1995	CBF before and during infusion of labetalol was 67 and 65 ml/100 g min-1, respectively (P > 0.05).	Labetalol	34-43	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
7553995-6	1995	Upon recovery of the twitch response from vecuronium, a mivacurium infusion was started at 4 micrograms.kg-1.min-1, thereafter adjustments were made to maintain the first twitch of the train-of-four (T1) at 1-10% of control.	Mivacurium	56-66	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
8527263-6	1995	The dose of isoprenaline required to increase heart rate by 25 beats min-1 (I25) and the dose of phenylephrine required to increase systolic and diastolic blood pressure by 20 mm Hg (PS20 and PD20) were calculated using a quadratic fit to individual dose-response curves.	Isoproterenol	12-24	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
7554772-5	1995	Pulmonary oxygen uptake increased from 209 +/- 11 to 267 +/- 13 ml min-1 in the patients and from 268 +/- 5 to 320 +/- 8 ml min-1 in the controls.	Oxygen	10-16	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
7671566-7	1995	Salt restriction increased the antidiuretic effect of arginine vasopressin (2 fmol min-1 kg-1 arginine vasopressin increased urine osmolality from 67.8 +/- 2.6 to 196.3 +/- 35.7 mosmol/l in the high-salt study and from 268.3 +/- 49 mosmol/l in the low-salt study; P < 0.05 between sodium intakes).	Salts	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	83-93
7671566-7	1995	Salt restriction increased the antidiuretic effect of arginine vasopressin (2 fmol min-1 kg-1 arginine vasopressin increased urine osmolality from 67.8 +/- 2.6 to 196.3 +/- 35.7 mosmol/l in the high-salt study and from 268.3 +/- 49 mosmol/l in the low-salt study; P < 0.05 between sodium intakes).	Salts	199-203	CD59 molecule (CD59 blood group)	Homo sapiens	83-93
7671566-7	1995	Salt restriction increased the antidiuretic effect of arginine vasopressin (2 fmol min-1 kg-1 arginine vasopressin increased urine osmolality from 67.8 +/- 2.6 to 196.3 +/- 35.7 mosmol/l in the high-salt study and from 268.3 +/- 49 mosmol/l in the low-salt study; P < 0.05 between sodium intakes).	Salts	252-256	CD59 molecule (CD59 blood group)	Homo sapiens	83-93
7671566-7	1995	Salt restriction increased the antidiuretic effect of arginine vasopressin (2 fmol min-1 kg-1 arginine vasopressin increased urine osmolality from 67.8 +/- 2.6 to 196.3 +/- 35.7 mosmol/l in the high-salt study and from 268.3 +/- 49 mosmol/l in the low-salt study; P < 0.05 between sodium intakes).	Sodium	284-290	CD59 molecule (CD59 blood group)	Homo sapiens	83-93
7542590-0	1995	The glycosylphosphatidylinositol-anchored CD59 protein stimulates both T cell receptor zeta/ZAP-70-dependent and -independent signaling pathways in T cells.	Glycosylphosphatidylinositols	4-32	CD59 molecule (CD59 blood group)	Homo sapiens	42-46
7542590-1	1995	The glycosylphosphatidylinositol (GPI)-anchored CD59 protein (human protectin) protects cells against complement-induced lysis, binds to CD2 and also transduces activation signals within T cells.	Glycosylphosphatidylinositols	4-32	CD59 molecule (CD59 blood group)	Homo sapiens	48-52
7542590-1	1995	The glycosylphosphatidylinositol (GPI)-anchored CD59 protein (human protectin) protects cells against complement-induced lysis, binds to CD2 and also transduces activation signals within T cells.	Glycosylphosphatidylinositols	34-37	CD59 molecule (CD59 blood group)	Homo sapiens	48-52
7542590-4	1995	Cross-linking of CD59 on peripheral T cells and thymocytes induces tyrosine phosphorylations identical to those seen in Jurkat cells and this is followed by lymphokine production and proliferation.	Tyrosine	67-75	CD59 molecule (CD59 blood group)	Homo sapiens	17-21
7542590-7	1995	CD59 cross-linking synergizes with sub-optimal doses of phorbol ester for activation of the protein kinase C and of the p42mapk, as shown by in vitro phosphorylation of histone HIIIS and myelin basic protein, respectively, and leads to CD25 but not CD69 expression.	Phorbol Esters	56-69	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
7588662-4	1995	Anaesthesia was maintained in the intravenous group by infusion of alfentanil 1-1.5 micrograms kg-1 min-1 and injections of midazolam 2.5-5 mg h-1, and in the inhalational group by isoflurane up to 2%.	Alfentanil	67-77	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
7588672-3	1995	One group received 0.05 micrograms kg-1 min-1 of PGE1, the second group received 0.1 microgram kg-1 min-1 of PGE1 just after the induction of anaesthesia, and the third group received no PGE1 during anaesthesia (control).	Alprostadil	109-113	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
7588672-3	1995	One group received 0.05 micrograms kg-1 min-1 of PGE1, the second group received 0.1 microgram kg-1 min-1 of PGE1 just after the induction of anaesthesia, and the third group received no PGE1 during anaesthesia (control).	Alprostadil	109-113	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
7588672-8	1995	This result suggests that 0.05 micrograms kg-1 min-1 of PGE1 may be superior to 0.1 microgram kg-1 min-1 of PGE1 for maintaining central and peripheral temperatures during surgery and general anaesthesia.	Alprostadil	56-60	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
7558140-0	1995	Shedding and enrichment of the glycolipid-anchored complement lysis inhibitor protectin (CD59) into milk fat globules.	Glycolipids	31-41	CD59 molecule (CD59 blood group)	Homo sapiens	89-93
7558140-1	1995	Protectin (CD59) is a glycolipid-anchored inhibitor of the membrane attack complex (MAC) of human complement (C) that protects blood cells, endothelial cells and various epithelial cells from C-mediated lysis.	Glycolipids	22-32	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
7553995-7	1995	The mean (+/- SE) initial infusion requirements in children of mivacurium was 4.3 (0.4) micrograms.kg-1.min-1 which increased linearly (P < 0.001) over the next 90 min to 10 micrograms.kg-1.min-1.	Mivacurium	63-73	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
7553995-7	1995	The mean (+/- SE) initial infusion requirements in children of mivacurium was 4.3 (0.4) micrograms.kg-1.min-1 which increased linearly (P < 0.001) over the next 90 min to 10 micrograms.kg-1.min-1.	Mivacurium	63-73	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
7569729-6	1995	Urinary sodium excretion rate increased in controls (0.23 to 0.52 mmol min-1, p < 0.01), while GFR increased (108 to 117 ml min-1, p < 0.05), and DFRNa decreased (93 to 89%, p < 0.01).	Sodium	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
7541422-8	1995	Metabolic labeling using [35S]cysteine showed that the molecular mass of CD59 in HMC was 20 kDa.	Sulfur-35	26-29	CD59 molecule (CD59 blood group)	Homo sapiens	73-77
7541422-8	1995	Metabolic labeling using [35S]cysteine showed that the molecular mass of CD59 in HMC was 20 kDa.	Cysteine	30-38	CD59 molecule (CD59 blood group)	Homo sapiens	73-77
7569729-9	1995	Sodium excretion increased in four of five patients without ascites (0.23 to 0.27 mmol min-1, medians).	Sodium	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
7654486-9	1995	Mean (95% CI) measurements for terfenadine vs placebo treatment periods were 1.5 vs 1.5 (-0.3, 0.3) l for FEV1, 259 vs 260 (-42, 40) l min-1 for morning PEF and 0.8 vs 0.8 (-0.3, 0.3) for global symptom scores.	Terfenadine	31-42	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
7572222-5	1995	Endurance training resulted in a significant increase in maximal oxygen uptake (L min-1) (P < 0.01).	Oxygen	65-71	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
7762853-5	1995	In the mirfentanil group (n = 8) the dose was increased in sequential subjects from 25 micrograms.kg-1.min-1 for 30 min to 450 micrograms.kg-1.min-1 for 15 min, and in the butorphanol group (n = 10) from 2 micrograms.kg-1.min-1 for 30 min to 25 micrograms.kg-1.min-1 for 15 min.	mirfentanil	7-18	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
7654491-3	1995	Probenecid significantly increased the t1/2,z of frusemide from 2.01 +/- 0.68 to 3.40 +/- 1.48 h (P = 0.0015) and significantly decreased oral clearance from 164 +/- 67.0 to 58.3 +/- 28.1 ml min-1 (P = 0.0001).	Probenecid	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
7654491-7	1995	However, probenecid decreased the renal clearance of both frusemide (128 +/- 49 vs 44.0 +/- 18.6 ml min-1, P = 0.0002) and the acyl glucuronide (552 +/- 298 vs 158 +/- 94.0 ml min-1, P < 0.0001).	Probenecid	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
7654491-7	1995	However, probenecid decreased the renal clearance of both frusemide (128 +/- 49 vs 44.0 +/- 18.6 ml min-1, P = 0.0002) and the acyl glucuronide (552 +/- 298 vs 158 +/- 94.0 ml min-1, P < 0.0001).	Probenecid	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
7654491-8	1995	The non-renal clearance of frusemide (36.7 +/- 21.0 vs 15.2 +/- 13.4 ml min-1, P = 0.0068) was also decreased.	Furosemide	27-36	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
8547853-10	1995	The water-soluble fraction contained a substance with hRf = 20 which was the same as that of authentic SMFA.	Water	4-9	CD59 molecule (CD59 blood group)	Homo sapiens	54-62
7781369-11	1995	Gas exchange rates averaged 50.4 +/- 15.8 mL.min-1 for carbon dioxide and 71.1 +/- 20.2 mL.min-1 for oxygen.	Carbon Dioxide	55-69	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
7781369-11	1995	Gas exchange rates averaged 50.4 +/- 15.8 mL.min-1 for carbon dioxide and 71.1 +/- 20.2 mL.min-1 for oxygen.	Oxygen	101-107	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
7656918-4	1995	During the IGF-I infusion glucose appearance rate (Ra) decreased from 1.79 +/- 0.13 at baseline (150-180 min) to 0.35 +/- 0.26 mg kg-1 min-1 (P < 0.01) at 360 min, and glucose utilization rate (Rd) increased from 1.79 +/- 0.28 to 4.17 +/- 0.84 mg kg-1 min-1 (P < 0.01).	Glucose	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
7656918-6	1995	During the insulin infusion glucose Ra decreased from 1.89 +/- 0.13 to 0.34 +/- 0.33 mg kg-1 min-1 (P < 0.01) and FFA from 0.546 mmol l-1 to 0.198 mmol l-1 (P < 0.01), glucose Rd increased from 1.89 +/- 0.18 to 5.41 +/- 1.47 mg kg-1 min-1 (P < 0.01) and there were no significant changes in the cardiovascular variables.	Glucose	28-35	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
7655200-4	1995	PATIENTS AND METHODS: Between 2 to 6 h after topical fluorescein application, the time-dependent decrease in dye concentration ratio between aqueous and anterior vitreous leads to the diffusion rate D(av) [10(-3)min-1] between aqueous and vitreous; D(av) was evaluated fluorophotometrically before and 3 weeks after capsulotomy (3 to 5 mm) in human eyes of each group.	Fluorescein	53-64	CD59 molecule (CD59 blood group)	Homo sapiens	212-217
7537958-0	1995	Enhanced complement susceptibility of avidin-biotin-treated human erythrocytes is a consequence of neutralization of the complement regulators CD59 and decay accelerating factor.	avidin-biotin	38-51	CD59 molecule (CD59 blood group)	Homo sapiens	143-147
7538980-3	1995	SDS-PAGE analysis showed that the molecular weight of CD59 expressed on melanoma cells is about 20 kDa.	Sodium Dodecyl Sulfate	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	54-58
7538980-4	1995	Treatment of melanoma cells with 5U/ml of phosphatidylinositol-specific phospholipase C completely abolished cell-surface expression of CD59.	Phosphatidylinositols	42-62	CD59 molecule (CD59 blood group)	Homo sapiens	136-140
7741287-11	1995	Part II: The HR in the control group increased by more than 20 beats.min-1 in response to atropine 20 micrograms.kg-1 or less.	Atropine	90-98	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
7741287-14	1995	A larger dose of atropine was required to increase the HR by 20 beats.min-1 in children receiving the premedicant in the larger dose.	Atropine	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
7741300-17	1995	Rate constants were 1.46 x 10(-9) ppm-2.min-1 when NO was mixed with N2, 1.17 x 10(-8) ppm-2.min-1 when NO was blended with air, and 1.44 x 10(-9) ppm-2.min-1 in the test lung.	Nitrogen	69-71	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
7545610-0	1995	Exogenous CD59 incorporated into U937 cells through its glycosyl phosphatidylinositol anchor becomes associated with signalling molecules in a time dependent manner.	Glycosylphosphatidylinositols	56-85	CD59 molecule (CD59 blood group)	Homo sapiens	10-14
7669483-8	1995	administration of 1200 mg celiprolol (n = 15) caused evident chrono-inodilatory responses: average HR increases of 7, 19, 10, 17, 17 and 8 beats min-1, estimated CO increases of 1.6, 4.5, 2.3, 1.9, 2.6 and 1.8 1 min-1 and average shortening of QS2c of 18, 41, 8, 37, 42 and 9 ms for food, isoprenaline, adrenaline, isomazole, meribendan and celiprolol, respectively.	Celiprolol	26-36	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
7669483-8	1995	administration of 1200 mg celiprolol (n = 15) caused evident chrono-inodilatory responses: average HR increases of 7, 19, 10, 17, 17 and 8 beats min-1, estimated CO increases of 1.6, 4.5, 2.3, 1.9, 2.6 and 1.8 1 min-1 and average shortening of QS2c of 18, 41, 8, 37, 42 and 9 ms for food, isoprenaline, adrenaline, isomazole, meribendan and celiprolol, respectively.	Celiprolol	26-36	CD59 molecule (CD59 blood group)	Homo sapiens	212-217
7621647-4	1995	During infusion of dobutamine up to 40 micrograms kg-1 min-1, arterial pressure was maintained near baseline levels, whereas heart rate and cardiac index increased, more so in group 1 (mean: 89 and 79%) than in group 2 (58 and 52%; P < 0.05 vs. group 1).	Dobutamine	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
7588904-2	1995	In 250 patients who underwent left and right heart catheterization, the oxygen consumption VO2 (ml.min-1) was calculated using Fick"s principle.	Oxygen	72-78	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
7588904-2	1995	In 250 patients who underwent left and right heart catheterization, the oxygen consumption VO2 (ml.min-1) was calculated using Fick"s principle.	vo2	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
7543624-1	1995	Protectin (CD59) is a low molecular weight glycophosphoinositol-anchored inhibitor of the membrane attack complex of complement (MAC) that is present, for example, on the membranes of endothelial cells and on epithelial cells of glomeruli and distal tubuli.	glycophosphoinositol	43-63	CD59 molecule (CD59 blood group)	Homo sapiens	0-9
7537958-3	1995	We set out to examine the mechanisms of this biotin-avidin-induced lytic susceptibility, focusing on the effects of biotinylation and avidin cross-linking on the major E complement regulatory molecules, decay accelerating factor (DAF) and CD59.	Biotin	45-51	CD59 molecule (CD59 blood group)	Homo sapiens	239-243
7543447-0	1995	Regulation of CD59 expression on K562 cells: effects of phorbol myristate acetate, cross-linking antibody and non-lethal complement attack.	Tetradecanoylphorbol Acetate	56-81	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
7543447-3	1995	We have chosen the K562 erythroleukaemia cell line as a model for studies of the regulation of CD59 expression, because it has previously been reported that phorbol 12-myristate 13-acetate (PMA) caused a 15-fold up-regulation of CD59 mRNA in these cells, implying a substantial capacity for CD59 synthesis.	Tetradecanoylphorbol Acetate	157-188	CD59 molecule (CD59 blood group)	Homo sapiens	95-99
7543447-3	1995	We have chosen the K562 erythroleukaemia cell line as a model for studies of the regulation of CD59 expression, because it has previously been reported that phorbol 12-myristate 13-acetate (PMA) caused a 15-fold up-regulation of CD59 mRNA in these cells, implying a substantial capacity for CD59 synthesis.	Tetradecanoylphorbol Acetate	157-188	CD59 molecule (CD59 blood group)	Homo sapiens	229-233
7543447-3	1995	We have chosen the K562 erythroleukaemia cell line as a model for studies of the regulation of CD59 expression, because it has previously been reported that phorbol 12-myristate 13-acetate (PMA) caused a 15-fold up-regulation of CD59 mRNA in these cells, implying a substantial capacity for CD59 synthesis.	Tetradecanoylphorbol Acetate	157-188	CD59 molecule (CD59 blood group)	Homo sapiens	229-233
7543447-3	1995	We have chosen the K562 erythroleukaemia cell line as a model for studies of the regulation of CD59 expression, because it has previously been reported that phorbol 12-myristate 13-acetate (PMA) caused a 15-fold up-regulation of CD59 mRNA in these cells, implying a substantial capacity for CD59 synthesis.	Tetradecanoylphorbol Acetate	190-193	CD59 molecule (CD59 blood group)	Homo sapiens	95-99
7543447-3	1995	We have chosen the K562 erythroleukaemia cell line as a model for studies of the regulation of CD59 expression, because it has previously been reported that phorbol 12-myristate 13-acetate (PMA) caused a 15-fold up-regulation of CD59 mRNA in these cells, implying a substantial capacity for CD59 synthesis.	Tetradecanoylphorbol Acetate	190-193	CD59 molecule (CD59 blood group)	Homo sapiens	229-233
7543447-3	1995	We have chosen the K562 erythroleukaemia cell line as a model for studies of the regulation of CD59 expression, because it has previously been reported that phorbol 12-myristate 13-acetate (PMA) caused a 15-fold up-regulation of CD59 mRNA in these cells, implying a substantial capacity for CD59 synthesis.	Tetradecanoylphorbol Acetate	190-193	CD59 molecule (CD59 blood group)	Homo sapiens	229-233
7543447-6	1995	The newly expressed CD59 was functionally active and anchored through glycosyl-phosphatidylinositol (GPI).	Glycosylphosphatidylinositols	70-99	CD59 molecule (CD59 blood group)	Homo sapiens	20-24
7543447-6	1995	The newly expressed CD59 was functionally active and anchored through glycosyl-phosphatidylinositol (GPI).	Glycosylphosphatidylinositols	101-104	CD59 molecule (CD59 blood group)	Homo sapiens	20-24
7543624-1	1995	Protectin (CD59) is a low molecular weight glycophosphoinositol-anchored inhibitor of the membrane attack complex of complement (MAC) that is present, for example, on the membranes of endothelial cells and on epithelial cells of glomeruli and distal tubuli.	glycophosphoinositol	43-63	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
7543624-5	1995	Using a Triton X-114 phase separation method 91 to 97% of urinary CD59 was found to be in a soluble form without anchor-associated phospholipid.	Nonidet P-40	8-20	CD59 molecule (CD59 blood group)	Homo sapiens	66-70
7630652-6	1995	The VCO2 l min-1 for AC (2.00 +/- 0.20 l min-1) and TM (2.00 +/- 0.12 l min-1) was also not significantly different.	Charcoal	21-23	CD59 molecule (CD59 blood group)	Homo sapiens	11-16
7493608-1	1995	Local intra-arterial infusion of high doses of the nitric oxide (NO) donor, nitroprusside (10-40 micrograms kg-1 min-1 for 15 min) induced dose-dependent haemorrhagic injury to the rat gastric mucosa and reduced systemic arterial blood pressure, whereas intragastric nitroprusside (10-50 mg ml-1), which caused similar falls in blood pressure, failed to induce such injury.	Nitric Oxide	51-63	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
7493608-1	1995	Local intra-arterial infusion of high doses of the nitric oxide (NO) donor, nitroprusside (10-40 micrograms kg-1 min-1 for 15 min) induced dose-dependent haemorrhagic injury to the rat gastric mucosa and reduced systemic arterial blood pressure, whereas intragastric nitroprusside (10-50 mg ml-1), which caused similar falls in blood pressure, failed to induce such injury.	Nitroprusside	76-89	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
7493608-4	1995	Local superoxide dismutase also abolished the mucosal injury induced by local infusion of the NO donor, S-nitroso-N-acetyl-penicillamine (40 micrograms kg-1 min-1), but not that induced by local infusion of endothelin-1 (5 pmol kg-1 min-1) indicating specific actions.	S-Nitroso-N-Acetylpenicillamine	104-136	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
7727522-3	1995	Ten cytosols formed the S,S"-ethylenebis(GSH) conjugate at a rate ranging from 0.5 to 3.2 (mean 1.76 +/- 0.95) pmol min-1 (mg protein)-1.	Sulfur	24-25	CD59 molecule (CD59 blood group)	Homo sapiens	116-136
7727522-3	1995	Ten cytosols formed the S,S"-ethylenebis(GSH) conjugate at a rate ranging from 0.5 to 3.2 (mean 1.76 +/- 0.95) pmol min-1 (mg protein)-1.	Glutathione	41-44	CD59 molecule (CD59 blood group)	Homo sapiens	116-136
7727522-6	1995	Every cytosol was active with the classical GST substrate CDNB (2.04 +/- 0.74 nmol min-1 (mg protein)-1).	Dinitrochlorobenzene	58-62	CD59 molecule (CD59 blood group)	Homo sapiens	83-103
7717560-10	1995	Propofol was administered (bolus 2 mg/kg + 120 micrograms.kg-1.min-1), and the electrophysiologic measurements were repeated.	Propofol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
7771674-1	1995	Flow injection (FI), at a flow rate of microliter min-1, is an effective method for enzymic substrate determination using low concentrations of poly(ethylene glycol) (PEG)-stabilized soluble enzymes.	Polyethylene Glycols	167-170	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
7771674-5	1995	The determination of several substrates such as pyruvate, lactate, and cortisone using appropriate PEG-stabilized enzymes is demonstrated with this FI instrument at 25 or 50 microliters min-1 with sample throughputs of the order of 2-3 min per sample.	Pyruvic Acid	48-56	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
7771674-5	1995	The determination of several substrates such as pyruvate, lactate, and cortisone using appropriate PEG-stabilized enzymes is demonstrated with this FI instrument at 25 or 50 microliters min-1 with sample throughputs of the order of 2-3 min per sample.	Lactic Acid	58-65	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
7771674-5	1995	The determination of several substrates such as pyruvate, lactate, and cortisone using appropriate PEG-stabilized enzymes is demonstrated with this FI instrument at 25 or 50 microliters min-1 with sample throughputs of the order of 2-3 min per sample.	Cortisone	71-80	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
7771674-5	1995	The determination of several substrates such as pyruvate, lactate, and cortisone using appropriate PEG-stabilized enzymes is demonstrated with this FI instrument at 25 or 50 microliters min-1 with sample throughputs of the order of 2-3 min per sample.	Polyethylene Glycols	99-102	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
7763134-6	1995	Everted membrane vesicles catalyzed hydrogen-dependent glyoxylate reduction to glycolate [86-207 nmol min-1 (mg protein)-1] coupled to ATP synthesis from ADP and Pi [38-82 nmol min-1 (mg protein)-1)].	Hydrogen	36-44	CD59 molecule (CD59 blood group)	Homo sapiens	102-122
7763134-6	1995	Everted membrane vesicles catalyzed hydrogen-dependent glyoxylate reduction to glycolate [86-207 nmol min-1 (mg protein)-1] coupled to ATP synthesis from ADP and Pi [38-82 nmol min-1 (mg protein)-1)].	Hydrogen	36-44	CD59 molecule (CD59 blood group)	Homo sapiens	177-197
7763134-6	1995	Everted membrane vesicles catalyzed hydrogen-dependent glyoxylate reduction to glycolate [86-207 nmol min-1 (mg protein)-1] coupled to ATP synthesis from ADP and Pi [38-82 nmol min-1 (mg protein)-1)].	glyoxylic acid	55-65	CD59 molecule (CD59 blood group)	Homo sapiens	102-122
7763134-6	1995	Everted membrane vesicles catalyzed hydrogen-dependent glyoxylate reduction to glycolate [86-207 nmol min-1 (mg protein)-1] coupled to ATP synthesis from ADP and Pi [38-82 nmol min-1 (mg protein)-1)].	glyoxylic acid	55-65	CD59 molecule (CD59 blood group)	Homo sapiens	177-197
7763134-6	1995	Everted membrane vesicles catalyzed hydrogen-dependent glyoxylate reduction to glycolate [86-207 nmol min-1 (mg protein)-1] coupled to ATP synthesis from ADP and Pi [38-82 nmol min-1 (mg protein)-1)].	glycolic acid	79-88	CD59 molecule (CD59 blood group)	Homo sapiens	102-122
7763134-6	1995	Everted membrane vesicles catalyzed hydrogen-dependent glyoxylate reduction to glycolate [86-207 nmol min-1 (mg protein)-1] coupled to ATP synthesis from ADP and Pi [38-82 nmol min-1 (mg protein)-1)].	glycolic acid	79-88	CD59 molecule (CD59 blood group)	Homo sapiens	177-197
7763134-6	1995	Everted membrane vesicles catalyzed hydrogen-dependent glyoxylate reduction to glycolate [86-207 nmol min-1 (mg protein)-1] coupled to ATP synthesis from ADP and Pi [38-82 nmol min-1 (mg protein)-1)].	Adenosine Triphosphate	135-138	CD59 molecule (CD59 blood group)	Homo sapiens	102-122
7763134-6	1995	Everted membrane vesicles catalyzed hydrogen-dependent glyoxylate reduction to glycolate [86-207 nmol min-1 (mg protein)-1] coupled to ATP synthesis from ADP and Pi [38-82 nmol min-1 (mg protein)-1)].	Adenosine Triphosphate	135-138	CD59 molecule (CD59 blood group)	Homo sapiens	177-197
7763134-6	1995	Everted membrane vesicles catalyzed hydrogen-dependent glyoxylate reduction to glycolate [86-207 nmol min-1 (mg protein)-1] coupled to ATP synthesis from ADP and Pi [38-82 nmol min-1 (mg protein)-1)].	Adenosine Diphosphate	154-157	CD59 molecule (CD59 blood group)	Homo sapiens	102-122
7734262-5	1995	We conclude that dobutamine and dopamine are equipotent inotropes in children and that dopamine in doses > 7 micrograms kg-1 min-1, caused pulmonary vasoconstriction, an effect mediated by alpha adrenergic receptors.	Dopamine	87-95	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
7534714-4	1995	Flow-cytometric analysis revealed a normal expression of GPI-linked membrane proteins, including CD55, CD59, and CD16 on PMN in all patients treated with CyA, irrespective of response, except for one patient who had a small proportion of GPI-anchored membrane protein-negative cells before therapy.	Cyclosporine	154-157	CD59 molecule (CD59 blood group)	Homo sapiens	103-107
7601204-2	1995	infusion of urodilatin at a dose of 30 ng kg-1 min-1 were studied in a patient with congestive heart failure.	Ularitide	12-22	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
7650077-4	1995	Urinary Clcr ranged from 0 to 161 ml/min/1.73 m2.	clcr	8-12	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
7650077-11	1995	Clcr (ml/min/1.73 m2) = (0.52 x height (cm)/serum creatinine)--3.6 was the best equation for estimating Clcr in our patient population consisting of children over 7 years of age with stable serum creatinine.	clcr	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	9-14
7536884-4	1995	In agreement with previous findings, significant increments in plasma cortisol levels were observed in men and women when the higher (1.5 pmol/kg-1/min-1) but not the lower (0.5 pmol/kg-1/min-1) amount of SP was administered.	Hydrocortisone	70-78	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
7536884-4	1995	In agreement with previous findings, significant increments in plasma cortisol levels were observed in men and women when the higher (1.5 pmol/kg-1/min-1) but not the lower (0.5 pmol/kg-1/min-1) amount of SP was administered.	Hydrocortisone	70-78	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
7630652-6	1995	The VCO2 l min-1 for AC (2.00 +/- 0.20 l min-1) and TM (2.00 +/- 0.12 l min-1) was also not significantly different.	Charcoal	21-23	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
7630652-6	1995	The VCO2 l min-1 for AC (2.00 +/- 0.20 l min-1) and TM (2.00 +/- 0.12 l min-1) was also not significantly different.	Charcoal	21-23	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
7605941-3	1995	Adenosine (50 micrograms kg-1 min-1) or saline was given intravenously for 20 min before the mustard oil application and continued for another 50 min.	Adenosine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
7776513-6	1995	Diltiazem infusion of 4 mcg.kg-1.min-1 decreased the vecuronium infusion rate by 45% compared with 2 other groups.	Diltiazem	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
7776513-6	1995	Diltiazem infusion of 4 mcg.kg-1.min-1 decreased the vecuronium infusion rate by 45% compared with 2 other groups.	Vecuronium Bromide	53-63	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
7776513-7	1995	Plasma diltiazem concentrations in patients receiving 4 mcg.kg-1.min-1 were significantly higher than those receiving 2 mcg.kg-1.min-1.	Diltiazem	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
7776513-8	1995	In conclusion diltiazem 4 mcg.kg-1.min-1 potentiates the neuromuscular blockade of vecuronium and it relates with the plasma diltiazem concentration.	Diltiazem	14-23	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
7776513-8	1995	In conclusion diltiazem 4 mcg.kg-1.min-1 potentiates the neuromuscular blockade of vecuronium and it relates with the plasma diltiazem concentration.	Vecuronium Bromide	83-93	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
7776513-8	1995	In conclusion diltiazem 4 mcg.kg-1.min-1 potentiates the neuromuscular blockade of vecuronium and it relates with the plasma diltiazem concentration.	Diltiazem	125-134	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
7532041-1	1995	The lack of glycosylphosphatidylinositol (GPI)-anchored membrane proteins such as decay-accelerating factor (DAF) and CD59 on blood cells has a diagnostic value in paroxysmal nocturnal hemoglobinuria (PNH).	Glycosylphosphatidylinositols	42-45	CD59 molecule (CD59 blood group)	Homo sapiens	118-122
7888673-4	1995	DHG inhibited the amidolytic activity of thrombin in the presence of HCII with a second order rate constant of 1.2 x 10(8) (mol/L)-1 min-1.	dhg	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
7718371-3	1995	We measured changes in gastric intramucosal pH, splanchnic blood flow and oxygen transport in response to increased systemic flow induced by dobutamine (mean 4.4 (range 3.0-7.0) micrograms kg-1 min-1) after coronary artery bypass.	Dobutamine	141-151	CD59 molecule (CD59 blood group)	Homo sapiens	194-199
7619676-3	1995	Mean urinary excretion rate of 5-HT, which was < 0.7 nmol min-1 before dosing, rose to a peak value of 412 +/- 92 nmol min-1 at the end of 5-HTP infusion and 303 +/- 29 nmol min-1 after administration of glu-5-HTP.	5-Hydroxytryptophan	142-147	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
7619676-3	1995	Mean urinary excretion rate of 5-HT, which was < 0.7 nmol min-1 before dosing, rose to a peak value of 412 +/- 92 nmol min-1 at the end of 5-HTP infusion and 303 +/- 29 nmol min-1 after administration of glu-5-HTP.	5-Hydroxytryptophan	142-147	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
7619676-3	1995	Mean urinary excretion rate of 5-HT, which was < 0.7 nmol min-1 before dosing, rose to a peak value of 412 +/- 92 nmol min-1 at the end of 5-HTP infusion and 303 +/- 29 nmol min-1 after administration of glu-5-HTP.	gamma-glutamyl-5-hydroxytryptophan	207-216	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
7619676-3	1995	Mean urinary excretion rate of 5-HT, which was < 0.7 nmol min-1 before dosing, rose to a peak value of 412 +/- 92 nmol min-1 at the end of 5-HTP infusion and 303 +/- 29 nmol min-1 after administration of glu-5-HTP.	gamma-glutamyl-5-hydroxytryptophan	207-216	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
7736695-2	1995	We tested the effect of intravenous adrenaline at 0.55-1.10 nmol min-1 kg-1 (for 3-8 min, at 7-10 min post bypass; n = 7) on both microaggregation in hirudinized whole blood, using platelet counting, and macroaggregation in platelet-rich plasma, using optical aggregometry.	Epinephrine	36-46	CD59 molecule (CD59 blood group)	Homo sapiens	65-75
7758258-3	1995	The insulin sensitivity was assessed by the insulin (0.4 mU kg-1 min-1)-glucose/(4.5 mg kg-1 min-1)-infusion test (IGIT).	Glucose	72-79	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
7758259-6	1995	The increase in fractional excretion of sodium during a 1 h low-dose dopamine (3 micrograms kg-1 min-1) infusion in Type 1 diabetic patients was negatively correlated with diabetes duration.	Sodium	40-46	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
7758259-6	1995	The increase in fractional excretion of sodium during a 1 h low-dose dopamine (3 micrograms kg-1 min-1) infusion in Type 1 diabetic patients was negatively correlated with diabetes duration.	Dopamine	69-77	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
7869211-2	1995	Plasma morphine clearances ranged from 6.2 to 59.1 ml min-1 kg-1 (35.5 +/- 12.4, mean +/- SD) during steady-state infusions.	Morphine	7-15	CD59 molecule (CD59 blood group)	Homo sapiens	54-64
7885270-5	1995	In both thalassemic groups, SI was reduced by approximately 40% (3.52 +/- 0.57 and 3.74 +/- 0.66 v 6.89 +/- 1.02 10(-4).min-1 [microU/mL], P = .011) and was inversely correlated with iron overload (r = -.707, P = .006).	Iron	183-187	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
7536892-0	1995	Determination of the active site of CD59 with synthetic peptides.	Peptides	56-64	CD59 molecule (CD59 blood group)	Homo sapiens	36-40
7536892-2	1995	Considering five disulfide bridges of CD59, we divided the molecule into two portions and synthesized the two peptides.	Disulfides	17-26	CD59 molecule (CD59 blood group)	Homo sapiens	38-42
7770236-7	1995	However, 99Tcm-DTPA clearance was 1.91 +/- 0.27% min-1 and 99Tcm-HMPAO clearance 0.78 +/- 0.17% min-1 in eight patients with IPF (P < 0.001, 99Tcm-DTPA vs 99Tcm-HMPAO).	99tcm-dtpa	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7770236-7	1995	However, 99Tcm-DTPA clearance was 1.91 +/- 0.27% min-1 and 99Tcm-HMPAO clearance 0.78 +/- 0.17% min-1 in eight patients with IPF (P < 0.001, 99Tcm-DTPA vs 99Tcm-HMPAO).	-dtpa	14-19	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7617521-6	1995	The Michaelis-Menten parameters for the active transport component (Km = 1.67 mM, Vmax = 26.5 pmol min-1 mg protein-1) indicate an involvement of the intestinal di/tripeptide transport system for one of the TI.	tripeptide K-26	164-174	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
7533195-0	1995	A rapid method for the isolation of analogues of human CD59 by preparative SDS-PAGE: application to pig CD59.	Sodium Dodecyl Sulfate	75-78	CD59 molecule (CD59 blood group)	Homo sapiens	55-59
7876094-9	1995	Phorbol ester up-regulated the Vmax of system B in 2-day-old cells to Vmax = 6.32 +/- 0.37 nmol min-1 mg of protein-1 (Km = 169 +/- 18 microM), and in 9-day-old cells to Vmax = 1.42 +/- 0.05 nmole min-1 mg of protein-1 (Km = 180 +/- 10 microM).	Phorbol Esters	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
7876094-9	1995	Phorbol ester up-regulated the Vmax of system B in 2-day-old cells to Vmax = 6.32 +/- 0.37 nmol min-1 mg of protein-1 (Km = 169 +/- 18 microM), and in 9-day-old cells to Vmax = 1.42 +/- 0.05 nmole min-1 mg of protein-1 (Km = 180 +/- 10 microM).	Phorbol Esters	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	197-202
7873595-4	1995	Data-base search showed similarity of pNiXc to eukaryotic aldolases, with 96% identity to human aldolase A. pNiXc demonstrated aldolase activity with fructose 1,6-bisphosphate as substrate (Km, 30 microM Vmax 26 mumol min-1 mg-1); the aldolase activity was inhibited non-competitively by Cu2+, Cd2+, Co2+, or Ni2+.	fructose-1,6-diphosphate	150-175	CD59 molecule (CD59 blood group)	Homo sapiens	218-228
7873595-4	1995	Data-base search showed similarity of pNiXc to eukaryotic aldolases, with 96% identity to human aldolase A. pNiXc demonstrated aldolase activity with fructose 1,6-bisphosphate as substrate (Km, 30 microM Vmax 26 mumol min-1 mg-1); the aldolase activity was inhibited non-competitively by Cu2+, Cd2+, Co2+, or Ni2+.	cupric ion	288-292	CD59 molecule (CD59 blood group)	Homo sapiens	218-228
7873595-4	1995	Data-base search showed similarity of pNiXc to eukaryotic aldolases, with 96% identity to human aldolase A. pNiXc demonstrated aldolase activity with fructose 1,6-bisphosphate as substrate (Km, 30 microM Vmax 26 mumol min-1 mg-1); the aldolase activity was inhibited non-competitively by Cu2+, Cd2+, Co2+, or Ni2+.	Cobalt(2+)	300-304	CD59 molecule (CD59 blood group)	Homo sapiens	218-228
7873595-4	1995	Data-base search showed similarity of pNiXc to eukaryotic aldolases, with 96% identity to human aldolase A. pNiXc demonstrated aldolase activity with fructose 1,6-bisphosphate as substrate (Km, 30 microM Vmax 26 mumol min-1 mg-1); the aldolase activity was inhibited non-competitively by Cu2+, Cd2+, Co2+, or Ni2+.	Nickel(2+)	309-313	CD59 molecule (CD59 blood group)	Homo sapiens	218-228
7743216-5	1995	On SH-SY5Y cells, both PCR amplification and immunocytochemistry demonstrated the presence of CD59, a glycosylphosphatidylinositol-anchored protein that restricts homologous complement activation by inhibiting the formation of the membrane attack complex.	Glycosylphosphatidylinositols	102-130	CD59 molecule (CD59 blood group)	Homo sapiens	94-98
7710018-5	1995	Intratracheal jet-ventilation (rate: 20 breath.min-1) was with 100% oxygen.	Oxygen	68-74	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
7696059-3	1995	Isoflurane reduced the initial increase in ventilation significantly by 3.12 (95% confidence limits 1.69, 4.55) litre min-1 (P < 0.05) and domperidone increased the initial increase in ventilation by 1.78 (0.35, 3.21) litre min-1 (P < 0.05).	Isoflurane	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
7696059-3	1995	Isoflurane reduced the initial increase in ventilation significantly by 3.12 (95% confidence limits 1.69, 4.55) litre min-1 (P < 0.05) and domperidone increased the initial increase in ventilation by 1.78 (0.35, 3.21) litre min-1 (P < 0.05).	Domperidone	142-153	CD59 molecule (CD59 blood group)	Homo sapiens	227-232
7696062-5	1995	Dopexamine administration significantly increased splanchnic blood flow (0.72 vs 1.02 litre min-1 m-2) (P < 0.05) and oxygen delivery (117 vs 161 ml min-1 m-2) (P < 0.05) compared with baseline values.	dopexamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
7696062-5	1995	Dopexamine administration significantly increased splanchnic blood flow (0.72 vs 1.02 litre min-1 m-2) (P < 0.05) and oxygen delivery (117 vs 161 ml min-1 m-2) (P < 0.05) compared with baseline values.	dopexamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
7696062-8	1995	In the control group there were no changes in splanchnic blood flow and oxygen delivery, while splanchnic oxygen consumption increased (36 vs 39 ml min-1 m-2) (P < 0.05) and gastric mucosal pH tended to decrease (7.33 vs 7.29) (ns).	Oxygen	106-112	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
7735684-11	1995	In the presence of the NO synthase inhibitor, NG-nitro-L-arginine methyl ester (L-NAME, 183 nmol kg-1 min-1), there was only a slight, but significant, inhibition of the hindquarters hyperaemic vasodilator effect of human adrenomedullin, but not that of human alpha-CGRP.	NG-Nitroarginine Methyl Ester	46-78	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
7735684-11	1995	In the presence of the NO synthase inhibitor, NG-nitro-L-arginine methyl ester (L-NAME, 183 nmol kg-1 min-1), there was only a slight, but significant, inhibition of the hindquarters hyperaemic vasodilator effect of human adrenomedullin, but not that of human alpha-CGRP.	NG-Nitroarginine Methyl Ester	80-86	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
7742150-6	1995	After oral enalapril 10 mg the absolute fall in serum ACE activity was significantly larger in DD than II subjects at 2, 4, and 6 h (by 9.0 (95% CI 0.7-17.2), 10.7 (3.8-17.6), and 9.7 (2.8-16.6) nmol ml-1 min-1 respectively), but not at 24 h (fall in II > DD by 1.1 (-8.9 to 6.7) nmol ml-1 min-1).	Enalapril	11-20	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
7742150-6	1995	After oral enalapril 10 mg the absolute fall in serum ACE activity was significantly larger in DD than II subjects at 2, 4, and 6 h (by 9.0 (95% CI 0.7-17.2), 10.7 (3.8-17.6), and 9.7 (2.8-16.6) nmol ml-1 min-1 respectively), but not at 24 h (fall in II > DD by 1.1 (-8.9 to 6.7) nmol ml-1 min-1).	Enalapril	11-20	CD59 molecule (CD59 blood group)	Homo sapiens	293-298
7742154-8	1995	of roxatidine was 10.8 +/- 2.4 h and its oral clearance was 178 +/- 43 ml min-1.	roxatidine acetate	3-13	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
7536646-4	1995	Synthase activity was significantly higher in patients with sepsis than in control subjects (1202 +/- 579 compared with 595 +/- 544 pmol of nitric oxide min-1 mg-1 of cell protein, P < 0.05).	Nitric Oxide	140-152	CD59 molecule (CD59 blood group)	Homo sapiens	153-163
7536646-6	1995	Activity was greatest in those patients with the larger number of organ failures, although this failed to reach significance (1489 +/- 560 in patients with three or more organ failures and 843 +/- 404 pmol of nitric oxide min-1 mg-1 of cell protein in those with less than three, P = 0.11).	Nitric Oxide	209-221	CD59 molecule (CD59 blood group)	Homo sapiens	222-232
7629042-8	1995	A steady-state kinetic analysis of the latent ATP synthase complex at various concentrations of ATP showed a Vmax of 1.28 mumol min-1 mg-1, whereas the Vmax of the complex without the inhibitor was 8.3 mumol min-1 mg-1.	Adenosine Triphosphate	46-49	CD59 molecule (CD59 blood group)	Homo sapiens	128-138
7629042-8	1995	A steady-state kinetic analysis of the latent ATP synthase complex at various concentrations of ATP showed a Vmax of 1.28 mumol min-1 mg-1, whereas the Vmax of the complex without the inhibitor was 8.3 mumol min-1 mg-1.	Adenosine Triphosphate	46-49	CD59 molecule (CD59 blood group)	Homo sapiens	208-218
7773302-6	1995	The predominant formation of the S- over the R-glucuronide was reflected by the kinetic parameters: For (S)oxazepam glucuronide, the constants were Km = 0.18 +/- 0.02 mM and Vmax = 202.6 +/- 25.0 nmol min-1 per mg protein; for (R)oxazepam glucuronide, they were Km = 0.22 +/- 0.02 mM, Vmax = 55.4 +/- 9.5 nmol min-1 per mg protein.	r-glucuronide	45-58	CD59 molecule (CD59 blood group)	Homo sapiens	201-206
7773302-6	1995	The predominant formation of the S- over the R-glucuronide was reflected by the kinetic parameters: For (S)oxazepam glucuronide, the constants were Km = 0.18 +/- 0.02 mM and Vmax = 202.6 +/- 25.0 nmol min-1 per mg protein; for (R)oxazepam glucuronide, they were Km = 0.22 +/- 0.02 mM, Vmax = 55.4 +/- 9.5 nmol min-1 per mg protein.	r-glucuronide	45-58	CD59 molecule (CD59 blood group)	Homo sapiens	310-315
7773302-6	1995	The predominant formation of the S- over the R-glucuronide was reflected by the kinetic parameters: For (S)oxazepam glucuronide, the constants were Km = 0.18 +/- 0.02 mM and Vmax = 202.6 +/- 25.0 nmol min-1 per mg protein; for (R)oxazepam glucuronide, they were Km = 0.22 +/- 0.02 mM, Vmax = 55.4 +/- 9.5 nmol min-1 per mg protein.	oxazepam glucuronide	104-127	CD59 molecule (CD59 blood group)	Homo sapiens	201-206
7773302-6	1995	The predominant formation of the S- over the R-glucuronide was reflected by the kinetic parameters: For (S)oxazepam glucuronide, the constants were Km = 0.18 +/- 0.02 mM and Vmax = 202.6 +/- 25.0 nmol min-1 per mg protein; for (R)oxazepam glucuronide, they were Km = 0.22 +/- 0.02 mM, Vmax = 55.4 +/- 9.5 nmol min-1 per mg protein.	oxazepam glucuronide	104-127	CD59 molecule (CD59 blood group)	Homo sapiens	310-315
8629477-7	1995	Maximal oxygen uptake increased progressively from 62.9 +/- 5.8 ml.kg-1.min-1 two weeks prior to taper, to a significantly higher level 68.9 +/- 4.2 ml.kg-1.min-1 during the final week of Taper 2 (p < or = 0.5).	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
8629477-7	1995	Maximal oxygen uptake increased progressively from 62.9 +/- 5.8 ml.kg-1.min-1 two weeks prior to taper, to a significantly higher level 68.9 +/- 4.2 ml.kg-1.min-1 during the final week of Taper 2 (p < or = 0.5).	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
7832302-8	1995	RESULTS: Halothane anesthesia significantly reduced the slope of the response of expiratory minute ventilation to carbon dioxide (from 2.88 +/- 0.73 (mean +/- SE) to 2.01 +/- 0.45 l.min-1.mmHg-1).	Halothane	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
7832302-8	1995	RESULTS: Halothane anesthesia significantly reduced the slope of the response of expiratory minute ventilation to carbon dioxide (from 2.88 +/- 0.73 (mean +/- SE) to 2.01 +/- 0.45 l.min-1.mmHg-1).	Carbon Dioxide	114-128	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
7486299-2	1995	During induction, whereas the basal heart rate was at 30-35 b.min-1, occurred an episode of bidirectional ventricular tachycardia probably induced by the administration of pancuronium.	Pancuronium	172-183	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
7766735-5	1995	In the premature newborns, ketone body turnover rates (3.2 +/- 0.2 mumol kg-1 min-1) were 74% that of fed newborns at term (4.3 +/- 0.3 mumol kg-1 min-1, p < 0.05), and 18% that of normal newborns during a brief fast (17.3 +/- 1.3 mumol kg-1 min-1, p < 0.01).	Ketones	27-33	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
7497577-6	1995	The mean area under the concentration-time curve (AUC0-->infinity) determined for ultrafiltrable platinum derived from SKI 2053R, as an active component, was 7.72 +/- 2.74 micrograms h ml-1 (mean +/- SD), with an initial half-life of 0.37 +/- 0.20 h, a terminal half-life of 2.19 +/- 0.93 h, a total clearance of 16.83 +/- 4.76 ml min-1 kg-1, and a steady-state volume of distribution of 1.57 +/- 0.30 l/kg.	Platinum	100-108	CD59 molecule (CD59 blood group)	Homo sapiens	334-344
7704991-8	1995	Edrophonium (0.5 mumol/min intra-arterially) alone produced no change in forearm blood flow but increased blood flow responses to acetylcholine (P < 0.01), causing an approximately 10-fold reduction in the dose required to increase plateau blood flow by 10 ml min-1 100 ml-1.	Edrophonium	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	263-268
7712690-3	1995	Peak pulmonary oxygen uptake (VO2) during maximal AE in normoxia and hypoxia was 2.25 +/- 0.15 and 2.18 +/- 0.14 l min-1, respectively (P < 0.05).	Oxygen	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
7712708-8	1995	Following insulin, the suppression of glycerol appearance in the circulation measured isotopically was significantly less complete in the relatives compared with controls (mean change +/- SEM: + 0.06 +/- 0.21 vs - 0.51 +/- 0.16 mumol kg-1 min-1, p < 0.05).	Glycerol	38-46	CD59 molecule (CD59 blood group)	Homo sapiens	239-244
7543386-0	1995	Dinucleotide repeat polymorphism at the human CD59 locus.	Dinucleoside Phosphates	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	46-50
7589031-8	1995	The noncompartmental means of the CL/f, terminal-phase half-life, and V/f of zileuton were approximately 545 ml min-1, 1.4 h, and 64.3 1, respectively.	Fluorine	28-29	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
7589031-8	1995	The noncompartmental means of the CL/f, terminal-phase half-life, and V/f of zileuton were approximately 545 ml min-1, 1.4 h, and 64.3 1, respectively.	zileuton	77-85	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
7589031-9	1995	The estimate of population typical values of the CL/f for a 70-kg person (540 ml min-1) and V/f for a 70-kg person (64.8 1) from the NONMEM analysis were in agreement with the noncompartmental estimates.	Fluorine	14-15	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
7729444-1	1995	Adrenaline infusion of 0.1 microgram.kg-1.min-1 in healthy volunteers results in an increase of hepatic glucose production, an increase of the absolute number of occupied beta-adrenoceptors and specific changes in metabolism.	Epinephrine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
7729444-6	1995	After 90 min of cycling the rate of appearance of glucose increased significantly from means of 2.0 (SD 0.2) to 2.65 (SD 0.50) mg.kg-1.min-1 with unchanged blood concentrations of glucose and lactate.	Glucose	50-57	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
7729444-7	1995	The flux of the amino acids alanine and leucine decreased significantly from means of 0.91 (SD 0.21) to 0.62 (SD 0.14) mg.kg-1.min-1 and from 0.40 (SD 0.05) to 0.32 (SD 0.04) mg.kg-1.min-1, respectively.	Alanine	28-35	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
7729444-7	1995	The flux of the amino acids alanine and leucine decreased significantly from means of 0.91 (SD 0.21) to 0.62 (SD 0.14) mg.kg-1.min-1 and from 0.40 (SD 0.05) to 0.32 (SD 0.04) mg.kg-1.min-1, respectively.	Alanine	28-35	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
7729444-7	1995	The flux of the amino acids alanine and leucine decreased significantly from means of 0.91 (SD 0.21) to 0.62 (SD 0.14) mg.kg-1.min-1 and from 0.40 (SD 0.05) to 0.32 (SD 0.04) mg.kg-1.min-1, respectively.	Leucine	40-47	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
7729444-7	1995	The flux of the amino acids alanine and leucine decreased significantly from means of 0.91 (SD 0.21) to 0.62 (SD 0.14) mg.kg-1.min-1 and from 0.40 (SD 0.05) to 0.32 (SD 0.04) mg.kg-1.min-1, respectively.	Leucine	40-47	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
7768243-2	1995	Physical exercise (10 min on a cycle ergometer at a heart rate of 150 beats.min-1) induced a significant increase in total leucocyte, lymphocyte and neutrophil concentrations in active subjects; serum iron and ferritin concentrations were lower in active compared to inactive subjects.	Iron	201-205	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
7768255-8	1995	This was the result of a significant decrease in the plasma clearance of diflunisal from 5.8 (control) to 3.4 ml.min-1 (probenecid co-administration).	Diflunisal	73-83	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
7768255-8	1995	This was the result of a significant decrease in the plasma clearance of diflunisal from 5.8 (control) to 3.4 ml.min-1 (probenecid co-administration).	Probenecid	120-130	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
8582465-6	1995	Compared to the placebo values, resting heart rate was significantly decreased by an average of 10 beats.min-1 by 5 mg metoprolol, whereas it was not altered by the combination regimen.	Metoprolol	119-129	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
8983921-6	1995	At rest the results revealed that only oxygen uptake was significantly lower (P < 0.05) in the morning compared to that observed in the evening [2.9 (SD 0.4) compared to 3.5 (SD 0.5) ml O2.kg-1.min-1, respectively].	Oxygen	39-45	CD59 molecule (CD59 blood group)	Homo sapiens	197-202
7748624-5	1995	The fractional metabolite clearance of paracetamol to glutathione-derived conjugates (0.28 ml min-1 kg-1) in our patient was > 30% lower than in normal females.	Acetaminophen	39-50	CD59 molecule (CD59 blood group)	Homo sapiens	94-104
7748624-5	1995	The fractional metabolite clearance of paracetamol to glutathione-derived conjugates (0.28 ml min-1 kg-1) in our patient was > 30% lower than in normal females.	Glutathione	54-65	CD59 molecule (CD59 blood group)	Homo sapiens	94-104
7798329-2	1995	The tricarboxylic acid (TCA) cycle rate was 0.73 +/- 0.19 mumol min-1 g-1 (mean +/- SD; n = 4).	Tricarboxylic Acids	4-22	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
7798329-2	1995	The tricarboxylic acid (TCA) cycle rate was 0.73 +/- 0.19 mumol min-1 g-1 (mean +/- SD; n = 4).	Tricarboxylic Acids	24-27	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
7798329-4	1995	The rate of alpha-ketoglutarate/glutamate exchange was 57 +/- 26 mumol min-1 g-1 (n = 3), which is much greater than the TCA cycle rate; the high rate indicates that alpha-ketoglutarate and glutamate are in rapid exchange and can be treated as a single combined kinetic pool.	Ketoglutaric Acids	12-31	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
7798329-4	1995	The rate of alpha-ketoglutarate/glutamate exchange was 57 +/- 26 mumol min-1 g-1 (n = 3), which is much greater than the TCA cycle rate; the high rate indicates that alpha-ketoglutarate and glutamate are in rapid exchange and can be treated as a single combined kinetic pool.	Glutamic Acid	32-41	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
7798329-4	1995	The rate of alpha-ketoglutarate/glutamate exchange was 57 +/- 26 mumol min-1 g-1 (n = 3), which is much greater than the TCA cycle rate; the high rate indicates that alpha-ketoglutarate and glutamate are in rapid exchange and can be treated as a single combined kinetic pool.	Ketoglutaric Acids	166-185	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
7798329-5	1995	The rate of synthesis of glutamine from glutamate was 0.47 mumol min-1 g-1 (n = 4), with 95% confidence limits of 0.139 and 3.094 mumol min-1 g-1; individual uncertainties were biased heavily toward high synthesis rates.	Glutamine	25-34	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
7798329-5	1995	The rate of synthesis of glutamine from glutamate was 0.47 mumol min-1 g-1 (n = 4), with 95% confidence limits of 0.139 and 3.094 mumol min-1 g-1; individual uncertainties were biased heavily toward high synthesis rates.	Glutamine	25-34	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
7798329-6	1995	From the TCA cycle rate the brain oxygen consumption was estimated to be 2.14 +/- 0.48 mumol min-1 g-1 (5.07 +/- 1.14 ml 100 g-1 min-1; n = 4), and the rate of brain glucose consumption was calculated to be 0.37 +/- 0.08 mumol min-1 g-1 (n = 4).	Tricarboxylic Acids	9-12	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
7798329-6	1995	From the TCA cycle rate the brain oxygen consumption was estimated to be 2.14 +/- 0.48 mumol min-1 g-1 (5.07 +/- 1.14 ml 100 g-1 min-1; n = 4), and the rate of brain glucose consumption was calculated to be 0.37 +/- 0.08 mumol min-1 g-1 (n = 4).	Oxygen	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
7798329-6	1995	From the TCA cycle rate the brain oxygen consumption was estimated to be 2.14 +/- 0.48 mumol min-1 g-1 (5.07 +/- 1.14 ml 100 g-1 min-1; n = 4), and the rate of brain glucose consumption was calculated to be 0.37 +/- 0.08 mumol min-1 g-1 (n = 4).	Oxygen	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
7798329-6	1995	From the TCA cycle rate the brain oxygen consumption was estimated to be 2.14 +/- 0.48 mumol min-1 g-1 (5.07 +/- 1.14 ml 100 g-1 min-1; n = 4), and the rate of brain glucose consumption was calculated to be 0.37 +/- 0.08 mumol min-1 g-1 (n = 4).	Oxygen	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
7814625-3	1995	We found that glutamine appearance in plasma exceeded that of alanine (5.76 +/- 0.26 vs. 4.40 +/- 0.33 mumol.kg-1.min-1, P < 0.001), while alanine clearance exceeded glutamine clearance (14.7 +/- 1.3 vs. 9.3 +/- 0.8 ml.kg-1.min-1, P < 0.001).	Glutamine	14-23	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
7814625-3	1995	We found that glutamine appearance in plasma exceeded that of alanine (5.76 +/- 0.26 vs. 4.40 +/- 0.33 mumol.kg-1.min-1, P < 0.001), while alanine clearance exceeded glutamine clearance (14.7 +/- 1.3 vs. 9.3 +/- 0.8 ml.kg-1.min-1, P < 0.001).	Glutamine	14-23	CD59 molecule (CD59 blood group)	Homo sapiens	227-232
7814625-4	1995	Glutamine appearance in plasma directly due to its release from protein was more than double that of alanine (2.45 +/- 0.25 vs. 1.16 +/- 0.12 mumol.kg-1.min-1, P < 0.001).	Glutamine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
7830033-7	1995	Enalapril reduced albumin excretion from 1090 +/- 281 micrograms min-1 to 742 +/- 246 micrograms min-1 (P < 0.01) and total protein excretion from 2.0 +/- 0.4 g per 24 h to 1.3 +/- 0.4 per 24 h whereas doxazosin was without effect.	Enalapril	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
7830033-7	1995	Enalapril reduced albumin excretion from 1090 +/- 281 micrograms min-1 to 742 +/- 246 micrograms min-1 (P < 0.01) and total protein excretion from 2.0 +/- 0.4 g per 24 h to 1.3 +/- 0.4 per 24 h whereas doxazosin was without effect.	Enalapril	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
7699829-2	1995	In control group, infusion of PGE1 at a rate of 20 ng.kg-1.min-1 decreased pulmonary arterial pressure significantly, but not in elderly patients even at a rate of 50 ng.kg-1.min-1.	Alprostadil	30-34	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
7699829-2	1995	In control group, infusion of PGE1 at a rate of 20 ng.kg-1.min-1 decreased pulmonary arterial pressure significantly, but not in elderly patients even at a rate of 50 ng.kg-1.min-1.	Alprostadil	30-34	CD59 molecule (CD59 blood group)	Homo sapiens	175-180
7489473-9	1995	Lignocaine infusions in the dosage range of 20 to 40 micrograms.kg-1.min-1 rarely produce toxic levels, and monitoring of lignocaine levels every 12 h is an effective method of screening for toxicity.	Lidocaine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
7571892-4	1995	For a normal systemic oxygen consumption of 120 ml min-1 m-2 a critical degree of hemodilution is achieved at an hematocrit of 14% and an hemoglobin content of 4.7 g dl-1, respectively.	Oxygen	22-28	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
7571892-6	1995	An increase of systemic oxygen consumption by a factor of three (460 ml min-1 m-2), which might be typical for a patient during the postoperative recovery phase, increases the critical hematocrit to 21%.	Oxygen	24-30	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
7527603-3	1994	Human DAF and CD59 were released from the surface of transfected rat cells by phosphatidylinositol phospholipase C, demonstrating that the two molecules were linked to the cell membrane by means of a glycolipid anchor.	Phosphatidylinositols	78-98	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
7527603-3	1994	Human DAF and CD59 were released from the surface of transfected rat cells by phosphatidylinositol phospholipase C, demonstrating that the two molecules were linked to the cell membrane by means of a glycolipid anchor.	Glycolipids	200-210	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
7889023-7	1994	The renal clearance value for morphine was 162 ml.min-1 and for the glucuronides 81 ml.min-1.	Morphine	30-38	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
7889023-7	1994	The renal clearance value for morphine was 162 ml.min-1 and for the glucuronides 81 ml.min-1.	Glucuronides	68-80	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
7810637-1	1994	Whole body lipid kinetics were evaluated during basal resting conditions, 4 h of treadmill exercise eliciting an oxygen uptake of 20 ml.kg-1.min-1, and 1 h of recovery in five untrained and five endurance-trained men.	Oxygen	113-119	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
7810637-4	1994	However, mean triglyceride oxidation was greater during exercise in the trained than in the untrained group (7.51 +/- 0.26 and 5.67 +/- 0.51 mumol.kg-1.min-1, respectively; P < 0.001).	Triglycerides	14-26	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
7892983-5	1994	Oxygen was administered through nasal cannulae at a flow of 2 l.min-1.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
8582465-7	1995	During exercise, however, both the combination regimen and metoprolol alone showed a significant negative chronotropic effect, decreasing peak exercise heart rate by an average of 14 and 21 beats.min-1, respectively.	Metoprolol	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	196-201
8641327-8	1995	The total body clearance of furosemide in the volunteers was 138 ml x min(-1) and this was much lower in the CAPD patients (61.9 ml x min(-1)) in whom the renal clearance was negligible.	Furosemide	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	70-76
8641327-8	1995	The total body clearance of furosemide in the volunteers was 138 ml x min(-1) and this was much lower in the CAPD patients (61.9 ml x min(-1)) in whom the renal clearance was negligible.	Furosemide	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	134-140
7528012-10	1994	An N-glycosylation site was identified at Asn-16 and a putative glycosylphosphatidylinositol anchor addition site at Asn-79, indicating that the mature processed protein was two residues longer than human CD59.	Glycosylphosphatidylinositols	64-92	CD59 molecule (CD59 blood group)	Homo sapiens	205-209
7524752-2	1994	Affected blood cells in PNH lack glycosylphosphatidylinositol (GPI)-anchored membrane proteins such as decay-accelerating factor (DAF) and CD59.	Glycosylphosphatidylinositols	63-66	CD59 molecule (CD59 blood group)	Homo sapiens	139-143
7923439-6	1994	The rate constant for the disappearance of the PM signal in incubations with glutathione was 6.2 x 10(-3) min-1, and was 5.4 x 10(-3) min-1 in incubations without glutathione, indicating that the rate-limiting step in both reactions in the formation of aziridinium ions.	Glutathione	77-88	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
7874862-15	1994	In response to the clamp, palmitate turnover fell to 0.42 +/- 0.05, 0.69 +/- 0.08 and 1.28 +/- 0.45 mumol min-1 kg-1 body weight.	Palmitates	26-35	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
7874862-16	1994	Plasma palmitate oxidation was 0.58 +/- 0.04, 0.75 +/- 0.06 and 1.13 +/- 0.11 mumol min-1 kg-1 body weight basally, and fell to 0.16 +/- 0.02, 0.28 +/- 0.04 and 0.43 +/- 0.13 mumol min-1 kg-1 body weight by the end of the clamp.	Palmitates	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
7874862-16	1994	Plasma palmitate oxidation was 0.58 +/- 0.04, 0.75 +/- 0.06 and 1.13 +/- 0.11 mumol min-1 kg-1 body weight basally, and fell to 0.16 +/- 0.02, 0.28 +/- 0.04 and 0.43 +/- 0.13 mumol min-1 kg-1 body weight by the end of the clamp.	Palmitates	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
7696378-9	1994	Respective values for (S)-propranolol after single isomer administration (20 mg) were 86 (36) and 57 (25) ml min-1 kg-1 in single dose and steady state situations.	Propranolol	22-37	CD59 molecule (CD59 blood group)	Homo sapiens	109-119
7978442-5	1994	Nicardipine significantly decreased the vecuronium requirement in a dose-dependent manner, i.e., the vecuronium doses were 0.70 +/- 0.03, 0.55 +/- 0.04, 0.42 +/- 0.04, and 0.37 +/- 0.05 micrograms.kg-1.min-1 at nicardipine doses of 0, 1, 2, and 3 micrograms.kg-1.min-1, respectively.	Nicardipine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	202-207
7978442-5	1994	Nicardipine significantly decreased the vecuronium requirement in a dose-dependent manner, i.e., the vecuronium doses were 0.70 +/- 0.03, 0.55 +/- 0.04, 0.42 +/- 0.04, and 0.37 +/- 0.05 micrograms.kg-1.min-1 at nicardipine doses of 0, 1, 2, and 3 micrograms.kg-1.min-1, respectively.	Nicardipine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	263-268
7992901-10	1994	RESULTS: In the control and intravenous lidocaine groups, an increase in isoflurane concentration from 2% to 3% significantly increased systolic blood pressure (peak changes of 16 +/- 5 and 15 +/- 6 mmHg, respectively) and heart rate (peak changes of 23 +/- 3 and 13 +/- 4 beats.min-1, respectively).	Lidocaine	40-49	CD59 molecule (CD59 blood group)	Homo sapiens	279-284
7992901-10	1994	RESULTS: In the control and intravenous lidocaine groups, an increase in isoflurane concentration from 2% to 3% significantly increased systolic blood pressure (peak changes of 16 +/- 5 and 15 +/- 6 mmHg, respectively) and heart rate (peak changes of 23 +/- 3 and 13 +/- 4 beats.min-1, respectively).	Isoflurane	73-83	CD59 molecule (CD59 blood group)	Homo sapiens	279-284
7992901-12	1994	Blood pressure and heart rate responses to a change to 3% isoflurane were significantly blunted in the groups receiving clonidine (peak changes of 4 +/- 4 mmHg and 8 +/- 3 beats.min-1, respectively) or nasal lidocaine (peak changes of 2 +/- 1 mmHg and 4 +/- 2 beats.min-1, respectively) compared with the control group.	Isoflurane	58-68	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
7992901-12	1994	Blood pressure and heart rate responses to a change to 3% isoflurane were significantly blunted in the groups receiving clonidine (peak changes of 4 +/- 4 mmHg and 8 +/- 3 beats.min-1, respectively) or nasal lidocaine (peak changes of 2 +/- 1 mmHg and 4 +/- 2 beats.min-1, respectively) compared with the control group.	Isoflurane	58-68	CD59 molecule (CD59 blood group)	Homo sapiens	266-271
7992901-12	1994	Blood pressure and heart rate responses to a change to 3% isoflurane were significantly blunted in the groups receiving clonidine (peak changes of 4 +/- 4 mmHg and 8 +/- 3 beats.min-1, respectively) or nasal lidocaine (peak changes of 2 +/- 1 mmHg and 4 +/- 2 beats.min-1, respectively) compared with the control group.	Clonidine	120-129	CD59 molecule (CD59 blood group)	Homo sapiens	266-271
7992901-12	1994	Blood pressure and heart rate responses to a change to 3% isoflurane were significantly blunted in the groups receiving clonidine (peak changes of 4 +/- 4 mmHg and 8 +/- 3 beats.min-1, respectively) or nasal lidocaine (peak changes of 2 +/- 1 mmHg and 4 +/- 2 beats.min-1, respectively) compared with the control group.	nasal lidocaine	202-217	CD59 molecule (CD59 blood group)	Homo sapiens	266-271
7704038-3	1994	The kinetic parameters for the N-demethylation in the EM group were: Km 1, 19.4 +/- 0.4 microM; Vmax 1, 0.27 +/- 0.04 nmol min-1 per mg protein; Km 2, 346 +/- 34 microM; Vmax2, 1.82 +/- 0.63 nmol min-1 per mg protein (n = 3, mean +/- SD).	Nitrogen	31-32	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
7704038-3	1994	The kinetic parameters for the N-demethylation in the EM group were: Km 1, 19.4 +/- 0.4 microM; Vmax 1, 0.27 +/- 0.04 nmol min-1 per mg protein; Km 2, 346 +/- 34 microM; Vmax2, 1.82 +/- 0.63 nmol min-1 per mg protein (n = 3, mean +/- SD).	Nitrogen	31-32	CD59 molecule (CD59 blood group)	Homo sapiens	196-201
7899232-8	1994	The rate of hydrolysis of menthol-beta-D-glucuronide was 6.26 +/- 2.88 nmol min-1 mg-1 and 2.34 +/- 1.22 nmol min-1 mg-1 in luminal contents of the rat cecum and colon, respectively.	menthol-beta-d-glucuronide	26-52	CD59 molecule (CD59 blood group)	Homo sapiens	76-86
7899232-8	1994	The rate of hydrolysis of menthol-beta-D-glucuronide was 6.26 +/- 2.88 nmol min-1 mg-1 and 2.34 +/- 1.22 nmol min-1 mg-1 in luminal contents of the rat cecum and colon, respectively.	menthol-beta-d-glucuronide	26-52	CD59 molecule (CD59 blood group)	Homo sapiens	110-120
7899232-9	1994	The hydrolysis rate of menthol-beta-D-glucuronide was lower in human stool samples (0.52 +/- 0.46 nmol min-1 mg-1).	menthol-beta-d-glucuronide	23-49	CD59 molecule (CD59 blood group)	Homo sapiens	103-113
7872005-9	1994	Oxygen uptake, measured during the exercise and recovery periods of sprints 6-9, was lower in the hypoxic condition [3.03 (0.2) vs. 3.19 (0.2) 1 min-1, P < 0.05].	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
7977706-4	1994	The rate constant of PGI2 synthesis from PGH2 was 0.13 min-1.	Epoprostenol	21-25	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
7977706-4	1994	The rate constant of PGI2 synthesis from PGH2 was 0.13 min-1.	Prostaglandin H2	41-45	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
7826789-2	1994	Mivacurium 15 micrograms kg-1 min-1 was infused for 10 min (total dose 0.15 mg kg-1) and the plasma concentration of the three isomers measured at regular intervals for 190 min.	Mivacurium	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
7893584-8	1994	Metoprolol was given together with the dose of isoprenaline which increased heart rate by 25 beats min-1.	Metoprolol	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
7893584-8	1994	Metoprolol was given together with the dose of isoprenaline which increased heart rate by 25 beats min-1.	Isoproterenol	47-59	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
7531114-7	1994	RESULTS: In the healthy controls noradrenaline (60, 120, and 240 pmol.min-1) and L-NMMA (1, 2, and 4 mumol.min-1) produced similar reductions in resting forearm blood flow.	Norepinephrine	33-46	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
7531114-7	1994	RESULTS: In the healthy controls noradrenaline (60, 120, and 240 pmol.min-1) and L-NMMA (1, 2, and 4 mumol.min-1) produced similar reductions in resting forearm blood flow.	omega-N-Methylarginine	81-87	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
7851351-8	1994	Oxygen uptake decreased in both groups after induction (sufentanil 289 +/- 29 to 184 +/- 21 ml min-1; fentanyl 318 +/- 32 to 216 +/- 32 ml min-1) and remained low with sufentanil until flumazenil was given.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
7851351-8	1994	Oxygen uptake decreased in both groups after induction (sufentanil 289 +/- 29 to 184 +/- 21 ml min-1; fentanyl 318 +/- 32 to 216 +/- 32 ml min-1) and remained low with sufentanil until flumazenil was given.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
7527225-4	1994	Using these conditions, and in the presence of 10 mmol dm-3 sodium taurocholate (TC), the derived Michaelis-Menten parameters Vmax and Km were 57.5 mumol min-1 mg-1 and 5.53 mmol dm-3, respectively.	dm-3 sodium taurocholate	55-79	CD59 molecule (CD59 blood group)	Homo sapiens	154-170
7527225-4	1994	Using these conditions, and in the presence of 10 mmol dm-3 sodium taurocholate (TC), the derived Michaelis-Menten parameters Vmax and Km were 57.5 mumol min-1 mg-1 and 5.53 mmol dm-3, respectively.	Taurocholic Acid	81-83	CD59 molecule (CD59 blood group)	Homo sapiens	154-170
7527225-4	1994	Using these conditions, and in the presence of 10 mmol dm-3 sodium taurocholate (TC), the derived Michaelis-Menten parameters Vmax and Km were 57.5 mumol min-1 mg-1 and 5.53 mmol dm-3, respectively.	Dm-3	55-59	CD59 molecule (CD59 blood group)	Homo sapiens	154-170
7859918-5	1994	With cholesterol sulfate as substrate, the turnover number of cytochrome P-450scc in cultured cells was 2.8 min-1 and was not significantly different to the turnover number of the cytochrome for placental mitochondria, where cholesterol is known to be saturating.	cholesteryl sulfate	5-24	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
7523406-7	1994	These experiments revealed a 17-kDa fragment (starting at C9 residue Thr-320) that retained affinity for CD59, suggesting the possibility for localizing the CD59 binding site by mapping with small C9-derived peptides.	Threonine	69-72	CD59 molecule (CD59 blood group)	Homo sapiens	105-109
7523406-7	1994	These experiments revealed a 17-kDa fragment (starting at C9 residue Thr-320) that retained affinity for CD59, suggesting the possibility for localizing the CD59 binding site by mapping with small C9-derived peptides.	Threonine	69-72	CD59 molecule (CD59 blood group)	Homo sapiens	157-161
7522635-3	1994	Specifically, somatic mutations in the phosphatidylinositol glycan class A gene result in the ability of blood cells to anchor complement-regulatory proteins (CD59 and DAF) to the cell surface via glycosyl phosphatidylinositol (GPI).	Phosphatidylinositols	39-59	CD59 molecule (CD59 blood group)	Homo sapiens	159-163
7522635-3	1994	Specifically, somatic mutations in the phosphatidylinositol glycan class A gene result in the ability of blood cells to anchor complement-regulatory proteins (CD59 and DAF) to the cell surface via glycosyl phosphatidylinositol (GPI).	Glycosylphosphatidylinositols	197-226	CD59 molecule (CD59 blood group)	Homo sapiens	159-163
7522635-3	1994	Specifically, somatic mutations in the phosphatidylinositol glycan class A gene result in the ability of blood cells to anchor complement-regulatory proteins (CD59 and DAF) to the cell surface via glycosyl phosphatidylinositol (GPI).	Glycosylphosphatidylinositols	228-231	CD59 molecule (CD59 blood group)	Homo sapiens	159-163
7925994-1	1994	Exogenous sphingomyelin, radiolabelled at the sphingosine moiety, was administered to primary cultures of cerebellar granule cells and astrocytes for different pulse times (20 min-2 h) and the fate of the radioactivity was followed.	Sphingomyelins	10-23	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
7802176-9	1994	With the laryngeal mask and the tracheal tube, mean (SE) minute ventilation was 9.4(0.9)l.min-1 and 8.1(0.9)l.min-1, respectively for end-tidal carbon dioxide concentrations between 3.6 and 4.1%.	Carbon Dioxide	144-158	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
7849237-4	1994	On the other hand, after 1.0 mg kg-1 IV administration, t1/2 lambda zeta was 3.04 +/- 0.11 h, CLtot was 15.9 +/- 0.2 mL min-1, and Vd,ss was 6950 +/- 600 mL kg-1.	cltot	94-99	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
7530473-7	1994	Co-infusion of L-NMMA (2 mumol min-1 and 4 mumol min-1) with bradykinin (100 pmol min-1) for 6 min produced respectively a 9 +/- 14% and 42 +/- 14% inhibition (compared with L-NMMA vehicle) in the response to bradykinin.	omega-N-Methylarginine	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	31-42
7530473-7	1994	Co-infusion of L-NMMA (2 mumol min-1 and 4 mumol min-1) with bradykinin (100 pmol min-1) for 6 min produced respectively a 9 +/- 14% and 42 +/- 14% inhibition (compared with L-NMMA vehicle) in the response to bradykinin.	omega-N-Methylarginine	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
7530473-7	1994	Co-infusion of L-NMMA (2 mumol min-1 and 4 mumol min-1) with bradykinin (100 pmol min-1) for 6 min produced respectively a 9 +/- 14% and 42 +/- 14% inhibition (compared with L-NMMA vehicle) in the response to bradykinin.	omega-N-Methylarginine	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7530473-7	1994	Co-infusion of L-NMMA (2 mumol min-1 and 4 mumol min-1) with bradykinin (100 pmol min-1) for 6 min produced respectively a 9 +/- 14% and 42 +/- 14% inhibition (compared with L-NMMA vehicle) in the response to bradykinin.	omega-N-Methylarginine	174-180	CD59 molecule (CD59 blood group)	Homo sapiens	31-42
7530473-7	1994	Co-infusion of L-NMMA (2 mumol min-1 and 4 mumol min-1) with bradykinin (100 pmol min-1) for 6 min produced respectively a 9 +/- 14% and 42 +/- 14% inhibition (compared with L-NMMA vehicle) in the response to bradykinin.	omega-N-Methylarginine	174-180	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7530473-11	1994	Co-infusion of L-NMMA (2 mumol min-1 and 4 mumol min-1) with substance P (1 pmol min-1) for 6 min produced respectively a 27 +/- 8% and 70 +/- 13% inhibition (compared with L-NMMA vehicle) in the response to substance P.	omega-N-Methylarginine	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	31-42
7530473-11	1994	Co-infusion of L-NMMA (2 mumol min-1 and 4 mumol min-1) with substance P (1 pmol min-1) for 6 min produced respectively a 27 +/- 8% and 70 +/- 13% inhibition (compared with L-NMMA vehicle) in the response to substance P.	omega-N-Methylarginine	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
7530473-11	1994	Co-infusion of L-NMMA (2 mumol min-1 and 4 mumol min-1) with substance P (1 pmol min-1) for 6 min produced respectively a 27 +/- 8% and 70 +/- 13% inhibition (compared with L-NMMA vehicle) in the response to substance P.	omega-N-Methylarginine	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7530473-11	1994	Co-infusion of L-NMMA (2 mumol min-1 and 4 mumol min-1) with substance P (1 pmol min-1) for 6 min produced respectively a 27 +/- 8% and 70 +/- 13% inhibition (compared with L-NMMA vehicle) in the response to substance P.	omega-N-Methylarginine	173-179	CD59 molecule (CD59 blood group)	Homo sapiens	31-42
7530473-11	1994	Co-infusion of L-NMMA (2 mumol min-1 and 4 mumol min-1) with substance P (1 pmol min-1) for 6 min produced respectively a 27 +/- 8% and 70 +/- 13% inhibition (compared with L-NMMA vehicle) in the response to substance P.	omega-N-Methylarginine	173-179	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7833219-8	1994	L-NMMA</compound-id> (4 mumol min-1; 5 min) alone reduced resting forearm blood flow by 44% (P &lt; 0.01; n = 6) confirming that nitric oxide plays an important role in regulating vascular tone.	Nitric Oxide	129-141	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
7833219-10	1994	Bradykinin (10 and 100 pmol min-1; 3 min each dose) and GTN (2 and 5 nmol min-1; 3 min each dose) increased forearm blood flow in a dose-dependent manner (percentage changes 171 +/- 17% and 398 +/- 35%, and 176 +/- 21% and 268 +/- 42%, respectively; n = 6).	Nitroglycerin	56-59	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
7919328-7	1994	However, busulfan clearance normalized to body weight was significantly higher in children (3.62 +/- 0.78 mL.min-1.kg-1) than that in adults (2.49 +/- 0.52 mL.min-1.kg-1).	Busulfan	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
7999486-8	1994	In this study, an infusion of phenylephrine 10 micrograms min-1 with bolus doses of 20 micrograms was shown to be significantly less effective in maintaining systolic arterial pressure within 20% limits of baseline compared with an infusion of ephedrine 1 or 2 mg min-1 with bolus doses of 6 mg.	Phenylephrine	30-43	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
7999486-8	1994	In this study, an infusion of phenylephrine 10 micrograms min-1 with bolus doses of 20 micrograms was shown to be significantly less effective in maintaining systolic arterial pressure within 20% limits of baseline compared with an infusion of ephedrine 1 or 2 mg min-1 with bolus doses of 6 mg.	Phenylephrine	30-43	CD59 molecule (CD59 blood group)	Homo sapiens	264-269
7999486-8	1994	In this study, an infusion of phenylephrine 10 micrograms min-1 with bolus doses of 20 micrograms was shown to be significantly less effective in maintaining systolic arterial pressure within 20% limits of baseline compared with an infusion of ephedrine 1 or 2 mg min-1 with bolus doses of 6 mg.	Ephedrine	244-253	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
7821319-1	1994	Forty-five patients with recent-onset sustained atrial tachyarrhythmia (mean heart rate at entry; 140.0 +/- 3.5 beats.min-1) associated with various cardiovascular diseases were treated by oral amiodarone, given as a single loading dose of 25.7 +/- 0.9 mg.kg-1 body weight.	Amiodarone	194-204	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
7821319-4	1994	A similar population of 27 patients (mean heart rate at entry; 140 +/- 3 beats.min-1) was treated by intravenous amiodarone, given as a bolus infusion of 3-5 mg.kg-1 over 30 min (mean; 4.1 +/- 0.2 mg.kg-1), followed by a continuous infusion of 10-15 mg.kg-1 for 24 h (mean; 11.1 +/- 0.7 mg.kg-1).	Amiodarone	113-123	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
7861719-6	1994	Iothalamate clearance declined at an average rate of -3.1 ml/min/1.73 m2 per year (95% CI -5.8, -0.3) during the period of cyclosporin treatment.	Iothalamic Acid	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
7821712-5	1994	With cholesterol sulfate as substrate, the turnover number of cytochrome P-450scc in cultured cells was 2.8 min-1 and was not significantly different to the turnover number of the cytochrome for placental mitochondria, where cholesterol is known to be saturating.	cholesteryl sulfate	5-24	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
7809577-8	1994	We found, that indomethacin given intravenously (protocol B groups 2-3-4) significantly elevated circulating levels of ET from 2.1 to 3.9fmol ml-1 plasma (p &lt; 0.00005) and decreased CBF from 60.5 to 39.5 ml 100g-1 brain tissue min-1 (p &lt; 0.00005) compared to baseline values.	Indomethacin	15-27	CD59 molecule (CD59 blood group)	Homo sapiens	230-235
7727373-6	1994	When the reaction was conducted in the presence of CO, H2, or titanium(III), or in the absence of any electron donor, the rate of demethylation of syringic acid at pH 7.2 was approximately 15 nmol min-1 mg-1.	Carbon Monoxide	51-53	CD59 molecule (CD59 blood group)	Homo sapiens	197-207
7727373-6	1994	When the reaction was conducted in the presence of CO, H2, or titanium(III), or in the absence of any electron donor, the rate of demethylation of syringic acid at pH 7.2 was approximately 15 nmol min-1 mg-1.	Hydrogen	55-57	CD59 molecule (CD59 blood group)	Homo sapiens	197-207
7727373-6	1994	When the reaction was conducted in the presence of CO, H2, or titanium(III), or in the absence of any electron donor, the rate of demethylation of syringic acid at pH 7.2 was approximately 15 nmol min-1 mg-1.	Titanium(III)	62-75	CD59 molecule (CD59 blood group)	Homo sapiens	197-207
7521361-10	1994	Finally, the ability of CD59 to enhance CD58-dependent T cell responses was shown to be dependent on N-glycosylation of CD59 at amino acid Asn18.	Nitrogen	101-102	CD59 molecule (CD59 blood group)	Homo sapiens	24-28
7521361-10	1994	Finally, the ability of CD59 to enhance CD58-dependent T cell responses was shown to be dependent on N-glycosylation of CD59 at amino acid Asn18.	Nitrogen	101-102	CD59 molecule (CD59 blood group)	Homo sapiens	120-124
7522441-1	1994	The major glycolipid co-immunopurifying with the glycosylphosphatidylinositol-anchored leucocyte surface glycoprotein CD59 from detergent lysates of human T cell lines HPB ALL, Jurkat and myeloid line HL-60 was identified as the glycosphingolipid GM3.	Glycolipids	10-20	CD59 molecule (CD59 blood group)	Homo sapiens	118-122
7522441-1	1994	The major glycolipid co-immunopurifying with the glycosylphosphatidylinositol-anchored leucocyte surface glycoprotein CD59 from detergent lysates of human T cell lines HPB ALL, Jurkat and myeloid line HL-60 was identified as the glycosphingolipid GM3.	Glycosylphosphatidylinositols	49-77	CD59 molecule (CD59 blood group)	Homo sapiens	118-122
7522441-1	1994	The major glycolipid co-immunopurifying with the glycosylphosphatidylinositol-anchored leucocyte surface glycoprotein CD59 from detergent lysates of human T cell lines HPB ALL, Jurkat and myeloid line HL-60 was identified as the glycosphingolipid GM3.	Glycosphingolipids	229-246	CD59 molecule (CD59 blood group)	Homo sapiens	118-122
7522441-1	1994	The major glycolipid co-immunopurifying with the glycosylphosphatidylinositol-anchored leucocyte surface glycoprotein CD59 from detergent lysates of human T cell lines HPB ALL, Jurkat and myeloid line HL-60 was identified as the glycosphingolipid GM3.	gm3	247-250	CD59 molecule (CD59 blood group)	Homo sapiens	118-122
7810336-10	1994	Intravenously infused GTN (4-512 micrograms kg body wt-1 min-1) and SNP (4-64 micrograms kg body wt-1 min-1) decreased arterial pressure and elicited, via reflex sympathetic activation, a dose-dependent vasoconstriction in skeletal muscle, a decrease in Pc,v, and net transcapillary fluid absorption.	Nitroglycerin	22-25	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
7944692-4	1994	If exercise testing revealed a peak oxygen uptake of 15 mL.kg-1.min-1 or greater, the patient was offered surgical treatment.	Oxygen	36-42	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
7944692-8	1994	Five patients whose peak oxygen uptake was lower than 15 mL.kg-1.min-1 also underwent surgical intervention; there was one death.	Oxygen	25-31	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
7826820-7	1994	In separate studies L-NMMA (0.1 microgram min-1) was pre- and co-infused with nebivolol to determine whether nitric oxide (NO) mediated mechanisms were present.	omega-N-Methylarginine	20-26	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
7826820-12	1994	At doses of nebivolol producing plasma concentrations comparable with plasma levels achieved after standard oral dosing (10(-13)-10(-12) mol min-1) small (14 +/- 6% and 23 +/- 8%) but significant (P &lt; 0.05) venodilation was observed.	Nebivolol	12-21	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
7826834-2	1994	Ambulatory 24 h Holter electrocardiogram recordings showed that xamoterol decreased maximum heart rate from 140 +/- 5.1 to 107 +/- 6 beats min-1 (P &lt; 0.001) during exercise, increased minimum heart rate from 43 +/- 1.7 to 51 +/- 2.4 beats min-1 (P &lt; 0.005) at night and shortened maximum duration of sinus arrest from 3438 +/- 484 to 1767 +/- 202 ms (P &lt; 0.005) in BTS.	Xamoterol	64-73	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
7826834-2	1994	Ambulatory 24 h Holter electrocardiogram recordings showed that xamoterol decreased maximum heart rate from 140 +/- 5.1 to 107 +/- 6 beats min-1 (P &lt; 0.001) during exercise, increased minimum heart rate from 43 +/- 1.7 to 51 +/- 2.4 beats min-1 (P &lt; 0.005) at night and shortened maximum duration of sinus arrest from 3438 +/- 484 to 1767 +/- 202 ms (P &lt; 0.005) in BTS.	Xamoterol	64-73	CD59 molecule (CD59 blood group)	Homo sapiens	242-247
7820974-6	1994	The glucose-induced thermogenesis in the 120 min following the glucose load was significantly reduced by beta-adrenergic inhibition with approximately 50% from 63.9 +/- 5.8 kJ 120 min-1 (mean +/- SE) to 27.8 +/- 9.8 kJ 120 min-1 (P &lt; 0.01).	Glucose	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
7820974-6	1994	The glucose-induced thermogenesis in the 120 min following the glucose load was significantly reduced by beta-adrenergic inhibition with approximately 50% from 63.9 +/- 5.8 kJ 120 min-1 (mean +/- SE) to 27.8 +/- 9.8 kJ 120 min-1 (P &lt; 0.01).	Glucose	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	223-228
7820974-8	1994	The integrated glucose-induced forearm oxygen uptake in the period 60-120 min following the glucose load was significantly reduced after beta-adrenergic inhibition from 103 +/- 28 mumol 100 g-1 60 min-1 to 29 +/- 29 mumol 100 g-1 60 min-1 (P &lt; 0.05).	Glucose	15-22	CD59 molecule (CD59 blood group)	Homo sapiens	197-202
7820974-8	1994	The integrated glucose-induced forearm oxygen uptake in the period 60-120 min following the glucose load was significantly reduced after beta-adrenergic inhibition from 103 +/- 28 mumol 100 g-1 60 min-1 to 29 +/- 29 mumol 100 g-1 60 min-1 (P &lt; 0.05).	Glucose	15-22	CD59 molecule (CD59 blood group)	Homo sapiens	233-238
7820974-8	1994	The integrated glucose-induced forearm oxygen uptake in the period 60-120 min following the glucose load was significantly reduced after beta-adrenergic inhibition from 103 +/- 28 mumol 100 g-1 60 min-1 to 29 +/- 29 mumol 100 g-1 60 min-1 (P &lt; 0.05).	Oxygen	39-45	CD59 molecule (CD59 blood group)	Homo sapiens	197-202
7820974-8	1994	The integrated glucose-induced forearm oxygen uptake in the period 60-120 min following the glucose load was significantly reduced after beta-adrenergic inhibition from 103 +/- 28 mumol 100 g-1 60 min-1 to 29 +/- 29 mumol 100 g-1 60 min-1 (P &lt; 0.05).	Oxygen	39-45	CD59 molecule (CD59 blood group)	Homo sapiens	233-238
7820974-8	1994	The integrated glucose-induced forearm oxygen uptake in the period 60-120 min following the glucose load was significantly reduced after beta-adrenergic inhibition from 103 +/- 28 mumol 100 g-1 60 min-1 to 29 +/- 29 mumol 100 g-1 60 min-1 (P &lt; 0.05).	Glucose	92-99	CD59 molecule (CD59 blood group)	Homo sapiens	197-202
7820974-8	1994	The integrated glucose-induced forearm oxygen uptake in the period 60-120 min following the glucose load was significantly reduced after beta-adrenergic inhibition from 103 +/- 28 mumol 100 g-1 60 min-1 to 29 +/- 29 mumol 100 g-1 60 min-1 (P &lt; 0.05).	Glucose	92-99	CD59 molecule (CD59 blood group)	Homo sapiens	233-238
7859897-10	1994	Glomerular filtration rate was unchanged and renal plasma flow increased in the Captopril (557 +/- 97 and 600 +/- 112 ml min-1) versus the placebo group (574 +/- 85 and 535 ml min-1, p = 0.05).	Captopril	80-89	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
7859897-10	1994	Glomerular filtration rate was unchanged and renal plasma flow increased in the Captopril (557 +/- 97 and 600 +/- 112 ml min-1) versus the placebo group (574 +/- 85 and 535 ml min-1, p = 0.05).	Captopril	80-89	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
7932174-9	1994	Renal clearances of 3-desacetylvecuronium and vecuronium were 0.85 (0.15-1.24) and 0.58 (0.16-0.66) ml.kg-1.min-1, respectively (P &lt; .05).	3-deacetylvecuronium	20-41	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
7815676-5	1994	Nonetheless, glucose oxidation decreased in the LCT group (from 6.42 +/- 1.04 to 2.31 +/- 0.85 mumol/kg.min-1, p &lt; .001) and in the MCT/LCT group (from 7.62 +/- 1.50 to 5.50 +/- 0.76 mumol/kg.min-1, p &lt; .01) but not in the control group.	Glucose	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
7815676-5	1994	Nonetheless, glucose oxidation decreased in the LCT group (from 6.42 +/- 1.04 to 2.31 +/- 0.85 mumol/kg.min-1, p &lt; .001) and in the MCT/LCT group (from 7.62 +/- 1.50 to 5.50 +/- 0.76 mumol/kg.min-1, p &lt; .01) but not in the control group.	Glucose	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	195-200
7943703-5	1994	The oxygen flow was 2 l.min-1 and the average halothane consumption was 8 ml.h-1.	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	24-29
8053580-8	1994	Average population pharmacokinetic parameters from a three-compartment thiopental model were combined with an effect-site rate constant for thiopental equilibration of 0.58 min-1 and a median effect-site concentration of 13.8 mg/l from previously published pharmacokinetic and pharmacodynamic models for thiopental.	Thiopental	140-150	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
8053580-8	1994	Average population pharmacokinetic parameters from a three-compartment thiopental model were combined with an effect-site rate constant for thiopental equilibration of 0.58 min-1 and a median effect-site concentration of 13.8 mg/l from previously published pharmacokinetic and pharmacodynamic models for thiopental.	Thiopental	140-150	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
8053580-14	1994	This model incorporated a four-compartment thiopental pharmacokinetic model with quantal dose-response data to derive an effect-site rate constant for thiopental equilibration of 0.29 min-1 and a median effect-site concentration for LOC of 11.3 mg/l.	Thiopental	151-161	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
7923521-4	1994	Supplemental oxygen was administered at 3 L.min-1 by nasal prongs.	Oxygen	13-19	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
7981012-13	1994	The plasma clearance of unbound R(+)-bupivacaine (7.26 +/- 3.60 1 min-1) was smaller (P &lt; 0.01) than that of S(-)-bupivacaine (8.71 +/- 4.27 l min-1).	Bupivacaine	32-48	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
7981012-13	1994	The plasma clearance of unbound R(+)-bupivacaine (7.26 +/- 3.60 1 min-1) was smaller (P &lt; 0.01) than that of S(-)-bupivacaine (8.71 +/- 4.27 l min-1).	Bupivacaine	32-48	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
7924159-5	1994	After basal samplings, adenosine was infused intra-arterially at successive rates of 2 and 10 micrograms min-1 kg-1 for 40 min at each rate.	Adenosine	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	105-115
7924169-4	1994	In patients, O2 consumption fell exponentially from 16.8 (13.7-20.0) ml min-1 kg-1 at peak exercise to 6.0 (5.2-6.7) ml min-1 kg-1 at 3 min of recovery and in control subjects it fell from 30.2 (27.0-33.5) ml min-1 kg-1 to 6.7 (5.9-7.4) ml min-1 kg-1 (mean and 95% confidence intervals).	Oxygen	13-15	CD59 molecule (CD59 blood group)	Homo sapiens	72-82
7924169-4	1994	In patients, O2 consumption fell exponentially from 16.8 (13.7-20.0) ml min-1 kg-1 at peak exercise to 6.0 (5.2-6.7) ml min-1 kg-1 at 3 min of recovery and in control subjects it fell from 30.2 (27.0-33.5) ml min-1 kg-1 to 6.7 (5.9-7.4) ml min-1 kg-1 (mean and 95% confidence intervals).	Oxygen	13-15	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
7924169-4	1994	In patients, O2 consumption fell exponentially from 16.8 (13.7-20.0) ml min-1 kg-1 at peak exercise to 6.0 (5.2-6.7) ml min-1 kg-1 at 3 min of recovery and in control subjects it fell from 30.2 (27.0-33.5) ml min-1 kg-1 to 6.7 (5.9-7.4) ml min-1 kg-1 (mean and 95% confidence intervals).	Oxygen	13-15	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
7924169-4	1994	In patients, O2 consumption fell exponentially from 16.8 (13.7-20.0) ml min-1 kg-1 at peak exercise to 6.0 (5.2-6.7) ml min-1 kg-1 at 3 min of recovery and in control subjects it fell from 30.2 (27.0-33.5) ml min-1 kg-1 to 6.7 (5.9-7.4) ml min-1 kg-1 (mean and 95% confidence intervals).	Oxygen	13-15	CD59 molecule (CD59 blood group)	Homo sapiens	120-130
7530684-6	1994	CD59 in the PNS and CNS was glycosyl-phosphatidylinositol linked and had a molecular weight of 19,000-25,000.	Glycosylphosphatidylinositols	28-57	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
7822068-6	1994	The oxygen uptake at 15 km.h-1 (VO2 15) was lower (129 vs 138 ml.kg-0.75.min-1, p &lt; 0.01) and the VO2/velocity slope higher in the long-distance runners, with similar VO2 18 in the two groups.	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
8046321-9	1994	RESULTS: Galactose elimination capacity decreased from 2.45 (+/- 0.48) mM min-1 to 2.04 (+/- 0.60) mM min-1 after the five planned courses of chemotherapy (P = 0.013, Wilcoxon signed-rank test), without any change in routine liver function tests.	Galactose	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	74-87
8046321-9	1994	RESULTS: Galactose elimination capacity decreased from 2.45 (+/- 0.48) mM min-1 to 2.04 (+/- 0.60) mM min-1 after the five planned courses of chemotherapy (P = 0.013, Wilcoxon signed-rank test), without any change in routine liver function tests.	Galactose	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
7815284-2	1994	In the presence of an inward H(+)-gradient, the initial uptake rate of ceftibuten by both human and rat intestinal BBMV was concentration-dependent with apparent Km and Vmax values of 0.35 mM and 2.052 nmol (mg protein)-1 min-1 for human BBMV, and 0.50 mM and 3.056 nmol (mg protein)-1 min-1 for rat BBMV, respectively.	Ceftibuten	71-81	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
7815284-2	1994	In the presence of an inward H(+)-gradient, the initial uptake rate of ceftibuten by both human and rat intestinal BBMV was concentration-dependent with apparent Km and Vmax values of 0.35 mM and 2.052 nmol (mg protein)-1 min-1 for human BBMV, and 0.50 mM and 3.056 nmol (mg protein)-1 min-1 for rat BBMV, respectively.	Ceftibuten	71-81	CD59 molecule (CD59 blood group)	Homo sapiens	286-291
7983588-2	1994	The presence of either NaCl or LiCl in the donor solution caused significant fluxes of neostigmine, with permeability coefficients (Kp"s) in the range of 10(-6) cm min-1.	Sodium Chloride	23-27	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
7983588-2	1994	The presence of either NaCl or LiCl in the donor solution caused significant fluxes of neostigmine, with permeability coefficients (Kp"s) in the range of 10(-6) cm min-1.	Lithium Chloride	31-35	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
7983588-2	1994	The presence of either NaCl or LiCl in the donor solution caused significant fluxes of neostigmine, with permeability coefficients (Kp"s) in the range of 10(-6) cm min-1.	Neostigmine	87-98	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
8071856-9	1994	The rates of acrolein formation from CP and IF in human hepatic microsomes (0.76 +/- 0.23 and 0.19 +/- 0.07 nmol min-1 mg-1 of protein, respectively) were only 18% and 10% of the rates estimated in fractions from untreated rat liver (4.20 +/- 0.04 and 1.96 +/- 0.12 nmol min-1 mg-1 of protein, respectively).	Acrolein	13-21	CD59 molecule (CD59 blood group)	Homo sapiens	113-123
8071856-9	1994	The rates of acrolein formation from CP and IF in human hepatic microsomes (0.76 +/- 0.23 and 0.19 +/- 0.07 nmol min-1 mg-1 of protein, respectively) were only 18% and 10% of the rates estimated in fractions from untreated rat liver (4.20 +/- 0.04 and 1.96 +/- 0.12 nmol min-1 mg-1 of protein, respectively).	Acrolein	13-21	CD59 molecule (CD59 blood group)	Homo sapiens	271-281
7933490-1	1994	To prevent hypoxemia during one-lung anesthesia, we have devised an oxygen insufflation machine which can insufflate oxygen (0.2-10 l.min-1) and apply CPAP (0-30 cmH2O) selectively to the non-ventilated lung.	Oxygen	68-74	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
7933490-1	1994	To prevent hypoxemia during one-lung anesthesia, we have devised an oxygen insufflation machine which can insufflate oxygen (0.2-10 l.min-1) and apply CPAP (0-30 cmH2O) selectively to the non-ventilated lung.	Oxygen	117-123	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
7915501-8	1994	Salmeterol was significantly more effective than SR-terbutaline in the following factors: number of patients without any awakening during the last week of treatment (50% vs 27%, P = 0.003), mean morning PEF (351 +/- 109 l/min-1 vs 332 +/- 105 l/min-1, P = 0.04), PEF diurnal variation 6 +/- 10% vs 11 +/- 12%, P = 0.01), overall assessment of efficacy by the patient and the investigator (P = 0.001 and 0.005, respectively), and daily rescue salbutamol intakes (P = 0.004).	Salmeterol Xinafoate	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
7915501-8	1994	Salmeterol was significantly more effective than SR-terbutaline in the following factors: number of patients without any awakening during the last week of treatment (50% vs 27%, P = 0.003), mean morning PEF (351 +/- 109 l/min-1 vs 332 +/- 105 l/min-1, P = 0.04), PEF diurnal variation 6 +/- 10% vs 11 +/- 12%, P = 0.01), overall assessment of efficacy by the patient and the investigator (P = 0.001 and 0.005, respectively), and daily rescue salbutamol intakes (P = 0.004).	Salmeterol Xinafoate	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	245-250
8017334-3	1994	Lipolysis and primary (intraadipocyte) free fatty acid (FFA) reesterification increased 2.5-fold (1.7 +/- 0.2 to 4.2 +/- 0.2 mumol.kg-1.min-1 and 1.5 +/- 0.4 to 4.2 +/- 0.8 mumol.kg-1.min-1, respectively, both P &lt; 0.05).	Fatty Acids, Nonesterified	39-54	CD59 molecule (CD59 blood group)	Homo sapiens	136-149
8068738-8	1994	When this tracer was infused for 160 min in six healthy volunteers, acetate turnover was found to be 7.5 +/- 1 mumol kg-1 min-1, which is similar to data reported with radioactive tracers.	Acetates	68-75	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
8025998-7	1994	Minimal coronary resistance during dipyridamole vasodilation was elevated during rejection (40 +/- 11 mm Hg.mL-1.min-1.g-1); after recovery, it no longer differed from that in the group B patients (26 +/- 11 versus 22 +/- 4 mm Hg.mL-1.min-1.g-1).	Dipyridamole	35-47	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
7517877-5	1994	CD59 on HT29 cells was glycosyl-phosphatidylinositol-linked, and had a molecular mass of 19-25 kDa.	Glycosylphosphatidylinositols	23-52	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
7932174-9	1994	Renal clearances of 3-desacetylvecuronium and vecuronium were 0.85 (0.15-1.24) and 0.58 (0.16-0.66) ml.kg-1.min-1, respectively (P &lt; .05).	Vecuronium Bromide	31-41	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
7933475-6	1994	Intravenous injection of atropine increased heart rate to 60.min-1 only transiently.	Atropine	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
8000156-6	1994	The mean glycerol flux rate of 3.02 +/- 0.37 mumol.kg-1 body wt.min-1 after an overnight fast was similar to values reported from studies with comparable protocols.	Glycerol	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
8000156-7	1994	Physiological changes of lipolysis rates after 48 h of fasting followed by infusion of 4 mg.kg-1 body wt.min-1 glucose could also be adequately studied in one subject.	Glucose	111-118	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
8000156-8	1994	Fast-induced elevated glycerol turnover at 7.56 mumol.kg-1 body wt.min-1, was substantially suppressed to 1.13 mumol.kg-1 body wt.min-1, when glucose was administered.	Glycerol	22-30	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
8000156-8	1994	Fast-induced elevated glycerol turnover at 7.56 mumol.kg-1 body wt.min-1, was substantially suppressed to 1.13 mumol.kg-1 body wt.min-1, when glucose was administered.	Glycerol	22-30	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
8000156-8	1994	Fast-induced elevated glycerol turnover at 7.56 mumol.kg-1 body wt.min-1, was substantially suppressed to 1.13 mumol.kg-1 body wt.min-1, when glucose was administered.	Glucose	142-149	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
8000156-8	1994	Fast-induced elevated glycerol turnover at 7.56 mumol.kg-1 body wt.min-1, was substantially suppressed to 1.13 mumol.kg-1 body wt.min-1, when glucose was administered.	Glucose	142-149	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
7936837-3	1994	During the first 2 postnatal d ethane [24.1 (SEM 7.8) pmol x kg-1 x min-1] and pentane [24.2 (SEM 4.1) pmol x kg-1 x min-1] were stable but increased during d 5 to maxima of 79.1 (15.8) pmol x kg-1 x min-1 and 62.1 (8.1) pmol x kg-1 x min-1, respectively.	pentane	79-86	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
7936837-3	1994	During the first 2 postnatal d ethane [24.1 (SEM 7.8) pmol x kg-1 x min-1] and pentane [24.2 (SEM 4.1) pmol x kg-1 x min-1] were stable but increased during d 5 to maxima of 79.1 (15.8) pmol x kg-1 x min-1 and 62.1 (8.1) pmol x kg-1 x min-1, respectively.	pentane	79-86	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
7936837-3	1994	During the first 2 postnatal d ethane [24.1 (SEM 7.8) pmol x kg-1 x min-1] and pentane [24.2 (SEM 4.1) pmol x kg-1 x min-1] were stable but increased during d 5 to maxima of 79.1 (15.8) pmol x kg-1 x min-1 and 62.1 (8.1) pmol x kg-1 x min-1, respectively.	pentane	79-86	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
7936837-5	1994	Infants with high maximum expired ethane and pentane (exceeding 40 pmol x kg-1 x min-1) had higher odds of dying or having bronchopulmonary dysplasia than those with low ethane and pentane (odds ratio, 6.5; 95% confidence interval, 1.1 to 38.5; p &lt; 0.05 for ethane and odds ratio, 5.6; 95% confidence interval, 1.1 to 29.3; p &lt; 0.05 for pentane).	Ethane	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
7936837-5	1994	Infants with high maximum expired ethane and pentane (exceeding 40 pmol x kg-1 x min-1) had higher odds of dying or having bronchopulmonary dysplasia than those with low ethane and pentane (odds ratio, 6.5; 95% confidence interval, 1.1 to 38.5; p &lt; 0.05 for ethane and odds ratio, 5.6; 95% confidence interval, 1.1 to 29.3; p &lt; 0.05 for pentane).	pentane	45-52	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
7939378-4	1994	Treatment with diltiazem induced a non-significant reduction in heart rate with 3 beats min-1 and decreased blood pressure (-11/-9 mm Hg, p &lt; 0.001).	Diltiazem	15-24	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
7942055-3	1994	Cycling was performed for 22.7 +/- 2.7 min (mean, SE) (fatigue) and oxygen uptake (VO2) increased to 1.90 +/- 0.13 1 min-1.	Oxygen	68-74	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
8010476-6	1994	An infusion of mivacurium was begun at 5 micrograms.kg-1.min-1.	Mivacurium	15-25	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
8023917-1	1994	The effect of an infusion of norepinephrine (0.42 nmol.kg-1.min-1) on energy metabolism in the whole body (using indirect calorimetry and the arteriovenous forearm catheterization techniques in eight healthy young male adults.	Norepinephrine	29-43	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
8203914-7	1994	The enzyme was purified and shown to have a relatively low specific activity with the standard GST substrate 1-chloro-2,4-dinitrobenzene (1.4 +/- 0.2 mumol min-1 mg-1 protein), but an activity equivalent to other Mu class enzymes with other tested substrates.	Dinitrochlorobenzene	109-136	CD59 molecule (CD59 blood group)	Homo sapiens	156-166
7912947-8	1994	Administration of thiopentone significantly increased thenar muscle blood flow from 2.6 (1.9) and 2.2 (1.5) ml min-1/100 g to 19.2 (14) and 21.7 (16) ml min-1/100 g in the balanced anaesthesia and isoflurane groups, respectively (P &lt; 0.001).	Thiopental	18-29	CD59 molecule (CD59 blood group)	Homo sapiens	111-122
7912947-8	1994	Administration of thiopentone significantly increased thenar muscle blood flow from 2.6 (1.9) and 2.2 (1.5) ml min-1/100 g to 19.2 (14) and 21.7 (16) ml min-1/100 g in the balanced anaesthesia and isoflurane groups, respectively (P &lt; 0.001).	Thiopental	18-29	CD59 molecule (CD59 blood group)	Homo sapiens	153-164
7912947-9	1994	The addition of fentanyl (balanced) or isoflurane to the anaesthetic mixture produced further increases in thenar muscle blood flow to reach, respectively, 26.2 (16) and 26.8 (13.6) ml min-1/100 g during steady state anaesthesia.	Fentanyl	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	185-196
7912947-9	1994	The addition of fentanyl (balanced) or isoflurane to the anaesthetic mixture produced further increases in thenar muscle blood flow to reach, respectively, 26.2 (16) and 26.8 (13.6) ml min-1/100 g during steady state anaesthesia.	Isoflurane	39-49	CD59 molecule (CD59 blood group)	Homo sapiens	185-196
7917777-12	1994	Lymphocyte microsomal epoxide hydrolase activity was marginally, but significantly (P = 0.02) higher in the patients (28.4 pmol diol min-1 mg-1 protein) than in drug-free controls (23.4 pmol diol min-1 mg-1 protein (95% CI for difference -9 to -0.8)).	diol	128-132	CD59 molecule (CD59 blood group)	Homo sapiens	133-143
7522216-5	1994	Treatment of PMN with calcium ionophore A23187 resulted in similar increases in CD59 expression.	Calcium	22-29	CD59 molecule (CD59 blood group)	Homo sapiens	80-84
7522216-5	1994	Treatment of PMN with calcium ionophore A23187 resulted in similar increases in CD59 expression.	Calcimycin	40-46	CD59 molecule (CD59 blood group)	Homo sapiens	80-84
7522216-7	1994	Evidence for a mobilizable intracellular pool of CD59 was obtained by detection of increased binding of 1F5 following PMN permeabilization; CD59 could also be re-expressed after stripping by phosphatidylinositol specific phospholipase C (PI-PLC) by treatment with FMLP or A23187.	Phosphatidylinositols	191-211	CD59 molecule (CD59 blood group)	Homo sapiens	49-53
7522216-7	1994	Evidence for a mobilizable intracellular pool of CD59 was obtained by detection of increased binding of 1F5 following PMN permeabilization; CD59 could also be re-expressed after stripping by phosphatidylinositol specific phospholipase C (PI-PLC) by treatment with FMLP or A23187.	Phosphatidylinositols	191-211	CD59 molecule (CD59 blood group)	Homo sapiens	140-144
7522216-7	1994	Evidence for a mobilizable intracellular pool of CD59 was obtained by detection of increased binding of 1F5 following PMN permeabilization; CD59 could also be re-expressed after stripping by phosphatidylinositol specific phospholipase C (PI-PLC) by treatment with FMLP or A23187.	Calcimycin	272-278	CD59 molecule (CD59 blood group)	Homo sapiens	49-53
7522216-7	1994	Evidence for a mobilizable intracellular pool of CD59 was obtained by detection of increased binding of 1F5 following PMN permeabilization; CD59 could also be re-expressed after stripping by phosphatidylinositol specific phospholipase C (PI-PLC) by treatment with FMLP or A23187.	Calcimycin	272-278	CD59 molecule (CD59 blood group)	Homo sapiens	140-144
7918787-6	1994	The respective mean (+/- SD) high- and low-affinity component kinetic parameters for the 5-hydroxylation and sulphoxidation of omeprazole estimated by a two-enzyme kinetic analysis were: Km1 = 6.3 +/- 1.7 and 10.4 +/- 6.3 microM, Km2 = 183.2 +/- 180.4 and 671.2 +/- 639.4 microM, Vmax1 = 109.8 +/- 75.4 and 77.5 +/- 46.1 pmol mg-1 min-1, and Vmax2 = 163.3 +/- 94.1 and 318.3 +/- 163.3 pmol mg-1 min-1.	Omeprazole	127-137	CD59 molecule (CD59 blood group)	Homo sapiens	331-336
7918787-6	1994	The respective mean (+/- SD) high- and low-affinity component kinetic parameters for the 5-hydroxylation and sulphoxidation of omeprazole estimated by a two-enzyme kinetic analysis were: Km1 = 6.3 +/- 1.7 and 10.4 +/- 6.3 microM, Km2 = 183.2 +/- 180.4 and 671.2 +/- 639.4 microM, Vmax1 = 109.8 +/- 75.4 and 77.5 +/- 46.1 pmol mg-1 min-1, and Vmax2 = 163.3 +/- 94.1 and 318.3 +/- 163.3 pmol mg-1 min-1.	Omeprazole	127-137	CD59 molecule (CD59 blood group)	Homo sapiens	395-400
7518124-0	1994	Enhancement of the complement regulatory function of CD59 by site-directed mutagenesis at the N-glycosylation site.	Nitrogen	94-95	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
8180209-6	1994	Furthermore, vesicles containing plasmenylethanolamines in physiologic ratios with other phospholipids (i.e., PC/PE/PS, 45:45:10, mol/mol) underwent fusion six times more rapidly (4.4Fmax% min-1) than corresponding vesicles in which plasmenylethanolamine was replaced with phosphatidylethanolamine (0.7Fmax% min-1).	phosphatidal ethanolamines	33-55	CD59 molecule (CD59 blood group)	Homo sapiens	189-194
8180209-6	1994	Furthermore, vesicles containing plasmenylethanolamines in physiologic ratios with other phospholipids (i.e., PC/PE/PS, 45:45:10, mol/mol) underwent fusion six times more rapidly (4.4Fmax% min-1) than corresponding vesicles in which plasmenylethanolamine was replaced with phosphatidylethanolamine (0.7Fmax% min-1).	phosphatidal ethanolamines	33-55	CD59 molecule (CD59 blood group)	Homo sapiens	308-313
8180209-6	1994	Furthermore, vesicles containing plasmenylethanolamines in physiologic ratios with other phospholipids (i.e., PC/PE/PS, 45:45:10, mol/mol) underwent fusion six times more rapidly (4.4Fmax% min-1) than corresponding vesicles in which plasmenylethanolamine was replaced with phosphatidylethanolamine (0.7Fmax% min-1).	phosphatidal ethanolamines	33-54	CD59 molecule (CD59 blood group)	Homo sapiens	189-194
8180209-6	1994	Furthermore, vesicles containing plasmenylethanolamines in physiologic ratios with other phospholipids (i.e., PC/PE/PS, 45:45:10, mol/mol) underwent fusion six times more rapidly (4.4Fmax% min-1) than corresponding vesicles in which plasmenylethanolamine was replaced with phosphatidylethanolamine (0.7Fmax% min-1).	phosphatidal ethanolamines	33-54	CD59 molecule (CD59 blood group)	Homo sapiens	308-313
7514386-0	1994	Structural study on the glycosyl-phosphatidylinositol anchor and the asparagine-linked sugar chain of a soluble form of CD59 in human urine.	Glycosylphosphatidylinositols	24-53	CD59 molecule (CD59 blood group)	Homo sapiens	120-124
7514386-0	1994	Structural study on the glycosyl-phosphatidylinositol anchor and the asparagine-linked sugar chain of a soluble form of CD59 in human urine.	Asparagine	69-79	CD59 molecule (CD59 blood group)	Homo sapiens	120-124
7514386-0	1994	Structural study on the glycosyl-phosphatidylinositol anchor and the asparagine-linked sugar chain of a soluble form of CD59 in human urine.	Sugars	87-92	CD59 molecule (CD59 blood group)	Homo sapiens	120-124
7514386-2	1994	An important structural feature of CD59 is its attachment to the cell surface via a glycosyl-phosphatidylinositol (GPI) anchor.	Glycosylphosphatidylinositols	84-113	CD59 molecule (CD59 blood group)	Homo sapiens	35-39
7514386-2	1994	An important structural feature of CD59 is its attachment to the cell surface via a glycosyl-phosphatidylinositol (GPI) anchor.	Glycosylphosphatidylinositols	115-118	CD59 molecule (CD59 blood group)	Homo sapiens	35-39
7514386-4	1994	The structures of the GPI anchor and the asparagine-linked sugar chain of a soluble form of CD59 in urine, U-CD59, were determined.	Glycosylphosphatidylinositols	22-25	CD59 molecule (CD59 blood group)	Homo sapiens	92-96
7514386-4	1994	The structures of the GPI anchor and the asparagine-linked sugar chain of a soluble form of CD59 in urine, U-CD59, were determined.	Glycosylphosphatidylinositols	22-25	CD59 molecule (CD59 blood group)	Homo sapiens	109-113
7514386-4	1994	The structures of the GPI anchor and the asparagine-linked sugar chain of a soluble form of CD59 in urine, U-CD59, were determined.	Asparagine	41-51	CD59 molecule (CD59 blood group)	Homo sapiens	92-96
7514386-4	1994	The structures of the GPI anchor and the asparagine-linked sugar chain of a soluble form of CD59 in urine, U-CD59, were determined.	Asparagine	41-51	CD59 molecule (CD59 blood group)	Homo sapiens	109-113
7514386-4	1994	The structures of the GPI anchor and the asparagine-linked sugar chain of a soluble form of CD59 in urine, U-CD59, were determined.	Sugars	59-64	CD59 molecule (CD59 blood group)	Homo sapiens	92-96
7514386-5	1994	Purified U-CD59 released 1 mol of inositol per mole of protein by nitrous acid deamination, which cleaved between glucosamine and inositol present commonly in the GPI anchor.	Inositol	34-42	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
7514386-5	1994	Purified U-CD59 released 1 mol of inositol per mole of protein by nitrous acid deamination, which cleaved between glucosamine and inositol present commonly in the GPI anchor.	Nitrous Acid	66-78	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
7514386-5	1994	Purified U-CD59 released 1 mol of inositol per mole of protein by nitrous acid deamination, which cleaved between glucosamine and inositol present commonly in the GPI anchor.	Glucosamine	114-125	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
7514386-5	1994	Purified U-CD59 released 1 mol of inositol per mole of protein by nitrous acid deamination, which cleaved between glucosamine and inositol present commonly in the GPI anchor.	Inositol	130-138	CD59 molecule (CD59 blood group)	Homo sapiens	11-15
7514386-6	1994	This indicates that a GPI anchor, which ended with inositol, is linked at the carboxy terminus of U-CD59.	Inositol	51-59	CD59 molecule (CD59 blood group)	Homo sapiens	100-104
7514386-7	1994	The peptide containing an asparagine-linked sugar chain and the peptide containing a glycan portion of the GPI anchor were isolated after trypsin digestion of U-CD59.	Glycosylphosphatidylinositols	107-110	CD59 molecule (CD59 blood group)	Homo sapiens	161-165
7514386-10	1994	The structures of the asparagine-linked sugar chains of U-CD59 were biantennary complex type, only 4.2% of which are monosialylated.	Asparagine	22-32	CD59 molecule (CD59 blood group)	Homo sapiens	58-62
7514386-10	1994	The structures of the asparagine-linked sugar chains of U-CD59 were biantennary complex type, only 4.2% of which are monosialylated.	Sugars	40-45	CD59 molecule (CD59 blood group)	Homo sapiens	58-62
7514386-10	1994	The structures of the asparagine-linked sugar chains of U-CD59 were biantennary complex type, only 4.2% of which are monosialylated.	Uranium	56-57	CD59 molecule (CD59 blood group)	Homo sapiens	58-62
8188711-4	1994	In the presence of calmodulin and p-trifluoromethoxyphenylhydrazone, the reconstituted system sustained transport rates of 1.00 +/- 0.12 mumol of Ca2+/mg of protein min-1 (30 degrees C), reaching asymptotic levels of 8.05 +/- 0.41 mumol of Ca2+/mg of protein (i.e. 20 mM lumenal Ca2+).	p-trifluoromethoxyphenylhydrazone	34-67	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
7915914-2	1994	The enzyme incorporated [3H]inositol into phosphoinositides at a maximal rate of 419 pmol min-1 mg protein-1.	3h]inositol	25-36	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
7915914-2	1994	The enzyme incorporated [3H]inositol into phosphoinositides at a maximal rate of 419 pmol min-1 mg protein-1.	Phosphatidylinositols	42-59	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
7915914-3	1994	In the absence of CMP, the labelling rate due to the PtdIns headgroup exchanging enzyme was 36 pmol min-1 mg protein-1.	Phosphatidylinositols	53-59	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
8085501-9	1994	During progressive treadmill tests, the heart rate interpolated to oxygen consumptions of 10 and 15 ml.kg-1.min-1 had CV = 4% and 7%, respectively.	Oxygen	67-73	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
7909212-3	1994	Vecuronium, 3 micrograms.kg-1.min-1, was infused for 10 min, venous blood sampled for 60 min, and twitch tension and plasma concentration data were used to determine pharmacodynamic variables in each patient.	Vecuronium Bromide	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
7909212-6	1994	For the hypothermic and normothermic patients, respectively, steady-state plasma concentrations of vecuronium producing 50% neuromuscular block (Css50) were 73 +/- 13 ng/mL (mean +/- SD) and 79 +/- 31 ng/mL; the rate constants for equilibration of vecuronium between the plasma and the neuromuscular junction (Keo) were 0.27 +/- 0.14 per min-1 and 0.26 +/- 0.11 per min, and the power functions representing the slope of the concentration-effect relationship (gamma) were 5.7 +/- 1.9 and 4.4 +/- 1.8.	Vecuronium Bromide	99-109	CD59 molecule (CD59 blood group)	Homo sapiens	338-343
8160978-8	1994	The group of patients who received propofol alone required an average propofol dose of 221.5 +/- 71.9 micrograms.kg-1.min-1 to maintain anesthesia compared with 162.5 +/- 43.9 micrograms.kg-1.min-1 for the group receiving propofol plus nitrous oxide (P &lt; 0.001).	Propofol	70-78	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
8160978-8	1994	The group of patients who received propofol alone required an average propofol dose of 221.5 +/- 71.9 micrograms.kg-1.min-1 to maintain anesthesia compared with 162.5 +/- 43.9 micrograms.kg-1.min-1 for the group receiving propofol plus nitrous oxide (P &lt; 0.001).	Propofol	70-78	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
8054249-7	1994	Changes in venous compliance and blood flow were measured by venous occlusion plethysmography using a basal infusion of noradrenaline (1 microgram min-1) to increase venous tone.	Norepinephrine	120-133	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
8068867-3	1994	For the 6-hydroxylation of chlorzoxazone (P450 2E1) the predicted and actual clearances were 110 +/- 77 mL min-1 and 110 mL min-1, respectively.	Chlorzoxazone	27-40	CD59 molecule (CD59 blood group)	Homo sapiens	107-129
8068867-5	1994	An increase to 72 +/- 25 mL min-1 in the CLH of cortisol to 6 beta-hydroxycortisol was calculated following rifampicin treatment.	beta-hydroxycortisol	62-82	CD59 molecule (CD59 blood group)	Homo sapiens	28-33
8068867-5	1994	An increase to 72 +/- 25 mL min-1 in the CLH of cortisol to 6 beta-hydroxycortisol was calculated following rifampicin treatment.	Rifampin	108-118	CD59 molecule (CD59 blood group)	Homo sapiens	28-33
7524616-4	1994	Moreover, they lack surface expression of complement regulatory proteins such as DAF (CD55) and CD59, that are the most important glycosylphosphatidylinositol (GPI)-anchored membrane proteins defective in haemopoietic cells of patients with PNH.	Glycosylphosphatidylinositols	130-158	CD59 molecule (CD59 blood group)	Homo sapiens	96-100
7524616-4	1994	Moreover, they lack surface expression of complement regulatory proteins such as DAF (CD55) and CD59, that are the most important glycosylphosphatidylinositol (GPI)-anchored membrane proteins defective in haemopoietic cells of patients with PNH.	Glycosylphosphatidylinositols	160-163	CD59 molecule (CD59 blood group)	Homo sapiens	96-100
8026143-5	1994	Glucose cycling was increased by 111% in NIDDM patients (118 +/- 18 mumole min-1 vs. 56 +/- 11 in controls, P &lt; 0.05) and was positively correlated with plasma glucose concentration (r = 0.831, P &lt; 0.001) and with non-oxidative glucose disposal (r = 0.714, P &lt; 0.01).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
8181198-12	1994	RESULTS: The rate of change of plasma concentrations averaged 21 +/- 4 ng/ml.min-1 during fast infusion and 5 +/- 1 ng/ml.min-1 during slow infusion of temazepam.	Temazepam	152-161	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
8181198-12	1994	RESULTS: The rate of change of plasma concentrations averaged 21 +/- 4 ng/ml.min-1 during fast infusion and 5 +/- 1 ng/ml.min-1 during slow infusion of temazepam.	Temazepam	152-161	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
7519171-0	1994	High-density lipoproteins can act as carriers of glycophosphoinositol lipid-anchored CD59 in human plasma.	glycophosphoinositol lipid	49-75	CD59 molecule (CD59 blood group)	Homo sapiens	85-89
7519171-1	1994	CD59 (protectin) is a glycophosphoinositol (GPI) lipid-anchored inhibitor of complement lysis that is expressed on the membranes of blood cells, endothelial cells, epithelial cells and cardiomyocytes.	glycophosphoinositol	22-42	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
7519171-1	1994	CD59 (protectin) is a glycophosphoinositol (GPI) lipid-anchored inhibitor of complement lysis that is expressed on the membranes of blood cells, endothelial cells, epithelial cells and cardiomyocytes.	GPI 1046	44-47	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
8190106-9	1994	The dissociation rate constant (k-1) for [3H]Ba 679 BR was 3.29 +/- 0.18 x 10(-3) min-1, corresponding to a half-life of the complex of 212 +/- 11 min.	Tritium	42-44	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
7996384-4	1994	Kinetic analysis of the concentration dependence of the permeation rate of salicylic acid across Caco-2 cells showed both saturable (Kt = 5.28 +/- 0.72 mM Jmax = 36.6 +/- 3.54 nmol min-1 (mg protein)-1) and nonsaturable (kd = 0.37 +/- 0.08 microL min-1 (mg protein)-1) processes.	Salicylic Acid	75-89	CD59 molecule (CD59 blood group)	Homo sapiens	181-201
7996384-4	1994	Kinetic analysis of the concentration dependence of the permeation rate of salicylic acid across Caco-2 cells showed both saturable (Kt = 5.28 +/- 0.72 mM Jmax = 36.6 +/- 3.54 nmol min-1 (mg protein)-1) and nonsaturable (kd = 0.37 +/- 0.08 microL min-1 (mg protein)-1) processes.	Salicylic Acid	75-89	CD59 molecule (CD59 blood group)	Homo sapiens	247-267
8190106-9	1994	The dissociation rate constant (k-1) for [3H]Ba 679 BR was 3.29 +/- 0.18 x 10(-3) min-1, corresponding to a half-life of the complex of 212 +/- 11 min.	Barium	45-47	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
7512825-1	1994	The cell surface antigen CD59 is an inhibitor of complement-mediated lysis and a member of the Ly6 superfamily (Ly6SF) of cysteine-rich cell-surface molecules whose sequences are related to those of snake venom neurotoxins.	Cysteine	122-130	CD59 molecule (CD59 blood group)	Homo sapiens	25-29
8015171-7	1994	Balanced anesthesia with analgesics, vecuronium bromide and calcium blocker (diltiazem 0.5 microgram.kg-1.min-1) had been advocated to maintain the stable circulatory state.	Diltiazem	77-86	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
7912877-12	1994	Intraoperatively systolic and diastolic arterial pressure were 15% and 13% lower in DP group (P &lt; 0.01 and P &lt; 0.05 for drug effect), the mean heart rate was approximately 9 beats min-1 lower in DP group (n.s.).	dp	84-86	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
7912877-13	1994	Fentanyl was required more often in MF group: median 3.5 (QD 1.5) vs. 2.5 (QD 0.5) times in DP group (P &lt; 0.05), the total amount being 57% smaller in DP group: 0.03 (QD 0.01) vs. 0.07 (QD 0.02) micrograms kg-1 min-1 (P &lt; 0.05).	Fentanyl	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	214-219
7907847-2	1994	Vecuronium (0.02 mg/kg followed by 0.2 mg.kg-1 x h-1) caused a significant decrease of 16.1% +/- 3.87% in inulin clearance from 0.92 +/- 0.07 to 0.71 +/- 0.05 mL.min-1 x gKW-1 (gram of kidney weight), and a decrease in para-aminohippuric acid clearance by 21.6% +/- 4.69% from 1.58 +/- 0.26 to 1.31 +/- 0.20 mL.min-1 x gKW-1 (P &lt; 0.05), whereas succinylcholine (0.45 mg/kg followed by 2 mg.kg-1 x h-1) altered neither.	Vecuronium Bromide	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
8036904-4	1994	The maximal leg oxygen uptake was 0.72 +/- 0.07 l min-1 (0.33 +/- 0.03 l kg-1 min-1).	Oxygen	16-22	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
8036904-4	1994	The maximal leg oxygen uptake was 0.72 +/- 0.07 l min-1 (0.33 +/- 0.03 l kg-1 min-1).	Oxygen	16-22	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
8024133-14	1994	DCO repeatability coefficient was 0.51 l.min-1.	3,3-DICHLORO-2-PHOSPHONOMETHYL-ACRYLIC ACID	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
7907847-2	1994	Vecuronium (0.02 mg/kg followed by 0.2 mg.kg-1 x h-1) caused a significant decrease of 16.1% +/- 3.87% in inulin clearance from 0.92 +/- 0.07 to 0.71 +/- 0.05 mL.min-1 x gKW-1 (gram of kidney weight), and a decrease in para-aminohippuric acid clearance by 21.6% +/- 4.69% from 1.58 +/- 0.26 to 1.31 +/- 0.20 mL.min-1 x gKW-1 (P &lt; 0.05), whereas succinylcholine (0.45 mg/kg followed by 2 mg.kg-1 x h-1) altered neither.	Vecuronium Bromide	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	311-316
8155446-7	1994	With desflurane, heart rate remained at 60-67 beat min-1 at all times before cardiopulmonary bypass.	Desflurane	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
8155446-8	1994	This was always lower than the fentanyl group by 5-15 beat min-1 and the difference was significant at induction, during skin preparation and before aortic cannulation.	Fentanyl	31-39	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
8063042-3	1994	Insulin stimulated glucose uptake was decreased in the diabetic subjects (19.8 +/- 3.0 mumol.kg LBM-1.min-1, both p &lt; 0.001) compared with control subjects (44.1 +/- 2.5 mumol.kg LBM-1.min-1) and relatives (39.9 +/- 3.3 mumol.kg LBM-1.min-1).	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
8033534-2	1994	Computing disappearance rates of glucose from its infused amounts necessary to maintain euglycaemia during 65 h after the insulin injection in analogy to experimental hyperinsulinaemic euglycaemic clamp examinations, a glucose consumption of 55.6 mumol kg-1 min-1 was found at peak serum insulin concentrations of about 14,400 pmol l-1.	Glucose	33-40	CD59 molecule (CD59 blood group)	Homo sapiens	258-263
8033534-3	1994	The insulin-induced glucose dynamics resemble closely those seen in healthy persons and Type 1 diabetic subjects during a 10 mU kg-1 min-1 euglycaemic clamp.	Glucose	20-27	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
8063042-3	1994	Insulin stimulated glucose uptake was decreased in the diabetic subjects (19.8 +/- 3.0 mumol.kg LBM-1.min-1, both p &lt; 0.001) compared with control subjects (44.1 +/- 2.5 mumol.kg LBM-1.min-1) and relatives (39.9 +/- 3.3 mumol.kg LBM-1.min-1).	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
8063042-3	1994	Insulin stimulated glucose uptake was decreased in the diabetic subjects (19.8 +/- 3.0 mumol.kg LBM-1.min-1, both p &lt; 0.001) compared with control subjects (44.1 +/- 2.5 mumol.kg LBM-1.min-1) and relatives (39.9 +/- 3.3 mumol.kg LBM-1.min-1).	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
7518799-8	1994	CD59 was expressed on the U937 subline at similar levels to that on HL60 and K562 cells, was glycosylphosphatidylinositol (GPI) anchored and could be immunoprecipitated from cell extracts.	Glycosylphosphatidylinositols	93-121	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
8144002-6	1994	RESULTS: Esophageal perfusion with saline resulted in luminal release of mucin at the rate of 0.23 +/- 0.03 mg.cm-2 x min-1.	Sodium Chloride	35-41	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
8064115-2	1994	This method is based on the measurement of the oxidation rate of reduced cytochrome c by H2O2 in the presence of a mediator and permits the detection of H2O2 generation rates as low as 60 nM min-1.	Hydrogen Peroxide	89-93	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
8064115-2	1994	This method is based on the measurement of the oxidation rate of reduced cytochrome c by H2O2 in the presence of a mediator and permits the detection of H2O2 generation rates as low as 60 nM min-1.	Hydrogen Peroxide	153-157	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
7518799-8	1994	CD59 was expressed on the U937 subline at similar levels to that on HL60 and K562 cells, was glycosylphosphatidylinositol (GPI) anchored and could be immunoprecipitated from cell extracts.	Glycosylphosphatidylinositols	123-126	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
8117720-2	1994	Like p-nitrophenyl phosphate (pNPP), ANPP is hydrolyzed by the enzyme only in the presence of calcium and magnesium (K0.5 and Vmax are 0.3 mM and 60 nmol mg-1 min-1, respectively).	nitrophenylphosphate	30-34	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
7520819-3	1994	RESULTS: CD59 was purified from human urine, retaining the N-glycan and at least some of the non-lipid component of the glycosylphosphatidylinositol membrane anchor.	n-glycan	59-67	CD59 molecule (CD59 blood group)	Homo sapiens	9-13
7520819-3	1994	RESULTS: CD59 was purified from human urine, retaining the N-glycan and at least some of the non-lipid component of the glycosylphosphatidylinositol membrane anchor.	Glycosylphosphatidylinositols	120-148	CD59 molecule (CD59 blood group)	Homo sapiens	9-13
8117720-2	1994	Like p-nitrophenyl phosphate (pNPP), ANPP is hydrolyzed by the enzyme only in the presence of calcium and magnesium (K0.5 and Vmax are 0.3 mM and 60 nmol mg-1 min-1, respectively).	4-azido-2-nitrophenyl phosphate	37-41	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
8117720-2	1994	Like p-nitrophenyl phosphate (pNPP), ANPP is hydrolyzed by the enzyme only in the presence of calcium and magnesium (K0.5 and Vmax are 0.3 mM and 60 nmol mg-1 min-1, respectively).	Calcium	94-101	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
8117720-2	1994	Like p-nitrophenyl phosphate (pNPP), ANPP is hydrolyzed by the enzyme only in the presence of calcium and magnesium (K0.5 and Vmax are 0.3 mM and 60 nmol mg-1 min-1, respectively).	Magnesium	106-115	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
8147509-5	1994	However, there was a significant correlation between respiratory response to carbon dioxide and pulse rate and on restricting analysis to those patients with a pulse rate equal to or less than 72 beat.min-1, the ethnic difference in carbon dioxide response disappeared.	Carbon Dioxide	77-91	CD59 molecule (CD59 blood group)	Homo sapiens	201-206
8147509-5	1994	However, there was a significant correlation between respiratory response to carbon dioxide and pulse rate and on restricting analysis to those patients with a pulse rate equal to or less than 72 beat.min-1, the ethnic difference in carbon dioxide response disappeared.	Carbon Dioxide	233-247	CD59 molecule (CD59 blood group)	Homo sapiens	201-206
8130049-2	1994	Initially we studied 10 children undergoing minor procedures with spontaneous ventilation; mean duration of surgery was 38 min and mean propofol infusion rate 497 micrograms kg-1 min-1.	Propofol	136-144	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
8130049-6	1994	Mean propofol infusion rate required to maintain anaesthesia was 474 micrograms kg-1 min-1 (range 125-737 micrograms kg-1 min-1).	Propofol	5-13	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
8130049-6	1994	Mean propofol infusion rate required to maintain anaesthesia was 474 micrograms kg-1 min-1 (range 125-737 micrograms kg-1 min-1).	Propofol	5-13	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
8198931-7	1994	kinetic parameters for the N-demethylation and 2-hydroxylation of imipramine derived from a two-enzyme kinetic analysis were: Km1 = 1.1 +/- 0.4 and 1.6 +/- 0.6 microM, Vmax1 = 0.11 +/- 0.03 and 0.15 +/- 0.07 nmol mg-1 min-1, and Vmax1/Km1 = 0.10 +/- 0.02 and 0.09 +/- 0.04 ml mg-1 min-1; Km2 = 214 +/- 84 and 257 +/- 148 microM, Vmax2 = 2.22 +/- 0.69 and 0.53 +/- 0.15 nmol mg-1 min-1, and Vmax2/Km2 = 0.011 +/- 0.001 and 0.003 +/- 0.002 ml mg-1 min-1.	Imipramine	66-76	CD59 molecule (CD59 blood group)	Homo sapiens	218-223
8198931-7	1994	kinetic parameters for the N-demethylation and 2-hydroxylation of imipramine derived from a two-enzyme kinetic analysis were: Km1 = 1.1 +/- 0.4 and 1.6 +/- 0.6 microM, Vmax1 = 0.11 +/- 0.03 and 0.15 +/- 0.07 nmol mg-1 min-1, and Vmax1/Km1 = 0.10 +/- 0.02 and 0.09 +/- 0.04 ml mg-1 min-1; Km2 = 214 +/- 84 and 257 +/- 148 microM, Vmax2 = 2.22 +/- 0.69 and 0.53 +/- 0.15 nmol mg-1 min-1, and Vmax2/Km2 = 0.011 +/- 0.001 and 0.003 +/- 0.002 ml mg-1 min-1.	Imipramine	66-76	CD59 molecule (CD59 blood group)	Homo sapiens	281-286
8198931-7	1994	kinetic parameters for the N-demethylation and 2-hydroxylation of imipramine derived from a two-enzyme kinetic analysis were: Km1 = 1.1 +/- 0.4 and 1.6 +/- 0.6 microM, Vmax1 = 0.11 +/- 0.03 and 0.15 +/- 0.07 nmol mg-1 min-1, and Vmax1/Km1 = 0.10 +/- 0.02 and 0.09 +/- 0.04 ml mg-1 min-1; Km2 = 214 +/- 84 and 257 +/- 148 microM, Vmax2 = 2.22 +/- 0.69 and 0.53 +/- 0.15 nmol mg-1 min-1, and Vmax2/Km2 = 0.011 +/- 0.001 and 0.003 +/- 0.002 ml mg-1 min-1.	Imipramine	66-76	CD59 molecule (CD59 blood group)	Homo sapiens	281-286
8198931-7	1994	kinetic parameters for the N-demethylation and 2-hydroxylation of imipramine derived from a two-enzyme kinetic analysis were: Km1 = 1.1 +/- 0.4 and 1.6 +/- 0.6 microM, Vmax1 = 0.11 +/- 0.03 and 0.15 +/- 0.07 nmol mg-1 min-1, and Vmax1/Km1 = 0.10 +/- 0.02 and 0.09 +/- 0.04 ml mg-1 min-1; Km2 = 214 +/- 84 and 257 +/- 148 microM, Vmax2 = 2.22 +/- 0.69 and 0.53 +/- 0.15 nmol mg-1 min-1, and Vmax2/Km2 = 0.011 +/- 0.001 and 0.003 +/- 0.002 ml mg-1 min-1.	Imipramine	66-76	CD59 molecule (CD59 blood group)	Homo sapiens	281-286
8198935-2	1994	Dopamine (DA) at low doses (2.5 micrograms kg-1 min-1) produces a measurable increase in glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) in young healthy subjects and has a therapeutic effect in younger patients with congestive cardiac failure (CCF).	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
8198935-2	1994	Dopamine (DA) at low doses (2.5 micrograms kg-1 min-1) produces a measurable increase in glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) in young healthy subjects and has a therapeutic effect in younger patients with congestive cardiac failure (CCF).	Dopamine	10-12	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
8033956-7	1994	The plasma clearance of DOPA was 1.02 1 min-1.	Dihydroxyphenylalanine	24-28	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
8033956-9	1994	The DOPA appearance rate was 1.13 micrograms min-1 and the extremities accounted for approximately 1/5 of this value.	Dihydroxyphenylalanine	4-8	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
8190529-10	1994	Immunosuppressive treatment with cyclosporin therapy in combination with a minimal dose of alternate-day prednisone would then result in optimal post-transplant growth, particularly if the GFR remains above 50 mL/min/1.73 m2).	Cyclosporine	33-44	CD59 molecule (CD59 blood group)	Homo sapiens	213-218
8190529-10	1994	Immunosuppressive treatment with cyclosporin therapy in combination with a minimal dose of alternate-day prednisone would then result in optimal post-transplant growth, particularly if the GFR remains above 50 mL/min/1.73 m2).	Prednisone	105-115	CD59 molecule (CD59 blood group)	Homo sapiens	213-218
7513901-8	1994	The maximal velocity for phloridzin-sensitive alpha-methyl glucose transport averaged 13.7 +/- 1.7 nmol min-1 mg-1 for C70 cells and only 6.3 +/- 1.3 nmol min-1 mg-1 for C200 cells which is approximately one order of magnitude smaller than what can be expected from a tubule presenting a good access to luminal membrane.	Phlorhizin	25-35	CD59 molecule (CD59 blood group)	Homo sapiens	104-114
7513901-8	1994	The maximal velocity for phloridzin-sensitive alpha-methyl glucose transport averaged 13.7 +/- 1.7 nmol min-1 mg-1 for C70 cells and only 6.3 +/- 1.3 nmol min-1 mg-1 for C200 cells which is approximately one order of magnitude smaller than what can be expected from a tubule presenting a good access to luminal membrane.	Phlorhizin	25-35	CD59 molecule (CD59 blood group)	Homo sapiens	155-165
7513901-8	1994	The maximal velocity for phloridzin-sensitive alpha-methyl glucose transport averaged 13.7 +/- 1.7 nmol min-1 mg-1 for C70 cells and only 6.3 +/- 1.3 nmol min-1 mg-1 for C200 cells which is approximately one order of magnitude smaller than what can be expected from a tubule presenting a good access to luminal membrane.	methylglucoside	46-66	CD59 molecule (CD59 blood group)	Homo sapiens	104-114
8191901-5	1994	Ra peaked at 42.0 +/- 3.2 mumol kg-1 min-1 after approximately 15 min of exercise.	Radium	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
8129119-5	1994	Supplementary sufentanil 25 micrograms was given whenever the systolic arterial blood pressure increased more than 15 mmHg above the pre-operative value, whenever heart rate exceeded 90 beat.min-1 in the absence of hypovolaemia, or when other autonomic or somatic signs occurred.	Sufentanil	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
8311293-5	1994	Additional data were collected during hypercarbic conditions and during a lower infusion rate of propofol (100 micrograms.kg-1 x min-1) combined with 70% nitrous oxide.	Propofol	97-105	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
8143428-2	1994	The effect of infusion of noradrenaline (0.42 mumol min-1 kg-1) on the exchange of nonesterified fatty acids, glycerol and other metabolites across subcutaneous abdominal adipose tissue was investigated in five healthy subjects using an arteriovenous catheterization technique and measurement of adipose tissue blood flow using the 133Xe clearance technique.	Norepinephrine	26-39	CD59 molecule (CD59 blood group)	Homo sapiens	52-62
8143428-2	1994	The effect of infusion of noradrenaline (0.42 mumol min-1 kg-1) on the exchange of nonesterified fatty acids, glycerol and other metabolites across subcutaneous abdominal adipose tissue was investigated in five healthy subjects using an arteriovenous catheterization technique and measurement of adipose tissue blood flow using the 133Xe clearance technique.	Fatty Acids, Nonesterified	83-108	CD59 molecule (CD59 blood group)	Homo sapiens	52-62
8143428-2	1994	The effect of infusion of noradrenaline (0.42 mumol min-1 kg-1) on the exchange of nonesterified fatty acids, glycerol and other metabolites across subcutaneous abdominal adipose tissue was investigated in five healthy subjects using an arteriovenous catheterization technique and measurement of adipose tissue blood flow using the 133Xe clearance technique.	Glycerol	110-118	CD59 molecule (CD59 blood group)	Homo sapiens	52-62
8005123-9	1994	Peak rate-pressure product during steady-state dobutamine infusion (18.493 +/- 4.315 mmHg.min-1) was significantly lower (P &lt; 0.01) than during EST (21.316 +/- 4.937 mmHg.min-1).	Dobutamine	47-57	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
8175583-6	1994	The mean maximal decrease in pulmonary vascular resistance index, 48.8 +/- 9.6%, occurred at an adenosine infusion rate of 30 micrograms.kg-1.min-1, whereas the systemic vascular resistance index remained unchanged.	Adenosine	96-105	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
7507966-10	1994	DAF is a glycosylphosphatidylinositol-linked protein that is released from HUVEC by a phosphatidylinositol-specific phospholipase C. Although HUVEC also contain the glycosylphosphatidylinositol-anchored complement inhibitor CD59, this was not released during a 24-h incubation, suggesting that the shedding of DAF from HUVEC is not caused by PI-PLC but by other enzymes, possibly proteinases.	Glycosylphosphatidylinositols	9-37	CD59 molecule (CD59 blood group)	Homo sapiens	224-228
8158883-4	1994	The mean fall in glomerular filtration rate in 18 enalapril-treated patients is 8.4 +/- 9.4 ml/min/1.73 m2 after four years; 7.5 +/- 9.8 ml/min/1.73 m2, occurred during the first six months treatment.	Enalapril	50-59	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
8158883-4	1994	The mean fall in glomerular filtration rate in 18 enalapril-treated patients is 8.4 +/- 9.4 ml/min/1.73 m2 after four years; 7.5 +/- 9.8 ml/min/1.73 m2, occurred during the first six months treatment.	Enalapril	50-59	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
8121298-2	1994	In the present study, 10 patients suffering from congestive heart failure and 10 healthy age- and body mass index-matched subjects were submitted to a hyperinsulinemic (insulin infusion rate, 0.5 mU/kg.min-1) glucose clamp, while simultaneous D-3H-glucose infusion and indirect calorimetry allowed for determination of glucose turnover parameters and substrate oxidation, respectively.	Glucose	209-216	CD59 molecule (CD59 blood group)	Homo sapiens	202-207
8164326-2	1994	The author measured blood gases, blood sugar, L/P, ATP, the deformability of red blood cell, 2,3-DPG, and P50 in patients who had intravenous administration of low dose of PGE1 (0.05-0.1 microgram.kg-1 x min-1, n = 10), NIC (1.0-5.0 micrograms.kg-1 x min-1, n = 10) and TNG (0.5-1.0 microgram.kg-1 x min-1, n = 10).	Alprostadil	172-176	CD59 molecule (CD59 blood group)	Homo sapiens	204-209
8164326-2	1994	The author measured blood gases, blood sugar, L/P, ATP, the deformability of red blood cell, 2,3-DPG, and P50 in patients who had intravenous administration of low dose of PGE1 (0.05-0.1 microgram.kg-1 x min-1, n = 10), NIC (1.0-5.0 micrograms.kg-1 x min-1, n = 10) and TNG (0.5-1.0 microgram.kg-1 x min-1, n = 10).	Alprostadil	172-176	CD59 molecule (CD59 blood group)	Homo sapiens	251-256
8164326-2	1994	The author measured blood gases, blood sugar, L/P, ATP, the deformability of red blood cell, 2,3-DPG, and P50 in patients who had intravenous administration of low dose of PGE1 (0.05-0.1 microgram.kg-1 x min-1, n = 10), NIC (1.0-5.0 micrograms.kg-1 x min-1, n = 10) and TNG (0.5-1.0 microgram.kg-1 x min-1, n = 10).	Alprostadil	172-176	CD59 molecule (CD59 blood group)	Homo sapiens	251-256
8164327-3	1994	PGE1 group was infused intravenously with PGE1 at a rate of 30 ng.kg-1 x min-1 during surgery and at a rate of 10-30 ng.kg-1 x min-1 after surgery.	Alprostadil	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
8164327-3	1994	PGE1 group was infused intravenously with PGE1 at a rate of 30 ng.kg-1 x min-1 during surgery and at a rate of 10-30 ng.kg-1 x min-1 after surgery.	Alprostadil	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
8164327-3	1994	PGE1 group was infused intravenously with PGE1 at a rate of 30 ng.kg-1 x min-1 during surgery and at a rate of 10-30 ng.kg-1 x min-1 after surgery.	Alprostadil	42-46	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
8164328-4	1994	Seven patients (PGE1 group) were given continuous infusion of PGE1 at a rate of 50 ng.kg-1 x min-1 after first measurement (baseline).	Alprostadil	16-20	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8164328-4	1994	Seven patients (PGE1 group) were given continuous infusion of PGE1 at a rate of 50 ng.kg-1 x min-1 after first measurement (baseline).	Alprostadil	62-66	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8139153-5	1994	Phosphatidyl-inositol (PI)-phospholipase C (PLC) reduced MACIF expression in these cells, suggesting that MACIF is a PI-linked membrane protein in GECs.	Phosphatidylinositols	0-21	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
8139153-5	1994	Phosphatidyl-inositol (PI)-phospholipase C (PLC) reduced MACIF expression in these cells, suggesting that MACIF is a PI-linked membrane protein in GECs.	Phosphatidylinositols	0-21	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
8304455-5	1994	Initial rate of RF uptake was temperature dependent and saturable as a function of concentration at 37 degrees C but not at 4 degrees C (apparent Michaelis constant = 0.30 +/- 0.03 microM, maximal velocity = 209.90 +/- 24.40 pmol.mg protein-1.3 min-1).	Riboflavin	16-18	CD59 molecule (CD59 blood group)	Homo sapiens	245-250
7872537-4	1994	Intubation avoiding respiratory depression: syringe pump with a fast infusion rate (50 to 100 mg.min-1), which allows induction with propofol and intubation without co-administration of muscle relaxants.	Propofol	133-141	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
7872542-11	1994	Atropine (0.02 mg.kg-1, possibly repeated) should be administered as soon as the heart rate decreases below 50 b.min-1.	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
7802545-3	1994	Cell suspensions catalyzed the reductive dechlorination of PCE with pyruvate as electron donor at specific rates of up to 150 nmol (chloride released) min-1 (mg cell protein)-1 (300 microM PCE initially, pH 7.5, 25 degrees C).	Tetrachloroethylene	59-62	CD59 molecule (CD59 blood group)	Homo sapiens	151-176
7802545-3	1994	Cell suspensions catalyzed the reductive dechlorination of PCE with pyruvate as electron donor at specific rates of up to 150 nmol (chloride released) min-1 (mg cell protein)-1 (300 microM PCE initially, pH 7.5, 25 degrees C).	Pyruvic Acid	68-76	CD59 molecule (CD59 blood group)	Homo sapiens	151-176
7802545-3	1994	Cell suspensions catalyzed the reductive dechlorination of PCE with pyruvate as electron donor at specific rates of up to 150 nmol (chloride released) min-1 (mg cell protein)-1 (300 microM PCE initially, pH 7.5, 25 degrees C).	Chlorides	132-140	CD59 molecule (CD59 blood group)	Homo sapiens	151-176
7802545-8	1994	Cell extracts mediated the dehalogenation of PCE and of TCE with reduced methyl viologen as the electron donor at specific rates of up to 0.5 mumol (chloride released) min-1 (mg protein).-1 An abiotic reductive dehalogenation could be excluded since cell extracts heated for 10 min at 95 degrees C were inactive.	Trichloroethylene	56-59	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
7802545-8	1994	Cell extracts mediated the dehalogenation of PCE and of TCE with reduced methyl viologen as the electron donor at specific rates of up to 0.5 mumol (chloride released) min-1 (mg protein).-1 An abiotic reductive dehalogenation could be excluded since cell extracts heated for 10 min at 95 degrees C were inactive.	Paraquat	73-88	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
7802545-8	1994	Cell extracts mediated the dehalogenation of PCE and of TCE with reduced methyl viologen as the electron donor at specific rates of up to 0.5 mumol (chloride released) min-1 (mg protein).-1 An abiotic reductive dehalogenation could be excluded since cell extracts heated for 10 min at 95 degrees C were inactive.	Chlorides	149-157	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
8166954-6	1994	In addition the sensor had a 90-99% response time of 1 min when used at a flow rate of 3 ml min-1 and showed a temperature dependence of 2.4% C-1.	Carbon	142-143	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
8110542-4	1994	All control oxygen responses were biphasic: the acute hypoxic response was 7.2 (4.6) litre min-1 and the subsequent decline 4.2 (2.6) litre min-1.	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
8110542-5	1994	With nitrous oxide, the acute hypoxic response was 10.3 (6.7) litre min-1, but was followed by a nonsignificant decline of 3.8 (3.0) litre min-1 because of a progressive increase in breathing frequency in the hypoxic period.	Nitrous Oxide	5-18	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
8110555-11	1994	Increasing isoflurane anaesthesia from 1 to 2 MAC increased mean CBF from 41 to 49 ml/100 g min-1 (P &lt; 0.01) and decreased mean CMRO2 from 1.5 to 1.1 ml/100 g min-1 (P &lt; 0.001) and thus abolished the coupling between flow and metabolism.	Isoflurane	11-21	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
8110555-11	1994	Increasing isoflurane anaesthesia from 1 to 2 MAC increased mean CBF from 41 to 49 ml/100 g min-1 (P &lt; 0.01) and decreased mean CMRO2 from 1.5 to 1.1 ml/100 g min-1 (P &lt; 0.001) and thus abolished the coupling between flow and metabolism.	Isoflurane	11-21	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
8148217-7	1994	Heart rate on treatment with lacidipine alone was significantly greater at 4 h compared with placebo (86 +/- 1 beats min-1 and 74 +/- 2 beats min-1 respectively; P &lt; 0.001).	lacidipine	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
8148217-7	1994	Heart rate on treatment with lacidipine alone was significantly greater at 4 h compared with placebo (86 +/- 1 beats min-1 and 74 +/- 2 beats min-1 respectively; P &lt; 0.001).	lacidipine	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
8148217-12	1994	Lacidipine alone produced a significant exercise tachycardia compared with atenolol alone and the atenolol/lacidipine combination (97 +/- 8 beats min-1; 65 +/- 4 beats min-1 and 75 +/- 7 beats min-1 respectively; P &lt; 0.001).	lacidipine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	168-180
8148217-12	1994	Lacidipine alone produced a significant exercise tachycardia compared with atenolol alone and the atenolol/lacidipine combination (97 +/- 8 beats min-1; 65 +/- 4 beats min-1 and 75 +/- 7 beats min-1 respectively; P &lt; 0.001).	Atenolol	98-106	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
8148217-12	1994	Lacidipine alone produced a significant exercise tachycardia compared with atenolol alone and the atenolol/lacidipine combination (97 +/- 8 beats min-1; 65 +/- 4 beats min-1 and 75 +/- 7 beats min-1 respectively; P &lt; 0.001).	Atenolol	98-106	CD59 molecule (CD59 blood group)	Homo sapiens	168-180
8148221-12	1994	For patients with early bone marrow toxicity the elimination half-life of ZDV was 1.10 +/- 0.16 h with an oral clearance of 2752 +/- 1031 ml min-1 compared with values of 1.06 +/- 0.18 h and 2843 +/- 730 ml min-1 seen in the control group.	Zidovudine	74-77	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
8148221-12	1994	For patients with early bone marrow toxicity the elimination half-life of ZDV was 1.10 +/- 0.16 h with an oral clearance of 2752 +/- 1031 ml min-1 compared with values of 1.06 +/- 0.18 h and 2843 +/- 730 ml min-1 seen in the control group.	Zidovudine	74-77	CD59 molecule (CD59 blood group)	Homo sapiens	207-212
8124580-7	1994	In control and parkinsonian substantia nigra DA oxidation rate constants were 2.82 x 10(-2) min-1 and 4.57 x 10(-2) min-1, respectively.	Dopamine	45-47	CD59 molecule (CD59 blood group)	Homo sapiens	92-103
8281647-6	1994	Maximal O2 uptake (VO2max) was 50.4 +/- 1.7 mL.kg-1 x min-1 in the MA and 29.6 +/- 1.4 mL.kg-1 x min-1 (P = .0001) in controls.	Oxygen	8-10	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
8306556-7	1994	Pretreatment glucose turnover rates [3.37 (2.57-4.16) mg min-1 kg-1] were comparable with those found in a previously reported study of non-pregnant severely ill patients [3.22 (2.12-4.82) mg min-1 kg-1, n = 11] and correlated significantly with the admission parasitaemia (P &lt; 0.025).	Glucose	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	57-67
8181249-2	1994	Creatinine excretion was 55% higher in men than women (geometric mean 8.9 mumol min-1 (95% confidence limits 4.7-17.0) compared with 5.7 (3.0-10.9); p &lt; 0.001).	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
8181249-5	1994	Likewise, the relationship between AER and albumin:creatinine ratio differed between men and women such that a ratio of 4.0 mg mmol-1 corresponded to a predicted AER of 35 micrograms min-1 in men and 23 micrograms min-1 in women.	Creatinine	51-61	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
7826649-7	1994	By avoiding volume overload (CVP &lt; or = 10 mmHg) at weaning off ECC and by lowering the systemic vascular resistance and, thus, LV afterload (approximately 8 micrograms.kg-1 min-1 dobutamine), the LV developed systemic pressure (70 +/- 7 vs. 41 +/- 4 mmHg) at unchanged diastolic LV end-diastolic pressure (LVedP) (10 +/- 3 mmHg).	Dobutamine	183-193	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
8117720-2	1994	Like p-nitrophenyl phosphate (pNPP), ANPP is hydrolyzed by the enzyme only in the presence of calcium and magnesium (K0.5 and Vmax are 0.3 mM and 60 nmol mg-1 min-1, respectively).	nitrophenylphosphate	5-28	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
7859804-9	1994	In patients with severe renal impairment (CLCR &lt; 10 ml.min-1), the glucuronides of oxcarbazepine and its monohydroxy-metabolite are likely to accumulate during repeated administration, and dosage adjustment of oxcarbazepine in these patients could not be proposed from this single administration study.	clcr	42-46	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
7859804-9	1994	In patients with severe renal impairment (CLCR &lt; 10 ml.min-1), the glucuronides of oxcarbazepine and its monohydroxy-metabolite are likely to accumulate during repeated administration, and dosage adjustment of oxcarbazepine in these patients could not be proposed from this single administration study.	Glucuronides	70-82	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
7859804-9	1994	In patients with severe renal impairment (CLCR &lt; 10 ml.min-1), the glucuronides of oxcarbazepine and its monohydroxy-metabolite are likely to accumulate during repeated administration, and dosage adjustment of oxcarbazepine in these patients could not be proposed from this single administration study.	Oxcarbazepine	86-99	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
7859804-9	1994	In patients with severe renal impairment (CLCR &lt; 10 ml.min-1), the glucuronides of oxcarbazepine and its monohydroxy-metabolite are likely to accumulate during repeated administration, and dosage adjustment of oxcarbazepine in these patients could not be proposed from this single administration study.	Oxcarbazepine	213-226	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
7957511-3	1994	infusion of a subsystemic dose (average 42 ng.min-1, SD 20.5) of noradrenaline in a dorsal hand vein was begun 1 h before drug treatment.	Norepinephrine	65-78	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
7957519-5	1994	The terminal disposition phase half-life of iopromide was 2 h and 1.9 h, and the total clearance was 110 and 103 ml.min-1 at the lower and at the higher dose levels, respectively.	iopromide	44-53	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
7957532-2	1994	Up to a rate of infusion of esmolol of 500 micrograms.kg-1 BW.min-1 there was a maximal beta 1-receptor occupancy of 84.7% while beta 2-receptor occupancy was below the detection limit; confirming the beta 1 selectivity of esmolol.	esmolol	28-35	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
7957532-2	1994	Up to a rate of infusion of esmolol of 500 micrograms.kg-1 BW.min-1 there was a maximal beta 1-receptor occupancy of 84.7% while beta 2-receptor occupancy was below the detection limit; confirming the beta 1 selectivity of esmolol.	esmolol	223-230	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8039538-10	1994	It is recommended that the dose of ranitidine is halved in patients with GFR &lt; or = 20 ml min-1.	Ranitidine	35-45	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8070507-2	1994	Ranitidine 150 mg.l-1 was perfused at 10 ml.min-1 for 180 min in different sites of the small intestine between 65-250 cm beyond the teeth.	Ranitidine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
8143834-4	1994	Budesonide was inhaled at a normal flow of 58 l.min-1 and at a slow flow of 36 l-min-1.	Budesonide	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
8143834-4	1994	Budesonide was inhaled at a normal flow of 58 l.min-1 and at a slow flow of 36 l-min-1.	Budesonide	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
8143834-6	1994	Mean lung deposition of terbutaline sulphate inhaled at 57 l.min-1 was 27.0 +/- 7.7%.	Terbutaline	24-44	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
8198831-4	1994	The apparent plasma half-life of ethylene glycol was 16 h and the mean renal and plasma clearances of ethylene glycol were 24 and 25 ml min-1, respectively.	Ethylene Glycol	102-117	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
8282375-3	1994	Intravenous infusion of isoproterenol at 0.02 microgram.kg-1 x min-1 for 30 minutes increased mean arterial pressure by 5 mm Hg (P &lt; .05), heart rate by 51 beats per minute (P &lt; .001), and plasma renin activity by 56% (P &lt; .001).	Isoproterenol	24-37	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
8282375-4	1994	Intravenous infusion of L-NAME at 0.5 mg.kg-1 x min-1 increased mean arterial pressure by 6 mm Hg (P &lt; .01) and decreased heart rate by 15 beats per minute (P &lt; .01) and plasma renin activity by 31% (P &lt; .05).	NG-Nitroarginine Methyl Ester	24-30	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
8282375-6	1994	Infusion of isoproterenol at 0.05 microgram.kg-1 x min-1 did not change blood pressure but increased heart rate by 62 beats per minute (P &lt; .001) and plasma renin activity by 283% (P &lt; .001).	Isoproterenol	12-25	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
8282375-8	1994	Intravenous infusion of the nitric oxide donor nitroprusside at 2 micrograms.kg-1.min-1 in the presence of L-NAME decreased mean arterial pressure by 7 mm Hg (P &lt; .05), increased heart rate by 14 beats per minute (P &lt; .05), but did not change plasma renin activity.	Nitric Oxide	28-40	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
8282375-8	1994	Intravenous infusion of the nitric oxide donor nitroprusside at 2 micrograms.kg-1.min-1 in the presence of L-NAME decreased mean arterial pressure by 7 mm Hg (P &lt; .05), increased heart rate by 14 beats per minute (P &lt; .05), but did not change plasma renin activity.	Nitroprusside	47-60	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
8282375-8	1994	Intravenous infusion of the nitric oxide donor nitroprusside at 2 micrograms.kg-1.min-1 in the presence of L-NAME decreased mean arterial pressure by 7 mm Hg (P &lt; .05), increased heart rate by 14 beats per minute (P &lt; .05), but did not change plasma renin activity.	NG-Nitroarginine Methyl Ester	107-113	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
8175515-3	1994	Plasma glucose levels were similar among all groups at all times during the trials; however, the glucose rates of appearance (Ra) at rest in CS (1.96 +/- 0.14 mg.kg-1 x min-1) and AS (2.02 +/- 0.14) were higher than in NS (1.41 +/- 0.15, P &lt; 0.05).	Glucose	97-104	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
8208448-10	1994	ATP was administered by an infusion pump at a dosage of 0.025-0.05 mg kg-1 min-1.	Adenosine Triphosphate	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
7800207-2	1994	The mean creatinine clearance at the beginning of the study was 89 +/- 13 ml/min/1.73 m2 in patients with type I and 81 +/- 6 ml/min/1.73 m2 in those with type II diabetes.	Creatinine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
7870353-4	1994	After CsA withdrawal the GFR increased, median from 74 ml min-1 to 90 ml min-1, (P &lt; 0.04).	Cyclosporine	6-9	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
7870353-4	1994	After CsA withdrawal the GFR increased, median from 74 ml min-1 to 90 ml min-1, (P &lt; 0.04).	Cyclosporine	6-9	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
8041965-4	1994	The creatinine clearance (mean +/- SD) of the patients was 81 +/- 6 mL/min/1.73 m2 at the beginning of the study.	Creatinine	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
7985515-4	1994	A mixture of acetonitrile and water (80: 20) as mobile phase was used at a flow rate of 1 ml.min-1.	acetonitrile	13-25	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
7985515-4	1994	A mixture of acetonitrile and water (80: 20) as mobile phase was used at a flow rate of 1 ml.min-1.	Water	30-35	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
8268182-1	1993	5-Ethynyluracil was shown to be a mechanism-based inactivator of thymine 7-hydroxylase, with Ki = 22 microM and a k2 = 2.6 min-1l Inactivation resulted in covalent modification of the enzyme with a stoichiometry of approximately 1 adduct/enzyme molecule.	eniluracil	0-15	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8267606-4	1993	However, 4 was found to be a mechanism-based (suicide) inactivator of 18H4 with a kinact of 0.29 min-1 and a K" of 64 microM.	18h4	70-74	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
7504951-5	1993	The purified cytoplasmic part of RPTP mu displays high activity toward tyrosine-phosphorylated, modified lysozyme (Vmax 4500 nmol min-1 mg-1) and myelin basic protein (Vmax 8500 nmol min-1 mg-1) but negligible activity toward tyrosine-phosphorylated angiotensin or the nonapeptide, EDNDpYINASL, that serves as a good substrate for protein tyrosine phosphatase PTP1B.	Tyrosine	71-79	CD59 molecule (CD59 blood group)	Homo sapiens	130-140
8128887-2	1993	Estimated maximal oxygen uptake was increased in the trained group when compared with the sedentary group (74.0 +/- 3.9 vs. 42.9 +/- 5.1 ml kg-1 min-1; P &lt; 0.01).	Oxygen	18-24	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
8128887-5	1993	The rate of insulin-stimulated glucose uptake was increased in the trained subjects (17.34 +/- 0.53 vs. 13.53 +/- 0.79 mg kg-1 min-1, P &lt; 0.01).	Glucose	31-38	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
8128891-10	1993	Yet, the arterial-coronary sinus (a-cs) lactate difference was lower during hypoxaemia than normoxaemia and isotope data indicated that this was caused by a myocardial lactate release of approximately 90 mumol min-1 which was at hand during hypoxaemia but not normoxaemia, whether hypoxaemic exercise preceded or succeeded normoxaemic exercise.	Lactic Acid	168-175	CD59 molecule (CD59 blood group)	Homo sapiens	210-215
7904127-5	1993	When Hep G2 cells were incubated in buffer, no GSH appeared in the medium over 2 h. However, after pretreatment with acivicin to inhibit gamma-glutamyl transpeptidase activity, GSH efflux was unmasked and measured 30 +/- 4 pmol x 10(6) cells-1 x min-1, which is comparable to rat hepatocytes.	acivicin	117-125	CD59 molecule (CD59 blood group)	Homo sapiens	246-251
7904127-9	1993	GSH uptake exhibited saturability with a maximal velocity of 4.15 +/- 0.23 nmol.mg-1 x 30 min-1, a Michaelis constant of 2.36 +/- 0.26 mM, and two interactive transport sites.	Glutathione	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
8267192-7	1993	RESULTS: The slope of the hypoxic ventilatory response curve (VE vs. SpO2) decreased from 0.88 +/- 0.15 to 0.17 +/- 0.03 l.min-1.%SpO2 -1 during propofol sedation (mean +/- SE).	Propofol	145-153	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8279535-4	1993	Palmitate flux decreased from 1.39 +/- 0.22 to 1.25 +/- 0.18 mumol.kg-1 x min-1 during sustained euglycemia and from 1.43 +/- 0.24 to 1.13 +/- 0.19 mumol.kg-1 x min-1 during the transition from the euglycemic to the hyperglycemic study intervals.	Palmitates	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
8279535-4	1993	Palmitate flux decreased from 1.39 +/- 0.22 to 1.25 +/- 0.18 mumol.kg-1 x min-1 during sustained euglycemia and from 1.43 +/- 0.24 to 1.13 +/- 0.19 mumol.kg-1 x min-1 during the transition from the euglycemic to the hyperglycemic study intervals.	Palmitates	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
8279537-4	1993	Glucose rate of appearance (Ra) declined equivalently in the 49 pmol.kg-1.min-1 IGF-I and insulin clamps but remained at basal levels during the 33 pmol.kg-1 x min-1 IGF-I infusions.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
8279537-4	1993	Glucose rate of appearance (Ra) declined equivalently in the 49 pmol.kg-1.min-1 IGF-I and insulin clamps but remained at basal levels during the 33 pmol.kg-1 x min-1 IGF-I infusions.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
8279537-5	1993	In contrast, Rd of glucose was increased by 176% in the 49 pmol.kg-1 x min-1 IGF-I and 78% in the 33 pmol.kg-1 x min-1 IGF-I infusions.	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
8279537-5	1993	In contrast, Rd of glucose was increased by 176% in the 49 pmol.kg-1 x min-1 IGF-I and 78% in the 33 pmol.kg-1 x min-1 IGF-I infusions.	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
8285322-7	1993	Thereafter requirements decreased: midazolam 0.065 (0.065) mg.min-1, propofol 2.1 (1.3) mg.min-1.	Propofol	69-77	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
8285329-6	1993	Only one patient required greater than 400 ml.min-1 of carbon dioxide to produce a 5% concentration.	Carbon Dioxide	55-69	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
8285329-7	1993	Maximum flow from the carbon dioxide flowmeter may be restricted to 400 ml.min-1 rather than the 500 ml.min-1 currently recommended.	Carbon Dioxide	22-36	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
8285335-5	1993	After operation, the effect of 4 l.min-1 of oxygen by nasal catheter on PaO2 was similar in all groups.	Oxygen	44-50	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
8267422-5	1993	Epinephrine (mean dose, 0.07 +/- 0.02 micrograms.kg-1.min-1) was administered via the central venous route, then via the left atrium, then via the central venous route again.	Epinephrine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
8280547-5	1993	administration, the clearance of pethidine was mean 10.4 (SD 1.7) ml kg-1 min-1, volume of distribution at steady state 2.8 (0.6) litre kg-1 and elimination half-life 3.0 (0.5) h. After rectal administration, plasma pethidine concentrations varied greatly and peak concentrations appeared late, at 147 (44) min.	Meperidine	33-42	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
8280548-7	1993	Mean intraoperative alfentanil requirement was greater in patients with Crohn"s disease (2.48 micrograms kg-1 min-1) than in control patients (1.35 micrograms kg-1 min-1) (P &lt; 0.01).	Alfentanil	20-30	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
8080489-11	1993	At the highest dose of methacholine, the forearm blood flow increased 9.5 +/- 1.1 mL x 100 mL-1 x min-1 in diabetic subjects and 15.3 +/- 1.4 mL.100 mL-1 x min-1 in normal subjects (P &lt; .01).	Methacholine Chloride	23-35	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
8080489-11	1993	At the highest dose of methacholine, the forearm blood flow increased 9.5 +/- 1.1 mL x 100 mL-1 x min-1 in diabetic subjects and 15.3 +/- 1.4 mL.100 mL-1 x min-1 in normal subjects (P &lt; .01).	Methacholine Chloride	23-35	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
8124056-3	1993	Neutrophils were obtained at various time points before, during, and after infusion of L-arginine (17 mg kg-1 min-1 for 30 min) and analyzed for superoxide dismutase inhibitable reduction of ferricytochrome c. The spontaneously occurring respiratory burst of polymorphonuclear leukocytes at basal conditions was compared with that after triggering by 1 mumol/l formylpeptide or 50 ng/ml phorbolester.	Arginine	87-97	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
8287659-6	1993	Indomethacin administration resulted in an increase in glucose production from 10.9 (SEM 0.3) mumol min-1 kg-1 to a maximum of 16.5 (SEM 1.6) mumol min-1 kg-1 (P &lt; 0.05) within approximately 1 h, whereas in the control experiment glucose production declined gradually (P &lt; 0.01) (P &lt; 0.05 indomethacin versus control).	Indomethacin	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	100-110
8287659-6	1993	Indomethacin administration resulted in an increase in glucose production from 10.9 (SEM 0.3) mumol min-1 kg-1 to a maximum of 16.5 (SEM 1.6) mumol min-1 kg-1 (P &lt; 0.05) within approximately 1 h, whereas in the control experiment glucose production declined gradually (P &lt; 0.01) (P &lt; 0.05 indomethacin versus control).	Indomethacin	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	148-158
8287659-6	1993	Indomethacin administration resulted in an increase in glucose production from 10.9 (SEM 0.3) mumol min-1 kg-1 to a maximum of 16.5 (SEM 1.6) mumol min-1 kg-1 (P &lt; 0.05) within approximately 1 h, whereas in the control experiment glucose production declined gradually (P &lt; 0.01) (P &lt; 0.05 indomethacin versus control).	Glucose	55-62	CD59 molecule (CD59 blood group)	Homo sapiens	100-110
8243814-7	1993	Gluconeogenesis from lactate decreased by approximately 40%, from 6.2 +/- 0.6 to 3.8 +/- 0.5 mumol.kg-1 x min-1 (P &lt; 0.005); lactate oxidation increased from 5.6 +/- 0.8 to 7.9 +/- 1.1 mumol.kg-1 x min-1 (P &lt; 0.005), with no change in plasma lactate concentrations or total lactate Rd.	Lactic Acid	21-28	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
8243814-7	1993	Gluconeogenesis from lactate decreased by approximately 40%, from 6.2 +/- 0.6 to 3.8 +/- 0.5 mumol.kg-1 x min-1 (P &lt; 0.005); lactate oxidation increased from 5.6 +/- 0.8 to 7.9 +/- 1.1 mumol.kg-1 x min-1 (P &lt; 0.005), with no change in plasma lactate concentrations or total lactate Rd.	Lactic Acid	21-28	CD59 molecule (CD59 blood group)	Homo sapiens	201-206
8287854-6	1993	The average ventilation rate at this workload is below 25 l.min-1, with predicted inspiratory mouth pressure equal to, or less than, 20 mm H2O.	Water	139-142	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
8306591-6	1993	Inhibition of NEFA metabolism was associated with increased insulin-stimulated glucose uptake (from 3.56 +/- 0.28 to 5.14 +/- 0.67 mumol kg-1 min-1, p &lt; 0.05), mainly due to stimulation of non-oxidative glucose disposal (from 1.74 +/- 0.23 to 3.03 +/- 0.53 mumol kg-1 min-1, p &lt; 0.05).	Glucose	79-86	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
8306591-6	1993	Inhibition of NEFA metabolism was associated with increased insulin-stimulated glucose uptake (from 3.56 +/- 0.28 to 5.14 +/- 0.67 mumol kg-1 min-1, p &lt; 0.05), mainly due to stimulation of non-oxidative glucose disposal (from 1.74 +/- 0.23 to 3.03 +/- 0.53 mumol kg-1 min-1, p &lt; 0.05).	Glucose	79-86	CD59 molecule (CD59 blood group)	Homo sapiens	271-276
8123998-10	1993	The DS had a significantly (P = 0.006) lower peak oxygen uptake (ml kg-1 min-1) as compared to the NDS group (23.68 +/- 4.01 vs 31.00 +/- 7.11, respectively).	Oxygen	50-56	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
8301937-9	1993	On the other hand, protein-bound tryptophan varies with protein intake, decreases markedly in hypoalbuminemic patients, and also decreases in many nonhypoalbuminemic patients (especially females) when the glomerular filtration rate falls below approximately 30 ml/min/3 m2 of height2.	Tryptophan	33-43	CD59 molecule (CD59 blood group)	Homo sapiens	264-269
7859804-3	1994	The mean areas under the plasma concentration-time curves of oxcarbazepine and its monohydroxy-metabolite were 2-2.5-times higher in patients with severe renal impairment (CLCR &lt; 10 ml.min-1) than in healthy subjects.	Oxcarbazepine	61-74	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
7507750-0	1993	Sequence-specific 1H-NMR assignments and folding topology of human CD59.	Hydrogen	18-20	CD59 molecule (CD59 blood group)	Homo sapiens	67-71
8108197-4	1993	The rate of urea synthesis in normal infants was 5.84 +/- 2.0 mg of nitrogen (N)/kg.h-1 or 3.5 mumol of urea/kg.min-1.	Urea	12-16	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
8135043-6	1993	In human liver, the mean (+/- SD) and coefficient of variation for the formation rate of benzoyl glycine were 254 +/- 90.5 nmol min-1 per g liver and 36%, respectively.	hippuric acid	89-104	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
8108197-7	1993	The rate of appearance of glucose was lower in IDM infants studied during the first 6 h after birth (IDM 19.62 +/- 2.14 mumol/kg.min-1, normal infants 24.03 +/- 4.05 mumol/kg.min-1, p = 0.01).	Glucose	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
8108197-7	1993	The rate of appearance of glucose was lower in IDM infants studied during the first 6 h after birth (IDM 19.62 +/- 2.14 mumol/kg.min-1, normal infants 24.03 +/- 4.05 mumol/kg.min-1, p = 0.01).	Glucose	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	175-180
8108197-9	1993	Rate of appearance of glucose was lower (not significantly) in SGA infants (17.7 +/- 3.3 mumol/kg.min-1) as compared with normal infants.	Glucose	22-29	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
8250859-7	1993	Propylthiouracil also inactivates GPO activity in the same manner but its efficiency (k(inact./ki = 0.46 mM-1 x min-1) is about 10 times lower than that of MMI (k(inact./ki = 5 mM-1 x min-1).	Propylthiouracil	0-16	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
8250859-7	1993	Propylthiouracil also inactivates GPO activity in the same manner but its efficiency (k(inact./ki = 0.46 mM-1 x min-1) is about 10 times lower than that of MMI (k(inact./ki = 5 mM-1 x min-1).	Propylthiouracil	0-16	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
8238506-2	1993	The rates of appearance (Ra) of glycerol and palmitic acid in plasma doubled from 2.08 +/- 0.22 and 1.63 +/- 0.20 mumol.kg-1 x min-1, respectively, after 12 h to 4.36 +/- 0.36 and 3.26 +/- 0.40 mumol.kg-1 x min-1, respectively, after 72 h of fasting (P &lt; 0.01).	Radium	25-27	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
8238493-6	1993	Hepatic glucose production was increased during the high-compared with low-dose infusions (9.5 +/- 1.1 vs. 5.1 +/- 2.2 mumol.kg-1 x min-1; P &lt; 0.05).	Glucose	8-15	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
8238506-2	1993	The rates of appearance (Ra) of glycerol and palmitic acid in plasma doubled from 2.08 +/- 0.22 and 1.63 +/- 0.20 mumol.kg-1 x min-1, respectively, after 12 h to 4.36 +/- 0.36 and 3.26 +/- 0.40 mumol.kg-1 x min-1, respectively, after 72 h of fasting (P &lt; 0.01).	Radium	25-27	CD59 molecule (CD59 blood group)	Homo sapiens	207-212
8238498-2	1993	Net fetal glutamine uptake (Fick principle, antipyrine blood flow) was 10.0 +/- 2.0 mumol.kg-1 x min-1 in fed fetuses and 6.4 +/- 1.4 mumol.kg-1 x min-1 in fasted fetuses [not significant (NS)].	Glutamine	10-19	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
8238498-4	1993	In contrast, fetal glutamate transfer to the placenta was 4.0 +/- 0.8 mumol.kg-1.min-1 in the fed state and 2.7 +/- 0.1 mumol.kg-1 x min-1 in the fasted state.	Glutamic Acid	19-28	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
8238506-2	1993	The rates of appearance (Ra) of glycerol and palmitic acid in plasma doubled from 2.08 +/- 0.22 and 1.63 +/- 0.20 mumol.kg-1 x min-1, respectively, after 12 h to 4.36 +/- 0.36 and 3.26 +/- 0.40 mumol.kg-1 x min-1, respectively, after 72 h of fasting (P &lt; 0.01).	Glycerol	32-40	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
8238498-4	1993	In contrast, fetal glutamate transfer to the placenta was 4.0 +/- 0.8 mumol.kg-1.min-1 in the fed state and 2.7 +/- 0.1 mumol.kg-1 x min-1 in the fasted state.	Glutamic Acid	19-28	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
8238506-2	1993	The rates of appearance (Ra) of glycerol and palmitic acid in plasma doubled from 2.08 +/- 0.22 and 1.63 +/- 0.20 mumol.kg-1 x min-1, respectively, after 12 h to 4.36 +/- 0.36 and 3.26 +/- 0.40 mumol.kg-1 x min-1, respectively, after 72 h of fasting (P &lt; 0.01).	Glycerol	32-40	CD59 molecule (CD59 blood group)	Homo sapiens	207-212
8238506-2	1993	The rates of appearance (Ra) of glycerol and palmitic acid in plasma doubled from 2.08 +/- 0.22 and 1.63 +/- 0.20 mumol.kg-1 x min-1, respectively, after 12 h to 4.36 +/- 0.36 and 3.26 +/- 0.40 mumol.kg-1 x min-1, respectively, after 72 h of fasting (P &lt; 0.01).	Palmitic Acid	45-58	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
8238506-2	1993	The rates of appearance (Ra) of glycerol and palmitic acid in plasma doubled from 2.08 +/- 0.22 and 1.63 +/- 0.20 mumol.kg-1 x min-1, respectively, after 12 h to 4.36 +/- 0.36 and 3.26 +/- 0.40 mumol.kg-1 x min-1, respectively, after 72 h of fasting (P &lt; 0.01).	Palmitic Acid	45-58	CD59 molecule (CD59 blood group)	Homo sapiens	207-212
8215437-2	1993	These cells decarboxylated added oxaloacetate to PEP at rates exceeding 2.5 mumol min-1 mg-1 chlorophyll when ATP was added.	Oxaloacetic Acid	33-45	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
8215437-2	1993	These cells decarboxylated added oxaloacetate to PEP at rates exceeding 2.5 mumol min-1 mg-1 chlorophyll when ATP was added.	Chlorophyll	93-104	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
8215437-2	1993	These cells decarboxylated added oxaloacetate to PEP at rates exceeding 2.5 mumol min-1 mg-1 chlorophyll when ATP was added.	Adenosine Triphosphate	110-113	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
8215437-8	1993	When malate was added with oxaloacetate, ADP and Pi rates of malate decarboxylation of between 3 and 4 mumol min-1 mg-1 chlorophyll were recorded.	malic acid	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
8215437-8	1993	When malate was added with oxaloacetate, ADP and Pi rates of malate decarboxylation of between 3 and 4 mumol min-1 mg-1 chlorophyll were recorded.	Oxaloacetic Acid	27-39	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
8215437-8	1993	When malate was added with oxaloacetate, ADP and Pi rates of malate decarboxylation of between 3 and 4 mumol min-1 mg-1 chlorophyll were recorded.	malic acid	61-67	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
8215437-8	1993	When malate was added with oxaloacetate, ADP and Pi rates of malate decarboxylation of between 3 and 4 mumol min-1 mg-1 chlorophyll were recorded.	Chlorophyll	120-131	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
7692919-2	1993	CD59, a phosphatidyl-inositol-anchored glycoprotein, inhibits the formation of the terminal membrane attack complex (MAC) of complement and was found to be a second ligand for CD2 contributing to T-cell activation.	Phosphatidylinositols	8-29	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
7694573-0	1993	Expression of the glycosylphosphatidylinositol-linked complement-inhibiting protein CD59 antigen in insect cells using a baculovirus vector.	Glycosylphosphatidylinositols	18-46	CD59 molecule (CD59 blood group)	Homo sapiens	84-88
7694573-1	1993	CD59 antigen (CD59) is a glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein which protects human cells from complement-mediated lysis.	Glycosylphosphatidylinositols	25-53	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
7694573-1	1993	CD59 antigen (CD59) is a glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein which protects human cells from complement-mediated lysis.	Glycosylphosphatidylinositols	25-53	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
7694573-1	1993	CD59 antigen (CD59) is a glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein which protects human cells from complement-mediated lysis.	Glycosylphosphatidylinositols	55-58	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
7694573-1	1993	CD59 antigen (CD59) is a glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein which protects human cells from complement-mediated lysis.	Glycosylphosphatidylinositols	55-58	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
7905337-7	1993	Net celiprolol secretion obtained in the concentration range 0.01 to 5 mM displayed saturable kinetics with an apparent Km of 1.00 +/- 0.23 mM and Vmax of 113 +/- 11 pmol/10(6) cells min-1.	Celiprolol	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
8287414-8	1993	When adenosine was given, coronary blood flow and coronary vascular conductance were increased to similar degrees as those during reactive hyperaemia (41(12) to 210(75) ml.min-1 and 0.46(0.14) to 2.43(0.83) mm Hg.ml-1.min-1, respectively; NS).	Adenosine	5-14	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
8251271-4	1993	In the presence of 0.1% inspired halothane, ventilation increased initially from 7.19 (0.47) litre min-1 to 12.08 (0.99) litre min-1 (P &lt; 0.05), then decreased to 10.12 (0.28) litre min-1 during sustained hypoxia (ns compared with baseline normoxic ventilation).	Halothane	33-42	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
8251271-4	1993	In the presence of 0.1% inspired halothane, ventilation increased initially from 7.19 (0.47) litre min-1 to 12.08 (0.99) litre min-1 (P &lt; 0.05), then decreased to 10.12 (0.28) litre min-1 during sustained hypoxia (ns compared with baseline normoxic ventilation).	Halothane	33-42	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
8251271-4	1993	In the presence of 0.1% inspired halothane, ventilation increased initially from 7.19 (0.47) litre min-1 to 12.08 (0.99) litre min-1 (P &lt; 0.05), then decreased to 10.12 (0.28) litre min-1 during sustained hypoxia (ns compared with baseline normoxic ventilation).	Halothane	33-42	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
8287414-8	1993	When adenosine was given, coronary blood flow and coronary vascular conductance were increased to similar degrees as those during reactive hyperaemia (41(12) to 210(75) ml.min-1 and 0.46(0.14) to 2.43(0.83) mm Hg.ml-1.min-1, respectively; NS).	Adenosine	5-14	CD59 molecule (CD59 blood group)	Homo sapiens	218-223
8405695-2	1993	During acipimox treatment, serum free fatty acid concentrations were suppressed between 2400 and 0600 by 64% (P &lt; 0.001), but no reduction in hepatic glucose production was observed (2.16 +/- 0.16 vs. 2.23 +/- 0.16 mg.kg-1 x min-1, acipimox vs. placebo).	acipimox	7-15	CD59 molecule (CD59 blood group)	Homo sapiens	228-233
8405699-2	1993	During basal conditions, 5.6 +/- 0.6 mumol.kg-1 x min-1 of fatty acid were released of which approximately 3.3 mumol.kg-1 x min-1 were oxidized and approximately 2.2 mumol.kg-1 x min-1 were reesterified.	Fatty Acids	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
8405699-2	1993	During basal conditions, 5.6 +/- 0.6 mumol.kg-1 x min-1 of fatty acid were released of which approximately 3.3 mumol.kg-1 x min-1 were oxidized and approximately 2.2 mumol.kg-1 x min-1 were reesterified.	Fatty Acids	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
8405699-2	1993	During basal conditions, 5.6 +/- 0.6 mumol.kg-1 x min-1 of fatty acid were released of which approximately 3.3 mumol.kg-1 x min-1 were oxidized and approximately 2.2 mumol.kg-1 x min-1 were reesterified.	Fatty Acids	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
8405699-3	1993	A minority of the recycled fatty acid, (0.8 +/- 0.4 mumol.kg-1 x min-1) never left the intracellular space before being reesterified (intracellular triacylglycerol/fatty acid cycling), whereas the majority (1.2 +/- 0.4 mumol.kg-1 x min-1) were first released into the extracellular space and then reesterified in various organs (extracellular triacylglycerol/fatty acid cycling).	Fatty Acids	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
8405699-3	1993	A minority of the recycled fatty acid, (0.8 +/- 0.4 mumol.kg-1 x min-1) never left the intracellular space before being reesterified (intracellular triacylglycerol/fatty acid cycling), whereas the majority (1.2 +/- 0.4 mumol.kg-1 x min-1) were first released into the extracellular space and then reesterified in various organs (extracellular triacylglycerol/fatty acid cycling).	Fatty Acids	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	232-237
8405699-4	1993	In response to insulin, fatty acid release declined by 71% (from 5.6 +/- 0.6 to 1.6 +/- 0.2 mumol.kg-1 x min-1).	Fatty Acids	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
8405699-5	1993	Fatty acid oxidation (measured by indirect calorimetry) declined by 55% (from 3.3 +/- 0.3 to 1.5 +/- 0.3 mumol.kg-1 x min-1) and total triacylglycerol/fatty acid cycling was completely suppressed (from 2.2 to 0.0 mumol.kg-1 x min-1).	Fatty Acids	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
8405699-5	1993	Fatty acid oxidation (measured by indirect calorimetry) declined by 55% (from 3.3 +/- 0.3 to 1.5 +/- 0.3 mumol.kg-1 x min-1) and total triacylglycerol/fatty acid cycling was completely suppressed (from 2.2 to 0.0 mumol.kg-1 x min-1).	Fatty Acids	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	226-231
8405705-13	1993	Plasma glucose rate of disappearance was significantly increased by alcohol intake in IDDM (13.72 +/- 0.82 vs. 11.84 +/- 0.53 mumol.kg-1 x min-1; P &lt; 0.05).	Glucose	7-14	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
8405705-13	1993	Plasma glucose rate of disappearance was significantly increased by alcohol intake in IDDM (13.72 +/- 0.82 vs. 11.84 +/- 0.53 mumol.kg-1 x min-1; P &lt; 0.05).	Alcohols	68-75	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
8112441-6	1993	After treatment with bambuterol, mean morning and evening PEF (SD) were 347 (122) and 365 (121) l.min-1, respectively and 346 (121) and 365 (122) l.min-1, respectively, after treatment with terbutaline.	bambuterol	21-31	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
8112441-6	1993	After treatment with bambuterol, mean morning and evening PEF (SD) were 347 (122) and 365 (121) l.min-1, respectively and 346 (121) and 365 (122) l.min-1, respectively, after treatment with terbutaline.	bambuterol	21-31	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
8112441-6	1993	After treatment with bambuterol, mean morning and evening PEF (SD) were 347 (122) and 365 (121) l.min-1, respectively and 346 (121) and 365 (122) l.min-1, respectively, after treatment with terbutaline.	Terbutaline	190-201	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
8223854-3	1993	In granulocytes primed with 200 mM N-formyl-Met-Leu-Phe (FMLP), cross-linking of cell-bound anti-CD16, -CD24, -CD59 and -CD67 led to calcium fluxes and activation of the oxidative burst.	N-Formylmethionine Leucyl-Phenylalanine	35-55	CD59 molecule (CD59 blood group)	Homo sapiens	111-115
8223854-3	1993	In granulocytes primed with 200 mM N-formyl-Met-Leu-Phe (FMLP), cross-linking of cell-bound anti-CD16, -CD24, -CD59 and -CD67 led to calcium fluxes and activation of the oxidative burst.	Calcium	133-140	CD59 molecule (CD59 blood group)	Homo sapiens	111-115
8299636-6	1993	Time averaged flow, calculated from mean velocity and the cross-sectional area of the vessels was 4.99 +/- 1.10 l.min-1 in MPA, 2.23 +/- 0.58 l.min-1 in RPA and 2.31 +/- 0.63 l.min-1 in LPA.	lpa	186-189	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
11767317-2	1993	The patients in the pre-oxgenated group (n = 30) received 8 litre min-1 oxygen through a plastic facemask for 3 min whereas those in a control group (n = 30) were not pre-oxygenated.	Oxygen	72-78	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
11767317-7	1993	An 8 litre min-1 oxygen flow via a standard transparent plastic facemask is a simple, feasible and acceptable method for routine pre-oxygenation for all elective cases.	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	11-16
7691457-6	1993	MCP, DAF, and CD59 were observed in EVT.	EVT	36-39	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
8227141-5	1993	GTP hydrolysis by SRP was not detected, so the maximal GTP hydrolysis rate for SRP was estimated to be &lt; 0.002 mol GTP hydrolyzed x mol of SRP-1 x min-1.	Guanosine Triphosphate	55-58	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
8227141-5	1993	GTP hydrolysis by SRP was not detected, so the maximal GTP hydrolysis rate for SRP was estimated to be &lt; 0.002 mol GTP hydrolyzed x mol of SRP-1 x min-1.	Guanosine Triphosphate	55-58	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
8227141-6	1993	The intrinsic GTP hydrolysis activity of the SRP receptor ranged between 0.02 and 0.04 mol GTP hydrolyzed x mol of SRP receptor-1 x min-1.	Guanosine Triphosphate	14-17	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
8227141-6	1993	The intrinsic GTP hydrolysis activity of the SRP receptor ranged between 0.02 and 0.04 mol GTP hydrolyzed x mol of SRP receptor-1 x min-1.	Guanosine Triphosphate	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
8290741-5	1993	Compared to placebo, bambuterol produced a 16% improvement in mean PEF on waking (271 l min-1 vs. 239 l min-1 P = 0.0002) and a 10% improvement in evening PEF measured 24 h after drug intake (318 l min-1 vs. 296 l min-1 P = 0.01).	bambuterol	21-31	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
7691959-2	1993	Human CD59-Ag is a glycophosphoinositol lipid-anchored inhibitor of the membrane attack complex of complement (MAC).	glycophosphoinositol lipid	19-45	CD59 molecule (CD59 blood group)	Homo sapiens	6-10
8120827-13	1993	The skeletal muscle dialysate lactate concentration (1 microliter min-1: 1.16 +/- 0.2 mM) was higher than in adipose tissue (0.76 +/- 0.08 mM, P &lt; 0.05), where the absolute amount of lactate that could be removed from the tissue (at 4 microliters min-1) was only half of that in skeletal muscle (0.8 +/- 0.11 vs. 1.76 +/- 0.23 nmol min-1, P &lt; 0.05).	Lactic Acid	30-37	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
8254878-4	1993	Continuous infusion of prostaglandin E1 0.05-0.10 microgram.kg-1 x min-1 and bolus infusion of 7.0% NaHCO3 during the operation were useful in controlling blood pressure, improving hyperkalemia and maintaining renal function.	Alprostadil	23-39	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
8117632-7	1993	CO2-response curve slopes decreased from 1.84 +/- 0.54 to 1.40 +/- 0.58 l/min-1.mm Hg-1 (p &lt; 0.05), and the curves were displaced 3.2 +/- 1.2 mm Hg to the right at 25 l/min-1 VE (p &lt; 0.05).	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
8117632-7	1993	CO2-response curve slopes decreased from 1.84 +/- 0.54 to 1.40 +/- 0.58 l/min-1.mm Hg-1 (p &lt; 0.05), and the curves were displaced 3.2 +/- 1.2 mm Hg to the right at 25 l/min-1 VE (p &lt; 0.05).	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
8290741-5	1993	Compared to placebo, bambuterol produced a 16% improvement in mean PEF on waking (271 l min-1 vs. 239 l min-1 P = 0.0002) and a 10% improvement in evening PEF measured 24 h after drug intake (318 l min-1 vs. 296 l min-1 P = 0.01).	bambuterol	21-31	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
8290741-5	1993	Compared to placebo, bambuterol produced a 16% improvement in mean PEF on waking (271 l min-1 vs. 239 l min-1 P = 0.0002) and a 10% improvement in evening PEF measured 24 h after drug intake (318 l min-1 vs. 296 l min-1 P = 0.01).	bambuterol	21-31	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
8290741-5	1993	Compared to placebo, bambuterol produced a 16% improvement in mean PEF on waking (271 l min-1 vs. 239 l min-1 P = 0.0002) and a 10% improvement in evening PEF measured 24 h after drug intake (318 l min-1 vs. 296 l min-1 P = 0.01).	bambuterol	21-31	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
8290745-5	1993	Fluticasone propionate via the Diskhaler was significantly more effective than beclomethasone dipropionate over the 6 week study period in reducing diurnal variation (mean difference--4 l min-1, 95% CI--8 to 0 l min-1: P = 0.03).	Fluticasone	0-22	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
8290745-5	1993	Fluticasone propionate via the Diskhaler was significantly more effective than beclomethasone dipropionate over the 6 week study period in reducing diurnal variation (mean difference--4 l min-1, 95% CI--8 to 0 l min-1: P = 0.03).	Fluticasone	0-22	CD59 molecule (CD59 blood group)	Homo sapiens	212-217
8222031-9	1993	The P/N2O group (255 +/- 80 micrograms.kg-1 x min-1) received less propofol than the P/O2 group (344 +/- 60 micrograms.kg-1 x min-1) (P &lt; or = 0.0001) and had shorter extubation (P &lt; 0.001) and recovery (P &lt; 0.01) times.	Phosphorus	4-5	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
8242228-14	1993	In platelet membranes at 37 degrees C, specific [3H]-GR32191 binding was complete within 5 min with a calculated association rate constant of 3.2 x 10(8) M-1 min-1.	Tritium	49-51	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
8242245-4	1993	Acetylcholine (83 nmol min-1) infused into the brachial artery of 8 healthy volunteers caused a submaximal increase in forearm blood flow, measured by venous occlusion plethysmography, from 3.3 +/- 0.5 (mean +/- s.e.	Acetylcholine	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	23-28
8242245-7	1993	Co-infusion of L-NMMA (4 mumol min-1) with acetylcholine (83 nmol min-1) over 6 min resulted in a 58% +/- 12% fall in the response to acetylcholine whereas during co-infusion of saline over the same time period in the same subjects (n = 8) on a different day the response to acetylcholine fell by only 9% +/- 17% (P &lt; 0.01).	omega-N-Methylarginine	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
8242245-7	1993	Co-infusion of L-NMMA (4 mumol min-1) with acetylcholine (83 nmol min-1) over 6 min resulted in a 58% +/- 12% fall in the response to acetylcholine whereas during co-infusion of saline over the same time period in the same subjects (n = 8) on a different day the response to acetylcholine fell by only 9% +/- 17% (P &lt; 0.01).	omega-N-Methylarginine	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
8242245-7	1993	Co-infusion of L-NMMA (4 mumol min-1) with acetylcholine (83 nmol min-1) over 6 min resulted in a 58% +/- 12% fall in the response to acetylcholine whereas during co-infusion of saline over the same time period in the same subjects (n = 8) on a different day the response to acetylcholine fell by only 9% +/- 17% (P &lt; 0.01).	Acetylcholine	43-56	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
8242245-7	1993	Co-infusion of L-NMMA (4 mumol min-1) with acetylcholine (83 nmol min-1) over 6 min resulted in a 58% +/- 12% fall in the response to acetylcholine whereas during co-infusion of saline over the same time period in the same subjects (n = 8) on a different day the response to acetylcholine fell by only 9% +/- 17% (P &lt; 0.01).	Acetylcholine	43-56	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
8242245-7	1993	Co-infusion of L-NMMA (4 mumol min-1) with acetylcholine (83 nmol min-1) over 6 min resulted in a 58% +/- 12% fall in the response to acetylcholine whereas during co-infusion of saline over the same time period in the same subjects (n = 8) on a different day the response to acetylcholine fell by only 9% +/- 17% (P &lt; 0.01).	Acetylcholine	134-147	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
8242245-7	1993	Co-infusion of L-NMMA (4 mumol min-1) with acetylcholine (83 nmol min-1) over 6 min resulted in a 58% +/- 12% fall in the response to acetylcholine whereas during co-infusion of saline over the same time period in the same subjects (n = 8) on a different day the response to acetylcholine fell by only 9% +/- 17% (P &lt; 0.01).	Acetylcholine	134-147	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
8242245-7	1993	Co-infusion of L-NMMA (4 mumol min-1) with acetylcholine (83 nmol min-1) over 6 min resulted in a 58% +/- 12% fall in the response to acetylcholine whereas during co-infusion of saline over the same time period in the same subjects (n = 8) on a different day the response to acetylcholine fell by only 9% +/- 17% (P &lt; 0.01).	Sodium Chloride	178-184	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
8242245-7	1993	Co-infusion of L-NMMA (4 mumol min-1) with acetylcholine (83 nmol min-1) over 6 min resulted in a 58% +/- 12% fall in the response to acetylcholine whereas during co-infusion of saline over the same time period in the same subjects (n = 8) on a different day the response to acetylcholine fell by only 9% +/- 17% (P &lt; 0.01).	Sodium Chloride	178-184	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
8242245-7	1993	Co-infusion of L-NMMA (4 mumol min-1) with acetylcholine (83 nmol min-1) over 6 min resulted in a 58% +/- 12% fall in the response to acetylcholine whereas during co-infusion of saline over the same time period in the same subjects (n = 8) on a different day the response to acetylcholine fell by only 9% +/- 17% (P &lt; 0.01).	Acetylcholine	134-147	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
8242245-7	1993	Co-infusion of L-NMMA (4 mumol min-1) with acetylcholine (83 nmol min-1) over 6 min resulted in a 58% +/- 12% fall in the response to acetylcholine whereas during co-infusion of saline over the same time period in the same subjects (n = 8) on a different day the response to acetylcholine fell by only 9% +/- 17% (P &lt; 0.01).	Acetylcholine	134-147	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
8242245-9	1993	Methacholine (1.5 and 15 nmol min-1) increased forearm blood flow from 2.5 +/- 0.4 to 5.9 +/- 0.9 and from 3.2 +/- 0.4 to 17.0 +/- 1.9 ml min-1 100 ml-1 respectively.	Methacholine Chloride	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
8242245-9	1993	Methacholine (1.5 and 15 nmol min-1) increased forearm blood flow from 2.5 +/- 0.4 to 5.9 +/- 0.9 and from 3.2 +/- 0.4 to 17.0 +/- 1.9 ml min-1 100 ml-1 respectively.	Methacholine Chloride	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
8242245-12	1993	Co-infusion of a higher dose of L-NMMA (8 mumol min-1) with methacholine (1.5 nmol min-1) did not significantly inhibit the vasodilator response (n = 7).	omega-N-Methylarginine	32-38	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
8242257-5	1993	dose of 15 mg (about 319 micrograms kg-1) of captopril to salt-replete ewes followed by an infusion to the ewe of 6 mg h-1 (about 128 micrograms kg-1 h-1) caused a fall in fetal arterial pressure (P &lt; 0.01), and a rise in fetal renal blood flow (RBF) from 67.9 +/- 5.6 to 84.9 +/- 8.3 ml min-1 (mean +/- s.e.	Captopril	45-54	CD59 molecule (CD59 blood group)	Homo sapiens	291-296
8403299-11	1993	APA and CPA were totally inhibited at the end of infusion of 0.4 microgram.kg-1 x min-1 and returned to 55% and 89% of baseline, respectively, at 3 hours after infusion.	apa	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
8222508-9	1993	Whole-body insulin sensitivity was 10.5 +/- 2 mg of glucose min-1kg-1 after placebo, and 10.5 +/- 2.2 and 10.9 +/- 3.4 mg of glucose min-1kg-1 after low and high dose angiotensin II (not significant).	Glucose	125-132	CD59 molecule (CD59 blood group)	Homo sapiens	133-142
8222512-8	1993	for aspirin-sensitive asthmatic patients [15.9 (SD 6.9) nmol min-1 mg-1 of protein] was not significantly different from that for the normal subjects.	Aspirin	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	61-71
8222516-4	1993	Noradrenaline infusion rates ranged from 0.015 to 0.075 microgram min-1 kg-1.	Norepinephrine	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	66-76
7691609-3	1993	In this study we observed that the surface expression of CD59 on the cultured EA.hy 926 endothelial cell line can be up-regulated to an approximately threefold higher level after a 72-h stimulation by the protein kinase C inducers phorbol-12-myristate-13 acetate (PMA; 10 nM) and calcium ionophore, A23187 (100 nM).	Tetradecanoylphorbol Acetate	231-262	CD59 molecule (CD59 blood group)	Homo sapiens	57-61
7691609-3	1993	In this study we observed that the surface expression of CD59 on the cultured EA.hy 926 endothelial cell line can be up-regulated to an approximately threefold higher level after a 72-h stimulation by the protein kinase C inducers phorbol-12-myristate-13 acetate (PMA; 10 nM) and calcium ionophore, A23187 (100 nM).	Tetradecanoylphorbol Acetate	264-267	CD59 molecule (CD59 blood group)	Homo sapiens	57-61
7691609-3	1993	In this study we observed that the surface expression of CD59 on the cultured EA.hy 926 endothelial cell line can be up-regulated to an approximately threefold higher level after a 72-h stimulation by the protein kinase C inducers phorbol-12-myristate-13 acetate (PMA; 10 nM) and calcium ionophore, A23187 (100 nM).	Calcium	280-287	CD59 molecule (CD59 blood group)	Homo sapiens	57-61
7691609-3	1993	In this study we observed that the surface expression of CD59 on the cultured EA.hy 926 endothelial cell line can be up-regulated to an approximately threefold higher level after a 72-h stimulation by the protein kinase C inducers phorbol-12-myristate-13 acetate (PMA; 10 nM) and calcium ionophore, A23187 (100 nM).	Calcimycin	299-305	CD59 molecule (CD59 blood group)	Homo sapiens	57-61
7691609-4	1993	Similarly, an increase in the level of CD59 expression was seen by the protein kinase A inducer dibutyryl-cyclic adenosine monophosphate.	Bucladesine	96-136	CD59 molecule (CD59 blood group)	Homo sapiens	39-43
8262081-4	1993	Seven CHF patients received a continuous intravenous infusion of dobutamine (5 micrograms.kg-1 x min-1) for 96 h. Blood samples were obtained before and every 24 h after starting the therapy.	Dobutamine	65-75	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
8262085-8	1993	Myocardial oxygen consumption following beta-blockade decreased both during spontaneous rhythm (25 +/- 15 to 16 +/- 8.8 ml min-1; P = 0.006), and during atrial pacing stress (30 +/- 13 to 23 +/- 11 ml.min-1; P = 0.004).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8262085-8	1993	Myocardial oxygen consumption following beta-blockade decreased both during spontaneous rhythm (25 +/- 15 to 16 +/- 8.8 ml min-1; P = 0.006), and during atrial pacing stress (30 +/- 13 to 23 +/- 11 ml.min-1; P = 0.004).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	201-206
8276756-0	1993	Determination of carboxyl-terminal residue and disulfide bonds of MACIF (CD59), a glycosyl-phosphatidylinositol-anchored membrane protein.	Disulfides	47-56	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
8276756-0	1993	Determination of carboxyl-terminal residue and disulfide bonds of MACIF (CD59), a glycosyl-phosphatidylinositol-anchored membrane protein.	Disulfides	47-56	CD59 molecule (CD59 blood group)	Homo sapiens	73-77
8276756-0	1993	Determination of carboxyl-terminal residue and disulfide bonds of MACIF (CD59), a glycosyl-phosphatidylinositol-anchored membrane protein.	Glycosylphosphatidylinositols	82-111	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
8276756-0	1993	Determination of carboxyl-terminal residue and disulfide bonds of MACIF (CD59), a glycosyl-phosphatidylinositol-anchored membrane protein.	Glycosylphosphatidylinositols	82-111	CD59 molecule (CD59 blood group)	Homo sapiens	73-77
8276756-1	1993	MACIF (CD59) is a glycosyl-phosphatidylinositol (GPI)-anchored membrane glycoprotein which inhibits the formation of membrane attack complex of human complement.	Glycosylphosphatidylinositols	18-47	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
8276756-1	1993	MACIF (CD59) is a glycosyl-phosphatidylinositol (GPI)-anchored membrane glycoprotein which inhibits the formation of membrane attack complex of human complement.	Glycosylphosphatidylinositols	18-47	CD59 molecule (CD59 blood group)	Homo sapiens	7-11
8276756-1	1993	MACIF (CD59) is a glycosyl-phosphatidylinositol (GPI)-anchored membrane glycoprotein which inhibits the formation of membrane attack complex of human complement.	Glycosylphosphatidylinositols	49-52	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
8276756-1	1993	MACIF (CD59) is a glycosyl-phosphatidylinositol (GPI)-anchored membrane glycoprotein which inhibits the formation of membrane attack complex of human complement.	Glycosylphosphatidylinositols	49-52	CD59 molecule (CD59 blood group)	Homo sapiens	7-11
8276756-8	1993	The pattern of disulfide bonds of MACIF was also determined with the membrane form as well as the soluble form.	Disulfides	15-24	CD59 molecule (CD59 blood group)	Homo sapiens	34-39
8282644-8	1993	We show that these gas and blood gas N2O relationships give direct derivation of cardiorespiratory parameters such as VA, Qp, the dead space-to-total ventilation ratio (VD/VT), and the shunt-to-total blood flow ratio (Qs/QT) without altering the subject"s oxygenation and that they are essentially free from recirculation effects at high forcing frequencies &gt; or = 2 min-1.	Nitrous Oxide	37-40	CD59 molecule (CD59 blood group)	Homo sapiens	370-375
8289749-3	1993	Halothane did so most profoundly, resulting in a maximum slowing of 40 beats-1 compared with a maximum slowing of about 20 beats min-1 with both isoflurane and enflurane.	Halothane	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
8289749-3	1993	Halothane did so most profoundly, resulting in a maximum slowing of 40 beats-1 compared with a maximum slowing of about 20 beats min-1 with both isoflurane and enflurane.	Isoflurane	145-155	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
8289749-3	1993	Halothane did so most profoundly, resulting in a maximum slowing of 40 beats-1 compared with a maximum slowing of about 20 beats min-1 with both isoflurane and enflurane.	Enflurane	160-169	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
7690802-10	1993	When MIRL II was analyzed by SDS-PAGE and silver staining, two prominent bands representing proteins with M(r) of 77 and 39 kDa were observed under both reducing and nonreducing conditions.	Sodium Dodecyl Sulfate	29-32	CD59 molecule (CD59 blood group)	Homo sapiens	5-9
7690802-10	1993	When MIRL II was analyzed by SDS-PAGE and silver staining, two prominent bands representing proteins with M(r) of 77 and 39 kDa were observed under both reducing and nonreducing conditions.	Silver	42-48	CD59 molecule (CD59 blood group)	Homo sapiens	5-9
8395510-5	1993	Half-logarithmic plots were linear with rate constants of 0.0058, 0.011, 0.015, and 0.020 min-1 when 3, 10, 30, and 50 microM (+)-cis-diltiazem was added, respectively.	Diltiazem	126-143	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
8214043-8	1993	Elevated plasma NEFA levels were associated with a comparable decrease in forearm phenylalanine uptake (11 +/- 2 vs. 17 +/- 2 nmol x 100 ml forearm-1 x min-1; lipid vs. control, P &lt; 0.05) and release (20 +/- 2 vs. 26 +/- 3 nmol x 100 ml forearm-1 x min-1; lipid vs. control, P &lt; 0.05).	Fatty Acids, Nonesterified	16-20	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
8214044-3	1993	Addition of angiotensin II increased whole body glucose uptake by 15% (9.2 +/- 0.5 vs. 10.8 +/- 0.8 mg.kg-1 x min-1; P = 0.011), and glucose oxidation (determined by indirect calorimetry) by 25% (4.0 +/- 0.3 vs. 4.9 +/- 0.4 mg.kg-1 x min-1; P &lt; 0.05) over insulin alone.	Glucose	48-55	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
8214058-2	1993	To test this hypothesis, in paired studies in healthy volunteers, sodium lactate (25 mumol.min-1 x kg-1) or saline was infused for 1 h in the fasting state and during 2 h of euglycemic (4.75 mM) hyperinsulinemia (approximately 400 pmol/l).	Sodium Lactate	66-80	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
8363075-8	1993	RESULTS: At 1.0 MAC, mean +/- SD CBF values for the desflurane and isoflurane groups were 18 +/- 2 and 20 +/- 3 ml x 100 g-1 x min-1, respectively.	Isoflurane	67-77	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
8398494-6	1993	RESULTS: Maximal mean (SD) oxygen consumption on bicycle ergometry was 16.0 (4.5) ml min-1 kg-1.	Oxygen	27-33	CD59 molecule (CD59 blood group)	Homo sapiens	85-95
8398519-3	1993	dose of metoclopramide 10 mg to 21 patients on an intensive care unit who were haemodynamically stable and receiving dopamine 3 micrograms kg-1 min-1.	Metoclopramide	8-22	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
8398533-2	1993	The range of output, for one type of vaporizer and dial setting (flow: 6 litre min-1) was largest with the Fluotec 3 (0.85-1.55% when dial set to 1%) and smallest with the Isotec 3 (0.85-1.15% when dial set to 1%).	fluotec	107-114	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
8398533-4	1993	Using a flow of oxygen 6 litre min-1 17% of Fluotec 3.8% of Isotec 3 and 71% of Enfluratec 3 vaporizers had outputs outside those limits.	Oxygen	16-22	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
8403176-5	1993	After surgery, end-tidal sevoflurane concentration was reduced gradually at the rate of less than 0.01%.min-1.	Sevoflurane	25-36	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
8375126-2	1993	Data analyzed from subjects with various degrees of renal dysfunction who were given single oral doses of loracarbef indicated a linear relationship between creatinine clearance (CLCR) and plasma clearance [CLP (L/hr) = 0.106.CLCR (ml/min/1.73 m2)].	loracarbef	106-116	CD59 molecule (CD59 blood group)	Homo sapiens	235-240
8403799-11	1993	In patients with alcoholic liver disease, N-ethylmaleimide-insensitive phosphatidate phosphohydrolase activity was higher in cirrhotic biopsies (5.82 +/- 0.3 nmol of Pi min-1 mg-1 of protein, n = 19) than in non-cirrhotic biopsies (2.17 +/- 0.2, n = 23) or in wedge biopsies from healthy subjects undergoing routine cholecystectomy (2.16 +/- 0.5, n = 6).	Ethylmaleimide	42-58	CD59 molecule (CD59 blood group)	Homo sapiens	169-179
8223740-5	1993	Compared to placebo, prazosin caused a significant increase in urinary sodium excretion (from 56 +/- 7 to 92 +/- 7 mumol.min-1, P &lt; 0.01), paralleled by significant increases in fractional excretion of sodium and lithium.	Prazosin	21-29	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
8223740-5	1993	Compared to placebo, prazosin caused a significant increase in urinary sodium excretion (from 56 +/- 7 to 92 +/- 7 mumol.min-1, P &lt; 0.01), paralleled by significant increases in fractional excretion of sodium and lithium.	Sodium	71-77	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
8243522-6	1993	In the saline experiment, the integrated cholecystokinin response during the first hour of bombesin-infusion (262 +/- 63 pmol 60 min-1) was significantly (P &lt; 0.01) higher than during the second (88 +/- 26 pmol 60 min-1) and third (87 +/- 31 pmol 60 min-1) hour of bombesin-infusion.	Sodium Chloride	7-13	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
8243522-6	1993	In the saline experiment, the integrated cholecystokinin response during the first hour of bombesin-infusion (262 +/- 63 pmol 60 min-1) was significantly (P &lt; 0.01) higher than during the second (88 +/- 26 pmol 60 min-1) and third (87 +/- 31 pmol 60 min-1) hour of bombesin-infusion.	Sodium Chloride	7-13	CD59 molecule (CD59 blood group)	Homo sapiens	217-222
8243522-6	1993	In the saline experiment, the integrated cholecystokinin response during the first hour of bombesin-infusion (262 +/- 63 pmol 60 min-1) was significantly (P &lt; 0.01) higher than during the second (88 +/- 26 pmol 60 min-1) and third (87 +/- 31 pmol 60 min-1) hour of bombesin-infusion.	Sodium Chloride	7-13	CD59 molecule (CD59 blood group)	Homo sapiens	217-222
8243522-7	1993	Loxiglumide augmented bombesin-stimulated cholecystokinin secretion from 262 +/- 63 pmol 60 min-1 to 453 +/- 63 pmol 60 min-1 in the first hour of bombesin infusion (P &lt; 0.01).	loxiglumide	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
8243522-7	1993	Loxiglumide augmented bombesin-stimulated cholecystokinin secretion from 262 +/- 63 pmol 60 min-1 to 453 +/- 63 pmol 60 min-1 in the first hour of bombesin infusion (P &lt; 0.01).	loxiglumide	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
8243522-8	1993	Integrated cholecystokinin values in the second (489 +/- 90 pmol 60 min-1) and third (450 +/- 74 pmol 60 min-1) hour of the loxiglumide experiment, were significantly (P &lt; 0.01) higher than in the saline experiment.	loxiglumide	124-135	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
8262701-5	1993	However, at similar lactate levels, heart rate during rowing on the water was approximately 10 beats.min-1 higher than during the ergometer multistage step test, due to the different duration of exercise.	Lactic Acid	20-27	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
8262701-5	1993	However, at similar lactate levels, heart rate during rowing on the water was approximately 10 beats.min-1 higher than during the ergometer multistage step test, due to the different duration of exercise.	Water	68-73	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
8412779-5	1993	Fasting hepatic glucose production (HGP) was also significantly decreased following metformin therapy (1.98 +/- 0.13 v 2.41 +/- 0.20 mg.kg-1 x min-1, P &lt; .02), whereas fasting insulin and C-peptide concentrations remained unaltered.	Metformin	84-93	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
8412779-7	1993	Insulin-stimulated glucose uptake was assessed using the hyperinsulinemic euglycemic clamp technique and was increased post-metformin (3.8 +/- 0.6 v 3.1 +/- 0.7 mg.kg-1 x min-1, P &lt; .05).	Glucose	19-26	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
7511834-3	1993	One peptide obtained by cyanogen bromide cleavage has significant (approximately 60%) homology with CD59 protein (protectin).	Cyanogen Bromide	24-40	CD59 molecule (CD59 blood group)	Homo sapiens	100-104
8112140-2	1993	In group 1, 10 cases were treated with PGE1 at a dosage of 20ng/kg.min-1, It was found that pulmonary arterial pressure (mPAP) and pulmonary vascular resistance (PVR) decreased by 23.3% and 38.7% respectively, CI and DO2 increased significantly; blood viscosity decreased significantly, but mean arterial pressure (MAP) and PaO2 were not affected.	Alprostadil	39-43	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
8112140-4	1993	In group 2, 8 of the 10 cases were treated with PGE1 at a dosage of 40ng/kg.min-1.	Alprostadil	48-52	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
8112140-7	1993	These results showed that PGE1 at a dosage of 20ng/kg.min-1 is effective, well-tolerated and yields less side effects.	Alprostadil	26-30	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
8347600-4	1993	The first step, guanosine-dependent cleavage of the phosphodiester bond at the 5" splice site, occurs with kcat congruent to 14 min-1 and kcat/Km = 5 x 10(4) M-1 min-1 (32 degrees C, 15 mM MgCl2), unexpectedly efficient for a small group I intron.	Guanosine	16-25	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
8347600-4	1993	The first step, guanosine-dependent cleavage of the phosphodiester bond at the 5" splice site, occurs with kcat congruent to 14 min-1 and kcat/Km = 5 x 10(4) M-1 min-1 (32 degrees C, 15 mM MgCl2), unexpectedly efficient for a small group I intron.	Guanosine	16-25	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
8347600-4	1993	The first step, guanosine-dependent cleavage of the phosphodiester bond at the 5" splice site, occurs with kcat congruent to 14 min-1 and kcat/Km = 5 x 10(4) M-1 min-1 (32 degrees C, 15 mM MgCl2), unexpectedly efficient for a small group I intron.	Magnesium Chloride	189-194	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
8346593-5	1993	In the enalapril group, the median decline in GFR was -0.20 (range, +0.18 to -7.11) mL/min/1.73 m2/month, and in the control group, it was -0.31 (+0.01 to -1.97) mL/min/1.73 m2/month (p &lt; 0.05).	Enalapril	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
8346593-5	1993	In the enalapril group, the median decline in GFR was -0.20 (range, +0.18 to -7.11) mL/min/1.73 m2/month, and in the control group, it was -0.31 (+0.01 to -1.97) mL/min/1.73 m2/month (p &lt; 0.05).	Enalapril	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
8368288-6	1993	Ethanol decreased the antilipolytic action of insulin by approximately 40% [with insulin alone, glycerol rate of appearance (Ra) decreased from 1.8 to 0.6 mumol.kg-1 x min-1; with insulin + ethanol, it only decreased from 1.8 to 1.1 mumol.kg-1 x min-1].	Ethanol	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
8368288-6	1993	Ethanol decreased the antilipolytic action of insulin by approximately 40% [with insulin alone, glycerol rate of appearance (Ra) decreased from 1.8 to 0.6 mumol.kg-1 x min-1; with insulin + ethanol, it only decreased from 1.8 to 1.1 mumol.kg-1 x min-1].	Ethanol	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	246-251
8368288-6	1993	Ethanol decreased the antilipolytic action of insulin by approximately 40% [with insulin alone, glycerol rate of appearance (Ra) decreased from 1.8 to 0.6 mumol.kg-1 x min-1; with insulin + ethanol, it only decreased from 1.8 to 1.1 mumol.kg-1 x min-1].	Glycerol	96-104	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
8368288-8	1993	Fatty acid reesterification was not affected by insulin but tripled (from 0.6 to 1.9 mumol.kg-1 x min-1) in response to insulin plus ethanol.	Fatty Acids	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
8368288-8	1993	Fatty acid reesterification was not affected by insulin but tripled (from 0.6 to 1.9 mumol.kg-1 x min-1) in response to insulin plus ethanol.	Ethanol	133-140	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
7687899-1	1993	The membrane inhibitor of reactive lysis (MIRL) is an 18-Kd glycosyl phosphatidylinositol anchored membrane glycoprotein that inhibits the cytolytic activity of complement.	Glycosylphosphatidylinositols	60-89	CD59 molecule (CD59 blood group)	Homo sapiens	4-40
7687899-1	1993	The membrane inhibitor of reactive lysis (MIRL) is an 18-Kd glycosyl phosphatidylinositol anchored membrane glycoprotein that inhibits the cytolytic activity of complement.	Glycosylphosphatidylinositols	60-89	CD59 molecule (CD59 blood group)	Homo sapiens	42-46
7687899-7	1993	However, incubation with phorbol 12-myristate 13 acetate (PMA), induced a marked increase in MIRL RNA as determined by Northern blot analysis.	Tetradecanoylphorbol Acetate	25-56	CD59 molecule (CD59 blood group)	Homo sapiens	93-97
7687899-7	1993	However, incubation with phorbol 12-myristate 13 acetate (PMA), induced a marked increase in MIRL RNA as determined by Northern blot analysis.	Tetradecanoylphorbol Acetate	58-61	CD59 molecule (CD59 blood group)	Homo sapiens	93-97
8076058-9	1993	catecholamine dosage was significantly less in the leucocyte-depleted group than in controls (1.1(1.9) versus 4.9(2.2) micrograms kg-1 min-1; P &lt; 0.05), whereas the cardiac index was significantly higher (3.3(0.5) versus 2.3(0.4) l min-1 m-2; P &lt; 0.05).	Catecholamines	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
8076058-9	1993	catecholamine dosage was significantly less in the leucocyte-depleted group than in controls (1.1(1.9) versus 4.9(2.2) micrograms kg-1 min-1; P &lt; 0.05), whereas the cardiac index was significantly higher (3.3(0.5) versus 2.3(0.4) l min-1 m-2; P &lt; 0.05).	Catecholamines	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	235-240
8403783-11	1993	In contrast, the effect of angiotensin II on sodium excretion showed a flat dose-response curve beyond 5 ng min-1 kg-1.	Sodium	45-51	CD59 molecule (CD59 blood group)	Homo sapiens	108-118
8403788-9	1993	Hepatic glucose production was lower (1.5 +/- 0.4 versus 2.3 +/- 0.3 mg min-1 kg-1, P &lt; 0.05) and peripheral glucose uptake was higher (7.4 +/- 1.0 versus 5.6 +/- 0.6 mg min-1 kg-1, P &lt; 0.01) during infusion of the hormones compared with during hypoglycaemia.	Glucose	8-15	CD59 molecule (CD59 blood group)	Homo sapiens	72-82
8404943-13	1993	Taprostene was well tolerated up to 25 ng.kg-1 x min-1.	taprostene	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7691143-6	1993	Following irradiation (60Co, 1.0 Gy/min-1 over 10(min), PG binding sites (PGE1: Bmax = 266 +/- 153 fmol mg-1 protein, Kd = 5.0 +/- 5.0 nM; PGE2: Bmax = 148 +/- 66 fmol mg-1 protein, Kd = 4.7 +/- 3.6 nM; PGI2: Bmax = 325 +/- 194 fmol mg-1 protein, Kd = 6.8 +/- 7.1 nM) were significantly (P &lt; 0.01) diminished.	Prostaglandins	56-58	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
8404995-3	1993	With the highest lactate infusions, plasma lactate increased up to 7 mM (compared to 1.1 +/- 0.13 mM during control sodium bicarbonate infusions, n = 10) and LGN averaged 4.73 +/- 0.23 mumol kg-1 min-1 (compared to 1.57 +/- 0.26 mumol kg-1 min-1 in bicarbonate control experiments, P &lt; 0.001).	Lactic Acid	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	196-201
8404995-4	1993	The data relating plasma lactate concentration to LGN best fit a sigmoidal curve which plateaued at plasma lactate concentrations of approximately 6 mM and yielded an ED50 of 2.04 +/- 0.20 (SD) mM and a Vmax (6.25 +/- 1.2) (SD) (mumol kg-1 min-1).	Lactic Acid	25-32	CD59 molecule (CD59 blood group)	Homo sapiens	240-245
8404995-3	1993	With the highest lactate infusions, plasma lactate increased up to 7 mM (compared to 1.1 +/- 0.13 mM during control sodium bicarbonate infusions, n = 10) and LGN averaged 4.73 +/- 0.23 mumol kg-1 min-1 (compared to 1.57 +/- 0.26 mumol kg-1 min-1 in bicarbonate control experiments, P &lt; 0.001).	Lactic Acid	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	240-245
8371659-4	1993	Results indicated the standard error of estimate for the predicted oxygen consumption values ranged from 80-156 ml.min-1, with correlations between the actual and predicted values ranging from r = 0.35 to r = 0.67.	Oxygen	67-73	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
8415813-2	1993	Haemodynamic and renal functional response to low dose PGE1 (0.02 microgram kg-1 min-1) (group A) or saline (group B) infusion via peripheral vein during CPB was evaluated in 20 patients who underwent cardiac surgery.	Alprostadil	55-59	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
8370236-11	1993	The K+/Na+ excretion ratio increased from a basal value of 10 +/- 1 to 42 +/- 11 (P &lt; 0.01) at the highest dose of adenosine, and renal oxygen consumption decreased from 17 +/- 2 to 9 +/- 1 ml min-1 (P &lt; 0.001).	Adenosine	118-127	CD59 molecule (CD59 blood group)	Homo sapiens	196-201
8403135-7	1993	Anaesthesia was induced with a ketamine infusion of 1 mg.kg-1 x min-1 until loss of consciousness.	Ketamine	31-39	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
8396523-7	1993	The glucose-induced thermogenesis in the 180 min following the glucose load was 93.6 +/- 9.9 kJ 180 min-1 before chemotherapy.	Glucose	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
7693582-0	1993	HRF20/CD59 complement regulatory protein expression is phenotype-dependent and inducible by the hypomethylating agent 5-azacytidine on Burkitt"s lymphoma cell lines.	Azacitidine	118-131	CD59 molecule (CD59 blood group)	Homo sapiens	6-10
8396523-7	1993	The glucose-induced thermogenesis in the 180 min following the glucose load was 93.6 +/- 9.9 kJ 180 min-1 before chemotherapy.	Glucose	63-70	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
8396523-9	1993	The glucose-induced thermogenesis was significantly reduced to 47.7 +/- 10.2 kJ 180 min-1 (P &lt; 0.05) after chemotherapy.	Glucose	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
8396523-10	1993	The oxygen uptake in resting skeletal muscles was 6.9 +/- 0.3 mumol 100 g-1 min-1 before chemotherapy and 7.0 +/- 0.7 mumol 100 g-1 min-1 after chemotherapy.	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
8396523-10	1993	The oxygen uptake in resting skeletal muscles was 6.9 +/- 0.3 mumol 100 g-1 min-1 before chemotherapy and 7.0 +/- 0.7 mumol 100 g-1 min-1 after chemotherapy.	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
7693582-0	1993	HRF20/CD59 complement regulatory protein expression is phenotype-dependent and inducible by the hypomethylating agent 5-azacytidine on Burkitt"s lymphoma cell lines.	Azacitidine	118-131	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
7693582-5	1993	Expression of CD59 was upregulated by 5-azacytidine, a drug inhibiting cytosine methylation, on CD59-negative cell lines.	Azacitidine	38-51	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
7693582-5	1993	Expression of CD59 was upregulated by 5-azacytidine, a drug inhibiting cytosine methylation, on CD59-negative cell lines.	Azacitidine	38-51	CD59 molecule (CD59 blood group)	Homo sapiens	96-100
7693582-5	1993	Expression of CD59 was upregulated by 5-azacytidine, a drug inhibiting cytosine methylation, on CD59-negative cell lines.	Cytosine	71-79	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
8350486-5	1993	Nine of 40 patients (23%) with cervical epidural anesthesia showed heart rate increases of less than 3 beats.min-1 following atropine 0.01 mg.kg-1.	Atropine	125-133	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
8376256-4	1993	Glycerol Ra and free fatty acid Ra in the athletes (7.33 +/- 0.68 and 14.88 +/- 1.35 mumol.kg-1 x min-1, respectively) were two- to threefold higher than the values in untrained control subjects (2.53 +/- 0.15 and 7.64 +/- 0.92 mumol.kg-1 x min-1, respectively; P &lt; 0.02).	Glycerol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
8376256-4	1993	Glycerol Ra and free fatty acid Ra in the athletes (7.33 +/- 0.68 and 14.88 +/- 1.35 mumol.kg-1 x min-1, respectively) were two- to threefold higher than the values in untrained control subjects (2.53 +/- 0.15 and 7.64 +/- 0.92 mumol.kg-1 x min-1, respectively; P &lt; 0.02).	Glycerol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	241-246
8376256-4	1993	Glycerol Ra and free fatty acid Ra in the athletes (7.33 +/- 0.68 and 14.88 +/- 1.35 mumol.kg-1 x min-1, respectively) were two- to threefold higher than the values in untrained control subjects (2.53 +/- 0.15 and 7.64 +/- 0.92 mumol.kg-1 x min-1, respectively; P &lt; 0.02).	Radium	9-11	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
8376256-4	1993	Glycerol Ra and free fatty acid Ra in the athletes (7.33 +/- 0.68 and 14.88 +/- 1.35 mumol.kg-1 x min-1, respectively) were two- to threefold higher than the values in untrained control subjects (2.53 +/- 0.15 and 7.64 +/- 0.92 mumol.kg-1 x min-1, respectively; P &lt; 0.02).	Fatty Acids, Nonesterified	16-31	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
8376256-4	1993	Glycerol Ra and free fatty acid Ra in the athletes (7.33 +/- 0.68 and 14.88 +/- 1.35 mumol.kg-1 x min-1, respectively) were two- to threefold higher than the values in untrained control subjects (2.53 +/- 0.15 and 7.64 +/- 0.92 mumol.kg-1 x min-1, respectively; P &lt; 0.02).	Radium	32-34	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
8376256-5	1993	The total rate of triglyceride-fatty acid cycling was approximately four-fold higher in the athletes (16.86 +/- 2.07 mumol.kg-1 x min-1) than in the control subjects (3.91 +/- 0.36 mumol.kg-1 x min-1).	triglyceride-fatty acid	18-41	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
8376256-5	1993	The total rate of triglyceride-fatty acid cycling was approximately four-fold higher in the athletes (16.86 +/- 2.07 mumol.kg-1 x min-1) than in the control subjects (3.91 +/- 0.36 mumol.kg-1 x min-1).	triglyceride-fatty acid	18-41	CD59 molecule (CD59 blood group)	Homo sapiens	194-199
8350486-6	1993	And 30 of 40 patients (75%) required supplementary atropine 0.01 mg.kg-1 to increase heart rate for more than 20 beats.min-1 from baseline values.	Atropine	51-59	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
8505335-6	1993	The first-order dissociation rate constant in the presence of 35 mM SDS at 22 degrees C had a koff value of 1.4 x 10(-2) min-1, which corresponds to a half-life of 49.5 min.	Sodium Dodecyl Sulfate	68-71	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
8319693-4	1993	The purified enzyme metabolized arachidonic acid almost exclusively to 12-hydroperoxyeicosatetraenoic acid with little, if any, epoxyalcohol or reduction products and had a Vmax of 2-4 mumol min-1 mg protein-1, Km of 10 microM and kcat of approximately 250 min-1.	Arachidonic Acid	32-48	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
8319693-4	1993	The purified enzyme metabolized arachidonic acid almost exclusively to 12-hydroperoxyeicosatetraenoic acid with little, if any, epoxyalcohol or reduction products and had a Vmax of 2-4 mumol min-1 mg protein-1, Km of 10 microM and kcat of approximately 250 min-1.	Arachidonic Acid	32-48	CD59 molecule (CD59 blood group)	Homo sapiens	257-262
8319693-4	1993	The purified enzyme metabolized arachidonic acid almost exclusively to 12-hydroperoxyeicosatetraenoic acid with little, if any, epoxyalcohol or reduction products and had a Vmax of 2-4 mumol min-1 mg protein-1, Km of 10 microM and kcat of approximately 250 min-1.	12-HPETE	71-106	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
8319693-4	1993	The purified enzyme metabolized arachidonic acid almost exclusively to 12-hydroperoxyeicosatetraenoic acid with little, if any, epoxyalcohol or reduction products and had a Vmax of 2-4 mumol min-1 mg protein-1, Km of 10 microM and kcat of approximately 250 min-1.	12-HPETE	71-106	CD59 molecule (CD59 blood group)	Homo sapiens	257-262
8319693-4	1993	The purified enzyme metabolized arachidonic acid almost exclusively to 12-hydroperoxyeicosatetraenoic acid with little, if any, epoxyalcohol or reduction products and had a Vmax of 2-4 mumol min-1 mg protein-1, Km of 10 microM and kcat of approximately 250 min-1.	epoxyalcohol	128-140	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
8319693-4	1993	The purified enzyme metabolized arachidonic acid almost exclusively to 12-hydroperoxyeicosatetraenoic acid with little, if any, epoxyalcohol or reduction products and had a Vmax of 2-4 mumol min-1 mg protein-1, Km of 10 microM and kcat of approximately 250 min-1.	epoxyalcohol	128-140	CD59 molecule (CD59 blood group)	Homo sapiens	257-262
8333527-8	1993	The initial rate of TC influx followed saturation kinetics with an apparent Michaelis constant of 112 +/- 23 microM and maximal velocity of 2.01 +/- 0.19 nmol.mg protein-1.min-1.	Taurocholic Acid	20-22	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
8498380-3	1993	In 11 subjects, oxidative metabolism was also estimated at rest and peak dobutamine infusion using the clearance rate of C-11 acetate, k mono (min-1).	carbon-11 acetate	121-133	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
8329290-7	1993	Dilevalol decreased resting heart rate compared with nifedipine (73 vs 92 beats min-1 respectively, P &lt; 0.01).	Labetalol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
8329290-8	1993	Dilevalol limited the exercise induced rise in heart rate more than nifedipine (36 vs 48 beats min-1 respectively, P &lt; 0.01).	Labetalol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
8329290-11	1993	After exercise, dilevalol caused an increase in excess blood flow compared with placebo (10.8 vs 5.1 ml min-1 dl-1 respectively, P &lt; 0.01).	Labetalol	16-25	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
8334827-3	1993	In microalbuminuric patients the rise in albumin excretion rate after exercise on indomethacin (7 micrograms min-1) was lower than after placebo (29 micrograms min-1, p &lt; 0.001) whereas the rise in albumin excretion rate with metoprolol during exercise (18 micrograms min-1) did not differ from placebo (p = 0.48), in spite of the expected less marked increase in blood pressure.	Indomethacin	82-94	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
8334827-3	1993	In microalbuminuric patients the rise in albumin excretion rate after exercise on indomethacin (7 micrograms min-1) was lower than after placebo (29 micrograms min-1, p &lt; 0.001) whereas the rise in albumin excretion rate with metoprolol during exercise (18 micrograms min-1) did not differ from placebo (p = 0.48), in spite of the expected less marked increase in blood pressure.	Indomethacin	82-94	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
8334827-3	1993	In microalbuminuric patients the rise in albumin excretion rate after exercise on indomethacin (7 micrograms min-1) was lower than after placebo (29 micrograms min-1, p &lt; 0.001) whereas the rise in albumin excretion rate with metoprolol during exercise (18 micrograms min-1) did not differ from placebo (p = 0.48), in spite of the expected less marked increase in blood pressure.	Indomethacin	82-94	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
8334829-5	1993	Glycerol production measured isotopically decreased with insulin (-0.54 (-1.50-0.63) mumol kg-1 min-1) and with the low affinity analogue (-0.74 (-1.76-0.72) mumol kg-1 min-1), but the high affinity analogue at these doses had no significant effect on glycerol turnover (-0.19 (-0.74-1.13) mumol kg-1 min-1).	Glycerol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
8334829-5	1993	Glycerol production measured isotopically decreased with insulin (-0.54 (-1.50-0.63) mumol kg-1 min-1) and with the low affinity analogue (-0.74 (-1.76-0.72) mumol kg-1 min-1), but the high affinity analogue at these doses had no significant effect on glycerol turnover (-0.19 (-0.74-1.13) mumol kg-1 min-1).	Glycerol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
8334829-5	1993	Glycerol production measured isotopically decreased with insulin (-0.54 (-1.50-0.63) mumol kg-1 min-1) and with the low affinity analogue (-0.74 (-1.76-0.72) mumol kg-1 min-1), but the high affinity analogue at these doses had no significant effect on glycerol turnover (-0.19 (-0.74-1.13) mumol kg-1 min-1).	Glycerol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
8339708-5	1993	For the total ATPase activity of digitonin-treated cells, mainly representing the dynein ATPase, a maximal activity of 20.3 nmol ATP x min-1 x microliters cells-1 (mean +/- S.D.	Digitonin	33-42	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
8339708-5	1993	For the total ATPase activity of digitonin-treated cells, mainly representing the dynein ATPase, a maximal activity of 20.3 nmol ATP x min-1 x microliters cells-1 (mean +/- S.D.	Adenosine Triphosphate	14-17	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
7688416-5	1993	Decay accelerating factor</protein-id> (DAF, CD55) and the membrane attack complex (MAC) inhibitor (CD59) are two cell proteins whose sole function is to protect cells from the action of complement, the former affecting the earlier components of the complement cascade, and the latter the terminal ones; both are bound to the cell surface via a glycosylphosphatidylinositol link.	Glycosylphosphatidylinositols	345-373	CD59 molecule (CD59 blood group)	Homo sapiens	100-104
8229846-5	1993	The slopes of the relationship between minute ventilation (VI) and the increase of end tidal PCO2 (delta P(ET), CO2) were 3.27 +/- 0.23 and 2.76 +/- 0.24 1 min-1 mmHg-1 supine and upright, respectively.	pco2	93-97	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
8378116-4	1993	In 13 of 16 patients, the glucose production rate exceeded 1.0 mg.kg-1 x min-1.	Glucose	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
8378116-5	1993	Infants born from mothers who had been receiving steroids antenatally had higher glucose production rates (2.3 +/- 1.1 mg.kg-1 x min-1) compared with infants from mothers who had not (1.1 +/- 0.8 mg.kg-1 x min-1, p = 0.036).	Steroids	49-57	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
8378116-5	1993	Infants born from mothers who had been receiving steroids antenatally had higher glucose production rates (2.3 +/- 1.1 mg.kg-1 x min-1) compared with infants from mothers who had not (1.1 +/- 0.8 mg.kg-1 x min-1, p = 0.036).	Steroids	49-57	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
8378116-5	1993	Infants born from mothers who had been receiving steroids antenatally had higher glucose production rates (2.3 +/- 1.1 mg.kg-1 x min-1) compared with infants from mothers who had not (1.1 +/- 0.8 mg.kg-1 x min-1, p = 0.036).	Glucose	81-88	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
8378116-6	1993	The glucose oxidized (2.9 +/- 1.0 mg.kg-1 x min-1) was lower than the amount of glucose infused (p = 0.005) and was not different for appropriate-for-gestational-age and small-for-gestational-age infants.	Glucose	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
8378116-9	1993	We conclude that preterm infants on the first day of life receiving a glucose infusion of 4.2 mg.kg-1 x min-1 continue to produce glucose.	Glucose	70-77	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
8378116-9	1993	We conclude that preterm infants on the first day of life receiving a glucose infusion of 4.2 mg.kg-1 x min-1 continue to produce glucose.	Glucose	130-137	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
8496171-1	1993	The single histidine residue (His-15) in hen egg white lysozyme (EC 3.2.1.17) was chemically modified by diethyl pyrocarbonate (DEPC) to form exclusively the mono-N-carbethoxyimidazole adduct (second order rate constant of 252 +/- 16 M-1 min-1).	Histidine	11-20	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
8496171-1	1993	The single histidine residue (His-15) in hen egg white lysozyme (EC 3.2.1.17) was chemically modified by diethyl pyrocarbonate (DEPC) to form exclusively the mono-N-carbethoxyimidazole adduct (second order rate constant of 252 +/- 16 M-1 min-1).	Histidine	30-33	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
8496171-1	1993	The single histidine residue (His-15) in hen egg white lysozyme (EC 3.2.1.17) was chemically modified by diethyl pyrocarbonate (DEPC) to form exclusively the mono-N-carbethoxyimidazole adduct (second order rate constant of 252 +/- 16 M-1 min-1).	Diethyl Pyrocarbonate	105-126	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
8496171-1	1993	The single histidine residue (His-15) in hen egg white lysozyme (EC 3.2.1.17) was chemically modified by diethyl pyrocarbonate (DEPC) to form exclusively the mono-N-carbethoxyimidazole adduct (second order rate constant of 252 +/- 16 M-1 min-1).	Diethyl Pyrocarbonate	128-132	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
8496171-1	1993	The single histidine residue (His-15) in hen egg white lysozyme (EC 3.2.1.17) was chemically modified by diethyl pyrocarbonate (DEPC) to form exclusively the mono-N-carbethoxyimidazole adduct (second order rate constant of 252 +/- 16 M-1 min-1).	mono-n-carbethoxyimidazole	158-184	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
8480681-2	1993	In control subjects (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E reduced the area under the curve for glucose (344 +/- 21 vs 287 +/- 13 mmol.L-1 x min-1; P &lt; 0.05) and increased total body glucose disposal (39.0 +/- 0.3 vs 47.6 +/- 0.4 mumol.kg lean body mass-1 x min-1; P &lt; 0.05) and non-oxidative glucose metabolism (23.4 +/- 0.2 vs 30.8 +/- 0.3 mumol.kg lean body mass-1 x min-1; P &lt; 0.05).	Vitamin E	87-96	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
8480681-2	1993	In control subjects (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E reduced the area under the curve for glucose (344 +/- 21 vs 287 +/- 13 mmol.L-1 x min-1; P &lt; 0.05) and increased total body glucose disposal (39.0 +/- 0.3 vs 47.6 +/- 0.4 mumol.kg lean body mass-1 x min-1; P &lt; 0.05) and non-oxidative glucose metabolism (23.4 +/- 0.2 vs 30.8 +/- 0.3 mumol.kg lean body mass-1 x min-1; P &lt; 0.05).	Vitamin E	87-96	CD59 molecule (CD59 blood group)	Homo sapiens	299-304
8480681-2	1993	In control subjects (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E reduced the area under the curve for glucose (344 +/- 21 vs 287 +/- 13 mmol.L-1 x min-1; P &lt; 0.05) and increased total body glucose disposal (39.0 +/- 0.3 vs 47.6 +/- 0.4 mumol.kg lean body mass-1 x min-1; P &lt; 0.05) and non-oxidative glucose metabolism (23.4 +/- 0.2 vs 30.8 +/- 0.3 mumol.kg lean body mass-1 x min-1; P &lt; 0.05).	Vitamin E	87-96	CD59 molecule (CD59 blood group)	Homo sapiens	299-304
8480681-2	1993	In control subjects (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E reduced the area under the curve for glucose (344 +/- 21 vs 287 +/- 13 mmol.L-1 x min-1; P &lt; 0.05) and increased total body glucose disposal (39.0 +/- 0.3 vs 47.6 +/- 0.4 mumol.kg lean body mass-1 x min-1; P &lt; 0.05) and non-oxidative glucose metabolism (23.4 +/- 0.2 vs 30.8 +/- 0.3 mumol.kg lean body mass-1 x min-1; P &lt; 0.05).	Glucose	134-141	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
8480681-3	1993	In diabetics (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E supplementation reduced glucose area under the curve (614 +/- 129 vs 544 +/- 98 mmol.L-1 x min-1; P &lt; 0.03) and increased glucose disappearance (19.4 +/- 0.4 vs 26.4 +/- 0.7 mumol.kg lean body mass-1.min-1; P &lt; 0.03), total glucose disposal (19.0 +/- 0.7 vs 28.1 +/- 0.4 mumol.kg lean body mass-1 x min-1; P &lt; 0.02), and nonoxidative glucose metabolism (8.5 +/- 0.3 vs 13.9 +/- 0.3 mumol.kg lean body mass-1 x min-1; P &lt; 0.02).	Vitamin E	80-89	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
8480681-3	1993	In diabetics (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E supplementation reduced glucose area under the curve (614 +/- 129 vs 544 +/- 98 mmol.L-1 x min-1; P &lt; 0.03) and increased glucose disappearance (19.4 +/- 0.4 vs 26.4 +/- 0.7 mumol.kg lean body mass-1.min-1; P &lt; 0.03), total glucose disposal (19.0 +/- 0.7 vs 28.1 +/- 0.4 mumol.kg lean body mass-1 x min-1; P &lt; 0.02), and nonoxidative glucose metabolism (8.5 +/- 0.3 vs 13.9 +/- 0.3 mumol.kg lean body mass-1 x min-1; P &lt; 0.02).	Vitamin E	80-89	CD59 molecule (CD59 blood group)	Homo sapiens	293-298
8480681-3	1993	In diabetics (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E supplementation reduced glucose area under the curve (614 +/- 129 vs 544 +/- 98 mmol.L-1 x min-1; P &lt; 0.03) and increased glucose disappearance (19.4 +/- 0.4 vs 26.4 +/- 0.7 mumol.kg lean body mass-1.min-1; P &lt; 0.03), total glucose disposal (19.0 +/- 0.7 vs 28.1 +/- 0.4 mumol.kg lean body mass-1 x min-1; P &lt; 0.02), and nonoxidative glucose metabolism (8.5 +/- 0.3 vs 13.9 +/- 0.3 mumol.kg lean body mass-1 x min-1; P &lt; 0.02).	Vitamin E	80-89	CD59 molecule (CD59 blood group)	Homo sapiens	293-298
8480681-3	1993	In diabetics (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E supplementation reduced glucose area under the curve (614 +/- 129 vs 544 +/- 98 mmol.L-1 x min-1; P &lt; 0.03) and increased glucose disappearance (19.4 +/- 0.4 vs 26.4 +/- 0.7 mumol.kg lean body mass-1.min-1; P &lt; 0.03), total glucose disposal (19.0 +/- 0.7 vs 28.1 +/- 0.4 mumol.kg lean body mass-1 x min-1; P &lt; 0.02), and nonoxidative glucose metabolism (8.5 +/- 0.3 vs 13.9 +/- 0.3 mumol.kg lean body mass-1 x min-1; P &lt; 0.02).	Vitamin E	80-89	CD59 molecule (CD59 blood group)	Homo sapiens	293-298
8498539-6	1993	The apparent Km for corticosterone was 16.3 x 10(-8) M, a value comparable to that observed for enzyme from CCD, and a Vmax of 4.8 x 10(-12) mol.mg protein-1.min-1.	Corticosterone	20-34	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
8317683-15	1993	The grand mean oxygen uptake rate was 2.5 ml.kg-1 x min-1 or 100 ml.min-1 x m-2.	Oxygen	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
8317683-15	1993	The grand mean oxygen uptake rate was 2.5 ml.kg-1 x min-1 or 100 ml.min-1 x m-2.	Oxygen	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
8317683-17	1993	The mean oxygen uptake rate at 10 min was between 2.0 and 2.2 ml.kg-1 x min-1 in all groups.	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
8317683-18	1993	At 30 min the mean oxygen uptake rates were 2.6 to 2.8 ml.kg-1 x min-1.	Oxygen	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
8484510-9	1993	During one propofol anesthetic, an esmolol infusion (100 micrograms.kg-1 x min-1) was started 10 min before stimulation to determine whether this agent would blunt the pupillary response.	esmolol	35-42	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
8491006-14	1993	After intravenous dipyridamole, collateral-dependent myocardial blood flow increased from 78 +/- 5 to 238 +/- 54 mL.min-1.100 g-1 in three patients with normal wall motion and from 88 +/- 17 to only 112 +/- 44 mL.min-1.100 g-1 in eight patients with regional dysfunction.	Dipyridamole	18-30	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
8491006-14	1993	After intravenous dipyridamole, collateral-dependent myocardial blood flow increased from 78 +/- 5 to 238 +/- 54 mL.min-1.100 g-1 in three patients with normal wall motion and from 88 +/- 17 to only 112 +/- 44 mL.min-1.100 g-1 in eight patients with regional dysfunction.	Dipyridamole	18-30	CD59 molecule (CD59 blood group)	Homo sapiens	213-218
8508613-3	1993	The 5 mg glucose.kg ideal body weight.min-1 continuous infusion of glucose with model assessment (CIGMA) test was used to quantitate glucose tolerance, beta cell function, and insulin sensitivity.	Glucose	67-74	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
8508864-9	1993	Dobutamine also significantly increased heart rate from a mean of 108 beats.min-1 to 117 beats.min-1 (P &lt; 0.001).	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
8508864-9	1993	Dobutamine also significantly increased heart rate from a mean of 108 beats.min-1 to 117 beats.min-1 (P &lt; 0.001).	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
8335545-1	1993	Renal function was investigated in eight normal subjects before and during infusion of dopamine (3 micrograms.kg-1 x min-1) at sea level (SL) and at high altitude (HA, 4,350 m).	Dopamine	87-95	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
7683035-2	1993	Analyses by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, Western blotting, and Edman degradation indicated that this protein, SP CD59, was similar, if not identical, to CD59 isolated from erythrocyte (E) membranes (E CD59).	Sodium Dodecyl Sulfate	12-34	CD59 molecule (CD59 blood group)	Homo sapiens	143-147
7683035-3	1993	Like purified E CD59, SP CD59 also possesses a glycosyl phosphatidyl inositol (GPI) anchor and incorporates into the membranes of heterologous cells where it inhibits lysis by the human MAC.	Glycosylphosphatidylinositols	47-77	CD59 molecule (CD59 blood group)	Homo sapiens	25-29
7683035-3	1993	Like purified E CD59, SP CD59 also possesses a glycosyl phosphatidyl inositol (GPI) anchor and incorporates into the membranes of heterologous cells where it inhibits lysis by the human MAC.	Glycosylphosphatidylinositols	79-82	CD59 molecule (CD59 blood group)	Homo sapiens	25-29
8515540-2	1993	Lidocaine was infused in 4 different doses: 2 mg.kg-1 bolus + 100 micrograms.kg-1 x min-1, 3 mg.kg-1 bolus + 200 micrograms.kg-1 x min-1, 6 mg.kg-1 bolus + 400 micrograms.kg-1 x min-1 and 12 mg.kg-1 bolus + 800 micrograms.kg-1 x min-1.	Lidocaine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
8355864-2	1993	Anesthesia was provided by fentanyl infusion reaching the final dose of 100 micrograms.kg.min-1 in 10 minutes before skin incision.	Fentanyl	27-35	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
8515540-2	1993	Lidocaine was infused in 4 different doses: 2 mg.kg-1 bolus + 100 micrograms.kg-1 x min-1, 3 mg.kg-1 bolus + 200 micrograms.kg-1 x min-1, 6 mg.kg-1 bolus + 400 micrograms.kg-1 x min-1 and 12 mg.kg-1 bolus + 800 micrograms.kg-1 x min-1.	Lidocaine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8515540-2	1993	Lidocaine was infused in 4 different doses: 2 mg.kg-1 bolus + 100 micrograms.kg-1 x min-1, 3 mg.kg-1 bolus + 200 micrograms.kg-1 x min-1, 6 mg.kg-1 bolus + 400 micrograms.kg-1 x min-1 and 12 mg.kg-1 bolus + 800 micrograms.kg-1 x min-1.	Lidocaine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8515540-2	1993	Lidocaine was infused in 4 different doses: 2 mg.kg-1 bolus + 100 micrograms.kg-1 x min-1, 3 mg.kg-1 bolus + 200 micrograms.kg-1 x min-1, 6 mg.kg-1 bolus + 400 micrograms.kg-1 x min-1 and 12 mg.kg-1 bolus + 800 micrograms.kg-1 x min-1.	Lidocaine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8513142-1	1993	In chromaffin granule ghosts, the Na+/Ca2+ exchanger in the granule membrane can provide a high affinity (Km 1-3 microM) and high capacity (Vmax 50-100 nmol mg min-2) mechanism for Ca2+ accumulation.	chromaffin	3-13	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
8481388-9	1993	Glycerol was found to be a potent stimulator of lyso PLA activity and specific activities up to 50 mumol min-1 mg-1 were observed.	Glycerol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	105-115
7681703-8	1993	In conclusion, it appears that the expression of glycosylphosphatidylinositol-linked membrane proteins by leukemic cells was heterogeneous and discordant in our patient, and that the leukemic cells were derived from the PNH clone because of their deficiency of CD59/MACIF.	Glycosylphosphatidylinositols	49-77	CD59 molecule (CD59 blood group)	Homo sapiens	266-271
8490108-9	1993	h, the total body clearance, CLtot, was 9.53 +/- 1.08 ml min-1 and the distribution volume at steady state, Vd,ss, was 7070 +/- 960 ml kg-1.	cltot	29-34	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
8499195-5	1993	The average effective therapeutic infusion of alfentanil was 0.140 (0.032) mg min-1.	Alfentanil	46-56	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
8471437-4	1993	The input corrected uptake rate of 11C-methionine (Ki) in breast cancer metastases before the treatment ranged between 0.035 and 0.186 1 min-1 and the standardised uptake value (SUV) between 2.0 and 11.4.	carbon-11 methionine	35-49	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
8471437-4	1993	The input corrected uptake rate of 11C-methionine (Ki) in breast cancer metastases before the treatment ranged between 0.035 and 0.186 1 min-1 and the standardised uptake value (SUV) between 2.0 and 11.4.	KS I	51-53	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
8491224-7	1993	Fourteen patients were able to tolerate dobutamine 20 micrograms kg-1 min-1.	Dobutamine	40-50	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
8466064-7	1993	Final infusion requirements (mean +/- SD) were 9.8 +/- 3.7, 5.9 +/- 3.1, and 6.1 +/- 2.7 micrograms.kg-1.min-1 for the groups receiving barbiturate-nitrous oxide-opioid, enflurane, and isoflurane anesthesia, respectively.	barbiturate-nitrous oxide-opioid	136-168	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
8466064-9	1993	CONCLUSIONS: The infusion requirements to maintain 95% twitch depression approximated 10 micrograms.kg-1.min-1 during barbiturate-nitrous oxide-opioid anesthesia.	barbiturate-nitrous oxide	118-143	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
8315800-5	1993	Then the fresh gas flow was reduced to oxygen 250 ml.min-1 and nitrous oxide 250 ml.min-1.	Nitrous Oxide	63-76	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
8514702-7	1993	For days 1 and 3 combined, total integrated areas for the glucose and insulin response curves averaged 1,683 mumol.ml-1.240 min-1 and 21,450 microU.ml-1.240 min-1, respectively.	Glucose	58-65	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
8514702-7	1993	For days 1 and 3 combined, total integrated areas for the glucose and insulin response curves averaged 1,683 mumol.ml-1.240 min-1 and 21,450 microU.ml-1.240 min-1, respectively.	Glucose	58-65	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
8473524-5	1993	Kinetic analysis revealed the PGI2 synthetic rate to be 14 ng/min-1 per million cells and t1/2 of PGI2 synthesis, 13.3 min.	Epoprostenol	30-34	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
8489699-6	1993	The KM value for methylglyoxal-glutathione hemithioacetal was 192 +/- 8 microM and the kcat value was 10.9 +/- 0.2 x 10(4) min-1 (N = 15).	methylglyoxal-glutathione hemithioacetal	17-57	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
8315800-6	1993	In order to maintain the inspired oxygen concentration at 35%, the flow of nitrous oxide should have been reduced as low as to 150 ml.min-1 after 240 min.	Oxygen	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
8315800-6	1993	In order to maintain the inspired oxygen concentration at 35%, the flow of nitrous oxide should have been reduced as low as to 150 ml.min-1 after 240 min.	Nitrous Oxide	75-88	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
8452256-5	1993	In the first study (n = 10), postoperative hypertension was controlled in the rewarming phase, with sodium nitroprusside (SNP, 1.7 +/- 0.4 micrograms.kg-1 x min-1) or adenosine (147.2 +/- 38.9 micrograms.kg-1 x min-1) to keep mean arterial systolic pressure at approximately 80 mm Hg.	Nitroprusside	100-120	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
7683151-4	1993	Digestion analyses with phosphatidylinositol-specific phospholipase C, an enzyme that releases GPI-anchored proteins from cell surfaces, showed that DAF and CD59 molecules with GPI anchors containing unacylated inositol were preferentially lost.	Phosphatidylinositols	24-44	CD59 molecule (CD59 blood group)	Homo sapiens	157-161
7683151-4	1993	Digestion analyses with phosphatidylinositol-specific phospholipase C, an enzyme that releases GPI-anchored proteins from cell surfaces, showed that DAF and CD59 molecules with GPI anchors containing unacylated inositol were preferentially lost.	GPI 1046	95-98	CD59 molecule (CD59 blood group)	Homo sapiens	157-161
7683151-4	1993	Digestion analyses with phosphatidylinositol-specific phospholipase C, an enzyme that releases GPI-anchored proteins from cell surfaces, showed that DAF and CD59 molecules with GPI anchors containing unacylated inositol were preferentially lost.	GPI 1046	177-180	CD59 molecule (CD59 blood group)	Homo sapiens	157-161
7683151-4	1993	Digestion analyses with phosphatidylinositol-specific phospholipase C, an enzyme that releases GPI-anchored proteins from cell surfaces, showed that DAF and CD59 molecules with GPI anchors containing unacylated inositol were preferentially lost.	Inositol	36-44	CD59 molecule (CD59 blood group)	Homo sapiens	157-161
7683151-5	1993	These findings suggest: 1) that DAF and CD59 molecules with acylated GPI anchors are more stable in RBC membranes than are molecules with unacylated GPI anchors, and 2) that DAF and CD59 loss may participate with other membrane alterations that occur during in vitro storage in compromising the survival of transfused cells.	GPI 1046	69-72	CD59 molecule (CD59 blood group)	Homo sapiens	40-44
8480475-6	1993	Insulin-stimulated (2 mU.kg-1 x min-1) glucose disposal rate tended to be increased (18%, p = 0.10) after dexfenfluramine.	Glucose	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	32-37
8480475-6	1993	Insulin-stimulated (2 mU.kg-1 x min-1) glucose disposal rate tended to be increased (18%, p = 0.10) after dexfenfluramine.	Dexfenfluramine	106-121	CD59 molecule (CD59 blood group)	Homo sapiens	32-37
8457055-9	1993	Continuous infusion of 300 micrograms.kg-1.min-1 of propofol appeared to provide satisfactory anesthesia in the ewe.	Propofol	52-60	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
8458192-8	1993	Although less marked, the same was also observed following acipimox (2.0 +/- 0.4 and 2.1 +/- 0.5 mg kg-1 min-1; both p &lt; 0.05).	acipimox	59-67	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
8471371-5	1993	Midazolam data were consistent with a three-compartment model with a mean (SD) elimination half-life of 107 (30) min, total body clearance of 15.4 (3.2) ml min-1 kg-1 and apparent volume of distribution at steady state of 1.9 (0.6) litre kg-1.	Midazolam	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	156-166
8471371-6	1993	Flumazenil data were best interpreted by a monoexponential function, with a mean terminal elimination half-life of 35.3 (13.8) min, a total plasma clearance of 20.6 (6.9) ml min-1 kg-1 and apparent volume of distribution at steady state of 1.0 (0.2) litre kg-1.	Flumazenil	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	174-184
8436742-8	1993	Myocardial blood flow after dipyridamole at PET1, PET2 and PET3 was 3.04 +/- 0.68, 3.00 +/- 0.71 and 3.00 +/- 0.60 ml.min-1 x g-1, respectively, in the remote region and 2.11 +/- 0.80 (p &lt; 0.01 vs. remote region), 2.28 +/- 0.73 (p = NS vs. remote region) and 3.06 +/- 0.86 ml.min-1 x g-1 (p = NS vs. remote region), respectively, in the angioplasty region.	Dipyridamole	28-40	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
8445040-7	1993	Again, rates of glucose metabolism were higher during IGF-1 infusion (11.8 +/- 1.2 vs 8.9 +/- 0.8 mg kg-1 min-1, p &lt; 0.01).	Glucose	16-23	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
8450473-2	1993	Kinetic determination of [3H]BMS 180,291 binding produced ligand-receptor association and dissociation rates of 1.4 x 10(7) +/- 0.2 M-1 x min-1 (n = 5) and 0.04 +/- 0.005 min-1 (n = 5), respectively.	Tritium	26-28	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
8470051-3	1993	Using the synthetic substrate EAY, substantial TPST activity (0.405 +/- 0.049 pmol EAY-SO4 formed min-1 mg-1) was detected in platelet homogenates.	eay-so4	83-90	CD59 molecule (CD59 blood group)	Homo sapiens	98-108
8470052-2	1993	Vehicle (5% glucose solution) or OKY-046 in 5% glucose solution at 15 micrograms kg-1 min-1 was intravenously administered to five male healthy volunteers for 6 h. Platelet aggregation and thromboxane B2 (TXB2) formation induced by collagen and arachidonic acid were suppressed by the infusion of OKY-046, while both were not affected by the infusion of vehicle.	ozagrel	33-40	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
7679927-4	1993	A solubilized preparation of the enzyme reconstituted with cytochrome P-450 reductase catalyzed the omega-hydroxylation of lauric acid, palmitic acid, and arachidonic acid with turnover numbers of 9.8, 2.2 and 0.55 min-1, respectively.	lauric acid	123-134	CD59 molecule (CD59 blood group)	Homo sapiens	215-220
7679927-4	1993	A solubilized preparation of the enzyme reconstituted with cytochrome P-450 reductase catalyzed the omega-hydroxylation of lauric acid, palmitic acid, and arachidonic acid with turnover numbers of 9.8, 2.2 and 0.55 min-1, respectively.	Palmitic Acid	136-149	CD59 molecule (CD59 blood group)	Homo sapiens	215-220
7679927-4	1993	A solubilized preparation of the enzyme reconstituted with cytochrome P-450 reductase catalyzed the omega-hydroxylation of lauric acid, palmitic acid, and arachidonic acid with turnover numbers of 9.8, 2.2 and 0.55 min-1, respectively.	Arachidonic Acid	155-171	CD59 molecule (CD59 blood group)	Homo sapiens	215-220
8429040-7	1993	For inhibition by antithrombin III with heparin, the rate constant was 4.5 x 10(8) M-1 min-1 for wild-type thrombin with no significant differences between any of the recombinant thrombins.	Heparin	40-47	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
8429040-8	1993	In contrast, the rate constant for inhibition by heparin cofactor II without glycosaminoglycan was 4.3 x 10(4) M-1 min-1 for wild-type thrombin; rates were 10-fold slower for thrombin K52E and 2- to 3-fold slower for thrombins R68E and R70E.	Heparin	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
8429040-9	1993	The rate constants for inhibition of wild-type thrombin by HCII in the presence of heparin or dermatan sulfate were 9.2 x 10(8) M-1 min-1 and 9.0 x 10(8) M-1 min-1, respectively.	Heparin	83-90	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
8429040-9	1993	The rate constants for inhibition of wild-type thrombin by HCII in the presence of heparin or dermatan sulfate were 9.2 x 10(8) M-1 min-1 and 9.0 x 10(8) M-1 min-1, respectively.	Dermatan Sulfate	94-110	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
8429040-9	1993	The rate constants for inhibition of wild-type thrombin by HCII in the presence of heparin or dermatan sulfate were 9.2 x 10(8) M-1 min-1 and 9.0 x 10(8) M-1 min-1, respectively.	Dermatan Sulfate	94-110	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
8430629-7	1993	Heart rate variations during coronary arteriography were 4 +/- 3 min-1 at baseline and 5 +/- 4 min-1 after papaverine administration.	Papaverine	107-117	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
8470783-4	1993	In both cases we observed a short episode of bradycardia (heart rate &lt; 50.min-1), which was successfully treated with atropine.	Atropine	121-129	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
8095150-3	1993	Peak heart rate (mean and 95% confidence intervals) was lower (P &lt; 0.05) with epanolol (121 (115-130) beats min-1) than with diltiazem (137 (126-148) beats min-1) or placebo (141 (130-152) beats min-1).	epanolol	81-89	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
8443035-9	1993	Inhalation of increasing doses of histamine through a nebuliser (output 0.13 ml min-1) resulted in an increase from a mean of 0.30 to 1.65 ng ml-1, with return towards baseline within 20 min.	Histamine	34-43	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
8443035-13	1993	Histamine excretion rate increased by 108 ng min-1 (P = 0.04) after inhalation and by 37.2 ng min-1 (P = 0.09) after injection.	Histamine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
8504458-2	1993	Keeping the fluorescence intensities at low levels, regular oscillations of [Ca2+]i with a frequency of 0.2-0.5 min-1 could be recorded for more than 60 min in glucose-stimulated cells.	Glucose	160-167	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
8382588-2	1993	The effect of a single dose of lithium on renal function before and during intravenous infusion of dopamine (3 micrograms min-1 kg-1) was investigated in 12 healthy males.	Dopamine	99-107	CD59 molecule (CD59 blood group)	Homo sapiens	122-132
8425663-5	1993	Insulin-stimulated GDRs at a plasma insulin concentration of approximately 450 pM averaged 45.6 +/- 3.3 mumol.kg FFM-1 x min-1 (mean +/- SE) in the young subjects, 45.6 +/- 10.0 mumol.kg FFM-1 x min-1 in 24 older subjects who were insulin sensitive, and 23.9 +/- 11.7 mumol.kg FFM-1 x min-1 in 43 older subjects who were insulin resistant.	gdrs	19-23	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
8458523-4	1993	Endogenous glucose production ([6-3H]glucose) was greater in diabetic than control subjects in the post-absorptive state (15.6 +/- 1.5 vs 11.3 +/- 0.4 mumol.kg-1 x min-1, p &lt; 0.05) and during the 0.4 mU insulin infusion (10.1 +/- 1.3 vs 5.2 +/- 0.3 mumol.kg-1 x min-1, p &lt; 0.01) indicating hepatic insulin resistance.	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
8458523-4	1993	Endogenous glucose production ([6-3H]glucose) was greater in diabetic than control subjects in the post-absorptive state (15.6 +/- 1.5 vs 11.3 +/- 0.4 mumol.kg-1 x min-1, p &lt; 0.05) and during the 0.4 mU insulin infusion (10.1 +/- 1.3 vs 5.2 +/- 0.3 mumol.kg-1 x min-1, p &lt; 0.01) indicating hepatic insulin resistance.	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	265-270
8458523-5	1993	Glucose/glucose 6-phosphate cycling was significantly greater in diabetic than in control subjects in the post-absorptive state (2.6 +/- 0.4 vs 1.6 +/- 0.2 mumol.kg-1 x min-1, p &lt; 0.05) but not during the 0.4 mU insulin infusion (2.0 +/- 0.4 vs 2.0 +/- 0.3 mumol.kg-1 x min-1).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
8458523-5	1993	Glucose/glucose 6-phosphate cycling was significantly greater in diabetic than in control subjects in the post-absorptive state (2.6 +/- 0.4 vs 1.6 +/- 0.2 mumol.kg-1 x min-1, p &lt; 0.05) but not during the 0.4 mU insulin infusion (2.0 +/- 0.4 vs 2.0 +/- 0.3 mumol.kg-1 x min-1).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	273-278
8432860-8	1993	Insulin increased k(in) of MeAIB from a basal value of 11.8.10(-2) +/- 1.7.10(-2).min-1 to 13.7.10(-2) +/- 2.2.10(-2).min-1 (P &lt; 0.02 vs the postabsorptive value), whereas kout was unchanged.	2,2-dimethyl-beta-alanine	27-32	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
8432860-8	1993	Insulin increased k(in) of MeAIB from a basal value of 11.8.10(-2) +/- 1.7.10(-2).min-1 to 13.7.10(-2) +/- 2.2.10(-2).min-1 (P &lt; 0.02 vs the postabsorptive value), whereas kout was unchanged.	2,2-dimethyl-beta-alanine	27-32	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
7688808-9	1993	When the cerebellum supernatant was chelated with EDTA, the production of cyclic GMP was lowered to a level of 7 nmol min-1 (g tissue)-1 and the radiation effect was not found.	Edetic Acid	50-54	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
7688808-11	1993	Incubation with Methylene Blue, a guanylate cyclase inhibitor, lowered the production of cyclic GMP to a level of 10-12 nmol min-1 (g tissue)-1, and the radiation effect did not occur.	Methylene Blue	16-30	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
7688808-12	1993	On incubation with a NO synthase inhibitor, either NG-methyl-L-arginine or N omega-nitro-L-arginine methyl ester, the production of cyclic GMP was lowered to a level of 10-12 nmol min-1 (g tissue)-1 or 5-9 nmol min-1 (g tissue)-1 respectively, and the radiation effect was not observed.	ng-methyl-l-arginine	51-71	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
7688808-12	1993	On incubation with a NO synthase inhibitor, either NG-methyl-L-arginine or N omega-nitro-L-arginine methyl ester, the production of cyclic GMP was lowered to a level of 10-12 nmol min-1 (g tissue)-1 or 5-9 nmol min-1 (g tissue)-1 respectively, and the radiation effect was not observed.	ng-methyl-l-arginine	51-71	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
7688808-12	1993	On incubation with a NO synthase inhibitor, either NG-methyl-L-arginine or N omega-nitro-L-arginine methyl ester, the production of cyclic GMP was lowered to a level of 10-12 nmol min-1 (g tissue)-1 or 5-9 nmol min-1 (g tissue)-1 respectively, and the radiation effect was not observed.	NG-Nitroarginine Methyl Ester	75-112	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
7688808-12	1993	On incubation with a NO synthase inhibitor, either NG-methyl-L-arginine or N omega-nitro-L-arginine methyl ester, the production of cyclic GMP was lowered to a level of 10-12 nmol min-1 (g tissue)-1 or 5-9 nmol min-1 (g tissue)-1 respectively, and the radiation effect was not observed.	NG-Nitroarginine Methyl Ester	75-112	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
8450583-4	1993	For the entire ski trip, the mean HR during skiing was approximately 126 beats min-1, which corresponds to 75% THRmax.	thrmax	111-117	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
8437352-4	1993	PGE1 increased urine output and creatinine clearance (Ccr) during hypotension in dose dependent manner, and the changes were statistically significant compared with control at the dose of 0.02 micrograms.kg-1 x min-1 (gamma).	Alprostadil	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
8465173-2	1993	During toluene exposure to 2 mg.min-1 for 3 h the alveolar toluene concentration was 0.07 (range 0-0.11) mg.m-3; exposure to 6 mg.min-1 for 30 min increased the alveolar concentration to 0.9 (range 0.03-2.6) mg.m-3.	Toluene	7-14	CD59 molecule (CD59 blood group)	Homo sapiens	32-37
8465173-2	1993	During toluene exposure to 2 mg.min-1 for 3 h the alveolar toluene concentration was 0.07 (range 0-0.11) mg.m-3; exposure to 6 mg.min-1 for 30 min increased the alveolar concentration to 0.9 (range 0.03-2.6) mg.m-3.	Toluene	7-14	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
8465173-2	1993	During toluene exposure to 2 mg.min-1 for 3 h the alveolar toluene concentration was 0.07 (range 0-0.11) mg.m-3; exposure to 6 mg.min-1 for 30 min increased the alveolar concentration to 0.9 (range 0.03-2.6) mg.m-3.	Toluene	59-66	CD59 molecule (CD59 blood group)	Homo sapiens	32-37
8465173-2	1993	During toluene exposure to 2 mg.min-1 for 3 h the alveolar toluene concentration was 0.07 (range 0-0.11) mg.m-3; exposure to 6 mg.min-1 for 30 min increased the alveolar concentration to 0.9 (range 0.03-2.6) mg.m-3.	Toluene	59-66	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
8465173-3	1993	Ingestion of 0.08, 0.16, and 0.32 g of ethanol per kilogram of body weight during toluene exposure of 2 mg.min-1 increased the alveolar concentration within 10 min, and maximal alveolar concentrations of 5 (SD 3), 24 (SD 11), and 39 (SD 28) mg.m-3 were reached after 30, 60, and 90 min for the three doses, respectively.	Ethanol	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
8465173-3	1993	Ingestion of 0.08, 0.16, and 0.32 g of ethanol per kilogram of body weight during toluene exposure of 2 mg.min-1 increased the alveolar concentration within 10 min, and maximal alveolar concentrations of 5 (SD 3), 24 (SD 11), and 39 (SD 28) mg.m-3 were reached after 30, 60, and 90 min for the three doses, respectively.	Toluene	82-89	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
8416918-3	1993	By displacement experiments a dissociation rate constant of 2.9 (+/- 0.6) x 10(-2) min-1 was determined at 25 degrees C. The effect of 3",4",5"-trimethoxyacetophenone (TMA) is 2-fold.	3',4',5'-trimethoxyacetophenone	135-166	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
8416918-3	1993	By displacement experiments a dissociation rate constant of 2.9 (+/- 0.6) x 10(-2) min-1 was determined at 25 degrees C. The effect of 3",4",5"-trimethoxyacetophenone (TMA) is 2-fold.	3',4',5'-trimethoxyacetophenone	168-171	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
8430789-4	1993	Basal endogenous glucose production increased during gestation [Ctl: P 2.74 +/- 0.23, E 2.62 +/- 0.38, and L 3.14 +/- 0.36; GDM: P 2.68 +/- 0.51, E 2.78 +/- 0.45, and L 2.98 +/- 0.48 mg.kg fat-free mass (FFM)-1 x min-1; P = 0.02], but there was resistance to suppression by insulin infusion (P = 0.03) in late gestation (GDM: 0.61 +/- 0.44 vs. Ctl: 0.16 +/- 0.17 mg.kg FFM-1 x min-1).	Glucose	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	377-382
8430789-4	1993	Basal endogenous glucose production increased during gestation [Ctl: P 2.74 +/- 0.23, E 2.62 +/- 0.38, and L 3.14 +/- 0.36; GDM: P 2.68 +/- 0.51, E 2.78 +/- 0.45, and L 2.98 +/- 0.48 mg.kg fat-free mass (FFM)-1 x min-1; P = 0.02], but there was resistance to suppression by insulin infusion (P = 0.03) in late gestation (GDM: 0.61 +/- 0.44 vs. Ctl: 0.16 +/- 0.17 mg.kg FFM-1 x min-1).	Glucose	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	213-218
7687835-10	1993	To maintain a mean blood pressure of a least 50 mmHg, an infusion of up to 10 micrograms.kg-1 x min-1 of phenylephrine was given.	Phenylephrine	105-118	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
7687835-11	1993	As it was insufficient, an infusion of up to 1 microgram.kg-1 x min-1 noradrenaline was required.	Norepinephrine	70-83	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
8220264-3	1993	It hydrolyzed bradykinin at the Phe5-Ser6 peptide bond at a rate of 1.090 mumol min-1 mg protein-1 at pH 8.0 and 37 degrees C. The molecular weight of this endopeptidase H2, estimated by SDS-polyacrylamide gel electrophoresis and by gel filtration, was 60 kDa, and its optimum pH for bradykinin hydrolysis was near 8.5.	Sodium Dodecyl Sulfate	187-190	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
8338258-6	1993	The dopamine bolus generated by CVP measurement was equivalent to a dose of 85 micrograms.kg-1 x min-1.	Dopamine	4-12	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
8427942-7	1993	Hymecromone"s total body clearance averaged 1413 +/- 89 ml min-1.	Hymecromone	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
8448066-10	1993	were 8.9 +/- 1.6 and 9.1 +/- 2.0 mg kg-1 min-1 after single doses of lacidipine and placebo respectively (95% CI, -1.0, 1.3), and correspondingly 9.6 +/- 2.1 and 9.7 +/- 1.5 mg kg-1 min-1 after 2 weeks (95% CI, -1.0, 1.3).	lacidipine	69-79	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
8220264-3	1993	It hydrolyzed bradykinin at the Phe5-Ser6 peptide bond at a rate of 1.090 mumol min-1 mg protein-1 at pH 8.0 and 37 degrees C. The molecular weight of this endopeptidase H2, estimated by SDS-polyacrylamide gel electrophoresis and by gel filtration, was 60 kDa, and its optimum pH for bradykinin hydrolysis was near 8.5.	polyacrylamide	191-205	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
8435988-2	1993	Glucose disposal (assessed by the euglycaemic insulin clamp technique) was significantly reduced in diabetic patients compared to control subjects (4.4 +/- 0.5 vs 6.4 +/- 0.5 mg kg-1 min-1, p &lt; 0.05), and increased after 1 and 3 months of sulphonylurea therapy to 6.8 +/- 0.6 mg kg-1 min-1 (p = 0.01) and 6.3 +/- 0.7 mg kg-1 min-1 (p = 0.04), respectively.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
8269597-4	1993	Patients who received phenytoin demonstrated significantly higher clearance (mean +/- SD, 3.32 +/- 0.99 ml min-1 kg-1), a lower area under the concentration-time curve (AUC, 5,412 +/- 1,534 ng h ml-1; corrected for dose/kilogram) and a shorter elimination half-life (3.03 +/- 0.57 h) for the last dose of d8-BU (dose 16) as compared with the first dose (2.80 +/- 0.78 ml min-1 kg-1, 6,475 +/- 2,223 ng h ml-1 and 3.94 +/- 1.10 h, respectively).	Phenytoin	22-31	CD59 molecule (CD59 blood group)	Homo sapiens	107-117
8269597-4	1993	Patients who received phenytoin demonstrated significantly higher clearance (mean +/- SD, 3.32 +/- 0.99 ml min-1 kg-1), a lower area under the concentration-time curve (AUC, 5,412 +/- 1,534 ng h ml-1; corrected for dose/kilogram) and a shorter elimination half-life (3.03 +/- 0.57 h) for the last dose of d8-BU (dose 16) as compared with the first dose (2.80 +/- 0.78 ml min-1 kg-1, 6,475 +/- 2,223 ng h ml-1 and 3.94 +/- 1.10 h, respectively).	Phenytoin	22-31	CD59 molecule (CD59 blood group)	Homo sapiens	371-381
8435988-2	1993	Glucose disposal (assessed by the euglycaemic insulin clamp technique) was significantly reduced in diabetic patients compared to control subjects (4.4 +/- 0.5 vs 6.4 +/- 0.5 mg kg-1 min-1, p &lt; 0.05), and increased after 1 and 3 months of sulphonylurea therapy to 6.8 +/- 0.6 mg kg-1 min-1 (p = 0.01) and 6.3 +/- 0.7 mg kg-1 min-1 (p = 0.04), respectively.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	287-292
8435988-2	1993	Glucose disposal (assessed by the euglycaemic insulin clamp technique) was significantly reduced in diabetic patients compared to control subjects (4.4 +/- 0.5 vs 6.4 +/- 0.5 mg kg-1 min-1, p &lt; 0.05), and increased after 1 and 3 months of sulphonylurea therapy to 6.8 +/- 0.6 mg kg-1 min-1 (p = 0.01) and 6.3 +/- 0.7 mg kg-1 min-1 (p = 0.04), respectively.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	287-292
8223521-6	1993	The highest significant correlations were found among IP4000 and the following: VO2max (ml.kg-2/3.min-1; r = -0.79), power output at lactate threshold (Wthla) (W; r = -0.86), half time of VO2 response whilst cycling at 115% VO2max (s; r = 0.48) and MAOD when assessed using the 5 min protocol (ml.kg-1; r = -0.50).	ip4000	54-60	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
8504885-7	1993	The mean glucose infusion rate during the clamp was low in the diabetic girls (2.29 +/- 1.35 mg kg-1 min-1), confirming the existence of insulin resistance.	Glucose	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
8223352-4	1993	Enoximone resulted in reduced filling pressures (P &lt; 0.005) and improved cardiac index (before enoximone, 0.96 litres min-1 m-2; after enoximone, 3.05 litres min-1 m-2; P &lt; 0.001).	Enoximone	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
8223352-4	1993	Enoximone resulted in reduced filling pressures (P &lt; 0.005) and improved cardiac index (before enoximone, 0.96 litres min-1 m-2; after enoximone, 3.05 litres min-1 m-2; P &lt; 0.001).	Enoximone	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
8375364-7	1993	Results from the CE tests revealed a significant Thv increase (P &lt; 0.01) for the CT group [566 (663) ml O2 x min-1] with no change for the RT group.	Carbon Tetrachloride	84-86	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
8375364-6	1993	Significant Thv increases (P &lt; 0.05) were found on TM tests for RT (n = 8) and CT (n = 8) groups [mean (SD); 443 (438) and 373 (568) ml O2 x min-1, respectively] with no difference between the groups.	THV	12-15	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
8472690-2	1993	Exercise of 6-min duration at a power output equivalent to 92 (SD 5)% maximal oxygen uptake (VO2max), whether performed at a pedalling frequency of 60 or 120 rev.min-1, reduced maximal STPO generated at 120 rev.min-1 to a much greater extent than maximal STPO at 60 rev.min-1.	Oxygen	78-84	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
8375364-7	1993	Results from the CE tests revealed a significant Thv increase (P &lt; 0.01) for the CT group [566 (663) ml O2 x min-1] with no change for the RT group.	THV	49-52	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
8472690-6	1993	Nevertheless, maximal STPO generated at 120 rev.min-1 was reduced after exercise at 120 rev.min-1 [20 (SD 13)%, P &lt; 0.05] whereas no significant reduction in maximal STPO was found after prior exercise at 60 rev.min-1.	stpo	22-26	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
8495694-9	1993	The only significant difference was observed for fc: 198 (SD 11) beats.min-1 in DP and 187 (SD 11) beats.min-1 in JMP.	dp	80-82	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
8472690-6	1993	Nevertheless, maximal STPO generated at 120 rev.min-1 was reduced after exercise at 120 rev.min-1 [20 (SD 13)%, P &lt; 0.05] whereas no significant reduction in maximal STPO was found after prior exercise at 60 rev.min-1.	stpo	22-26	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
8472690-6	1993	Nevertheless, maximal STPO generated at 120 rev.min-1 was reduced after exercise at 120 rev.min-1 [20 (SD 13)%, P &lt; 0.05] whereas no significant reduction in maximal STPO was found after prior exercise at 60 rev.min-1.	stpo	22-26	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
8112373-3	1993	Nicorandil was infused for 12 h in 21 healthy volunteers at rates of 0.05, 0.10, and 0.20 microgram.kg-1.min-1 using a placebo controlled, crossover design.	Nicorandil	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
7901024-3	1993	Following IV administration, the plasma clearance of fenspiride was about 184 ml.min-1, and its apparent volume of distribution was moderately large (215 l).	fenspiride	53-63	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
8112373-6	1993	Four 0.20 microgram.kg-1.min-1 nicorandil infusions were terminated early primarily because of moderate or severe headaches.	Nicorandil	31-41	CD59 molecule (CD59 blood group)	Homo sapiens	25-30
8223833-1	1993	Nitrendipine solution 5 mg.ml-1 in the dose of 5 mg was given orally to 20 patients with chronic renal failure and elevated diastolic blood pressure (&gt; or = 110 mmHg), of whom 10 were on maintenance haemodialysis (endogenous creatinine clearance &lt; 5 ml.min-1) and 10 were at the predialysis stage (endogenous creatinine clearance 5-20 ml.min-1).	Nitrendipine	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	259-264
8223833-1	1993	Nitrendipine solution 5 mg.ml-1 in the dose of 5 mg was given orally to 20 patients with chronic renal failure and elevated diastolic blood pressure (&gt; or = 110 mmHg), of whom 10 were on maintenance haemodialysis (endogenous creatinine clearance &lt; 5 ml.min-1) and 10 were at the predialysis stage (endogenous creatinine clearance 5-20 ml.min-1).	Nitrendipine	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	344-349
8359193-2	1993	As the dose in the 1 min infusion study was increased the mean CL of adenosine decreased (10.7, 4.70 and 4.14 l.min-1, respectively), its mean half-life increased (0.91, 1.24 and 1.86 min, respectively), and the mean volume of distribution did not show any clear trend (8-13 l).	Adenosine	69-78	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
8359193-3	1993	After the 20 minute infusion the plasma level of adenosine reached a peak value comparable to that observed after infusion of 5 mg in 1 min (about 0.5 micrograms.ml-1), but the mean clearance and half-life were significantly different (12.1 l.min-1 and 0.63 min respectively).	Adenosine	49-58	CD59 molecule (CD59 blood group)	Homo sapiens	243-248
8436154-2	1993	NTG 0.5 microgram.kg-1 x min-1 or saline were infused i.v.	Nitroglycerin	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	25-30
8436159-7	1993	Pindolol showed beta-adrenoceptor antagonistic effects in the supine position through decrements in heart rate from 70 to 66 beats.min-1 and LVEF from 0.57 to 0.52, and reduced mean arterial blood pressure from 103 mm Hg to 93 mm Hg.	Pindolol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
8436159-8	1993	Xamoterol showed beta-adrenoceptor agonistic effects in the supine position through increments in heart rate from 72 to 90 beats.min-1 and LVEF from 0.58 to 0.66, and raised mean arterial blood pressure from 108 to 123 mm Hg.	Xamoterol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
8444274-1	1993	It has recently been demonstrated that the infusion of a high caloric load (3.3 kcal min-1 = 14.0 kJ min-1) into human upper jejunum inhibited pancreatic enzyme and bile salt secretion.	Bile Acids and Salts	165-174	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
8444274-1	1993	It has recently been demonstrated that the infusion of a high caloric load (3.3 kcal min-1 = 14.0 kJ min-1) into human upper jejunum inhibited pancreatic enzyme and bile salt secretion.	Bile Acids and Salts	165-174	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
7689003-1	1993	CD59 (leukocyte cluster of differentiation antigen 59), is a phosphatidylinositol glycan-anchored membrane protein that inhibits lysis of cells by terminal complement system components.	Phosphatidylinositols	61-81	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
7689003-1	1993	CD59 (leukocyte cluster of differentiation antigen 59), is a phosphatidylinositol glycan-anchored membrane protein that inhibits lysis of cells by terminal complement system components.	Phosphatidylinositols	61-81	CD59 molecule (CD59 blood group)	Homo sapiens	16-53
7678023-5	1993	In the present study, we found that the epitopes of HRF20 were well preserved for immunohistochemistry even in acetone-fixed and paraffin-embedded tissues, as well as in frozen tissues that have been conventionally used for HRF20.	Acetone	111-118	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
7678023-5	1993	In the present study, we found that the epitopes of HRF20 were well preserved for immunohistochemistry even in acetone-fixed and paraffin-embedded tissues, as well as in frozen tissues that have been conventionally used for HRF20.	Paraffin	129-137	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
8433497-2	1993	These patients ranging in ages from 24 to 80 years were administered intravenous isosorbide dinitrate at a rate of either 0.5 or 1 microgram.kg-1 x min-1 during anesthesia and surgery.	Isosorbide Dinitrate	81-101	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
8433497-4	1993	The arterial pressure of the patients decreased slightly but significantly 30 min after the start of 1 microgram.kg-1 x min-1 of isosorbide dinitrate infusion, but it recovered to the control level at the end of administration of isosorbide dinitrate.	Isosorbide Dinitrate	129-149	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
8433497-7	1993	Significant improvement of ischemic changes on ECG tracings were observed in about 25% of the patients who received 1 micrograms.kg-1 x min-1 of intravenous isosorbide dinitrate.	Isosorbide Dinitrate	157-177	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
7507222-2	1993	The tumor promoting phorbol ester TPA induced a marked up-regulation of protectin in all examined cell lines with the exception of promyelocytic leukemia HL-60, where TPA significantly decreased protectin cell surface expression.	Phorbol Esters	20-33	CD59 molecule (CD59 blood group)	Homo sapiens	72-81
7507222-2	1993	The tumor promoting phorbol ester TPA induced a marked up-regulation of protectin in all examined cell lines with the exception of promyelocytic leukemia HL-60, where TPA significantly decreased protectin cell surface expression.	Phorbol Esters	20-33	CD59 molecule (CD59 blood group)	Homo sapiens	195-204
7507222-2	1993	The tumor promoting phorbol ester TPA induced a marked up-regulation of protectin in all examined cell lines with the exception of promyelocytic leukemia HL-60, where TPA significantly decreased protectin cell surface expression.	Tetradecanoylphorbol Acetate	34-37	CD59 molecule (CD59 blood group)	Homo sapiens	72-81
7507222-2	1993	The tumor promoting phorbol ester TPA induced a marked up-regulation of protectin in all examined cell lines with the exception of promyelocytic leukemia HL-60, where TPA significantly decreased protectin cell surface expression.	Tetradecanoylphorbol Acetate	34-37	CD59 molecule (CD59 blood group)	Homo sapiens	195-204
7507222-2	1993	The tumor promoting phorbol ester TPA induced a marked up-regulation of protectin in all examined cell lines with the exception of promyelocytic leukemia HL-60, where TPA significantly decreased protectin cell surface expression.	Tetradecanoylphorbol Acetate	167-170	CD59 molecule (CD59 blood group)	Homo sapiens	195-204
7507222-3	1993	All-trans retinoic acid weakly down-regulated cell surface protectin on K-562, while 1,25(OH)2-vitamin D3 produced such effect on HL-60 cells.	2-octenal	4-9	CD59 molecule (CD59 blood group)	Homo sapiens	59-68
7507222-3	1993	All-trans retinoic acid weakly down-regulated cell surface protectin on K-562, while 1,25(OH)2-vitamin D3 produced such effect on HL-60 cells.	Tretinoin	10-23	CD59 molecule (CD59 blood group)	Homo sapiens	59-68
8446180-5	1993	Intravenous infusion of noradrenaline (5 micrograms.kg-1.min-1) elicited a pronounced pressor response which was also associated with a decrease in the release of noradrenaline in the locus coeruleus.	Norepinephrine	24-37	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
8446180-5	1993	Intravenous infusion of noradrenaline (5 micrograms.kg-1.min-1) elicited a pronounced pressor response which was also associated with a decrease in the release of noradrenaline in the locus coeruleus.	Norepinephrine	163-176	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
8446180-7	1993	A profound fall in blood pressure caused by infusion of nitroprusside (8 micrograms.kg-1.min-1) did not modify the release rate of noradrenaline.	Nitroprusside	56-69	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
8415545-3	1993	The pH optimum for oxaloacetate reduction was 6.1, with maximal activity at 7811 nmol min-1 mg protein-1, but high concentrations of oxaloacetate inhibited MDH activity.	Oxaloacetic Acid	19-31	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
1334428-7	1992	Km and Vmax for two substrates, src-related peptide and poly(Glu, Tyr) (4:1), were 2.4 mM and 2.5 mumol min-1 mg-1 and 0.26 mM and 1.2 mumol min-1 mg-1, respectively.	poly(glu,	56-65	CD59 molecule (CD59 blood group)	Homo sapiens	104-114
1334428-7	1992	Km and Vmax for two substrates, src-related peptide and poly(Glu, Tyr) (4:1), were 2.4 mM and 2.5 mumol min-1 mg-1 and 0.26 mM and 1.2 mumol min-1 mg-1, respectively.	poly(glu,	56-65	CD59 molecule (CD59 blood group)	Homo sapiens	141-151
1334428-7	1992	Km and Vmax for two substrates, src-related peptide and poly(Glu, Tyr) (4:1), were 2.4 mM and 2.5 mumol min-1 mg-1 and 0.26 mM and 1.2 mumol min-1 mg-1, respectively.	Tyrosine	66-70	CD59 molecule (CD59 blood group)	Homo sapiens	104-114
1334428-7	1992	Km and Vmax for two substrates, src-related peptide and poly(Glu, Tyr) (4:1), were 2.4 mM and 2.5 mumol min-1 mg-1 and 0.26 mM and 1.2 mumol min-1 mg-1, respectively.	Tyrosine	66-70	CD59 molecule (CD59 blood group)	Homo sapiens	141-151
1334075-8	1992	This effect (IC50,Tg = 0.45 +/- 0.06 microM), together with a 24 +/- 16% increase in kleak,PM,Ca (to 3 x 10(-4) min-1), accounts for a Tg-dependent sustained elevation [Ca2+]cyt (to 708 +/- 78 nM) which is independent of DT Ca2+ status or history.	Thapsigargin	18-20	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
1336317-2	1992	The inotropic response induced by isoproterenol (isoprenaline, 20 ng.kg-1 x min-1), measured by m-mode echocardiography as the increase of fractional shortening in seven healthy subjects, was reduced from 17.1 +/- 4.3 to 9.1 +/- 3.9% (P &lt; 0.01) by M-cholinoceptor stimulation using intravenous injection of 3.6 micrograms/kg carbachol.	Isoproterenol	34-47	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
1336317-2	1992	The inotropic response induced by isoproterenol (isoprenaline, 20 ng.kg-1 x min-1), measured by m-mode echocardiography as the increase of fractional shortening in seven healthy subjects, was reduced from 17.1 +/- 4.3 to 9.1 +/- 3.9% (P &lt; 0.01) by M-cholinoceptor stimulation using intravenous injection of 3.6 micrograms/kg carbachol.	Isoproterenol	49-61	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
1336317-3	1992	However, the inotropic response of increasing doses of isoprenaline (5-20 ng.kg-1 x min-1) did not differ in 13 healthy subjects without and after M-cholinoceptor blockade (atropine, 0.015 mg/kg i.v.	Isoproterenol	55-67	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
1336317-4	1992	); the increase of fractional shortening amounted to 17.4 +/- 4.0 vs. 19.5 +/- 4.8% (NS) in response to 20 ng.kg-1 x min-1 isoprenaline.	Nitrogen	85-87	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
1336317-4	1992	); the increase of fractional shortening amounted to 17.4 +/- 4.0 vs. 19.5 +/- 4.8% (NS) in response to 20 ng.kg-1 x min-1 isoprenaline.	Isoproterenol	123-135	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
1359809-7	1992	The infusion regimens of dexmedetomidine tested in the dose-response study ranged from 120 ng.kg-1 x min-1, followed by 6 ng.kg-1 x min-1, to 270 + 13.5 ng.kg-1 x min-1.	Dexmedetomidine	25-40	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
1449301-11	1992	Mean lactate consumption 5 minutes after reperfusion was significantly greater (p = 0.0001) in group 1 (31.8 +/- 6.3 micrograms.min-1 x g-1) than in group 2 (-0.59 +/- 0.1 microgram.min-1 x g-1), indicating superior metabolic recovery in the blood cardioplegia hearts.	Lactic Acid	5-12	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
1449301-11	1992	Mean lactate consumption 5 minutes after reperfusion was significantly greater (p = 0.0001) in group 1 (31.8 +/- 6.3 micrograms.min-1 x g-1) than in group 2 (-0.59 +/- 0.1 microgram.min-1 x g-1), indicating superior metabolic recovery in the blood cardioplegia hearts.	Lactic Acid	5-12	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
1468165-4	1992	51Cr EDTA GFR rose significantly from baseline after the combination of indomethacin and misoprostol (from mean +/- SD 117 +/- 7.1 to 123 +/- 8.0 mls/min/1.73 m2, p = 0.05).	51cr edta	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
1468165-4	1992	51Cr EDTA GFR rose significantly from baseline after the combination of indomethacin and misoprostol (from mean +/- SD 117 +/- 7.1 to 123 +/- 8.0 mls/min/1.73 m2, p = 0.05).	Indomethacin	72-84	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
1468165-4	1992	51Cr EDTA GFR rose significantly from baseline after the combination of indomethacin and misoprostol (from mean +/- SD 117 +/- 7.1 to 123 +/- 8.0 mls/min/1.73 m2, p = 0.05).	Misoprostol	89-100	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
1468165-6	1992	However in 4 of these subjects 51Cr EDTA GFR fell (range 7-19 mls/min/1.73 m2); in each of these the reduction was reversed when the indomethacin was given together with misoprostol.	Indomethacin	133-145	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
1468165-6	1992	However in 4 of these subjects 51Cr EDTA GFR fell (range 7-19 mls/min/1.73 m2); in each of these the reduction was reversed when the indomethacin was given together with misoprostol.	Misoprostol	170-181	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
1468165-7	1992	In the whole group the change in 51Cr EDTA GFR, from baseline, after indomethacin plus misoprostol was significantly different from that after indomethacin alone (+6 +/- 8 vs -3 +/- 5 mls/min/1.73 m2 p = 0.05).	Indomethacin	69-81	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
1468165-7	1992	In the whole group the change in 51Cr EDTA GFR, from baseline, after indomethacin plus misoprostol was significantly different from that after indomethacin alone (+6 +/- 8 vs -3 +/- 5 mls/min/1.73 m2 p = 0.05).	Misoprostol	87-98	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
1478365-8	1992	Stimulation of glucose disposal by insulin was reduced in hypertriglyceridaemic vs normotriglyceridaemic patients (27.0 +/- 1.3 vs 31.9 +/- 1.6 mumol.kg-1 x min-1; p &lt; 0.05) primarily due to impaired glucose storage (9.8 +/- 1.0 vs 14.6 +/- 1.4 mumol.kg-1 x min-1; p &lt; 0.01).	Glucose	15-22	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
1478365-8	1992	Stimulation of glucose disposal by insulin was reduced in hypertriglyceridaemic vs normotriglyceridaemic patients (27.0 +/- 1.3 vs 31.9 +/- 1.6 mumol.kg-1 x min-1; p &lt; 0.05) primarily due to impaired glucose storage (9.8 +/- 1.0 vs 14.6 +/- 1.4 mumol.kg-1 x min-1; p &lt; 0.01).	Glucose	15-22	CD59 molecule (CD59 blood group)	Homo sapiens	261-266
1280224-5	1992	DAF and CD59 were released from the surface of HUVEC by phosphatidylinositol-phospholipase C, demonstrating that both are attached to the cell membrane by means of a glycolipid anchor.	Glycolipids	166-176	CD59 molecule (CD59 blood group)	Homo sapiens	8-12
1289100-3	1992	Nisoldipine was administered as a 4.5 micrograms kg-1 intravenous bolus over 3 min followed by intravenous infusion of 0.2 microgram kg-1 min-1 during 60 min.	Nisoldipine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
1283697-2	1992	Unexpectedly, treatment of R(DAF+/CD59+) cells with Mg2(+)-EGTA-serum resulted in efficient C3 deposition, while treatment of R(DAF-/CD59-) cells did not.	mg2(+)	52-58	CD59 molecule (CD59 blood group)	Homo sapiens	34-38
1443116-2	1992	After a control period, epinephrine was infused at rates of 0.2 and 0.4 nmol.kg-1 x min-1.	Epinephrine	24-35	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
1443116-6	1992	Local forearm oxygen uptake was 3.9 +/- 1.3 mumol.100 g-1 x min-1 in the basal period.	Oxygen	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
1443116-8	1992	Local forearm glucose uptake was 0.160 +/- 0.105 mumol.100 g-1 x min-1 and increased to 0.586 +/- 0.445 and 0.760 +/- 0.534 mumol.100 g-1 x min-1 (P &lt; 0.025).	Glucose	14-21	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
1443116-8	1992	Local forearm glucose uptake was 0.160 +/- 0.105 mumol.100 g-1 x min-1 and increased to 0.586 +/- 0.445 and 0.760 +/- 0.534 mumol.100 g-1 x min-1 (P &lt; 0.025).	Glucose	14-21	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
1443120-4	1992	Postabsorptive phenylalanine rate of appearance (R(a)) in NIDDM (0.63 +/- 0.08 mumol.kg-1 x min-1) was comparable to that of controls (0.73 +/- 0.05 mumol.kg-1 x min-1, not significant).	Phenylalanine	15-28	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
1466438-1	1992	The report describes a patient during induction of anaesthesia for coronary artery by-pass grafting, in whom the infusion of dobutamine at a rate of 5 micrograms.kg-1.min-1 resulted in unanticipated severe hypertension.	Dobutamine	125-135	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
1467140-3	1992	The mean plasma clearance of morphine was 20.1 ml min-1 kg-1 in neonates and 23.4 ml min-1 kg-1 in the group as a whole.	Morphine	29-37	CD59 molecule (CD59 blood group)	Homo sapiens	50-60
1467141-1	1992	Amantadine was found to be concentrated by human cortical slices, with apparent Km and Vmax values of 187 +/- 11 microM and 1.37 +/- 0.28 nmol mg-1 min-1 respectively (mean +/- s.e.	Amantadine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
1360337-5	1992	The infusion required for 95% twitch depression (TD95) for atracurium was 7.6 +/- 1.1 micrograms.kg-1 x min-1.	Atracurium	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
1360337-10	1992	The addition of an inhalation agent to atracurium reduced the infusion rate by 2.01 +/- 0.28 micrograms.kg-1 x min-1 (P = 0.0001) for each increase in MAC.	Atracurium	39-49	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
1451223-5	1992	Mean oxygen consumption during haemodynamic catheterization was 4.1 +/- 0.4 ml.kg-1 x min-1 with an average individual variation of 10%.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
1424484-4	1992	Oxygen uptake was lower in the diabetic men than in the control men both at anaerobic threshold (15.0 +/- 0.8 vs. 18.8 +/- 1.0 ml min-1 kg-1, P &lt; 0.01) and at peak exercise (25.3 +/- 1.5 vs. 31.1 +/- 1.4 ml min-1 kg-1, P &lt; 0.01).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	130-140
1424484-4	1992	Oxygen uptake was lower in the diabetic men than in the control men both at anaerobic threshold (15.0 +/- 0.8 vs. 18.8 +/- 1.0 ml min-1 kg-1, P &lt; 0.01) and at peak exercise (25.3 +/- 1.5 vs. 31.1 +/- 1.4 ml min-1 kg-1, P &lt; 0.01).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	210-220
1397716-6	1992	Basal HGO and fasting plasma glucose levels were lower (94.1 +/- 9.2 vs. 118.5 +/- 9.5 mg.m-2 x min-1, P = 0.01; and 8.3 +/- 1.2 vs. 9.8 +/- 1.2 mM; P &lt; 0.001), respectively.	Glucose	29-36	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
8359177-3	1993	In the control period, urinary dopamine excretion was 400 pg.min-1 in baseline conditions and 340 pg.min-1 during ANP infusion.	Dopamine	31-39	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
8359177-4	1993	Carbidopa significantly decreased urinary dopamine excretion both before (210 pg.min-1) and during ANP (99 pg.min-1).	Carbidopa	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
8359177-4	1993	Carbidopa significantly decreased urinary dopamine excretion both before (210 pg.min-1) and during ANP (99 pg.min-1).	Carbidopa	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
1425612-2	1992	Adrenaline was administered at five infusion rates (0.01-0.2 micrograms kg-1 min-1) in an escalating sequence to eight volunteers.	Epinephrine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
1425612-6	1992	Non-esterified fatty acids increased from 379 +/- 97 to 1114 +/- 331 mumol litre-1 during the 0.06 microgram kg-1 min-1 infusion rate.	Fatty Acids, Nonesterified	0-26	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
1389847-5	1992	The corresponding changes for DO2I (DO2 m-2) were from 643 (35) ml min-1 m-2 to 1240 (142) ml min-1 m-2 (P &lt; 0.05).	do2	30-33	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
1279272-6	1992	The possible glycophosphoinositol-type anchorage of protectin in the heart was examined by treating myocardial sections with glycophosphoinositol-specific phospholipase C. RESULTS: Immunoblotting and immunofluorescence analysis showed expression of protectin in the sarcolemmal membranes of normal myocardium.	glycophosphoinositol	13-33	CD59 molecule (CD59 blood group)	Homo sapiens	52-61
1279272-6	1992	The possible glycophosphoinositol-type anchorage of protectin in the heart was examined by treating myocardial sections with glycophosphoinositol-specific phospholipase C. RESULTS: Immunoblotting and immunofluorescence analysis showed expression of protectin in the sarcolemmal membranes of normal myocardium.	glycophosphoinositol	125-145	CD59 molecule (CD59 blood group)	Homo sapiens	52-61
1279272-9	1992	In normal myocardium the expression of CD59 was sensitive to treatment with glycophosphoinositol-specific phospholipase C. The expression of CD59 was lost or clearly diminished in infarcted lesions aged 1-14 days.	glycophosphoinositol	76-96	CD59 molecule (CD59 blood group)	Homo sapiens	39-43
1279272-9	1992	In normal myocardium the expression of CD59 was sensitive to treatment with glycophosphoinositol-specific phospholipase C. The expression of CD59 was lost or clearly diminished in infarcted lesions aged 1-14 days.	glycophosphoinositol	76-96	CD59 molecule (CD59 blood group)	Homo sapiens	141-145
1279272-12	1992	CONCLUSIONS: Glycophosphoinositol-anchored CD59 is expressed in the sarcolemmal membranes of normal heart but lost from infarcted myocardium.	glycophosphoinositol	13-33	CD59 molecule (CD59 blood group)	Homo sapiens	43-47
1425672-7	1992	The kinetic data obtained in this study indicate that 1,4-diamino-2-butyne is a mechanism-based inactivator with number of turnovers, r = 17 and characteristic constants K" = 0.32 mM and k(in) = 4.89 min-1.	1,4-diamino-2-butyne	54-74	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
1279944-6	1992	Thyroid stimulating hormone, phorbol 12, 13-dibutyrate and thyroid stimulating autoantibody enhanced the MACIF and DAF expression.	Thyrotropin	0-27	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
1279944-6	1992	Thyroid stimulating hormone, phorbol 12, 13-dibutyrate and thyroid stimulating autoantibody enhanced the MACIF and DAF expression.	Phorbol 12,13-Dibutyrate	29-54	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
1441861-9	1992	Twenty-minute flushing with oxygen (8 l min-1) decreased effluent gas concentrations below 5 p.p.m.	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
1449039-6	1992	Total glucose uptake was impaired in the insulin-resistant subjects with impaired first-phase insulin secretion compared to controls (18.8 (13.2-22.2) vs 34.8 (24.3-62.1) mumol.kg-1 x min-1; p &lt; 0.01).	Glucose	6-13	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
1457266-4	1992	rate (nmol min-1 mg-1 protein) of histamine N-methylation was 1.78 +/- 0.59 (liver, n = 60), 1.15 +/- 0.38 (renal cortex, n = 8), 0.79 +/- 0.14 (renal medulla, n = 8), 0.35 +/- 0.08 (lung, n = 20), 0.47 +/- 0.18 (human intestine, n = 30) and 0.29 +/- 0.14 (brain, n = 13).	histamine n	34-45	CD59 molecule (CD59 blood group)	Homo sapiens	11-21
1457268-13	1992	192C86 (0.007-0.058 micrograms kg-1 min-1) inhibited platelet aggregation to ADP and collagen both in PRP and WB in a dose-dependent manner.	Adenosine Diphosphate	77-80	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
1327925-3	1992	Na+/H+ antiport activity (measured as the rate of amiloride-sensitive Na+ influx at pHi = 6.4, extracellular pH = 8.0, and [Na+] = 1 mM) was elevated significantly in IDDM patients with nephropathy compared with IDDM patients without nephropathy and nondiabetic control subjects (13.35 +/- 3.8 vs. 8.54 +/- 2.0 vs. 7.33 +/- 2.3 nmol Na+.mg protein-1.min-1; P less than 0.006 and P less than 0.001, respectively).	Amiloride	50-59	CD59 molecule (CD59 blood group)	Homo sapiens	350-355
1382093-1	1992	A significant fraction of human glycosyl-phosphatidylinositol-anchored Ag CD59, CD55, CD48, and CDw52 is present in several cell lines tested (HPB-ALL, Jurkat, HL-60, Raji) in very large noncovalent complexes relatively resistant to dissociation by detergents.	Glycosylphosphatidylinositols	32-61	CD59 molecule (CD59 blood group)	Homo sapiens	74-78
1453491-2	1992	All cell types exhibited high affinity uptake of malate (Km 10-85 microM) with slightly higher Vmax values in neurons (0.1-0.2 nmol x min-1 x mg-1) than in astrocytes (0.06 nmol x min-1 x mg-1).	malic acid	49-55	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
1453491-2	1992	All cell types exhibited high affinity uptake of malate (Km 10-85 microM) with slightly higher Vmax values in neurons (0.1-0.2 nmol x min-1 x mg-1) than in astrocytes (0.06 nmol x min-1 x mg-1).	malic acid	49-55	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
1453491-3	1992	Malate was oxidatively metabolized in all three cell types with nominal rates of 14CO2 production of 2-15 pmol x min-1 x mg-1.	malic acid	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
1453491-3	1992	Malate was oxidatively metabolized in all three cell types with nominal rates of 14CO2 production of 2-15 pmol x min-1 x mg-1.	14co2	81-86	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
1338493-3	1992	The analyte is detected by UV absorption at 300 nm after post-column derivatization with acidic iron(III) solution (0.25 ml min-1).	ferric sulfate	96-105	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
1435164-5	1992	For a given VO2, heart rate was 8-11 beats.min-1 lower during water running than during treadmill running, irrespective of exercise intensity.	Water	62-67	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
1381035-5	1992	Conversely, blockade of CD59 with monoclonal antibody increased complement-mediated oxygen radical production and release of prostaglandin E2, interleukin-1 alpha, and interleukin-6.	Reactive Oxygen Species	84-98	CD59 molecule (CD59 blood group)	Homo sapiens	24-28
1381035-5	1992	Conversely, blockade of CD59 with monoclonal antibody increased complement-mediated oxygen radical production and release of prostaglandin E2, interleukin-1 alpha, and interleukin-6.	Dinoprostone	125-141	CD59 molecule (CD59 blood group)	Homo sapiens	24-28
1394617-2	1992	The second order rate constants for the reaction of ebselen (0.29 mM-1 min-1), ebselen-glutathione selenosulfide (less than or equal to 0.01 mM-1 min-1), ebselen selenol (2.8 mM-1 min-1) and ebselen diselenide (0.32 mM-1 min-1) with hydrogen peroxide reveal that the selenol is particularly active in this respect.	ebselen	52-59	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
1394617-2	1992	The second order rate constants for the reaction of ebselen (0.29 mM-1 min-1), ebselen-glutathione selenosulfide (less than or equal to 0.01 mM-1 min-1), ebselen selenol (2.8 mM-1 min-1) and ebselen diselenide (0.32 mM-1 min-1) with hydrogen peroxide reveal that the selenol is particularly active in this respect.	ebselen	52-59	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
1394617-2	1992	The second order rate constants for the reaction of ebselen (0.29 mM-1 min-1), ebselen-glutathione selenosulfide (less than or equal to 0.01 mM-1 min-1), ebselen selenol (2.8 mM-1 min-1) and ebselen diselenide (0.32 mM-1 min-1) with hydrogen peroxide reveal that the selenol is particularly active in this respect.	ebselen	52-59	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
1394617-2	1992	The second order rate constants for the reaction of ebselen (0.29 mM-1 min-1), ebselen-glutathione selenosulfide (less than or equal to 0.01 mM-1 min-1), ebselen selenol (2.8 mM-1 min-1) and ebselen diselenide (0.32 mM-1 min-1) with hydrogen peroxide reveal that the selenol is particularly active in this respect.	ebselen	52-59	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
1394617-2	1992	The second order rate constants for the reaction of ebselen (0.29 mM-1 min-1), ebselen-glutathione selenosulfide (less than or equal to 0.01 mM-1 min-1), ebselen selenol (2.8 mM-1 min-1) and ebselen diselenide (0.32 mM-1 min-1) with hydrogen peroxide reveal that the selenol is particularly active in this respect.	ebselen-glutathione selenosulfide	79-112	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
1394617-2	1992	The second order rate constants for the reaction of ebselen (0.29 mM-1 min-1), ebselen-glutathione selenosulfide (less than or equal to 0.01 mM-1 min-1), ebselen selenol (2.8 mM-1 min-1) and ebselen diselenide (0.32 mM-1 min-1) with hydrogen peroxide reveal that the selenol is particularly active in this respect.	ebselen-glutathione selenosulfide	79-112	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
1394617-2	1992	The second order rate constants for the reaction of ebselen (0.29 mM-1 min-1), ebselen-glutathione selenosulfide (less than or equal to 0.01 mM-1 min-1), ebselen selenol (2.8 mM-1 min-1) and ebselen diselenide (0.32 mM-1 min-1) with hydrogen peroxide reveal that the selenol is particularly active in this respect.	ebselen-glutathione selenosulfide	79-112	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
1423468-6	1992	The standard error of the mean of the maximal oxygen consumption estimate from the 2000 m walk is 3.44 ml.kg-1 x min-1 (5.7%) and from the running time of the same distance 3.49 ml.kg-1 x min-1 (5.8%).	Oxygen	46-52	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
1423468-6	1992	The standard error of the mean of the maximal oxygen consumption estimate from the 2000 m walk is 3.44 ml.kg-1 x min-1 (5.7%) and from the running time of the same distance 3.49 ml.kg-1 x min-1 (5.8%).	Oxygen	46-52	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
1325107-3	1992	After a left main intracoronary infusion of dobutamine (25 to 200 micrograms.min-1), beta-adrenergic contractile responsiveness was assessed as the net increase in peak positive LV dp/dt (delta LV dp/dt).	Dobutamine	44-54	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
1389847-5	1992	The corresponding changes for DO2I (DO2 m-2) were from 643 (35) ml min-1 m-2 to 1240 (142) ml min-1 m-2 (P &lt; 0.05).	do2	30-33	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
1325260-3	1992	The most demanding firefighting operations required a mean VO2 of 41.5 ml/kg.min-1 with peak lactate concentrations of 6 to 13.2 mM.	Lactic Acid	93-100	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
1396624-2	1992	The mean doses including induction were 0.75 +/- 0.31 mg kg-1 h-1 for midazolam and 171 +/- 64 micrograms kg-1 min-1 for propofol for 46.3 +/- 17.7 min and 50.3 +/- 24.8 min respectively.	Propofol	121-129	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
1484352-9	1992	Following induction of inspiratory muscle fatigue, the slope of the ventilatory response to CO2 was significantly decreased from 18.8 +/- 3.3 during control to 13.8 +/- 2.1 l min-1 (% end-tidal CO2 concentration)-1 with fatigue (P &lt; 0.02).	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	92-95	CD59 molecule (CD59 blood group)	Homo sapiens	175-180
1389847-2	1992	Nine healthy, adult, non-obese, male physicians were infused with an incremental infusion of dobutamine starting at 2.5 micrograms kg-1 min-1 increasing to 5.0 and then 7.5 micrograms kg-1 min-1 for 15 min each.	Dobutamine	93-103	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
1389847-5	1992	The corresponding changes for DO2I (DO2 m-2) were from 643 (35) ml min-1 m-2 to 1240 (142) ml min-1 m-2 (P &lt; 0.05).	do2i	30-34	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
1389847-5	1992	The corresponding changes for DO2I (DO2 m-2) were from 643 (35) ml min-1 m-2 to 1240 (142) ml min-1 m-2 (P &lt; 0.05).	do2i	30-34	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
1433876-6	1992	A significant attenuation in heart rate response to intravenous atropine 10 micrograms.kg-1 was observed in patients receiving clonidine 5 micrograms.kg-1, as compared with that in the control group (P less than 0.01); maximal increases in heart rate were 15 +/- 8 and 22 +/- 6 beats.min-1 (mean +/- SD) in the clonidine and control groups, respectively.	Atropine	64-72	CD59 molecule (CD59 blood group)	Homo sapiens	284-289
1433876-6	1992	A significant attenuation in heart rate response to intravenous atropine 10 micrograms.kg-1 was observed in patients receiving clonidine 5 micrograms.kg-1, as compared with that in the control group (P less than 0.01); maximal increases in heart rate were 15 +/- 8 and 22 +/- 6 beats.min-1 (mean +/- SD) in the clonidine and control groups, respectively.	Clonidine	127-136	CD59 molecule (CD59 blood group)	Homo sapiens	284-289
1361068-7	1992	Salmeterol 100 micrograms twice daily was consistently superior to salmeterol 50 micrograms twice daily in morning and evening PEFR measurements (mean differences between the treatments: 10-14 l min-1 for morning, 95% CI-0, 22 l min-1, P = 0.047; and 10-15 l min-1 for evening, 95% CI 2, 22 l min-1, P = 0.023).	Salmeterol Xinafoate	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	195-200
1361068-7	1992	Salmeterol 100 micrograms twice daily was consistently superior to salmeterol 50 micrograms twice daily in morning and evening PEFR measurements (mean differences between the treatments: 10-14 l min-1 for morning, 95% CI-0, 22 l min-1, P = 0.047; and 10-15 l min-1 for evening, 95% CI 2, 22 l min-1, P = 0.023).	Salmeterol Xinafoate	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	229-234
1361068-7	1992	Salmeterol 100 micrograms twice daily was consistently superior to salmeterol 50 micrograms twice daily in morning and evening PEFR measurements (mean differences between the treatments: 10-14 l min-1 for morning, 95% CI-0, 22 l min-1, P = 0.047; and 10-15 l min-1 for evening, 95% CI 2, 22 l min-1, P = 0.023).	Salmeterol Xinafoate	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	229-234
1361068-7	1992	Salmeterol 100 micrograms twice daily was consistently superior to salmeterol 50 micrograms twice daily in morning and evening PEFR measurements (mean differences between the treatments: 10-14 l min-1 for morning, 95% CI-0, 22 l min-1, P = 0.047; and 10-15 l min-1 for evening, 95% CI 2, 22 l min-1, P = 0.023).	Salmeterol Xinafoate	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	229-234
1519724-4	1992	Oxygen, 4 l.min-1, was administrated by paediatric face mask.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	12-17
1514350-1	1992	Adenosine, an endogenous compound with a known antinociceptive effect when administered into the CNS, was applied in nine patients (21-65 years) by the peripheral intravenous route (70-130 micrograms.kg-1.min-1) as a replacement for peroperative opioids during inhalation anaesthesia for surgical procedures not requiring muscle relaxation.	Adenosine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
1389825-10	1992	Oxygen by mask at 4 litre min-1 maintained an average saturation &gt; or = 95% in most, but not all, of the patients.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	26-31
1503923-5	1992	Median methotrexate clearance tended to be lower in four infants (0.26-0.99 years) vs 108 children (1-19 years): 80 vs 103 ml min-1 m-2, respectively (P = 0.01).	Methotrexate	7-19	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
1366257-11	1992	The ACE activity in serum 24 h post-dose was lower (p &lt; 0.001) after treatment with lisinopril 8.0 (SD 3.3) mumol/min/1 than with enalapril 16.1 (SD 6.0).	Lisinopril	87-97	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
1451157-3	1992	METHODS: Increasing doses of adenosine were given to seven male patients with ischaemic heart disease referred for coronary angiography: first as a bolus intracoronary injection (2.5-50 mumol), second as a 1 ml.min-1 steady state infusion (0.01-20 mumol.min-1) and third as an intravenous steady state infusion (0.076-0.76 mumol.kg-1 x min-1).	Adenosine	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
1451157-3	1992	METHODS: Increasing doses of adenosine were given to seven male patients with ischaemic heart disease referred for coronary angiography: first as a bolus intracoronary injection (2.5-50 mumol), second as a 1 ml.min-1 steady state infusion (0.01-20 mumol.min-1) and third as an intravenous steady state infusion (0.076-0.76 mumol.kg-1 x min-1).	Adenosine	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	254-259
1451157-3	1992	METHODS: Increasing doses of adenosine were given to seven male patients with ischaemic heart disease referred for coronary angiography: first as a bolus intracoronary injection (2.5-50 mumol), second as a 1 ml.min-1 steady state infusion (0.01-20 mumol.min-1) and third as an intravenous steady state infusion (0.076-0.76 mumol.kg-1 x min-1).	Adenosine	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	254-259
1425863-5	1992	Dopamine increased baseline GFR from 89 +/- 3 (mean +/- SEM, n = 8) to 102 +/- 4 ml min-1 1.73 m-2 and ERPF from 352 +/- 19 to 476 +/- 26 ml min-1 1.73 m-2, P less than 0.001 for both.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
1425863-5	1992	Dopamine increased baseline GFR from 89 +/- 3 (mean +/- SEM, n = 8) to 102 +/- 4 ml min-1 1.73 m-2 and ERPF from 352 +/- 19 to 476 +/- 26 ml min-1 1.73 m-2, P less than 0.001 for both.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
1425863-7	1992	Octreotide did not significantly decrease baseline and dopamine-stimulated renal haemodynamics but lowered the amino acid-stimulated GFR (98 +/- 4 ml min-1 1.73 m-2, P less than 0.05) and ERPF (381 +/- 18 ml min-1 1.73 m-2, P less than 0.05).	Octreotide	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
1425863-7	1992	Octreotide did not significantly decrease baseline and dopamine-stimulated renal haemodynamics but lowered the amino acid-stimulated GFR (98 +/- 4 ml min-1 1.73 m-2, P less than 0.05) and ERPF (381 +/- 18 ml min-1 1.73 m-2, P less than 0.05).	Octreotide	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
1505562-6	1992	Lidocaine did not change cardiac output during ventricular tachycardia whereas cardiac output increased significantly under ajmaline from 3.5 +/- 1.21.min-1 to 5.5 +/- 1.91.min-1 (P less than 0.001).	Ajmaline	124-132	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
1505562-6	1992	Lidocaine did not change cardiac output during ventricular tachycardia whereas cardiac output increased significantly under ajmaline from 3.5 +/- 1.21.min-1 to 5.5 +/- 1.91.min-1 (P less than 0.001).	Ajmaline	124-132	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
1383132-4	1992	CD59 Ag on HAEC is similar in size to the erythrocyte protein and is anchored via glycosyl phosphatidylinositol.	Glycosylphosphatidylinositols	82-111	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
1412117-4	1992	RESULTS: In both groups of subjects the average values of FIO2 with nasal cannulas at 1 and 2 l min-1 were of a similar order to those achieved with 24.5% and 28% Venturi masks, but variations within and between subjects in both groups breathing via nasal cannulas were considerable and similar to those found with MC masks.	fio2	58-62	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
1440521-1	1992	Under conditions closely approximating those in vivo (100 mM sodium carbonate pH 7.3 with 0.9% NaCl, 37 degrees C), antithrombin III (AT III) and the C1 inhibitor (C1-INH) are inactivated by methylglyoxal (MG) with pseudofirst-order kinetics and second-order rate constants of 25.2 and 7.8 M-1 min-1, respectively.	Pyruvaldehyde	191-204	CD59 molecule (CD59 blood group)	Homo sapiens	294-299
1514686-4	1992	The assay uses a thioester derivative of diheptanoyl phosphatidylcholine as a substrate, with which the enzyme displays a specific activity of about 25 mumol min-1 mg-1.	Cy5-benzyl thioester	17-26	CD59 molecule (CD59 blood group)	Homo sapiens	158-168
1514686-4	1992	The assay uses a thioester derivative of diheptanoyl phosphatidylcholine as a substrate, with which the enzyme displays a specific activity of about 25 mumol min-1 mg-1.	diheptanoyl phosphatidylcholine	41-72	CD59 molecule (CD59 blood group)	Homo sapiens	158-168
1616160-4	1992	The average alfentanil dosage requirements were 1.49 +/- 0.50 and 1.46 +/- 0.55 micrograms.kg-1.min-1 (mean +/- SD) in the physician- and patient-controlled groups, respectively.	Alfentanil	12-22	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
1505161-5	1992	Peak O2 consumption of the patients was 14.9 +/- 5.3 ml min-1 kg-1 and that of controls 33.6 +/- 7.5 ml min-1 kg-1.	Oxygen	5-7	CD59 molecule (CD59 blood group)	Homo sapiens	56-66
1321046-8	1992	Kinetic analysis in the presence of Mn2+ gave an apparent Vmax value of 20 nmol min-1 mg-1 and Km values of 4.5 microM for ATP and 1.43 mM for angiotensin II.	Manganese(2+)	36-40	CD59 molecule (CD59 blood group)	Homo sapiens	80-90
1321046-8	1992	Kinetic analysis in the presence of Mn2+ gave an apparent Vmax value of 20 nmol min-1 mg-1 and Km values of 4.5 microM for ATP and 1.43 mM for angiotensin II.	Adenosine Triphosphate	123-126	CD59 molecule (CD59 blood group)	Homo sapiens	80-90
1321046-11	1992	The specific activity of the intracellular domain of the EGF-R, when assayed at 20 degrees C in the presence of 1M ammonium sulfate, was 160 nmol min-1 mg-1.	Ammonium Sulfate	115-131	CD59 molecule (CD59 blood group)	Homo sapiens	146-156
1378022-11	1992	The CR2+ Ramos and the CR2- Rael cells were treated with 5-azacytidine which induced HRF20 and increased DAF expression.	Azacitidine	57-70	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
1378024-2	1992	The cDNA of HRF20 was transfected into Chinese hamster ovary (CHO) cells resulting in expression of human HRF20 protein on the cell surface anchored via glycosylphosphatidyl inositol.	Glycosylphosphatidylinositols	153-182	CD59 molecule (CD59 blood group)	Homo sapiens	12-17
1378024-2	1992	The cDNA of HRF20 was transfected into Chinese hamster ovary (CHO) cells resulting in expression of human HRF20 protein on the cell surface anchored via glycosylphosphatidyl inositol.	Glycosylphosphatidylinositols	153-182	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
1495189-5	1992	Diltiazem was administered i. v. at a rate of 3 micrograms.kg-1.min-1 before induction of anesthesia.	Diltiazem	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
1495189-9	1992	Hypertension during the manipulation of the tumor was controlled by increasing the inspired concentration of enflurane or by increasing the infusion rate of diltiazem to 5 micrograms.kg-1.min-1.	Diltiazem	157-166	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
1610797-3	1992	At 2-5 microM secosteroid, the dehydrogenase activity is alkylated in a site-specific manner (pregnenolone slows inactivation) that follows first-order inactivation kinetics (KI = 4.2 microM, k3 = 1.31 x 10(-2) min-1).	Secosteroids	14-25	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
1610797-3	1992	At 2-5 microM secosteroid, the dehydrogenase activity is alkylated in a site-specific manner (pregnenolone slows inactivation) that follows first-order inactivation kinetics (KI = 4.2 microM, k3 = 1.31 x 10(-2) min-1).	Pregnenolone	94-106	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
1596009-5	1992	Oxygen consumption and delivery both increased significantly at 3 h (219 +/- 17 and 1,030 +/- 43 ml/min.min2) and 5 h (203 +/- 7 and 949 +/- 48 ml/min.min2) (p less than or equal to 0.035), whereas oxygen extraction fell at 3 h (p = 0.041).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	104-108
1596009-5	1992	Oxygen consumption and delivery both increased significantly at 3 h (219 +/- 17 and 1,030 +/- 43 ml/min.min2) and 5 h (203 +/- 7 and 949 +/- 48 ml/min.min2) (p less than or equal to 0.035), whereas oxygen extraction fell at 3 h (p = 0.041).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	151-155
1596009-5	1992	Oxygen consumption and delivery both increased significantly at 3 h (219 +/- 17 and 1,030 +/- 43 ml/min.min2) and 5 h (203 +/- 7 and 949 +/- 48 ml/min.min2) (p less than or equal to 0.035), whereas oxygen extraction fell at 3 h (p = 0.041).	Oxygen	198-204	CD59 molecule (CD59 blood group)	Homo sapiens	151-155
1621876-2	1992	Infusion of approximately 3 ng.kg-1.min-1 glucagon or approximately 2 ng.kg-1.min-1 CCK-8 each reduced test meal size.	Glucagon	42-50	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
1534646-11	1992	In group LP, mean HR increased less than in group SP (56 +/- 8 to 62 +/- 14 beats.min-1), whereas MAP and CI declined significantly.	leucylproline	9-11	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
1595920-9	1992	In four additional patients receiving smaller consecutive infusions of propofol (50 and 100 micrograms.kg-1.min-1), significant subtle increases in forearm compliance were also recorded.	Propofol	71-79	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
1389934-12	1992	The mean renal clearance of oxycodone was 0.07-0.08 l min-1.	Oxycodone	28-37	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
1587401-4	1992	Tests were preceded by identical fasts of 10-12 h. In nonobese subjects, glucose tolerance, expressed as the 10- to 16-min KG value (KGs), was much reduced in the evening (AM 2.98 +/- 0.45, PM 1.86 +/- 0.33 min-1, P less than 0.002).	Glucose	73-80	CD59 molecule (CD59 blood group)	Homo sapiens	207-212
1587401-6	1992	The reduction in glucose tolerance in the normal-weight subjects was caused by diminished insulin sensitivity (parameter S1, AM 15.4 +/- 2.9, PM 10.2 +/- 1.9 x 10(-5) min-1/pM, P less than 0.01) and reduced beta-cell responsivity to glucose.	Glucose	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
1612297-4	1992	The activity in unstimulated PMNs was 0.64 +/- 0.11 nmol of PA hydrolyzed.mg protein-1.min-1 in particulate and 4.20 +/- 0.42 in soluble fractions.	Protactinium	60-62	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
1316878-7	1992	Formation of NADP+ was 20.3 +/- 1.8 nmol min-1 for pyocyanin (10 microM) at pH 5.5, compared with 0.6 +/- 0.2 nmol min-1 for 1-OHP (10 microM), while at pH 7.5 a value of 2.2 +/- 1.3 nmol min-1 was obtained for pyocyanin, with no detectable activity for 1-OHP.	NADP	13-18	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
1316878-7	1992	Formation of NADP+ was 20.3 +/- 1.8 nmol min-1 for pyocyanin (10 microM) at pH 5.5, compared with 0.6 +/- 0.2 nmol min-1 for 1-OHP (10 microM), while at pH 7.5 a value of 2.2 +/- 1.3 nmol min-1 was obtained for pyocyanin, with no detectable activity for 1-OHP.	NADP	13-18	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
1316878-7	1992	Formation of NADP+ was 20.3 +/- 1.8 nmol min-1 for pyocyanin (10 microM) at pH 5.5, compared with 0.6 +/- 0.2 nmol min-1 for 1-OHP (10 microM), while at pH 7.5 a value of 2.2 +/- 1.3 nmol min-1 was obtained for pyocyanin, with no detectable activity for 1-OHP.	NADP	13-18	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
1316878-7	1992	Formation of NADP+ was 20.3 +/- 1.8 nmol min-1 for pyocyanin (10 microM) at pH 5.5, compared with 0.6 +/- 0.2 nmol min-1 for 1-OHP (10 microM), while at pH 7.5 a value of 2.2 +/- 1.3 nmol min-1 was obtained for pyocyanin, with no detectable activity for 1-OHP.	Pyocyanine	51-60	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
1316878-7	1992	Formation of NADP+ was 20.3 +/- 1.8 nmol min-1 for pyocyanin (10 microM) at pH 5.5, compared with 0.6 +/- 0.2 nmol min-1 for 1-OHP (10 microM), while at pH 7.5 a value of 2.2 +/- 1.3 nmol min-1 was obtained for pyocyanin, with no detectable activity for 1-OHP.	Oxaliplatin	125-130	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
1316878-7	1992	Formation of NADP+ was 20.3 +/- 1.8 nmol min-1 for pyocyanin (10 microM) at pH 5.5, compared with 0.6 +/- 0.2 nmol min-1 for 1-OHP (10 microM), while at pH 7.5 a value of 2.2 +/- 1.3 nmol min-1 was obtained for pyocyanin, with no detectable activity for 1-OHP.	Oxaliplatin	125-130	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
1434581-4	1992	Significant increases (p less than 0.001) in maximal oxygen uptake occurred in both the aerobics (+3.9 ml/kg-1/min-1) and walk-jog group (+3.4 ml/kg-1/min-1), while no significant change was observed in the control group.	Oxygen	53-59	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
1434581-4	1992	Significant increases (p less than 0.001) in maximal oxygen uptake occurred in both the aerobics (+3.9 ml/kg-1/min-1) and walk-jog group (+3.4 ml/kg-1/min-1), while no significant change was observed in the control group.	Oxygen	53-59	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
1412379-5	1992	There is a significant increase in coronary bypass flow induced by both rates of 0.4 and 0.8 microgram x kg-1 x min-1 dobutamine, but there was no significant effect on bypass flow induced by dopamine.	Dobutamine	118-128	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
1412379-8	1992	A significant increase in rate of contraction and relaxation was only induced by the higher dosage of 0.8 microgram x kg-1 x min-1 dobutamine.	Dobutamine	131-141	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
1534467-3	1992	The mean enflurane uptake rates were between 24 and 14 ml.70kg-1.min-1 between 10 and 60 minutes.	Enflurane	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
1642937-3	1992	The median propofol total body clearance, derived from the apparent steady state propofol blood concentrations during infusion, was 2.11 litre min-1.	Propofol	11-19	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
1642938-2	1992	When the first EMG response (T1) of the train-of-four had recovered to 5% of control (T0), an infusion of mivacurium 10 micrograms kg-1 min-1 was started and adjusted to keep T1 at 5%.	Mivacurium	106-116	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
1535589-6	1992	Following amiodarone therapy there was a significant reduction in resting and peak heart rate during erect exercise (76 +/- 13 vs 97 +/- 19 b.min-1; P = 0.001 and 114 +/- 26 vs 146 +/- 21 b.min-1; P = 0.001 respectively).	Amiodarone	10-20	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
1535589-6	1992	Following amiodarone therapy there was a significant reduction in resting and peak heart rate during erect exercise (76 +/- 13 vs 97 +/- 19 b.min-1; P = 0.001 and 114 +/- 26 vs 146 +/- 21 b.min-1; P = 0.001 respectively).	Amiodarone	10-20	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
1572354-7	1992	The expression of lactate dehydrogenase activity in the low-water system was higher with the heart than with the muscle enzyme compared to their activities in all-water media (about 260 and 600 mumol min-1 mg-1 in the heart and muscle enzymes respectively).	Water	60-65	CD59 molecule (CD59 blood group)	Homo sapiens	200-210
1607083-6	1992	Supplemental oxygen given at a rate of 2 liters.min-1 was as effective as that given at a rate of 3 liters.min-1 in preventing significant desaturation, as previously defined, during the procedure.	Oxygen	13-19	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
1607083-6	1992	Supplemental oxygen given at a rate of 2 liters.min-1 was as effective as that given at a rate of 3 liters.min-1 in preventing significant desaturation, as previously defined, during the procedure.	Oxygen	13-19	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
1406613-4	1992	The rate constant of the reaction of nitrogen mustard with guanine in the polynucleotide (k = 9,0.10(-3) min-1) is about one-third of that for the fixation of Z-form of the (dG-dC)-insert in the plasmid (k1 = 2,8.10(-2) min-1) which is attributed to a greater rate of formation of diguanyl derivative in the opposite DNA chains.	Nitrogen	37-45	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
1406613-4	1992	The rate constant of the reaction of nitrogen mustard with guanine in the polynucleotide (k = 9,0.10(-3) min-1) is about one-third of that for the fixation of Z-form of the (dG-dC)-insert in the plasmid (k1 = 2,8.10(-2) min-1) which is attributed to a greater rate of formation of diguanyl derivative in the opposite DNA chains.	Nitrogen	37-45	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
1406613-4	1992	The rate constant of the reaction of nitrogen mustard with guanine in the polynucleotide (k = 9,0.10(-3) min-1) is about one-third of that for the fixation of Z-form of the (dG-dC)-insert in the plasmid (k1 = 2,8.10(-2) min-1) which is attributed to a greater rate of formation of diguanyl derivative in the opposite DNA chains.	Guanine	59-66	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
1406613-4	1992	The rate constant of the reaction of nitrogen mustard with guanine in the polynucleotide (k = 9,0.10(-3) min-1) is about one-third of that for the fixation of Z-form of the (dG-dC)-insert in the plasmid (k1 = 2,8.10(-2) min-1) which is attributed to a greater rate of formation of diguanyl derivative in the opposite DNA chains.	Guanine	59-66	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
1406613-4	1992	The rate constant of the reaction of nitrogen mustard with guanine in the polynucleotide (k = 9,0.10(-3) min-1) is about one-third of that for the fixation of Z-form of the (dG-dC)-insert in the plasmid (k1 = 2,8.10(-2) min-1) which is attributed to a greater rate of formation of diguanyl derivative in the opposite DNA chains.	Polynucleotides	74-88	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
1406613-4	1992	The rate constant of the reaction of nitrogen mustard with guanine in the polynucleotide (k = 9,0.10(-3) min-1) is about one-third of that for the fixation of Z-form of the (dG-dC)-insert in the plasmid (k1 = 2,8.10(-2) min-1) which is attributed to a greater rate of formation of diguanyl derivative in the opposite DNA chains.	Polynucleotides	74-88	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
1406613-4	1992	The rate constant of the reaction of nitrogen mustard with guanine in the polynucleotide (k = 9,0.10(-3) min-1) is about one-third of that for the fixation of Z-form of the (dG-dC)-insert in the plasmid (k1 = 2,8.10(-2) min-1) which is attributed to a greater rate of formation of diguanyl derivative in the opposite DNA chains.	Proguanil	281-289	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
1373727-0	1992	Contribution of the N-linked carbohydrate of erythrocyte antigen CD59 to its complement-inhibitory activity.	n-linked carbohydrate	20-41	CD59 molecule (CD59 blood group)	Homo sapiens	65-69
1312812-5	1992	As determined with leukotriene C4 synthase of a crude membrane fraction from human platelets, the Km value was 7 microM and the V value was 0.56 nmol x min-1 x mg-1 with leukotriene A4 as substrate.	Leukotriene A4	170-184	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
1316068-1	1992	The quinolone antibiotic lomefloxacin was administered as a 400 mg single oral dose to 12 subjects with renal impairment (creatinine clearance 5-65 mL/min/1.73 m2) and to 13 healthy subjects (creatinine clearance 80-135 mL/min/1.73 m2).	Quinolones	4-13	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
1316068-1	1992	The quinolone antibiotic lomefloxacin was administered as a 400 mg single oral dose to 12 subjects with renal impairment (creatinine clearance 5-65 mL/min/1.73 m2) and to 13 healthy subjects (creatinine clearance 80-135 mL/min/1.73 m2).	lomefloxacin	25-37	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
1316068-1	1992	The quinolone antibiotic lomefloxacin was administered as a 400 mg single oral dose to 12 subjects with renal impairment (creatinine clearance 5-65 mL/min/1.73 m2) and to 13 healthy subjects (creatinine clearance 80-135 mL/min/1.73 m2).	lomefloxacin	25-37	CD59 molecule (CD59 blood group)	Homo sapiens	223-228
1316068-4	1992	The mean nonrenal clearance of lomefloxacin (approximately 32 mL/min/1.72 m2) was not influenced by renal function.	lomefloxacin	31-43	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
1316068-5	1992	The mean plasma clearances of lomefloxacin in healthy subjects and in a subgroup of patients with severe renal impairment (creatinine clearance 5-15 mL/min/1.73 m2) were 209 and 43 mL/min/1.73 m2, respectively.	lomefloxacin	30-42	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
1316068-5	1992	The mean plasma clearances of lomefloxacin in healthy subjects and in a subgroup of patients with severe renal impairment (creatinine clearance 5-15 mL/min/1.73 m2) were 209 and 43 mL/min/1.73 m2, respectively.	lomefloxacin	30-42	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
1316068-9	1992	The pharmacokinetics of lomefloxacin are dependent on renal function, and appropriate dosage adjustment is necessary when creatinine clearance is less than 30 mL/min/1.73 m2.	lomefloxacin	24-36	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
1499640-3	1992	Mean fasting hepatic glucose production was 14.2 +/- 0.8 mumol kg-1 min-1.	Glucose	21-28	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
1576070-10	1992	Reducing the inspiratory flow to approximately 34 l min-1 produced slightly reduced side effects and lower plasma terbutaline concentrations.	Terbutaline	114-125	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
1607071-3	1992	Whole-body glycerol production was twofold greater in the obese children (311 vs. 156 mumol.min-1, P less than 0.01) and correlated with body fat (r = 0.67, P less than 0.005).	Glycerol	11-19	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
1607071-4	1992	Normalization of glycerol flux to fat mass revealed that the rate of triglyceride hydrolysis was in fact lower in the adipose tissue of obese children (9.4 vs. 17.7 mumol.min-1/kg body fat) and correlated with plasma insulin (r = 0.64, P less than 0.005).	Triglycerides	69-81	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
1607071-6	1992	As a direct consequence (r = 0.67, P less than 0.025) of their elevated plasma glycerol concentration (65 +/- 4 vs. 37 +/- 2 microM, P less than 0.05) obese children had an increased glycerol utilization by the whole body, as well as per unit of lean body mass (9.1 +/- 1 vs. 6.5 +/- 0.9 mumoles.min-1.kg lean body mass-1, P less than 0.025).	Glycerol	183-191	CD59 molecule (CD59 blood group)	Homo sapiens	296-301
1537826-5	1992	The best substrate for aldose reductase is methylglyoxal (kcat = 142 min-1, kcat/Km = 1.8 x 10(7) M-1 min-1), a toxic 2-oxo-aldehyde that is produced nonenzymatically from triose phosphates and enzymatically from acetone/acetol metabolism.	2-oxo-aldehyde	118-132	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
1380602-4	1992	Phenoxybenzamine increased forearm blood flow at rest (11.5 +/- 1.0 vs. 3.9 +/- 0.3 ml x 100 ml-1 x min-1; p less than 0.001).	Phenoxybenzamine	0-16	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
1522509-5	1992	NOLA (30 mg kg-1 bolus followed by 1 mg kg-1 min-1 infusion) caused an approximately 40 mmHg elevation in the mean arterial blood pressure, a regionally heterogenous increase of the regional cerebrovascular resistance and a decrease in the regional cerebral blood flow 15 and 40 min after the start of its administration.	Nitroarginine	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
1537826-5	1992	The best substrate for aldose reductase is methylglyoxal (kcat = 142 min-1, kcat/Km = 1.8 x 10(7) M-1 min-1), a toxic 2-oxo-aldehyde that is produced nonenzymatically from triose phosphates and enzymatically from acetone/acetol metabolism.	2-oxo-aldehyde	118-132	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
1537826-5	1992	The best substrate for aldose reductase is methylglyoxal (kcat = 142 min-1, kcat/Km = 1.8 x 10(7) M-1 min-1), a toxic 2-oxo-aldehyde that is produced nonenzymatically from triose phosphates and enzymatically from acetone/acetol metabolism.	triose phosphates	172-189	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
1537826-5	1992	The best substrate for aldose reductase is methylglyoxal (kcat = 142 min-1, kcat/Km = 1.8 x 10(7) M-1 min-1), a toxic 2-oxo-aldehyde that is produced nonenzymatically from triose phosphates and enzymatically from acetone/acetol metabolism.	triose phosphates	172-189	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
1537826-5	1992	The best substrate for aldose reductase is methylglyoxal (kcat = 142 min-1, kcat/Km = 1.8 x 10(7) M-1 min-1), a toxic 2-oxo-aldehyde that is produced nonenzymatically from triose phosphates and enzymatically from acetone/acetol metabolism.	Acetone	213-220	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
1537826-5	1992	The best substrate for aldose reductase is methylglyoxal (kcat = 142 min-1, kcat/Km = 1.8 x 10(7) M-1 min-1), a toxic 2-oxo-aldehyde that is produced nonenzymatically from triose phosphates and enzymatically from acetone/acetol metabolism.	Acetone	213-220	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
1537826-5	1992	The best substrate for aldose reductase is methylglyoxal (kcat = 142 min-1, kcat/Km = 1.8 x 10(7) M-1 min-1), a toxic 2-oxo-aldehyde that is produced nonenzymatically from triose phosphates and enzymatically from acetone/acetol metabolism.	acetol	221-227	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
1537826-5	1992	The best substrate for aldose reductase is methylglyoxal (kcat = 142 min-1, kcat/Km = 1.8 x 10(7) M-1 min-1), a toxic 2-oxo-aldehyde that is produced nonenzymatically from triose phosphates and enzymatically from acetone/acetol metabolism.	acetol	221-227	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
1554953-10	1992	Total clearance of cefotaxime was 62 and 79 mL/min/1.73 m2.	Cefotaxime	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
1547050-3	1992	Arterial hypotension was induced with PGE1 0.1 micrograms kg-1 min-1 initially and adjusted to maintain mean arterial pressure at about 70 mm Hg.	Alprostadil	38-42	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
1372164-6	1992	Platelet CD59 antigen is anchored to the membrane via a glycosyl-phosphatidylinositol link, and consequently it is suggested that deficiency of this protein might be responsible for the increased thrombotic tendency observed in paroxysmal nocturnal haemoglobinuria.	Glycosylphosphatidylinositols	56-85	CD59 molecule (CD59 blood group)	Homo sapiens	9-13
1371955-0	1992	Structural properties of the glycoplasmanylinositol anchor phospholipid of the complement membrane attack complex inhibitor CD59.	plasmanylinositol glycan	29-51	CD59 molecule (CD59 blood group)	Homo sapiens	124-128
1371955-0	1992	Structural properties of the glycoplasmanylinositol anchor phospholipid of the complement membrane attack complex inhibitor CD59.	Phospholipids	59-71	CD59 molecule (CD59 blood group)	Homo sapiens	124-128
1371955-1	1992	CD59, the membrane regulator of autologous C5b-9 channel formation, exhibits variable sensitivity to cleavage by phosphatidylinositol-specific phospholipase C (PI-PLC), an enzyme that releases glyco-inositolphospholipid (GPI)-anchored proteins from cell surfaces.	glyco-inositolphospholipid	193-219	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
1371955-1	1992	CD59, the membrane regulator of autologous C5b-9 channel formation, exhibits variable sensitivity to cleavage by phosphatidylinositol-specific phospholipase C (PI-PLC), an enzyme that releases glyco-inositolphospholipid (GPI)-anchored proteins from cell surfaces.	GPI 1046	221-224	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
1371955-2	1992	To determine whether the GPI-anchor phospholipid of CD59 is similar to that of decay-accelerating factor (DAF) and whether variation in its structure underlies its variable enzyme susceptibility, the GPI anchors of the two proteins expressed on erythrocytes, polymorphonuclear and mononuclear leucocytes were compared in situ and after purification.	Phospholipids	36-48	CD59 molecule (CD59 blood group)	Homo sapiens	52-56
1371955-2	1992	To determine whether the GPI-anchor phospholipid of CD59 is similar to that of decay-accelerating factor (DAF) and whether variation in its structure underlies its variable enzyme susceptibility, the GPI anchors of the two proteins expressed on erythrocytes, polymorphonuclear and mononuclear leucocytes were compared in situ and after purification.	GPI 1046	25-28	CD59 molecule (CD59 blood group)	Homo sapiens	52-56
1563250-6	1992	Urinary dopamine excretion also declined, from 322 (37) to 211 (29) mumol min-1 (p less than 0.005) but sodium excretion was unchanged.	Dopamine	8-16	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
1372260-5	1992	CD59 is detected on sodium dodecyl sulfate-polyacrylamide gel electrophoresis as a single 20-kDa molecule in 2% deoxycholate extracts of HUVEC.	Sodium Dodecyl Sulfate	20-42	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
1372260-5	1992	CD59 is detected on sodium dodecyl sulfate-polyacrylamide gel electrophoresis as a single 20-kDa molecule in 2% deoxycholate extracts of HUVEC.	polyacrylamide	43-57	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
1372260-5	1992	CD59 is detected on sodium dodecyl sulfate-polyacrylamide gel electrophoresis as a single 20-kDa molecule in 2% deoxycholate extracts of HUVEC.	Deoxycholic Acid	112-124	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
1372260-6	1992	CD59 was released from the surface of HUVEC by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor.	Phosphatidylinositols	47-67	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
1372260-6	1992	CD59 was released from the surface of HUVEC by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor.	Glycolipids	163-173	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
1597230-2	1992	A clinically relevant attenuation of the anticoagulant effect of a heparin bolus (40 U.kg-1) by a concomitant infusion of nitroglycerin (100 micrograms.min-1) was absent.	Heparin	67-74	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
1374058-1	1992	CD59 is a widely expressed cell surface glycosylphosphatidylinositol (GPI)-linked glycoprotein which acts as an inhibitor of the assembly of the membrane attack complex of autologous complement.	Glycosylphosphatidylinositols	40-68	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
1564126-7	1992	The renal clearance of prednisolone was significantly reduced after tenidap pretreatment, however (from 143 to 77 mL/min/1.73 m2).	Prednisolone	23-35	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
1740502-8	1992	The paradoxical accumulation of glycogen in the patients with NIDDM during the fast occurred despite basal rates of hepatic glucose output on the third day of the fast which were greater than those of obese nondiabetic subjects (9.0 +/- 1.2 vs. 5.6 +/- 0.5 mumol kg-1 min-1, P less than 0.05).	Glycogen	32-40	CD59 molecule (CD59 blood group)	Homo sapiens	268-273
1540646-7	1992	The reaction of the "biantennary" fraction with the synthetic substrate Arg-Pro-Pro-[3H]benzylamide was characterized in part: Km 0.7 microM, kcat 124.6 min-1, kcat/Km 1.78.10(8) M-1 min-1.	arg-pro-pro-[3h]benzylamide	72-99	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
1540646-7	1992	The reaction of the "biantennary" fraction with the synthetic substrate Arg-Pro-Pro-[3H]benzylamide was characterized in part: Km 0.7 microM, kcat 124.6 min-1, kcat/Km 1.78.10(8) M-1 min-1.	arg-pro-pro-[3h]benzylamide	72-99	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
1740413-4	1992	Interestingly, in the presence of glycosaminoglycans the maximal inhibition rate constants by HC with heparin and dermatan sulfate, respectively, were as follows: 30.0 x 10(7) and 60.5 x 10(7) for alpha-thrombin, 14.6 x 10(7) and 24.3 x 10(7) for epsilon-thrombin, and 0.017 x 10(7) and 0.034 x 10(7) M-1 min-1 for gamma T-thrombin.	Glycosaminoglycans	34-52	CD59 molecule (CD59 blood group)	Homo sapiens	305-310
1740413-4	1992	Interestingly, in the presence of glycosaminoglycans the maximal inhibition rate constants by HC with heparin and dermatan sulfate, respectively, were as follows: 30.0 x 10(7) and 60.5 x 10(7) for alpha-thrombin, 14.6 x 10(7) and 24.3 x 10(7) for epsilon-thrombin, and 0.017 x 10(7) and 0.034 x 10(7) M-1 min-1 for gamma T-thrombin.	Heparin	102-109	CD59 molecule (CD59 blood group)	Homo sapiens	305-310
1740413-4	1992	Interestingly, in the presence of glycosaminoglycans the maximal inhibition rate constants by HC with heparin and dermatan sulfate, respectively, were as follows: 30.0 x 10(7) and 60.5 x 10(7) for alpha-thrombin, 14.6 x 10(7) and 24.3 x 10(7) for epsilon-thrombin, and 0.017 x 10(7) and 0.034 x 10(7) M-1 min-1 for gamma T-thrombin.	Dermatan Sulfate	114-130	CD59 molecule (CD59 blood group)	Homo sapiens	305-310
1734672-3	1992	Total glucose disposal during insulin clamp increased from 30.4 +/- 4.3 to 38.4 +/- 4.4 mumol.kg lean body mass (LBM)-1.min-1 (P less than 0.05), insulin-stimulated glucose oxidation from 14.3 +/- 4.6 to 19.1 +/- 1.4 mumol.kg LBM-1.min-1 (P less than 0.05), and non-oxidative glucose metabolism from 16.0 +/- 3.8 to 19.3 +/- 3.6 mumol.kg LBM-1.min-1 (NS).	Glucose	6-13	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
1734672-3	1992	Total glucose disposal during insulin clamp increased from 30.4 +/- 4.3 to 38.4 +/- 4.4 mumol.kg lean body mass (LBM)-1.min-1 (P less than 0.05), insulin-stimulated glucose oxidation from 14.3 +/- 4.6 to 19.1 +/- 1.4 mumol.kg LBM-1.min-1 (P less than 0.05), and non-oxidative glucose metabolism from 16.0 +/- 3.8 to 19.3 +/- 3.6 mumol.kg LBM-1.min-1 (NS).	Glucose	165-172	CD59 molecule (CD59 blood group)	Homo sapiens	232-237
1734672-3	1992	Total glucose disposal during insulin clamp increased from 30.4 +/- 4.3 to 38.4 +/- 4.4 mumol.kg lean body mass (LBM)-1.min-1 (P less than 0.05), insulin-stimulated glucose oxidation from 14.3 +/- 4.6 to 19.1 +/- 1.4 mumol.kg LBM-1.min-1 (P less than 0.05), and non-oxidative glucose metabolism from 16.0 +/- 3.8 to 19.3 +/- 3.6 mumol.kg LBM-1.min-1 (NS).	Glucose	165-172	CD59 molecule (CD59 blood group)	Homo sapiens	232-237
1734672-3	1992	Total glucose disposal during insulin clamp increased from 30.4 +/- 4.3 to 38.4 +/- 4.4 mumol.kg lean body mass (LBM)-1.min-1 (P less than 0.05), insulin-stimulated glucose oxidation from 14.3 +/- 4.6 to 19.1 +/- 1.4 mumol.kg LBM-1.min-1 (P less than 0.05), and non-oxidative glucose metabolism from 16.0 +/- 3.8 to 19.3 +/- 3.6 mumol.kg LBM-1.min-1 (NS).	Glucose	165-172	CD59 molecule (CD59 blood group)	Homo sapiens	232-237
1734672-3	1992	Total glucose disposal during insulin clamp increased from 30.4 +/- 4.3 to 38.4 +/- 4.4 mumol.kg lean body mass (LBM)-1.min-1 (P less than 0.05), insulin-stimulated glucose oxidation from 14.3 +/- 4.6 to 19.1 +/- 1.4 mumol.kg LBM-1.min-1 (P less than 0.05), and non-oxidative glucose metabolism from 16.0 +/- 3.8 to 19.3 +/- 3.6 mumol.kg LBM-1.min-1 (NS).	Glucose	165-172	CD59 molecule (CD59 blood group)	Homo sapiens	232-237
16839965-6	1992	Dopamine at 2 mug min(-1) kg(-1) produced a transient fall in gastric pressure in all subjects, and a persistent fall in some.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	18-24
1555626-2	1992	Disopyramide was first infused intravenously at 1 mg kg-1 for 5 min followed by a continuous infusion at 0.025 mg kg-1 min-1.	Disopyramide	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
1370512-6	1992	Culturing purified human T cells in the presence of fixed CHO transfectants and submitogenic doses of PHA + rIL-1 alpha showed that: 1) CD59+ CHO transfectants induced sevenfold T cell proliferation enhancement, demonstrating the direct involvement of the CD59 molecule in T cell activation; 2) CD58+ CHO transfectants induced 20-fold T cell proliferation increase; and 3) the enhancement induced by CD58+CD59+ CHO cells was more than 40-fold.	cho	58-61	CD59 molecule (CD59 blood group)	Homo sapiens	136-140
1370512-6	1992	Culturing purified human T cells in the presence of fixed CHO transfectants and submitogenic doses of PHA + rIL-1 alpha showed that: 1) CD59+ CHO transfectants induced sevenfold T cell proliferation enhancement, demonstrating the direct involvement of the CD59 molecule in T cell activation; 2) CD58+ CHO transfectants induced 20-fold T cell proliferation increase; and 3) the enhancement induced by CD58+CD59+ CHO cells was more than 40-fold.	cho	142-145	CD59 molecule (CD59 blood group)	Homo sapiens	256-260
1370512-6	1992	Culturing purified human T cells in the presence of fixed CHO transfectants and submitogenic doses of PHA + rIL-1 alpha showed that: 1) CD59+ CHO transfectants induced sevenfold T cell proliferation enhancement, demonstrating the direct involvement of the CD59 molecule in T cell activation; 2) CD58+ CHO transfectants induced 20-fold T cell proliferation increase; and 3) the enhancement induced by CD58+CD59+ CHO cells was more than 40-fold.	cho	142-145	CD59 molecule (CD59 blood group)	Homo sapiens	256-260
1370512-6	1992	Culturing purified human T cells in the presence of fixed CHO transfectants and submitogenic doses of PHA + rIL-1 alpha showed that: 1) CD59+ CHO transfectants induced sevenfold T cell proliferation enhancement, demonstrating the direct involvement of the CD59 molecule in T cell activation; 2) CD58+ CHO transfectants induced 20-fold T cell proliferation increase; and 3) the enhancement induced by CD58+CD59+ CHO cells was more than 40-fold.	cho	142-145	CD59 molecule (CD59 blood group)	Homo sapiens	256-260
1549019-3	1992	Results indicated the standard error of estimate for the predicted oxygen values ranged from 0.11 to 0.22 l.min-1, with correlations between the actual and predicted values ranging from r = 0.22 to r = 0.50.	Oxygen	67-73	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
1549019-5	1992	The actual oxygen cost was underestimated from 0.16 to 0.29 l.min-1 (P less than 0.05) by the equation at each workload.	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
1370313-8	1992	Inab E expressed a normal amount of membrane inhibitor of reactive lysis (MIRL, CD59), a glycosyl phosphatidylinositol anchored protein that is also deficient in PNH.	Glycosylphosphatidylinositols	89-118	CD59 molecule (CD59 blood group)	Homo sapiens	80-84
1539484-7	1992	Creatinine clearances per 1.73 m2 body surface area (CCreat) in Group I were 78 +/- 14 ml.min-1, and in Group II 78 +/- 11 ml.min-1 before hypotension.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
1539484-7	1992	Creatinine clearances per 1.73 m2 body surface area (CCreat) in Group I were 78 +/- 14 ml.min-1, and in Group II 78 +/- 11 ml.min-1 before hypotension.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
1385923-2	1992	The specific binding of 3H-SQ 29548 was saturable with an association rate constant of 1 x 10(-11) mol-1 min-1 and a dissociation rate constant of 0.032 min-1.	Tritium	24-26	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
1385923-2	1992	The specific binding of 3H-SQ 29548 was saturable with an association rate constant of 1 x 10(-11) mol-1 min-1 and a dissociation rate constant of 0.032 min-1.	Tritium	24-26	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
1632314-3	1992	The apparent Km and Vmax values for thromboxane B2 were 220-250 microM and 15-30 nmol min-1 mg-1 respectively.	Thromboxane B2	36-50	CD59 molecule (CD59 blood group)	Homo sapiens	86-96
1733204-4	1992	Milrinone concentrations determined in maternal arterial blood samples obtained during 1 and 2 micrograms.kg-1.min-1 infusions were found to be within the human therapeutic range.	Milrinone	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
1733204-5	1992	Bolus injection of milrinone, as well as the lowest drug infusion, resulted in no significant changes in uterine blood flow, whereas 2 micrograms.kg-1.min-1 milrinone infusion led to a 14% to 19% increase in uterine blood flow between 120 and 240 minutes.	Milrinone	157-166	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
1733204-10	1992	Dopamine 10 micrograms.kg-1.min-1 led to a progressive decrease in fetal arterial pH and an increase in PaCO2, which may have been related to similar changes in the ewe.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	28-33
1733204-10	1992	Dopamine 10 micrograms.kg-1.min-1 led to a progressive decrease in fetal arterial pH and an increase in PaCO2, which may have been related to similar changes in the ewe.	paco2	104-109	CD59 molecule (CD59 blood group)	Homo sapiens	28-33
1536404-6	1992	A 90% response to square wave changes of gas composition was maintained up to 60 breaths.min-1 for CO2, O2, and N2O and up to 40 breaths.min-1 for the vapours when the nafion sampling tube was used.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	99-102	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
1536404-6	1992	A 90% response to square wave changes of gas composition was maintained up to 60 breaths.min-1 for CO2, O2, and N2O and up to 40 breaths.min-1 for the vapours when the nafion sampling tube was used.	Oxygen	100-102	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
1536404-6	1992	A 90% response to square wave changes of gas composition was maintained up to 60 breaths.min-1 for CO2, O2, and N2O and up to 40 breaths.min-1 for the vapours when the nafion sampling tube was used.	Nitrous Oxide	112-115	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
1476277-8	1992	Morphine administration was stopped if breathing rate decreased to less than 10 c.min-1, the patient became too sedated, or PaCO2 rose to more than 45 mmHg.	Morphine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
1554877-6	1992	The renal clearance of N4 during the first day, for four out of the six volunteers, was twice as high as on the following days (8 vs 4 ml min-1).	Folic Acid	23-25	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
1311596-11	1992	Maximal dilatation induced at the highest dose of adenosine (1220 micrograms min-1) was similar in young and elderly: 79 +/- 25% vs 88 +/- 28%, P = 0.26.	Adenosine	50-59	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
1540484-5	1992	The oral clearances of both (+)- and (-)-propranolol were significantly higher (P less than 0.05) in the young (6933 +/- 598 and 4554 +/- 372 ml min-1) than in the elderly (4548 +/- 712 and 2941 +/- 473 ml min-1).	(+)- and (-)-propranolol	28-52	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
1540484-5	1992	The oral clearances of both (+)- and (-)-propranolol were significantly higher (P less than 0.05) in the young (6933 +/- 598 and 4554 +/- 372 ml min-1) than in the elderly (4548 +/- 712 and 2941 +/- 473 ml min-1).	(+)- and (-)-propranolol	28-52	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
1733538-3	1992	Oxygen desaturation (SaO2 90%) and a decrease in respiratory rate (4.min-1) were noted 30 min after epidural meperidine was administered.	Meperidine	109-119	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
1310921-4	1992	The energy expenditure increased and was 33% higher than control (P less than 0.001) at 10 micrograms of dobutamine min-1 kg-1.	Dobutamine	105-115	CD59 molecule (CD59 blood group)	Homo sapiens	116-126
1310921-5	1992	The respiratory exchange ratio decreased from 0.85 (SEM 0.02) before infusion to 0.80 (SEM 0.01) at 10 micrograms of dobutamine min-1 kg-1, but did not alter during the placebo infusion (P less than 0.001).	Dobutamine	117-127	CD59 molecule (CD59 blood group)	Homo sapiens	128-138
1310921-11	1992	The plasma insulin concentration increased at 2 and 5 micrograms of dobutamine min-1 kg-1 (P less than 0.001) with no further rise at 10 micrograms of dobutamine min-1 kg-1.	Dobutamine	68-78	CD59 molecule (CD59 blood group)	Homo sapiens	79-89
1577035-2	1992	Dobutamine was infused at incremental doses (up to a maximum of 40 micrograms kg-1 min-1) in 52 patients with chest pain; all the patients underwent coronary angiography; significant coronary artery disease was quantitatively defined as greater than or equal to 50% diameter stenosis.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
1385118-8	1992	In conclusion, cycling at the same metabolic cost at 50 rather than 100 rev.min-1 results in greater type II fiber glycogen depletion.	Glycogen	115-123	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
1396639-5	1992	The maximal oxygen uptake (VO2max; ml.kg-1.min-1) decreased with growth in the untrained group but remained almost constant in the training group.	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
1396639-6	1992	The oxygen cost of running at 15 km.h-1 (VO2 15, ml.kg-1.min-1) was persistently lower in the trained group but decreased similarly with age in both groups.	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
1396639-12	1992	In conclusion, recent and the present findings would suggest that changes in the oxygen cost of running and VO2max (ml.kg-1.min-1) during growth may mainly be due to an overestimation of the body mass dependency of VO2 during running.	Oxygen	81-87	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
1577053-6	1992	Individual pharmacokinetic parameters were calculated: plasma clearance was 3.9 ml.min-1, elimination half-life was 12.0 h. Because of its short half-life compared to diazepam, midazolam may be used during the neonatal period to achieve rapid, brief sedation.	Midazolam	177-186	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
1606992-2	1992	The plasma clearance of total (bound + unbound) diflunisal was 10.2 ml.min-1 in the control subjects and it was not affected by cirrhosis (10.9 ml.min-1).	Diflunisal	48-58	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
1606992-4	1992	Plasma clearance of unbound diflunisal was significantly impaired in cirrhosis: 11.5 l.min-1 in control subjects vs 7.41.min-1 in cirrhotics.	Diflunisal	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
1606992-4	1992	Plasma clearance of unbound diflunisal was significantly impaired in cirrhosis: 11.5 l.min-1 in control subjects vs 7.41.min-1 in cirrhotics.	Diflunisal	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
1618252-3	1992	For women the creatinine clearance (ml.min-1) was [150-(years)].body weight (kg)/serum creatinine (mumol.l-1).	Creatinine	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
1618252-3	1992	For women the creatinine clearance (ml.min-1) was [150-(years)].body weight (kg)/serum creatinine (mumol.l-1).	Creatinine	87-97	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
1623896-7	1992	After 7 days treatment with terodiline 12.5 mg twice daily, there was a significant increase in QT by a mean of 29 ms, QTc by 15 ms and a decrease in resting heart rate by a mean of 6.7 beats.min-1.	terodiline	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
1623899-5	1992	Metamizole significantly reduced furosemide clearance (175 vs 141 ml.min-1), furosemide-stimulated plasma renin activity (1.42 vs 0.79 ng AI.ml-1.h-1) and the urinary excretion of prostacyclin metabolites and of prostaglandin F2 alpha (by 70-81%).	Dipyrone	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
1623904-4	1992	At a blood flow of 219 ml.min-1, HD clearance of vancomycin was 62.3 ml.min-1.	Vancomycin	49-59	CD59 molecule (CD59 blood group)	Homo sapiens	26-31
1623904-4	1992	At a blood flow of 219 ml.min-1, HD clearance of vancomycin was 62.3 ml.min-1.	Vancomycin	49-59	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
1425875-6	1992	The ratio of paraxanthine formation to urinary caffeine concentration (= clearance equivalent) was about 2.2 ml.min-1.kg-1 in adults, and the corresponding ratios for theophylline and theobromine were 0.43 ml.min-1.kg-1 and 0.59 ml.min-1.kg-1, respectively.	1,7-dimethylxanthine	13-25	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
1425875-6	1992	The ratio of paraxanthine formation to urinary caffeine concentration (= clearance equivalent) was about 2.2 ml.min-1.kg-1 in adults, and the corresponding ratios for theophylline and theobromine were 0.43 ml.min-1.kg-1 and 0.59 ml.min-1.kg-1, respectively.	Caffeine	47-55	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
1425886-1	1992	Noradrenaline and adrenaline were infused IV at 5 different rates (0.01-0.2 micrograms.kg.min-1) for 30 min to volunteers.	Norepinephrine	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
1451711-7	1992	Creatinine clearance was 13.2 (95% CI 6.0 to 20.4) ml.min-1 lower in users than non-users of non-aspirin non-steroidal anti-inflammatory drugs.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
1451711-7	1992	Creatinine clearance was 13.2 (95% CI 6.0 to 20.4) ml.min-1 lower in users than non-users of non-aspirin non-steroidal anti-inflammatory drugs.	Aspirin	97-104	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
1576053-4	1992	Pirenzepine significantly reduced the area under the saliva flow-time curves (7.29 +/- 3.30 g min-1 h without pirenzepine; 4.19 +/- 2.59 g min-1 h with pirenzepine, P less than 0.01).	Pirenzepine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
1576053-4	1992	Pirenzepine significantly reduced the area under the saliva flow-time curves (7.29 +/- 3.30 g min-1 h without pirenzepine; 4.19 +/- 2.59 g min-1 h with pirenzepine, P less than 0.01).	Pirenzepine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
1576053-4	1992	Pirenzepine significantly reduced the area under the saliva flow-time curves (7.29 +/- 3.30 g min-1 h without pirenzepine; 4.19 +/- 2.59 g min-1 h with pirenzepine, P less than 0.01).	Pirenzepine	152-163	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
1576057-6	1992	The partial metabolic clearance of perindopril to perindoprilat was much lower in the cirrhotics (26 +/- 12 ml min-1 vs 58 +/- 22 ml min-1).	Perindopril	35-46	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
1576057-6	1992	The partial metabolic clearance of perindopril to perindoprilat was much lower in the cirrhotics (26 +/- 12 ml min-1 vs 58 +/- 22 ml min-1).	Perindopril	35-46	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
1493852-4	1992	The total clearance of fenoterol increased with dose (1299 ml.min-1 at 0.5 microgram.min-1, 1483 ml.min-1 at 1.0 micrograms.min-1, and 1924 ml.min-1 at 2.0 micrograms.min-1), as did the apparent volume of distribution (from 49 l at the lowest to 85 l at the highest dose).	Fenoterol	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
1493852-4	1992	The total clearance of fenoterol increased with dose (1299 ml.min-1 at 0.5 microgram.min-1, 1483 ml.min-1 at 1.0 micrograms.min-1, and 1924 ml.min-1 at 2.0 micrograms.min-1), as did the apparent volume of distribution (from 49 l at the lowest to 85 l at the highest dose).	Fenoterol	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
1493852-4	1992	The total clearance of fenoterol increased with dose (1299 ml.min-1 at 0.5 microgram.min-1, 1483 ml.min-1 at 1.0 micrograms.min-1, and 1924 ml.min-1 at 2.0 micrograms.min-1), as did the apparent volume of distribution (from 49 l at the lowest to 85 l at the highest dose).	Fenoterol	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
1493852-4	1992	The total clearance of fenoterol increased with dose (1299 ml.min-1 at 0.5 microgram.min-1, 1483 ml.min-1 at 1.0 micrograms.min-1, and 1924 ml.min-1 at 2.0 micrograms.min-1), as did the apparent volume of distribution (from 49 l at the lowest to 85 l at the highest dose).	Fenoterol	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
1493852-4	1992	The total clearance of fenoterol increased with dose (1299 ml.min-1 at 0.5 microgram.min-1, 1483 ml.min-1 at 1.0 micrograms.min-1, and 1924 ml.min-1 at 2.0 micrograms.min-1), as did the apparent volume of distribution (from 49 l at the lowest to 85 l at the highest dose).	Fenoterol	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
1493852-4	1992	The total clearance of fenoterol increased with dose (1299 ml.min-1 at 0.5 microgram.min-1, 1483 ml.min-1 at 1.0 micrograms.min-1, and 1924 ml.min-1 at 2.0 micrograms.min-1), as did the apparent volume of distribution (from 49 l at the lowest to 85 l at the highest dose).	Fenoterol	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
1547805-8	1992	Although sampling times at 180, 240 and 300 min are time-consuming for patients, 51Cr-EDTA total plasma clearance can be accurately calculated for values greater than 10 ml.min-1 using the Brochner-Mortensen method.	51cr-edta	81-90	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
1379443-8	1992	Carbohydrate constitutes about 20% of the molecular mass of CD59.	Carbohydrates	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	60-64
1284955-3	1992	The dipeptidyl analog Cbz-Phe-Gly-(CH2)nS+ (CH3)2, n = 1, is a more powerful inactivator of the thiol proteinase cathepsin B, k/K &gt; 3 x 10(5) M-1 min-1, than of transglutaminases, ki(app)/Ki(app) &lt; 1.5 x 10(4) M-1 min-1.	cbz-phe-gly-(ch2)ns	22-41	CD59 molecule (CD59 blood group)	Homo sapiens	149-154
1284955-3	1992	The dipeptidyl analog Cbz-Phe-Gly-(CH2)nS+ (CH3)2, n = 1, is a more powerful inactivator of the thiol proteinase cathepsin B, k/K &gt; 3 x 10(5) M-1 min-1, than of transglutaminases, ki(app)/Ki(app) &lt; 1.5 x 10(4) M-1 min-1.	cbz-phe-gly-(ch2)ns	22-41	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
1346268-5	1992	Values for resting heart rate (epanolol, 72 +/- 11 beats min-1; metoprolol, 64 +/- 12 beats min-1; P less than 0.001), systolic blood pressure (epanolol, 143 +/- 21 mmHg; metoprolol, 137 +/- 21 mmHg; P less than 0.05) and diastolic blood pressure (epanolol, 88 +/- 10 mmHg; metoprolol, 84 +/- 11 mmHg; P less than 0.01) were all higher on epanolol treatment.	Metoprolol	64-74	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
1301788-4	1992	Laser flare count [mec-1] raises exponentially (r = 0.8; p = 0.05) with an increasing permeability coefficient to fluoresceine k(a) [10(-4)min-1].	fluoresceine k	114-128	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
1451729-7	1992	These findings suggest that quinidine inhibits the first step of flecainide metabolism, although it may also reduce its renal clearance, but to a lesser extent (3.5 vs 2.9 ml.min-1 x kg-1).	Quinidine	28-37	CD59 molecule (CD59 blood group)	Homo sapiens	175-180
1598732-10	1992	Following thiphenamil HCl, there is a significant reduction in pelvic contraction frequency, 0.6 +/- 0.6 min-1, and the opposing walls of the renal pelvis do not completely close in the formation of a bolus.	thiphenamil	10-25	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
1462481-4	1992	Renography was performed, heart rate (HR) and blood pressure (BP) measured, and hematological and biochemical tests carried out before and after intravenous infusion of dopexamine 2 micrograms kg-1 min-1 for 60 min.	dopexamine	169-179	CD59 molecule (CD59 blood group)	Homo sapiens	198-203
1462481-7	1992	The hematological and biochemical changes were transient and returned to preinfusion levels after 24 h. It is concluded that dopexamine hydrochloride 2 micrograms kg-1 min-1 increases RBF and CR in patients with CRD.	dopexamine	125-149	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
1952168-4	1991	Adenosine was given in infusion rates of 15, 30, 60, and 120 micrograms.kg-1.min-1.	Adenosine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
1952168-7	1991	Great cardiac vein flow and coronary sinus flow increased 60% with adenosine infusion of 30-60 micrograms.kg-1.min-1 and 120% with 120 micrograms.kg-1.min-1.	Adenosine	67-76	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
1952168-9	1991	Adenosine caused a significant depression of the ST segment at infusion rates of 60 and 120 micrograms.kg-1.min-1.	Adenosine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
1789949-4	1991	PAH clearance increased 26 +/- 13 mL/min/1.73 m2 on the HS/HC diet but only 10 +/- 17 mL/min/1.73 m2 on HS/LC (P = .05 between groups).	p-Aminohippuric Acid	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
1790312-16	1991	ISO data from the first dose of the multiple dose study was in agreement with these data; however, the last dose showed a higher Cls (33.0 ml min-1 kg-1) (p = 0.055).	Chlorine	129-132	CD59 molecule (CD59 blood group)	Homo sapiens	142-152
1768562-6	1991	During 150 min infusions of ICG (1.0 mg min-1) steady-state was reached within about 30 min and thereafter the plasma dye concentration remained essentially constant until the end of infusion.	Indocyanine Green	28-31	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
1768562-8	1991	Blood clearance (CLb) of ICG (15.9 +/- 2.2 ml min-1 kg-1; mean +/- s.d.	Indocyanine Green	25-28	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
1768562-11	1991	The pharmacokinetics of ICG were shown to be linear up to plasma concentrations of at least 3 micrograms ml-1 using variable infusion rates (0.5, 1.0 and 2.0 mg min-1).	Indocyanine Green	24-27	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
1768567-6	1991	oral clearance of S-(+) hexobarbitone was 1.9 +/- 0.3 and 1.8 +/- 0.2 ml min-1 kg-1, respectively, in young and elderly subjects and increased approximately six fold following 14 days of rifampicin treatment in both young (to 11.9 +/- 2.2 ml min-1 kg-1) and elderly (to 10.7 +/- 2.8 ml min-1 kg-1) subjects.	Hexobarbital	18-37	CD59 molecule (CD59 blood group)	Homo sapiens	73-83
1768567-6	1991	oral clearance of S-(+) hexobarbitone was 1.9 +/- 0.3 and 1.8 +/- 0.2 ml min-1 kg-1, respectively, in young and elderly subjects and increased approximately six fold following 14 days of rifampicin treatment in both young (to 11.9 +/- 2.2 ml min-1 kg-1) and elderly (to 10.7 +/- 2.8 ml min-1 kg-1) subjects.	Hexobarbital	18-37	CD59 molecule (CD59 blood group)	Homo sapiens	242-252
1768567-6	1991	oral clearance of S-(+) hexobarbitone was 1.9 +/- 0.3 and 1.8 +/- 0.2 ml min-1 kg-1, respectively, in young and elderly subjects and increased approximately six fold following 14 days of rifampicin treatment in both young (to 11.9 +/- 2.2 ml min-1 kg-1) and elderly (to 10.7 +/- 2.8 ml min-1 kg-1) subjects.	Hexobarbital	18-37	CD59 molecule (CD59 blood group)	Homo sapiens	242-252
1768567-8	1991	In contrast, rifampicin treatment produced a larger and a differential increase in the oral clearance of R-(-) hexobarbitone in young and elderly subjects; an 89 fold change in the young (15.6 +/- 16.4 to 1146.7 +/- 1478.0 ml min-1 kg-1) and a 19 fold change (10.3 +/- 3.0 to 199.9 +/- 98.1 ml min-1 kg-1) in the elderly.	Rifampin	13-23	CD59 molecule (CD59 blood group)	Homo sapiens	226-236
1768567-8	1991	In contrast, rifampicin treatment produced a larger and a differential increase in the oral clearance of R-(-) hexobarbitone in young and elderly subjects; an 89 fold change in the young (15.6 +/- 16.4 to 1146.7 +/- 1478.0 ml min-1 kg-1) and a 19 fold change (10.3 +/- 3.0 to 199.9 +/- 98.1 ml min-1 kg-1) in the elderly.	Rifampin	13-23	CD59 molecule (CD59 blood group)	Homo sapiens	294-304
1768567-8	1991	In contrast, rifampicin treatment produced a larger and a differential increase in the oral clearance of R-(-) hexobarbitone in young and elderly subjects; an 89 fold change in the young (15.6 +/- 16.4 to 1146.7 +/- 1478.0 ml min-1 kg-1) and a 19 fold change (10.3 +/- 3.0 to 199.9 +/- 98.1 ml min-1 kg-1) in the elderly.	r-(-) hexobarbitone	105-124	CD59 molecule (CD59 blood group)	Homo sapiens	226-236
1768567-8	1991	In contrast, rifampicin treatment produced a larger and a differential increase in the oral clearance of R-(-) hexobarbitone in young and elderly subjects; an 89 fold change in the young (15.6 +/- 16.4 to 1146.7 +/- 1478.0 ml min-1 kg-1) and a 19 fold change (10.3 +/- 3.0 to 199.9 +/- 98.1 ml min-1 kg-1) in the elderly.	r-(-) hexobarbitone	105-124	CD59 molecule (CD59 blood group)	Homo sapiens	294-304
1722443-7	1991	Infusion of islet amyloid polypeptide (150 pmol min-1 kg-1) caused a fall in serum calcium and phosphate concentrations in five patients with Paget"s disease of the bone.	Calcium	83-90	CD59 molecule (CD59 blood group)	Homo sapiens	48-58
1722443-7	1991	Infusion of islet amyloid polypeptide (150 pmol min-1 kg-1) caused a fall in serum calcium and phosphate concentrations in five patients with Paget"s disease of the bone.	Phosphates	95-104	CD59 molecule (CD59 blood group)	Homo sapiens	48-58
1770566-10	1991	Naloxone was administered intravenously in 6 patients after mastectomies or lung lobectomies (42.9%), whose respiratory rate was below 10.min-1.	Naloxone	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
1951684-4	1991	The increase in carbohydrate (CHO) oxidation (which is proportional to glycolysis) during the clamp after the 10-h fast (to 13.8 +/- 1.5 mumol.kg fat free mass-1.min-1) was completely abolished during the clamp after the 72-h fast (1.7 +/- 0.6; P less than or equal to 0.001).	Carbohydrates	16-28	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
1951684-4	1991	The increase in carbohydrate (CHO) oxidation (which is proportional to glycolysis) during the clamp after the 10-h fast (to 13.8 +/- 1.5 mumol.kg fat free mass-1.min-1) was completely abolished during the clamp after the 72-h fast (1.7 +/- 0.6; P less than or equal to 0.001).	CAV protocol	30-33	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
1751271-2	1991	Mean (SD) urinary clearance of atracurium was 0.55 (0.5) ml kg-1 min-1; that of laudanosine was 0.33 (0.2) ml kg-1 min-1.	Atracurium	31-41	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
1751271-5	1991	Mean (SD) clearances of atracurium and laudanosine in the haemofiltrate fluid were 0.11 (0.06) ml kg-1 min-1 and 0.09 (0.02) ml kg-1 min-1, respectively whilst plasma clearances were atracurium 6.7 (1.8) ml kg-1 min-1 and laudanosine 4.5 (1.8) ml kg-1 min-1.	Atracurium	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
1751271-5	1991	Mean (SD) clearances of atracurium and laudanosine in the haemofiltrate fluid were 0.11 (0.06) ml kg-1 min-1 and 0.09 (0.02) ml kg-1 min-1, respectively whilst plasma clearances were atracurium 6.7 (1.8) ml kg-1 min-1 and laudanosine 4.5 (1.8) ml kg-1 min-1.	Atracurium	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
1751271-5	1991	Mean (SD) clearances of atracurium and laudanosine in the haemofiltrate fluid were 0.11 (0.06) ml kg-1 min-1 and 0.09 (0.02) ml kg-1 min-1, respectively whilst plasma clearances were atracurium 6.7 (1.8) ml kg-1 min-1 and laudanosine 4.5 (1.8) ml kg-1 min-1.	Atracurium	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
1751271-5	1991	Mean (SD) clearances of atracurium and laudanosine in the haemofiltrate fluid were 0.11 (0.06) ml kg-1 min-1 and 0.09 (0.02) ml kg-1 min-1, respectively whilst plasma clearances were atracurium 6.7 (1.8) ml kg-1 min-1 and laudanosine 4.5 (1.8) ml kg-1 min-1.	Atracurium	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
1751271-5	1991	Mean (SD) clearances of atracurium and laudanosine in the haemofiltrate fluid were 0.11 (0.06) ml kg-1 min-1 and 0.09 (0.02) ml kg-1 min-1, respectively whilst plasma clearances were atracurium 6.7 (1.8) ml kg-1 min-1 and laudanosine 4.5 (1.8) ml kg-1 min-1.	laudanosine	39-50	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
1751273-7	1991	Milrinone was tolerated well: three patients developed tachycardia greater than 125 beat min-1, one patient developed atrial fibrillation and one patient had a short run of atrial bigemini.	Milrinone	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
1954074-4	1991	After parasympathetic blockade induced by atropine, the mean heart rate (HR) at upright rest increased from 67 to 114 beats min-1, cardiac output (CO) from 4.05 to 5.17 1 min-1 (both P less than 0.001), and the diastolic blood pressure by 13 mm Hg (P less than 0.01).	Atropine	42-50	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
1954074-4	1991	After parasympathetic blockade induced by atropine, the mean heart rate (HR) at upright rest increased from 67 to 114 beats min-1, cardiac output (CO) from 4.05 to 5.17 1 min-1 (both P less than 0.001), and the diastolic blood pressure by 13 mm Hg (P less than 0.01).	Atropine	42-50	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
1954074-10	1991	During exercise atropine increased HR from 115 to 146 beats min-1 (P less than 0.001) and CO by 12% (P less than 0.05), whereas SV decreased by 12% (P less than 0.05) and the systolic blood pressure by 16 mm Hg (P less than 0.001).	Atropine	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
1687131-4	1991	All three doses of salmeterol had significant efficacy, manifested by increased morning and evening peak expiratory flow rate (PEFR) (by 35-59 l.min-1 and 11-38 l.min-1, respectively), by reduced diurnal variation in PEFR, and by reduced requirement for additional bronchodilator for symptomatic relief.	Salmeterol Xinafoate	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
1687131-4	1991	All three doses of salmeterol had significant efficacy, manifested by increased morning and evening peak expiratory flow rate (PEFR) (by 35-59 l.min-1 and 11-38 l.min-1, respectively), by reduced diurnal variation in PEFR, and by reduced requirement for additional bronchodilator for symptomatic relief.	Salmeterol Xinafoate	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
1657144-5	1991	The complexes MgMTP2-, CoMTP2-, and MnMTP2- undergo hydrolytic cleavage with release of thiophosphate with observed first-order rate constants of 1.6 x 10(-2) min-1, 2.3 x 10(-2) min-1, and 0.6 x 10(-2) min-1, respectively, at 35 degrees C, compared with 1.1 x 10(-2) min-1 for MTP4- under the same conditions.	thiophosphoric acid	88-101	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
1687852-7	1991	Pulse rate rose by 12 min-1 (P less than 0.01) during adenosine infusion following placebo, but not after theophylline alone or theophylline and adenosine combined.	Adenosine	54-63	CD59 molecule (CD59 blood group)	Homo sapiens	22-27
1687852-9	1991	The respiratory rate fell by 6 min-1 (P less than 0.01) during treatment with adenosine only, being lower than for the two treatments containing theophylline (P less than 0.05).	Adenosine	78-87	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
1657144-5	1991	The complexes MgMTP2-, CoMTP2-, and MnMTP2- undergo hydrolytic cleavage with release of thiophosphate with observed first-order rate constants of 1.6 x 10(-2) min-1, 2.3 x 10(-2) min-1, and 0.6 x 10(-2) min-1, respectively, at 35 degrees C, compared with 1.1 x 10(-2) min-1 for MTP4- under the same conditions.	thiophosphoric acid	88-101	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
1657144-5	1991	The complexes MgMTP2-, CoMTP2-, and MnMTP2- undergo hydrolytic cleavage with release of thiophosphate with observed first-order rate constants of 1.6 x 10(-2) min-1, 2.3 x 10(-2) min-1, and 0.6 x 10(-2) min-1, respectively, at 35 degrees C, compared with 1.1 x 10(-2) min-1 for MTP4- under the same conditions.	thiophosphoric acid	88-101	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
1657144-5	1991	The complexes MgMTP2-, CoMTP2-, and MnMTP2- undergo hydrolytic cleavage with release of thiophosphate with observed first-order rate constants of 1.6 x 10(-2) min-1, 2.3 x 10(-2) min-1, and 0.6 x 10(-2) min-1, respectively, at 35 degrees C, compared with 1.1 x 10(-2) min-1 for MTP4- under the same conditions.	thiophosphoric acid	88-101	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
1657144-7	1991	At 25 degrees C and pH 12.2, the observed rate constant for tetramethylammonium MTP4- is 2.1 x 10(-3) min-1, and the estimated rate constants (min-1) for saturating alkali metals under the same conditions are as follows: Li+, 0.25 x 10(-3); Na+, 3.9 x 10(-3), K+, 6.7 x 10(-3); and Cs+, 6.7 x 10(-3).	tetramethylammonium mtp4	60-84	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
1657144-7	1991	At 25 degrees C and pH 12.2, the observed rate constant for tetramethylammonium MTP4- is 2.1 x 10(-3) min-1, and the estimated rate constants (min-1) for saturating alkali metals under the same conditions are as follows: Li+, 0.25 x 10(-3); Na+, 3.9 x 10(-3), K+, 6.7 x 10(-3); and Cs+, 6.7 x 10(-3).	Cesium	282-285	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
1789685-9	1991	In tumor-free brain, the K1 of meglumine iothalamate was 2.9 mu 1 gm-1 min-1; k2 was 0.058 min-1; and Vp was 2.1 ml 100 gm-1.	Iothalamate Meglumine	31-52	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
1928766-3	1991	After exclusion of 1 patient for intraoperative nephrectomy, 22 patients received dopamine at a rate of 3 micrograms.kg-1.min-1 during surgery and the first postoperative 48 h, and a control group of 25 patients received saline.	Dopamine	82-90	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
1681840-10	1991	Atropine was administered to two dexmedetomidine-premedicated patients because of bradycardia less than 45 beat min-1.	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
1681840-10	1991	Atropine was administered to two dexmedetomidine-premedicated patients because of bradycardia less than 45 beat min-1.	Dexmedetomidine	33-48	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
1681842-2	1991	A mean infusion rate of esmolol 50.5 micrograms kg-1 min-1 resulted in a decrease in mean arterial pressure to 63 mm Hg and heart rate to 99 beat min-1 and was associated with excellent surgical conditions.	esmolol	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
1681842-2	1991	A mean infusion rate of esmolol 50.5 micrograms kg-1 min-1 resulted in a decrease in mean arterial pressure to 63 mm Hg and heart rate to 99 beat min-1 and was associated with excellent surgical conditions.	esmolol	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
1958444-13	1991	Furthermore, in the first 30 min after administration the percent sodium fractional excretion was higher after pretreatment with probenecid even though the mean frusemide excretion rate was more than three times with frusemide alone than with probenecid-frusemide (374.4 micrograms min-1 vs 119.1 micrograms min-1).	Probenecid	129-139	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
1958444-13	1991	Furthermore, in the first 30 min after administration the percent sodium fractional excretion was higher after pretreatment with probenecid even though the mean frusemide excretion rate was more than three times with frusemide alone than with probenecid-frusemide (374.4 micrograms min-1 vs 119.1 micrograms min-1).	Probenecid	129-139	CD59 molecule (CD59 blood group)	Homo sapiens	308-313
1657491-5	1991	Acetazolamide induced a dramatic fall in glomerular filtration rate in both diabetic patients and control subjects (from 138 +/- 5 to 114 +/- 4 and from 127 +/- 3 to 113 +/- 2 ml min-1 1.73 m-2, respectively, P less than 0.0001).	Acetazolamide	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
1838062-6	1991	Basal hepatic glucose production was higher in subjects with Impaired Glucose Tolerance (6.3 +/- 0.4 vs 4.5 +/- 0.6 mol kg-1 min-1, p less than 0.02) and remained elevated during infusion (p less than 0.01).	Glucose	14-21	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
1838062-7	1991	Glucose disposal per unit circulating insulin at the maximal infusion rate was approximately half in subjects with Impaired Glucose Tolerance (0.022 +/- 0.010 vs 0.047 +/- 0.017 ml kg-1 min-1 mU-1 l, p less than 0.01).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
1936594-6	1991	Ethanol inhibited gluconeogenesis from lactate by 71 +/- 5% (0.5 +/- 0.2 vs. 1.8 +/- 0.1 mumol glucose.kg-1.min-1, 240-300 min, P less than 0.001; ethanol vs. saline, P less than 0.001) and from glycerol by 65 +/- 6% (0.8 +/- 0.2 vs. 2.3 +/- 0.6 mumol glucose.kg.min-1, P less than 0.001).	Ethanol	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	263-268
1936594-7	1991	Total HGO rate remained unchanged and averaged 12.8 +/- 1.8 and 11.8 +/- 2.1 mumol.kg-1.min-1 in the saline and ethanol studies, respectively (NS).	Sodium Chloride	101-107	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
1718774-3	1991	A corresponding mean fluorescein permeability across this surface of 2.5 x 10(-5) cm min-1 was calculated.	Fluorescein	21-32	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
1752291-7	1991	Insulin sensitivity increased significantly during treatment with enalapril (with enalapril: Ins I: 11.3 +/- 3.0, Ins II: 20.0 +/- 3.4 and Ins III: 20.6 +/- 3.9 mg kg-1 min-1 glucose (mean +/- SD); without enalapril: Ins I: 8.7 +/- 2.3, Ins II: 13.7 +/- 3.0 and Ins III: 15.5 +/- 3.1 mg kg-1 min-1 glucose; P less than 0.05).	Enalapril	66-75	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
1752291-7	1991	Insulin sensitivity increased significantly during treatment with enalapril (with enalapril: Ins I: 11.3 +/- 3.0, Ins II: 20.0 +/- 3.4 and Ins III: 20.6 +/- 3.9 mg kg-1 min-1 glucose (mean +/- SD); without enalapril: Ins I: 8.7 +/- 2.3, Ins II: 13.7 +/- 3.0 and Ins III: 15.5 +/- 3.1 mg kg-1 min-1 glucose; P less than 0.05).	Enalapril	66-75	CD59 molecule (CD59 blood group)	Homo sapiens	292-297
1655647-3	1991	To this end, two strictly standardized mental stress tests were performed in 14 normotensive men during and 1 hour after double-blind infusion of epinephrine (50 ng x kg-1 x min-1) or placebo given in random order.	Epinephrine	146-157	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
1919425-6	1991	The maximal tolerable dose of adenosine was 108 +/- 6 micrograms kg-1 min-1.	Adenosine	30-39	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
1766102-6	1991	These results suggest that RC-100 could be useful either for CRC and for WB even with the rapid flow rate under 100 ml.min-1.	RC-100	27-33	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
1836828-4	1991	Maximal oxygen uptake (VO2max) for the male population was 2.23 l.min-1 (32.9 ml.kg-1.min-1).	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
1836828-4	1991	Maximal oxygen uptake (VO2max) for the male population was 2.23 l.min-1 (32.9 ml.kg-1.min-1).	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
1777375-5	1991	Terfenadine improved 04.00 h baseline mean PEFR from 242 to 278 l min-1 (P less than 0.05) but a 38 l min-1 diurnal variation in mean PEFR persisted (P less than 0.05).	Terfenadine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
1777376-6	1991	The addition of nisoldipine was also associated with significant changes in apparent liver blood flow (measured by indocyanine green clearance) from 1.4 to 2.4 l min-1 in the atenolol group and from 1.3 to 2.3 l min-1 in the propranolol group.	Nisoldipine	16-27	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
1777376-6	1991	The addition of nisoldipine was also associated with significant changes in apparent liver blood flow (measured by indocyanine green clearance) from 1.4 to 2.4 l min-1 in the atenolol group and from 1.3 to 2.3 l min-1 in the propranolol group.	Nisoldipine	16-27	CD59 molecule (CD59 blood group)	Homo sapiens	212-217
1777376-6	1991	The addition of nisoldipine was also associated with significant changes in apparent liver blood flow (measured by indocyanine green clearance) from 1.4 to 2.4 l min-1 in the atenolol group and from 1.3 to 2.3 l min-1 in the propranolol group.	Indocyanine Green	115-132	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
1683549-8	1991	The creatinine clearance was 48.2 +/- 17.4 ml min-1 (mean +/- s.d.).	Creatinine	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
1934944-3	1991	Thirty-seven patients (six female) aged 37-74 years with IHD, verified by coronary angiography, were given up to 200 micrograms kg-1 min-1 (mean 155 +/- 5) adenosine i.v.	Adenosine	156-165	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
1721817-2	1991	These factors are glycolipid-anchored membrane proteins that either induce C3 convertase dissociation (for example decay-accelerating factor) or prevent the full development of the membrane attack complex (for example homologous restriction factor and CD59).	Glycolipids	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	252-256
1684980-12	1991	There is a progressive increase in serum concentrations of clarithromycin and 14-OH-(R)-clarithromycin with renal impairment so that doses may need to be reduced in severe impairment (glomerular filtration rate less than 30 ml min-1).	Clarithromycin	59-73	CD59 molecule (CD59 blood group)	Homo sapiens	227-232
1684980-12	1991	There is a progressive increase in serum concentrations of clarithromycin and 14-OH-(R)-clarithromycin with renal impairment so that doses may need to be reduced in severe impairment (glomerular filtration rate less than 30 ml min-1).	14-oh-(r)-clarithromycin	78-102	CD59 molecule (CD59 blood group)	Homo sapiens	227-232
1715364-1	1991	mAb against human glycosyl-phosphatidylinositol-linked leucocyte surface Ag CD59 and CD55 immunoprecipitated from detergent lysates of HPB ALL cell line in addition to the respective Ag a common 80-kDa glycoprotein component and (glyco)lipids.	Glycosylphosphatidylinositols	18-47	CD59 molecule (CD59 blood group)	Homo sapiens	76-80
1957331-11	1991	The total and renal clearances of digoxin were, on average, 193 +/- 25 ml min-1 and 152 +/- 24 ml min-1.	Digoxin	34-41	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
1957331-21	1991	Renal clearance and mean oral residence time for digoxin were on average 176 +/- 28 ml min-1 and 37 +/- 4 h after p.o.	Digoxin	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	87-99
1908186-3	1991	Lysine concentration dependence data were fit by a two-system model with Km values of 1.0 +/- 0.8 and 223 +/- 57 microM and Vmax values of 0.06 +/- 0.03 and 24.0 +/- 5.8 pmol.mg protein-1.min-1.	Lysine	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
1859019-9	1991	Indocyanine green clearance was better preserved during sevoflurane anesthesia (39.7 +/- 12.0 ml.min-1) than during halothane anesthesia (30.9 +/- 8.4 ml.min-1; P less than 0.05).	Indocyanine Green	0-17	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
1859019-9	1991	Indocyanine green clearance was better preserved during sevoflurane anesthesia (39.7 +/- 12.0 ml.min-1) than during halothane anesthesia (30.9 +/- 8.4 ml.min-1; P less than 0.05).	Indocyanine Green	0-17	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
1912989-4	1991	A dose of 0.1 nmol kg-1 human proendothelin [1-38] caused a slight pressor effect (maximum 5 +/- 2 mmHg), but a clear bradycardia (maximum -29 +/- 7 beats min-1).	proendothelin	30-43	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
1912989-7	1991	A dose of 1.0 nmol kg-1 human proendothelin [1-38] caused a gradual hypertension (maximum 42 +/- 4 mmHg at 10 min) and a profound bradycardia (-149 +/- 10 beats min-1 at 30 min).	proendothelin	30-43	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
1936660-2	1991	The effect of 53 h of 2.2 mg glucose.kg ideal body weight-1.min-1 was examined in four normal male subjects.	Glucose	29-36	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
1655438-2	1991	For this purpose, a four-point dose-response curve was prepared for dobutamine starting with an initial dose of 2.5 micrograms kg-1 min-1, which was increased by 2.5 micrograms kg-1 min-1 at a time up to altogether 10 micrograms kg-1 min-1.	Dobutamine	68-78	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
1655438-2	1991	For this purpose, a four-point dose-response curve was prepared for dobutamine starting with an initial dose of 2.5 micrograms kg-1 min-1, which was increased by 2.5 micrograms kg-1 min-1 at a time up to altogether 10 micrograms kg-1 min-1.	Dobutamine	68-78	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
1655438-2	1991	For this purpose, a four-point dose-response curve was prepared for dobutamine starting with an initial dose of 2.5 micrograms kg-1 min-1, which was increased by 2.5 micrograms kg-1 min-1 at a time up to altogether 10 micrograms kg-1 min-1.	Dobutamine	68-78	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
1885227-4	1991	Hypertensive patients with elevated sodium-lithium countertransport activity showed elevated glomerular filtration rate (118 +/- 2 versus 109 +/- 2 ml/min.1.73 m2; p less than 0.001), albumin excretion rate (23 +/- 3 versus 14 +/- 2 micrograms/min; p less than 0.001), larger kidney volume (250 +/- 15 versus 203 +/- 13 ml.1.73 m2; p less than 0.01), lower lithium clearance rate (26.7 +/- 0.3 versus 28.9 +/- 0.3 ml/min.1.73 m2; p less than 0.01), and higher total body exchangeable sodium (2,716 +/- 33 versus 2,485 +/- 41 mmol.1.73 m2; p less than 0.01).	Sodium	36-42	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
1885227-4	1991	Hypertensive patients with elevated sodium-lithium countertransport activity showed elevated glomerular filtration rate (118 +/- 2 versus 109 +/- 2 ml/min.1.73 m2; p less than 0.001), albumin excretion rate (23 +/- 3 versus 14 +/- 2 micrograms/min; p less than 0.001), larger kidney volume (250 +/- 15 versus 203 +/- 13 ml.1.73 m2; p less than 0.01), lower lithium clearance rate (26.7 +/- 0.3 versus 28.9 +/- 0.3 ml/min.1.73 m2; p less than 0.01), and higher total body exchangeable sodium (2,716 +/- 33 versus 2,485 +/- 41 mmol.1.73 m2; p less than 0.01).	Sodium	36-42	CD59 molecule (CD59 blood group)	Homo sapiens	417-422
1885227-4	1991	Hypertensive patients with elevated sodium-lithium countertransport activity showed elevated glomerular filtration rate (118 +/- 2 versus 109 +/- 2 ml/min.1.73 m2; p less than 0.001), albumin excretion rate (23 +/- 3 versus 14 +/- 2 micrograms/min; p less than 0.001), larger kidney volume (250 +/- 15 versus 203 +/- 13 ml.1.73 m2; p less than 0.01), lower lithium clearance rate (26.7 +/- 0.3 versus 28.9 +/- 0.3 ml/min.1.73 m2; p less than 0.01), and higher total body exchangeable sodium (2,716 +/- 33 versus 2,485 +/- 41 mmol.1.73 m2; p less than 0.01).	Lithium	43-50	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
1885227-4	1991	Hypertensive patients with elevated sodium-lithium countertransport activity showed elevated glomerular filtration rate (118 +/- 2 versus 109 +/- 2 ml/min.1.73 m2; p less than 0.001), albumin excretion rate (23 +/- 3 versus 14 +/- 2 micrograms/min; p less than 0.001), larger kidney volume (250 +/- 15 versus 203 +/- 13 ml.1.73 m2; p less than 0.01), lower lithium clearance rate (26.7 +/- 0.3 versus 28.9 +/- 0.3 ml/min.1.73 m2; p less than 0.01), and higher total body exchangeable sodium (2,716 +/- 33 versus 2,485 +/- 41 mmol.1.73 m2; p less than 0.01).	Lithium	43-50	CD59 molecule (CD59 blood group)	Homo sapiens	417-422
1830889-3	1991	Under control conditions (Na HCO3- = 13 mM, perfusion rate approximately 17 nl/min-1) net bicarbonate transport (JHCO3-) was unsaturated, flow- and concentration-dependent, and increased linearly until a bicarbonate load of 1,400 pmol.min-1 was reached.	Bicarbonates	90-101	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
1908864-7	1991	When misoprostol was given with the indomethacin, four of these six patients did not experience a decline in GFR (baseline GFR for six patients: 75.4 +/- 6.6 mL/min/1.73m2, GFR after indomethacin: 57.8 +/- 9.5 mL/min/1.73m2, GFR with combination of indomethacin and misoprostol: 69.7 +/- 3.5 mL/min/1.73m2.	Misoprostol	5-16	CD59 molecule (CD59 blood group)	Homo sapiens	213-218
1908864-7	1991	When misoprostol was given with the indomethacin, four of these six patients did not experience a decline in GFR (baseline GFR for six patients: 75.4 +/- 6.6 mL/min/1.73m2, GFR after indomethacin: 57.8 +/- 9.5 mL/min/1.73m2, GFR with combination of indomethacin and misoprostol: 69.7 +/- 3.5 mL/min/1.73m2.	Misoprostol	5-16	CD59 molecule (CD59 blood group)	Homo sapiens	213-218
1875347-3	1991	19,19-Difluoro steroid 18 and 19-acetylenic alcohol 25, a weak competitive inhibitor (Ki = 7.75 microM), caused a time-dependent, pseudo-first-order inactivation of aromatase activity with kinact"s of 0.0213 and 0.1053 min-1 for compounds 18 and 25, respectively.	19-difluoro steroid	3-22	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
1875347-3	1991	19,19-Difluoro steroid 18 and 19-acetylenic alcohol 25, a weak competitive inhibitor (Ki = 7.75 microM), caused a time-dependent, pseudo-first-order inactivation of aromatase activity with kinact"s of 0.0213 and 0.1053 min-1 for compounds 18 and 25, respectively.	acetylenic alcohol	32-51	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
1942772-4	1991	The glomerular filtration rate and renal plasma flow were significantly depressed below normal values in transplant recipients given cyclosporine, averaging 35 +/- 8 and 325 +/- 94 ml/min/1.73 m2, respectively.	Cyclosporine	133-145	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
1712784-3	1991	After cloning and selection, the transfected cells were maintained in media containing various concentrations of methotrexate, which induced surface expression of up to 4.2 x 10(6) molecules of CD59/cell.	Methotrexate	113-125	CD59 molecule (CD59 blood group)	Homo sapiens	194-198
1676598-5	1991	The rate of cyclic GMP synthesis from GTP in rod disk membranes was about 50 pmol min-1 (nmol of rhodopsin)-1.	Guanosine Triphosphate	38-41	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
1951063-2	1991	By using the soft glass (II) reactor as the reaction vessel for hydrolysis experiments, trimethoxysilane and tetramethoxysilane were found to be very unstable in 0.15 M sodium phosphate buffer (pH 7.4) and 10% rat serum (0.15 M sodium phosphate buffer, pH 7.4) with similar rates of hydrolysis at greater than 3.0 min-1 (t 1/2 less than 0.23 min).	trimethoxysilane	88-104	CD59 molecule (CD59 blood group)	Homo sapiens	314-319
1951063-2	1991	By using the soft glass (II) reactor as the reaction vessel for hydrolysis experiments, trimethoxysilane and tetramethoxysilane were found to be very unstable in 0.15 M sodium phosphate buffer (pH 7.4) and 10% rat serum (0.15 M sodium phosphate buffer, pH 7.4) with similar rates of hydrolysis at greater than 3.0 min-1 (t 1/2 less than 0.23 min).	tetramethoxysilane	109-127	CD59 molecule (CD59 blood group)	Homo sapiens	314-319
1951063-3	1991	Under similar conditions, however, the rate of hydrolysis for tetramethoxysilane in deionized water was measured to be considerably slower (k = 0.022 min-1; t 1/2 = 32 min) than that of trimethoxysilane (k greater than 8.1 min-1, t 1/2 less than 0.09 min).	tetramethoxysilane	62-80	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
1951063-3	1991	Under similar conditions, however, the rate of hydrolysis for tetramethoxysilane in deionized water was measured to be considerably slower (k = 0.022 min-1; t 1/2 = 32 min) than that of trimethoxysilane (k greater than 8.1 min-1, t 1/2 less than 0.09 min).	tetramethoxysilane	62-80	CD59 molecule (CD59 blood group)	Homo sapiens	223-228
1951063-3	1991	Under similar conditions, however, the rate of hydrolysis for tetramethoxysilane in deionized water was measured to be considerably slower (k = 0.022 min-1; t 1/2 = 32 min) than that of trimethoxysilane (k greater than 8.1 min-1, t 1/2 less than 0.09 min).	Water	94-99	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
1951063-3	1991	Under similar conditions, however, the rate of hydrolysis for tetramethoxysilane in deionized water was measured to be considerably slower (k = 0.022 min-1; t 1/2 = 32 min) than that of trimethoxysilane (k greater than 8.1 min-1, t 1/2 less than 0.09 min).	Water	94-99	CD59 molecule (CD59 blood group)	Homo sapiens	223-228
1951063-3	1991	Under similar conditions, however, the rate of hydrolysis for tetramethoxysilane in deionized water was measured to be considerably slower (k = 0.022 min-1; t 1/2 = 32 min) than that of trimethoxysilane (k greater than 8.1 min-1, t 1/2 less than 0.09 min).	trimethoxysilane	186-202	CD59 molecule (CD59 blood group)	Homo sapiens	223-228
1951063-4	1991	However, the rates of hydrolysis for methyltrimethoxysilane in water, sodium phosphate buffer at pH 7.4, and 10% rat serum were measured to be 0.03 min-1 (t 1/2 = 24 min), 0.10 min-1 (t 1/2 = 6.7 min), and 0.08 min-1 (t 1/2 = 8.6 min), respectively.	methyltrimethoxysilane	37-59	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
1951063-4	1991	However, the rates of hydrolysis for methyltrimethoxysilane in water, sodium phosphate buffer at pH 7.4, and 10% rat serum were measured to be 0.03 min-1 (t 1/2 = 24 min), 0.10 min-1 (t 1/2 = 6.7 min), and 0.08 min-1 (t 1/2 = 8.6 min), respectively.	methyltrimethoxysilane	37-59	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
1951063-4	1991	However, the rates of hydrolysis for methyltrimethoxysilane in water, sodium phosphate buffer at pH 7.4, and 10% rat serum were measured to be 0.03 min-1 (t 1/2 = 24 min), 0.10 min-1 (t 1/2 = 6.7 min), and 0.08 min-1 (t 1/2 = 8.6 min), respectively.	methyltrimethoxysilane	37-59	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
1951063-4	1991	However, the rates of hydrolysis for methyltrimethoxysilane in water, sodium phosphate buffer at pH 7.4, and 10% rat serum were measured to be 0.03 min-1 (t 1/2 = 24 min), 0.10 min-1 (t 1/2 = 6.7 min), and 0.08 min-1 (t 1/2 = 8.6 min), respectively.	Water	63-68	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
1951063-4	1991	However, the rates of hydrolysis for methyltrimethoxysilane in water, sodium phosphate buffer at pH 7.4, and 10% rat serum were measured to be 0.03 min-1 (t 1/2 = 24 min), 0.10 min-1 (t 1/2 = 6.7 min), and 0.08 min-1 (t 1/2 = 8.6 min), respectively.	sodium phosphate	70-86	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
1858855-2	1991	The frequency of oscillations increased in graded fashion with [CCh] between 25 nM (2.7 +/- 0.6 min-1) and 250 nM (11.8 +/- 1.4 min-1), whereas the amplitude of the spikes was independent of [CCh].	Carbachol	64-67	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
2064120-2	1991	At 1 month the response to a single breath of oxygen during normoxia was a decrease in minute ventilation of 264 +/- 34.2 (SEM) ml.min-1 during the 10-s period following the stimulus (p less than 0.001).	Oxygen	46-52	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
2064120-5	1991	By the age of 3 months, the absolute ventilatory response to a single breath of oxygen increased significantly in normoxia by 118 +/- 35.2 ml.min-1 (p less than 0.01); the test response to breathing 16% oxygen paralleled the response to normoxia and was on average 254 +/- 26.6 ml.min-1 larger than the response when breathing air (p less than 0.001).	Oxygen	80-86	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
2064120-5	1991	By the age of 3 months, the absolute ventilatory response to a single breath of oxygen increased significantly in normoxia by 118 +/- 35.2 ml.min-1 (p less than 0.01); the test response to breathing 16% oxygen paralleled the response to normoxia and was on average 254 +/- 26.6 ml.min-1 larger than the response when breathing air (p less than 0.001).	Oxygen	80-86	CD59 molecule (CD59 blood group)	Homo sapiens	281-286
1677545-3	1991	Effective vecuronium infusion requirements averaged 1.5 +/- 0.1 micrograms.kg-1.min-1 (mean +/- SEM) during isoflurane-narcotic-nitrous oxide anesthesia, 1.9 +/- 0.1 micrograms.kg-1.min-1 during halothane-narcotic-nitrous oxide anesthesia, and 2.4 +/- 0.3 micrograms.kg-1.min-1 during narcotic-nitrous oxide anesthesia.	Vecuronium Bromide	10-20	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
1677545-3	1991	Effective vecuronium infusion requirements averaged 1.5 +/- 0.1 micrograms.kg-1.min-1 (mean +/- SEM) during isoflurane-narcotic-nitrous oxide anesthesia, 1.9 +/- 0.1 micrograms.kg-1.min-1 during halothane-narcotic-nitrous oxide anesthesia, and 2.4 +/- 0.3 micrograms.kg-1.min-1 during narcotic-nitrous oxide anesthesia.	Isoflurane	108-118	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
1677545-3	1991	Effective vecuronium infusion requirements averaged 1.5 +/- 0.1 micrograms.kg-1.min-1 (mean +/- SEM) during isoflurane-narcotic-nitrous oxide anesthesia, 1.9 +/- 0.1 micrograms.kg-1.min-1 during halothane-narcotic-nitrous oxide anesthesia, and 2.4 +/- 0.3 micrograms.kg-1.min-1 during narcotic-nitrous oxide anesthesia.	Nitrous Oxide	128-141	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
1858990-3	1991	Atropine plus meperidine significantly increased energy expenditure above predicted values (2061 +/- 365 vs 1714 +/- 361 kcal/24 h, P = 0.004), calculated using the Harris-Benedict equation, based on sex, weight, height, and age, as well as increased oxygen consumption above levels seen with diazepam premedication (160 +/- 29 vs 137 +/- 17 mL.min-1.	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	345-350
1858990-3	1991	Atropine plus meperidine significantly increased energy expenditure above predicted values (2061 +/- 365 vs 1714 +/- 361 kcal/24 h, P = 0.004), calculated using the Harris-Benedict equation, based on sex, weight, height, and age, as well as increased oxygen consumption above levels seen with diazepam premedication (160 +/- 29 vs 137 +/- 17 mL.min-1.	Meperidine	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	345-350
1928710-6	1991	After bupivacaine was injected the loss of sympathetic tone produced a systolic arterial blood pressure decrease from 174 +/- 22 to 136 +/- 28 mmHg (p less than 0.05) and a decrease in heart rate from 73 +/- 12 to 66 +/- 10 min-1 (p less than 0.05).	Bupivacaine	6-17	CD59 molecule (CD59 blood group)	Homo sapiens	224-229
1832287-11	1991	Concomitant infusion of ANF 3 pmol kg-1 min-1 and 15 pmol kg-1 min-1 significantly attenuated this rise in plasma aldosterone to approximately 130% (P less than 0.05) and 110% (P less than 0.01) of baseline values respectively.	Aldosterone	114-125	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
1832287-11	1991	Concomitant infusion of ANF 3 pmol kg-1 min-1 and 15 pmol kg-1 min-1 significantly attenuated this rise in plasma aldosterone to approximately 130% (P less than 0.05) and 110% (P less than 0.01) of baseline values respectively.	Aldosterone	114-125	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
1859754-5	1991	infusions of adrenaline (1-5 micrograms min-1).	Epinephrine	13-23	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
1888639-8	1991	Morphine clearance was 3.6 +/- 0.9 ml min-1 kg-1, the elimination half-life was 8.9 +/- 3.3 h and the volume of distribution was 2.7 +/- 1.01 kg-1.	Morphine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	38-48
1888642-4	1991	The plasma clearance of nicardipine was significantly lower at 6.5 ml min-1 kg-1 in patients with impaired renal function, compared with a mean value of 10.4 in patients with normal renal function and with 12.5 ml min-1 kg-1 in patients on regular haemodialysis treatment.	Nicardipine	24-35	CD59 molecule (CD59 blood group)	Homo sapiens	70-80
1888642-4	1991	The plasma clearance of nicardipine was significantly lower at 6.5 ml min-1 kg-1 in patients with impaired renal function, compared with a mean value of 10.4 in patients with normal renal function and with 12.5 ml min-1 kg-1 in patients on regular haemodialysis treatment.	Nicardipine	24-35	CD59 molecule (CD59 blood group)	Homo sapiens	214-224
1653676-2	1991	The amount of O2- production was significantly increased in diabetic serum 0.41 +/- 0.04 (+/- SD) vs 0.14 +/- 0.04 mumol l-1 min-1, p less than 0.001) and correlated with fasting plasma glucose and glycosylated protein levels in both diabetic (r = 0.72, p less than 0.01, and r = 0.62, p less than 0.05) and normal r = 0.75, p less than 0.01 and r = 0.64, p less than 0.05) subjects.	Superoxides	14-16	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
1653676-3	1991	Improved metabolic control in the diabetic patients was associated with a reduction of serum O2- production (0.28 +/- 0.06 mumol l-1 min-1, p less than 0.01), but the correlation between O2- levels and fasting plasma glucose and glycosylated protein concentrations was retained (r = 0.86 and r = 0.72, respectively, both p less than 0.01).	Superoxides	93-95	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
1828802-7	1991	For example, the ADP-heat-activated enzyme in presence of 1 mM Mg2+ binds ADP with a rate constant of 0.5 x 10(6) M-1 min-1 to give an enzyme with two ADP at noncatalytic sites with a Kd of about 0.1 microM.	Adenosine Diphosphate	17-20	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
1830889-3	1991	Under control conditions (Na HCO3- = 13 mM, perfusion rate approximately 17 nl/min-1) net bicarbonate transport (JHCO3-) was unsaturated, flow- and concentration-dependent, and increased linearly until a bicarbonate load of 1,400 pmol.min-1 was reached.	Bicarbonates	90-101	CD59 molecule (CD59 blood group)	Homo sapiens	235-240
1828802-7	1991	For example, the ADP-heat-activated enzyme in presence of 1 mM Mg2+ binds ADP with a rate constant of 0.5 x 10(6) M-1 min-1 to give an enzyme with two ADP at noncatalytic sites with a Kd of about 0.1 microM.	magnesium ion	63-67	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
1828802-7	1991	For example, the ADP-heat-activated enzyme in presence of 1 mM Mg2+ binds ADP with a rate constant of 0.5 x 10(6) M-1 min-1 to give an enzyme with two ADP at noncatalytic sites with a Kd of about 0.1 microM.	Adenosine Diphosphate	74-77	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
1828802-7	1991	For example, the ADP-heat-activated enzyme in presence of 1 mM Mg2+ binds ADP with a rate constant of 0.5 x 10(6) M-1 min-1 to give an enzyme with two ADP at noncatalytic sites with a Kd of about 0.1 microM.	Adenosine Diphosphate	74-77	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
1710519-2	1991	Following treatment with AET, erythrocyte MIRL and CR1 were no longer recognized in situ by antibodies, and antibody binding to DAF was diminished by approximately 50%.	2-(2-Aminoethyl)isothiourea dihydrobromide	25-28	CD59 molecule (CD59 blood group)	Homo sapiens	42-46
1710519-5	1991	Treatment of normal erythrocytes with AET induced susceptibility to cobra venom factor-initiated hemolysis, indicating that the functional activity of MIRL had been destroyed.	2-(2-Aminoethyl)isothiourea dihydrobromide	38-41	CD59 molecule (CD59 blood group)	Homo sapiens	151-155
1867967-2	1991	The total oxazepam clearance was 1.24 (0.91-1.80) ml min-1 kg-1 (median and range) and 1.44 (0.88-2.13) ml min-1 kg-1 in the elderly and young, respectively (NS), and the elimination half-lives were 8.1 (5.5-10.8) h and 5.7 (4.9-6.2) h. respectively (P less than 0.01).	Oxazepam	10-18	CD59 molecule (CD59 blood group)	Homo sapiens	53-63
1867967-4	1991	Clearance of unbound oxazepam was lower in the elderly, median values being 13.8 (7.1-21.1) ml min-1 kg-1 compared with 30.3 (18.3-41.5) ml min-1 kg-1 in the young (P less than 0.0001).	Oxazepam	21-29	CD59 molecule (CD59 blood group)	Homo sapiens	95-105
1907840-3	1991	We have therefore investigated the effects of oral lithium carbonate (500 mg) on the natriuretic response to a pressor dose of tyramine (15 micrograms kg-1 min-1) in six normal volunteers.	Tyramine	127-135	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
1889941-7	1991	Mean target heart rate range (THRR) calculated from TS peak HR (144-176 bt.min-1) was significantly lower than THRR calculated from age-predicted max HR (151-187 bt.min-1) and TR peak HR (151-186 bt.min-1).	thrr	30-34	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
2018219-3	1991	Significant transpulmonary gradient of plasma dopamine was observed with infusions at rates of 1.0 and 2.0 micrograms.kg-1.min-1, but not at 0.5 micrograms.kg-1.min-1.	Dopamine	46-54	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
2031819-8	1991	HR remained unchanged after saline injection, but increased slightly 5 min after atropine injection (mean 78 (SD 15) beat min-1 vs 87 (20) beat min-1 (P less than 0.05).	Atropine	81-89	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
2031819-10	1991	The maximum increase in HR was greater in the atropine group than in the saline group (31 (4) beat min-1 vs 26 (11) beat min-1 (P less than 0.05).	Atropine	46-54	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
2031819-10	1991	The maximum increase in HR was greater in the atropine group than in the saline group (31 (4) beat min-1 vs 26 (11) beat min-1 (P less than 0.05).	Atropine	46-54	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
2031819-11	1991	However, when individual maximum HR changes are considered, five patients in the saline group and four in the atropine group had an increase less than or equal to 10 beat min-1, and three patients in the saline group had no change or a decrease in HR.	Sodium Chloride	81-87	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
2031819-11	1991	However, when individual maximum HR changes are considered, five patients in the saline group and four in the atropine group had an increase less than or equal to 10 beat min-1, and three patients in the saline group had no change or a decrease in HR.	Atropine	110-118	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
2031819-12	1991	Defining a positive result to a test dose as an increase in HR of greater than 10 beat min-1, the sensitivity of the adrenaline test dose was 83 (5.5)% in the saline group and 91 (3.5)% in the atropine group (ns).	Epinephrine	117-127	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
1874263-4	1991	Theophylline increased mean resting heart rate (51 +/- 6 versus 67 +/- 13 beats.min-1, P less than 0.01), mean 24-h heart rate (51 +/- 6 versus 68 +/- 14 beats.min-1, P less than 0.01) and minimal 24-h heart rate (32 +/- 6 versus 42 +/- 11 beats.min-1, P less than 0.01).	Theophylline	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
1874263-4	1991	Theophylline increased mean resting heart rate (51 +/- 6 versus 67 +/- 13 beats.min-1, P less than 0.01), mean 24-h heart rate (51 +/- 6 versus 68 +/- 14 beats.min-1, P less than 0.01) and minimal 24-h heart rate (32 +/- 6 versus 42 +/- 11 beats.min-1, P less than 0.01).	Theophylline	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
1874263-4	1991	Theophylline increased mean resting heart rate (51 +/- 6 versus 67 +/- 13 beats.min-1, P less than 0.01), mean 24-h heart rate (51 +/- 6 versus 68 +/- 14 beats.min-1, P less than 0.01) and minimal 24-h heart rate (32 +/- 6 versus 42 +/- 11 beats.min-1, P less than 0.01).	Theophylline	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
2027756-3	1991	The results indicate two waves of crosslinking [rate constants (0.2-0.3) min-1 and (0.015-0.025) min-1] that correlate with changes in ultra violet absorbance and ethidium bromide dependent fluorescence intensity, previously interpreted in terms of two consecutive, local conformational rearrangements of platinum-DNA (Schaller, W., Reisner, H., and Holler, E. (1987) Biochemistry 26, 943-950).	ultra violet	135-147	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
1710238-1	1991	The CD59 Ag is a 20-kDa protein that is widely expressed on most leukocytes and RBC, is coupled to the membrane by a phosphatidylinositol-glycan anchoring structure, plays a role in cell interaction between monocytes and T cells, and also functions as an inhibitor of cytolysis by the terminal C components C5b-9.	Phosphatidylinositols	117-137	CD59 molecule (CD59 blood group)	Homo sapiens	4-8
1710238-1	1991	The CD59 Ag is a 20-kDa protein that is widely expressed on most leukocytes and RBC, is coupled to the membrane by a phosphatidylinositol-glycan anchoring structure, plays a role in cell interaction between monocytes and T cells, and also functions as an inhibitor of cytolysis by the terminal C components C5b-9.	Polysaccharides	138-144	CD59 molecule (CD59 blood group)	Homo sapiens	4-8
1710238-3	1991	In the presence of the appropriate co-stimulators, mAb to one of the two epitopes on CD59 were capable of inducing both a rise in intracytoplasmic free Ca2+, inositol phosphate production, IL-2 production, and T cell proliferation.	Inositol Phosphates	158-176	CD59 molecule (CD59 blood group)	Homo sapiens	85-89
1710238-4	1991	Anti-CD59-induced inositol phosphate turnover and IL-2 production were dependent on co-expression of the CD3/TCR complex.	Inositol Phosphates	18-36	CD59 molecule (CD59 blood group)	Homo sapiens	5-9
2027756-3	1991	The results indicate two waves of crosslinking [rate constants (0.2-0.3) min-1 and (0.015-0.025) min-1] that correlate with changes in ultra violet absorbance and ethidium bromide dependent fluorescence intensity, previously interpreted in terms of two consecutive, local conformational rearrangements of platinum-DNA (Schaller, W., Reisner, H., and Holler, E. (1987) Biochemistry 26, 943-950).	Platinum	305-313	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
1706713-2	1991	The apparent Km (6.6 microM) and Vmax (99 nmol x min-1 x mg-1) observed with N omega-hydroxy-L-arginine were similar to those observed with L-arginine (Km = 2.3 microM; Vmax = 54 mumol x min-1 x mg-1).	N(omega)-hydroxyarginine	77-103	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
1706713-2	1991	The apparent Km (6.6 microM) and Vmax (99 nmol x min-1 x mg-1) observed with N omega-hydroxy-L-arginine were similar to those observed with L-arginine (Km = 2.3 microM; Vmax = 54 mumol x min-1 x mg-1).	N(omega)-hydroxyarginine	77-103	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
1706713-2	1991	The apparent Km (6.6 microM) and Vmax (99 nmol x min-1 x mg-1) observed with N omega-hydroxy-L-arginine were similar to those observed with L-arginine (Km = 2.3 microM; Vmax = 54 mumol x min-1 x mg-1).	Arginine	93-103	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
1706713-2	1991	The apparent Km (6.6 microM) and Vmax (99 nmol x min-1 x mg-1) observed with N omega-hydroxy-L-arginine were similar to those observed with L-arginine (Km = 2.3 microM; Vmax = 54 mumol x min-1 x mg-1).	Arginine	93-103	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
2027756-3	1991	The results indicate two waves of crosslinking [rate constants (0.2-0.3) min-1 and (0.015-0.025) min-1] that correlate with changes in ultra violet absorbance and ethidium bromide dependent fluorescence intensity, previously interpreted in terms of two consecutive, local conformational rearrangements of platinum-DNA (Schaller, W., Reisner, H., and Holler, E. (1987) Biochemistry 26, 943-950).	ultra violet	135-147	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
2027756-3	1991	The results indicate two waves of crosslinking [rate constants (0.2-0.3) min-1 and (0.015-0.025) min-1] that correlate with changes in ultra violet absorbance and ethidium bromide dependent fluorescence intensity, previously interpreted in terms of two consecutive, local conformational rearrangements of platinum-DNA (Schaller, W., Reisner, H., and Holler, E. (1987) Biochemistry 26, 943-950).	Ethidium	163-179	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
2027756-3	1991	The results indicate two waves of crosslinking [rate constants (0.2-0.3) min-1 and (0.015-0.025) min-1] that correlate with changes in ultra violet absorbance and ethidium bromide dependent fluorescence intensity, previously interpreted in terms of two consecutive, local conformational rearrangements of platinum-DNA (Schaller, W., Reisner, H., and Holler, E. (1987) Biochemistry 26, 943-950).	Ethidium	163-179	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
2027756-3	1991	The results indicate two waves of crosslinking [rate constants (0.2-0.3) min-1 and (0.015-0.025) min-1] that correlate with changes in ultra violet absorbance and ethidium bromide dependent fluorescence intensity, previously interpreted in terms of two consecutive, local conformational rearrangements of platinum-DNA (Schaller, W., Reisner, H., and Holler, E. (1987) Biochemistry 26, 943-950).	Platinum	305-313	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
1904753-4	1991	Gludopa had a clearance of 4.43 +/- 1.50 ml min-1 kg-1 and 4.92 ml min-1 kg-1 at the higher and lower doses, respectively.	gamma-glutamyl DOPA	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	44-60
1877354-4	1991	Resting O2 consumption increased by 15% from 279 +/- 7 ml min-1 (control) to 320 +/- 8 ml min-1 (stress, P less than 0.001).	Oxygen	8-10	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
1877354-4	1991	Resting O2 consumption increased by 15% from 279 +/- 7 ml min-1 (control) to 320 +/- 8 ml min-1 (stress, P less than 0.001).	Oxygen	8-10	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
1904753-4	1991	Gludopa had a clearance of 4.43 +/- 1.50 ml min-1 kg-1 and 4.92 ml min-1 kg-1 at the higher and lower doses, respectively.	gamma-glutamyl DOPA	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	44-54
2049245-9	1991	The renal clearance of codeine was 183 +/- 59 ml min-1 and was inversely correlated with urine pH (r = 0.81).	Codeine	23-30	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
2049245-11	1991	The renal clearance of codeine-6-glucuronide was 55 +/- 21 ml min-1, and was not correlated with urine pH.	codeine-6-glucuronide	23-44	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
2049245-21	1991	After the single dose, the partial clearance to morphine was 137 +/- 31 ml min-1 in the seven extensive metabolisers and 8 ml min-1 in the poor metaboliser; to norcodeine the values were 103 +/- 33 ml min-1 and 90 ml min-1; to codeine-6-glucuronide the values were 914 +/- 129 ml min-1 and 971 ml min-1; and intrinsic clearance was 1568 +/- 103 ml min-1 and 1450 ml min-1.	Morphine	48-56	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
2049253-7	1991	Seven randomized doses of PGE1 ranging from 0.01 to 1.3 micrograms kg-1 min-1 (2.83 to 364 pmol kg-1 min-1) were infused in an isotonic control saline solution.	Alprostadil	26-30	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
2049253-10	1991	Whatever the dose, PGE1 induced secretion of water, Na+, K+ and Cl- which was dose-dependent and saturable, with a mean Km of congruent to 6-8 pmol kg-1 min-1, suggesting that at the pharmacological doses used, enterocytes have a saturable membrane site similar to a single class of receptor for PGE1.	Alprostadil	19-23	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
2049253-10	1991	Whatever the dose, PGE1 induced secretion of water, Na+, K+ and Cl- which was dose-dependent and saturable, with a mean Km of congruent to 6-8 pmol kg-1 min-1, suggesting that at the pharmacological doses used, enterocytes have a saturable membrane site similar to a single class of receptor for PGE1.	Water	45-50	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
1851063-5	1991	Two litres of saline [0.9% (w/v) NaCl] were infused during the second hour of a 6 h infusion of aldosterone (3 pmol min-1 kg-1) or placebo in eight healthy young men.	Aldosterone	96-107	CD59 molecule (CD59 blood group)	Homo sapiens	116-126
2019988-5	1991	Upon intravenous infusion of dopamine for 3 hr at 5 micrograms kg-1 min-1, concentrations of free dopamine in plasma increased rapidly (280-970-fold), whereas conjugated dopamine only reached maximal values (14-19-fold increase) at 30 to 60 min after cessation of the infusion.	Dopamine	29-37	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
1672795-5	1991	Steady-state glucose disposal during hyperglycemia averaged (+/- SE) 33.8 +/- 3.2 mumol.kg fat-free mass-1.min-1, and approximately 70% of the glucose disposal was accounted for by skeletal muscle.	Glucose	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
2019988-5	1991	Upon intravenous infusion of dopamine for 3 hr at 5 micrograms kg-1 min-1, concentrations of free dopamine in plasma increased rapidly (280-970-fold), whereas conjugated dopamine only reached maximal values (14-19-fold increase) at 30 to 60 min after cessation of the infusion.	Dopamine	98-106	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
2019988-5	1991	Upon intravenous infusion of dopamine for 3 hr at 5 micrograms kg-1 min-1, concentrations of free dopamine in plasma increased rapidly (280-970-fold), whereas conjugated dopamine only reached maximal values (14-19-fold increase) at 30 to 60 min after cessation of the infusion.	Dopamine	98-106	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
2062549-9	1991	Pefloxacin had a sieving coefficient of 0.42 and a clearance of 6.8 ml min-1 when Qdi was nul.	Pefloxacin	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
2005122-4	1991	The purified enzyme has a Km of 110 microM, a Vmax of 34 mumol x l-1 x min-1, and a specific activity of 2.2 units/mg protein with N4-(beta-N-acetylglucosaminyl)-L-asparagine as substrate.	n4-(beta-n-acetylglucosaminyl)-l-asparagine	131-174	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
1900290-4	1991	The rap2 protein binds GTP and exhibits a low intrinsic GTPase activity (rate constant of 0.5 x 10(-2) min-1).	Guanosine Triphosphate	23-26	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
1995222-6	1991	Hypoxic and hypercapnic ventilatory responses were within predicted normal limits at 0.67 +/- 0.37 L/min-1 fall in SaO2-1 and 1.67 +/- 0.92 L/min-1 mm Hg PCO2(-1).	sao2	115-119	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
2054276-4	1991	The formation clearance of antipyrine to 4-hydroxyantipyrine was decreased significantly from 10.8 +/- 2.7 to 6.6 +/- 2.7 ml min-1 (P less than 0.05), while that to 3-hydroxymethylantipyrine and norantipyrine was not altered by diltiazem.	Antipyrine	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
2054276-4	1991	The formation clearance of antipyrine to 4-hydroxyantipyrine was decreased significantly from 10.8 +/- 2.7 to 6.6 +/- 2.7 ml min-1 (P less than 0.05), while that to 3-hydroxymethylantipyrine and norantipyrine was not altered by diltiazem.	4-hydroxyantipyrine	41-60	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
1850682-4	1991	Increases in whole-body noradrenaline spillover to arterial plasma were larger (from 282 +/- 40 ng min-1 m-2 to 358 +/- 41 ng min-1 m-2, P less than 0.01) and there was a trend towards an increase in whole-body noradrenaline clearance.	Norepinephrine	24-37	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
1850682-4	1991	Increases in whole-body noradrenaline spillover to arterial plasma were larger (from 282 +/- 40 ng min-1 m-2 to 358 +/- 41 ng min-1 m-2, P less than 0.01) and there was a trend towards an increase in whole-body noradrenaline clearance.	Norepinephrine	24-37	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
1850686-9	1991	At rest in the supine position the rate of noradrenaline re-uptake was 474 +/- 122 pmol min-1 kg-1, 9.5-fold higher than the rate of spillover of noradrenaline into plasma (49.6 +/- 6.4 pmol min-1 kg-1).	Norepinephrine	43-56	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
1850686-9	1991	At rest in the supine position the rate of noradrenaline re-uptake was 474 +/- 122 pmol min-1 kg-1, 9.5-fold higher than the rate of spillover of noradrenaline into plasma (49.6 +/- 6.4 pmol min-1 kg-1).	Norepinephrine	43-56	CD59 molecule (CD59 blood group)	Homo sapiens	88-98
2023113-5	1991	Beta-Adrenergic receptor activation was blocked by the infusion of dl-propranolol (17 micrograms kg-1 min-1).	Propranolol	67-81	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
1874208-8	1991	Therefore, the infusion rate of PGE1 during CPB should be 30 ng kg-1 min-1 or less in order to avoid severe hypotension.	Alprostadil	32-36	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
1997515-5	1991	In all cases glucagon was replaced (58 ng min-1).	Glucagon	13-21	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
1902517-13	1991	This corresponded to a glycogen resynthesis rate from lactate of 0.17-0.34 and 0.002 mmol glucosyl units min-1 (kg wet wt)-1 for the first 10 and last 50 min of recovery, respectively.	Glycogen	23-31	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
1902517-13	1991	This corresponded to a glycogen resynthesis rate from lactate of 0.17-0.34 and 0.002 mmol glucosyl units min-1 (kg wet wt)-1 for the first 10 and last 50 min of recovery, respectively.	glucosyl	90-98	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
1875801-1	1991	There is now substantive evidence that the provision of exogenous carbohydrate at high rates (1-2 g. min-1) can enhance performance during prolonged exercise.	Carbohydrates	66-78	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
1847721-4	1991	Lisinopril reduced albumin excretion from 1343 +/- 337 micrograms min-1 to 879 +/- 299 micrograms min-1 (P less than 0.01), whereas nifedipine was without effect, 1436 +/- 336 micrograms min-1 vs. 1319 +/- 342 micrograms min-1.	Lisinopril	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
2020093-11	1991	Nevertheless two patients in each group required oxygen 2 liter.min-1 via a nasal catheter.	Oxygen	49-55	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
1847721-4	1991	Lisinopril reduced albumin excretion from 1343 +/- 337 micrograms min-1 to 879 +/- 299 micrograms min-1 (P less than 0.01), whereas nifedipine was without effect, 1436 +/- 336 micrograms min-1 vs. 1319 +/- 342 micrograms min-1.	Lisinopril	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
1847721-4	1991	Lisinopril reduced albumin excretion from 1343 +/- 337 micrograms min-1 to 879 +/- 299 micrograms min-1 (P less than 0.01), whereas nifedipine was without effect, 1436 +/- 336 micrograms min-1 vs. 1319 +/- 342 micrograms min-1.	Lisinopril	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
1847721-4	1991	Lisinopril reduced albumin excretion from 1343 +/- 337 micrograms min-1 to 879 +/- 299 micrograms min-1 (P less than 0.01), whereas nifedipine was without effect, 1436 +/- 336 micrograms min-1 vs. 1319 +/- 342 micrograms min-1.	Lisinopril	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
1844104-2	1991	The measurement of transcutaneous PtcO2 in eight normal adults prove a comparable efficacy of 50 l.min-1 O2 through facial "small mask" (61.5 kPa; 463 mmHg) and 20 l.min-1 O2 through head tent (65.1 kPa; 490 mmHg).	Oxygen	105-107	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
2063982-9	1991	Only one patient with cardiac disease needed oxygen adjonction (2 l.min-1) to raise his SaO2 level above 95%.	Oxygen	45-51	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
2008972-4	1991	Dopamine was then added, up to a dose of 15-20 micrograms.kg-1.min-1, in an attempt to improve coronary and renal blood flows.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
2063982-9	1991	Only one patient with cardiac disease needed oxygen adjonction (2 l.min-1) to raise his SaO2 level above 95%.	sao2	88-92	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
1984343-3	1991	Results showed that basal leucine carbon flux was greater (P less than 0.05) in UB Ob and LB Ob women than in Non Ob women (2.96 +/- 0.08 vs 3.14 +/- 0.16 vs 2.68 +/- 0.08 mumol.kg lean body mass-1.min-1, respectively; mean +/- SEM).	Carbon	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	198-203
1676248-9	1991	Cardiovascular collapse was treated with dobutamine (10 micrograms.kg-1.min-1).	Dobutamine	41-51	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
1785702-9	1991	Placebo consisted in a two hour infusion of 0.25 ml.min-1 normal saline.	Sodium Chloride	65-71	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
1910671-2	1991	Kinetic analysis of the time course of binding of FITC-neurotoxins to the nAChR-coated fiber gave association rate constants (k+1) of 8.4 x 10(6) M-1 min-1 for FITC-alpha-BGT, 6.0 x 10(6) M-1 min-1 for FITC-alpha-NT and 1.4 x 10(6) M-1 min-1 for FITC-alpha-CNTX.	Fluorescein-5-isothiocyanate	50-54	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
1910671-2	1991	Kinetic analysis of the time course of binding of FITC-neurotoxins to the nAChR-coated fiber gave association rate constants (k+1) of 8.4 x 10(6) M-1 min-1 for FITC-alpha-BGT, 6.0 x 10(6) M-1 min-1 for FITC-alpha-NT and 1.4 x 10(6) M-1 min-1 for FITC-alpha-CNTX.	Fluorescein-5-isothiocyanate	50-54	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
1910671-2	1991	Kinetic analysis of the time course of binding of FITC-neurotoxins to the nAChR-coated fiber gave association rate constants (k+1) of 8.4 x 10(6) M-1 min-1 for FITC-alpha-BGT, 6.0 x 10(6) M-1 min-1 for FITC-alpha-NT and 1.4 x 10(6) M-1 min-1 for FITC-alpha-CNTX.	Fluorescein-5-isothiocyanate	50-54	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
1910671-2	1991	Kinetic analysis of the time course of binding of FITC-neurotoxins to the nAChR-coated fiber gave association rate constants (k+1) of 8.4 x 10(6) M-1 min-1 for FITC-alpha-BGT, 6.0 x 10(6) M-1 min-1 for FITC-alpha-NT and 1.4 x 10(6) M-1 min-1 for FITC-alpha-CNTX.	Fluorescein-5-isothiocyanate	160-164	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
1910671-2	1991	Kinetic analysis of the time course of binding of FITC-neurotoxins to the nAChR-coated fiber gave association rate constants (k+1) of 8.4 x 10(6) M-1 min-1 for FITC-alpha-BGT, 6.0 x 10(6) M-1 min-1 for FITC-alpha-NT and 1.4 x 10(6) M-1 min-1 for FITC-alpha-CNTX.	Fluorescein-5-isothiocyanate	160-164	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
1910671-2	1991	Kinetic analysis of the time course of binding of FITC-neurotoxins to the nAChR-coated fiber gave association rate constants (k+1) of 8.4 x 10(6) M-1 min-1 for FITC-alpha-BGT, 6.0 x 10(6) M-1 min-1 for FITC-alpha-NT and 1.4 x 10(6) M-1 min-1 for FITC-alpha-CNTX.	Fluorescein-5-isothiocyanate	160-164	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
1910671-2	1991	Kinetic analysis of the time course of binding of FITC-neurotoxins to the nAChR-coated fiber gave association rate constants (k+1) of 8.4 x 10(6) M-1 min-1 for FITC-alpha-BGT, 6.0 x 10(6) M-1 min-1 for FITC-alpha-NT and 1.4 x 10(6) M-1 min-1 for FITC-alpha-CNTX.	fitc-alpha-nt	202-215	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
1910671-2	1991	Kinetic analysis of the time course of binding of FITC-neurotoxins to the nAChR-coated fiber gave association rate constants (k+1) of 8.4 x 10(6) M-1 min-1 for FITC-alpha-BGT, 6.0 x 10(6) M-1 min-1 for FITC-alpha-NT and 1.4 x 10(6) M-1 min-1 for FITC-alpha-CNTX.	fitc-alpha-cntx	246-261	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
1910671-4	1991	4.8 x 10(-2) min-1 and 8.0 x 10(-1) min-1 for FITC-alpha-BGT.	Fluorescein-5-isothiocyanate	46-50	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
1997059-4	1991	The mean (SD) total clearance of methohexitone was 16.3 (4.2) ml min-1 kg-1, which is greater than that for volunteers or normal surgical patients.	Methohexital	33-46	CD59 molecule (CD59 blood group)	Homo sapiens	65-75
1989577-6	1991	The bile acid released 90% of the Ca2+ pools, with rate constants of about 5 min-1 and half-maximal effects at 15-30 microM.	Bile Acids and Salts	4-13	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
2015160-4	1991	of oral plasma clearance, volume of distribution and elimination half-life for R(-)-flurbiprofen were 0.075 (+/- 0.066) l min-1, 12.47 (+/- 5.79) l and 138 (+/- 61) min, respectively.	Flurbiprofen	79-96	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
2015160-6	1991	of oral plasma clearance, volume of distribution and elimination half-life for S(+)-flurbiprofen were 0.057 (+/- 0.035) l min-1, 12.81 (+/- 4.43) l and 155 (+/- 49) min, respectively.	Flurbiprofen	80-96	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
2015174-11	1991	When ifosfamide 5 g m-2 was given as a 24 h infusion, the decay of the plasma ifosfamide concentration was monoexponential, the median (range) t1/2,z was 4.5 (3.4-6.1), the median volume of distribution was 563 (292-818) ml kg-1 and the median clearance was 79 (59-116) ml min-1.	Ifosfamide	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	273-278
2019080-2	1991	For COPD patients the maximum oxygen uptake (VOmax) was 19.6 +/- 3.8 ml kg-1 min-1 (+/- SD), and percentage of forced expired volume at 1 s (% FEV1) was 47.8 +/- 10.4%.	Oxygen	30-36	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
1988236-3	1991	Imipramine demethylation clearance was 0.74 L.min-1 (mean; range, 0.31-1.24) in poor metabolizers of mephenytoin compared with 1.43 L.min-1 (mean; range, 0.61-3.81) in extensive metabolizers of mephenytoin (p = 0.01, Mann-Whitney U test).	Imipramine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
1988236-3	1991	Imipramine demethylation clearance was 0.74 L.min-1 (mean; range, 0.31-1.24) in poor metabolizers of mephenytoin compared with 1.43 L.min-1 (mean; range, 0.61-3.81) in extensive metabolizers of mephenytoin (p = 0.01, Mann-Whitney U test).	Imipramine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
1988236-3	1991	Imipramine demethylation clearance was 0.74 L.min-1 (mean; range, 0.31-1.24) in poor metabolizers of mephenytoin compared with 1.43 L.min-1 (mean; range, 0.61-3.81) in extensive metabolizers of mephenytoin (p = 0.01, Mann-Whitney U test).	Mephenytoin	101-112	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
1874239-5	1991	Heart rate (fc) was significantly lower in T than in U before handgrip exercise, and showed smaller increases (P less than 0.01) at the point of exhaustion: 89 vs 106 beats.min-1 for RH, 93 vs 100 beats.min-1 for LH and 92 vs 108 beats.min-1 for RLH.	Luteinizing Hormone	213-215	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
1874239-5	1991	Heart rate (fc) was significantly lower in T than in U before handgrip exercise, and showed smaller increases (P less than 0.01) at the point of exhaustion: 89 vs 106 beats.min-1 for RH, 93 vs 100 beats.min-1 for LH and 92 vs 108 beats.min-1 for RLH.	Luteinizing Hormone	213-215	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
1874239-5	1991	Heart rate (fc) was significantly lower in T than in U before handgrip exercise, and showed smaller increases (P less than 0.01) at the point of exhaustion: 89 vs 106 beats.min-1 for RH, 93 vs 100 beats.min-1 for LH and 92 vs 108 beats.min-1 for RLH.	rlh	246-249	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
1874239-5	1991	Heart rate (fc) was significantly lower in T than in U before handgrip exercise, and showed smaller increases (P less than 0.01) at the point of exhaustion: 89 vs 106 beats.min-1 for RH, 93 vs 100 beats.min-1 for LH and 92 vs 108 beats.min-1 for RLH.	rlh	246-249	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
2044538-5	1991	The first-order rate constant (min-1) for decline of arterialised venous blood lactate concentration after the intense exercise was 0.027 (0.003) in PR, 0.058 (0.025) in SL, 0.034 (0.002) in OL, and in RA was 0.028 (0.002) [mean (SEM), n = 6 subjects].	Lactic Acid	79-86	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
1679390-7	1991	Heart Rate (hR) increased significantly from 67 to 72 beats.min-1 in those on cadralazine and from 65 to 69 beats.min-1 on prazosin.	cadralazine	78-89	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
1773815-5	1991	These changes were associated with a small increase in the mean oxygen consumption over all levels of rest and exercise (0.86 l min-1 vs 0.82 l min-1, P less than 0.001) and a corresponding increase in mean energy expenditure (294 W vs 283 W, P less than 0.05).	Oxygen	64-70	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
1773815-5	1991	These changes were associated with a small increase in the mean oxygen consumption over all levels of rest and exercise (0.86 l min-1 vs 0.82 l min-1, P less than 0.001) and a corresponding increase in mean energy expenditure (294 W vs 283 W, P less than 0.05).	Oxygen	64-70	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
1815970-6	1991	In uraemic patients, Cmax and tmax were slightly increased and t1/2 was increased to 12-14 h in patients with an endogenous creatinine clearance below 20 ml.min-1.	Creatinine	124-134	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
1820892-6	1991	After intravenous administration, the MRT was on average 2 hours and the mean CLS was about 900 ml.min-1.	Chlorine	78-81	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
1884731-2	1991	Flosequinan improved cardiac output by a maximum of 1.59 l.min-1, it reduced pulmonary capillary wedge pressure by 11.9 mm Hg and it also caused a reduction in right atrial pressure by a maximum of 7.2 mm Hg.	flosequinan	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
1906003-3	1991	The apparent oral clearances of R- and S-flecainide were lower in PMs (R 313 ml.min-1; S 379 ml.min-1) than in EMs (R 783 ml.min-1; S 828 ml.min-1).	r- and s-flecainide	32-51	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
1906003-3	1991	The apparent oral clearances of R- and S-flecainide were lower in PMs (R 313 ml.min-1; S 379 ml.min-1) than in EMs (R 783 ml.min-1; S 828 ml.min-1).	r- and s-flecainide	32-51	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
1906003-3	1991	The apparent oral clearances of R- and S-flecainide were lower in PMs (R 313 ml.min-1; S 379 ml.min-1) than in EMs (R 783 ml.min-1; S 828 ml.min-1).	r- and s-flecainide	32-51	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
1906003-3	1991	The apparent oral clearances of R- and S-flecainide were lower in PMs (R 313 ml.min-1; S 379 ml.min-1) than in EMs (R 783 ml.min-1; S 828 ml.min-1).	r- and s-flecainide	32-51	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
1906003-6	1991	The partial clearance to the two major metabolites meta-O-dealkylated flecainide (MODF) and the meta-O-dealkylated lactam of flecainide (MODLF) was significantly lower in poor (62 ml.min-1) than extensive (267 ml.min-1) metabolisers.	Flecainide	125-135	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
2050175-2	1991	After IV administration the plasma lisuride fell in two phases with half-lives of 14 min and 1.5 h. Total clearance was 13 ml.min-1.kg-1.	Lisuride	35-43	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
2050182-2	1991	There was a high correlation between the measured and predicted creatinine clearance as shown by the regression equation: measured creatinine clearance = 0.84 predicted creatinine clearance +4.5 ml.min-1 (r2 = 0.74).	Creatinine	64-74	CD59 molecule (CD59 blood group)	Homo sapiens	198-203
2050182-2	1991	There was a high correlation between the measured and predicted creatinine clearance as shown by the regression equation: measured creatinine clearance = 0.84 predicted creatinine clearance +4.5 ml.min-1 (r2 = 0.74).	Creatinine	131-141	CD59 molecule (CD59 blood group)	Homo sapiens	198-203
2050182-2	1991	There was a high correlation between the measured and predicted creatinine clearance as shown by the regression equation: measured creatinine clearance = 0.84 predicted creatinine clearance +4.5 ml.min-1 (r2 = 0.74).	Creatinine	131-141	CD59 molecule (CD59 blood group)	Homo sapiens	198-203
2060561-10	1991	Chronotropic responses to salbutamol were greater in the elderly: 39 versus 24 beats.min-1.	Albuterol	26-36	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
2065697-3	1991	During intravenous infusion of adenosine (Maximum dose per min: mean 130 micrograms kg-1) mean minute ventilation increased from 5.5 to 10.9 l min-1 while mean plasma adenosine concentration in the aortic arch increased from 0.07 to 1.2 microM.	Adenosine	31-40	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
1665467-2	1991	We define a standard independent unit (SIU) of heparin as that amount that, in plasma containing 1 mumol of ATIII, raises the (pseudo-)first-order breakdown constant of factor Xa by 1 min-1.	Heparin	47-54	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
1743765-9	1991	The calculated (from HR measurements) average oxygen consumption (VO2) varied from 0.9 to 1.9 l min-1, which corresponded to 27%-60% of the maximal value.	Oxygen	46-52	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
1985095-3	1991	RESULTS: Adipose tissue palmitate release was greater from forearm than whole body (5.97 +/- 0.75 vs. 3.84 +/- 0.34 mumol.kg fat-1.min-1, respectively, P less than 0.005, n = 22 subjects).	Palmitates	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
1787554-8	1991	The average increase in oxygen uptake above pre-exercise levels during the sprint test was greater for endurance-trained athletes than for the games players (ET vs GP: 35.0 +/- 2.2 vs 29.6 +/- 3.0 ml kg-1 min-1, P less than 0.05), corresponding to an average oxygen uptake per sprint (6-s sprint and 24 s of subsequent recovery) of 67.5 +/- 2.9% and 63.0 +/- 4.5% VO2 max respectively (N.S.).	Oxygen	24-30	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
2041381-4	1991	Sixteen patients were included and 55 treatment courses were given at different dose levels of chemotherapy; verapamil was given by continuous infusion of 0.003 mg kg-1 min-1 for 48 h. Overall, cardiac toxicity was low but a potentiation of neurotoxicity and hematotoxicity was observed.	Verapamil	109-118	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2003045-5	1991	Following sedation with triclofos, mean RR rose by 1.9 breaths min-1 (95% confidence intervals [Cl] of the mean difference: 0.13-3.7 min-1).	triclofos	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
2003045-5	1991	Following sedation with triclofos, mean RR rose by 1.9 breaths min-1 (95% confidence intervals [Cl] of the mean difference: 0.13-3.7 min-1).	triclofos	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
1833898-6	1991	Dobutamine was administered in a dose of 4-7 micrograms.kg-1.min-1 over the same period.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
2148516-9	1990	Co2+.ATP can be used as a substrate by this enzyme with Vmax of 2.4 +/- 0.2 mumol ATP hydrolyzed min-1 (mg protein)-1 at 20-22 degrees C and pH 8.0, and with a K0.5 of 0.4-0.5 mM.	Adenosine Triphosphate	5-8	CD59 molecule (CD59 blood group)	Homo sapiens	97-117
2148516-9	1990	Co2+.ATP can be used as a substrate by this enzyme with Vmax of 2.4 +/- 0.2 mumol ATP hydrolyzed min-1 (mg protein)-1 at 20-22 degrees C and pH 8.0, and with a K0.5 of 0.4-0.5 mM.	Adenosine Triphosphate	82-85	CD59 molecule (CD59 blood group)	Homo sapiens	97-117
2248392-1	1990	Using implanted pulsed Doppler microprobes sutured on saphenous bypass grafts in ten patients we studied, 6 h after cardiac surgery, the effects of 5 and 10 micrograms.kg-1.min-1 of dobutamine on mean (Qm), systolic (Qs), and diastolic (Qd) coronary bypass graft flows, as well as on coronary systolic (integral of Qs) and diastolic (integral of Qd) blood volumes entering the myocardium per cardiac beat.	Dobutamine	182-192	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
2265045-6	1990	The clearance of propofol was rapid (mean 1.6 (0.24) litre min-1).	Propofol	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
2288837-2	1990	The mean plasma clearance of morphine was 29 ml min-1 kg-1 and the plasma ratios of morphine-6-glucuronide to morphine were similar to those previously reported in children.	Morphine	29-37	CD59 molecule (CD59 blood group)	Homo sapiens	48-58
2288837-3	1990	The mean plasma clearance of ketamine was 32 ml min-1 kg-1 which is greater than that previously reported in older children and adults.	Ketamine	29-37	CD59 molecule (CD59 blood group)	Homo sapiens	48-58
2176947-7	1990	Energy expenditure calculated from the oxygen consumption and the respiratory exchange ratio was higher than control values during infusion of dopamine (P less than 0.001, analysis of variance) specifically at a rate of 10 micrograms min-1 kg-1 (P less than 0.05) when it was 14% higher, but not at a rate 2 of or 5 micrograms min-1 kg-1.	Dopamine	143-151	CD59 molecule (CD59 blood group)	Homo sapiens	234-244
2176947-7	1990	Energy expenditure calculated from the oxygen consumption and the respiratory exchange ratio was higher than control values during infusion of dopamine (P less than 0.001, analysis of variance) specifically at a rate of 10 micrograms min-1 kg-1 (P less than 0.05) when it was 14% higher, but not at a rate 2 of or 5 micrograms min-1 kg-1.	Dopamine	143-151	CD59 molecule (CD59 blood group)	Homo sapiens	327-337
2176947-8	1990	The plasma noradrenaline concentration was 74 and 230% and the blood glucose concentration was 21 and 36% higher than control values at 5 and 10 micrograms of dopamine min-1 kg-1, respectively (P less than 0.01).	Glucose	69-76	CD59 molecule (CD59 blood group)	Homo sapiens	168-178
2176947-8	1990	The plasma noradrenaline concentration was 74 and 230% and the blood glucose concentration was 21 and 36% higher than control values at 5 and 10 micrograms of dopamine min-1 kg-1, respectively (P less than 0.01).	Dopamine	159-167	CD59 molecule (CD59 blood group)	Homo sapiens	168-178
2176947-9	1990	At 10 micrograms of dopamine min-1 kg-1 the plasma free fatty acid concentration was 70% and the plasma glycerol concentration was 80% higher than during the control infusion (P less than 0.01).	Dopamine	20-28	CD59 molecule (CD59 blood group)	Homo sapiens	29-39
2176947-9	1990	At 10 micrograms of dopamine min-1 kg-1 the plasma free fatty acid concentration was 70% and the plasma glycerol concentration was 80% higher than during the control infusion (P less than 0.01).	Fatty Acids, Nonesterified	51-66	CD59 molecule (CD59 blood group)	Homo sapiens	29-39
2176947-9	1990	At 10 micrograms of dopamine min-1 kg-1 the plasma free fatty acid concentration was 70% and the plasma glycerol concentration was 80% higher than during the control infusion (P less than 0.01).	Glycerol	104-112	CD59 molecule (CD59 blood group)	Homo sapiens	29-39
2176947-11	1990	The plasma adrenaline concentration rose significantly (P less than 0.01), but only transiently, during dopamine infusion at a rate of 2 micrograms min-1 kg-1.	Epinephrine	11-21	CD59 molecule (CD59 blood group)	Homo sapiens	148-158
2176947-11	1990	The plasma adrenaline concentration rose significantly (P less than 0.01), but only transiently, during dopamine infusion at a rate of 2 micrograms min-1 kg-1.	Dopamine	104-112	CD59 molecule (CD59 blood group)	Homo sapiens	148-158
2176947-14	1990	It increases the blood glucose concentration and the circulating noradrenaline level at an infusion rate of 5 micrograms min-1 kg-1.	Glucose	23-30	CD59 molecule (CD59 blood group)	Homo sapiens	121-131
2176947-14	1990	It increases the blood glucose concentration and the circulating noradrenaline level at an infusion rate of 5 micrograms min-1 kg-1.	Norepinephrine	65-78	CD59 molecule (CD59 blood group)	Homo sapiens	121-131
2249372-4	1990	Morphine terminal half-life was 92 +/- 9 minutes, total body clearance was 1260 ml.min-1, and the hepatic extraction ratio was 0.65 +/- 0.11.	Morphine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
2149683-5	1990	Nicotinic acid decreased plasma NEFA concentration from 0.54 +/- 0.15 to 0.23 +/- 0.08 mmol l-1, but plasma glucose (15.0 +/- 1.0 vs 15.5 +/- 1.4 mmol l-1), Ra (0.74 +/- 0.07 vs 0.68 +/- 0.07 mmol m-2 min-1), and Rd (0.73 +/- 0.07 vs 0.68 +/- 0.07 mmol m-2 min-1) were unchanged.	Niacin	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	201-206
2149683-5	1990	Nicotinic acid decreased plasma NEFA concentration from 0.54 +/- 0.15 to 0.23 +/- 0.08 mmol l-1, but plasma glucose (15.0 +/- 1.0 vs 15.5 +/- 1.4 mmol l-1), Ra (0.74 +/- 0.07 vs 0.68 +/- 0.07 mmol m-2 min-1), and Rd (0.73 +/- 0.07 vs 0.68 +/- 0.07 mmol m-2 min-1) were unchanged.	Niacin	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	257-262
1964125-6	1990	PGE2 excretion rate increased after furosemide in the cirrhotic patients (0.29 to 0.66 pmol min-1; P less than 0.01) but not in the controls (0.31 to 0.38 pmol min-1).	Dinoprostone	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
1964125-6	1990	PGE2 excretion rate increased after furosemide in the cirrhotic patients (0.29 to 0.66 pmol min-1; P less than 0.01) but not in the controls (0.31 to 0.38 pmol min-1).	Dinoprostone	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
1679390-7	1991	Heart Rate (hR) increased significantly from 67 to 72 beats.min-1 in those on cadralazine and from 65 to 69 beats.min-1 on prazosin.	Prazosin	123-131	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
1685992-7	1991	The dose required to increase systolic blood pressure by 20 mm Hg increased from 156.9 micrograms.min-1 before to 685 micrograms.min-1 during urapidil; Dose ratio from individual values of 4.58.	urapidil	142-150	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
2129229-4	1990	Placental clearance for mannitol was 8.7 +/- 1.1 ml min-1 (mean +/- S.E.M.	Mannitol	24-32	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
2129130-3	1990	In this study PICO2 was measured to know the drug"s functioning time and CO2 elimination from the model lung fixed at 200 or 300 ml.min-1.	pico2	14-19	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
2129130-3	1990	In this study PICO2 was measured to know the drug"s functioning time and CO2 elimination from the model lung fixed at 200 or 300 ml.min-1.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	16-19	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
2240206-2	1990	Forearm alanine and lactate fractional extraction averaged 37 +/- 3 and 27 +/- 2%, respectively; muscle alanine release (2.94 +/- 0.27 mumol.kg body wt-1.min-1) accounted for approximately 70% of its systemic appearance (4.18 +/- 0.31 mumol.kg body wt-1.min-1); muscle lactate release (5.51 +/- 0.42 mumol.kg body wt-1.min-1) accounted for approximately 40% of its systemic appearance (12.66 +/- 0.77 mumol.kg body wt-1.min-1); muscle alanine and lactate uptake (1.60 +/- 0.7 and 3.29 +/- 0.36 mumol.kg body wt-1.min-1, respectively) accounted for approximately 30% of their overall disappearance from plasma, whereas alanine and lactate incorporation into plasma glucose (1.83 +/- 0.20 and 4.24 +/- 0.44 mumol.kg body wt-1.min-1, respectively) accounted for approximately 50% of their disappearance from plasma.	Alanine	104-111	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
2240206-2	1990	Forearm alanine and lactate fractional extraction averaged 37 +/- 3 and 27 +/- 2%, respectively; muscle alanine release (2.94 +/- 0.27 mumol.kg body wt-1.min-1) accounted for approximately 70% of its systemic appearance (4.18 +/- 0.31 mumol.kg body wt-1.min-1); muscle lactate release (5.51 +/- 0.42 mumol.kg body wt-1.min-1) accounted for approximately 40% of its systemic appearance (12.66 +/- 0.77 mumol.kg body wt-1.min-1); muscle alanine and lactate uptake (1.60 +/- 0.7 and 3.29 +/- 0.36 mumol.kg body wt-1.min-1, respectively) accounted for approximately 30% of their overall disappearance from plasma, whereas alanine and lactate incorporation into plasma glucose (1.83 +/- 0.20 and 4.24 +/- 0.44 mumol.kg body wt-1.min-1, respectively) accounted for approximately 50% of their disappearance from plasma.	Alanine	104-111	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
2240206-2	1990	Forearm alanine and lactate fractional extraction averaged 37 +/- 3 and 27 +/- 2%, respectively; muscle alanine release (2.94 +/- 0.27 mumol.kg body wt-1.min-1) accounted for approximately 70% of its systemic appearance (4.18 +/- 0.31 mumol.kg body wt-1.min-1); muscle lactate release (5.51 +/- 0.42 mumol.kg body wt-1.min-1) accounted for approximately 40% of its systemic appearance (12.66 +/- 0.77 mumol.kg body wt-1.min-1); muscle alanine and lactate uptake (1.60 +/- 0.7 and 3.29 +/- 0.36 mumol.kg body wt-1.min-1, respectively) accounted for approximately 30% of their overall disappearance from plasma, whereas alanine and lactate incorporation into plasma glucose (1.83 +/- 0.20 and 4.24 +/- 0.44 mumol.kg body wt-1.min-1, respectively) accounted for approximately 50% of their disappearance from plasma.	Alanine	104-111	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
2221411-3	1990	Twenty children received 3 mg.kg-1.min-1 of propofol as a loading dose followed by a maintenance dose of 0.1 mg.kg-1.min-1 (+/- 10%).	Propofol	44-52	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
2248845-6	1990	The clearances of atracurium, estimated by the constant infusion rate required to maintain the steady state plasma concentration, at 50-60 min and during estimation of Cpss90 were 3.8 (1.0) and 3.9 (1.1) ml kg-1 min-1 (ns), respectively.	Atracurium	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	212-217
2271371-6	1990	A pharmacokinetic analysis revealed a significant decrease in the median (range) elimination half-life of ifosfamide from 7.2 (2.8-14.2) h on day 1 to 4.6 (2.3-7.7) h on day 5 (P less than 0.001, Wilcoxon"s test) with a concomitant significant increase in the median (range) clearance from 66 (31-148) ml min-1 on day 1 to 115 (52-381) ml min-1 on day 5 (P less than 0.001).	Ifosfamide	106-116	CD59 molecule (CD59 blood group)	Homo sapiens	305-310
2271371-6	1990	A pharmacokinetic analysis revealed a significant decrease in the median (range) elimination half-life of ifosfamide from 7.2 (2.8-14.2) h on day 1 to 4.6 (2.3-7.7) h on day 5 (P less than 0.001, Wilcoxon"s test) with a concomitant significant increase in the median (range) clearance from 66 (31-148) ml min-1 on day 1 to 115 (52-381) ml min-1 on day 5 (P less than 0.001).	Ifosfamide	106-116	CD59 molecule (CD59 blood group)	Homo sapiens	339-344
2271371-12	1990	The median (range) renal clearance of ifosfamide on day 1 was 6.8 (1.3-16.2) ml min-1 compared with 5.7 (1.3-15.3) ml min-1 on day 5.	Ifosfamide	38-48	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
2271371-14	1990	The median (range) metabolic clearance of ifosfamide in these five patients on day 1 was 78.6 (39.9-141.2) ml min-1 and 132.6 (54.6-149.5) ml min-1 on day 5.	Ifosfamide	42-52	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
2271371-14	1990	The median (range) metabolic clearance of ifosfamide in these five patients on day 1 was 78.6 (39.9-141.2) ml min-1 and 132.6 (54.6-149.5) ml min-1 on day 5.	Ifosfamide	42-52	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
2271373-4	1990	The median total and unbound clearance of oxazepam increased significantly during the study period from 0.78 ml min-1 kg-1 (0.40-1.25) to 1.22 ml min-1 kg-1 (0.66-1.94) and from 9.3 ml min-1 kg-1 (5.2-14.2) to 15.9 ml min-1 kg-1 (7.8-21.8), respectively (P less than 0.01).	Oxazepam	42-50	CD59 molecule (CD59 blood group)	Homo sapiens	112-122
2271373-4	1990	The median total and unbound clearance of oxazepam increased significantly during the study period from 0.78 ml min-1 kg-1 (0.40-1.25) to 1.22 ml min-1 kg-1 (0.66-1.94) and from 9.3 ml min-1 kg-1 (5.2-14.2) to 15.9 ml min-1 kg-1 (7.8-21.8), respectively (P less than 0.01).	Oxazepam	42-50	CD59 molecule (CD59 blood group)	Homo sapiens	146-156
2271373-4	1990	The median total and unbound clearance of oxazepam increased significantly during the study period from 0.78 ml min-1 kg-1 (0.40-1.25) to 1.22 ml min-1 kg-1 (0.66-1.94) and from 9.3 ml min-1 kg-1 (5.2-14.2) to 15.9 ml min-1 kg-1 (7.8-21.8), respectively (P less than 0.01).	Oxazepam	42-50	CD59 molecule (CD59 blood group)	Homo sapiens	146-156
2271373-4	1990	The median total and unbound clearance of oxazepam increased significantly during the study period from 0.78 ml min-1 kg-1 (0.40-1.25) to 1.22 ml min-1 kg-1 (0.66-1.94) and from 9.3 ml min-1 kg-1 (5.2-14.2) to 15.9 ml min-1 kg-1 (7.8-21.8), respectively (P less than 0.01).	Oxazepam	42-50	CD59 molecule (CD59 blood group)	Homo sapiens	146-156
2271373-10	1990	The median (range) clearance of paracetamol under hypothyroid conditions was 3.12 ml min-1 kg-1 (1.64-4.40) and 4.70 ml min-1 kg-1 (3.18-5.70) following replacement therapy (P less than 0.01).	Acetaminophen	32-43	CD59 molecule (CD59 blood group)	Homo sapiens	85-95
2271373-11	1990	This increase was associated with a comparable increase in the partial clearance to the glucuronide metabolite: 1.86 ml min-1 kg-1 to 2.70 ml min-1 kg-1.	Glucuronides	88-99	CD59 molecule (CD59 blood group)	Homo sapiens	120-130
2271373-11	1990	This increase was associated with a comparable increase in the partial clearance to the glucuronide metabolite: 1.86 ml min-1 kg-1 to 2.70 ml min-1 kg-1.	Glucuronides	88-99	CD59 molecule (CD59 blood group)	Homo sapiens	142-152
2083480-5	1990	Net splanchnic glucose balance switched from a positive value (i.e. net uptake) of 5.06 +/- 2.56 mumol min-1 kg-1 with intravenous glucose alone (0-60 min) to a negative one (i.e. net output) of 12.50 +/- 2.44 mumol min-1 kg-1 during 4 h (60-300 min) of intravenous + oral glucose.	Glucose	15-22	CD59 molecule (CD59 blood group)	Homo sapiens	103-113
2083480-5	1990	Net splanchnic glucose balance switched from a positive value (i.e. net uptake) of 5.06 +/- 2.56 mumol min-1 kg-1 with intravenous glucose alone (0-60 min) to a negative one (i.e. net output) of 12.50 +/- 2.44 mumol min-1 kg-1 during 4 h (60-300 min) of intravenous + oral glucose.	Glucose	15-22	CD59 molecule (CD59 blood group)	Homo sapiens	216-226
2083480-6	1990	The mean rate of splanchnic glucose uptake was estimated to be 6.39 +/- 4.67 mumol min-1 kg-1 with intravenous glucose alone, and 8.83 +/- 4.28 mumol min-1 kg-1 with intravenous + oral glucose.	Glucose	28-35	CD59 molecule (CD59 blood group)	Homo sapiens	83-93
2242615-9	1990	These results indicate that HRF20 attaches to keratinocytes and blood vessels via phosphatidylinositol, regulating the formation of membrane attack complexes of homologous complement on the cell membrane.	Phosphatidylinositols	82-102	CD59 molecule (CD59 blood group)	Homo sapiens	28-33
2076800-6	1990	Negative endogenous glucose production rates were observed both at 90-120 min (-8.8 +/- 1.6 mumol.kg-1min-1) and at 210-240 min (-8.5 +/- 1.4 mumol.kg-1min-1) implying a persistent underestimate in isotopically determined glucose appearance rate.	Glucose	20-27	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
2148133-4	1990	In vivo peripheral insulin sensitivity (euglycaemic clamp with insulin infusion of 40, 160, and 600 mU m-2 min-1, respectively) was significantly improved (glucose requirement: to 4.7 +/- 1.0 from 3.0 +/- 0.6 mg kg-1 min-1, p less than 0.05 at first insulin level; to 10.8 +/- 0.5 from 9.3 +/- 0.7 mg kg-1 min-1, p less than 0.01 at second level; to 13.3 +/- 0.6 from 11.8 +/- 0.8 mg kg-1 min-1, p less than 0.025 at third level).	Glucose	156-163	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
2148133-5	1990	Basal hepatic glucose production was also significantly reduced (from 4.3 +/- 0.4 to 3.3 +/- 0.3 mg kg-1 min-1, p less than 0.05), and residual glucose production further suppressed after insulin supplement (from 1.1 +/- 0.4 to 0.3 +/- 0.2 mg kg-1 min-1 after 120 min at 100 mU l-1 plasma insulin, p less than 0.05).	Glucose	14-21	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
2282921-2	1990	At the lowest dose used (4.3 mg min-1) adenosine increased minute ventilation by 44% (P less than 0.01, n = 11) and reduced pulmonary vascular resistance by 20% (P less than 0.05) without causing other significant haemodynamic changes.	Adenosine	39-48	CD59 molecule (CD59 blood group)	Homo sapiens	32-37
2282930-5	1990	Peak pacing GCVF decreased slightly but non-significantly after drug administration from 84 +/- 20 to 79 +/- 24 ml min-1, while ARCR increased, but again non-significantly, from 1.36 +/- 0.44 to 1.45 +/- 0.45.	gcvf	12-16	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
2282930-6	1990	Analysis of individual patient responses revealed that propranolol prolonged peak pacing time and hence peak pacing heart rate (from 126 +/- 24 to 140 +/- 23 beats min-1, P less than 0.05) in five patients.	Propranolol	55-66	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
2272963-3	1990	The maximal rate of glucose disposal attained during the clamp averaged 15.7 +/- 1.0 mg.kg lean body mass-1.min-1 after exercise vs. a control value of 15.4 mg.kg lean body mass-1.min-1.	Glucose	20-27	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
2275356-3	1990	On the metyrapone trial day, the mean value of Ko was 0.63 +/- 0.15 min-1 x 10(-2).	Metyrapone	7-17	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
2270875-7	1990	The flow-rate of the nitrogen carrier gas was 30 ml min-1.	Nitrogen	21-29	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
2291871-4	1990	Pharmacokinetic analysis showed that this observation resulted from a reduced oral clearance of proguanil in these individuals (245, 534 and 552 ml min-1) compared with the rest of the population (858 +/- 482 ml min-1).	Proguanil	96-105	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
2176911-2	1990	Under standard assay conditions, addition of 5 mM EDTA efficiently prevented the degradation of both human and rat GRF for at least 3 h. Association of the ligand was time-dependent: equilibrium was reached within 30 min of incubation at 23 degrees C and remained stable for an additional 150 min (K1 = 5.01 +/- 0.86 nM-1.min-1).	Edetic Acid	50-54	CD59 molecule (CD59 blood group)	Homo sapiens	322-327
2076569-2	1990	14 alpha-Hydroxyandrost-4-ene-3,6,17-trione was the most potent inhibitor showing a time-dependent, pseudo-first-order inactivation of aromatase in the presence of reduced nicotinamide adenine dinucleotide phosphate with apparent Ki of 1.3 microM and Kinact of 0.23 min-1.	alpha-hydroxyandrost-4-ene-3,6,17-trione	3-43	CD59 molecule (CD59 blood group)	Homo sapiens	266-271
2076569-2	1990	14 alpha-Hydroxyandrost-4-ene-3,6,17-trione was the most potent inhibitor showing a time-dependent, pseudo-first-order inactivation of aromatase in the presence of reduced nicotinamide adenine dinucleotide phosphate with apparent Ki of 1.3 microM and Kinact of 0.23 min-1.	NADP	172-215	CD59 molecule (CD59 blood group)	Homo sapiens	266-271
2265641-5	1990	Cardiac NA overflow based on 3H-NA extraction over the heart increased from 182 to 1046 pmol min-1 in the VVI mode (P less than 0.01) and from 178 to 793 pmol min-1 in the TX mode (P less than 0.001).	Tritium	29-31	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
2254590-4	1990	With thiosulfate as a substrate, the Km for rhodanese was 6.7 mM and the Vmax was 0.67 mumol thiocyanate min-1 mg-1 protein.	Thiosulfates	5-16	CD59 molecule (CD59 blood group)	Homo sapiens	105-115
2254590-4	1990	With thiosulfate as a substrate, the Km for rhodanese was 6.7 mM and the Vmax was 0.67 mumol thiocyanate min-1 mg-1 protein.	thiocyanate	93-104	CD59 molecule (CD59 blood group)	Homo sapiens	105-115
1977772-6	1990	Conversely, after tertatolol at t3, renal blood flow was increased (from 426 +/- 18 mL/min/1.73 m2 to 509 +/- 56 mL/min/1.73 m2, P = .03), renal vascular resistance and renal arteriovenous oxygen difference were decreased (P less than .001), and the renal blood flow/cardiac output ratio was increased (P = .03).	tertatolol	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
1977772-6	1990	Conversely, after tertatolol at t3, renal blood flow was increased (from 426 +/- 18 mL/min/1.73 m2 to 509 +/- 56 mL/min/1.73 m2, P = .03), renal vascular resistance and renal arteriovenous oxygen difference were decreased (P less than .001), and the renal blood flow/cardiac output ratio was increased (P = .03).	tertatolol	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
1698362-1	1990	HRF20, a 20 kDa homologous restriction factor, is a membrane glycoprotein anchored via galactosyl phosphatidyl inositol.	Phosphatidylinositols	98-119	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
1698362-1	1990	HRF20, a 20 kDa homologous restriction factor, is a membrane glycoprotein anchored via galactosyl phosphatidyl inositol.	Phosphatidylinositols	98-119	CD59 molecule (CD59 blood group)	Homo sapiens	9-45
2394726-2	1990	Each enzyme had substantial activity with apparent Km and Vmax for dehydroascorbate between 0.2 and 2.2 mM and 6-27 nmol min-1, respectively, and for gluathione between 1.6 and 8.7 mM and 11-30 nmol min-1, respectively.	Dehydroascorbic Acid	67-83	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
2394726-2	1990	Each enzyme had substantial activity with apparent Km and Vmax for dehydroascorbate between 0.2 and 2.2 mM and 6-27 nmol min-1, respectively, and for gluathione between 1.6 and 8.7 mM and 11-30 nmol min-1, respectively.	Dehydroascorbic Acid	67-83	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
2394726-2	1990	Each enzyme had substantial activity with apparent Km and Vmax for dehydroascorbate between 0.2 and 2.2 mM and 6-27 nmol min-1, respectively, and for gluathione between 1.6 and 8.7 mM and 11-30 nmol min-1, respectively.	gluathione	150-160	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
2394726-2	1990	Each enzyme had substantial activity with apparent Km and Vmax for dehydroascorbate between 0.2 and 2.2 mM and 6-27 nmol min-1, respectively, and for gluathione between 1.6 and 8.7 mM and 11-30 nmol min-1, respectively.	gluathione	150-160	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
2394726-5	1990	The apparent Km for DHA was 1.0 mM and the Vmax was 8 nmol min-1, and for GSH were 3.9 mM and 14 nmol min-1, respectively.	Dehydroascorbic Acid	20-23	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
2394726-5	1990	The apparent Km for DHA was 1.0 mM and the Vmax was 8 nmol min-1, and for GSH were 3.9 mM and 14 nmol min-1, respectively.	Dehydroascorbic Acid	20-23	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
2394726-5	1990	The apparent Km for DHA was 1.0 mM and the Vmax was 8 nmol min-1, and for GSH were 3.9 mM and 14 nmol min-1, respectively.	Glutathione	74-77	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
2091489-4	1990	Trace amounts of iron are quantitatively retained on naphthalene in the pH range 3.5-7.5 and at a flow-rate of 1-2 ml min-1.	Iron	17-21	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
1977432-6	1990	Dopexamine 4 micrograms kg-1 min-1 produced an increase in cardiac index of 117% caused by a 65% reduction in afterload and an increase in heart rate by 61%.	dopexamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
1977432-7	1990	Dopamine 5 micrograms kg-1 min-1 caused a 40% increase in cardiac index as a result of an increase in stroke volume.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
2208532-2	1990	In comparison with baseline measurements, nitrous oxide administration resulted in small but statistically significant (P less than 0.05) changes in mean arterial pressure (76 +/- 14 to 67 +/- 12), mean pulmonary arterial pressure (37 +/- 14 to 33 +/- 13 mmHg), and cardiac output (3.7 +/- 1.4 to 3.2 +/- 1.1 L.min-1).	Nitrous Oxide	42-55	CD59 molecule (CD59 blood group)	Homo sapiens	311-316
2226427-7	1990	In the heaviest tasks the oxygen consumption was 1.2 +/- 0.41 min-1, and no elevated blood lactate concentrations were found.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
2166475-2	1990	Kinetic analysis of the data showed a good fit to a pseudo first order curve, with an apparent velocity constant k = 1.26 x 10(-2) min-1 and a maximum modification of 9.6 out of the 11 arginines of the molecule.	Arginine	185-194	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
2167380-1	1990	In human metallothionein-2, the exchange rate constants of ten amide protons were found to range from 1.7 x 10(-4) to 1 x 10(-1) min-1 at pH 6.3 and 8 degrees C. Most of these slowly exchanging protons could be associated with hydrogen bonds in secondary structure elements of the alpha-domain.	Amides	63-68	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
2167380-1	1990	In human metallothionein-2, the exchange rate constants of ten amide protons were found to range from 1.7 x 10(-4) to 1 x 10(-1) min-1 at pH 6.3 and 8 degrees C. Most of these slowly exchanging protons could be associated with hydrogen bonds in secondary structure elements of the alpha-domain.	Hydrogen	227-235	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
2166435-9	1990	Leg leucine plus KIC release was reduced by insulin (120 +/- 17 vs. 84 +/- 10 nmol.100 g-1.min-1; P = 0.005); endogenous leucine appearance of leucine and phenylalanine decreased with insulin (leucine, 1.97 +/- 0.08 vs. 1.65 +/- 0.10; phenylalanine, 0.76 +/- 0.03 vs. 0.54 +/- 0.08 mumols.kg-1.min-1; P less than 0.02).	Leucine	121-128	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
2166435-9	1990	Leg leucine plus KIC release was reduced by insulin (120 +/- 17 vs. 84 +/- 10 nmol.100 g-1.min-1; P = 0.005); endogenous leucine appearance of leucine and phenylalanine decreased with insulin (leucine, 1.97 +/- 0.08 vs. 1.65 +/- 0.10; phenylalanine, 0.76 +/- 0.03 vs. 0.54 +/- 0.08 mumols.kg-1.min-1; P less than 0.02).	Leucine	121-128	CD59 molecule (CD59 blood group)	Homo sapiens	294-299
2166435-9	1990	Leg leucine plus KIC release was reduced by insulin (120 +/- 17 vs. 84 +/- 10 nmol.100 g-1.min-1; P = 0.005); endogenous leucine appearance of leucine and phenylalanine decreased with insulin (leucine, 1.97 +/- 0.08 vs. 1.65 +/- 0.10; phenylalanine, 0.76 +/- 0.03 vs. 0.54 +/- 0.08 mumols.kg-1.min-1; P less than 0.02).	Leucine	121-128	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
2166435-9	1990	Leg leucine plus KIC release was reduced by insulin (120 +/- 17 vs. 84 +/- 10 nmol.100 g-1.min-1; P = 0.005); endogenous leucine appearance of leucine and phenylalanine decreased with insulin (leucine, 1.97 +/- 0.08 vs. 1.65 +/- 0.10; phenylalanine, 0.76 +/- 0.03 vs. 0.54 +/- 0.08 mumols.kg-1.min-1; P less than 0.02).	Leucine	121-128	CD59 molecule (CD59 blood group)	Homo sapiens	294-299
2119677-14	1990	oral clearance of tenoxicam was 2.5 (1.5) ml min-1 and appeared slightly higher than in previous studies.	tenoxicam	18-27	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
2165828-8	1990	While neutralization of in situ generated factor IXa in normal plasma was negligible, unfractionated heparin dramatically enhanced the rate of inactivation of factor IXa (apparent second order rate constant of inhibition of 5.2 min-1/per microgram heparin/mL).	Heparin	101-108	CD59 molecule (CD59 blood group)	Homo sapiens	228-233
2165828-9	1990	The synthetic pentasaccharide heparin, the smallest heparin chain capable of binding antithrombin III, stimulated the inhibition of in situ generated factor IXa, but sevenfold less than unfractionated heparin (k = 0.76 min-1 per microgram pentasaccharide/mL).	pentasaccharide heparin	14-37	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
2165828-9	1990	The synthetic pentasaccharide heparin, the smallest heparin chain capable of binding antithrombin III, stimulated the inhibition of in situ generated factor IXa, but sevenfold less than unfractionated heparin (k = 0.76 min-1 per microgram pentasaccharide/mL).	Heparin	30-37	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
2165828-9	1990	The synthetic pentasaccharide heparin, the smallest heparin chain capable of binding antithrombin III, stimulated the inhibition of in situ generated factor IXa, but sevenfold less than unfractionated heparin (k = 0.76 min-1 per microgram pentasaccharide/mL).	pentasaccharide	14-29	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
1973638-8	1990	At a matched paced heart rate of 98 +/- 15 min-1, the time constant of left ventricular isovolumic relaxation was significantly reduced by bucindolol therapy (92 +/- 17 versus 73 +/- 11 msec, p = 0.0013), and the relation of the time constant to end-systolic pressure was shifted downward (p = 0.014) with therapy.	bucindolol	139-149	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
2167802-8	1990	Adenosine (infused in steps from 40 to 80 micrograms min-1 kg-1 into a central vein) elicited a gradual reduction in the peripheral vascular resistance to less than 50% of the basal level.	Adenosine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	53-63
2167802-12	1990	Skin blood flow increased by 100% at 50 micrograms of adenosine min-1 kg-1, whereas splanchnic blood flow rose significantly at 60 micrograms of adenosine min-1 kg-1.	Adenosine	145-154	CD59 molecule (CD59 blood group)	Homo sapiens	155-165
2167806-8	1990	Forearm non-esterified fatty acid uptake increased with the Lipid infusion (+50 +/- 10 nmol min-1 100 ml-1 of forearm) and was accompanied by a significant decrease in forearm glucose uptake (+3.23 +/- 0.25 versus +3.65 +/- 0.35 mumol min-1 100 ml-1 of forearm, Lipid and Control, respectively; P less than 0.05) and alanine release (-84 +/- 12 versus -113 +/- 15 nmol min-1 100 ml-1 of forearm, Lipid and Control, respectively; P less than 0.05).	Fatty Acids	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
2167806-8	1990	Forearm non-esterified fatty acid uptake increased with the Lipid infusion (+50 +/- 10 nmol min-1 100 ml-1 of forearm) and was accompanied by a significant decrease in forearm glucose uptake (+3.23 +/- 0.25 versus +3.65 +/- 0.35 mumol min-1 100 ml-1 of forearm, Lipid and Control, respectively; P less than 0.05) and alanine release (-84 +/- 12 versus -113 +/- 15 nmol min-1 100 ml-1 of forearm, Lipid and Control, respectively; P less than 0.05).	Fatty Acids	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	235-240
2167806-8	1990	Forearm non-esterified fatty acid uptake increased with the Lipid infusion (+50 +/- 10 nmol min-1 100 ml-1 of forearm) and was accompanied by a significant decrease in forearm glucose uptake (+3.23 +/- 0.25 versus +3.65 +/- 0.35 mumol min-1 100 ml-1 of forearm, Lipid and Control, respectively; P less than 0.05) and alanine release (-84 +/- 12 versus -113 +/- 15 nmol min-1 100 ml-1 of forearm, Lipid and Control, respectively; P less than 0.05).	Fatty Acids	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	235-240
2379384-7	1990	Mean clearance in two patients with creatinine clearance values greater than 150 ml/min/1.73 m2 was 17.7 L/hr/1.73 m2.	Creatinine	36-46	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
2379384-8	1990	Mean clearance in two patients with creatinine clearance values less than 50 ml/min/1.73 m2 was 8.5 L/hr/1.73 m2.	Creatinine	36-46	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
2379384-10	1990	Creatinine clearance ranged from 17 to 218 ml/min/1.73 m2.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
2272714-4	1990	They received metformin as the sole therapy when possible (sulfonylureas were discontinued in 9 cases) at a dosage of either 850 mg or 1,700 mg/day dependent on creatinine clearance values of 30-60 ml.min-1 (n = 11) and greater than 60 ml.min-1 (n = 13), respectively.	Metformin	14-23	CD59 molecule (CD59 blood group)	Homo sapiens	201-206
2390434-14	1990	clearance (CL/F) was 0.78 +/- 0.27 ml min-1 kg-1, and the apparent terminal elimination half-life (t1/2) was 11.6 +/- 7.9 days.	Fluorine	14-15	CD59 molecule (CD59 blood group)	Homo sapiens	38-48
2200838-5	1990	Both glucose uptake (5.0 +/- 0.6 vs 6.2 +/- 0.7 mg kg-1 min-1; P less than 0.05) and tissue sensitivity (M/I; 0.08 +/- 0.02 vs. 0.1 +/- 0.02 mg kg-1 min-1/mU l-1; P less than 0.05) increased between the first and second euglycaemic clamp (40 mU m-2 min-1).	Glucose	5-12	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
2231849-6	1990	Mean values for peak oxygen uptake were 48 +/- 7 ml kg-1 min-1 and 42 +/- 7 ml kg-1 min-1 in boys and girls respectively.	Oxygen	21-27	CD59 molecule (CD59 blood group)	Homo sapiens	57-89
2371578-2	1990	Oxygen, at 8 litres min-1, was delivered through a facemask via a circle absorber with a 2 litre reservoir bag.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	20-25
1983143-10	1990	After oral administration, renal clearance of theophylline was higher at steady state than after a single dose (0.58 +/- 0.06 L h-1 kg-1 vs 0.23 +/- 0.03 L h-1 kg-1), while urine flow rate was lower (1.1 +/- 0.5 mL min-1 vs 1.8 +/- 0.9 mL min-1).	Theophylline	46-58	CD59 molecule (CD59 blood group)	Homo sapiens	215-220
1983143-10	1990	After oral administration, renal clearance of theophylline was higher at steady state than after a single dose (0.58 +/- 0.06 L h-1 kg-1 vs 0.23 +/- 0.03 L h-1 kg-1), while urine flow rate was lower (1.1 +/- 0.5 mL min-1 vs 1.8 +/- 0.9 mL min-1).	Theophylline	46-58	CD59 molecule (CD59 blood group)	Homo sapiens	239-244
2165892-6	1990	Oxygen uptake was reduced from 147 +/- 16 ml STP min-1 m-2 in the control subjects to 112 +/- 9 ml STP min-1 m-2 in the patients.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
2165892-6	1990	Oxygen uptake was reduced from 147 +/- 16 ml STP min-1 m-2 in the control subjects to 112 +/- 9 ml STP min-1 m-2 in the patients.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
2142040-3	1990	During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05).	Cyclosporine	38-49	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
2142039-6	1990	Glucose requirement during the clamp was decreased in the Type 2 diabetic patients at presentation (2.2 +/- 0.7 vs 7.3 +/- 0.6 mg kg-1 min-1, p less than 0.001), and despite improvement following dietary treatment to 3.3 +/- 0.6 mg kg-1 min-1 (p less than 0.01) remained lower than in the control subjects (p less than 0.001).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
2142039-6	1990	Glucose requirement during the clamp was decreased in the Type 2 diabetic patients at presentation (2.2 +/- 0.7 vs 7.3 +/- 0.6 mg kg-1 min-1, p less than 0.001), and despite improvement following dietary treatment to 3.3 +/- 0.6 mg kg-1 min-1 (p less than 0.01) remained lower than in the control subjects (p less than 0.001).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	237-242
2142040-3	1990	During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05).	Cyclosporine	38-51	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
2142040-3	1990	During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05).	Cyclosporine	38-51	CD59 molecule (CD59 blood group)	Homo sapiens	270-275
2142040-3	1990	During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05).	Cyclosporine	38-51	CD59 molecule (CD59 blood group)	Homo sapiens	270-275
2142040-3	1990	During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05).	Cyclosporine	38-49	CD59 molecule (CD59 blood group)	Homo sapiens	270-275
2142040-3	1990	During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05).	Cyclosporine	38-49	CD59 molecule (CD59 blood group)	Homo sapiens	270-275
2114990-1	1990	A continuous intravenous infusion of L-leucine (300 mumols min-1) was given to 12 healthy females over a 2 1/2 h period.	Leucine	37-46	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
2365292-3	1990	Apparent clearance of oxazepam in cirrhotic patients was 0.55 ml.min-1.kg-1, with a range of 0.46 to 1.24 ml.min-1.kg-1, compared with 1.19 ml.min-1.kg-1 and a range of 0.80 to 1.66 ml.min-1.kg-1 in the controls (p less than 0.05).	Oxazepam	22-30	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
2365292-3	1990	Apparent clearance of oxazepam in cirrhotic patients was 0.55 ml.min-1.kg-1, with a range of 0.46 to 1.24 ml.min-1.kg-1, compared with 1.19 ml.min-1.kg-1 and a range of 0.80 to 1.66 ml.min-1.kg-1 in the controls (p less than 0.05).	Oxazepam	22-30	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
2365292-3	1990	Apparent clearance of oxazepam in cirrhotic patients was 0.55 ml.min-1.kg-1, with a range of 0.46 to 1.24 ml.min-1.kg-1, compared with 1.19 ml.min-1.kg-1 and a range of 0.80 to 1.66 ml.min-1.kg-1 in the controls (p less than 0.05).	Oxazepam	22-30	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
2365292-3	1990	Apparent clearance of oxazepam in cirrhotic patients was 0.55 ml.min-1.kg-1, with a range of 0.46 to 1.24 ml.min-1.kg-1, compared with 1.19 ml.min-1.kg-1 and a range of 0.80 to 1.66 ml.min-1.kg-1 in the controls (p less than 0.05).	Oxazepam	22-30	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
2365292-4	1990	The unbound clearance of oxazepam in patients was 4.1 ml.min-1.kg-1, with a range of 3.4 to 5.5 ml.min-1.kg-1, compared with 25.4 ml.min-1.kg-1, and a range of 16.7 to 43.7 ml.min-1.kg-1, p less than 0.001, in the controls.	Oxazepam	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
2365292-4	1990	The unbound clearance of oxazepam in patients was 4.1 ml.min-1.kg-1, with a range of 3.4 to 5.5 ml.min-1.kg-1, compared with 25.4 ml.min-1.kg-1, and a range of 16.7 to 43.7 ml.min-1.kg-1, p less than 0.001, in the controls.	Oxazepam	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
2365292-4	1990	The unbound clearance of oxazepam in patients was 4.1 ml.min-1.kg-1, with a range of 3.4 to 5.5 ml.min-1.kg-1, compared with 25.4 ml.min-1.kg-1, and a range of 16.7 to 43.7 ml.min-1.kg-1, p less than 0.001, in the controls.	Oxazepam	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
2365292-4	1990	The unbound clearance of oxazepam in patients was 4.1 ml.min-1.kg-1, with a range of 3.4 to 5.5 ml.min-1.kg-1, compared with 25.4 ml.min-1.kg-1, and a range of 16.7 to 43.7 ml.min-1.kg-1, p less than 0.001, in the controls.	Oxazepam	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
2373580-3	1990	The mean values at LT, FBLC of 2.0, 2.5, 4.0 mM and max for VO2 were 52.7, 56.4, 58.0, 61.2 and 63.5 ml/kg.min -1, respectively: for velocity they were 237.4, 252.2, 260.6, 274.4 and 286.5 m/min, respectively; and for HR were 165.7, 172.7, 176.5, 182.3 and 187.4 bts/min, respectively.	Pyruvic Acid	263-266	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
2341387-2	1990	Neutral endopeptidase 24.11 is rapidly inactivated by N-bromoacetyl-D-leucylglycine in a reaction which follows first-order kinetics at pH 8 and 37 degrees C. The concentration dependence of inactivation revealed saturation kinetics with an apparent Ki of 10 mM and kappa inact of 0.4 min-1 at saturating inhibitor concentration.	n-bromoacetyl-d-leucylglycine	54-83	CD59 molecule (CD59 blood group)	Homo sapiens	285-290
2350538-3	1990	All lactones undergo rapid acylation (ka varies from 17 to 170 min-1) that shows little enantioselectivity; there is, however, pronounced enantioselectivity in substrate binding for three of the lactones [Ks(R/S) = 40-110].	Lactones	4-12	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
2111189-4	1990	The peak plasma levels of the enantiomers, observed at less than or equal to 2 h after dosing, were similar but plasma clearances and terminal half-lives were different after oral administration of (R)-tocainide (195.5 +/- 20.1 ml min-1 and 9.7 +/- 0.8 h) and (S)-tocainide (110.2 +/- 10.5 ml min-1 and 14.5 +/- 1.7 h).	Tocainide	198-211	CD59 molecule (CD59 blood group)	Homo sapiens	231-236
1972334-2	1990	Twenty patients scheduled for aorto-coronary bypass grafting suffering from tachycardia (heart rate (HR) greater than 100 beat min-1) were treated by infusion of esmolol, an ultra-short acting, selective beta 1-blocker.	esmolol	162-169	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
2112405-10	1990	Flosequinan increased the oxygen uptake at anaerobic threshold from 13.2 +/- 2.8 ml min-1 kg-1 to 15.9 +/- 3.4 ml min-1 kg-1 at week 2 and 15.8 +/- 3.7 ml min-1 kg-1 at week 8.	flosequinan	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	84-94
2112405-10	1990	Flosequinan increased the oxygen uptake at anaerobic threshold from 13.2 +/- 2.8 ml min-1 kg-1 to 15.9 +/- 3.4 ml min-1 kg-1 at week 2 and 15.8 +/- 3.7 ml min-1 kg-1 at week 8.	flosequinan	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	114-124
2112405-10	1990	Flosequinan increased the oxygen uptake at anaerobic threshold from 13.2 +/- 2.8 ml min-1 kg-1 to 15.9 +/- 3.4 ml min-1 kg-1 at week 2 and 15.8 +/- 3.7 ml min-1 kg-1 at week 8.	flosequinan	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	114-124
2112405-10	1990	Flosequinan increased the oxygen uptake at anaerobic threshold from 13.2 +/- 2.8 ml min-1 kg-1 to 15.9 +/- 3.4 ml min-1 kg-1 at week 2 and 15.8 +/- 3.7 ml min-1 kg-1 at week 8.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	84-94
2140082-4	1990	The SMS infusion induced a reduction in the glomerular filtration rate (clearance of 125I-iothalamate) and renal plasma flow (131I-hippuran) from 140 +/- 15 (mean +/- SD) and 550 +/- 69 to 131 +/- 14 (2p less than 0.005) and 492 +/- 73 ml min-1 1.73-m-2 (2p less than 0.001), while filtration fraction and total renal resistance rose (both 2p less than 0.001).	Samarium	4-7	CD59 molecule (CD59 blood group)	Homo sapiens	239-244
2210020-4	1990	Their basal glucose productions, measured by [6,6(-2)H] glucose constant infusion, were 3.3, 2.6 and 3.4 mg kg-1 min-1, respectively; they did not correlate with fasting plasma glucose.	Glucose	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
2210020-5	1990	Glucose production in response to a 2 mg kg-1 min- unlabeled glucose infusion, was normally suppressed in L2, but was incompletely suppressed (by 1.5 mg kg-1 min-1) in L1 and L3.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
2350942-5	1990	With a reduction in arterial oxygen content of more than 20-25% the flow increase was sufficient to supply the heart with enough O2 during submaximal (heart rate 157 beats min-1) but not maximal exercise, in which case anaerobic glycolysis contributed significantly to the myocardial energy metabolism.	Oxygen	129-131	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
2375881-2	1990	2 The plasma clearance of metronidazole was 1.20 +/- 0.53 and 1.25 +/- 0.22 ml min-1 kg-1, the volume of distribution 0.77 +/- 0.27 and 0.77 +/- 0.09 1 kg-1 and the half-life 7.8 +/- 1.9 and 7.2 +/- 0.9 h in elderly and young subjects, respectively (P less than 0.05).	Metronidazole	26-39	CD59 molecule (CD59 blood group)	Homo sapiens	79-89
1691760-11	1990	When incorporated into the membrane, CD59 inhibited binding of 125I-C9 to membrane C5b-8 and reduced the extent of formation of SDS-resistant C9 polymer.	Sodium Dodecyl Sulfate	128-131	CD59 molecule (CD59 blood group)	Homo sapiens	37-41
2341826-3	1990	The oral plasma clearance of nifedipine was 1189 +/- 876 ml min-1, and the mean plasma half-life (t1/2) was 5.99 +/- 3.05 h. The pyridine metabolite was not retained.	Nifedipine	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
2341826-3	1990	The oral plasma clearance of nifedipine was 1189 +/- 876 ml min-1, and the mean plasma half-life (t1/2) was 5.99 +/- 3.05 h. The pyridine metabolite was not retained.	pyridine	129-137	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
2110608-5	1990	After 16-hour fasting net glucose oxidation was 0.59 +/- 0.17 mg x kg-1 x min-1 and glucose tissue uptake 2.34 +/- 0.12 mg x kg-1 x min-1.	Glucose	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
2384947-10	1990	Naloxone 0.05-4 mg was administered intravenously in 21 patients (31.7%) whose respiratory rate was below 10 min-1.	Naloxone	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
2116678-6	1990	After training there were significant increases in mean maximal oxygen uptake (ml kg-1 min-1) from 23 (5) to 28 (6), oxygen pulse (ml/beat) from 8.8 (2.3) to 10.8 (2.4), and anaerobic threshold (1/min) from 1.11 (0.27) to 1.38 (0.33).	Oxygen	64-70	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
2354158-2	1990	The rate constant for association of retinol with the protein (ka) was found to be 1.5 X 10(6) M-1 min-1.	Vitamin A	37-44	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
2340265-1	1990	The reactivity of simple alkyl thiolates with N-ethylmaleimide (NEM) follows the Bronsted equation, log kS- = log G + beta pK, with G = 790 M-1 min-1 and beta = 0.43.	alkyl thiolates	25-40	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
2340265-1	1990	The reactivity of simple alkyl thiolates with N-ethylmaleimide (NEM) follows the Bronsted equation, log kS- = log G + beta pK, with G = 790 M-1 min-1 and beta = 0.43.	Ethylmaleimide	46-62	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
2340265-1	1990	The reactivity of simple alkyl thiolates with N-ethylmaleimide (NEM) follows the Bronsted equation, log kS- = log G + beta pK, with G = 790 M-1 min-1 and beta = 0.43.	Ethylmaleimide	64-67	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
2340265-1	1990	The reactivity of simple alkyl thiolates with N-ethylmaleimide (NEM) follows the Bronsted equation, log kS- = log G + beta pK, with G = 790 M-1 min-1 and beta = 0.43.	Potassium	104-106	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
2165407-2	1990	The initial rate of peroxidase"s oxidation is directly proportional to the periodate concentration; the oxidation rate constant of peroxidase carbohydrate moiety is 1.23 x 10(-3) M-1 min-1.	metaperiodate	75-84	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
2165407-2	1990	The initial rate of peroxidase"s oxidation is directly proportional to the periodate concentration; the oxidation rate constant of peroxidase carbohydrate moiety is 1.23 x 10(-3) M-1 min-1.	Carbohydrates	142-154	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
2328191-4	1990	The plasma clearance of diflunisal was lowered significantly after multiple dose administration (5.2 +/- 1.2 and 4.2 +/- 0.7 ml min-1 for the 250 and 500 mg twice daily regimens, respectively) as compared with single dose administration 11.4 +/- 3.1 and 9.9 +/- 2.0 ml min-1 for the 250 and 500 mg single doses, respectively).	Diflunisal	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
2328191-4	1990	The plasma clearance of diflunisal was lowered significantly after multiple dose administration (5.2 +/- 1.2 and 4.2 +/- 0.7 ml min-1 for the 250 and 500 mg twice daily regimens, respectively) as compared with single dose administration 11.4 +/- 3.1 and 9.9 +/- 2.0 ml min-1 for the 250 and 500 mg single doses, respectively).	Diflunisal	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	269-274
1692709-5	1990	The number and the distribution of cysteine residues were conserved, implying that the CD59 represented a human homologue of murine Ly-6.	Cysteine	35-43	CD59 molecule (CD59 blood group)	Homo sapiens	87-91
2185023-1	1990	Systemic and coronary haemodynamic effects of carbochromen (0.125 mg kg-1 min-1 for 40 min i.v.)	Chromonar	46-58	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
2185023-6	1990	In response to dipyridamole (n = 12) heart rate increased from 73 to 94 beats min-1 (P less than 0.005) and mean aortic pressure fell from 89 to 78 mmHg (P less than 0.001).	Dipyridamole	15-27	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
2355823-6	1990	Phosphate loading significantly increased maximal oxygen uptake from 4.77 +/- 0.29 to 5.18 +/- 0.25 l.min-1 and ventilatory anaerobic threshold from 3.74 +/- 0.28 to 4.18 +/- 0.14 l.min-1.	Phosphates	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
2355823-6	1990	Phosphate loading significantly increased maximal oxygen uptake from 4.77 +/- 0.29 to 5.18 +/- 0.25 l.min-1 and ventilatory anaerobic threshold from 3.74 +/- 0.28 to 4.18 +/- 0.14 l.min-1.	Phosphates	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
2355823-8	1990	However, mean performance run oxygen uptake was significantly lower (3.87 +/- 0.3 to 3.80 +/- 0.3 l.min-1) with phosphate ingestion.	Oxygen	30-36	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
2355823-8	1990	However, mean performance run oxygen uptake was significantly lower (3.87 +/- 0.3 to 3.80 +/- 0.3 l.min-1) with phosphate ingestion.	Phosphates	112-121	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
2305977-5	1990	Total clearance of ropivacaine was lower in the pregnant animals (21.6 +/- 4.5 mL.min-1.kg-1) compared with the nonpregnant animals (45.1 +/- 6.7 mL.min-1.kg-1).	Ropivacaine	19-30	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
2388711-2	1990	The molecular weight, isoelectric point, optimum pH, Km value for PGE2, and turnover number were 34,000, 8.2, 6.5-7.5, 1.0 mM, and 7.6 min-1, respectively.	Dinoprostone	66-70	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
2346532-1	1990	Catecholamine metabolism was assessed in 14 patients with chronic congestive heart failure (NYHA class IV; cardiac index 2.4 +/- 0.2 l min-1, ejection fraction 20 +/- 11%) on levodopa (L-Dopa-ratiopharm) treatment: 1. prior to the start of levodopa treatment; 2. following acute administration of levodopa in the 14 patients and in 4 healthy control subjects; 3. after 30 days +/- 1 day with 2-4 g levodopa p.o.	Catecholamines	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
2183874-9	1990	Total Pt had a larger Vdss (117 l m-2) and a lower total body clearance (14 ml min-1 m-2) than free Pt and carboplatin.	Platinum	6-8	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
2109626-4	1990	The mean value for oxygen consumption was 3.25 ml kg-1 min-1, declining by 8% during the 2 h of anaesthesia.	Oxygen	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
2109626-6	1990	t-0.48 ml kg-1 min-1 when FIN2O was 0.7.	fin2o	26-31	CD59 molecule (CD59 blood group)	Homo sapiens	15-20
2311228-6	1990	The mean rate constant for all materials was 0.23 min-1 for the aca and 1.42 min-1 for the RA-1000, significantly different (P less than 0.001).	Radium	91-93	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
1689219-4	1990	CD59 is a widely distributed 18,000-25,000 Mr protein anchored to the cell membrane by phosphatidylinositol (PI).	Phosphatidylinositols	87-107	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
1968893-6	1990	Whole body noradrenaline spillover, a potentially more accurate measure of overall sympathetic activity than concentration of noradrenaline in plasma, was 235 +/- 20 ng min-1 m-2 in controls, was similar in subjects with stable angina (no beta-blockers; 260 +/- 34 ng min-1 m-2, beta-blockers; 200 +/- 17 ng min-1 m-2), but was increased in patients with unstable angina (310 +/- 27 ng min-1 m-2, P less than 0.05), with recent acute myocardial infarction (346 +/- 40 ng min-1 m-2, P less than 0.05) or with heart failure (438 +/- 65 ng min-1 m-2, P less than 0.01).	Norepinephrine	11-24	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2139398-4	1990	Following captopril 12.5 mg orally the diabetic patients exhibited an acute fall in GFR from 122 +/- 3.8 to 113 +/- 4.5 ml min-1 1.73-m-2 (p less than 0.02) and a rise in renal plasma flow (RPF) from 670 +/- 57 to 797 +/- 46 ml min-1 1.73-m-2 (p less than 0.01) which resulted in a fall in filtration.	Captopril	10-19	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
2139398-4	1990	Following captopril 12.5 mg orally the diabetic patients exhibited an acute fall in GFR from 122 +/- 3.8 to 113 +/- 4.5 ml min-1 1.73-m-2 (p less than 0.02) and a rise in renal plasma flow (RPF) from 670 +/- 57 to 797 +/- 46 ml min-1 1.73-m-2 (p less than 0.01) which resulted in a fall in filtration.	Captopril	10-19	CD59 molecule (CD59 blood group)	Homo sapiens	228-233
2318228-2	1990	Dobutamine-ECG test (dose of 5, 10, 15 and 20 micrograms kg-1 min-1 every 5 min) was performed 5 to 12 days after the beginning of the symptoms of AMI, and coronary angiography within the first month.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
1690178-2	1990	HRF20 has been identified by a monoclonal antibody (mAb), 1F5, and is one of the phosphatidylinositol(PI)-anchored cell-surface glycoproteins.	Phosphatidylinositols	81-101	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
2107137-3	1990	Oxygen consumption (ml/min/1.73 m2) in normal subjects, in patients with acute hepatitis and in patients with cirrhosis was 206.5 +/- 4.0 (mean +/- S.E.M.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	23-28
1689670-0	1990	Analysis of PI (phosphatidylinositol)-anchoring antigens in a patient of paroxysmal nocturnal hemoglobinuria (PNH) reveals deficiency of 1F5 antigen (CD59), a new complement-regulatory factor.	Phosphatidylinositols	16-36	CD59 molecule (CD59 blood group)	Homo sapiens	137-148
2107391-4	1990	When L(SH)2 was used, peroxidase activity was independent of the concentration of L(SH)2 in the concentration range studied (5 microM to 2 mM) and peroxide removal was only dependent on the concentration of H2O2 and ebselen, with the second-order rate constant being 12.3 +/- 0.8 mM-1 min-1.	Peroxides	147-155	CD59 molecule (CD59 blood group)	Homo sapiens	285-290
1689670-0	1990	Analysis of PI (phosphatidylinositol)-anchoring antigens in a patient of paroxysmal nocturnal hemoglobinuria (PNH) reveals deficiency of 1F5 antigen (CD59), a new complement-regulatory factor.	Phosphatidylinositols	16-36	CD59 molecule (CD59 blood group)	Homo sapiens	150-154
2155543-5	1990	The VIP-induced decrease in phosphate uptake was due to decrease in maximal transport (VmaxVIP = 2.78 +/- 0.16 nmol.mg protein-1.3 min-1) and not to a change in the affinity of the transporter for phosphate (KmVIP = 0.11 +/- 0.01 mM phosphate).	Phosphates	28-37	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
2154462-3	1990	Binding of 125I-labeled scu-PA to HUVEC, performed at 4 degrees C, was saturable, reversible, and specific (k+1 4 +/- 1 X 10(6) min-1 M-1, k-1 6.2 +/- 1.4 X 10(-3) min-1, Kd 2.8 +/- 0.1 nM; Bmax 2.2 +/- 0.1 X 10(5) sites/cell; mean +/- S.E.).	Iodine-125	11-15	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
2154462-3	1990	Binding of 125I-labeled scu-PA to HUVEC, performed at 4 degrees C, was saturable, reversible, and specific (k+1 4 +/- 1 X 10(6) min-1 M-1, k-1 6.2 +/- 1.4 X 10(-3) min-1, Kd 2.8 +/- 0.1 nM; Bmax 2.2 +/- 0.1 X 10(5) sites/cell; mean +/- S.E.).	Iodine-125	11-15	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
2306414-4	1990	The pharmacokinetics of fluconazole were markedly affected by impaired renal function with the elimination of half-life in Group III (GFR less than 20 ml min-1) being approximately three times that observed in normal volunteers (Group I).	Fluconazole	24-35	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
2137755-5	1990	Insulin-mediated glucose disposal rose from 2.5 (1.5-8.0) (median (range] to 4.2 (2.3-8.4) mg kg-1 min-1 in the glipizide group (n = 9, p less than 0.01), but did not change in the placebo group.	Glipizide	112-121	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
2137755-5	1990	Insulin-mediated glucose disposal rose from 2.5 (1.5-8.0) (median (range] to 4.2 (2.3-8.4) mg kg-1 min-1 in the glipizide group (n = 9, p less than 0.01), but did not change in the placebo group.	Glucose	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
1969348-4	1990	The steady-state glucose infusion rate necessary to maintain a stable plasma glucose concentration of 4.4-5.0 mmol l-1 was significantly (P less than or equal to 0.001) higher in insulinoma patients (2.5 +/- 0.6 mg kg-1 min-1) than in pancreas resected patients (0.6 +/- 0.2 mg kg-1 min-1), or in control subjects (0.5 +/- 0.1 mg kg-1 min-1).	Glucose	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
1969348-4	1990	The steady-state glucose infusion rate necessary to maintain a stable plasma glucose concentration of 4.4-5.0 mmol l-1 was significantly (P less than or equal to 0.001) higher in insulinoma patients (2.5 +/- 0.6 mg kg-1 min-1) than in pancreas resected patients (0.6 +/- 0.2 mg kg-1 min-1), or in control subjects (0.5 +/- 0.1 mg kg-1 min-1).	Glucose	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	283-288
1969348-4	1990	The steady-state glucose infusion rate necessary to maintain a stable plasma glucose concentration of 4.4-5.0 mmol l-1 was significantly (P less than or equal to 0.001) higher in insulinoma patients (2.5 +/- 0.6 mg kg-1 min-1) than in pancreas resected patients (0.6 +/- 0.2 mg kg-1 min-1), or in control subjects (0.5 +/- 0.1 mg kg-1 min-1).	Glucose	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	283-288
2405136-5	1990	Mean creatinine clearance was 49.5 +/- 20 ml/min/1.73 m2.	Creatinine	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
2137889-9	1990	With 3 alpha-OHDg as substrate, 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSDH) activity was 1.0 +/- 0.3 nmol min-1 mg-1 protein which was five times greater than the activity of the 3 beta-HSDH towards 3 beta-OHDg.	alpha-ohdg	7-17	CD59 molecule (CD59 blood group)	Homo sapiens	114-124
2137889-9	1990	With 3 alpha-OHDg as substrate, 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSDH) activity was 1.0 +/- 0.3 nmol min-1 mg-1 protein which was five times greater than the activity of the 3 beta-HSDH towards 3 beta-OHDg.	beta-ohdg	209-218	CD59 molecule (CD59 blood group)	Homo sapiens	114-124
1963521-1	1990	The activity of inosine triphosphate pyrophosphohydrolase (ITPH) in human erythrocytes was found to be 1.50 +/- 0.39 mumol of inosine triphosphate (ITP) hydrolysed x min-1 per g Hb, and no measurable amount of ITP was detected.	Inosine Triphosphate	16-36	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
2311613-5	1990	Ach (70-700 nmol min-1) was infused selectively into a graft on the left anterior descending coronary artery, and the effect on vessel diameters was assessed by quantitative arteriography.	Acetylcholine	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	17-22
2311613-6	1990	In both groups 84% and 83%, respectively, of the arterial segments distal to the bypass anastomosis were contracted by ach (greater than or equal to 70 nmol min-1).	Acetylcholine	119-122	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
2109476-5	1990	It is recommended that flumazenil be administered carefully by titration in increments of 0.1 mg.min-1 to avoid emergence reactions by awakening too fast (tachycardia, hypertension).	Flumazenil	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
2109477-13	1990	In one patient who received no naloxone, the reversal of midazolam action induced a 16-fold increase in catecholamine levels (from 50 to 800 ng.l-1) associated with a tachycardia of 170 b.min-1 and hypertension of 160 mmHg.	Midazolam	57-66	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
1963521-1	1990	The activity of inosine triphosphate pyrophosphohydrolase (ITPH) in human erythrocytes was found to be 1.50 +/- 0.39 mumol of inosine triphosphate (ITP) hydrolysed x min-1 per g Hb, and no measurable amount of ITP was detected.	Inosine Triphosphate	59-62	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
1963521-1	1990	The activity of inosine triphosphate pyrophosphohydrolase (ITPH) in human erythrocytes was found to be 1.50 +/- 0.39 mumol of inosine triphosphate (ITP) hydrolysed x min-1 per g Hb, and no measurable amount of ITP was detected.	Inosine Triphosphate	148-151	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
2340003-2	1990	The results exhibit a marked reduction of the pyrazinamide total clearance (0.48 vs 0.84 ml.min-1.kg-1) and an increase in half-life from 9.19 h to 15.07 h in the patients group.	Pyrazinamide	46-58	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
1982835-2	1990	PD clearances for leucine, isoleucine, and valine were 3 ml/min/1.73 m2, compared to urinary clearances of 0.16 ml/min/1.73 m2 (0.4 ml/min/1.73 m2 for isoleucine).	Leucine	18-25	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
1982835-2	1990	PD clearances for leucine, isoleucine, and valine were 3 ml/min/1.73 m2, compared to urinary clearances of 0.16 ml/min/1.73 m2 (0.4 ml/min/1.73 m2 for isoleucine).	Valine	43-49	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
1688497-7	1990	These studies show that the effects of PIPLC on MIRL are similar to those observed for other human erythrocyte membrane proteins that are anchored by a glycosyl phosphatidylinositol moiety.	Glycosylphosphatidylinositols	152-181	CD59 molecule (CD59 blood group)	Homo sapiens	48-52
1967533-6	1990	These changes were greater in the standing position and were dose-dependent; for standing blood pressure and heart rate 1 h after administration there was a 7 mm Hg fall and 6 beats min-1 increase after 15 mg temazepam and a 10 mm Hg fall and 8 beats min-1 increase after 30 mg temazepam.	Temazepam	209-218	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
1967533-6	1990	These changes were greater in the standing position and were dose-dependent; for standing blood pressure and heart rate 1 h after administration there was a 7 mm Hg fall and 6 beats min-1 increase after 15 mg temazepam and a 10 mm Hg fall and 8 beats min-1 increase after 30 mg temazepam.	Temazepam	278-287	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
1980079-5	1990	The maximally isoprenaline-stimulated adenylate cyclase activity rose from 66 +/- 7 to 100 +/- 10 pmol cAMP min-1 mg-1 protein after 15 min of global ischaemia indicating the receptor-mediated sensitization of the beta-adrenergic system.	Isoproterenol	14-26	CD59 molecule (CD59 blood group)	Homo sapiens	108-118
1980079-5	1990	The maximally isoprenaline-stimulated adenylate cyclase activity rose from 66 +/- 7 to 100 +/- 10 pmol cAMP min-1 mg-1 protein after 15 min of global ischaemia indicating the receptor-mediated sensitization of the beta-adrenergic system.	Cyclic AMP	103-107	CD59 molecule (CD59 blood group)	Homo sapiens	108-118
1980079-8	1990	Additionally direct stimulation of the adenylate cyclase by forskolin revealed an increased enzyme activity after 15 min of global ischaemia (300 +/- 20 vs 378 +/- 25 pmol cAMP min-1 mg-1).	Colforsin	60-69	CD59 molecule (CD59 blood group)	Homo sapiens	177-187
1980079-8	1990	Additionally direct stimulation of the adenylate cyclase by forskolin revealed an increased enzyme activity after 15 min of global ischaemia (300 +/- 20 vs 378 +/- 25 pmol cAMP min-1 mg-1).	Cyclic AMP	172-176	CD59 molecule (CD59 blood group)	Homo sapiens	177-187
1980079-9	1990	Prolonged periods of ischaemia, however, caused a decline of the total adenylate cyclase activity (232 +/- 24 pmol cAMP min-1 mg-1 protein).	Cyclic AMP	115-119	CD59 molecule (CD59 blood group)	Homo sapiens	120-130
2297454-5	1990	The renal clearance of amiloride was lower in the elderly than in young subjects (102 +/- 36 ml min -1 vs 300 +/- 64 ml min-1, P less than 0.001) as was the urinary excretion of amiloride (36 +/- 13 vs 62 +/- 18% of the dose, P less than 0.01).	Amiloride	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	96-102
2363547-6	1990	Dopamine was used in 70% of cases at the dose of 3 micrograms.kg.min-1 to improve kidney and splanchnic perfusion.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
2400142-9	1990	Clearance of bupivacaine was 2.59 +/- 0.91 ml.min-1.kg-1.	Bupivacaine	13-24	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
2137065-4	1990	Glucose disposal rates were 2.5 +/- 0.3 (mean +/- SE) mg kg-1 min-1 during the follicular phase and 3.2 +/- 0.3 mg kg-1 min-1 in the luteal phase with low dose insulin, and 5.9 +/- 0.4 and 6.4 +/- 0.6 mg kg-1 min-1, respectively, with high dose insulin.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
2101061-4	1990	Mean maximum oxygen consumption (VO2max) was 61.21 +/- 5.36 ml kg-1 min-1.	Oxygen	13-19	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
2137065-4	1990	Glucose disposal rates were 2.5 +/- 0.3 (mean +/- SE) mg kg-1 min-1 during the follicular phase and 3.2 +/- 0.3 mg kg-1 min-1 in the luteal phase with low dose insulin, and 5.9 +/- 0.4 and 6.4 +/- 0.6 mg kg-1 min-1, respectively, with high dose insulin.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
2137065-4	1990	Glucose disposal rates were 2.5 +/- 0.3 (mean +/- SE) mg kg-1 min-1 during the follicular phase and 3.2 +/- 0.3 mg kg-1 min-1 in the luteal phase with low dose insulin, and 5.9 +/- 0.4 and 6.4 +/- 0.6 mg kg-1 min-1, respectively, with high dose insulin.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
2127569-3	1990	In the healthy subjects, the total body clearance of R(-)-tocainide was significantly greater than that of S(+)-tocainide (2.62 vs 1.70 ml.min-1.kg-1).	Tocainide	53-67	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
2335163-12	1990	The highest oxygen consumption seen was 2.08 l min-1 and maximum minute ventilation was 641.	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
2253674-3	1990	The plasma clearance was 6.85 ml.min-1 and the elimination half-life was 6.52 h. Midazolam was well tolerated during and after administration.	Midazolam	81-90	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
2257859-3	1990	Morning peak expiratory flow (PEF) was slightly but significantly higher with theophylline (363 l.min-1) than terbutaline (342 l.min-1).	Theophylline	78-90	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
2289489-7	1990	Pyridostigmine caused a slight slowing of fc (5 beats.min-1) which was consistent throughout the entire exposure (P less than 0.001) but was of no clinical significance.	Pyridostigmine Bromide	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
2338115-2	1990	The plasma clearance of diflunisal was significantly higher in men (0.169 ml.min-1.kg-1) and in women on OCS (0.165 ml.min-1.kg-1) as compared to control women (0.108 ml.min-1.kg-1).	Diflunisal	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
2338115-2	1990	The plasma clearance of diflunisal was significantly higher in men (0.169 ml.min-1.kg-1) and in women on OCS (0.165 ml.min-1.kg-1) as compared to control women (0.108 ml.min-1.kg-1).	Diflunisal	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
2338115-2	1990	The plasma clearance of diflunisal was significantly higher in men (0.169 ml.min-1.kg-1) and in women on OCS (0.165 ml.min-1.kg-1) as compared to control women (0.108 ml.min-1.kg-1).	Diflunisal	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
2338115-4	1990	Statistically significant increases, however, were only observed for the partial metabolic clearance of diflunisal by phenolic glucuronidation between men and women (2.91 vs. 1.85 ml.min-1 respectively), and for the partial clearance by acyl glucuronidation between OCS users and control women (4.81 vs. 3.01 ml.min-1 respectively).	Diflunisal	104-114	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
2340852-1	1990	Acetyl-L-carnitine 1.5 g and 3.0 g was administered as three divided doses on each of two occasions to 24 people with varying renal failure (creatinine clearance 127-8 ml.min-1).	Acetylcarnitine	0-18	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
2340852-4	1990	Patients whose creatinine clearance was below about 30-40 ml.min-1 were had the highest concentrations.	Creatinine	15-25	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
2344861-6	1990	The elimination half-life of benazeprilat during the first 24 h after dosing in the elderly was increased by about 20% to 3.2 h. The renal plasma clearance of benazeprilat (18.1 ml.min-1) was about 20% smaller than in the young subjects.	benazeprilat	29-41	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
2344861-6	1990	The elimination half-life of benazeprilat during the first 24 h after dosing in the elderly was increased by about 20% to 3.2 h. The renal plasma clearance of benazeprilat (18.1 ml.min-1) was about 20% smaller than in the young subjects.	benazeprilat	159-171	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
2347318-4	1990	After the fifth stage, peak oxygen consumption was determined by having the subject work against a resistance of 14.7-19.6 N at 30 rev.min-1.	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
2369910-6	1990	Alcohol induced a significant increase in heart rate during exercise at 50 W (delta x = 8 beats.min-1) and at 100 W (delta x = 10 beats.min-1), while the change at higher intensities was insignificant.	Alcohols	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
2369910-6	1990	Alcohol induced a significant increase in heart rate during exercise at 50 W (delta x = 8 beats.min-1) and at 100 W (delta x = 10 beats.min-1), while the change at higher intensities was insignificant.	Alcohols	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
2373126-3	1990	Hepatic blood flow was significantly increased by 1.2 and 0.41.min-1 after felodipine and nifedipine.	Felodipine	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
2373126-3	1990	Hepatic blood flow was significantly increased by 1.2 and 0.41.min-1 after felodipine and nifedipine.	Nifedipine	90-100	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
2373126-5	1990	The forearm blood flow was increased by about 30 ml.100 ml-1.min-1 after felodipine, but nifedipine had no effect.	Felodipine	73-83	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
2332544-2	1990	Amrinone was administered as a bolus of 1 mg kg-1 body wt., followed by continuous infusion at 10 micrograms kg-1 min-1 for 1 h and two stepwise increases to 20 and 40 micrograms kg-1 min-1 for 30 min each.	Amrinone	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
2332544-5	1990	Administration of amrinone lowered systemic vascular resistance from 20.0 +/- 4.3 to 16.5 +/- 4.6 mmHg l-1 min-1 m-2 (p less than 0.05) and reduced mean arterial pressure from 71.7 +/- 9.5 to 62.6 +/- 13.5 mmHg (p less than 0.05) at the highest infusion rate, confirming the known vasodilative effect of the drug.	Amrinone	18-26	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
2358560-4	1990	By contrast, a fentanyl-midazolam combination with continuous supplementation of clonidine 0.014 micrograms kg-1 min-1 (1.44 mg 70 kg-1 24 h-1) was very effective in terms of sedation and pain relief.	Clonidine	81-90	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
2358560-5	1990	During combined fentanyl-midazolam and clonidine infusion, cardiovascular depression gradually developed over several days necessitating the institution of a dobutamine infusion (dose: 8-12 micrograms kg-1 min-1).	Dobutamine	158-168	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
24047401-6	2013	AMP-activated protein kinase (AMPK) activators such as resveratrol, AICAR and metformin protected endothelial cells against complement-mediated cytotoxicity through the increase in CD55, CD59, haem oxygenase-1 (HO-1) and ferritin heavy chain (ferritin H) genes, all of which were attenuated by AMPKalpha knock-down.	Metformin	78-87	CD59 molecule (CD59 blood group)	Homo sapiens	187-191
24102663-7	2013	The median serum creatinine in pregnant women (46 micromol/L) was significantly lower and the median creatinine clearance (163 ml/min/1.73 m(2) ) was significantly higher than other groups (P &lt; 0.001 and P = 0.004, respectively).	Creatinine	101-111	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
9110952-12	1996	These rates amount to approximately 1000 ml O2 kg-1 min-1.	Oxygen	44-46	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
7988578-3	1994	Nitrous oxide administration for 5 min caused a decrease in mean arterial pressure from 82 +/- 10 to 71 +/- 12.7 mmHg (P &lt; 0.001), cardiac index (2.8 +/- 0.5 to 2.4 +/- 0.5 litres min-1 m-2, P &lt; 0.01), heart rate (104 +/- 17 to 99 +/- 18 beats min-1, P &lt; 0.05), left ventricular stroke work index (29.4 +/- 8.1 to 22 +/- 8.7 gm-m beat-1 mm-1, P &lt; 0.001), stroke volume (45.3 +/- 11.6 to 40 +/- 12.8 ml beat-1, P &lt; 0.05) and an increase in pulmonary vascular resistance from 106.4 +/- 53.9 to 143.9 +/- 81.0 dynes s cm-5 (P &lt; 0.01) and right atrial pressure (1.42 +/- 2.09 to 1.71 +/- 2.21 mmHg, P &lt; 0.05).	Nitrous Oxide	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
7988578-3	1994	Nitrous oxide administration for 5 min caused a decrease in mean arterial pressure from 82 +/- 10 to 71 +/- 12.7 mmHg (P &lt; 0.001), cardiac index (2.8 +/- 0.5 to 2.4 +/- 0.5 litres min-1 m-2, P &lt; 0.01), heart rate (104 +/- 17 to 99 +/- 18 beats min-1, P &lt; 0.05), left ventricular stroke work index (29.4 +/- 8.1 to 22 +/- 8.7 gm-m beat-1 mm-1, P &lt; 0.001), stroke volume (45.3 +/- 11.6 to 40 +/- 12.8 ml beat-1, P &lt; 0.05) and an increase in pulmonary vascular resistance from 106.4 +/- 53.9 to 143.9 +/- 81.0 dynes s cm-5 (P &lt; 0.01) and right atrial pressure (1.42 +/- 2.09 to 1.71 +/- 2.21 mmHg, P &lt; 0.05).	Nitrous Oxide	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	250-255
34954148-8	2022	The measurement of OAs" oxidative potential through dithiothreitol (DTT) assay has confirmed that as it had dropped from 0.88 nmol min-1 m-3 to 0.80 nmol min-1 m-3.	Dithiothreitol	52-66	CD59 molecule (CD59 blood group)	Homo sapiens	131-140
34814021-8	2022	In case of NaOH as the electrolyte, the single-pass nitrate removal efficiency, selectivity to nitrogen formation and nitrate removal rate was 90.66%, 96.40% and 1.47 x 10-3 mmol min-1 cm-2, respectively.	Sodium Hydroxide	11-15	CD59 molecule (CD59 blood group)	Homo sapiens	179-189
34814021-8	2022	In case of NaOH as the electrolyte, the single-pass nitrate removal efficiency, selectivity to nitrogen formation and nitrate removal rate was 90.66%, 96.40% and 1.47 x 10-3 mmol min-1 cm-2, respectively.	Nitrates	52-59	CD59 molecule (CD59 blood group)	Homo sapiens	179-189
34814021-8	2022	In case of NaOH as the electrolyte, the single-pass nitrate removal efficiency, selectivity to nitrogen formation and nitrate removal rate was 90.66%, 96.40% and 1.47 x 10-3 mmol min-1 cm-2, respectively.	Nitrogen	95-103	CD59 molecule (CD59 blood group)	Homo sapiens	179-189
34814021-8	2022	In case of NaOH as the electrolyte, the single-pass nitrate removal efficiency, selectivity to nitrogen formation and nitrate removal rate was 90.66%, 96.40% and 1.47 x 10-3 mmol min-1 cm-2, respectively.	Nitrates	118-125	CD59 molecule (CD59 blood group)	Homo sapiens	179-189
34956875-10	2021	Results: We demonstrated that herbal (curcumin and perillyl alcohol) blockade of NF-kappaB specifically suppresses the expression of inducible CD59 but not CD20, thus sensitizing resistant cells to rituximab-mediated CDC.	Curcumin	38-46	CD59 molecule (CD59 blood group)	Homo sapiens	143-147
34952902-6	2021	The rate constant was found to be 0.244 min-1 and 2.31 x 10-2 min-1 for sarin and soman, respectively over Zr(OH)4@W-ACF.	Sarin	72-77	CD59 molecule (CD59 blood group)	Homo sapiens	40-51
34952902-6	2021	The rate constant was found to be 0.244 min-1 and 2.31 x 10-2 min-1 for sarin and soman, respectively over Zr(OH)4@W-ACF.	Soman	82-87	CD59 molecule (CD59 blood group)	Homo sapiens	40-51
34952902-6	2021	The rate constant was found to be 0.244 min-1 and 2.31 x 10-2 min-1 for sarin and soman, respectively over Zr(OH)4@W-ACF.	zr(oh)4	107-114	CD59 molecule (CD59 blood group)	Homo sapiens	40-51
34956875-10	2021	Results: We demonstrated that herbal (curcumin and perillyl alcohol) blockade of NF-kappaB specifically suppresses the expression of inducible CD59 but not CD20, thus sensitizing resistant cells to rituximab-mediated CDC.	perillyl alcohol	51-67	CD59 molecule (CD59 blood group)	Homo sapiens	143-147
34838781-7	2022	The corresponding diffusion coefficient and kinetic rate were 9.1 x 10-7 cm2 min-1 and 6.51 x 10-7 min-1, which were used as controlled release to achieve the desired curcumin constant release rate in the delivery system.	Curcumin	167-175	CD59 molecule (CD59 blood group)	Homo sapiens	77-88
34759020-4	2022	RESULTS: iPSC-derived MNs moderately express the complement regulatory proteins CD46 and CD55 and strongly expressed CD59.	Manganese	22-25	CD59 molecule (CD59 blood group)	Homo sapiens	117-121
34771354-6	2021	Following the pseudo-first-order kinetics, 5 mg of the catalyst led to a 90% conversion of 4-NP with the mass-normalized rate constant (km1) of 6.94 x 10-3 min-1 mg-1, while the corresponding value acquired for 4-NA was 7.2 x 10-3 min-1 mg-1, despite the trace amount of Re in the heterogenous catalyst.	4-nitroaniline	211-215	CD59 molecule (CD59 blood group)	Homo sapiens	231-241
34392079-4	2021	In a 1-M urea solution, the maximum velocity (Vmax) of laccase was estimated to be 39.1 mumol min-1 mg-1.	Urea	9-13	CD59 molecule (CD59 blood group)	Homo sapiens	94-104
34392079-5	2021	This value was improved to 101.7 and 51.8 mumol min-1 mg-1 in the presence of sorbitol and proline, respectively.	Sorbitol	78-86	CD59 molecule (CD59 blood group)	Homo sapiens	48-58
34392079-5	2021	This value was improved to 101.7 and 51.8 mumol min-1 mg-1 in the presence of sorbitol and proline, respectively.	Proline	91-98	CD59 molecule (CD59 blood group)	Homo sapiens	48-58
34107511-8	2021	VO2peak decreased from 35+-6 to 31+-6 ml min-1 kg-1, P<0.001) in women and from 35+-9 to 32+-9 ml min-1 kg-1 (P=0.024) in men in approximate proportion to the reduction of O2 carrying capacity, an effect that did not differ between sexes (P=0.778).	Oxygen	172-174	CD59 molecule (CD59 blood group)	Homo sapiens	41-51
34107511-8	2021	VO2peak decreased from 35+-6 to 31+-6 ml min-1 kg-1, P<0.001) in women and from 35+-9 to 32+-9 ml min-1 kg-1 (P=0.024) in men in approximate proportion to the reduction of O2 carrying capacity, an effect that did not differ between sexes (P=0.778).	Oxygen	172-174	CD59 molecule (CD59 blood group)	Homo sapiens	98-108
34715525-7	2021	The bioinspired material exhibited an efficient water collection rate (WCR) of 14.9 +- 0.2 mg min-1 cm-2, which was 5.3 and 2.5 times larger than that on uniformed superhydrophilic and superhydrophobic surfaces, respectively.	Water	48-53	CD59 molecule (CD59 blood group)	Homo sapiens	94-104
34771307-5	2021	The increased photocatalytic efficiency, with respect to the bulk material, is underlined by the calculation of the kinetic constant of the photoreduction process (2.78 x 10-1 min-1 and 3.54 x 10-3 min-1) for pePhCN and bulk PhCN, respectively.	pephcn	209-215	CD59 molecule (CD59 blood group)	Homo sapiens	176-187
35456697-6	2022	The rate of metronidazole release from the floating tablets (K = 6.278 mg min-1/2) was significantly lower than that from conventional tablets (K = 10.666 mg min-1/2), indicating sustained drug release, according to the Higuchi model, for more than 6 h in an acidic medium of 0.1 N HCl.	Metronidazole	12-25	CD59 molecule (CD59 blood group)	Homo sapiens	74-81
34524975-0	2021	Plasma glycated CD59 predicts postpartum glucose intolerance after gestational diabetes.	Glucose	41-48	CD59 molecule (CD59 blood group)	Homo sapiens	16-20
34524975-1	2021	AIMS: To assess whether in women with gestational diabetes mellitus (GDM), postpartum plasma glycated CD59 (pGCD59) levels predict conversion to glucose intolerance diagnosed with an oral glucose tolerance test (OGTT).	Glucose	145-152	CD59 molecule (CD59 blood group)	Homo sapiens	102-106
34524975-1	2021	AIMS: To assess whether in women with gestational diabetes mellitus (GDM), postpartum plasma glycated CD59 (pGCD59) levels predict conversion to glucose intolerance diagnosed with an oral glucose tolerance test (OGTT).	Glucose	188-195	CD59 molecule (CD59 blood group)	Homo sapiens	102-106
34303967-0	2021	SPPL3-dependent downregulation of the synthesis of (neo)lacto-series glycosphingolipid is required for the staining of cell surface CD59.	(neo)lacto-series glycosphingolipid	51-86	CD59 molecule (CD59 blood group)	Homo sapiens	132-136
34303967-1	2021	CD59 is a small glycoprotein modified with a glycophosphatidylinositol (GPI) anchor that prevents the formation of the membrane attack complex, thereby protecting host cells from lysis.	glycophosphatidylinositol	45-70	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
34303967-1	2021	CD59 is a small glycoprotein modified with a glycophosphatidylinositol (GPI) anchor that prevents the formation of the membrane attack complex, thereby protecting host cells from lysis.	GPI 1046	72-75	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
34303967-5	2021	Surface CD59 staining requires the intramembrane protease activity of SPPL3 and SPPL3-mediated suppression of the (neo)lacto-series glycosphingolipids (nsGSLs)-but not N-glycan-synthesis pathway.	neo)lacto-series glycosphingolipids	115-150	CD59 molecule (CD59 blood group)	Homo sapiens	8-12
34303967-5	2021	Surface CD59 staining requires the intramembrane protease activity of SPPL3 and SPPL3-mediated suppression of the (neo)lacto-series glycosphingolipids (nsGSLs)-but not N-glycan-synthesis pathway.	nsgsls	152-158	CD59 molecule (CD59 blood group)	Homo sapiens	8-12
34603086-2	2021	Methods: Training data from 19 high-level rowers (age 23.5 +- 5.9 years; maximal oxygen uptake 58.9 +- 5.8 ml min-1 kg-1) were collected during a 4-week volume increased training period.	Oxygen	81-87	CD59 molecule (CD59 blood group)	Homo sapiens	110-120
34135326-5	2021	The structure of the ceramide acyl chain still affects these domains, as co-clustering with the glycosylphosphatidylinositol (GPI)-anchored protein CD59 occurs only when GM1 contains the fully saturated C16:0 acyl chain, and not C16:1.	Ceramides	21-29	CD59 molecule (CD59 blood group)	Homo sapiens	148-152
34135326-5	2021	The structure of the ceramide acyl chain still affects these domains, as co-clustering with the glycosylphosphatidylinositol (GPI)-anchored protein CD59 occurs only when GM1 contains the fully saturated C16:0 acyl chain, and not C16:1.	G(M1) Ganglioside	170-173	CD59 molecule (CD59 blood group)	Homo sapiens	148-152
35398811-6	2022	The in vitro heat transfer experiment showed that the BHE efficiently cooled the simulated blood from the initial 37  C-5.8  C within 150 s by using cold water (200 ml min-1, 0  C).	Water	154-159	CD59 molecule (CD59 blood group)	Homo sapiens	168-179
35603428-6	2022	We find that CD59, a GPI-AP, is attached via EthN-P-Man2 both in PIGB-knockout cells, in which GPI lacks Man3, and with a small fraction in wild-type cells.	ethn-p-man2	45-56	CD59 molecule (CD59 blood group)	Homo sapiens	13-17
35063431-5	2022	The desalination rate of Z3 in the SCC mode was improved with flow rates and influent salt concentrations increase, reaching 0.278 mg min-1 cm-2 under a continuous operation.	Salts	86-90	CD59 molecule (CD59 blood group)	Homo sapiens	134-144
35456697-6	2022	The rate of metronidazole release from the floating tablets (K = 6.278 mg min-1/2) was significantly lower than that from conventional tablets (K = 10.666 mg min-1/2), indicating sustained drug release, according to the Higuchi model, for more than 6 h in an acidic medium of 0.1 N HCl.	Metronidazole	12-25	CD59 molecule (CD59 blood group)	Homo sapiens	158-165
35387305-0	2022	Preparation of Novel ICT-CMC-CD59sp Drug-Loaded Microspheres and Targeting Anti-Tumor Effect on Oral Squamous Cell Carcinoma.	carboxymethyl-chitosan	25-28	CD59 molecule (CD59 blood group)	Homo sapiens	29-33
35387305-2	2022	In this study, a novel microsphere (ICT-CMC-CD59sp) composed of icariin (ICT), carboxymethyl chitosan (CMC), and cell differentiation antigen 59-specific ligand peptide (CD59sp) was successfully prepared by using the emulsion cross-linking method.	carboxymethyl-chitosan	103-106	CD59 molecule (CD59 blood group)	Homo sapiens	44-48
2611066-3	1989	Laudanosine T1/2 beta was also significantly longer (229.1 v. 173.1 min) and the clearance significantly slower (4.85 v. 7.29 ml min-1 kg-1) in the elderly.	laudanosine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	129-139
35322014-6	2022	The optimized photoanode based on hematite mesocrystals with oxide overlayers containing Sn and Ti dopants realises high activity (~0.8 mumol min-1 cm-2) and selectivity (~90%) for photoelectrochemical H2O2 production, which provides a wide range of application for the proposed concept.	photoanode	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	142-152
35322014-6	2022	The optimized photoanode based on hematite mesocrystals with oxide overlayers containing Sn and Ti dopants realises high activity (~0.8 mumol min-1 cm-2) and selectivity (~90%) for photoelectrochemical H2O2 production, which provides a wide range of application for the proposed concept.	Tin	89-91	CD59 molecule (CD59 blood group)	Homo sapiens	142-152
2611067-2	1989	Propofol was distributed rapidly and extensively (Vss 10.9 (1.2) litre kg-1) and cleared rapidly from the body (Cl 30.6 (2.9) ml min-1 kg-1).	Propofol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	129-139
2532922-9	1989	Fenoterol also caused a mean increase of 8.7 beats min-1 in heart rate, 5 min after inhalation.	Fenoterol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
2558700-9	1989	Adrenaline infusion raised venous plasma adrenaline levels to 4-5 nmol l-1, increased heart rate by 14 +/- 3 beats min-1 and plasma cyclic AMP by 17 +/- 3 nmol l-1, and decreased diastolic blood pressure by 15 +/- 5 mm Hg.	Epinephrine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
2611089-4	1989	Under fasting conditions, ciprofibrate, was absorbed rapidly in subjects with normal renal function, and its apparent elimination half-life was approximately 81 h. Both renal clearance (0.15 ml min-1) and cumulative renal excretion (less than 7% of the administered dose) were low.	ciprofibrate	26-38	CD59 molecule (CD59 blood group)	Homo sapiens	194-199
2611089-10	1989	It is concluded that, from a pharmacokinetic point of view, a reduction in the dosage of ciprofibrate should be considered in patients with a glomerular filtration rate below 30 ml min-1/1.73 m2.	ciprofibrate	89-101	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
2620324-6	1989	L-NMMA (100 nmol.min-1) stereospecifically inhibited vasodilatation induced by acetylcholine and bradykinin (p less than 0.02) but not that induced by the endothelium independent vasodilator glyceryl trinitrate.	N(G)-monomethylarginine acetate	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	17-22
2620324-6	1989	L-NMMA (100 nmol.min-1) stereospecifically inhibited vasodilatation induced by acetylcholine and bradykinin (p less than 0.02) but not that induced by the endothelium independent vasodilator glyceryl trinitrate.	Acetylcholine	79-92	CD59 molecule (CD59 blood group)	Homo sapiens	17-22
2620324-6	1989	L-NMMA (100 nmol.min-1) stereospecifically inhibited vasodilatation induced by acetylcholine and bradykinin (p less than 0.02) but not that induced by the endothelium independent vasodilator glyceryl trinitrate.	Nitroglycerin	191-210	CD59 molecule (CD59 blood group)	Homo sapiens	17-22
2620324-7	1989	L-NMMA (100 nmol.min-1) potentiated the venoconstrictor effect of a high dose of acetylcholine (100 nmol.min-1) without affecting the action of noradrenaline and without having a direct venoconstrictor effect in doses up to 10 mumol.min-1.	N(G)-monomethylarginine acetate	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	17-22
2620324-7	1989	L-NMMA (100 nmol.min-1) potentiated the venoconstrictor effect of a high dose of acetylcholine (100 nmol.min-1) without affecting the action of noradrenaline and without having a direct venoconstrictor effect in doses up to 10 mumol.min-1.	N(G)-monomethylarginine acetate	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
2620324-7	1989	L-NMMA (100 nmol.min-1) potentiated the venoconstrictor effect of a high dose of acetylcholine (100 nmol.min-1) without affecting the action of noradrenaline and without having a direct venoconstrictor effect in doses up to 10 mumol.min-1.	N(G)-monomethylarginine acetate	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
2620324-7	1989	L-NMMA (100 nmol.min-1) potentiated the venoconstrictor effect of a high dose of acetylcholine (100 nmol.min-1) without affecting the action of noradrenaline and without having a direct venoconstrictor effect in doses up to 10 mumol.min-1.	Acetylcholine	81-94	CD59 molecule (CD59 blood group)	Homo sapiens	17-22
2620324-7	1989	L-NMMA (100 nmol.min-1) potentiated the venoconstrictor effect of a high dose of acetylcholine (100 nmol.min-1) without affecting the action of noradrenaline and without having a direct venoconstrictor effect in doses up to 10 mumol.min-1.	Acetylcholine	81-94	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
2620324-7	1989	L-NMMA (100 nmol.min-1) potentiated the venoconstrictor effect of a high dose of acetylcholine (100 nmol.min-1) without affecting the action of noradrenaline and without having a direct venoconstrictor effect in doses up to 10 mumol.min-1.	Acetylcholine	81-94	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
2613366-7	1989	Maximal oxygen uptake was significantly different between conditions: 72.0 +/- 5.4 ml kg-1 min-1 at 20 degrees C; 68.9 +/- 5.1 ml kg-1 min-1 at 0 degree C and 68.5 +/- 4.6 ml kg-1 min-1 at -20 degrees C. Workload, time to exhaustion, glucose levels and rectal temperature decreased significantly at -20 degrees C. Catecholamines and lactate values were not significantly altered by thermal conditions after maximal exercise but the catecholamines were decreased during rest.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
2613366-7	1989	Maximal oxygen uptake was significantly different between conditions: 72.0 +/- 5.4 ml kg-1 min-1 at 20 degrees C; 68.9 +/- 5.1 ml kg-1 min-1 at 0 degree C and 68.5 +/- 4.6 ml kg-1 min-1 at -20 degrees C. Workload, time to exhaustion, glucose levels and rectal temperature decreased significantly at -20 degrees C. Catecholamines and lactate values were not significantly altered by thermal conditions after maximal exercise but the catecholamines were decreased during rest.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
2613366-7	1989	Maximal oxygen uptake was significantly different between conditions: 72.0 +/- 5.4 ml kg-1 min-1 at 20 degrees C; 68.9 +/- 5.1 ml kg-1 min-1 at 0 degree C and 68.5 +/- 4.6 ml kg-1 min-1 at -20 degrees C. Workload, time to exhaustion, glucose levels and rectal temperature decreased significantly at -20 degrees C. Catecholamines and lactate values were not significantly altered by thermal conditions after maximal exercise but the catecholamines were decreased during rest.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
2515588-0	1989	Determination of 51Cr-EDTA clearance between 15 and 40 ml/min/1.73 m2 by a single plasma sample.	51cr-edta	17-26	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
2515588-1	1989	A single-sample method for calculation of 51Cr-EDTA clearance (Cl) between 15 and 40 ml/min/1.73 m2 (ClB) is introduced.	51cr-edta	42-51	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
2515588-1	1989	A single-sample method for calculation of 51Cr-EDTA clearance (Cl) between 15 and 40 ml/min/1.73 m2 (ClB) is introduced.	Chlorambucil	101-104	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
2611352-5	1989	10(3) degree min-1 inhibited salt precipitation which had been observed during slow cooling (0.62 degree min-1), without, however, affecting the shape of the ice melting endotherm.	Salts	29-33	CD59 molecule (CD59 blood group)	Homo sapiens	13-18
2611352-5	1989	10(3) degree min-1 inhibited salt precipitation which had been observed during slow cooling (0.62 degree min-1), without, however, affecting the shape of the ice melting endotherm.	Salts	29-33	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
2511912-7	1989	The oral clearance of R-flecainide (467 +/- 109 ml min-1) was less (P less than 0.03) than that of the S-enantiomer (620 +/- 172 ml min-1).	Flecainide	22-34	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
2590612-4	1989	This dose of aspirin caused more than a 5 fold increase in gastric bleeding, from control values of 0.5 microliters 10 min-1 (95% confidence limits 0.3-0.8 microliters 10 min-1) to 2.8 microliters 10 min-1 (1.9-4.1 microliters 10 min-1, P less than 0.01) after 5 days of aspirin.	Aspirin	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
2590612-4	1989	This dose of aspirin caused more than a 5 fold increase in gastric bleeding, from control values of 0.5 microliters 10 min-1 (95% confidence limits 0.3-0.8 microliters 10 min-1) to 2.8 microliters 10 min-1 (1.9-4.1 microliters 10 min-1, P less than 0.01) after 5 days of aspirin.	Aspirin	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
2590612-4	1989	This dose of aspirin caused more than a 5 fold increase in gastric bleeding, from control values of 0.5 microliters 10 min-1 (95% confidence limits 0.3-0.8 microliters 10 min-1) to 2.8 microliters 10 min-1 (1.9-4.1 microliters 10 min-1, P less than 0.01) after 5 days of aspirin.	Aspirin	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
2590612-4	1989	This dose of aspirin caused more than a 5 fold increase in gastric bleeding, from control values of 0.5 microliters 10 min-1 (95% confidence limits 0.3-0.8 microliters 10 min-1) to 2.8 microliters 10 min-1 (1.9-4.1 microliters 10 min-1, P less than 0.01) after 5 days of aspirin.	Aspirin	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
2590612-5	1989	Adaptation did not occur and the gastric bleeding rates remained elevated at 3.4 microliters 10 min-1 (1.9-6.1 microliters 10 min-1) after 12 days of aspirin consumption (P less than 0.01).	Aspirin	150-157	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
2590612-7	1989	Coadministration of ranitidine significantly raised intragastric pH and reduced aspirin induced bleeding to 1.5 microliters 10 min-1 (1.0-2.3 microliters 10 min-1) after 5 days and 1.6 (1.0-2.5 microliters 10 min-1) after 12 days (P less than 0.05).	Ranitidine	20-30	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
2590612-7	1989	Coadministration of ranitidine significantly raised intragastric pH and reduced aspirin induced bleeding to 1.5 microliters 10 min-1 (1.0-2.3 microliters 10 min-1) after 5 days and 1.6 (1.0-2.5 microliters 10 min-1) after 12 days (P less than 0.05).	Ranitidine	20-30	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
2590612-7	1989	Coadministration of ranitidine significantly raised intragastric pH and reduced aspirin induced bleeding to 1.5 microliters 10 min-1 (1.0-2.3 microliters 10 min-1) after 5 days and 1.6 (1.0-2.5 microliters 10 min-1) after 12 days (P less than 0.05).	Ranitidine	20-30	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
2590612-7	1989	Coadministration of ranitidine significantly raised intragastric pH and reduced aspirin induced bleeding to 1.5 microliters 10 min-1 (1.0-2.3 microliters 10 min-1) after 5 days and 1.6 (1.0-2.5 microliters 10 min-1) after 12 days (P less than 0.05).	Aspirin	80-87	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
2590614-4	1989	The mean plasma clearance of morphine was significantly higher in children than neonates (25.7 and 4.7 ml min-1 kg-1, respectively) (P less than 0.01).	Morphine	29-37	CD59 molecule (CD59 blood group)	Homo sapiens	106-116
2515969-4	1989	The effect of local infusions of acetylcholine (7-70 nmol min-1) on the vessel diameters was assessed by quantitative angiography.	Acetylcholine	33-46	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
2559850-5	1989	Despite these steady haemodynamic conditions, intracoronary enalaprilat provoked a significant elevation of coronary sinus blood flow (181 +/- 73 to 214 +/- 79 ml min-1, P less than 0.001) with a reduction of coronary resistance (0.51 +/- 0.17 to 0.41 +/- 0.15 mmHg ml-1 min, P less than 0.001), and no significant alteration in plasma renin activity or plasma aldosterone.	Enalaprilat	60-71	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
2620691-7	1989	With diatrizoate-76% coronary dilation at t0 averaged 18.9 +/- 6.7% (P less than 0.001); it correlated positively (P less than 0.001) with the number of diagnostic injections performed per min (mean 1.2 +/- 0.3 min-1), and negatively (P less than 0.5) with the time interval between the last diagnostic contrast injection and t0 (mean interval 73 +/- 35 s).	Diatrizoate	5-16	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
2478585-2	1989	Recently we isolated a membrane constituent from normal erythrocytes that inhibits CoFBb-initiated hemolysis, and this protein was designated membrane inhibitor of reactive lysis (MIRL).	cofbb	83-88	CD59 molecule (CD59 blood group)	Homo sapiens	142-178
2478585-2	1989	Recently we isolated a membrane constituent from normal erythrocytes that inhibits CoFBb-initiated hemolysis, and this protein was designated membrane inhibitor of reactive lysis (MIRL).	cofbb	83-88	CD59 molecule (CD59 blood group)	Homo sapiens	180-184
2682012-6	1989	Systemic oxygen uptake was significantly greater at 2.0 than 1.5 L.min-1 m-2 by 18 (7, 30) ml.min-1.m-2, whereas it was not significantly affected by change in flow character (-4[-16, 7] ml.min-1.min-2) or arterial pH (-2 [-12, 8] ml.min-1.m-2 per 0.1 pH unit).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
2682012-6	1989	Systemic oxygen uptake was significantly greater at 2.0 than 1.5 L.min-1 m-2 by 18 (7, 30) ml.min-1.m-2, whereas it was not significantly affected by change in flow character (-4[-16, 7] ml.min-1.min-2) or arterial pH (-2 [-12, 8] ml.min-1.m-2 per 0.1 pH unit).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
2682012-6	1989	Systemic oxygen uptake was significantly greater at 2.0 than 1.5 L.min-1 m-2 by 18 (7, 30) ml.min-1.m-2, whereas it was not significantly affected by change in flow character (-4[-16, 7] ml.min-1.min-2) or arterial pH (-2 [-12, 8] ml.min-1.m-2 per 0.1 pH unit).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
2682012-6	1989	Systemic oxygen uptake was significantly greater at 2.0 than 1.5 L.min-1 m-2 by 18 (7, 30) ml.min-1.m-2, whereas it was not significantly affected by change in flow character (-4[-16, 7] ml.min-1.min-2) or arterial pH (-2 [-12, 8] ml.min-1.m-2 per 0.1 pH unit).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	196-201
2682012-6	1989	Systemic oxygen uptake was significantly greater at 2.0 than 1.5 L.min-1 m-2 by 18 (7, 30) ml.min-1.m-2, whereas it was not significantly affected by change in flow character (-4[-16, 7] ml.min-1.min-2) or arterial pH (-2 [-12, 8] ml.min-1.m-2 per 0.1 pH unit).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
2682012-12	1989	A flow rate of 1.5 L.min-1.m-2 during cardiopulmonary bypass with moderate hypothermia results in a less than maximal systemic oxygen uptake.	Oxygen	127-133	CD59 molecule (CD59 blood group)	Homo sapiens	21-26
2803313-2	1989	Erythrocytes from a patient who is completely deficient in HRF20 were readily hemolyzed by homologous complement activated by sucrose or by acidification as in paroxysmal nocturnal hemoglobinuria (PNH).	Sucrose	126-133	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
2801916-3	1989	The rate of covalent DIDS binding under conditions of excess DIDS in solution that ensure a complete irreversible inhibition followed an exponential time course with a rate coefficient Kcov (min-1).	4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid	21-25	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
2801916-3	1989	The rate of covalent DIDS binding under conditions of excess DIDS in solution that ensure a complete irreversible inhibition followed an exponential time course with a rate coefficient Kcov (min-1).	4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid	61-65	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
2530998-5	1989	Mean infusion rate required to maintain twitch response at 5 +/- 4% control was 6.7 micrograms kg-1 min-1 for mivacurium and 6.3 micrograms kg-1 min-1 for atracurium.	Atracurium	155-165	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
2819330-11	1989	Ouabain treatment (100 microM; 10 min) of glands perfused with normal Krebs evoked a long lasting catecholamine release, which reached a plateau at about 36 min and amounted to 0.68 +/- 0.25 microgram 2 min-1 (n = 9).	Ouabain	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
2590599-6	1989	Cortisol 6 beta-hydroxylase activity increased from 15 +/- 6 pmol min-1 mg-1 in organ donors (considered as "control subjects") to 87 +/- 31 pmol min-1 mg-1 in rifampicin treated patients.	Rifampin	160-170	CD59 molecule (CD59 blood group)	Homo sapiens	146-156
2613745-5	1989	In the presence of H4 biopterin, the dissociation rate constant (k-1) decreases from 6.2 x 10(-3) min-1 to 3.0 x 10(-3) min-1 and the half-time for dissociation increases from 106.8 min to 218.0 min.	sapropterin	19-31	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
2582730-7	1989	adrenaline infusion (0.02 microgram min-1 kg-1 body weight).	Epinephrine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
2582730-9	1989	Whole body oxygen uptake, carbon dioxide production, heart rate and plasma concentrations of free fatty acids (FFA) increased while the mean arterial pressure decreased significantly in response to adrenaline infusion at 0.02 microgram kg-1 min-1 in both weight-losing and weight-stable patients.	Epinephrine	198-208	CD59 molecule (CD59 blood group)	Homo sapiens	241-246
2582730-10	1989	Adrenaline at 0.005 microgram kg-1 min-1 increased plasma FFA levels by 19% (P less than 0.05) in weight-losing patients while no significant alteration was observed in well-nourished patients.	Epinephrine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
2582730-11	1989	Adrenaline infusion at 0.02 microgram kg-1 min-1 decreased the mean arterial blood pressure and stimulated respiratory gas exchange and heart rate significantly more in weight-losing than in weight-stable patients.	Epinephrine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
2513204-5	1989	The rate of VT decreased from 214 +/- 49 beats min-1 during the control electrophysiologic study to 178 +/- 48 beats min-1 during flecainide (P less than 0.01).	Flecainide	130-140	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
2513204-8	1989	VT rate as well as VT morphology during the control study discriminated between responders and non-responders; 11% of patients with VT-rate less than or equal to 230 beats min-1 responded to oral flecainide compared with 31% with a VT rate greater than 230 beats min-1 at control.	Flecainide	196-206	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
2606909-5	1989	The carboxy-terminal sequence confirmed that MACIF is a glycosylphosphatidylinositol (GPI)-anchored protein.	Glycosylphosphatidylinositols	56-84	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
2606909-5	1989	The carboxy-terminal sequence confirmed that MACIF is a glycosylphosphatidylinositol (GPI)-anchored protein.	Glycosylphosphatidylinositols	86-89	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
2606912-4	1989	Endoglycosidase F digestion of MACIF decreased its molecular weight by about 6K on SDS-PAGE.	Sodium Dodecyl Sulfate	83-86	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
2606912-5	1989	On the other hand, endoglycosidase H, neuraminidase, or endo-alpha-N-acetylgalactosaminidase treatment had no effect on the molecular weight, indicating that MACIF has complex-type N-linked oligosaccharide chains, but no O-linked chain.	n-linked oligosaccharide	181-205	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
2613745-5	1989	In the presence of H4 biopterin, the dissociation rate constant (k-1) decreases from 6.2 x 10(-3) min-1 to 3.0 x 10(-3) min-1 and the half-time for dissociation increases from 106.8 min to 218.0 min.	sapropterin	19-31	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
2682205-8	1989	This pattern of inhibition (competitive-mixed noncompetitive) was again obtained in this study using a ribosomal complex [acetyl[3H]Phe-tRNA-poly(U)-ribosome] of low peptidyltransferase activity (kcat = 0.91 min-1), as was obtained previously when we used a complex of high activity (kcat = 2.00 min-1).	Tritium	129-131	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
2682205-8	1989	This pattern of inhibition (competitive-mixed noncompetitive) was again obtained in this study using a ribosomal complex [acetyl[3H]Phe-tRNA-poly(U)-ribosome] of low peptidyltransferase activity (kcat = 0.91 min-1), as was obtained previously when we used a complex of high activity (kcat = 2.00 min-1).	Tritium	129-131	CD59 molecule (CD59 blood group)	Homo sapiens	296-301
2682205-9	1989	Thus, the lowering of the kcat of peptidyltransferase induced by chloramphenicol (from 0.91 to 0.34 min-1) can occur irrespective of the activity status of peptidyltransferase.	Chloramphenicol	65-80	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
2679978-7	1989	Forty-five patients were infused dobutamine 7 micrograms.kg-1.min-1 (group D) from 10 min.	Dobutamine	33-43	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
2679978-13	1989	With dobutamine, haemodynamic parameters returned to preoperative values and heart rate increased by 12 b.min-1.	Dobutamine	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
2803895-3	1989	Propofol 100 micrograms kg-1 min-1 and nitrous oxide in oxygen anaesthesia induced a significant decrease in amplitude of the SSEP; noxious stimulation resulted in an increase in afferent nerve transmission and a concomitant increase of amplitude of the late evoked potential.	Propofol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
2789924-5	1989	The best fit to the data was obtained when drug clearance (1 h-1) was related linearly to creatinine clearance (proportionality constant: 0.059 +/- 0.002 x CLcr (ml min-1)) and initial volume of distribution (1) was related linearly to body weight (proportionality constant: 0.327 +/- 0.014 x body weight (kg)).	Creatinine	90-100	CD59 molecule (CD59 blood group)	Homo sapiens	165-171
2789927-2	1989	Continuous infusion of oxytocin (0.33 u min-1) accelerated gastric emptying of semisolid TC-99m labelled Chelex-100 resin/oatmeal in 10 healthy volunteers under basal conditions.	Technetium	89-95	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
2789927-2	1989	Continuous infusion of oxytocin (0.33 u min-1) accelerated gastric emptying of semisolid TC-99m labelled Chelex-100 resin/oatmeal in 10 healthy volunteers under basal conditions.	Chelex 100	105-115	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
2475570-4	1989	CD59 antigen was purified from human urine and erythrocyte stroma by affinity chromatography using the mAb YTH 53.1 immobilized on Sepharose, and, following transient expression of a human T cell cDNA library in COS cells, the corresponding cDNA also identified using the antibody.	Sepharose	131-140	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
2475570-5	1989	It was found that the CD59 antigen is a small protein (approximately 20 kD as judged by SDS-PAGE, 11.5 kD predicted from the isolated cDNA) sometimes associated with larger components (45 and 80 kD) in urine.	Sodium Dodecyl Sulfate	88-91	CD59 molecule (CD59 blood group)	Homo sapiens	22-26
2475570-7	1989	CD59 antigen was released from the surface of transfected COS cells by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor; it is therefore likely to be absent from the surface of affected erythrocytes in the disease paroxysmal nocturnal hemoglobinuria.	Phosphatidylinositols	71-91	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
2475570-7	1989	CD59 antigen was released from the surface of transfected COS cells by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor; it is therefore likely to be absent from the surface of affected erythrocytes in the disease paroxysmal nocturnal hemoglobinuria.	Glycolipids	187-197	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
2635250-3	1989	Creatinine clearance declined to 75% (88 ml.min-1) of the resting values for all three exercises.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
2635255-5	1989	Both diltiazem and atenolol significantly decreased heart rate at peak effort but the decrease was much more pronounced after atenolol (-52 b.min-1) than after diltiazem (-6 b.min-1).	Diltiazem	5-14	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
2635255-5	1989	Both diltiazem and atenolol significantly decreased heart rate at peak effort but the decrease was much more pronounced after atenolol (-52 b.min-1) than after diltiazem (-6 b.min-1).	Diltiazem	5-14	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
2635255-5	1989	Both diltiazem and atenolol significantly decreased heart rate at peak effort but the decrease was much more pronounced after atenolol (-52 b.min-1) than after diltiazem (-6 b.min-1).	Atenolol	19-27	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
2635255-5	1989	Both diltiazem and atenolol significantly decreased heart rate at peak effort but the decrease was much more pronounced after atenolol (-52 b.min-1) than after diltiazem (-6 b.min-1).	Atenolol	19-27	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
2635255-5	1989	Both diltiazem and atenolol significantly decreased heart rate at peak effort but the decrease was much more pronounced after atenolol (-52 b.min-1) than after diltiazem (-6 b.min-1).	Atenolol	126-134	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
2475111-2	1989	The amino acid sequence deduced from its coding base sequence resembles that of T cell activating protein, most conspicuously in cysteine residues, 10 out of 11 of which occupy identical positions in an overall sequence homology of 24.8%.	Cysteine	129-137	CD59 molecule (CD59 blood group)	Homo sapiens	80-105
2527131-3	1989	Urinary excretion of prostaglandin E2 fell from 885 +/- 160 to 345 +/- 115 pg min-1, and excretion of 6-keto-prostaglandin F1 alpha fell from 489 +/- 77 to 283 +/- 50 pg min-1.	Dinoprostone	21-37	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
2548549-5	1989	For a target T1 of 20% of control value, the mean block was 18.7 (SD 1.3) % of baseline T1 and the mean consumption of atracurium was 5.39 (SD 1.23) micrograms kg-1 min-1.	Atracurium	119-129	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
2775615-12	1989	In the presence of carbidopa, the plasma clearance of intravenous levodopa (50 mg) was reduced in both age groups but remained lower in the elderly (5.8 +/- 0.9 ml min-1 kg-1 compared with 9.3 +/- 1.0 ml min-1 kg-1; P less than 0.01).	Carbidopa	19-28	CD59 molecule (CD59 blood group)	Homo sapiens	164-174
2775615-12	1989	In the presence of carbidopa, the plasma clearance of intravenous levodopa (50 mg) was reduced in both age groups but remained lower in the elderly (5.8 +/- 0.9 ml min-1 kg-1 compared with 9.3 +/- 1.0 ml min-1 kg-1; P less than 0.01).	Carbidopa	19-28	CD59 molecule (CD59 blood group)	Homo sapiens	204-214
2775615-12	1989	In the presence of carbidopa, the plasma clearance of intravenous levodopa (50 mg) was reduced in both age groups but remained lower in the elderly (5.8 +/- 0.9 ml min-1 kg-1 compared with 9.3 +/- 1.0 ml min-1 kg-1; P less than 0.01).	Levodopa	66-74	CD59 molecule (CD59 blood group)	Homo sapiens	164-174
2775615-12	1989	In the presence of carbidopa, the plasma clearance of intravenous levodopa (50 mg) was reduced in both age groups but remained lower in the elderly (5.8 +/- 0.9 ml min-1 kg-1 compared with 9.3 +/- 1.0 ml min-1 kg-1; P less than 0.01).	Levodopa	66-74	CD59 molecule (CD59 blood group)	Homo sapiens	204-214
2789070-7	1989	Aspirin increased bleeding from a rate on placebo of 1.2 microliters 10 min-1 geometric mean (95% confidence limits) (0.7-1.8) microliters 10 min-1 to 20.0 (11.6-34.2) microliters 10 min-1, (P less than 0.01).	Aspirin	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
2789070-7	1989	Aspirin increased bleeding from a rate on placebo of 1.2 microliters 10 min-1 geometric mean (95% confidence limits) (0.7-1.8) microliters 10 min-1 to 20.0 (11.6-34.2) microliters 10 min-1, (P less than 0.01).	Aspirin	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
2789070-7	1989	Aspirin increased bleeding from a rate on placebo of 1.2 microliters 10 min-1 geometric mean (95% confidence limits) (0.7-1.8) microliters 10 min-1 to 20.0 (11.6-34.2) microliters 10 min-1, (P less than 0.01).	Aspirin	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
2789070-8	1989	The rate of bleeding after aspirin preceded by ethamsylate [14.1 (8.5-23.4) microliters 10 min-1] was not significantly different from that after aspirin alone.	Aspirin	27-34	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
2789070-8	1989	The rate of bleeding after aspirin preceded by ethamsylate [14.1 (8.5-23.4) microliters 10 min-1] was not significantly different from that after aspirin alone.	Ethamsylate	47-58	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
2503289-10	1989	Efflux of 3-methylhistidine significantly (P less than 0.05) decreased from the leg in those subjects who performed daily exercise (-0.29 +/- 0.12 nmol min-1 100 ml-1 of tissue) compared with those subjects receiving IVF without daily exercise (-1.46 +/- 0.35 nmol min-1 100 ml-1 of tissue).	3-methylhistidine	10-27	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
2503289-10	1989	Efflux of 3-methylhistidine significantly (P less than 0.05) decreased from the leg in those subjects who performed daily exercise (-0.29 +/- 0.12 nmol min-1 100 ml-1 of tissue) compared with those subjects receiving IVF without daily exercise (-1.46 +/- 0.35 nmol min-1 100 ml-1 of tissue).	3-methylhistidine	10-27	CD59 molecule (CD59 blood group)	Homo sapiens	265-270
2503375-6	1989	Values for pharmacokinetic parameters of alfentanil were as follows: clearance, 5.2 +/- 2.0 ml kg-1 min-1; volume of distribution, 0.63 +/- 0.20 1 kg-1; and elimination half-life, 96.9 +/- 52.5 min.	Alfentanil	41-51	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
2547642-8	1989	Adding amiloride to resting cells caused a slow, reversible acidification (0.04 pH units min-1).	Amiloride	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
2500510-5	1989	With glucose loading, infants with bronchopulmonary dysplasia had a significant rise in basal oxygen consumption (7.91 +/- 0.91 ml.kg-1.min-1 to 9.65 +/- 1.35 ml.kg-1.min-1, p less than 0.05), basal carbon dioxide production (5.93 +/- 0.72 ml.kg-1.min-1 to 7.10 +/- 1.04 ml.kg-1.min-1), and resting energy expenditure (53.8 +/- 5.75 kcal.kg-1.24 hr-1 to 65.3 +/- 7.0 kcal.kg-1.24 hr-1, all p values less than 0.05).	Glucose	5-12	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
2500510-5	1989	With glucose loading, infants with bronchopulmonary dysplasia had a significant rise in basal oxygen consumption (7.91 +/- 0.91 ml.kg-1.min-1 to 9.65 +/- 1.35 ml.kg-1.min-1, p less than 0.05), basal carbon dioxide production (5.93 +/- 0.72 ml.kg-1.min-1 to 7.10 +/- 1.04 ml.kg-1.min-1), and resting energy expenditure (53.8 +/- 5.75 kcal.kg-1.24 hr-1 to 65.3 +/- 7.0 kcal.kg-1.24 hr-1, all p values less than 0.05).	Glucose	5-12	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
2500510-5	1989	With glucose loading, infants with bronchopulmonary dysplasia had a significant rise in basal oxygen consumption (7.91 +/- 0.91 ml.kg-1.min-1 to 9.65 +/- 1.35 ml.kg-1.min-1, p less than 0.05), basal carbon dioxide production (5.93 +/- 0.72 ml.kg-1.min-1 to 7.10 +/- 1.04 ml.kg-1.min-1), and resting energy expenditure (53.8 +/- 5.75 kcal.kg-1.24 hr-1 to 65.3 +/- 7.0 kcal.kg-1.24 hr-1, all p values less than 0.05).	Glucose	5-12	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
2500510-5	1989	With glucose loading, infants with bronchopulmonary dysplasia had a significant rise in basal oxygen consumption (7.91 +/- 0.91 ml.kg-1.min-1 to 9.65 +/- 1.35 ml.kg-1.min-1, p less than 0.05), basal carbon dioxide production (5.93 +/- 0.72 ml.kg-1.min-1 to 7.10 +/- 1.04 ml.kg-1.min-1), and resting energy expenditure (53.8 +/- 5.75 kcal.kg-1.24 hr-1 to 65.3 +/- 7.0 kcal.kg-1.24 hr-1, all p values less than 0.05).	Glucose	5-12	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
2500510-5	1989	With glucose loading, infants with bronchopulmonary dysplasia had a significant rise in basal oxygen consumption (7.91 +/- 0.91 ml.kg-1.min-1 to 9.65 +/- 1.35 ml.kg-1.min-1, p less than 0.05), basal carbon dioxide production (5.93 +/- 0.72 ml.kg-1.min-1 to 7.10 +/- 1.04 ml.kg-1.min-1), and resting energy expenditure (53.8 +/- 5.75 kcal.kg-1.24 hr-1 to 65.3 +/- 7.0 kcal.kg-1.24 hr-1, all p values less than 0.05).	Oxygen	94-100	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
2500510-5	1989	With glucose loading, infants with bronchopulmonary dysplasia had a significant rise in basal oxygen consumption (7.91 +/- 0.91 ml.kg-1.min-1 to 9.65 +/- 1.35 ml.kg-1.min-1, p less than 0.05), basal carbon dioxide production (5.93 +/- 0.72 ml.kg-1.min-1 to 7.10 +/- 1.04 ml.kg-1.min-1), and resting energy expenditure (53.8 +/- 5.75 kcal.kg-1.24 hr-1 to 65.3 +/- 7.0 kcal.kg-1.24 hr-1, all p values less than 0.05).	Oxygen	94-100	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
2500510-5	1989	With glucose loading, infants with bronchopulmonary dysplasia had a significant rise in basal oxygen consumption (7.91 +/- 0.91 ml.kg-1.min-1 to 9.65 +/- 1.35 ml.kg-1.min-1, p less than 0.05), basal carbon dioxide production (5.93 +/- 0.72 ml.kg-1.min-1 to 7.10 +/- 1.04 ml.kg-1.min-1), and resting energy expenditure (53.8 +/- 5.75 kcal.kg-1.24 hr-1 to 65.3 +/- 7.0 kcal.kg-1.24 hr-1, all p values less than 0.05).	Oxygen	94-100	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
2500510-5	1989	With glucose loading, infants with bronchopulmonary dysplasia had a significant rise in basal oxygen consumption (7.91 +/- 0.91 ml.kg-1.min-1 to 9.65 +/- 1.35 ml.kg-1.min-1, p less than 0.05), basal carbon dioxide production (5.93 +/- 0.72 ml.kg-1.min-1 to 7.10 +/- 1.04 ml.kg-1.min-1), and resting energy expenditure (53.8 +/- 5.75 kcal.kg-1.24 hr-1 to 65.3 +/- 7.0 kcal.kg-1.24 hr-1, all p values less than 0.05).	Oxygen	94-100	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
2742889-3	1989	The time-dependent photodynamic enhancement of leaks for K+ as well as choline or erythritol was paralleled by a marked increase of the transbilayer reorientation rate of the amphiphilic lipid probe, palmitoyllysophosphatidylcholine from 0.05% min-1 in native cells to 0.32% min-1 after 60 min illumination.	We 201	200-232	CD59 molecule (CD59 blood group)	Homo sapiens	244-249
2742889-3	1989	The time-dependent photodynamic enhancement of leaks for K+ as well as choline or erythritol was paralleled by a marked increase of the transbilayer reorientation rate of the amphiphilic lipid probe, palmitoyllysophosphatidylcholine from 0.05% min-1 in native cells to 0.32% min-1 after 60 min illumination.	We 201	200-232	CD59 molecule (CD59 blood group)	Homo sapiens	275-280
2757892-9	1989	Glyceryl trinitrate (0.4 microgram min-1) however, completely reversed the constriction to noradrenaline (P less than 0.001).	Nitroglycerin	0-19	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
2757892-9	1989	Glyceryl trinitrate (0.4 microgram min-1) however, completely reversed the constriction to noradrenaline (P less than 0.001).	Norepinephrine	91-104	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
2765696-1	1989	The glucuronide of N-1-hydroxy-ethyl flurazepam has been analysed by a direct liquid inlet liquid chromatographic/mass spectrometric system using MeOH/H2O (70:30 v/v) as mobile phase, at a flow rate of 0.7 ml min-1.	Glucuronides	4-15	CD59 molecule (CD59 blood group)	Homo sapiens	209-214
2765696-1	1989	The glucuronide of N-1-hydroxy-ethyl flurazepam has been analysed by a direct liquid inlet liquid chromatographic/mass spectrometric system using MeOH/H2O (70:30 v/v) as mobile phase, at a flow rate of 0.7 ml min-1.	n-1-hydroxy-ethyl flurazepam	19-47	CD59 molecule (CD59 blood group)	Homo sapiens	209-214
2775040-7	1989	All patients experienced some impairment in renal function with mean creatinine clearance decreasing from 129 +/- 19 to 91 +/- 13 ml/min/1.73m2 (p less than 0.05).	Creatinine	69-79	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
2590921-2	1989	We therefore infused six patients, catheterised for coronary angiography, with inosine (5 mg.kg-1.min-1 intravenously) for 6 minutes.	Inosine	79-86	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
2656343-4	1989	However, under isotopic non-steady-state conditions, the isotopically determined Ra was significantly lower than the glucose infusion rate (11.5 +/- 1.3 vs. 13.7 +/- 1.5 mg.kg-1 fat-free mass.min-1, respectively, P less than .001), and the underestimation was related to the deviation from the isotopic steady state.	Radium	81-83	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
2806500-5	1989	Indeed, since the oxygen flow rate cannot be reliably increased over 3 l.min-1 with the available oxygen concentrators, the reservoir device could be more effective in some selected patients whose hypoxaemia cannot be adequately corrected by standard nasal prongs.	Oxygen	18-24	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
2806500-5	1989	Indeed, since the oxygen flow rate cannot be reliably increased over 3 l.min-1 with the available oxygen concentrators, the reservoir device could be more effective in some selected patients whose hypoxaemia cannot be adequately corrected by standard nasal prongs.	Oxygen	98-104	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
2527155-3	1989	For a mean peak dose of 115 micrograms min-1 nitroprusside, cardiac index increased from 1.8 +/- 0.4 to 2.0 +/- 0.4 l min-1 m-2, while pulmonary artery diastolic pressure and mean right atrial pressure decreased from 29 +/- 6 to 24 +/- 5 and from 15 +/- 6 to 11 +/- 3 mmHg respectively; mean arterial pressure and heart rate were unchanged.	Nitroprusside	45-58	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
2527155-3	1989	For a mean peak dose of 115 micrograms min-1 nitroprusside, cardiac index increased from 1.8 +/- 0.4 to 2.0 +/- 0.4 l min-1 m-2, while pulmonary artery diastolic pressure and mean right atrial pressure decreased from 29 +/- 6 to 24 +/- 5 and from 15 +/- 6 to 11 +/- 3 mmHg respectively; mean arterial pressure and heart rate were unchanged.	Nitroprusside	45-58	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
2527155-5	1989	to nitroprusside resulted in a substantial improvement of cardiac function: cardiac index increased further to 2.8 +/- 0.5 l min-1 m-2 (P less than 0.001), pulmonary artery diastolic pressure and right atrial pressure decreased to 18 +/- 5 and 7 +/- 3 mmHg (P less than 0.01), respectively, while mean arterial pressure rose from 90 +/- 11 mmHg to 95 +/- 0 mmHg (P less than 0.05); heart rate was unchanged.	Nitroprusside	3-16	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
2625536-2	1989	SR125 was significantly correlated not only to predicted VO2max but also score (X) in the step test for 2 min (25 steps.min-1 on 35-cm stool), yielding a formula, SR125 = -0.00131X + 0.3660.	sr125	0-5	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
2625536-2	1989	SR125 was significantly correlated not only to predicted VO2max but also score (X) in the step test for 2 min (25 steps.min-1 on 35-cm stool), yielding a formula, SR125 = -0.00131X + 0.3660.	sr125	163-168	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
2656961-6	1989	For children whose initial creatinine clearance was less than 100 ml/min/1.75 m2, creatinine clearance also improved significantly (57.5 +/- 11 to 121 +/- 24.5 ml/min/1.75 m2; p less than 0.05).	Creatinine	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
2600859-5	1989	With tubocurarine, larger increases in mean arterial pressure of 11 mmHg and for heart rate of 8 beats min-1 were obtained during maintained contractions, and 15 mmHg and 16 beats min-1, respectively, during non-maintained contractions.	Tubocurarine	5-17	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
2600859-7	1989	Atropine increased resting heart rate and blood pressure with tubocurarine to 107 beats min-1 and 98 mmHg, respectively, in seven subjects.	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
2600859-7	1989	Atropine increased resting heart rate and blood pressure with tubocurarine to 107 beats min-1 and 98 mmHg, respectively, in seven subjects.	Tubocurarine	62-74	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
2600859-10	1989	Propranolol reduced resting heart rate with tubocurarine to 56 beats min-1 with no effect on blood pressure in seven subjects.	Propranolol	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
2677433-8	1989	During the surgery, ventilation was controlled, and phenylephrine was infused at the rate of 5-15 micrograms.min-1 to maintain systolic blood pressure above 100 mmHg.	Phenylephrine	52-65	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
2548573-1	1989	With proton nuclear magnetic resonance spectroscopy at 22 degrees C and pD 4.5, individual exchange rates in the range from 2 X 10(-5) to 1 X 10(-1) min-1 were observed for 23 amide protons in recombinant desulfatohirudin.	Amides	176-181	CD59 molecule (CD59 blood group)	Homo sapiens	149-154
2773665-7	1989	Infusion of nitroprusside at a dose lowering the mean blood pressure by 11.6 +/- 1.6 mmHg and increasing the heart rate to 74.6 +/- 2.9 beats min-1 elevated plasma noradrenaline to 2.86 +/- 0.39 nM.	Nitroprusside	12-25	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
2773665-7	1989	Infusion of nitroprusside at a dose lowering the mean blood pressure by 11.6 +/- 1.6 mmHg and increasing the heart rate to 74.6 +/- 2.9 beats min-1 elevated plasma noradrenaline to 2.86 +/- 0.39 nM.	Norepinephrine	164-177	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
2773665-9	1989	Infusion of nitroprusside at a rate lowering the blood pressure by 11.2 +/- 2.4 mmHg and increasing the heart rate to 74.4 +/- 0.5 beats min-1, elevated the plasma level of noradrenaline to 2.46 +/- 0.38 ng ml-1, which is not different from before ibuprofen.	Nitroprusside	12-25	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
2773665-9	1989	Infusion of nitroprusside at a rate lowering the blood pressure by 11.2 +/- 2.4 mmHg and increasing the heart rate to 74.4 +/- 0.5 beats min-1, elevated the plasma level of noradrenaline to 2.46 +/- 0.38 ng ml-1, which is not different from before ibuprofen.	Norepinephrine	173-186	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
2719238-6	1989	The mean FIO2 at a ventilation of 4.5 l.min-1 and 8 l.min-1 oxygen flow was 78% and this fell to 27% at a ventilation of 16 l.min-1 and oxygen flow of 2 l.min-1.	Oxygen	60-66	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
2719238-6	1989	The mean FIO2 at a ventilation of 4.5 l.min-1 and 8 l.min-1 oxygen flow was 78% and this fell to 27% at a ventilation of 16 l.min-1 and oxygen flow of 2 l.min-1.	Oxygen	60-66	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
2719238-6	1989	The mean FIO2 at a ventilation of 4.5 l.min-1 and 8 l.min-1 oxygen flow was 78% and this fell to 27% at a ventilation of 16 l.min-1 and oxygen flow of 2 l.min-1.	Oxygen	60-66	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
2525044-6	1989	The infusion rate required to maintain neuromuscular block was 88.6 (10.4) micrograms kg-1 min-1 for suxamethonium and 7.8 (1.2) micrograms kg-1 min-1 for mivacurium.	Mivacurium	155-165	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
2757879-5	1989	Exercise heart rates were 7% (+9.2 beats min-1) higher on flosequinan compared with placebo (P less than 0.05).	flosequinan	58-69	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
2757879-7	1989	As expected the heart rate on exercise was 25% less (-35 beats min-1) on propranolol (P less than 0.05).	Propranolol	73-84	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
2524341-6	1989	Glucose infusion requirements rose significantly during the exercise period from 2.8 +/- 0.5 mg kg-1 min-1 to a peak at 235 min of 11.1 +/- 1.2 mg kg-1 min-1 (p less than 0.001), compared with an increase on the control day from 2.0 +/- 0.6 to 2.5 +/- 0.6 mg kg-1 min-1 (NS) over the same period.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
2524341-6	1989	Glucose infusion requirements rose significantly during the exercise period from 2.8 +/- 0.5 mg kg-1 min-1 to a peak at 235 min of 11.1 +/- 1.2 mg kg-1 min-1 (p less than 0.001), compared with an increase on the control day from 2.0 +/- 0.6 to 2.5 +/- 0.6 mg kg-1 min-1 (NS) over the same period.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
2524341-6	1989	Glucose infusion requirements rose significantly during the exercise period from 2.8 +/- 0.5 mg kg-1 min-1 to a peak at 235 min of 11.1 +/- 1.2 mg kg-1 min-1 (p less than 0.001), compared with an increase on the control day from 2.0 +/- 0.6 to 2.5 +/- 0.6 mg kg-1 min-1 (NS) over the same period.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
2670657-7	1989	Sodium clearance decreased (from 1.4 +/- 0.6 to 1.1 +/- 0.5 ml/min 1.73 sqm with perindopril, p less than 0.05, and from 0.97 +/- 0.44 to 0.88 +/- 0.51 with captopril, n.s.).	Sodium	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
2557432-10	1989	Enalaprilat (13 nmol min-1) inhibited converting enzyme in the infused arm, in which it caused approximately a 100-fold reduction in sensitivity to angiotensin I, while having no effect on the vasoconstriction caused by angiotensin II.	Enalaprilat	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	21-26
2656961-6	1989	For children whose initial creatinine clearance was less than 100 ml/min/1.75 m2, creatinine clearance also improved significantly (57.5 +/- 11 to 121 +/- 24.5 ml/min/1.75 m2; p less than 0.05).	Creatinine	82-92	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
2498028-3	1989	In the present investigation the total plasma clearance of 51Cr-EDTA (ethylenediaminetetra-acetate) was assessed from 13 blood samples taken 5-300 min post-injection in 44 adult patients with GFR greater than 15 ml min-1.	51cr-edta	59-68	CD59 molecule (CD59 blood group)	Homo sapiens	215-220
2498028-7	1989	SEE of the five-samples method was 3.0 ml min-1 (EDTA) and 3.1 ml min-1 (DTPA).	Pentetic Acid	73-77	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
2656961-6	1989	For children whose initial creatinine clearance was less than 100 ml/min/1.75 m2, creatinine clearance also improved significantly (57.5 +/- 11 to 121 +/- 24.5 ml/min/1.75 m2; p less than 0.05).	Creatinine	82-92	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
2515277-3	1989	At rest CO2 was given at flow rates of 0.2 and 0.4 l min-1 and during exercise, to compensate for the smaller inhaled CO2 fraction as ventilation increased, at flow rates of 0.4 and 0.8 l min-1.	Carbon Dioxide	8-11	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
2568458-3	1989	Steady state flow was achieved for the mixture containing fine lactose which produced an extrudate of uniform moisture content at all extrusion rates except the lowest (5 cm min-1).	Lactose	63-70	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
2544086-6	1989	This reaction was first order in ICRF-187 and Fe3+-adriamycin and yielded a second order rate constant of 123 M-1 min-1.	fe3+-adriamycin	46-61	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
2657547-3	1989	The total dose and the mg min-1 dose of bupivacaine was significantly less following epinephrine-morphine pretreatment than the dose required when only bupivacaine was used for pain relief.	Bupivacaine	40-51	CD59 molecule (CD59 blood group)	Homo sapiens	26-31
2657547-3	1989	The total dose and the mg min-1 dose of bupivacaine was significantly less following epinephrine-morphine pretreatment than the dose required when only bupivacaine was used for pain relief.	Epinephrine	85-96	CD59 molecule (CD59 blood group)	Homo sapiens	26-31
2657547-3	1989	The total dose and the mg min-1 dose of bupivacaine was significantly less following epinephrine-morphine pretreatment than the dose required when only bupivacaine was used for pain relief.	Morphine	97-105	CD59 molecule (CD59 blood group)	Homo sapiens	26-31
2646944-5	1989	There was a positive correlation before training between maximum O2 uptake (Vo2 max) and total body glucose disposal rate (M) at the 40 mU.m-2.min-1 insulin infusion (r = 0.69, P less than 0.02).	Oxygen	65-67	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
2646944-5	1989	There was a positive correlation before training between maximum O2 uptake (Vo2 max) and total body glucose disposal rate (M) at the 40 mU.m-2.min-1 insulin infusion (r = 0.69, P less than 0.02).	Glucose	100-107	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
2495860-5	1989	Plasma clearance of alfentanil in young healthy subjects, 9.3 +/- 6.3 ml.kg-1.min-1, also showed an inverse relationship with age (r = -0.54, P less than 0.001), and was not affected by surgical stress in subjects older than 60 years.	Alfentanil	20-30	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
2565233-4	1989	Xamoterol produced significant improvements in resting cardiac index (2.51 +/- 0.15 to 2.80 +/- 0.14 l min-1 m-2; P less than 0.001), stroke volume (62 +/- 4 to 75 +/- 5 mljbeat-1; P less than 0.001) and stroke work index (42.4 +/- 3.6 to 47.7 +/- 3.9 gm beat-1 m-2; P less than 0.01).	Xamoterol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
2565233-7	1989	Xamoterol significantly attenuated the heart rate response to exercise (112 +/- 4 to 97 +/- 3 beats min-1; P less than 0.001), with no impairment in the expected exercise induced increase in cardiac index.	Xamoterol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
2539427-6	1989	The platelet noradrenaline efflux rate tended to be higher in patients with lower brake indices, a sign of autonomic neuropathy, than in controls (29.0 +/- 3.0 x 10(-3) min-1 vs. 21.2 +/- 0.9 x 10(-3) min-1; P less than 0.05).	Norepinephrine	13-26	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2539427-6	1989	The platelet noradrenaline efflux rate tended to be higher in patients with lower brake indices, a sign of autonomic neuropathy, than in controls (29.0 +/- 3.0 x 10(-3) min-1 vs. 21.2 +/- 0.9 x 10(-3) min-1; P less than 0.05).	Norepinephrine	13-26	CD59 molecule (CD59 blood group)	Homo sapiens	201-206
2564694-7	1989	Noradrenaline (100-1000 pmol kg-1 min-1 intravenously) increased rectal tone and anal canal pressure.	Norepinephrine	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	34-39
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	Phenylglyoxal	31-44	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	Arginine	4-12	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2665327-18	1989	The plasma clearance of fotemustine was 225 +/- 63 ml min-1 with a volume of distribution based on area of 4.1 +/- 1.2 litres.	fotemustine	24-35	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	Arginine	4-12	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	Arginine	4-12	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	Phenylglyoxal	31-44	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
2914947-6	1989	The second order rate constant for the process at 37 degrees C in the presence of 2 mM CaCl2 was 1.58 X 10(5) M-1.min-1.	Calcium Chloride	87-92	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	Phenylglyoxal	31-44	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	Diacetyl	46-61	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	Diacetyl	46-61	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	Diacetyl	46-61	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	1,2-cyclohexanedione	67-87	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	1,2-cyclohexanedione	67-87	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
2536743-2	1989	The arginine-specific reagents phenylglyoxal, 2,3-butanedione, and 1,2-cyclohexanedione all irreversibly inhibit the enzyme with second-order rate constants of 3.42 M-1 min-1, 3.13 M-1 min-1 and 0.313 M-1 min-1, respectively.	1,2-cyclohexanedione	67-87	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
2914965-10	1989	The apparent second-order rate constant of thrombin inhibition by heparin cofactor II increases from 4 x 10(4) (in the absence of fucoidan) to 1.5 x 10(8) M-1 min-1 as the fucoidan concentration increases from 0.1 to 10 micrograms/ml and then decreases as fucoidan is increased above 10 micrograms/ml.	fucoidan	172-180	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
2730221-3	1989	min and n = 450 and 800 min-1 were respectively the lower and the upper levels of the optimal conditions by oxygen mass transfer during amphotericin B biosynthesis.	Oxygen	108-114	CD59 molecule (CD59 blood group)	Homo sapiens	24-29
2563317-8	1989	Thirty-two per cent of patients receiving pancuronium received propranolol for heart rates greater than 90 beats.min-1 versus 7% of those who received vecuronium (P approximately 0.01).	Pancuronium	42-53	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
2563317-8	1989	Thirty-two per cent of patients receiving pancuronium received propranolol for heart rates greater than 90 beats.min-1 versus 7% of those who received vecuronium (P approximately 0.01).	Propranolol	63-74	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
2730221-3	1989	min and n = 450 and 800 min-1 were respectively the lower and the upper levels of the optimal conditions by oxygen mass transfer during amphotericin B biosynthesis.	Amphotericin B	136-150	CD59 molecule (CD59 blood group)	Homo sapiens	24-29
2730221-8	1989	min and n = less than 450 min-1) it was induced by insufficient supply of oxygen to the culture.	Oxygen	74-80	CD59 molecule (CD59 blood group)	Homo sapiens	26-31
2713212-4	1989	We have studied the effects of infused adenosine in doses of 0.005, 0.03 and 0.07 mg kg-1 min-1 on pulmonary blood flow and systemic vascular resistance in eight healthy volunteers, using a non-invasive, inert gas method and mass spectrometry.	Adenosine	39-48	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
2923770-2	1989	No desaturation occurred in six patients given oxygen 2 litre min-1 via a nasal catheter during similar procedures.	Oxygen	47-53	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
2713212-13	1989	We suggest that adenosine in doses of 0.03 mg kg-1 min-1 should be evaluated as a selective pulmonary vasodilator.	Adenosine	16-25	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
2499464-4	1989	The minute ventilation was increased by adenosine 5.3 to 15.9 mg (median values) from control 12.6 +/- 1.9 l min-1 to 42.5 +/- 4.7 l min-1 in a dose-dependent manner.	Adenosine	40-49	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
2706916-5	1989	Forty-five min after administration of nifedipine, FBF and heart rate had increased significantly (by 49% and seven beats x min-1, respectively, P less than 0.001), while no significant change was observed in systemic blood pressure.	Nifedipine	39-49	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
2499464-4	1989	The minute ventilation was increased by adenosine 5.3 to 15.9 mg (median values) from control 12.6 +/- 1.9 l min-1 to 42.5 +/- 4.7 l min-1 in a dose-dependent manner.	Adenosine	40-49	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
2715368-2	1989	The terminal elimination half-life was significantly prolonged in subjects with a creatinine clearance (ClCr) less than 30 mL/min/1.73 m2 (19.2 +/- 16.8 h) compared to 3.7 +/- 1.9 h in subjects with a ClCr greater than 80 mL/min/1.73 m2.	Creatinine	82-92	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
2715368-2	1989	The terminal elimination half-life was significantly prolonged in subjects with a creatinine clearance (ClCr) less than 30 mL/min/1.73 m2 (19.2 +/- 16.8 h) compared to 3.7 +/- 1.9 h in subjects with a ClCr greater than 80 mL/min/1.73 m2.	clcr	104-108	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
2918859-0	1989	Characterization of a broadly expressed human leucocyte surface antigen MEM-43 anchored in membrane through phosphatidylinositol.	Phosphatidylinositols	108-128	CD59 molecule (CD59 blood group)	Homo sapiens	72-78
2912969-4	1989	Application of a deuterium isotope effect of 2.8 led to rate constants in H2O for kC of 0.092 min-1 and kD of 0.73 min-1.	Deuterium	17-26	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
2912969-4	1989	Application of a deuterium isotope effect of 2.8 led to rate constants in H2O for kC of 0.092 min-1 and kD of 0.73 min-1.	Deuterium	17-26	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
2912969-4	1989	Application of a deuterium isotope effect of 2.8 led to rate constants in H2O for kC of 0.092 min-1 and kD of 0.73 min-1.	Water	74-77	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
2912969-4	1989	Application of a deuterium isotope effect of 2.8 led to rate constants in H2O for kC of 0.092 min-1 and kD of 0.73 min-1.	Water	74-77	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
2910843-11	1989	The optimum pH, Km value for PGH2, and the turnover number were 6.5, 100 microM, and 3.1 min-1, respectively.	Prostaglandin H2	29-33	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
2539852-5	1989	Deoxyguanosine, deoxyadenosine, and cytidine phosphorylating activities copurified with deoxycytidine kinase to final specific activities of 7.2, 13.5, and 4 mumol min-1 (mg of protein)-1, respectively.	Deoxyguanosine	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	164-187
2539852-5	1989	Deoxyguanosine, deoxyadenosine, and cytidine phosphorylating activities copurified with deoxycytidine kinase to final specific activities of 7.2, 13.5, and 4 mumol min-1 (mg of protein)-1, respectively.	2'-deoxyadenosine	16-30	CD59 molecule (CD59 blood group)	Homo sapiens	164-187
2539852-5	1989	Deoxyguanosine, deoxyadenosine, and cytidine phosphorylating activities copurified with deoxycytidine kinase to final specific activities of 7.2, 13.5, and 4 mumol min-1 (mg of protein)-1, respectively.	Cytidine	36-44	CD59 molecule (CD59 blood group)	Homo sapiens	164-187
2624704-2	1989	The rate of hydrolysis was subject to specific acid catalysis, the specific hydrogen ion catalytic rate constant being 3.6 X 10(-3) M-1 min-1 at 37 degrees C and mu = 0.5.	Hydrogen	76-84	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
2643255-7	1989	Theophylline, at a dose blocking the coronary flow response to dipyridamole (an adenosine-dependent mechanism), induced a moderate increase in myocardial oxygen extraction (by 11%, P less than 0.05), but failed to affect either the basal coronary flow (105 +/- 16 ml min-1) or the increase during exercise (88 +/- 25 ml min-1).	Theophylline	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	267-272
2643255-7	1989	Theophylline, at a dose blocking the coronary flow response to dipyridamole (an adenosine-dependent mechanism), induced a moderate increase in myocardial oxygen extraction (by 11%, P less than 0.05), but failed to affect either the basal coronary flow (105 +/- 16 ml min-1) or the increase during exercise (88 +/- 25 ml min-1).	Theophylline	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	320-325
2643255-7	1989	Theophylline, at a dose blocking the coronary flow response to dipyridamole (an adenosine-dependent mechanism), induced a moderate increase in myocardial oxygen extraction (by 11%, P less than 0.05), but failed to affect either the basal coronary flow (105 +/- 16 ml min-1) or the increase during exercise (88 +/- 25 ml min-1).	Adenosine	80-89	CD59 molecule (CD59 blood group)	Homo sapiens	267-272
2643255-7	1989	Theophylline, at a dose blocking the coronary flow response to dipyridamole (an adenosine-dependent mechanism), induced a moderate increase in myocardial oxygen extraction (by 11%, P less than 0.05), but failed to affect either the basal coronary flow (105 +/- 16 ml min-1) or the increase during exercise (88 +/- 25 ml min-1).	Adenosine	80-89	CD59 molecule (CD59 blood group)	Homo sapiens	320-325
2711919-4	1989	On naproxen, ERPF and renal blood flow decreased by 10% and 9%, respectively (-32 ml/min/1.73 m2; p = 0.05 and -49 ml/min/1.73 m2; p less than 0.01).	Naproxen	3-11	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
2711919-4	1989	On naproxen, ERPF and renal blood flow decreased by 10% and 9%, respectively (-32 ml/min/1.73 m2; p = 0.05 and -49 ml/min/1.73 m2; p less than 0.01).	Naproxen	3-11	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
2757077-4	1989	The GFR (125I-iothalamate clearance) changed from 42.6 to 45.6 ml/min/1.73 m2 in period A, from 51.9 to 40.7 in period B and from 40.5 to 44.6 in period C. The results show changes in renal function when dietary protein and phosphate intakes exceeding 0.6 g/kg and 600 mg/day, respectively, are administered to patients with GFRs ranging from 24 to 66 ml/min.	125i-iothalamate	9-25	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
2912154-8	1989	Conversely, zinc (0.9 mM) also enhanced the absorption of glucose, which was increased from 293 +/- 43 to 447 +/- 27 microM.min-1.40 cm-1 (P less than 0.05).	Glucose	58-65	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
2712404-4	1989	The administration of 10.6 +/- 0.5 micrograms.kg-1.min-1 dobutamine (starting dose: 6 micrograms.kg-1.min-1) was started when the cardiac index (CI) was less than 3.3 l.min-1.m-2 after vascular filling with plasma expanders.	Dobutamine	57-67	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
2712404-4	1989	The administration of 10.6 +/- 0.5 micrograms.kg-1.min-1 dobutamine (starting dose: 6 micrograms.kg-1.min-1) was started when the cardiac index (CI) was less than 3.3 l.min-1.m-2 after vascular filling with plasma expanders.	Dobutamine	57-67	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
2712404-4	1989	The administration of 10.6 +/- 0.5 micrograms.kg-1.min-1 dobutamine (starting dose: 6 micrograms.kg-1.min-1) was started when the cardiac index (CI) was less than 3.3 l.min-1.m-2 after vascular filling with plasma expanders.	Dobutamine	57-67	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
2712404-6	1989	This drug was given at a constant rate with a starting dose of 0.5 micrograms.kg-1.min-1, increased every 10 min by 0.3 to 0.6 micrograms.kg-1.min-1 according to the effects on Pasys and hourly urine output.	pasys	177-182	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
2604320-3	1989	The aerosol concentrations were achieved by passing air through the nebulizer at 1.5-4.5 l. min-1 to generate dynamically 0.01-0.25 ppm of diisocyanate in an experimental chamber of 8.55 m3.	4,4'-diphenylmethane diisocyanate	139-151	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
2912385-3	1989	Purified rubisco activase hydrolyzed ATP with a specific activity of 1.5 mumol min-1 mg-1 protein, releasing approximately stoichiometric amounts of ADP and Pi.	Adenosine Triphosphate	37-40	CD59 molecule (CD59 blood group)	Homo sapiens	79-89
2912385-3	1989	Purified rubisco activase hydrolyzed ATP with a specific activity of 1.5 mumol min-1 mg-1 protein, releasing approximately stoichiometric amounts of ADP and Pi.	Adenosine Diphosphate	149-152	CD59 molecule (CD59 blood group)	Homo sapiens	79-89
2923963-2	1989	The control mean theophylline half-life and clearance were 7.32 h and 0.86 ml min-1 kg-1, respectively.	Theophylline	17-29	CD59 molecule (CD59 blood group)	Homo sapiens	78-88
2495813-13	1989	Alinidine administered 2 h before a glyceryl trinitrate challenge reduced (P less than 0.05) the glyceryl trinitrate induced increase in standing heart rate at all time intervals (1 to 6 min); the maximum reduction occurred at 3 min (105.0 +/- 4.3 (glyceryl trinitrate) vs 86.8 +/- 6.7 beats min-1 (combination].	alinidine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	292-297
2495813-13	1989	Alinidine administered 2 h before a glyceryl trinitrate challenge reduced (P less than 0.05) the glyceryl trinitrate induced increase in standing heart rate at all time intervals (1 to 6 min); the maximum reduction occurred at 3 min (105.0 +/- 4.3 (glyceryl trinitrate) vs 86.8 +/- 6.7 beats min-1 (combination].	Nitroglycerin	97-116	CD59 molecule (CD59 blood group)	Homo sapiens	292-297
2495813-13	1989	Alinidine administered 2 h before a glyceryl trinitrate challenge reduced (P less than 0.05) the glyceryl trinitrate induced increase in standing heart rate at all time intervals (1 to 6 min); the maximum reduction occurred at 3 min (105.0 +/- 4.3 (glyceryl trinitrate) vs 86.8 +/- 6.7 beats min-1 (combination].	Nitroglycerin	97-116	CD59 molecule (CD59 blood group)	Homo sapiens	292-297
2527539-19	1989	When creatinine clearance was below 15 ml min-1 cilazaprilat concentrations were increased, half-lives were prolonged and ACE inhibition remained above 90% for at least 24 h. A reduced dosage is indicated for these patients.	cilazaprilat	48-60	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
2548552-15	1989	mean, was 1.7 +/- 0.3 micrograms min-1 during control-trials vs 7.3 +/- 1.3 micrograms min-1 after ACE inhibition with cilazapril (P less than 0.001).	Cilazapril	119-129	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
2572250-5	1989	Resting heart rate fell from 78 to 74 beats min-1 (P less than 0.05) and cardiac index rose from 2.5 to 2.8 l min-1 m-2 (P less than 0.001) after xamoterol.	Xamoterol	146-155	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
2538260-2	1989	Significant differences in the survival patterns were noted when analysed on the basis of the preoperative indocyanine green maximal removal rate (greater than 0.4 mg kg-1 min-1 versus less than 0.4 mg kg-1 min-1), tumor size (greater than 5 cm versus less than 5 cm, etc.)	Indocyanine Green	107-124	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
2713960-3	1989	For total prednisolone, the mean elimination half-life was relatively short (1.37 h) and the total clearance, relatively high (15.1 ml min-1 kg-1).	Prednisolone	10-22	CD59 molecule (CD59 blood group)	Homo sapiens	135-145
2783663-3	1989	Extubation from a continuous positive airway pressure (CPAP) of 5 cm H2O was associated with a statistically significant rise in cardiac index from 3.44 +/- 0.23 L.min-1.m-2 to 3.73 +/- 0.15 L.min-1.m-2 related to an increase in stroke index, without significant changes in heart rate, mean arterial and pulmonary capillary wedge pressure.	Water	69-72	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
2783663-3	1989	Extubation from a continuous positive airway pressure (CPAP) of 5 cm H2O was associated with a statistically significant rise in cardiac index from 3.44 +/- 0.23 L.min-1.m-2 to 3.73 +/- 0.15 L.min-1.m-2 related to an increase in stroke index, without significant changes in heart rate, mean arterial and pulmonary capillary wedge pressure.	Water	69-72	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
2568929-1	1989	The pharmacokinetics of the H2-receptor antagonist famotidine, after oral administration of a 20 mg tablet, has been studied in 10 elderly patients with normal renal function (CLCR greater than or equal to 59 ml.min-1, Mean = 80 ml.min-1), 5 elderly patients with renal insufficiency (CLCR less than or equal to 38 ml.min-1, Mean = 15 ml.min-1), and 6 healthy young volunteers.	Famotidine	51-61	CD59 molecule (CD59 blood group)	Homo sapiens	212-217
2568929-5	1989	The mean renal clearance of famotidine in the young volunteers (270 ml.min-1) was substantially greater than the creatinine clearance, 128 ml.min-1, which suggests the possibility of tubular secretion of famotidine.	Famotidine	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
2570700-2	1989	Following placebo, the dose of isoproterenol which increased the heart rate by 25 beats.min-1 (CD25) was 0.84 (0.1-2.72) micrograms (median and range).	Isoproterenol	31-44	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
2574673-6	1989	The mean plasma clearance of remoxipride was 141 and 89.9 ml.min-1 in the acidic and alkaline conditions, respectively, and the corresponding mean renal clearances were 58.5 ml.min-1 and 11.7 ml.min-1.	Remoxipride	29-40	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
2702965-3	1989	Mean creatinine clearance of the healthy subjects was 129.7 +/- 3.3 ml min-1 (mean +/- SEM), that of the patients was 25.6 +/- 20.4 ml min-1.	Creatinine	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
2702965-6	1989	Total body clearance of digitoxin (Cltot) was 0.0728 +/- 0.0120 ml min-1 kg-1 in the patients and 0.0615 +/- 0.0027 ml min-1 kg-1 in normals (n.s.].	Digitoxin	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	67-77
2702965-6	1989	Total body clearance of digitoxin (Cltot) was 0.0728 +/- 0.0120 ml min-1 kg-1 in the patients and 0.0615 +/- 0.0027 ml min-1 kg-1 in normals (n.s.].	Digitoxin	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
2702965-6	1989	Total body clearance of digitoxin (Cltot) was 0.0728 +/- 0.0120 ml min-1 kg-1 in the patients and 0.0615 +/- 0.0027 ml min-1 kg-1 in normals (n.s.].	cltot	35-40	CD59 molecule (CD59 blood group)	Homo sapiens	67-77
2702965-6	1989	Total body clearance of digitoxin (Cltot) was 0.0728 +/- 0.0120 ml min-1 kg-1 in the patients and 0.0615 +/- 0.0027 ml min-1 kg-1 in normals (n.s.].	cltot	35-40	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
2714265-5	1989	Renal clearance of articaine varies between 12 and 28 ml min-1, while that of articainic acid is between 84 and 160 ml min-1.	Carticaine	19-28	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
2714265-5	1989	Renal clearance of articaine varies between 12 and 28 ml min-1, while that of articainic acid is between 84 and 160 ml min-1.	2-carboxyarticaine	78-93	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
2737228-6	1989	Endogenous creatinine clearance normalized to 70 kg in burned children was 190 ml.min-1.	Creatinine	11-21	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
2737234-4	1989	Total oxazepam clearance was 1.04 ml.min-1.kg-1 and it decreased 0.88-fold after the diet.	Oxazepam	6-14	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
2753062-2	1989	The AUC (0-24) and the elimination half-life of nitrendipine were significantly increased; the AUC (0-24) in patients with renal failure (median creatinine clearance 27.1 ml x min-1) was 196 ng x ml-1 x h compared to 97.8 ng x ml-1 x h in control subjects (median creatinine clearance 94.4 ml x min-1).	Nitrendipine	48-60	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
2753062-2	1989	The AUC (0-24) and the elimination half-life of nitrendipine were significantly increased; the AUC (0-24) in patients with renal failure (median creatinine clearance 27.1 ml x min-1) was 196 ng x ml-1 x h compared to 97.8 ng x ml-1 x h in control subjects (median creatinine clearance 94.4 ml x min-1).	Nitrendipine	48-60	CD59 molecule (CD59 blood group)	Homo sapiens	295-300
2753067-9	1989	The mean terminal half-life of terodiline was 131 h and the clearance after oral administration (clearance/systemic availability) was 39 ml.min-1.	terodiline	31-41	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
2792166-6	1989	In these 6 volunteers, intake of diltiazem (240 mg daily), concurrently with rifampicin for a week, significantly elevated theophylline half-life to 6.2 h as well as reduced its clearance to 1.03 ml.min-1.kg-1.	Diltiazem	33-42	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
2792166-6	1989	In these 6 volunteers, intake of diltiazem (240 mg daily), concurrently with rifampicin for a week, significantly elevated theophylline half-life to 6.2 h as well as reduced its clearance to 1.03 ml.min-1.kg-1.	Rifampin	77-87	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
2924759-5	1989	During walking on the treadmill, the means for oxygen consumption were 0.79 +/- 0.05, 0.81 +/- 0.06 and 0.83 +/- 0.04 l min-1 (NS) and in snow 2.24 +/- 0.18, 2.34 +/- 0.17 and 2.34 +/- 0.19 l min-1 (p less than 0.01) with the WJB, RB and RSB, respectively.	Oxygen	47-53	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
2555276-1	1989	In a series of hydroxyethylaminoalkylaminoanthraquinones (AQ"s) based on mitozantrone, 1-AQ (340%) and 1,8-AQ (137%) stimulated basal rate NADPH oxidation (72 + 18 pmol min-1 mg S9 protein-1) whilst 1,4-AQ, 1,5-AQ and mitozantrone had no effect.	hydroxyethylaminoalkylaminoanthraquinones	15-56	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2555276-1	1989	In a series of hydroxyethylaminoalkylaminoanthraquinones (AQ"s) based on mitozantrone, 1-AQ (340%) and 1,8-AQ (137%) stimulated basal rate NADPH oxidation (72 + 18 pmol min-1 mg S9 protein-1) whilst 1,4-AQ, 1,5-AQ and mitozantrone had no effect.	aq"s	58-62	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2555276-1	1989	In a series of hydroxyethylaminoalkylaminoanthraquinones (AQ"s) based on mitozantrone, 1-AQ (340%) and 1,8-AQ (137%) stimulated basal rate NADPH oxidation (72 + 18 pmol min-1 mg S9 protein-1) whilst 1,4-AQ, 1,5-AQ and mitozantrone had no effect.	1-aq	87-91	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2555276-1	1989	In a series of hydroxyethylaminoalkylaminoanthraquinones (AQ"s) based on mitozantrone, 1-AQ (340%) and 1,8-AQ (137%) stimulated basal rate NADPH oxidation (72 + 18 pmol min-1 mg S9 protein-1) whilst 1,4-AQ, 1,5-AQ and mitozantrone had no effect.	1,8-aq	103-109	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2555276-1	1989	In a series of hydroxyethylaminoalkylaminoanthraquinones (AQ"s) based on mitozantrone, 1-AQ (340%) and 1,8-AQ (137%) stimulated basal rate NADPH oxidation (72 + 18 pmol min-1 mg S9 protein-1) whilst 1,4-AQ, 1,5-AQ and mitozantrone had no effect.	NADP	139-144	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
2555276-3	1989	cyt c reduction min-1 mg protein-1) by these compounds in MCF-7 S9 fraction: 1-AQ (9.5) and 1,8-AQ (7.9), whilst 1,5-AQ, 1,4-AQ and mitozantrone showed no significant effect.	1-aq	77-81	CD59 molecule (CD59 blood group)	Homo sapiens	16-21
2555276-3	1989	cyt c reduction min-1 mg protein-1) by these compounds in MCF-7 S9 fraction: 1-AQ (9.5) and 1,8-AQ (7.9), whilst 1,5-AQ, 1,4-AQ and mitozantrone showed no significant effect.	1,8-aq	92-98	CD59 molecule (CD59 blood group)	Homo sapiens	16-21
2555276-3	1989	cyt c reduction min-1 mg protein-1) by these compounds in MCF-7 S9 fraction: 1-AQ (9.5) and 1,8-AQ (7.9), whilst 1,5-AQ, 1,4-AQ and mitozantrone showed no significant effect.	1,5-aq	113-119	CD59 molecule (CD59 blood group)	Homo sapiens	16-21
2555276-3	1989	cyt c reduction min-1 mg protein-1) by these compounds in MCF-7 S9 fraction: 1-AQ (9.5) and 1,8-AQ (7.9), whilst 1,5-AQ, 1,4-AQ and mitozantrone showed no significant effect.	1,4-aq	121-127	CD59 molecule (CD59 blood group)	Homo sapiens	16-21
2555276-3	1989	cyt c reduction min-1 mg protein-1) by these compounds in MCF-7 S9 fraction: 1-AQ (9.5) and 1,8-AQ (7.9), whilst 1,5-AQ, 1,4-AQ and mitozantrone showed no significant effect.	Mitoxantrone	132-144	CD59 molecule (CD59 blood group)	Homo sapiens	16-21
2544635-5	1989	DP and DB were administered alternatively at a rate of 5 micrograms.k-1 min-1.	Dopamine	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
2544635-7	1989	Both drugs similarly increased cardiac output: +2.61.min-1 +/- 1.4 for DP and 2.21.min-1 +/- 1.5 for DB.	Dobutamine	101-103	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
2745868-5	1989	Initially the mean infusion rate of etomidate required to achieve adequate suppression of cortical activity was 25 micrograms kg-1 min-1, but several patients exhibited tachyphylaxis.	Etomidate	36-45	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
2621761-2	1989	with terminal heart rate and blood lactate of 152 +/- 6 beats min-1 and 6.9 +/- 0.89 mM, respectively.	Lactic Acid	35-42	CD59 molecule (CD59 blood group)	Homo sapiens	62-75
2544817-4	1989	On the control day, creatinine clearance increased from 114.3 +/- 4.7 before the meal to 137.1 +/- 4.7 ml/min/1.73 m2 after the meal (p less than 0.001).	Creatinine	20-30	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
2544817-5	1989	On the enalapril intake day, creatinine clearance increased from 113.7 +/- 5.6 before the meal to 128.3 +/- 5.8 ml/min/1.73 m2 after the meal (p less than 0.01).	Enalapril	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
2919032-9	1989	This was confirmed by the exaggerated response to frusemide reflected by urinary flow measurements in patients with a creatinine clearance of 10 ml min-1 or less.	Furosemide	50-59	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
2919032-9	1989	This was confirmed by the exaggerated response to frusemide reflected by urinary flow measurements in patients with a creatinine clearance of 10 ml min-1 or less.	Creatinine	118-128	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
2633329-9	1989	One year after surgery the Harris hip score had increased from 35 to 85 points and maximal walking speed from 62 to 80 m min-1 Oxygen cost had decreased from 0.267 to 0.221 ml kg-1m-1.	Oxygen	127-133	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
2792172-5	1989	A decrease in plasma albumin concentration from 33 g.l-1 after albumin infusion to 23 g.l-1 after infusion of dextran caused a substantial increase in the renal clearance (from 84 to 123 ml.min-1), non-renal clearance (from 72 to 138 ml.min-1), and apparent volume of distribution (from 13 to 23 l) of frusemide, probably as a consequence of an increase in the unbound fraction.	Dextrans	110-117	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
2792172-5	1989	A decrease in plasma albumin concentration from 33 g.l-1 after albumin infusion to 23 g.l-1 after infusion of dextran caused a substantial increase in the renal clearance (from 84 to 123 ml.min-1), non-renal clearance (from 72 to 138 ml.min-1), and apparent volume of distribution (from 13 to 23 l) of frusemide, probably as a consequence of an increase in the unbound fraction.	Dextrans	110-117	CD59 molecule (CD59 blood group)	Homo sapiens	237-242
3198633-3	1988	At 200 mV and 1 mM spermine, the observed rate of spermine uptake was about 7 nmol x mg-1 x min-1, and the rate constant was about 8 times greater than that of tetraethylammonium cation.	Spermine	19-27	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
2799693-1	1989	During osteomalacia in patients with terminal renal failure, the coefficient of diphosphonate elimination from the blood bed (K1) was less than 0.1 min-1, which was determined by the rise of the concentration of uremic toxins, inhibiting interaction of the radiopharmaceutical with the bone, in the patients" tissues.	Diphosphonates	80-93	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
3198633-3	1988	At 200 mV and 1 mM spermine, the observed rate of spermine uptake was about 7 nmol x mg-1 x min-1, and the rate constant was about 8 times greater than that of tetraethylammonium cation.	Spermine	50-58	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
3218606-2	1988	Progressive, dose-related increases in plasma histamine were noted, reaching a maximum value of 3.1 +/- 0.14 ng ml-1 corresponding to a maximum infusion rate of 180 ng kg-1 min-1 (means +/- SEM).	Histamine	46-55	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
3202903-2	1988	The choline phospholipids (11 mumol/g) maintained a constant efflux of choline of about 1.5 nmol g-1 min-1 into the perfusate.	Choline	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
3202903-2	1988	The choline phospholipids (11 mumol/g) maintained a constant efflux of choline of about 1.5 nmol g-1 min-1 into the perfusate.	Phospholipids	12-25	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
3202903-2	1988	The choline phospholipids (11 mumol/g) maintained a constant efflux of choline of about 1.5 nmol g-1 min-1 into the perfusate.	Choline	71-78	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
3264120-6	1988	Rapid and slow propofol distribution half-times were observed, followed by an elimination phase with a half-time of 4-5 h. Propofol total body clearance was reduced (1.99 +/- 0.68 l.min-1) in the patients with cirrhosis but did not differ significantly from that in the control patients (2.30 +/- 0.61 l.min-1).	Propofol	123-131	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
3264120-6	1988	Rapid and slow propofol distribution half-times were observed, followed by an elimination phase with a half-time of 4-5 h. Propofol total body clearance was reduced (1.99 +/- 0.68 l.min-1) in the patients with cirrhosis but did not differ significantly from that in the control patients (2.30 +/- 0.61 l.min-1).	Propofol	123-131	CD59 molecule (CD59 blood group)	Homo sapiens	304-309
2465016-4	1988	Ifosfamide, however, led to substantial additional growth delay, an effect which was lost when irradiation was administered at a higher dose rate of 70 cGy min-1.	Ifosfamide	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
2465016-5	1988	As dose-rates of around 5 cGy min-1 allow greater repair of radiation damage than at the higher dose-rate without significant cell cycling or repopulation, it is possible that ifosfamide may act as an inhibitor of repair processes in this model.	Ifosfamide	176-186	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
2849968-5	1988	Pipecuronium had a larger steady-state volume of distribution (Vss) (309 (SD 103) ml kg-1) and greater plasma clearance (Cl) (2.4 (0.6) ml kg-1 min-1) than pancuronium (199 (54) ml kg-1 and 1.5 (0.4) ml kg-1 min-1, respectively).	Pipecuronium	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
2849968-5	1988	Pipecuronium had a larger steady-state volume of distribution (Vss) (309 (SD 103) ml kg-1) and greater plasma clearance (Cl) (2.4 (0.6) ml kg-1 min-1) than pancuronium (199 (54) ml kg-1 and 1.5 (0.4) ml kg-1 min-1, respectively).	Pipecuronium	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
3242582-8	1988	Creatinine clearances for the 21 patients ranged from 6-162 ml min-1.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
2976647-5	1988	Twelve diet-treated diabetic patients and 11 normal subjects were given a continuous low-dose glucose infusion for 60 min at a rate of 5 mg kg-1 ideal body weight min-1, after which the infusion was turned off and the plasma glucose level allowed to fall.	Glucose	94-101	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
3243040-7	1988	In contrast, creatinine clearances (mean +/- SEM, ml/min/1.73 m2) in men significantly decreased over both 1 year (110 +/- 4 to 95 +/- 5, n = 21, p = 0.0126) and 3 years (107 +/- 4 to 80 +/- 11, n = 8, p = 0.0385) of evaluation.	Creatinine	13-23	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
3246249-5	1988	Heart rate decreased significantly with amiodarone (from 76.9 to 69.5 beats min-1) as did premature ventricular complexes (from 4686 to 329 day-1), ventricular couplets (from 154.3 to 5.0 day-1), ventricular tachycardia runs (from 91.7 to 0).	Amiodarone	40-50	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
3215871-6	1988	Mean values for rectal temperature (rate of increase) were 0.022 +/- 0.009 (SD) degrees C.min-1 for liquid O2 and 0.036 +/- 0.015 degrees C.min-1 for compressed O2 (P less than 0.005, 2-sided paired t test).	Oxygen	107-109	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
3215871-6	1988	Mean values for rectal temperature (rate of increase) were 0.022 +/- 0.009 (SD) degrees C.min-1 for liquid O2 and 0.036 +/- 0.015 degrees C.min-1 for compressed O2 (P less than 0.005, 2-sided paired t test).	Oxygen	161-163	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
3215871-7	1988	Mean values for heart rate (rate of increase) were 2.64 +/- 0.74 (SD) min-2 for liquid O2 and 3.27 +/- 0.89 min-2 for compressed O2 (P less than 0.02, 2-sided paired t test).	Oxygen	129-131	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
3246544-6	1988	Fetal oxygen uptake increased from 5.7 +/- 0.3 to 6.5 +/- 0.4 ml.min-1 kg-1 (P less than 0.005) during contractures.	Oxygen	6-12	CD59 molecule (CD59 blood group)	Homo sapiens	65-75
3218606-3	1988	Increases in plasma histamine were accompanied by a significant dose-related fall in mean diastolic blood pressure (baseline 74.0 +/- 4.4 mm Hg falling to 60.0 +/- 3.3 mm Hg at maximum infusion rate, p less than 0.001) and an increase in pulse rate (baseline 76.3 +/- 2.8 beats min-1 rising to 89.24 beats min-1 at maximum infusion rate, p less than 0.05).	Histamine	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	278-283
3218606-3	1988	Increases in plasma histamine were accompanied by a significant dose-related fall in mean diastolic blood pressure (baseline 74.0 +/- 4.4 mm Hg falling to 60.0 +/- 3.3 mm Hg at maximum infusion rate, p less than 0.001) and an increase in pulse rate (baseline 76.3 +/- 2.8 beats min-1 rising to 89.24 beats min-1 at maximum infusion rate, p less than 0.05).	Histamine	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	306-311
3218606-4	1988	All subjects exhibited facial flushing, the threshold plasma histamine level for this effect being 1.3 +/- 0.15 ng ml-1 corresponding to an infusion rate of 60 ng kg-1 min-1.	Histamine	61-70	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
3238640-4	1988	Portable oxygen (41 min-1) carried by the patient increased the mean endurance walking time by 59% and the six minute walking distance by 17%.	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	20-25
3238640-5	1988	The endurance time for cycling at a constant work load was increased by 51% with oxygen at a flow rate of 21 min-1, by 88% at 41 min-1, and by 80% at 61 min-1.	Oxygen	81-87	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
3140674-4	1988	Kinetic parameters for ATP-dependent Ca2+ uptake revealed a Michaelis constant (Km) of 0.02 +/- 0.01 microM and a maximum rate of uptake (Vmax) of 1.00 +/- 0.03 nmol.mg protein-1.min-1.Ca2+ uptake in the absence of Mg2+ was inhibited by 75%.	Adenosine Triphosphate	23-26	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
3207561-5	1988	mean) renal clearance of sulphadimidine was increased from 0.03 +/- 0.01 to 0.07 +/- 0.02 ml min-1 kg-1 (P = 0.01) following the administration of intra-articular steroid.	Sulfamethazine	25-39	CD59 molecule (CD59 blood group)	Homo sapiens	93-103
3207561-5	1988	mean) renal clearance of sulphadimidine was increased from 0.03 +/- 0.01 to 0.07 +/- 0.02 ml min-1 kg-1 (P = 0.01) following the administration of intra-articular steroid.	Steroids	163-170	CD59 molecule (CD59 blood group)	Homo sapiens	93-103
3254763-4	1988	Five doses of noradrenaline, 0-54 ng min-1 kg-1, were infused intravenously in random order and single-blind for 15 min per dose.	Norepinephrine	14-27	CD59 molecule (CD59 blood group)	Homo sapiens	37-47
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
3054431-4	1988	During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1.	Glucose	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
3054431-5	1988	During the euglycemic clamp glucose tissue uptake was 4.4 +/- 0.3 mg x kg-1 x min-1, glucose oxidation rose to 1.8 mg x kg-1 x min-1 (.001 less than P less than .01), FFA concentration dropped to 202 +/- 23 mumol x L-1 (P less than .001), and lipid oxidation to 1.2 +/- 0.2 mumol x kg-1 x min-1 (.001 less than P less than .01).	Glucose	28-35	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
3054431-7	1988	It is concluded that in septic cancer-bearing patients glucose oxidation is inhibited during infusion of 3.9 mg glucose x kg-1 x min-1, even when expressed as percentage of glucose tissue uptake.	Glucose	55-62	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
3054431-7	1988	It is concluded that in septic cancer-bearing patients glucose oxidation is inhibited during infusion of 3.9 mg glucose x kg-1 x min-1, even when expressed as percentage of glucose tissue uptake.	Glucose	112-119	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
3054431-7	1988	It is concluded that in septic cancer-bearing patients glucose oxidation is inhibited during infusion of 3.9 mg glucose x kg-1 x min-1, even when expressed as percentage of glucose tissue uptake.	Glucose	112-119	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
2851193-2	1988	When rt-PA was treated with sodium periodate to oxidize carbohydrate residues, the rate of clearance was decreased from 9.6 +/- 1.9 ml min-1 kg-1 to 3.5 +/- 0.6 ml min-1 kg-1 (mean +/- SD, n = 5).	rt-pa	5-10	CD59 molecule (CD59 blood group)	Homo sapiens	135-145
2851193-2	1988	When rt-PA was treated with sodium periodate to oxidize carbohydrate residues, the rate of clearance was decreased from 9.6 +/- 1.9 ml min-1 kg-1 to 3.5 +/- 0.6 ml min-1 kg-1 (mean +/- SD, n = 5).	rt-pa	5-10	CD59 molecule (CD59 blood group)	Homo sapiens	164-174
2851193-2	1988	When rt-PA was treated with sodium periodate to oxidize carbohydrate residues, the rate of clearance was decreased from 9.6 +/- 1.9 ml min-1 kg-1 to 3.5 +/- 0.6 ml min-1 kg-1 (mean +/- SD, n = 5).	metaperiodate	28-44	CD59 molecule (CD59 blood group)	Homo sapiens	135-145
2851193-2	1988	When rt-PA was treated with sodium periodate to oxidize carbohydrate residues, the rate of clearance was decreased from 9.6 +/- 1.9 ml min-1 kg-1 to 3.5 +/- 0.6 ml min-1 kg-1 (mean +/- SD, n = 5).	metaperiodate	28-44	CD59 molecule (CD59 blood group)	Homo sapiens	164-174
2851193-2	1988	When rt-PA was treated with sodium periodate to oxidize carbohydrate residues, the rate of clearance was decreased from 9.6 +/- 1.9 ml min-1 kg-1 to 3.5 +/- 0.6 ml min-1 kg-1 (mean +/- SD, n = 5).	Carbohydrates	56-68	CD59 molecule (CD59 blood group)	Homo sapiens	135-145
2851193-2	1988	When rt-PA was treated with sodium periodate to oxidize carbohydrate residues, the rate of clearance was decreased from 9.6 +/- 1.9 ml min-1 kg-1 to 3.5 +/- 0.6 ml min-1 kg-1 (mean +/- SD, n = 5).	Carbohydrates	56-68	CD59 molecule (CD59 blood group)	Homo sapiens	164-174
2851193-3	1988	A similar change in the clearance of rt-PA was introduced by the use of endo-beta-N-acetyl-glucosaminidase H (Endo-H), which selectively removes high mannose asparagine-linked oligosaccharides; the clearance of Endo-H-treated rt-PA was 5.0 +/- 0.5 ml min-1 kg-1.	rt-pa	37-42	CD59 molecule (CD59 blood group)	Homo sapiens	251-261
3227943-1	1988	Seven men performed one-legged isometric knee extension at 5% MVC for 1 h. Total body oxygen uptake amounted to 451 (420-471) ml min-1 and oxygen uptake over the contracting leg to 200 (172-216) ml min-1, with no changes occurring during the 1 h contraction.	Oxygen	86-92	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
3048161-9	1988	Oral cysteamine lowered leukocyte cystine over 80%, and in patients before transplant, improved growth and preserved renal function (mean creatinine clearance [+/- SE], 0.64 +/- 0.04 mL/s.1.73 m2 [38.5 +/- 2.5 mL/min.1.73 m2] in the cysteamine group compared with 0.50 +/- 0.03 mL/s.1.73 m2 [29.7 +/- 2.0 mL/min.1.73 m2] in controls; 95% CI for the difference, 1.8 to 15.8).	Cysteamine	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	213-218
3048161-9	1988	Oral cysteamine lowered leukocyte cystine over 80%, and in patients before transplant, improved growth and preserved renal function (mean creatinine clearance [+/- SE], 0.64 +/- 0.04 mL/s.1.73 m2 [38.5 +/- 2.5 mL/min.1.73 m2] in the cysteamine group compared with 0.50 +/- 0.03 mL/s.1.73 m2 [29.7 +/- 2.0 mL/min.1.73 m2] in controls; 95% CI for the difference, 1.8 to 15.8).	Cysteamine	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	308-313
3190187-5	1988	Ofloxacin kinetics after the single dose were best described by a two-phase curve with a total body clearance of 241.6 +/- 43.3 ml min-1, a volume of distribution of 112 +/- 23.1 liters, and an elimination half-life of 5.4 +/- 0.8 h. The extrapolated area under the curve (AUC0-infinity) was 14 +/- 2.3 mg.h liter-1.	Ofloxacin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
3190988-7	1988	The mean values of dialysis clearance, total serum clearance during dialysis, fractional drug removal during haemodialysis and half-life during dialysis for amoxycillin were 77.1 ml min-1, 91.5 ml min-1, 0.64 and 2.30 h, respectively.	Amoxicillin	157-168	CD59 molecule (CD59 blood group)	Homo sapiens	197-202
3190988-5	1988	The mean values of total serum clearance, mean residence time, volume of distribution at steady state, and terminal half-life for amoxycillin on the non-dialysis day were 14.4 ml min-1, 19.2 h, 14.9 l and 13.6 h, respectively.	Amoxicillin	130-141	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
3190988-7	1988	The mean values of dialysis clearance, total serum clearance during dialysis, fractional drug removal during haemodialysis and half-life during dialysis for amoxycillin were 77.1 ml min-1, 91.5 ml min-1, 0.64 and 2.30 h, respectively.	Amoxicillin	157-168	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
3190988-9	1988	The mean values of total serum clearance, mean residence time, volume of distribution at steady state, and terminal half-life for clavulanic acid on the non-dialysis day were 43.6 ml min-1, 4.4 h, 11.0 l and 3.05 h, respectively.	Clavulanic Acid	130-145	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
3190988-11	1988	The mean values of dialysis clearance, total serum clearance during dialysis, fractional drug removal during haemodialysis and half-life during dialysis for clavulanic acid were 92.8 ml min-1, 136 ml min-1, 0.65 and 1.19 h, respectively.	Clavulanic Acid	157-172	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
3190988-11	1988	The mean values of dialysis clearance, total serum clearance during dialysis, fractional drug removal during haemodialysis and half-life during dialysis for clavulanic acid were 92.8 ml min-1, 136 ml min-1, 0.65 and 1.19 h, respectively.	Clavulanic Acid	157-172	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
3190991-6	1988	The area under the serum concentration vs time curve (AUC) of 3-hydroxyquinidine was greater at steady state than after the single dose (2.0 +/- 0.7 vs 3.0 +/- 0.6 mg l-1 h; P less than 0.05) and its renal clearance was less (3.0 +/- 1.1 vs 1.54 +/- 0.38 ml min-1 kg-1; P less than 0.05).	3-hydroxyquinidine	62-80	CD59 molecule (CD59 blood group)	Homo sapiens	258-268
3242682-4	1988	A range of glucose production of 3.5-1.8 mg kg-1 min-1 was found when glucose infusion rates increased from 0.13 to 6 mg kg-1 min-1.	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
3242682-4	1988	A range of glucose production of 3.5-1.8 mg kg-1 min-1 was found when glucose infusion rates increased from 0.13 to 6 mg kg-1 min-1.	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
3242682-4	1988	A range of glucose production of 3.5-1.8 mg kg-1 min-1 was found when glucose infusion rates increased from 0.13 to 6 mg kg-1 min-1.	Glucose	70-77	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
3242682-4	1988	A range of glucose production of 3.5-1.8 mg kg-1 min-1 was found when glucose infusion rates increased from 0.13 to 6 mg kg-1 min-1.	Glucose	70-77	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
3190994-11	1988	After the single doses, pholcodine was absorbed rapidly (tmax = 1.6 +/- 1.2 h) and eliminated slowly with a mean half-life of 50.1 +/- 4.1 h. The renal clearance of pholcodine was 137 +/- 34 ml min-1 and was inversely correlated with urine pH (r = 0.60) but not with urine flow rate.	pholcodine	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	194-199
3191000-2	1988	During 6 months of follow-up, blood pressure did not change, whereas minoxidil increased heart rate by 3-5 beats min-1.	Minoxidil	69-78	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
3191000-3	1988	Compared with placebo, topical minoxidil caused significant increases in LV end-diastolic volume, in cardiac output (by 0.751 min-1) and in LV mass (by 5 g m-2).	Minoxidil	31-40	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
3197373-2	1988	On two separate occasions, at least 1 week apart, seven young healthy male subjects received intravenous infusions of either adrenaline [0.27 nmol (50 ng) min-1 kg-1] or saline (154 mmol/l NaCl), plus ascorbic acid (5.68 mmol/l), over 30 min.	Epinephrine	125-135	CD59 molecule (CD59 blood group)	Homo sapiens	155-165
2904313-4	1988	Dopamine infusion alone, in doses ranging from 0.25 to 8 micrograms min-1 kg-1, resulted in a dose-dependent increase in effective renal plasma flow (ERPF) and glomerular filtration rate (GFR) with a fall in filtration fraction (FF) in eight hydrated healthy volunteers and, to a lesser degree, in 12 patients with renal disease.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	68-78
3247561-7	1988	Mean values (+/- SD) of D-sorbitol plasma disappearance rate were 0.048 +/- 0.014 min-1 in cirrhotic patients, and 0.081 +/- 0.014 min-1 in normal subjects (p less than 0.001).	Sorbitol	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
3147900-2	1988	Clamp glucose requirement (insulin, 0.1 U kg-1 h-1) was significantly lower in the older subjects (8.0 +/- 0.4 mg kg-1 min-1) than in younger subjects (10.5 +/- 0.6 mg kg-1 min-1, P less than 0.02).	Glucose	6-13	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
3147903-9	1988	The intrinsic hepatic clearance of ICG was on average 0.75 +/- 0.26 l plasma min-1 (+/- SD, n = 20) in controls and 0.39 +/- 0.18 l plasma min-1 in liver patients (n = 41), P less than 0.001.	Indocyanine Green	35-38	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
3206382-3	1988	After allowance for confounding factors the asthmatic subjects had a lower maximum oxygen consumption (VO2 max) (by 199 ml min-1) than control subjects.	Oxygen	83-89	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
2844119-5	1988	Ethylenediaminetetraacetic acid (EDTA) and NTA rapidly remove zinc from ACE with rate constants of 1.27 X 10(3) and 2.2 X 10(3) M-1 min-1.	Edetic Acid	0-31	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
3239422-6	1988	At rest, the thus corrected renal venous overflows of NA and DA were 228 +/- 34 and 29 +/- 3 pmol min-1, respectively.	Dopamine	61-63	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
2844119-5	1988	Ethylenediaminetetraacetic acid (EDTA) and NTA rapidly remove zinc from ACE with rate constants of 1.27 X 10(3) and 2.2 X 10(3) M-1 min-1.	Edetic Acid	33-37	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
2844119-5	1988	Ethylenediaminetetraacetic acid (EDTA) and NTA rapidly remove zinc from ACE with rate constants of 1.27 X 10(3) and 2.2 X 10(3) M-1 min-1.	Nitrilotriacetic Acid	43-46	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
2852498-7	1988	The inhibition rate of APC by PCI (k: 7.5 x 10(5) M-1 min-1) is significantly increased in the presence of 5 i.u./ml heparin (kH: 2.2 x 10(7) M-1 min-1).	Heparin	117-124	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
2852498-7	1988	The inhibition rate of APC by PCI (k: 7.5 x 10(5) M-1 min-1) is significantly increased in the presence of 5 i.u./ml heparin (kH: 2.2 x 10(7) M-1 min-1).	Heparin	117-124	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
3046824-10	1988	Mean peak plasma isoprenaline levels were 0.16 +/- 0.02 nmol/l during the 5 ng min-1 kg-1 infusion and 0.71 +/- 0.05 nmol/l during the 15 ng min-1 kg-1 infusion.	Isoproterenol	17-29	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
3179149-3	1988	During neuroleptanalgesia, droperidol kinetics were linear over the dose range tested: the overall mean elimination half-life was 127 min, Vdss 103 litre and the plasma clearance 732 ml min-1.	Droperidol	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
3179169-9	1988	The persistence of hydroxychloroquine in the body is due primarily to this extensive tissue distribution, rather than to low clearance (667 ml min-1 based on plasma data, 96 ml min-1 based on blood data).	Hydroxychloroquine	19-37	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
3179169-9	1988	The persistence of hydroxychloroquine in the body is due primarily to this extensive tissue distribution, rather than to low clearance (667 ml min-1 based on plasma data, 96 ml min-1 based on blood data).	Hydroxychloroquine	19-37	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
3168130-2	1988	Atropine produced a significant increase in heart rate (HR) within 1 min in all patients studied; the HR increases in patients anaesthetized with halothane (37 +/- 11 beats.min-1, n = 37) or narcotic (34 +/- 12 beats.min-1, n = 30) were significantly greater than in those anaesthetized with enflurane (25 +/- 10 beats.min-1, n = 35; P less than 0.01) or epidural anaesthesia.	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
3168130-2	1988	Atropine produced a significant increase in heart rate (HR) within 1 min in all patients studied; the HR increases in patients anaesthetized with halothane (37 +/- 11 beats.min-1, n = 37) or narcotic (34 +/- 12 beats.min-1, n = 30) were significantly greater than in those anaesthetized with enflurane (25 +/- 10 beats.min-1, n = 35; P less than 0.01) or epidural anaesthesia.	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	217-222
3168130-2	1988	Atropine produced a significant increase in heart rate (HR) within 1 min in all patients studied; the HR increases in patients anaesthetized with halothane (37 +/- 11 beats.min-1, n = 37) or narcotic (34 +/- 12 beats.min-1, n = 30) were significantly greater than in those anaesthetized with enflurane (25 +/- 10 beats.min-1, n = 35; P less than 0.01) or epidural anaesthesia.	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	217-222
3176833-8	1988	Thus, PBF was 961 +/- 119 ml.min-1 during control conditions and increased to 1446 +/- 221 ml.min-1 during the dopamine infusion at 6 micrograms.kg-1.min-1.	Dopamine	111-119	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
3138512-4	1988	The rate of glucose disappearance (RdG) increased from 2.41 +/- 0.40 at rest to 3.38 +/- 0.77 mg x kg-1 x min-1 during exercise, compared with the much larger rise in the rate of lactate appearance (RaL), which increased from 1.25 +/- 0.20 to 3.47 +/- 0.79 mg x kg-1 x min-1.	Glucose	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
3138512-4	1988	The rate of glucose disappearance (RdG) increased from 2.41 +/- 0.40 at rest to 3.38 +/- 0.77 mg x kg-1 x min-1 during exercise, compared with the much larger rise in the rate of lactate appearance (RaL), which increased from 1.25 +/- 0.20 to 3.47 +/- 0.79 mg x kg-1 x min-1.	Glucose	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	269-274
3138512-6	1988	The rate at which the blood was cleared of lactate increased from 22.7 +/- 2.2 at rest to 44.2 +/- 11.2 ml x kg-1 x min-1 after 25 minutes of exercise.	Lactic Acid	43-50	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
3138512-7	1988	From secondary labeling of lactate with glucose carbons, the rate of glucose conversion to lactate was estimated to be 0.65 +/- 0.16 mg x kg-1 x min-1 during exercise.	Lactic Acid	27-34	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
3138512-7	1988	From secondary labeling of lactate with glucose carbons, the rate of glucose conversion to lactate was estimated to be 0.65 +/- 0.16 mg x kg-1 x min-1 during exercise.	Glucose	69-76	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
3138512-7	1988	From secondary labeling of lactate with glucose carbons, the rate of glucose conversion to lactate was estimated to be 0.65 +/- 0.16 mg x kg-1 x min-1 during exercise.	Lactic Acid	91-98	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
3176833-8	1988	Thus, PBF was 961 +/- 119 ml.min-1 during control conditions and increased to 1446 +/- 221 ml.min-1 during the dopamine infusion at 6 micrograms.kg-1.min-1.	Dopamine	111-119	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
3052169-7	1988	With pentazocine, an average of 144 micrograms kg-1 min-1 was administered during the first 16 h after the operation; with Fentanyl, the quantity taken was 0.78 microgram kg-1 min-1.	Pentazocine	5-16	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
3052169-7	1988	With pentazocine, an average of 144 micrograms kg-1 min-1 was administered during the first 16 h after the operation; with Fentanyl, the quantity taken was 0.78 microgram kg-1 min-1.	Fentanyl	123-131	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
3207554-2	1988	Chloroquine was found to be excreted into semen with a slow transfer rate constant of 0.0002 min-1, and the semen/plasma ratio based on regression analysis was 0.40 +/- 0.06 (mean +/- s.d.).	Chloroquine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
3173047-5	1988	Triathlon running, while performing identical control work output, elicited significant increases (P less than 0.05) in oxygen uptake (3.41 +/- 0.1 to 3.85 +/- 0.1 l.min-1), ventilation (91.3 +/- 3.3 to 104.2 +/- 2.8 l.min-1), heart rate (161 +/- 3.1 to 174 +/- 3.6 beats.min-1), arteriovenous oxygen difference (15.3 +/- 0.2 to 17.2 +/- 0.3 ml.100 ml-1) and rectal temperature (38.3 +/- 0.2 and 39.2 +/- 0.3 degrees C) with significantly lower (P less than 0.05) stroke volume (138 +/- 2.4 to 129 +/- 3.6 ml.min-1) and mean arterial pressure (102 +/- 11.2 to 89 +/- 5.5 mm Hg).	Oxygen	120-126	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
3394823-4	1988	In hypertensive patients, norepinephrine (40 ng.kg-1.min-1) induced 1) a significant decrease in brachial artery diameter, local blood velocity, volumic flow, and conductance and 2) a small increase in mean arterial pressure.	Norepinephrine	26-40	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
3170719-3	1988	Nearly 12 liters of flowing blood (up to 200 ml min-1; mean running time, 60 min) came in contact with the coated charcoal.	coated	107-113	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
3384824-11	1988	The enzyme did, however, hydrolyze monoacylglycerol although at a rate 20-fold less than lysophospholipid, 0.06 mumol min-1mg-1.	Monoglycerides	35-51	CD59 molecule (CD59 blood group)	Homo sapiens	118-127
3384824-11	1988	The enzyme did, however, hydrolyze monoacylglycerol although at a rate 20-fold less than lysophospholipid, 0.06 mumol min-1mg-1.	Lysophospholipids	89-105	CD59 molecule (CD59 blood group)	Homo sapiens	118-127
2846108-8	1988	In the absence of calcium and in the presence of EGTA (1 mM), permeabilised 7315c cells secreted prolactin at a rate of 0.23 ng min-1 per 10(6) cells.	Egtazic Acid	49-53	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
2846108-9	1988	When EGTA was replaced by 1.5 mM calcium, permeabilised cells secreted prolactin at a rate of 2.20 +/- 0.30 ng min-1 per 10(6) cells in the first 5 min of exposure.	Egtazic Acid	5-9	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
2846108-9	1988	When EGTA was replaced by 1.5 mM calcium, permeabilised cells secreted prolactin at a rate of 2.20 +/- 0.30 ng min-1 per 10(6) cells in the first 5 min of exposure.	Calcium	33-40	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
2904825-9	1988	For bisoprolol, the median clearance fell from 264 ml min-1 after a single dose to 212 ml min-1 during chronic dosing, although clinically significant accumulation would not be expected during chronic administration.	Bisoprolol	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
2904825-9	1988	For bisoprolol, the median clearance fell from 264 ml min-1 after a single dose to 212 ml min-1 during chronic dosing, although clinically significant accumulation would not be expected during chronic administration.	Bisoprolol	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
2968875-8	1988	The apparent nonrenal clearance, 40 ml/min 1.73 m2, probably reflects sequestration of foscarnet into bone.	Foscarnet	87-96	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
3409985-7	1988	The mean endothelial permeability to fluorescein was 4.03 +/- 0.63 x 10(-4) cm min-1.	Fluorescein	37-48	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
3209978-7	1988	Each jaw secretes at an average rate of 230 nl min-1 in the presence of serotonin, and secretion is completely abolished by cobalt.	Serotonin	72-81	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
3292681-4	1988	In addition, the rate of activation of glucose utilization (slope 0 to 90 minutes) was decreased (p less than 0.02) in the type I patients compared with subjects without diabetes during both the constant (0.003 +/- 0.001 mg/kg/min 2 vs 0.008 +/- 0.002 mg/kg/min 2) and variable (0.006 +/- 0.002 mg/kg/min 2 vs 0.015 +/- 0.002 mg/kg/min 2) insulin infusions.	Glucose	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	227-232
3292681-4	1988	In addition, the rate of activation of glucose utilization (slope 0 to 90 minutes) was decreased (p less than 0.02) in the type I patients compared with subjects without diabetes during both the constant (0.003 +/- 0.001 mg/kg/min 2 vs 0.008 +/- 0.002 mg/kg/min 2) and variable (0.006 +/- 0.002 mg/kg/min 2 vs 0.015 +/- 0.002 mg/kg/min 2) insulin infusions.	Glucose	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	258-263
3292681-4	1988	In addition, the rate of activation of glucose utilization (slope 0 to 90 minutes) was decreased (p less than 0.02) in the type I patients compared with subjects without diabetes during both the constant (0.003 +/- 0.001 mg/kg/min 2 vs 0.008 +/- 0.002 mg/kg/min 2) and variable (0.006 +/- 0.002 mg/kg/min 2 vs 0.015 +/- 0.002 mg/kg/min 2) insulin infusions.	Glucose	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	258-263
3292681-4	1988	In addition, the rate of activation of glucose utilization (slope 0 to 90 minutes) was decreased (p less than 0.02) in the type I patients compared with subjects without diabetes during both the constant (0.003 +/- 0.001 mg/kg/min 2 vs 0.008 +/- 0.002 mg/kg/min 2) and variable (0.006 +/- 0.002 mg/kg/min 2 vs 0.015 +/- 0.002 mg/kg/min 2) insulin infusions.	Glucose	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	258-263
3184250-4	1988	When the subject can no longer follow the pace, the last stage number announced is used to predict maximal oxygen uptake (VO2max) (Y, ml kg-1 min-1) from the speed (X, km h-1) corresponding to that stage (speed = 8 + 0.5 stage no.)	Oxygen	107-113	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
3288006-3	1988	Isoflurane seemed to induce glucose intolerance (glucose disappearance rate K10-60 min = 1.628 +/- 0.462% min-1 [control] versus 1.086 +/- 0.920% min-1 [anesthesia], P less than 0.05) partly due to a decreased glucose induced insulin response.	Isoflurane	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
3288006-3	1988	Isoflurane seemed to induce glucose intolerance (glucose disappearance rate K10-60 min = 1.628 +/- 0.462% min-1 [control] versus 1.086 +/- 0.920% min-1 [anesthesia], P less than 0.05) partly due to a decreased glucose induced insulin response.	Isoflurane	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
3288006-3	1988	Isoflurane seemed to induce glucose intolerance (glucose disappearance rate K10-60 min = 1.628 +/- 0.462% min-1 [control] versus 1.086 +/- 0.920% min-1 [anesthesia], P less than 0.05) partly due to a decreased glucose induced insulin response.	Glucose	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
3288006-6	1988	Although glucose intolerance was marked during surgery (K10-60 min = 0.892 +/- 0.286% min-1), the glucose-induced insulin response remained similar to that observed in patients in group II, while growth hormone, cortisol, epinephrine, and norepinephrine concentrations increased significantly.	Glucose	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
3285136-4	1988	In the normoglycemic state, endogenous glucose production averaged 2.15 +/- 0.13 mg x kg-1 x min-1.	Glucose	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
2968766-7	1988	Fifty percent of the Cl- efflux occurs via an anion exchange pathway having an efflux constant of 0.040 min-1 that is inhibited by DIDS or by removal of Cl- from the extracellular medium.	4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid	131-135	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
3167503-7	1988	Predicted mean gross values of oxygen consumption for the males were 42.8 +/- 5.7 ml.kg-1 min-1 and 42.8 +/- 6.9 ml.kg-1 min-1 for the Modern and Latin American sequences respectively.	Oxygen	31-37	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
3167503-8	1988	Corresponding gross estimates of oxygen consumption for the females were 34.7 +/- 3.8 ml.kg-1 min-1 and 36.1 +/- 4.1 ml.kg-1 min-1.	Oxygen	33-39	CD59 molecule (CD59 blood group)	Homo sapiens	94-108
3167503-8	1988	Corresponding gross estimates of oxygen consumption for the females were 34.7 +/- 3.8 ml.kg-1 min-1 and 36.1 +/- 4.1 ml.kg-1 min-1.	Oxygen	33-39	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
3167503-11	1988	A significant difference between males and females was observed for predicted gross and net values of oxygen consumption (in L.min-1 and ml.kg-1 min-1).	Oxygen	102-108	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
3167503-11	1988	A significant difference between males and females was observed for predicted gross and net values of oxygen consumption (in L.min-1 and ml.kg-1 min-1).	Oxygen	102-108	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
3203043-6	1988	After high-dose nisoldipine, systemic clearance was 0.99 +/- 0.16 1 min-1, volume of distribution was 5.8 +/- 1.5 1 kg-1 and elimination half-life was 10.7 +/- 2.4 h. The pharmacokinetic parameters were similar after low-dose nisoldipine.	Nisoldipine	16-27	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
3293731-4	1988	Studies of subjects from various countries report aerobic power generally between 40 and 50 mL O2/kg.min-1, with a mean around 45 mL.	Oxygen	95-97	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
2843379-3	1988	Intra-arterial phenylephrine (0.2-1.3 micrograms min-1) and clonidine (0.12-0.48 micrograms min-1) produced dose-related decreases in finger blood flow and increases in vascular resistance.	Phenylephrine	15-28	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
2843379-3	1988	Intra-arterial phenylephrine (0.2-1.3 micrograms min-1) and clonidine (0.12-0.48 micrograms min-1) produced dose-related decreases in finger blood flow and increases in vascular resistance.	Clonidine	60-69	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
2843379-5	1988	Prazosin (0.4-3 micrograms min-1) effectively blocked the vasoconstrictor effect of phenylephrine but not clonidine, while yohimbine (30-70 micrograms min-1) blocked the effect of clonidine but not phenylephrine.	Prazosin	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
2843379-5	1988	Prazosin (0.4-3 micrograms min-1) effectively blocked the vasoconstrictor effect of phenylephrine but not clonidine, while yohimbine (30-70 micrograms min-1) blocked the effect of clonidine but not phenylephrine.	Phenylephrine	84-97	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
2843379-5	1988	Prazosin (0.4-3 micrograms min-1) effectively blocked the vasoconstrictor effect of phenylephrine but not clonidine, while yohimbine (30-70 micrograms min-1) blocked the effect of clonidine but not phenylephrine.	Yohimbine	123-132	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
2843379-6	1988	In a 20 degrees C room, prazosin (0.4-13.2 micrograms min-1) caused no significant changes in finger blood flow (7.7 +/- 2.1 to 11.7 +/- 3.3 ml min-1 100 ml-1) or vascular resistance (30.9 +/- 8.8 to 28.1 +/- 8.7 mmHg ml-1 min-1 100 ml-1).	Prazosin	24-32	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
2843379-7	1988	In the 20 degrees C room, yohimbine (30-70 micrograms min-1) produced a significant increase in finger blood flow (7.8 +/- 2.8 to 23.4 +/- 6.8 ml, P less than 0.01) and decrease in vascular resistance (20.5 +/- 5.7 to 6.0 +/- 2.2 units, P less than 0.01).	Yohimbine	26-35	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
2839411-6	1988	Stimulation of T cells with Con A or with the combination of ionomycin plus phorbol myristate acetate produced a marked increase of TAP expression.	Ionomycin	61-70	CD59 molecule (CD59 blood group)	Homo sapiens	132-135
2839411-6	1988	Stimulation of T cells with Con A or with the combination of ionomycin plus phorbol myristate acetate produced a marked increase of TAP expression.	Tetradecanoylphorbol Acetate	76-101	CD59 molecule (CD59 blood group)	Homo sapiens	132-135
3195806-3	1988	VO2max (mean value, 1.38 L min-1) was described by FEV1 and single-breath lung transfer factor (diffusing capacity) for carbon monoxide (TL") singly or in combination, but the accuracy was poor (at best, standard error of the estimate, 0.36 L min-1; r2, 29.1%).	Carbon Monoxide	120-135	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
3195806-3	1988	VO2max (mean value, 1.38 L min-1) was described by FEV1 and single-breath lung transfer factor (diffusing capacity) for carbon monoxide (TL") singly or in combination, but the accuracy was poor (at best, standard error of the estimate, 0.36 L min-1; r2, 29.1%).	Thallium	137-140	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
3377942-6	1988	Stable serum concentrations of fentanyl were produced by the end of surgery and were maintained for a total of 24 h. Calculated clearance of fentanyl was 1.05 +/- 0.38 litre min-1 and was not related to weight or age.	Fentanyl	141-149	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
3395665-4	1988	The basic pharmacokinetic parameters (means +/- SE) of terodiline were calculated to: biological half-life in serum 60 +/- 4 h, maximum serum concentration 79 +/- 4 micrograms l-1 and the corresponding time 4 +/- 1 h, oral serum clearance 75 +/- 7 ml min-1, urinary excretion 15.3 +/- 1.5 per cent of dose, and renal serum clearance 10.9 +/- 2.2 ml min-1.	terodiline	55-65	CD59 molecule (CD59 blood group)	Homo sapiens	251-256
3395665-4	1988	The basic pharmacokinetic parameters (means +/- SE) of terodiline were calculated to: biological half-life in serum 60 +/- 4 h, maximum serum concentration 79 +/- 4 micrograms l-1 and the corresponding time 4 +/- 1 h, oral serum clearance 75 +/- 7 ml min-1, urinary excretion 15.3 +/- 1.5 per cent of dose, and renal serum clearance 10.9 +/- 2.2 ml min-1.	terodiline	55-65	CD59 molecule (CD59 blood group)	Homo sapiens	349-354
2968879-3	1988	In RSA- patients the total power (0.01-0.50 Hz) was significantly reduced compared with control subjects (4.7 versus 15.5 min-2, 2p less than 0.05) and the pattern of heart rate fluctuations was characterized by a relative increase in the low-frequency component (0.01-0.05 Hz) as compared with RSA+ patients and control subjects (45% versus 24% and 27%, both 2p less than 0.01).	rabbit sperm membrane autoantigen	3-6	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
3356110-4	1988	In the control group, the mean (+/- SD) serum caffeine clearance was 1.3 +/- 0.4 ml min-1 kg-1 and a mean of 56.4 +/- 16.5% of the administered caffeine was recovered from the urine over 48 h as methyluric acids and methylxanthines.	Caffeine	46-54	CD59 molecule (CD59 blood group)	Homo sapiens	84-94
3356110-8	1988	Thus the mean serum caffeine clearance was 1.4 +/- 1.2 ml min-1 kg-1 and a mean of 57.2 +/- 11.7% of the administered caffeine was recovered from the urine over 48 h. The majority of the metabolites were excreted in the first 24 h; the pattern of metabolic excretion was unaltered and only 2.2 +/- 0.9% of the administered caffeine was excreted unchanged.	Caffeine	20-28	CD59 molecule (CD59 blood group)	Homo sapiens	58-68
3356110-11	1988	The mean serum caffeine clearance (0.4 +/- 0.2 ml min-1 kg-1) was significantly impaired compared with controls (P less than 0.01) and a significant delay was observed in metabolite excretion in the urine.	Caffeine	15-23	CD59 molecule (CD59 blood group)	Homo sapiens	50-60
3399365-8	1988	O2-consumption (l.min-1) and heart rates (beats.min-1) were similar during outdoor and indoor bicycling, averaging 2.38 +/- 0.018 (SE) and 2.26 +/- 0.07, 141 +/- 7 and 147 +/- 8, respectively.	Oxygen	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	18-23
2837286-3	1988	Phenylglyoxal was 10-fold more effective than pHPG in promoting the loss of CaM-stimulated activity with a second-order rate constant of 13.3 M-1 min-1.	Phenylglyoxal	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
2837286-3	1988	Phenylglyoxal was 10-fold more effective than pHPG in promoting the loss of CaM-stimulated activity with a second-order rate constant of 13.3 M-1 min-1.	4-hydroxyphenylglyoxal	46-50	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
3350018-6	1988	In the presence of dithiothreitol and of reduced corrinoids or titanium(III) citrate the specific rate of CH3-S-CoM reduction to CH4 with H-S-HTP increased to 0.5-2 mumol min-1 mg protein-1.	Dithiothreitol	19-33	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
3350018-6	1988	In the presence of dithiothreitol and of reduced corrinoids or titanium(III) citrate the specific rate of CH3-S-CoM reduction to CH4 with H-S-HTP increased to 0.5-2 mumol min-1 mg protein-1.	Corrinoids	49-59	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
3350018-6	1988	In the presence of dithiothreitol and of reduced corrinoids or titanium(III) citrate the specific rate of CH3-S-CoM reduction to CH4 with H-S-HTP increased to 0.5-2 mumol min-1 mg protein-1.	titanium(iii) citrate	63-84	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
3350018-6	1988	In the presence of dithiothreitol and of reduced corrinoids or titanium(III) citrate the specific rate of CH3-S-CoM reduction to CH4 with H-S-HTP increased to 0.5-2 mumol min-1 mg protein-1.	Sulfur	110-111	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
3355588-5	1988	Mean apparent Km and Vmax values for hydroxytolbutamide formation were 120 +/- 41 microM and 0.273 +/- 0.066 nmol min-1 mg-1, respectively.	hydroxymethyltolbutamide	37-55	CD59 molecule (CD59 blood group)	Homo sapiens	114-124
3348317-7	1988	However, maternal clearance of procainamide (9.7 ml/kg-1/min-1) was twice as long as the clearance reported for nonpregnant patients undergoing fast acetylation.	Procainamide	31-43	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
3125767-2	1988	Lidocaine was infused intravenously to the mother at a constant rate of 0.1 mg.kg-1.min-1 over a period of 180 min, in order to reach a steady-state maternal plasma lidocaine concentration of approximately 2 micrograms/ml.	Lidocaine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
3344997-2	1988	Adenosine was intravenously infused, at a rate of 90 +/- 20 (SEM) micrograms.kg-1.min-1, to reduce mean arterial blood pressure by approximately 20% (23 +/- 2% SEM, from 82 +/- 3 to 63 +/- 3 SEM mmHg) during a 20-min period.	Adenosine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
3348718-6	1988	The average (+/- standard error) maximal oxygen consumption (VO2max) for all players was 53.4 +/- 0.8 ml x kg-1 x min-1.	Oxygen	41-47	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
2896014-7	1988	Mean steady-state fenoldopam plasma concentrations were related to mean PAH clearance based on an Emax model (r = 0.996) with an Emax of 1350 ml min-1 and an EC50 of 6.2 ng ml-1.	Fenoldopam	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
2896014-7	1988	Mean steady-state fenoldopam plasma concentrations were related to mean PAH clearance based on an Emax model (r = 0.996) with an Emax of 1350 ml min-1 and an EC50 of 6.2 ng ml-1.	p-Aminohippuric Acid	72-75	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
3358896-7	1988	Digoxin in increasing doses slowed the heart rate at rest; with the daily dose of 0.50 mg from 63 +/- 10 to 53 +/- 6 beats min-1, and fractional shortening rose from 28 +/- 6 to 33 +/- 3% (P less than 0.05 for both).	Digoxin	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
3358896-13	1988	During autonomic blockade digoxin slowed the intrinsic heart rate from 93 +/- 6 to 86 +/- 6 beats min-1 (0.25 mg) and to 83 +/- 6 beats min-1 (0.50 mg) (P less than 0.01 for both).	Digoxin	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
3358896-13	1988	During autonomic blockade digoxin slowed the intrinsic heart rate from 93 +/- 6 to 86 +/- 6 beats min-1 (0.25 mg) and to 83 +/- 6 beats min-1 (0.50 mg) (P less than 0.01 for both).	Digoxin	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
3358898-4	1988	In normotensive subjects with normal renal function, cicletanine was rapidly and regularly absorbed, its apparent elimination half-life established around 7 h, and both its renal clearance (0.4 ml min-1) and its cumulative renal excretion (0.85% of the administered dose), were low.	cicletanine	53-64	CD59 molecule (CD59 blood group)	Homo sapiens	197-202
3378065-5	1988	The rate constants for the oxidation of the first, of the two first and of the third plus fourth tryptophanyls are equal to 1.5.10(-2) min-1, 1,1.10(-2) min-1 and 0.5.10(-2) min -1, respectively.	tryptophanyls	97-110	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
3378065-5	1988	The rate constants for the oxidation of the first, of the two first and of the third plus fourth tryptophanyls are equal to 1.5.10(-2) min-1, 1,1.10(-2) min-1 and 0.5.10(-2) min -1, respectively.	tryptophanyls	97-110	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
3378065-5	1988	The rate constants for the oxidation of the first, of the two first and of the third plus fourth tryptophanyls are equal to 1.5.10(-2) min-1, 1,1.10(-2) min-1 and 0.5.10(-2) min -1, respectively.	tryptophanyls	97-110	CD59 molecule (CD59 blood group)	Homo sapiens	174-180
3407080-3	1988	Gram-positive microorganisms were found to die in the 30% solution of urea within 30 min.--3 h, gram-negative ones--within 30 min.--1 h. The introduction of urea directly into the purulent infection focus against the background of general therapy allowed to quickly block the acute phase of the suppurative process, to prepare the patients to planned operations and to reduce the amount of postoperative complications as compared with a control group of patients who were treated by routine local antiseptic drugs.	Urea	70-74	CD59 molecule (CD59 blood group)	Homo sapiens	85-92
3407080-3	1988	Gram-positive microorganisms were found to die in the 30% solution of urea within 30 min.--3 h, gram-negative ones--within 30 min.--1 h. The introduction of urea directly into the purulent infection focus against the background of general therapy allowed to quickly block the acute phase of the suppurative process, to prepare the patients to planned operations and to reduce the amount of postoperative complications as compared with a control group of patients who were treated by routine local antiseptic drugs.	Urea	157-161	CD59 molecule (CD59 blood group)	Homo sapiens	85-92
3407080-3	1988	Gram-positive microorganisms were found to die in the 30% solution of urea within 30 min.--3 h, gram-negative ones--within 30 min.--1 h. The introduction of urea directly into the purulent infection focus against the background of general therapy allowed to quickly block the acute phase of the suppurative process, to prepare the patients to planned operations and to reduce the amount of postoperative complications as compared with a control group of patients who were treated by routine local antiseptic drugs.	Urea	157-161	CD59 molecule (CD59 blood group)	Homo sapiens	126-133
3341836-1	1988	Thirty-five patients with severe chronic congestive heart failure that was refractory to conventional therapy were given high dosages of furosemide (250 to 4000 mg/d) because of significantly reduced renal function (mean endogenous creatinine clearance, 0.53 mL/s/1.73 m2 [32 mL/min/1.73 m2]).	Furosemide	137-147	CD59 molecule (CD59 blood group)	Homo sapiens	279-284
2896012-9	1988	The renal clearance of xamoterol was lower in the elderly (115 +/- 12 vs 185 +/- 19 ml min-1) and showed a significant correlation with creatinine clearance (r = 0.85, P less than 0.001).	Xamoterol	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
3257879-5	1988	The clearance of propofol was significantly lower in the elderly (1.44 +/- 0.10 (SE) litre min-1) than in the younger patients (1.79 +/- 0.12 litre min-1).	Propofol	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
3257879-5	1988	The clearance of propofol was significantly lower in the elderly (1.44 +/- 0.10 (SE) litre min-1) than in the younger patients (1.79 +/- 0.12 litre min-1).	Propofol	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
2827913-3	1988	To minimize peripheral effects, a bilateral intracoronary infusion of enalaprilat (0.05 mg.min-1, 1 ml.min-1 in each coronary artery) was performed in 16 patients with dilated cardiomyopathy.	Enalaprilat	70-81	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
2827913-3	1988	To minimize peripheral effects, a bilateral intracoronary infusion of enalaprilat (0.05 mg.min-1, 1 ml.min-1 in each coronary artery) was performed in 16 patients with dilated cardiomyopathy.	Enalaprilat	70-81	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
3349759-5	1988	The rate of oxygen uptake under maximum exercise was low (26 ml/min-1/kg-1) and was not significantly increased at test 2 and 3.	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
2832173-5	1988	Treatment with enalapril, in the absence of frusemide, was associated with a fall in mean blood pressure from 89 +/- 5 mmHg to 85 +/- 4 mmHg (P less than 0.02) and a rise in renal blood flow from 424 +/- 202 ml min-1 to 494 +/- 225 ml min-1 (P less than 0.02), but cardiac output and glomerular filtration rate were again unchanged.	Enalapril	15-24	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
2832173-5	1988	Treatment with enalapril, in the absence of frusemide, was associated with a fall in mean blood pressure from 89 +/- 5 mmHg to 85 +/- 4 mmHg (P less than 0.02) and a rise in renal blood flow from 424 +/- 202 ml min-1 to 494 +/- 225 ml min-1 (P less than 0.02), but cardiac output and glomerular filtration rate were again unchanged.	Enalapril	15-24	CD59 molecule (CD59 blood group)	Homo sapiens	235-240
2832173-6	1988	Addition of frusemide to enalapril therapy resulted in a greater fall in mean blood pressure (87 +/- 5 mmHg to 79 +/- 4 mmHg; P less than 0.01) and an increase in cardiac output (3.1 +/- 1.1 l min-1 to 3.6 +/- 1.0 l min-1; P less than 0.02).	Furosemide	12-21	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
2832173-6	1988	Addition of frusemide to enalapril therapy resulted in a greater fall in mean blood pressure (87 +/- 5 mmHg to 79 +/- 4 mmHg; P less than 0.01) and an increase in cardiac output (3.1 +/- 1.1 l min-1 to 3.6 +/- 1.0 l min-1; P less than 0.02).	Furosemide	12-21	CD59 molecule (CD59 blood group)	Homo sapiens	216-221
3130261-5	1988	Efflux of tyrosine from leg tissues was six-fold greater in patients with untreated thyrotoxicosis than in normal control subjects (-19.39 +/- 2.21 vs. -4.20 +/- 0.31 nmol 100 g-1 leg tissue min-1, P less than 0.005, mean +/- SEM), but 3-methyl-histidine efflux was not significantly different (-0.11 +/- 0.03 nmol 100 g-1 leg tissue min-1 vs. 0.14 +/- 0.02 nmol 100 g-1 leg tissue min-1).	Tyrosine	10-18	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
3130261-5	1988	Efflux of tyrosine from leg tissues was six-fold greater in patients with untreated thyrotoxicosis than in normal control subjects (-19.39 +/- 2.21 vs. -4.20 +/- 0.31 nmol 100 g-1 leg tissue min-1, P less than 0.005, mean +/- SEM), but 3-methyl-histidine efflux was not significantly different (-0.11 +/- 0.03 nmol 100 g-1 leg tissue min-1 vs. 0.14 +/- 0.02 nmol 100 g-1 leg tissue min-1).	Tyrosine	10-18	CD59 molecule (CD59 blood group)	Homo sapiens	334-339
3130261-5	1988	Efflux of tyrosine from leg tissues was six-fold greater in patients with untreated thyrotoxicosis than in normal control subjects (-19.39 +/- 2.21 vs. -4.20 +/- 0.31 nmol 100 g-1 leg tissue min-1, P less than 0.005, mean +/- SEM), but 3-methyl-histidine efflux was not significantly different (-0.11 +/- 0.03 nmol 100 g-1 leg tissue min-1 vs. 0.14 +/- 0.02 nmol 100 g-1 leg tissue min-1).	Tyrosine	10-18	CD59 molecule (CD59 blood group)	Homo sapiens	334-339
3130261-6	1988	After treatment, when the thyrotoxic patients became euthyroid, tyrosine efflux was normalized (at -4.94 +/- 0.84 nmol 100 g-1 leg tissue min-1) and 3-methylhistidine efflux was unchanged.	Tyrosine	64-72	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
3343911-5	1988	Exercise oxygen consumption averaged 1.54 l.min-1 across all experiments and was equivalent to 60% of arm and 37% of leg peak values.	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
2829392-3	1988	Although much more stable at physiological pH than its 4-nitrophenyl analogue, this ester is a good inhibitor of neuropathy target esterase (NTE): kappa a = 1.7 X 10(5) M-1 min-1.	Esters	84-89	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
3278496-5	1988	mean) determined prior to administration of volatile agents were 28 +/- 5 ml x 100(-1) x min-1 and 2.0 +/- 0.3 ml x 100 g-1 x min-1, respectively, in the isoflurane group.	Isoflurane	154-164	CD59 molecule (CD59 blood group)	Homo sapiens	89-102
3059852-7	1988	After the administration of pancuronium (0.15 mg.kg-1), the patients in group P showed a significant increase in heart rate (+ 14 b.min-1), accompanied by an increase in cardiac index (+0.45 l.min-1.m-2).	Pancuronium	28-39	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
3059852-7	1988	After the administration of pancuronium (0.15 mg.kg-1), the patients in group P showed a significant increase in heart rate (+ 14 b.min-1), accompanied by an increase in cardiac index (+0.45 l.min-1.m-2).	Pancuronium	28-39	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
3130890-4	1988	3 Atropine significantly reduced salivary output (-2.25 +/- 0.36 ml from control values of 4.17 +/- 0.42 ml, P less than 0.001) and heart rate (-9.7 +/- 3.7 beats min-1 from 77.5 +/- 2.7, P less than 0.05).	Atropine	2-10	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
3075149-4	1988	Phosphate excretion showed an initial fall followed by a more than twofold increase afterwards (6.52 +/- 0.92 vs. 3.14 +/- 0.92 and 15.29 +/- 3.82 mumol/min/1.73 m2, respectively).	Phosphates	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
3123118-4	1988	Gludopa is natriuretic and diuretic at a dose of 25 micrograms min-1 kg-1.	gamma-glutamyl DOPA	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	63-73
3416723-2	1988	The pharmacokinetics of cicletanine were markedly altered in patients with severe impairment of renal function (i.e., creatinine clearance under 30 ml/min/1.73 m2 or treated by chronic haemodialysis) with a significant increase in elimination half-life and tissue accumulation of the drug.	cicletanine	24-35	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
3416723-4	1988	In conclusion, the use of cicletanine should be restricted, on the basis of these pharmacokinetic data, to chronic uremic patients whose creatinine clearance is 30 ml/min/1.73 m2 or more.	cicletanine	26-37	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
2897913-5	1988	The mean total dose of vecuronium was lower in the patients with biliary obstruction (1.2 +/- 0.1 micrograms kg-1 min-1) than in the elderly patients (1.7 +/- 0.2 micrograms kg-1 min-1) and young patients (2.0 +/- 0.2 micrograms kg-1 min-1; P less than 0.05).	Vecuronium Bromide	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
2897913-5	1988	The mean total dose of vecuronium was lower in the patients with biliary obstruction (1.2 +/- 0.1 micrograms kg-1 min-1) than in the elderly patients (1.7 +/- 0.2 micrograms kg-1 min-1) and young patients (2.0 +/- 0.2 micrograms kg-1 min-1; P less than 0.05).	Vecuronium Bromide	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
2897913-5	1988	The mean total dose of vecuronium was lower in the patients with biliary obstruction (1.2 +/- 0.1 micrograms kg-1 min-1) than in the elderly patients (1.7 +/- 0.2 micrograms kg-1 min-1) and young patients (2.0 +/- 0.2 micrograms kg-1 min-1; P less than 0.05).	Vecuronium Bromide	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
2900756-16	1988	After physostigmine, seven patients had an increase in heart rate to 140 beats min-1 and blood pressure decreased in three patients.	Physostigmine	6-19	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
2906874-6	1988	A significant reduction in heart rate by 10 beats.min-1 was observed with the ketanserin + beta-blocker combination.	Ketanserin	78-88	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
3069478-7	1988	The mean ceftazidime elimination half-life, apparent volume of distribution and total clearance were: 2.7 h, 30.91 (0.38 1.kg-1) and 139 ml.min-1, respectively.	Ceftazidime	9-20	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
3069478-8	1988	A linear correlation was found between creatinine clearance and the renal clearance of the ceftazidime, the mean values being 108 and 95 ml.min-1, respectively.	Creatinine	39-49	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
3069478-8	1988	A linear correlation was found between creatinine clearance and the renal clearance of the ceftazidime, the mean values being 108 and 95 ml.min-1, respectively.	Ceftazidime	91-102	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
3137066-3	1988	They were divided into two groups to receive either nitroglycerin (1 microgram kg-1 min-1) or placebo (5% dextrose).	Nitroglycerin	52-65	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
3220063-5	1988	The urinary Mg2+ excretion rate decreased (p less than 0.001) from 29 +/- 13 to 5 +/- 3 mumol.min-1 during the marathon and increased (p less than 0.05) 12 h after the race to 38 +/- 18 mumol.min-1.	magnesium ion	12-16	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
3220063-5	1988	The urinary Mg2+ excretion rate decreased (p less than 0.001) from 29 +/- 13 to 5 +/- 3 mumol.min-1 during the marathon and increased (p less than 0.05) 12 h after the race to 38 +/- 18 mumol.min-1.	magnesium ion	12-16	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
3264245-6	1988	ketorolac were characterized by a terminal half-life of 5.09 h, a small plasma clearance (CL = 0.35 ml.min-1.kg-1) and a small tissue distribution (Vss = 0.11 l.kg-1, V beta = 0.17 l.kg-1; mean (SD).	Ketorolac	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
3045295-23	1988	kg-1 min-1) on both days and also received an intravenous infusion of saralasin acetate (50 ng kg-1 min-1) plus carrier on one day and carrier alone on the other.	Saralasin	70-87	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
3121596-6	1987	The Km and Vmax for mono(ADP-ribosyl)ation of kemptide are approximately 4.3 +/- 1.2 mM and 38.1 +/- 5.5 nmol min-1 mg-1, respectively.	kemptide	46-54	CD59 molecule (CD59 blood group)	Homo sapiens	110-120
3327362-5	1987	Following saline, adenosine (up to 120 micrograms kg-1 min-1) caused a dose-related increase in heart rate (mean +/- SD maximum increase 18 +/- 8 bpm; P less than 0.01).	Adenosine	18-27	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
3122806-4	1987	We intended to start an infusion of propofol 100 micrograms kg-1 min-1; maintain it for at least 25 min; make a first set of quasi-steady-state observations; double the infusion; and repeat observations after 25 min.	Propofol	36-44	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
3435817-3	1987	Mean maximal oxygen uptake of the men was 42.1 +/- 8.9 ml.kg-1min-1 with mean values of 41.5 +/- 8.7 ml.kg-1min-1 for the women.	Oxygen	13-19	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
3440094-3	1987	We sought evidence for such an effect in man by examining how a subpressor dose of angiotensin II (1.5 ng kg-1 min-1) influences the haemodynamic and plasma noradrenaline responses to physiological stimulation of the sympathetic nervous system.	Norepinephrine	157-170	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
3440102-2	1987	After placebo, adenosine induced an increase of minute ventilation (from 6.3 to 12.5 l min-1), tidal volume (from 0.60 to 0.96 l), and breathing rate (from 11.0 to 14.8 min-1).	Adenosine	15-24	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
3440102-2	1987	After placebo, adenosine induced an increase of minute ventilation (from 6.3 to 12.5 l min-1), tidal volume (from 0.60 to 0.96 l), and breathing rate (from 11.0 to 14.8 min-1).	Adenosine	15-24	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
3330526-3	1987	The rise of heart rate induced by orthostasis was diminished by AQ-A 39 to 4 +/- 2 beats min-1 and by propranolol 9 +/- 2 beats min-1.	aq-a	64-68	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
3330526-3	1987	The rise of heart rate induced by orthostasis was diminished by AQ-A 39 to 4 +/- 2 beats min-1 and by propranolol 9 +/- 2 beats min-1.	Propranolol	102-113	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
3330526-4	1987	After submaximal exercise heart rate during placebo was 129 +/- 3, during AQ-A 39 113 +/- 3 and during propranolol 103 +/- beats min-1.	Propranolol	103-114	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
3330526-9	1987	The dose of isoproterenol necessary to induce an increase of heart rate by 20 beats min-1 was after AQ-A 39 4.2 times greater and following propranolol 9.2 times greater than during placebo.	Isoproterenol	12-25	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
3330526-9	1987	The dose of isoproterenol necessary to induce an increase of heart rate by 20 beats min-1 was after AQ-A 39 4.2 times greater and following propranolol 9.2 times greater than during placebo.	aq-a	100-104	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
3502542-8	1987	The mean heart rate tended to be lower in the alinidine group (82 +/- 12 beats min-1 91 +/- 21 beats min-1.	alinidine	46-55	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
3502542-8	1987	The mean heart rate tended to be lower in the alinidine group (82 +/- 12 beats min-1 91 +/- 21 beats min-1.	alinidine	46-55	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
3502542-9	1987	In 1/16 patients the alinidine treatment was stopped due to marked hypotension (less than 90 mmHg) and bradycardia (less than beats min-1).	alinidine	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
3325487-4	1987	The lactate threshold was assessed in terms of both the absolute work rate (ml.kg-1.min-1) and relative work rate.	Lactic Acid	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
3425344-6	1987	When the power output of the bicycle ergometer was increased from 146 +/- 15 to 283 +/- 17 W, oxygen consumption increased from 2.20 +/- 0.98 to 4.22 +/- 0.20 l min-1 (P less than 0.001), while the oxygen consumption at rest was 0.30 +/- 0.03 l min-1.	Oxygen	94-100	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
2893636-11	1987	Ketanserin treatment was associated with significant changes in supine pulse rate (-8 beats min-1, P less than 0.05) and corrected QT interval (+27 ms, P less than 0.05).	Ketanserin	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
2893637-3	1987	The mean total body clearance of theophylline was reduced from 57.6 ml min-1 before cimetidine to 39.5 ml min-1 during cimetidine; and the half-life was prolonged from 8.7 h before cimetidine to 12 h during cimetidine.	Theophylline	33-45	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
2893637-3	1987	The mean total body clearance of theophylline was reduced from 57.6 ml min-1 before cimetidine to 39.5 ml min-1 during cimetidine; and the half-life was prolonged from 8.7 h before cimetidine to 12 h during cimetidine.	Theophylline	33-45	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
3325091-7	1987	Epoprostenol was administered at a fixed dose of 5 mg kg-1 min-1 for 0.5-24 h daily for 3-7 days.	Epoprostenol	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
3691560-5	1987	Similarly, the anterograde Wenckebach point occurred at a significantly (P less than 0.06) higher rate after falipamil (+10 +/- 7 beats min-1).	falipamil	109-118	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
3665926-13	1987	The specific nitrite-reducing activity with ascorbate-reduced phenazine methosulfate as electron donor was 1 mumol substrate min-1 mg protein-1.	Nitrites	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
3665926-13	1987	The specific nitrite-reducing activity with ascorbate-reduced phenazine methosulfate as electron donor was 1 mumol substrate min-1 mg protein-1.	Ascorbic Acid	44-53	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
3665926-13	1987	The specific nitrite-reducing activity with ascorbate-reduced phenazine methosulfate as electron donor was 1 mumol substrate min-1 mg protein-1.	Methylphenazonium Methosulfate	62-84	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
3675576-3	1987	In a reconstituted system, P-450-ALC oxidizes ethanol and aniline at turnover rates (12.2 and 7.3 nmol min-1, respectively) 10-fold greater than two other human P-450 isozymes (termed P-450-B and P-450-C) purified from the same liver.	aniline	58-65	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
3675584-2	1987	In the presence of polyaspartic acid, the HCII/thrombin reaction is accelerated more than 1000-fold with the second-order rate constant increasing from 3.2 x 10(4) M-1 min-1 (in the absence of polyAsp) to 3.6 x 10(7) M-1 min-1 as the polyAsp concentration is increased from 1 to 250 micrograms/ml.	polyaspartate	19-36	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
3310899-3	1987	Diethyl pyrocarbonate inactivated this enzyme with a second-order rate constant of 220 M-1 min-1 at pH 7.0 and 0 degrees C. The rate of inactivation is pH dependent and the pH inactivation rate data show the involvement of a group with a pKa of 6.8.	Diethyl Pyrocarbonate	0-21	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
3500764-6	1987	Maintenance was extremely smooth with propofol (0.088 mg.kg-1.min-1) in 18 cases.	Propofol	38-46	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
2825746-6	1987	The intravenous data demonstrated that nedocromil sodium is a high clearance drug (10.2 +/- 1.3 ml min-1 kg-1).	Nedocromil	39-56	CD59 molecule (CD59 blood group)	Homo sapiens	99-109
3683155-4	1987	The maximal oxygen uptake achieved in low walking (60.0 +/- 5.8 ml.kg-1.min-1) was not significantly different to that achieved during speed skating (62.1 +/- 6.9), but the maximal level attained in dry skating (48.4 +/- 5.5) was significantly less than both of these.	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
2445500-6	1987	The permeabilized cells incorporated deoxyribonucleotides ([methyl -3H]-TTP) into DNA at a linear rate of 0.047 nmol per 10(7) cells min-1, representing 90-100 per cent of the DNA synthesis rate in vivo.	Deoxyribonucleotides	37-57	CD59 molecule (CD59 blood group)	Homo sapiens	133-159
2445500-6	1987	The permeabilized cells incorporated deoxyribonucleotides ([methyl -3H]-TTP) into DNA at a linear rate of 0.047 nmol per 10(7) cells min-1, representing 90-100 per cent of the DNA synthesis rate in vivo.	[methyl -3h]-ttp	59-75	CD59 molecule (CD59 blood group)	Homo sapiens	133-159
3321540-3	1987	Oral terbutaline improved morning peak flow (259 v 213 l min-1) and decreased nocturnal inhaler usage (1.3 v 1.9) with no alteration in sleep quality as assessed electroencephalographically.	Terbutaline	5-16	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
3678237-9	1987	In 3 patients with sinus rate less than 50 beats min-1 and an abnormal intrinsic heart rate, quinidine induced marked depression of sinus automaticity.	Quinidine	93-102	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
3661438-8	1987	The slope of labetalol concentration vs heart rate for elderly vs young patients was 0.176 +/- 0.063 vs 0.406 +/- 0.303 ng/ml X beats/min-1 (p less than 0.05), with 2 elderly patients showing no decrease in heart rate.	Labetalol	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
2820729-2	1987	The purification resulted in enzyme with a specific activity in excess of 1,000 nmol phosphate mg-1 min-1 in relatively high yield.	Phosphates	85-94	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
3631611-5	1987	There was a significant drop in maternal blood pressure when halothane was administered but uterine blood flow was maintained, 308 ml X min-1 during asphyxia versus 275 ml X min-1 with halothane.	Halothane	61-70	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
2822067-8	1987	4 Urinary analysis showed a significant decrease in renal clearance (CLR) with age for both pentopril (107 vs 203 ml min-1) and its active metabolite (116 vs 205 ml min-1).	CGS 13945	92-101	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
3446365-3	1987	When dobutamine was infused at 10 micrograms.kg-1.min-1 seven out of 10 patients had power output values above the defined limits, implying that the technique can identify correctly in vivo the direct positive inotropic effects of dobutamine in the presence of its vasodilating activity.	Dobutamine	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
3446365-3	1987	When dobutamine was infused at 10 micrograms.kg-1.min-1 seven out of 10 patients had power output values above the defined limits, implying that the technique can identify correctly in vivo the direct positive inotropic effects of dobutamine in the presence of its vasodilating activity.	Dobutamine	231-241	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
3659605-3	1987	When they propelled themselves under water for 33 sec by kicking their legs and breathed through a snorkel tube, heart rate increased progressively to a value of 118 +/- 4.1 beats X min-1 at 28 sec.	Water	37-42	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
3300293-5	1987	In 23 patients receiving CyA in whom the serum creatinine concentration was less than 2.0 mg/dL, the mean DTPA clearance was 49.5 +/- 2.83 mL/min/1.73 m2.	Cyclosporine	25-28	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
3300293-5	1987	In 23 patients receiving CyA in whom the serum creatinine concentration was less than 2.0 mg/dL, the mean DTPA clearance was 49.5 +/- 2.83 mL/min/1.73 m2.	Creatinine	47-57	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
3300293-5	1987	In 23 patients receiving CyA in whom the serum creatinine concentration was less than 2.0 mg/dL, the mean DTPA clearance was 49.5 +/- 2.83 mL/min/1.73 m2.	Pentetic Acid	106-110	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
3604896-5	1987	In individuals with pretreatment glomerular filtration rates less than or equal to 80 ml/min/1.73m2, diltiazem monotherapy showed both short-term and long-term improvement in glomerular filtration rate (62%) and effective renal plasma flow (34%).	Diltiazem	101-110	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
3328648-2	1987	As a group, patients with cardiomyopathy had considerably lower calcium uptake rates (3.3(0.6) nmol.mg-1.min-1 vs 6.5(0.5) nmol.mg-1.min-1, p less than 0.01).	Calcium	64-71	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
3311755-7	1987	In the first hour metoprolol produced a decrease in cardiac output (1.3 l min-1; P less than 0.001) due to a reduction in heart rate (15 min-1; P less than 0.001) and a decrease in left ventricular stroke work index (10.7 g m m-2; P less than 0.001) due to a reduction in mean arterial pressure (10 mmHg; P less than 0.001).	Metoprolol	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
3311755-7	1987	In the first hour metoprolol produced a decrease in cardiac output (1.3 l min-1; P less than 0.001) due to a reduction in heart rate (15 min-1; P less than 0.001) and a decrease in left ventricular stroke work index (10.7 g m m-2; P less than 0.001) due to a reduction in mean arterial pressure (10 mmHg; P less than 0.001).	Metoprolol	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
3598003-3	1987	The first 12 months of training resulted in a 44% increase in maximal oxygen consumption (VO2max) from 25.0 +/- 1.3 to 35.9 +/- 1.5 ml X kg-1 X min-1 (p less than 0.001).	Oxygen	70-76	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
3298305-4	1987	This study was undertaken to determine whether exogenous D,L-3-hydroxybutyric acid at two infusion rates (40 and 30 mumol kg-1 min-1) for 180 min altered renal plasma flow (RPF), GFR, and the excretion rate of total protein, beta 2-microglobulin, and albumin in 11 normal (N) subjects and 11 IDDM patients in whom euglycemia was achieved and maintained using the insulin-glucose clamp technique.	d,l-3-hydroxybutyric acid	57-82	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
3298305-6	1987	The 40 mumol kg-1 min-1 D,L-3-hydroxybutyric acid infusion increased RPF and GFR in both N and IDDM subjects.	,l-3-hydroxybutyric acid	25-49	CD59 molecule (CD59 blood group)	Homo sapiens	18-23
3298305-10	1987	The 30 mumol kg-1 min-1 D,L-3-hydroxybutyric acid infusion increased RPF and GFR to a somewhat lesser extent in both groups.	d,l-3-hydroxybutyric acid	24-49	CD59 molecule (CD59 blood group)	Homo sapiens	18-23
3298305-14	1987	D,L-3-Hydroxybutyrate sodium salt (30 mumol kg-1 min-1) also was infused in 5 of the 11 diabetic patients.	d,l-3-hydroxybutyrate sodium salt	0-33	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
3298305-16	1987	Both total protein and beta 2-microglobulin, but not albumin, excretion rates increased during D,L-3-hydroxybutyric acid (40 mumol kg-1 min-1) infusion in N and IDDM subjects.	d,l-3-hydroxybutyric acid	95-120	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
3657485-5	1987	Oxygen uptake for the individual exercises ranged from 1.52 l X min-1 (32.6% of TM max) for the behind-neck-press exercise to 2.43 l X min-1 (52.1% of TM max) for the squat exercise.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
3657485-5	1987	Oxygen uptake for the individual exercises ranged from 1.52 l X min-1 (32.6% of TM max) for the behind-neck-press exercise to 2.43 l X min-1 (52.1% of TM max) for the squat exercise.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
3113526-4	1987	Specific CO2 reactivity (the change in flow per torr change in CO2) was 8.16 +/- 0.69 ml min-1 torr-1 which was equivalent to 2.0 +/- 0.1 per cent of the flow at 40 torr per torr change in CO2 (percentage CO2 reactivity).	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	9-12	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
3113526-4	1987	Specific CO2 reactivity (the change in flow per torr change in CO2) was 8.16 +/- 0.69 ml min-1 torr-1 which was equivalent to 2.0 +/- 0.1 per cent of the flow at 40 torr per torr change in CO2 (percentage CO2 reactivity).	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	63-66	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
3113526-4	1987	Specific CO2 reactivity (the change in flow per torr change in CO2) was 8.16 +/- 0.69 ml min-1 torr-1 which was equivalent to 2.0 +/- 0.1 per cent of the flow at 40 torr per torr change in CO2 (percentage CO2 reactivity).	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	63-66	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
3113526-4	1987	Specific CO2 reactivity (the change in flow per torr change in CO2) was 8.16 +/- 0.69 ml min-1 torr-1 which was equivalent to 2.0 +/- 0.1 per cent of the flow at 40 torr per torr change in CO2 (percentage CO2 reactivity).	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	63-66	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
3115779-3	1987	Doses of 10, 20, 40 and 80 micrograms min-1 of GTN or placebo were infused during treadmill exercise until symptom limiting chest pain or greater than or equal to 3 mm ST segment depression occurred.	Nitroglycerin	47-50	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
3115779-7	1987	These results suggest that 20 micrograms min-1 may be the optimal dose of GTN to achieve significant antianginal effects as demonstrated by the improved exercise tolerance and reduction of myocardial ischaemia.	Nitroglycerin	74-77	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
3595078-5	1987	The maximal peak in TSH, occurring at 23.00 hours, was abolished by dopamine infused at a rate of 1 microgram min-1 kg-1, and was unaffected by the lower rate of dopamine infusion (0.1 microgram min-1 kg-1).	Dopamine	68-76	CD59 molecule (CD59 blood group)	Homo sapiens	110-120
3595078-5	1987	The maximal peak in TSH, occurring at 23.00 hours, was abolished by dopamine infused at a rate of 1 microgram min-1 kg-1, and was unaffected by the lower rate of dopamine infusion (0.1 microgram min-1 kg-1).	Dopamine	68-76	CD59 molecule (CD59 blood group)	Homo sapiens	195-205
3595078-7	1987	Low dose dopamine (0.1 microgram min-1 kg-1) had a slight but insignificant effect with decreased prolactin levels at the end of the infusion whereas the higher dopamine dose was associated with significantly lower prolactin levels during and throughout the infusion.	Dopamine	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	33-43
2821643-5	1987	The maximum changes after placebo and after nedocromil 2 mg and 4 mg were -44.7, -32.7, and -11.8 l min-1.	Nedocromil	44-54	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
2883008-3	1987	A rate of maximally 280 nmol ATP min-1 mg ATP synthase-1 was achieved with monomerized bacteriorhodopsin compared with a rate of up to 45 nmol ATP min-1 mg-1 found for proteoliposomes containing bacteriorhodopsin in the form of purple membrane patches.	Adenosine Triphosphate	42-45	CD59 molecule (CD59 blood group)	Homo sapiens	147-157
2436911-8	1987	It contains two steps with different responses from tryptophan (k3 approximately 0.77 min-1) and Chy-FITC (k3 approximately 0.19 min-1) fluorescence measurements.	chy-fitc	97-105	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
2883008-3	1987	A rate of maximally 280 nmol ATP min-1 mg ATP synthase-1 was achieved with monomerized bacteriorhodopsin compared with a rate of up to 45 nmol ATP min-1 mg-1 found for proteoliposomes containing bacteriorhodopsin in the form of purple membrane patches.	Adenosine Triphosphate	29-32	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
2883008-3	1987	A rate of maximally 280 nmol ATP min-1 mg ATP synthase-1 was achieved with monomerized bacteriorhodopsin compared with a rate of up to 45 nmol ATP min-1 mg-1 found for proteoliposomes containing bacteriorhodopsin in the form of purple membrane patches.	Adenosine Triphosphate	42-45	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
3578878-2	1987	Dopamine was infused at rates of 2, 4, and 8 micrograms X kg-1 X min-1.	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
3578878-4	1987	Before TEA, dopamine 8 micrograms X kg-1 X min-1 decreased systemic vascular resistance 4 +/- 4 mmHg min X 1-1 (m +/- SD) (P less than 0.05), but increased mean arterial pressure 15 +/- 12 mmHg (P less than 0.01), cardiac output 1.9 +/- 1.0 1 X min-1 (P less than 0.01), heart rate 10 +/- 9 beats X min-1 (P less than 0.05), and plasma norepinephrine concentration 544 +/- 252 pg X ml-1 (P less than 0.01).	Dopamine	12-20	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
3578878-4	1987	Before TEA, dopamine 8 micrograms X kg-1 X min-1 decreased systemic vascular resistance 4 +/- 4 mmHg min X 1-1 (m +/- SD) (P less than 0.05), but increased mean arterial pressure 15 +/- 12 mmHg (P less than 0.01), cardiac output 1.9 +/- 1.0 1 X min-1 (P less than 0.01), heart rate 10 +/- 9 beats X min-1 (P less than 0.05), and plasma norepinephrine concentration 544 +/- 252 pg X ml-1 (P less than 0.01).	Dopamine	12-20	CD59 molecule (CD59 blood group)	Homo sapiens	245-250
3578878-4	1987	Before TEA, dopamine 8 micrograms X kg-1 X min-1 decreased systemic vascular resistance 4 +/- 4 mmHg min X 1-1 (m +/- SD) (P less than 0.05), but increased mean arterial pressure 15 +/- 12 mmHg (P less than 0.01), cardiac output 1.9 +/- 1.0 1 X min-1 (P less than 0.01), heart rate 10 +/- 9 beats X min-1 (P less than 0.05), and plasma norepinephrine concentration 544 +/- 252 pg X ml-1 (P less than 0.01).	Dopamine	12-20	CD59 molecule (CD59 blood group)	Homo sapiens	245-250
3578878-6	1987	TEA reduced mean arterial pressure from 96 +/- 18 to 55 +/- 8 mmHg (P less than 0.01), cardiac output from 4.7 +/- 0.9 to 3.9 +/- 0.9 1 X min-1 (P = 0.05), systemic vascular resistance from 21 +/- 6 to 14 +/- 3 mmHg min X 1-1 (P less than 0.05), and plasma norepinephrine concentration from 394 +/- 141 to 207 +/- 73 pg X ml-1 (P less than 0.01).	tea	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
3105944-4	1987	Small doses of nitroprusside (1 to 2 micrograms/min) increased FBF in fingers vasoconstricted by intra-arterial norepinephrine (4.7 +/- SE 1.7 to 38.4 +/- 26 ml min-1 100 ml-1 of tissue).	Nitroprusside	15-28	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
3552793-6	1987	The basal glucose disposal rate was 86 +/- 2 mg X m-2 X min-1 and did not increase significantly during the clamp studies.	Glucose	10-17	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
3609048-6	1987	Calculations revealed that over 12 g of sotalol was absorbed into the circulation, while the half life was 9.2 h and the oral clearance 294 mg min-1.	Sotalol	40-47	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Diethyl Pyrocarbonate	103-123	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Diethyl Pyrocarbonate	103-123	CD59 molecule (CD59 blood group)	Homo sapiens	306-311
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Diethyl Pyrocarbonate	103-123	CD59 molecule (CD59 blood group)	Homo sapiens	306-311
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Histidine	245-254	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Histidine	245-254	CD59 molecule (CD59 blood group)	Homo sapiens	306-311
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Histidine	245-254	CD59 molecule (CD59 blood group)	Homo sapiens	306-311
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Histidine	355-364	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Histidine	355-364	CD59 molecule (CD59 blood group)	Homo sapiens	306-311
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Histidine	355-364	CD59 molecule (CD59 blood group)	Homo sapiens	306-311
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Histidine	355-364	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Histidine	355-364	CD59 molecule (CD59 blood group)	Homo sapiens	306-311
3657775-6	1987	The following values of kinetic parameters for the modification of pyruvate dehydrogenase component by diethylpyrocarbonate were obtained (pH 6.0; 20 degrees C): k1 = 6400 +/- 400 M-1 min-1 (the microscopic rate constant for the modification of histidine residue in the intact dimer), k2 = 890 +/- 200 M-1 min-1 (the rate constant for the modification of histidine residue in the intact subunit in the dimer which contains one modified subunit) and kt = 0.9 +/- 0.2 min-1 (the rate constant for conformational transition of the dimer induced by modification of histidine residue in one of the subunits in the dimeric molecule).	Histidine	355-364	CD59 molecule (CD59 blood group)	Homo sapiens	306-311
3116720-5	1987	At 4 degrees C, 2.2 pM labelled IL-2 (ala 125) bound to PHA-blasts (3.6 X 10(6)/ml) with a half time of about 15 min, and the association rate constant was approximately 8 X 10(9) M-1 min-1.	Alanine	38-41	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
3034033-2	1987	Norepinephrine was infused at doses of 0.1, 0.2 and 0.3 micrograms kg-1 min-1, each for 10 minutes, during control and 3 hours after ramipril administration.	Norepinephrine	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
3034033-4	1987	Ramipril significantly affected the baroreceptor set point with a decrease in mean blood pressure (72.1 +/- 1.7 vs 76.4 +/- 0.9 mm Hg, p less than 0.01) in the presence of unchanged heart rate (71.7 +/- 0.9 vs 73.6 +/- 1.5 min-1).	Ramipril	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	223-228
3591377-5	1987	infusion of bethanechol (10 nmol kg-1 min-1) acting directly on muscarinic receptors on smooth muscle.	Bethanechol	12-23	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
3591377-8	1987	Colonic contraction induced by PNS (P less than 0.01) was dose-dependently reduced by NPY (50-400 pmol min-1; P less than 0.05-0.01) and noradrenaline (1000-6000 pmol min-1; P less than 0.05-0.01).	Norepinephrine	137-150	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
3591377-8	1987	Colonic contraction induced by PNS (P less than 0.01) was dose-dependently reduced by NPY (50-400 pmol min-1; P less than 0.05-0.01) and noradrenaline (1000-6000 pmol min-1; P less than 0.05-0.01).	Norepinephrine	137-150	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
3591377-12	1987	Similarly, noradrenaline only at the highest dose (6000 pmol min-1) reduced the contractile response (P less than 0.01).	Norepinephrine	11-24	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
3592145-8	1987	Subcutaneously administered adrenaline caused within 5 min a significant increase of plasma adrenaline level (from 1.0 +/- 0.2 to peak of 6.5 +/- 1.2 nM) which gradually decreased during 2 h. This mode of adrenaline administration increased the systolic blood pressure by a maximum of 11 +/- 3.5 mmHg, heart rate by 9 +/- 2.2 beats X min-1, tremor ratio by 4 +/- 0.6 and reduced the diastolic blood pressure by 18 +/- 4.7 mmHg.	Epinephrine	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	334-339
3592145-8	1987	Subcutaneously administered adrenaline caused within 5 min a significant increase of plasma adrenaline level (from 1.0 +/- 0.2 to peak of 6.5 +/- 1.2 nM) which gradually decreased during 2 h. This mode of adrenaline administration increased the systolic blood pressure by a maximum of 11 +/- 3.5 mmHg, heart rate by 9 +/- 2.2 beats X min-1, tremor ratio by 4 +/- 0.6 and reduced the diastolic blood pressure by 18 +/- 4.7 mmHg.	Epinephrine	92-102	CD59 molecule (CD59 blood group)	Homo sapiens	334-339
3592145-8	1987	Subcutaneously administered adrenaline caused within 5 min a significant increase of plasma adrenaline level (from 1.0 +/- 0.2 to peak of 6.5 +/- 1.2 nM) which gradually decreased during 2 h. This mode of adrenaline administration increased the systolic blood pressure by a maximum of 11 +/- 3.5 mmHg, heart rate by 9 +/- 2.2 beats X min-1, tremor ratio by 4 +/- 0.6 and reduced the diastolic blood pressure by 18 +/- 4.7 mmHg.	Epinephrine	92-102	CD59 molecule (CD59 blood group)	Homo sapiens	334-339
3566386-4	1987	A progressive decline in ATP levels was observed during flow reduction with virtually complete depletion of ATP at 0.25 L min-1 m-2(p = .0003).	Adenosine Triphosphate	25-28	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
3566386-4	1987	A progressive decline in ATP levels was observed during flow reduction with virtually complete depletion of ATP at 0.25 L min-1 m-2(p = .0003).	Adenosine Triphosphate	108-111	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
3566386-6	1987	Lactate levels increased during flow reduction (p = .028), especially at flow rates less than 0.5 L min-1 m-2.	Lactic Acid	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
2883988-12	1987	After each dose, graded infusions of isoprenaline were given until the heart rate increased by 50 beats min-1.	Isoproterenol	37-49	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
2953384-3	1987	Diastolic blood pressure decreased significantly (P less than 0.05) at the higher dose (0.05 microgram kg-1 min-1) of alpha-hANP, which was attenuated by indomethacin pretreatment.	alpha-hanp	118-128	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
2953384-3	1987	Diastolic blood pressure decreased significantly (P less than 0.05) at the higher dose (0.05 microgram kg-1 min-1) of alpha-hANP, which was attenuated by indomethacin pretreatment.	Indomethacin	154-166	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
3102297-6	1987	After exercise, total glucose disposal was significantly increased during the 40-mU X m-2 X min-1 infusion (P less than .05), but the increase observed during the 400-mU X m-2 X min-1 infusion was not significant.	Glucose	22-29	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
3034621-4	1987	infusion of propranolol (1.0 microgram kg-1 min-1).	Propranolol	12-23	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
3582518-6	1987	Theophylline increased the hypokalaemia, tachycardia and rise in systolic blood pressure which occurs in response to intravenous infusion of doses of L-adrenaline (0.02-0.06 microgram kg-1 min-1).	Theophylline	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	189-194
3582518-6	1987	Theophylline increased the hypokalaemia, tachycardia and rise in systolic blood pressure which occurs in response to intravenous infusion of doses of L-adrenaline (0.02-0.06 microgram kg-1 min-1).	Epinephrine	150-162	CD59 molecule (CD59 blood group)	Homo sapiens	189-194
2435656-6	1987	The pulse rate did not change, but renal blood flow (p-aminohippurate clearance) increased (from 902 +/- 78 to 1108 +/- 130 ml/min/1.73 m2; p less than 0.05).	p-Aminohippuric Acid	53-69	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
3599639-1	1987	Continuous measurement of hemodynamic and gas exchange parameters during the administration of sodium nitroprusside (0.5-1 microgram/kg/min-1) in 25 patients with marked heart failure following mitral valve replacement demonstrated favorable hemodynamic and respiratory changes.	Nitroprusside	95-115	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
3554640-4	1987	Clearance studies 6 weeks after Tx exhibited significantly lower rates in the CsA group: Cin = 47 +/- 16.5 versus 83 +/- 25 ml/min/1.73 sqm, CPAH = 271 +/- 110 versus 503 +/- 181 ml/min/1.73 sqm (P less than 0.001).	Cyclosporine	78-81	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
3554640-4	1987	Clearance studies 6 weeks after Tx exhibited significantly lower rates in the CsA group: Cin = 47 +/- 16.5 versus 83 +/- 25 ml/min/1.73 sqm, CPAH = 271 +/- 110 versus 503 +/- 181 ml/min/1.73 sqm (P less than 0.001).	Cyclosporine	78-81	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
3577821-7	1987	Thus, adenosine 0.09 mg kg-1 min-1 was associated with an increase in heart rate (mean +/- SD) from baseline before saline with 16 +/- 10 b.p.m.	Adenosine	6-15	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
3577821-7	1987	Thus, adenosine 0.09 mg kg-1 min-1 was associated with an increase in heart rate (mean +/- SD) from baseline before saline with 16 +/- 10 b.p.m.	Sodium Chloride	116-122	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
3577821-12	1987	above baseline was obtained with 0.005 mg kg-1 min-1 of adenosine as compared with 0.08-0.09 mg kg-1 min-1 of adenosine following saline.	Adenosine	56-65	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
3577821-12	1987	above baseline was obtained with 0.005 mg kg-1 min-1 of adenosine as compared with 0.08-0.09 mg kg-1 min-1 of adenosine following saline.	Adenosine	110-119	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
3577821-12	1987	above baseline was obtained with 0.005 mg kg-1 min-1 of adenosine as compared with 0.08-0.09 mg kg-1 min-1 of adenosine following saline.	Sodium Chloride	130-136	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
3548440-6	1987	Adenosine, but not vehicle, significantly (P less than 0.01) increased leg blood flow (from 2.7 +/- 0.3 to 8.7 +/- 2.5 ml X 100 ml tissue-1 X min-1), heart rate (from 66 +/- 3 to 80 +/- 4 beats/min), and urinary epinephrine excretion (from 2.8 +/- 0.4 to 5.4 +/- 0.8 ng/mg creatinine).	Adenosine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
3826206-3	1987	When compared with results in the control group, maximal oxygen uptake (ml/kg1 X min1) decreased significantly in the oral contraceptive users during the 6-month period of observation.	Oxygen	57-63	CD59 molecule (CD59 blood group)	Homo sapiens	81-85
3103662-2	1987	Ventilation with an FGF of 70 ml kg-1 min-1 produced mean PaCO2 and PE" CO2 values of 6.48 +/- 1.15 kPa and 6.41 +/- 0.76 kPa, respectively.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	60-63	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
3103662-3	1987	Patients were thus hypercapnic, which contrasts with the normocapnia achieved using an FGF of 100 ml kg-1 min-1 via the ADE system (E mode) (PaCO2 5.07 +/- 0.7 kPa; PE" CO2 4.83 +/- 0.46 kPa) (mean values +/- SD).	Adenine	120-123	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
3567048-3	1987	The maximum dose rates received by all subjects were 8.5 mg min-1 for adenosine and 16.8 mg min-1 for inosine.	Inosine	102-109	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
3567048-4	1987	Adenosine infusion at rates of 6.1 mg min-1 and above caused a significant increase in minute ventilation, principally due to an increase in tidal volume, with an associated significant fall in end-tidal Pco2.	Adenosine	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
3567048-4	1987	Adenosine infusion at rates of 6.1 mg min-1 and above caused a significant increase in minute ventilation, principally due to an increase in tidal volume, with an associated significant fall in end-tidal Pco2.	pco2	204-208	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
3567048-7	1987	Infusion of inosine at dose rates up to 16.8 mg min-1 produced no pharmacological effects.	Inosine	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
3568462-6	1987	The glomerular filtration rate (inulin clearance) was 148-153 ml/min/1.73 m2 and the endogenous glucose clearance was 112-160 ml/min/1.73 m2 when blood glucose levels were 72-82 mg/dl.	Blood Glucose	146-159	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
2882987-4	1987	The mean thiobenzamide S-oxidase activities at pH 7.4 and 8.4 were 1.39 +/- 0.51 and 2.74 +/- 1.28 nmol mg-1 min-1, respectively.	thiobenzamide	9-22	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
3589216-1	1987	Twelve patients with severe heart failure were given amrinone by intravenous infusion in doses rising from 1 to 2, 3 and 4 mg X min-1, the interval between each dose being 30 min.	Amrinone	53-61	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
3589216-4	1987	When given at a rate of more than 2 mg X min-1, amrinone significantly improved cardiac function (p less than 0.001).	Amrinone	48-56	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
3589216-8	1987	Thus, intravenous amrinone proved effective in patients with severe heart failure, with maximal effects being obtained in doses of 3 mg X min-1.	Amrinone	18-26	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
3105577-2	1987	The initial rate of phosphorylation of these proteins in the presence of EGF was 5.2 and 3.5 nmol of phosphate min-1 (mg of receptor protein)-1, and this was approximately 10- and 6-fold higher than the basal rate, respectively.	Phosphates	101-110	CD59 molecule (CD59 blood group)	Homo sapiens	111-143
3545299-5	1987	With fMet-tRNA as the donor, this kcat of peptidyltransferase is 8.3 min-1 when the 0.5 M NH4Cl ribosomal wash is present, compared to 3.8 min-1 in its absence.	Ammonium Chloride	90-95	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
3545299-5	1987	With fMet-tRNA as the donor, this kcat of peptidyltransferase is 8.3 min-1 when the 0.5 M NH4Cl ribosomal wash is present, compared to 3.8 min-1 in its absence.	Ammonium Chloride	90-95	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
3545299-6	1987	The kcat of peptidyltransferase is 2.0 min-1 when Ac-Phe-tRNA replaces fMet-tRNA in the presence of the ribosomal wash and decreases to 0.8 min-1 in its absence.	Phenylalanine	53-56	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
3545299-6	1987	The kcat of peptidyltransferase is 2.0 min-1 when Ac-Phe-tRNA replaces fMet-tRNA in the presence of the ribosomal wash and decreases to 0.8 min-1 in its absence.	Phenylalanine	53-56	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
3552039-4	1987	Second-order rate constants are 2000-3000 M-1 min-1 for cis-diamminediaquoplatinum(II) and 280-400 M-1 min-1 for cis- and trans-diammineaquochloroplatinum(II), respectively.	cis-diamminediaquoplatinum	56-82	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
3552039-4	1987	Second-order rate constants are 2000-3000 M-1 min-1 for cis-diamminediaquoplatinum(II) and 280-400 M-1 min-1 for cis- and trans-diammineaquochloroplatinum(II), respectively.	cis-diamminediaquoplatinum	56-82	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
3552039-4	1987	Second-order rate constants are 2000-3000 M-1 min-1 for cis-diamminediaquoplatinum(II) and 280-400 M-1 min-1 for cis- and trans-diammineaquochloroplatinum(II), respectively.	cis- and trans-diammineaquochloroplatinum	113-154	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
3552039-4	1987	Second-order rate constants are 2000-3000 M-1 min-1 for cis-diamminediaquoplatinum(II) and 280-400 M-1 min-1 for cis- and trans-diammineaquochloroplatinum(II), respectively.	cis- and trans-diammineaquochloroplatinum	113-154	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
3552039-7	1987	The biomolecular reaction is followed by a rearrangement (rate constant 0.22 min-1) that gives rise to most of the decrease in the fluorescence intensity and that depends on the state of aquation of the DNA-bound platinum(II) complex.	platinum(ii)	213-225	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
3104222-5	1987	3-AB added 2 h prior to and removed 18 h after irradiation at a non-toxic dose to unirradiated cells caused a small but consistent increase in cell kill with acute (150 cGy min-1) irradiation, largely involving a reduction in the shoulder region of the survival curve, but had a greater effect in increasing cell kill at a dose rate of 7.6 cGy min-1 and an even greater effect at a dose rate of 1.6 cGy min-1.	3-aminobenzamide	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
2440682-3	1987	The dose of Iloprost was 1-4 ng kg-1 min-1 and titrated according to blood pressure and systemic vascular resistance.	Iloprost	12-20	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
2440682-4	1987	When 2.0-4.0 ng kg-1 min-1 of Iloprost were infused, 5 out of 10 patients required dose reduction due to hypotension, nausea or both.	Iloprost	30-38	CD59 molecule (CD59 blood group)	Homo sapiens	21-26
2884060-6	1987	min-1 in A and B and 4 other MODs on sulphonylurea or diet therapy.	Sulfonylurea Compounds	37-50	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
3104222-5	1987	3-AB added 2 h prior to and removed 18 h after irradiation at a non-toxic dose to unirradiated cells caused a small but consistent increase in cell kill with acute (150 cGy min-1) irradiation, largely involving a reduction in the shoulder region of the survival curve, but had a greater effect in increasing cell kill at a dose rate of 7.6 cGy min-1 and an even greater effect at a dose rate of 1.6 cGy min-1.	3-aminobenzamide	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	344-349
3104222-5	1987	3-AB added 2 h prior to and removed 18 h after irradiation at a non-toxic dose to unirradiated cells caused a small but consistent increase in cell kill with acute (150 cGy min-1) irradiation, largely involving a reduction in the shoulder region of the survival curve, but had a greater effect in increasing cell kill at a dose rate of 7.6 cGy min-1 and an even greater effect at a dose rate of 1.6 cGy min-1.	3-aminobenzamide	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	344-349
3481210-7	1987	The Ki value for the tissue kallikrein aprotinin complex was measured as well as the bimolecular velocity constant for the inhibition by diisopropyl fluorophosphate was determined as 9 +/- 2 1 x mol-1 x min-1).	Isoflurophate	137-164	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
3578941-6	1987	The treatment included early gastric lavage, alkalinization, blocking of the metabolism of methanol by ethanol and haemodialysis with a bicarbonate dialysate enriched in ethanol; this corrected the acidosis and permitted the elimination of the toxic metabolites (clearance of methanol: 159 ml X min-1; half-life of methanol during purification: 3.46 +/- 1.32 h; quantity extracted: 246 g).	Bicarbonates	136-147	CD59 molecule (CD59 blood group)	Homo sapiens	295-300
3788870-6	1987	The effects of calcitriol on renal function were tested by creatinine clearance values, which were 127 +/- 22 mL/min/1.73 m2 (2.12 +/- 0.37 mL/s/1.73 m2) at the conclusion of the study, compared with 128 +/- 25 mL/min/1.73 m2 (2.13 +/- 0.41 mL/s/1.73 m2) obtained at the initiation of calcitriol therapy.	Creatinine	59-69	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
3578945-1	1987	An elderly patient, receiving long-term oral diltiazem at the usual dosage, presented a sudden attack of junctional bradycardia at 35 b X min-1; this was badly tolerated by the patient.	Diltiazem	45-54	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
3435503-6	1987	Highly purified sarcolemmal membranes, exhibiting an NaF-stimulated activity of 3.46 +/- 0.65 nmol cAMP formed min-1 mg-1 of protein, were exposed to free radicals formation of which was induced by Fe++/ascorbate.	Cyclic AMP	99-103	CD59 molecule (CD59 blood group)	Homo sapiens	111-121
3435503-6	1987	Highly purified sarcolemmal membranes, exhibiting an NaF-stimulated activity of 3.46 +/- 0.65 nmol cAMP formed min-1 mg-1 of protein, were exposed to free radicals formation of which was induced by Fe++/ascorbate.	Iron	198-202	CD59 molecule (CD59 blood group)	Homo sapiens	111-121
2880663-5	1987	In the 12 patients randomized to propranolol, heart rate, systolic and diastolic pressures, double product were significantly reduced at rest, compared with control exercise: 67 +/- 8 versus 81 +/- 10 beats/min (p less than 0.01), 132 +/- 20 versus 146 +/- 21 mm Hg (p less than 0.02), 80 +/- 8 versus 88 +/- 10 mm Hg (p less than 0.02), 8,828 +/- 1,927 versus 11,863 +/- 2,138 mm Hg X min-1 (p less than 0.001), respectively.	Propranolol	33-44	CD59 molecule (CD59 blood group)	Homo sapiens	386-391
3026718-2	1987	In vivo, blood pressure, heart rate, plasma noradrenaline and plasma cyclic AMP responses to isoprenaline (0.01, 0.02 and 0.05 microgram min-1 kg-1 intravenously) were related to the plasma concentrations of isoprenaline.	Isoproterenol	93-105	CD59 molecule (CD59 blood group)	Homo sapiens	137-147
3311362-3	1987	Stimulated prostacyclin production was not reduced by storage of vein for 2 h at 23 degrees C in blood or saline nor by distension, but it was reduced to 5.0(0.6) pg.min-1 per mg (n = 10) by de-endothelialisation.	Epoprostenol	11-23	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
3026718-2	1987	In vivo, blood pressure, heart rate, plasma noradrenaline and plasma cyclic AMP responses to isoprenaline (0.01, 0.02 and 0.05 microgram min-1 kg-1 intravenously) were related to the plasma concentrations of isoprenaline.	Isoproterenol	208-220	CD59 molecule (CD59 blood group)	Homo sapiens	137-147
2878848-5	1987	Glucose disposal rates between 120 and 180 min of the clamp were 7.11 +/- 0.10 and 7.35 +/- 0.10 mg X kg-1 X min-1 with and without SRIF, respectively (difference not significant).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
2888649-3	1987	We observed no significant difference (p greater than 0.1) between the heat tolerant (0.9 +/- 0.68 microgram) and heat intolerant (1.19 +/- 0.61 microgram) subjects in the dose of isoproterenol that produced a 25 beat.min-1 increment in heart rate.	Isoproterenol	180-193	CD59 molecule (CD59 blood group)	Homo sapiens	218-223
3653228-15	1987	group had urine output during the study period with renal ranitidine clearance values of 9.9 +/- 9.9 ml X min-1.	Ranitidine	58-68	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
3126051-1	1987	The administration of alfentanil by infusion appears to present advantages for the induction and maintenance of anaesthesia during general surgery lasting over 1 h. The following dosage scheme is proposed: a loading dose of 100 micrograms kg-1, given either in one or two doses, or as a fast infusion administered over 10 min, followed by a maintenance infusion at a rate of 1 microgram kg-1 min-1.	Alfentanil	22-32	CD59 molecule (CD59 blood group)	Homo sapiens	392-397
3126053-10	1987	This study supports the view that after an appropriate loading dose a fixed-rate infusion of alfentanil at 1 microgram kg-1 min-1 can be given for up to 7 h to provide satisfactory stable analgesia without undue post-operative ventilatory depression or prolonged recovery in the majority of cases.	Alfentanil	93-103	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
3126054-3	1987	Anaesthesia was induced with thiopentone, vecuronium and an anfentanil loading dose delivered by the infusion pump at a rate of 10 micrograms kg-1 min-1 for 10 min.	anfentanil	60-70	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
3126054-5	1987	After 10 min the maintenance infusion rate of alfentanil of 1 microgram kg-1 min-1 was begun.	Alfentanil	46-56	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
3126054-14	1987	The use of a 10-min, 10 micrograms kg-1 min-1 loading infusion, then a maintenance infusion of 1 microgram kg-1 min-1 delivered by a modified Fresenius-injectomat infusion pump may be the first step in simplifying the continuous infusion of alfentanil.	Alfentanil	241-251	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
3830244-7	1987	Ciprofloxacin was partly removed by haemodialysis (IIIb): the dialyser extraction ratio was 23% and the dialysis clearance was 40 ml X min-1.	Ciprofloxacin	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
2891535-14	1987	The optimal plasma concentration of thiazinamium was about 100 ng.ml-1, which should give a near maximal bronchodilator response (over 80% of predicted normal) and a heart rate of about 100 beats.min-1.	thiazinamium	36-48	CD59 molecule (CD59 blood group)	Homo sapiens	196-201
3691614-1	1987	Methohexitone was administered to 8 healthy adult volunteers as a microprocessor controlled infusion that generated 3 cycles of linearly increasing plasma levels with an anticipated slope of 0.2 microgram.ml-1.min-1.	Methohexital	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	210-215
3653161-2	1987	Although in 14 cases of the preoperative 131I-Hippuran clearance of the affected unit was less than 100 ml/min/1.25 m2, in 10 cases renal function was stabilized or slightly improved postoperatively.	131i-hippuran	41-54	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
3308487-11	1987	The oral plasma clearance of moracizine was relatively large (2.2 l X min-1), suggesting first-pass metabolism.	Moricizine	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
3316041-4	1987	Catecholamine excretion in urine (adrenaline + noradrenaline) on average was 252.3 +/- 77.9 ng min-1 during car racing and 121.9 +/- 37.3 ng min-1 during exhaustive ergometry (n = 10).	Catecholamines	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
3316041-4	1987	Catecholamine excretion in urine (adrenaline + noradrenaline) on average was 252.3 +/- 77.9 ng min-1 during car racing and 121.9 +/- 37.3 ng min-1 during exhaustive ergometry (n = 10).	Epinephrine	34-44	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
3316041-4	1987	Catecholamine excretion in urine (adrenaline + noradrenaline) on average was 252.3 +/- 77.9 ng min-1 during car racing and 121.9 +/- 37.3 ng min-1 during exhaustive ergometry (n = 10).	Norepinephrine	47-60	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
3557797-1	1987	Constant decay of polycyclic aromatic hydrocarbons (PAHs) adsorbed onto airborne particulate collected in glass fibre filters and exposed to sunlight ranged from 1.8 to 4.4 X 10(-3) (min-1), corresponding respectively to a half-life of 100 and 425 min.	Polycyclic Aromatic Hydrocarbons	18-50	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
3557797-1	1987	Constant decay of polycyclic aromatic hydrocarbons (PAHs) adsorbed onto airborne particulate collected in glass fibre filters and exposed to sunlight ranged from 1.8 to 4.4 X 10(-3) (min-1), corresponding respectively to a half-life of 100 and 425 min.	Polycyclic Aromatic Hydrocarbons	52-56	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
3668074-5	1987	Glucose oxidation rate (4.35 mg kg-1 min-1) exceeded glucose intake (2.6 mg kg-1 min-1).	Glucose	53-60	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
3693807-5	1987	We found that the acute decrease in intra-ocular pressure was equal to 1.39 +/- 0.44 microliter.min-1 for the Timolol treated eyes, and equal to 2.79 +/- 0.57 microliter.min-1 for the untreated eyes (Placebo).	Timolol	110-117	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
3306417-4	1987	In the patients with renal failure unrelated to primary hyperoxaluria, oxalate retention increases rapidly when the glomerular filtration rate (GFR) decreases below about 20 ml X min-1.	Oxalates	71-78	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
3787262-2	1986	MOPC167 catalysis displayed saturation kinetics with catalytic constant (kcat) = 0.4 min-1 and Michaelis constant (Km) = 208 microM, showed substrate specificity, and was inhibited by p-nitrophenylphosphorylcholine.	O-(4-Nitrophenylphosphoryl)choline	184-214	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	6-thiocyanatoflavins	0-20	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	6-thiocyanatoflavins	0-20	CD59 molecule (CD59 blood group)	Homo sapiens	269-274
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	Sulfites	99-106	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	Sulfites	99-106	CD59 molecule (CD59 blood group)	Homo sapiens	269-274
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	Sulfhydryl Compounds	111-117	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	Sulfhydryl Compounds	111-117	CD59 molecule (CD59 blood group)	Homo sapiens	269-274
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	6-s-so3--flavin	145-160	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	6-s-so3--flavin	145-160	CD59 molecule (CD59 blood group)	Homo sapiens	269-274
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	6-mercaptoflavin	165-181	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	6-mercaptoflavin	165-181	CD59 molecule (CD59 blood group)	Homo sapiens	269-274
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	Sulfites	248-255	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	Sulfites	248-255	CD59 molecule (CD59 blood group)	Homo sapiens	269-274
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	Dithiothreitol	279-293	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
2879564-1	1986	6-Thiocyanatoflavins have been found to be susceptible to nucleophilic displacement reactions with sulfite and thiols, yielding respectively the 6-S-SO3--flavin and 6-mercaptoflavin, with rate constants at pH 7.0, 20 degrees C, of 55 M-1 min-1 for sulfite and 1000 M-1 min-1 for dithiothreitol.	Dithiothreitol	279-293	CD59 molecule (CD59 blood group)	Homo sapiens	269-274
3538898-9	1986	The amount of exogenous glucose required to maintain euglycemia averaged 7.4 +/- 0.5 mg X kg-1 X min-1.	Glucose	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
3105568-6	1986	Lignocaine decreased cardiac index (-0.3 l min-1 m-2 (9%); P less than 0.05) and stroke volume index (-5 ml m-2 (11%); P less than 0.01).	Lidocaine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
2881786-1	1986	The effects of direct adrenergic stimulation, achieved by 60-min adrenaline infusion (0.1-0.2 microgram kg-1 min-1), on thromboxane B2 (TxB2) production by platelets in whole blood ex vivo and on ADP-induced platelet aggregation were studied in seven healthy male volunteers.	Epinephrine	65-75	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
3100495-4	1986	Comparisons were made between control experiments and experiments with a 3-micrograms X kg-1 X min-1 intravenous infusion of dopamine.	Dopamine	125-133	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
3784914-5	1986	The maximum uricosuric response promoted by probenecid at high serum urate levels was (mean +/- SD) 3,707 +/- 443 micrograms/min/1.73 m2 in controls and 2,215 +/- 738 micrograms/min/1.73 m2 in patients with gout (P less than 0.01).	Probenecid	44-54	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
3784914-5	1986	The maximum uricosuric response promoted by probenecid at high serum urate levels was (mean +/- SD) 3,707 +/- 443 micrograms/min/1.73 m2 in controls and 2,215 +/- 738 micrograms/min/1.73 m2 in patients with gout (P less than 0.01).	Probenecid	44-54	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
3784914-5	1986	The maximum uricosuric response promoted by probenecid at high serum urate levels was (mean +/- SD) 3,707 +/- 443 micrograms/min/1.73 m2 in controls and 2,215 +/- 738 micrograms/min/1.73 m2 in patients with gout (P less than 0.01).	Uric Acid	69-74	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
3784914-7	1986	When serum urate was reduced in normal subjects and 30 patients to a mean of 2.1 and 2.3 mg/dL, respectively, probenecid elicited a significantly lower urate excretion rate in gout (532 +/- 202 micrograms/min/1.73 m2) than in controls (922 +/- 136 micrograms/min/1.73 m2; P less than 0.01).	Probenecid	110-120	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
3784914-7	1986	When serum urate was reduced in normal subjects and 30 patients to a mean of 2.1 and 2.3 mg/dL, respectively, probenecid elicited a significantly lower urate excretion rate in gout (532 +/- 202 micrograms/min/1.73 m2) than in controls (922 +/- 136 micrograms/min/1.73 m2; P less than 0.01).	Probenecid	110-120	CD59 molecule (CD59 blood group)	Homo sapiens	259-264
2432930-2	1986	The individual, homogeneous class I isozymes oxidize (3,4-dihydroxyphenyl)ethanol and (4-hydroxy-3-methoxyphenyl)ethanol (HMPE) and ethanol with kcat/Km values in the range from 16 to 240 mM-1 min-1 and from 16 to 66 mM-1 min-1, respectively.	3,4-dihydroxyphenylethanol	53-81	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
2432930-2	1986	The individual, homogeneous class I isozymes oxidize (3,4-dihydroxyphenyl)ethanol and (4-hydroxy-3-methoxyphenyl)ethanol (HMPE) and ethanol with kcat/Km values in the range from 16 to 240 mM-1 min-1 and from 16 to 66 mM-1 min-1, respectively.	3,4-dihydroxyphenylethanol	53-81	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
2432930-2	1986	The individual, homogeneous class I isozymes oxidize (3,4-dihydroxyphenyl)ethanol and (4-hydroxy-3-methoxyphenyl)ethanol (HMPE) and ethanol with kcat/Km values in the range from 16 to 240 mM-1 min-1 and from 16 to 66 mM-1 min-1, respectively.	3-Methoxy-4-hydroxyphenylethanol	86-120	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
2432930-2	1986	The individual, homogeneous class I isozymes oxidize (3,4-dihydroxyphenyl)ethanol and (4-hydroxy-3-methoxyphenyl)ethanol (HMPE) and ethanol with kcat/Km values in the range from 16 to 240 mM-1 min-1 and from 16 to 66 mM-1 min-1, respectively.	3-Methoxy-4-hydroxyphenylethanol	86-120	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
2432930-2	1986	The individual, homogeneous class I isozymes oxidize (3,4-dihydroxyphenyl)ethanol and (4-hydroxy-3-methoxyphenyl)ethanol (HMPE) and ethanol with kcat/Km values in the range from 16 to 240 mM-1 min-1 and from 16 to 66 mM-1 min-1, respectively.	Ethanol	74-81	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
2432930-2	1986	The individual, homogeneous class I isozymes oxidize (3,4-dihydroxyphenyl)ethanol and (4-hydroxy-3-methoxyphenyl)ethanol (HMPE) and ethanol with kcat/Km values in the range from 16 to 240 mM-1 min-1 and from 16 to 66 mM-1 min-1, respectively.	Ethanol	74-81	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
3778789-4	1986	In infants the clearance of atracurium in ml m-2 min-1 (153 v. 133) tended to be greater and the T1/2 alpha and T1/2 beta tended to be shorter (1.0 v. 2.0 and 13.6 v. 19.1) than in children with normal excretory function; however, these trends did not reach statistical significance.	Atracurium	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
3778794-5	1986	Total serum clearance of galanthamine amounted to 5.37 +/- 0.87 ml min-1 kg-1, and the renal clearance was 1.36 +/- 0.10 ml min-1 kg-1.	Galantamine	25-37	CD59 molecule (CD59 blood group)	Homo sapiens	67-77
3790406-6	1986	Renal clearance of salbutamol was 291 +/- 70 ml min-1 after intravenous and 272 +/- 38 ml min-1 after oral administration, while the renal clearance of the sulphate conjugate was 98.5 +/- 23.5 ml min-1 after oral administration.	Albuterol	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
3790406-6	1986	Renal clearance of salbutamol was 291 +/- 70 ml min-1 after intravenous and 272 +/- 38 ml min-1 after oral administration, while the renal clearance of the sulphate conjugate was 98.5 +/- 23.5 ml min-1 after oral administration.	Albuterol	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
3790406-6	1986	Renal clearance of salbutamol was 291 +/- 70 ml min-1 after intravenous and 272 +/- 38 ml min-1 after oral administration, while the renal clearance of the sulphate conjugate was 98.5 +/- 23.5 ml min-1 after oral administration.	Albuterol	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
3769385-4	1986	For desipramine the apparent oral clearance (L X min-1) was 0.19 (0.12 to 0.24) in PM compared with 1.64 (1.46 to 1.80) and 1.03 (0.77 to 1.13) in rapid EM and slow EM.	Desipramine	4-15	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
3539618-12	1986	The overall haemodynamic response to metoprolol was similar to that reported in patients with acute myocardial infarction and heart rate above 65 beats min-1.	Metoprolol	37-47	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
3803759-4	1986	At pH 7.40 and 25 degrees C the dissociation constant Kd of this complex and the rate constant k2 of cleavage of soman by beta-cyclodextrin are (0.53 +/- 0.05) mM and (5.9 +/- 0.6) X 10(-2) min-1, respectively.	betadex	122-139	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
3803759-5	1986	The rate constant k2 max for the cleavage of soman by monoionized beta-cyclodextrin has a value of 2.8 X 10(3) min-1 and the second order rate constant k2 max/kd is 5.3 X 10(6) M-1 min-1.	betadex	66-83	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
3803759-5	1986	The rate constant k2 max for the cleavage of soman by monoionized beta-cyclodextrin has a value of 2.8 X 10(3) min-1 and the second order rate constant k2 max/kd is 5.3 X 10(6) M-1 min-1.	betadex	66-83	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
3612569-2	1986	Ambient air passed through the segment at 11 min-1 increased the output of both 35S- and 3H-labelled mucins.	Sulfur-35	80-83	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
3612569-2	1986	Ambient air passed through the segment at 11 min-1 increased the output of both 35S- and 3H-labelled mucins.	Tritium	89-91	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
2432675-3	1986	The maximum second order rate constant of heparin cofactor II-thrombin reaction in the presence of the fractions of over-10 kDa and 18% sulfur was 2.7 X 10(8) M-1 min-1 that was almost same as in the presence of heparin or dermatan sulfate.	Heparin	42-49	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
2432675-3	1986	The maximum second order rate constant of heparin cofactor II-thrombin reaction in the presence of the fractions of over-10 kDa and 18% sulfur was 2.7 X 10(8) M-1 min-1 that was almost same as in the presence of heparin or dermatan sulfate.	Sulfur	136-142	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
2432675-3	1986	The maximum second order rate constant of heparin cofactor II-thrombin reaction in the presence of the fractions of over-10 kDa and 18% sulfur was 2.7 X 10(8) M-1 min-1 that was almost same as in the presence of heparin or dermatan sulfate.	Heparin	212-219	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
2432675-3	1986	The maximum second order rate constant of heparin cofactor II-thrombin reaction in the presence of the fractions of over-10 kDa and 18% sulfur was 2.7 X 10(8) M-1 min-1 that was almost same as in the presence of heparin or dermatan sulfate.	Dermatan Sulfate	223-239	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
3489314-4	1986	We found that in pulse (15 min-2 hr)-chase (0-4 hr) experiments the cleavage of not only Pr65gag to p30 and other gag coded proteins but Pr80env to gp70 and Pr15(E) as well, was greatly reduced by cerulenin treatment.	Cerulenin	197-206	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
3790498-4	1986	When both factor Va and phospholipid were present during prothrombin activation, factor Xa inhibition by antithrombin III was reduced about 10-fold, with a second-order rate constant of 1.3 X 10(5) M-1 min-1.	Phospholipids	24-36	CD59 molecule (CD59 blood group)	Homo sapiens	202-207
3790498-6	1986	The first-order rate constants of these reactions at 200 nM antithrombin III and normalized to heparin at 1 microgram/mL were 0.33 and 9.5 min-1 in the presence and absence of factor Va and phospholipid, respectively.	Heparin	95-102	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
2875678-2	1986	Alfentanil was administered as a loading infusion (25-130 micrograms/kg) followed by a maintenance infusion (0.25-1.3 micrograms X kg-1 X min-1) as part of a nitrous oxide-narcotic-muscle relaxant technique.	Alfentanil	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
2875678-4	1986	The alfentanil clearance rate was significantly lower in patients with liver dysfunction (2.3 +/- 1.3 vs 4.2 +/- 2.0 ml X kg-1 X min-1, mean +/- SD).	Alfentanil	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
2875679-1	1986	In a group of seven patients undergoing intracranial surgery under neurolept anesthesia, an alfentanil infusion was initiated with a loading dose of 235 micrograms/kg over 5 min, followed by a maintenance infusion rate of 1.8 microgram X kg-1 X min-1 in order to obtain a steady state plasma concentration (Css) of 400 ng/ml-1 according to an infusion model.	Alfentanil	92-102	CD59 molecule (CD59 blood group)	Homo sapiens	245-250
2876719-6	1986	The required infusion rate for alfentanil was between 0.4 and 0.5 micrograms kg-1 min-1.	Alfentanil	31-41	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
2876720-3	1986	Requirements for vecuronium averaged 1.1 micrograms kg-1 min-1 (0.8-1.5 micrograms kg-1 min-1), being in the same range as for repeated bolus injections.	Vecuronium Bromide	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
2876720-3	1986	Requirements for vecuronium averaged 1.1 micrograms kg-1 min-1 (0.8-1.5 micrograms kg-1 min-1), being in the same range as for repeated bolus injections.	Vecuronium Bromide	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
3533120-4	1986	The duration of the midazolam infusion (2-6 micrograms kg-1 min-1) ranged from 12 to 197 h. Forty-seven of the children were sedated uneventfully; the remaining three children needed small doses of other sedative agents.	Midazolam	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
3019586-4	1986	In contrast, although similar with respect to all pretreatment demographic, hemodynamic, and clinical variables, patients with a creatinine clearance under 50 ml/min/1.73 m2 had low values for plasma renin activity (3.4 +/- 0.8 ng/ml/hr) and, despite similar drug-induced decreases in systemic blood pressure, showed no change in creatinine clearance after therapy with captopril or enalapril (32.6 +/- 2.5 to 41.4 +/- 3.8 ml/min/1.73 m2).	Creatinine	129-139	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
3019586-4	1986	In contrast, although similar with respect to all pretreatment demographic, hemodynamic, and clinical variables, patients with a creatinine clearance under 50 ml/min/1.73 m2 had low values for plasma renin activity (3.4 +/- 0.8 ng/ml/hr) and, despite similar drug-induced decreases in systemic blood pressure, showed no change in creatinine clearance after therapy with captopril or enalapril (32.6 +/- 2.5 to 41.4 +/- 3.8 ml/min/1.73 m2).	Creatinine	129-139	CD59 molecule (CD59 blood group)	Homo sapiens	426-431
3100310-6	1986	Estimated whole-body clearance of noradrenaline was mean 0.80 l min-1 X M-2 (n = 6) while the pulmonary clearance amounted to 19% of this value.	Norepinephrine	34-47	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
3586103-5	1986	Maximum oxygen uptake was increased by 18% post-training (3.29 +/- 0.29 1 min-1 versus 3.89 +/- 0.49 1 min-1; P less than 0.01), but endurance at the same absolute work rate as pre-training was increased by more than 200% (32.2 +/- 11.4 min versus 97.8 +/- 27.3 min; P less than 0.01).	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
3586103-5	1986	Maximum oxygen uptake was increased by 18% post-training (3.29 +/- 0.29 1 min-1 versus 3.89 +/- 0.49 1 min-1; P less than 0.01), but endurance at the same absolute work rate as pre-training was increased by more than 200% (32.2 +/- 11.4 min versus 97.8 +/- 27.3 min; P less than 0.01).	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
3489478-2	1986	Measurements were performed with the patient awake, during steady-state maintenance anaesthesia with propofol 200 micrograms kg-1 min-1 at rest, and during sternotomy when the propofol was supplemented with fentanyl 10 micrograms kg-1.	Propofol	101-109	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
2876780-2	1986	Two of the three bands that are precipitated from metabolically labeled cells are expressed on the cell surface and can be recovered from the supernatants of cells treated with a phosphatidylinositol-specific phospholipase C. Thus TAP appears to be attached to the cell membrane via this lipid.	Phosphatidylinositols	179-199	CD59 molecule (CD59 blood group)	Homo sapiens	231-234
2875724-3	1986	The plasma clearance of vecuronium was decreased significantly (P less than 0.01) from 4.30 +/- 1.56 ml min-1 kg-1 (mean +/- SD) in normal patients to 2.36 +/- 0.80 ml min-1 kg-1 in patients with cholestasis.	Vecuronium Bromide	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	104-114
2875724-3	1986	The plasma clearance of vecuronium was decreased significantly (P less than 0.01) from 4.30 +/- 1.56 ml min-1 kg-1 (mean +/- SD) in normal patients to 2.36 +/- 0.80 ml min-1 kg-1 in patients with cholestasis.	Vecuronium Bromide	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	168-178
3527829-3	1986	The individual fasting glucose levels were highly correlated with the elevated basal rates of hepatic glucose output (HGO) (r = 0.91, P less than .001), which fell from 138 +/- 11 to 87 +/- 5 mg X m-2 X min-1 after weight loss.	Glucose	23-30	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
2429087-2	1986	The first dose of nicardipine produced an increase in renal blood flow (from 888 +/- 45 to 999 +/- 59 ml/min 1.73 m2, p less than 0.01) and a decrease in renal vascular resistances (from 0.16 +/- 0.01 to 0.12 +/- 0.01 arbitrary unit, p less than 0.05).	Nicardipine	18-29	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
3490273-2	1986	This compound, dansyl-Glu-Gly-Arg chloromethyl ketone (DEGER), inhibits porcine factor IXa with a second-order rate constant of 2.2 X 10(4) M-1 min-1.	dansylglutamyl-glycyl-arginine chloromethyl ketone	15-53	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
3526984-9	1986	Infusion of esmolol at 200 micrograms X kg-1 X min-1 prevented tachycardia in response to intubation.	esmolol	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
3753359-7	1986	When Qsb was corrected (Qsb) by a linear regression based on the difference between Re and Rsb during exercise and by adding 2.44 L X min-1 at rest (the mean difference), the relationship was greatly improved (Qsb = 0.14 + 0.99 Qf, r = +0.93, mean difference +/- S.D.	3-Bromo-4-hydroxybenzoic acid	5-8	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
3753359-7	1986	When Qsb was corrected (Qsb) by a linear regression based on the difference between Re and Rsb during exercise and by adding 2.44 L X min-1 at rest (the mean difference), the relationship was greatly improved (Qsb = 0.14 + 0.99 Qf, r = +0.93, mean difference +/- S.D.	3-Bromo-4-hydroxybenzoic acid	24-27	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
3753359-7	1986	When Qsb was corrected (Qsb) by a linear regression based on the difference between Re and Rsb during exercise and by adding 2.44 L X min-1 at rest (the mean difference), the relationship was greatly improved (Qsb = 0.14 + 0.99 Qf, r = +0.93, mean difference +/- S.D.	3-Bromo-4-hydroxybenzoic acid	24-27	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
3756064-4	1986	All three drugs caused a tachycardia, mean increase in the pulse being 16, 8 and 2 beats min-1 for salbutamol, aminophylline and VIP respectively, and aminophylline also increased both systolic and diastolic blood pressure, mean arterial pressure increasing by 14 mmHg.	Albuterol	99-109	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
3756064-4	1986	All three drugs caused a tachycardia, mean increase in the pulse being 16, 8 and 2 beats min-1 for salbutamol, aminophylline and VIP respectively, and aminophylline also increased both systolic and diastolic blood pressure, mean arterial pressure increasing by 14 mmHg.	Aminophylline	111-124	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
3769414-4	1986	The resistance of the valve to a flow of air at a rate of 20 l min-1 is 2.2 mm of water at the inlet and 4.2 mm of water at the outlet.	Water	82-87	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
3769414-4	1986	The resistance of the valve to a flow of air at a rate of 20 l min-1 is 2.2 mm of water at the inlet and 4.2 mm of water at the outlet.	Water	115-120	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
3769414-5	1986	At a rate of flow of 100 l min-1 the corresponding figures are 8.9 and 24.6 mm of water.	Water	82-87	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
3756133-7	1986	However, kinetic constants revealed that the Km value of protein kinase C activated by SC-9 for substrate myosin light chain was 5.8 microM, that is, about 10 times lower than that of the enzyme with phosphatidylserine, and that the Vmax value with SC-9 was 0.13 nmol X min-1, that is, 3-fold smaller than that seen with phosphatidylserine.	N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide	87-91	CD59 molecule (CD59 blood group)	Homo sapiens	270-275
3740056-4	1986	The results demonstrate that net potassium secretion was increased in subjects with renal failure (-5.2 +/- 0.9 microEq X min-1) compared with the control value of -2.0 +/- 0.4 microEq (P less than .05).	Potassium	33-42	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
2943308-1	1986	Intravenous administration of amlodipine (single dose, 10 mg) to 12 volunteers gave a mean plasma half-life of 34 h, mean clearance of 7 ml min-1 kg-1 and a mean apparent volume of distribution of 21 l kg-1.	Amlodipine	30-40	CD59 molecule (CD59 blood group)	Homo sapiens	140-150
2873746-3	1986	The fractional turnover rates of the tracer-miscible glutamate and glutamine pools were fast, 8.0 and 2.8% min-1, respectively.	Glutamic Acid	53-62	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
2873746-3	1986	The fractional turnover rates of the tracer-miscible glutamate and glutamine pools were fast, 8.0 and 2.8% min-1, respectively.	Glutamine	67-76	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
3741288-8	1986	HR (degree C X min-1) was the most sensitive index of drug activity with a 200 micrograms X kg-1 dose (equivalent to 2 mg in man for organophosphate poisoning) eliciting an increased HR from 0.022 degrees C (saline) to 0.087 degrees C X min-1 (atropine).	Organophosphates	133-148	CD59 molecule (CD59 blood group)	Homo sapiens	237-242
3741288-8	1986	HR (degree C X min-1) was the most sensitive index of drug activity with a 200 micrograms X kg-1 dose (equivalent to 2 mg in man for organophosphate poisoning) eliciting an increased HR from 0.022 degrees C (saline) to 0.087 degrees C X min-1 (atropine).	Sodium Chloride	208-214	CD59 molecule (CD59 blood group)	Homo sapiens	237-242
3519651-3	1986	Endogenous glucose production declined from 2.71 +/- 0.20 mg kg-1 min-1 to 1.75 + 0.26 (P less than 0.01) and glucose utilization from 2.71 +/- 0.20 to 1.98 +/- 0.17 mg kg-1 min-1 (P less than 0.01), while blood glucose was maintained at the initial level by the infusion of glucose.	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
3104512-7	1986	nitroglycerin, administered continuously at the dose of 0.7 microgram/kg-1/min-1, optimizes myocardial oxygenation during surgery and minimizes the risk of intraoperative myocardial ischemia.	Nitroglycerin	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
3543359-6	1986	Spectral data were used to calculate a rate constant of (5.4 +/- 0.3) X 10(-3) min-1 for the intracellular disappearance of 4 at 23 degrees C. The intracellular pH was determined to be 7.1 from the chemical shift of the internal inorganic phosphate signal.	Phosphates	239-248	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
3464138-8	1986	Infusion of PGF2 alpha (.5 micrograms min-1 and 1.0 microgram X min-1 for ten minutes) into the femoral artery resulted in a significant increase in the frequency of events less than 180 seconds in both the myometrium and cervix.	Dinoprost	12-22	CD59 molecule (CD59 blood group)	Homo sapiens	38-49
3464138-8	1986	Infusion of PGF2 alpha (.5 micrograms min-1 and 1.0 microgram X min-1 for ten minutes) into the femoral artery resulted in a significant increase in the frequency of events less than 180 seconds in both the myometrium and cervix.	Dinoprost	12-22	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
2872219-8	1986	In inhibitor protein-depleted oligomycin-sensitive Triton extracts, lauryl dimethylamine oxide stimulates ATP hydrolysis to very high values (30 mumol min-1 mg-1).	Oligomycins	30-40	CD59 molecule (CD59 blood group)	Homo sapiens	151-161
2872219-8	1986	In inhibitor protein-depleted oligomycin-sensitive Triton extracts, lauryl dimethylamine oxide stimulates ATP hydrolysis to very high values (30 mumol min-1 mg-1).	dodecyldimethylamine oxide	68-94	CD59 molecule (CD59 blood group)	Homo sapiens	151-161
2872219-8	1986	In inhibitor protein-depleted oligomycin-sensitive Triton extracts, lauryl dimethylamine oxide stimulates ATP hydrolysis to very high values (30 mumol min-1 mg-1).	Adenosine Triphosphate	106-109	CD59 molecule (CD59 blood group)	Homo sapiens	151-161
3717636-4	1986	N-pentane elimination rates (mean +/- SEM) in the expired gas at 0, 30, 60, 90, and 120 min were 10.2 +/- 1.5, 1.6 +/- 0.2, 1.2 +/- 0.9, 1.3 +/- 0.4, and 1.3 +/- 0.3 (pmol X kg-1 X min-1), respectively.	pentane	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
2874117-6	1986	After three months" labetalol (alpha + beta-blocker) administration, the antipyrine half-time decreased from the average 18.5 +/- 5.1 to 15.0 +/- 4.4 h (p less than 0.05), whereas its clearance increased from 30.3 +/- 2.7 to 36.3 +/- 10.8 min-1 (p less than 0.05).	Labetalol	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	239-244
3517029-4	1986	Mean glucose disposal was 34 +/- 11, 69 +/- 10, and 84 +/- 22 mumol kg-1 min-1 in N and 16 +/- 5, 40 +/- 18, and 65 +/- 27 in IDDM, respectively.	Glucose	5-12	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
3701338-3	1986	The kinetically determined dissociation constant for high-affinity binding of toxin is 0.56 nM (k1 = 6.3 X 10(-3) min-1 nM-1; k-1 = 3.5 X 10(-3) min-1) at 20 degrees C. Nicotine, d-tubocurarine, and acetylcholine are among the most effective inhibitors of high-affinity toxin binding.	Nicotine	169-177	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
3701338-3	1986	The kinetically determined dissociation constant for high-affinity binding of toxin is 0.56 nM (k1 = 6.3 X 10(-3) min-1 nM-1; k-1 = 3.5 X 10(-3) min-1) at 20 degrees C. Nicotine, d-tubocurarine, and acetylcholine are among the most effective inhibitors of high-affinity toxin binding.	Nicotine	169-177	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
3701338-3	1986	The kinetically determined dissociation constant for high-affinity binding of toxin is 0.56 nM (k1 = 6.3 X 10(-3) min-1 nM-1; k-1 = 3.5 X 10(-3) min-1) at 20 degrees C. Nicotine, d-tubocurarine, and acetylcholine are among the most effective inhibitors of high-affinity toxin binding.	Tubocurarine	179-193	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
3701338-3	1986	The kinetically determined dissociation constant for high-affinity binding of toxin is 0.56 nM (k1 = 6.3 X 10(-3) min-1 nM-1; k-1 = 3.5 X 10(-3) min-1) at 20 degrees C. Nicotine, d-tubocurarine, and acetylcholine are among the most effective inhibitors of high-affinity toxin binding.	Tubocurarine	179-193	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
3701338-3	1986	The kinetically determined dissociation constant for high-affinity binding of toxin is 0.56 nM (k1 = 6.3 X 10(-3) min-1 nM-1; k-1 = 3.5 X 10(-3) min-1) at 20 degrees C. Nicotine, d-tubocurarine, and acetylcholine are among the most effective inhibitors of high-affinity toxin binding.	Acetylcholine	199-212	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
3701338-3	1986	The kinetically determined dissociation constant for high-affinity binding of toxin is 0.56 nM (k1 = 6.3 X 10(-3) min-1 nM-1; k-1 = 3.5 X 10(-3) min-1) at 20 degrees C. Nicotine, d-tubocurarine, and acetylcholine are among the most effective inhibitors of high-affinity toxin binding.	Acetylcholine	199-212	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
3090845-3	1986	Alfentanil was given before intubation (1 mg), as a loading dose before starting surgery (50 micrograms kg-1) and by a continuous infusion at a rate of 1 microgram kg-1 min-1.	Alfentanil	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
3083850-1	1986	The insufflation of oxygen at 1 litre kg-1 min-1 via two endobronchial catheters (called continuous flow ventilation (CFV)) maintained a normal PaCO2 and a constant PaO2 in anaesthetized paralysed dogs and in five out of seven cats.	Oxygen	20-26	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
3083850-3	1986	In five patients, endobronchial insufflation of oxygen 0.5 litre kg-1 min-1 caused approximately a 30% decrease in the increase in PaCO2 compared with apnoeic oxygenation (P less than 0.05) during a period of 6 min.	Oxygen	48-54	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
3083850-3	1986	In five patients, endobronchial insufflation of oxygen 0.5 litre kg-1 min-1 caused approximately a 30% decrease in the increase in PaCO2 compared with apnoeic oxygenation (P less than 0.05) during a period of 6 min.	paco2	131-136	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
3730521-3	1986	The systemic clearance of bromopride was 899 ml min-1 +/- 22 per cent CV, the volume of distribution was 2151 +/- 16 per cent CV, and the elimination half-life was 2.9 h +/- 21 per cent CV.	bromopride	26-36	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
3719434-4	1986	The benzoylcholine hydrolysis rates in the plasma of ten patients who received an esmolol infusion of 500 micrograms.kg-1.min-1 for 4 minutes were 58.6 +/- 6.2 mumol.hr-1.ml-1 (mean +/- SE) before and 55.1 +/- 6.6 mumol.hr-1.ml-1 after the infusion.	Benzoylcholine	4-18	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
3719434-4	1986	The benzoylcholine hydrolysis rates in the plasma of ten patients who received an esmolol infusion of 500 micrograms.kg-1.min-1 for 4 minutes were 58.6 +/- 6.2 mumol.hr-1.ml-1 (mean +/- SE) before and 55.1 +/- 6.6 mumol.hr-1.ml-1 after the infusion.	esmolol	82-89	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
3457670-6	1986	After indomethacin, fractional free water clearance was reduced by an average of 26% at the zero, 2 and 4 fmol min-1 kg-1 infusion rates of AVP.	Indomethacin	6-18	CD59 molecule (CD59 blood group)	Homo sapiens	111-121
3457670-6	1986	After indomethacin, fractional free water clearance was reduced by an average of 26% at the zero, 2 and 4 fmol min-1 kg-1 infusion rates of AVP.	Water	36-41	CD59 molecule (CD59 blood group)	Homo sapiens	111-121
3457670-8	1986	After indomethacin, urinary prostaglandin E2 (PGE2) excretion rate was reduced by an average of 40% at the zero and 2 fmol min-1 kg-1 infusion rates of AVP.	Indomethacin	6-18	CD59 molecule (CD59 blood group)	Homo sapiens	123-133
3457670-8	1986	After indomethacin, urinary prostaglandin E2 (PGE2) excretion rate was reduced by an average of 40% at the zero and 2 fmol min-1 kg-1 infusion rates of AVP.	Dinoprostone	28-44	CD59 molecule (CD59 blood group)	Homo sapiens	123-133
3457670-8	1986	After indomethacin, urinary prostaglandin E2 (PGE2) excretion rate was reduced by an average of 40% at the zero and 2 fmol min-1 kg-1 infusion rates of AVP.	Dinoprostone	46-50	CD59 molecule (CD59 blood group)	Homo sapiens	123-133
3514331-8	1986	The mean glucose utilization rate (4.70 +/- 0.36 mg X kg-1 X min-1 preglucagon) was significantly decreased by glucagon replacement (3.83 +/- 0.31 mg X kg-1 X min-1, P less than 0.02).	Glucose	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
3514331-8	1986	The mean glucose utilization rate (4.70 +/- 0.36 mg X kg-1 X min-1 preglucagon) was significantly decreased by glucagon replacement (3.83 +/- 0.31 mg X kg-1 X min-1, P less than 0.02).	Glucose	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
3514331-8	1986	The mean glucose utilization rate (4.70 +/- 0.36 mg X kg-1 X min-1 preglucagon) was significantly decreased by glucagon replacement (3.83 +/- 0.31 mg X kg-1 X min-1, P less than 0.02).	Glucagon	70-78	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
3514331-9	1986	Mean glucose clearance was also diminished with glucagon (4.49 +/- 0.32 versus 5.73 +/- 0.45 ml X kg-1 X min-1 preglucagon, P less than 0.02).	Glucagon	48-56	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
3732428-4	1986	The four patients in whom the PPA indices were reduced to below 0.5 X 10(-3) min-1 within 1 h of completion of MP infusion all survived.	ppa	30-33	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
3710978-4	1986	Alveolar-to-arterial O2 tension difference increased linearly with O2 uptake (VO2) (6.1 Torr X min-1 X 1(-1) VO2).	Oxygen	21-23	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
3710978-4	1986	Alveolar-to-arterial O2 tension difference increased linearly with O2 uptake (VO2) (6.1 Torr X min-1 X 1(-1) VO2).	Oxygen	67-69	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
3710978-4	1986	Alveolar-to-arterial O2 tension difference increased linearly with O2 uptake (VO2) (6.1 Torr X min-1 X 1(-1) VO2).	vo2	78-81	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
3710978-4	1986	Alveolar-to-arterial O2 tension difference increased linearly with O2 uptake (VO2) (6.1 Torr X min-1 X 1(-1) VO2).	vo2	109-112	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
2938871-4	1986	Sodium excretion trebled (P = less than 0.005) during the infusion of a calculated dose of 15 pmol of alpha-h-ANP min-1 kg-1 and there was an accompanying diuresis; radioimmunoassay of plasma alpha-h-ANP during the natriuresis indicated a mean peak incremental concentration of 203 +/- 78 (SEM) pmol/l.	Sodium	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	114-124
2938871-4	1986	Sodium excretion trebled (P = less than 0.005) during the infusion of a calculated dose of 15 pmol of alpha-h-ANP min-1 kg-1 and there was an accompanying diuresis; radioimmunoassay of plasma alpha-h-ANP during the natriuresis indicated a mean peak incremental concentration of 203 +/- 78 (SEM) pmol/l.	NPPA protein, human	102-113	CD59 molecule (CD59 blood group)	Homo sapiens	114-124
3698511-2	1986	Four incremental infusion rates (4, 10, 25 and 62.5 ng min-1 kg-1) produced circulating catecholamine concentrations within the physiological range.	Catecholamines	88-101	CD59 molecule (CD59 blood group)	Homo sapiens	55-65
3956133-4	1986	Decreases in the water thermal gradient (from 6.06 to 5.33 degrees C, P less than 0.05) in maximal value of heat loss (from 22.5 to 18.75 w.m-2, P less than 0.01) and in plethysmographic wave amplitude (from 25.8 to 14.6 mm, P less than 0.01) and increased HR (from 72 to 83 beats min-1) were observed in smokers.	Water	17-22	CD59 molecule (CD59 blood group)	Homo sapiens	281-286
3945245-3	1986	Oxalate exchange was significantly higher in the 98 patients with idiopathic stone formation than in the controls (-1.10 +/- 0.95 [SD] X 10(-2) min-1 vs. -0.31 +/- 0.12 X 10(-2); P less than 0.001); it was above the upper limits of normal in 78 of these patients.	Oxalates	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
2421751-5	1986	Compared to baseline, xamoterol (0.025 mg kg-1) increased heart rate (61 +/- 3-68 +/- 3 beats min-1, means and SEM) and systolic blood pressure (119 +/- 3-138 +/- 5 mm Hg) but decreased pre-ejection period (100 +/- 4-76 +/- 5 msec).	Xamoterol	22-31	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
3511930-13	1986	One patient in the metoprolol group had marked bradycardia (minimum heart rate 26 beat min-1) after neostigmine and atropine; otherwise metoprolol pretreatment was tolerated well.	Metoprolol	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
3519651-3	1986	Endogenous glucose production declined from 2.71 +/- 0.20 mg kg-1 min-1 to 1.75 + 0.26 (P less than 0.01) and glucose utilization from 2.71 +/- 0.20 to 1.98 +/- 0.17 mg kg-1 min-1 (P less than 0.01), while blood glucose was maintained at the initial level by the infusion of glucose.	Glucose	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
3519651-8	1986	During control euglycemic hyperinsulinemic clamps (1 and 10 mU kg-1 min-1 insulin infusion), endogenous glucose production was suppressed at the lowest insulin infusion rate; glucose utilization increased first to 7.32 +/- 0.96 mg kg-1 min-1 and then to 16.5 +/- 1.27 mg kg-1 min-1.	Glucose	104-111	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
3519651-8	1986	During control euglycemic hyperinsulinemic clamps (1 and 10 mU kg-1 min-1 insulin infusion), endogenous glucose production was suppressed at the lowest insulin infusion rate; glucose utilization increased first to 7.32 +/- 0.96 mg kg-1 min-1 and then to 16.5 +/- 1.27 mg kg-1 min-1.	Glucose	175-182	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
3519651-9	1986	During euglycemic hyperinsulinemic clamps with simultaneous sodium acetoacetate infusion, similar insulin levels were attained; endogenous glucose production was also suppressed at the lowest insulin infusion rate, and insulin-stimulated glucose utilization rates (7.93 +/- 1.70 and 15.80 +/- 1.30 mg kg-1 min-1) were not modified.	Glucose	238-245	CD59 molecule (CD59 blood group)	Homo sapiens	306-311
3511062-11	1986	With Ala-Ala-Phe-4-methyl-7-coumarylamide, Km was 16 microM and Vmax 13 mumol min-1 .	ala-ala-phe-4-methyl-7-coumarylamide	5-41	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
2935532-3	1986	The reconstituted vesicles exhibited ATP-dependent oxalate-facilitated Ca2+ accumulation with rates and efficiency comparable to the best reconstituted skeletal muscle preparation (Ca2+-loading rate = 1.65 +/- 0.31 mumol mg-1 min-1, Ca2+-activated ATPase activity = 2.39 +/- 0.25 mumol mg-1 min-1, efficiency (Ca2+/ATP) = 0.69 +/- 0.09).	Oxalates	51-58	CD59 molecule (CD59 blood group)	Homo sapiens	226-231
2935532-3	1986	The reconstituted vesicles exhibited ATP-dependent oxalate-facilitated Ca2+ accumulation with rates and efficiency comparable to the best reconstituted skeletal muscle preparation (Ca2+-loading rate = 1.65 +/- 0.31 mumol mg-1 min-1, Ca2+-activated ATPase activity = 2.39 +/- 0.25 mumol mg-1 min-1, efficiency (Ca2+/ATP) = 0.69 +/- 0.09).	Oxalates	51-58	CD59 molecule (CD59 blood group)	Homo sapiens	291-296
2937338-5	1986	The pulse rate following intubation showed a smaller rise (P less than 0.001) with alfentanil of 26 (SD 14.6) beats min-1, than the normal saline group of 46 (SD 13.3) beats min-1.	Alfentanil	83-93	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
3753829-3	1986	Patients receiving enflurane anesthesia required atracurium at an infusion rate of 4.9 +/- 0.3 micrograms X kg-1 X min-1 which was a significantly lower rate (P = 0.0001) than those anesthetized with halothane (8.3 +/- 0.4 micrograms X kg-1 X min-1) or with N2O:O2 and narcotic (9.3 +/- 0.5 micrograms X kg-1 X min-1).	Enflurane	19-28	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
3753829-3	1986	Patients receiving enflurane anesthesia required atracurium at an infusion rate of 4.9 +/- 0.3 micrograms X kg-1 X min-1 which was a significantly lower rate (P = 0.0001) than those anesthetized with halothane (8.3 +/- 0.4 micrograms X kg-1 X min-1) or with N2O:O2 and narcotic (9.3 +/- 0.5 micrograms X kg-1 X min-1).	Enflurane	19-28	CD59 molecule (CD59 blood group)	Homo sapiens	243-248
3753829-3	1986	Patients receiving enflurane anesthesia required atracurium at an infusion rate of 4.9 +/- 0.3 micrograms X kg-1 X min-1 which was a significantly lower rate (P = 0.0001) than those anesthetized with halothane (8.3 +/- 0.4 micrograms X kg-1 X min-1) or with N2O:O2 and narcotic (9.3 +/- 0.5 micrograms X kg-1 X min-1).	Enflurane	19-28	CD59 molecule (CD59 blood group)	Homo sapiens	243-248
3753829-3	1986	Patients receiving enflurane anesthesia required atracurium at an infusion rate of 4.9 +/- 0.3 micrograms X kg-1 X min-1 which was a significantly lower rate (P = 0.0001) than those anesthetized with halothane (8.3 +/- 0.4 micrograms X kg-1 X min-1) or with N2O:O2 and narcotic (9.3 +/- 0.5 micrograms X kg-1 X min-1).	Atracurium	49-59	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
3458447-4	1986	The mean maximum oxygen uptake (VO2max) of the CAPD patients was reduced considerably (14.6 ml kg-1 min-1) compared with matched control subjects (33.6 ml kg-1 min-1).	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
3954935-2	1986	In patients with cirrhosis, the dose of isoprenaline required to increase the resting heart rate by 25 beats min-1 (chronotropic dose 25 or CD25) ranged from 2.50 to 34.73 micrograms (median: 4.47 micrograms) and was significantly higher than in controls (range: 0.66 to 2.76 micrograms, median: 1.34 micrograms).	Isoproterenol	40-52	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
3954939-5	1986	In two patients taking dipyridamole the mean dose of adenosine which produced an electrophysiologic effect (restoration of sinus rhythm or ventricular slowing to under 100 beats min-1) was 1.0 +/- 0.52 mg, whereas in other patients the mean dose was 8.8 +/- 2.6 mg, suggesting potentiation of the action of adenosine by dipyridamole.	Dipyridamole	23-35	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
3954939-5	1986	In two patients taking dipyridamole the mean dose of adenosine which produced an electrophysiologic effect (restoration of sinus rhythm or ventricular slowing to under 100 beats min-1) was 1.0 +/- 0.52 mg, whereas in other patients the mean dose was 8.8 +/- 2.6 mg, suggesting potentiation of the action of adenosine by dipyridamole.	Adenosine	53-62	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
3698349-4	1986	Low serum albumin in NS patients induced a twofold increase of unbound warfarin vs controls (3.5% vs 1.8%, p less than 0.001) which led to a threefold increase in plasma clearance of warfarin (9.70 vs 3.26 ml X min-1, p less than 0.001); as warfarin distribution volume showed only a slight (non significant) increase in NS patients, the elimination half-life was thus markedly shortened in NS patients vs controls (18 vs 36 h, p less than 0.01).	Warfarin	71-79	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
3698349-4	1986	Low serum albumin in NS patients induced a twofold increase of unbound warfarin vs controls (3.5% vs 1.8%, p less than 0.001) which led to a threefold increase in plasma clearance of warfarin (9.70 vs 3.26 ml X min-1, p less than 0.001); as warfarin distribution volume showed only a slight (non significant) increase in NS patients, the elimination half-life was thus markedly shortened in NS patients vs controls (18 vs 36 h, p less than 0.01).	Warfarin	183-191	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
3698349-4	1986	Low serum albumin in NS patients induced a twofold increase of unbound warfarin vs controls (3.5% vs 1.8%, p less than 0.001) which led to a threefold increase in plasma clearance of warfarin (9.70 vs 3.26 ml X min-1, p less than 0.001); as warfarin distribution volume showed only a slight (non significant) increase in NS patients, the elimination half-life was thus markedly shortened in NS patients vs controls (18 vs 36 h, p less than 0.01).	Warfarin	183-191	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
3516703-4	1986	Compared to measurements taken during a baseline phase of 15 min duration, pirmenol increased heart rate by 10 beats min-1 (P less than 0.001) and mean arterial pressure (MAP) by 5 mmHg (P less than 0.001).	pirmenol	75-83	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
3699302-3	1986	In the post-absorptive state, the mean total ketone body appearance rate, determined in four subjects, was 3.74 mumol X kg-1 X min-1 using [3,4-13C2] acetoacetate and 2.76 mumol X kg-1 X min-1 using [3-13C]D-beta-hydroxybutyrate, values in agreement with those reported in studies with 14C-labelled tracers.	Ketones	45-51	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
3699302-3	1986	In the post-absorptive state, the mean total ketone body appearance rate, determined in four subjects, was 3.74 mumol X kg-1 X min-1 using [3,4-13C2] acetoacetate and 2.76 mumol X kg-1 X min-1 using [3-13C]D-beta-hydroxybutyrate, values in agreement with those reported in studies with 14C-labelled tracers.	Ketones	45-51	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
3558757-4	1986	On the basis of measurements of ovine granulosa cell respiration in vitro, the model predicts that a large pre-antral follicle with a radius of 0.15 mm consumes oxygen at the rate of 0.22 nmol min-1.	Oxygen	161-167	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
3949654-5	1986	New male and female recruits representing a young civilian population entered the service with maximal O2 uptake of 51 and 37 ml X kg body wt-1 X min-1, respectively, and thereafter increased 5% during initial basic training.	Oxygen	103-105	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
3083482-4	1986	Cyclo-oxygenase was inhibited by infusion of meclofenamate (60 micrograms X min-1) which consistently abolished the vasodilator responses to arachidonic acid added to the donor.	Meclofenamic Acid	45-58	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
3083482-4	1986	Cyclo-oxygenase was inhibited by infusion of meclofenamate (60 micrograms X min-1) which consistently abolished the vasodilator responses to arachidonic acid added to the donor.	Arachidonic Acid	141-157	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
3510558-6	1986	min-1 insulin infusion using 6,6-dideuteroglucose.	6,6-dideuteroglucose	29-49	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
2868747-8	1986	After intravenous administration most of the effect was present after 0.5 h but the maximum effect (-33 beats min-1) was only reached at 3 h. Bopindolol possesses a long duration of action: after 48 h 33% of the maximum effect of the oral dose of 4 mg was still present.	bopindolol	142-152	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
2871854-5	1986	The blood pressure reduction produced by doxazosin was associated in the young with a significant increase in heart rate to 108 beats min-1 (placebo, 82 beats min-1) but this increase was significantly attenuated in the elderly at 91 beats min-1 (placebo, 77 beats min-1).	Doxazosin	41-50	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
2871854-5	1986	The blood pressure reduction produced by doxazosin was associated in the young with a significant increase in heart rate to 108 beats min-1 (placebo, 82 beats min-1) but this increase was significantly attenuated in the elderly at 91 beats min-1 (placebo, 77 beats min-1).	Doxazosin	41-50	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
2871854-5	1986	The blood pressure reduction produced by doxazosin was associated in the young with a significant increase in heart rate to 108 beats min-1 (placebo, 82 beats min-1) but this increase was significantly attenuated in the elderly at 91 beats min-1 (placebo, 77 beats min-1).	Doxazosin	41-50	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
2871854-5	1986	The blood pressure reduction produced by doxazosin was associated in the young with a significant increase in heart rate to 108 beats min-1 (placebo, 82 beats min-1) but this increase was significantly attenuated in the elderly at 91 beats min-1 (placebo, 77 beats min-1).	Doxazosin	41-50	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
2939866-2	1986	In group I, stepwise increasing doses of doxazosin were associated with increases in renal perfusion and, at doses above 1 microgram kg-1 min-1, also with a fall in blood pressure.	Doxazosin	41-50	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
3004546-4	1986	In patients with severe renal impairment (GFR values below 30 ml min-1 1.73 m-2) significantly smaller doses of enalapril maleate will be required than in patients with normal or less severely impaired renal function.	Enalapril	112-129	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
3095111-7	1986	With the highest dose of verapamil, maximal heart rate was reduced by 13 +/- 1 beats X min-1.	Verapamil	25-34	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
3698986-4	1986	During weight lifting, mean oxygen uptake and heart rate were 1.96 L X min-1 and 158 bt X min-1, respectively.	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	71-95
3699008-2	1986	On the morning after a previous day"s "low-energy" intake (LE regimen) of 4.5 MJ, the mean resting oxygen consumption increased by 0.7 ml X kg-1 X min-1 after the test meal (P less than 0.025).	Oxygen	99-105	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
3699008-6	1986	Oxygen consumption during exercise increased after feeding by 0.5 ml X kg-1 X min-1 on the LE regimen (n.s.)	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
3699008-7	1986	and decreased by 1.2 ml X kg-1 X min-1 on the HE regimen (n.s.).	Helium	46-48	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
3758042-8	1986	Gross VO2max (l X min-1) and mass standardised VO2max (ml X min-1 X kg-1) were both negatively correlated to cortisol levels after the race (p less than 0.05).	Hydrocortisone	109-117	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
3816927-6	1986	The renal clearance of sulphinpyrazone varied from 14-40 ml X min-1 (mean: 28 ml X min-1).	Sulfinpyrazone	23-38	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
3816927-6	1986	The renal clearance of sulphinpyrazone varied from 14-40 ml X min-1 (mean: 28 ml X min-1).	Sulfinpyrazone	23-38	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
3816927-8	1986	The same holds for the sulphone metabolite, which has a mean renal clearance of 24 ml X min-1, and even more for the p-hydroxysulphinpyrazone metabolite, which has a renal clearance of 118 ml X min-1.	Sulfones	23-31	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
3816927-8	1986	The same holds for the sulphone metabolite, which has a mean renal clearance of 24 ml X min-1, and even more for the p-hydroxysulphinpyrazone metabolite, which has a renal clearance of 118 ml X min-1.	p-hydroxysulphinpyrazone	117-141	CD59 molecule (CD59 blood group)	Homo sapiens	194-199
3956523-2	1986	Felodipine was an effective arteriolar vasodilator producing increases in cardiac index from 2.6 +/- 0.1 to 3.5 +/- 0.2 l min-1 m-2 (P less than 0.001) and stroke volume 35.3 +/- 2.7 to 41.4 +/- 2.4 ml beat-1 m-2 (P less than 0.002).	Felodipine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
3732379-4	1986	Paracetamol t1/2 significantly decreased from 2.1 to 0.96 h and clearance rate (CL) significantly increased from 8.7 to 17.0 ml min-1 kg-1, when compared with the preoperative values.	Acetaminophen	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	128-138
3743613-4	1986	In patients receiving 20 mg of nicardipine, mean cardiac index rose to a peak 1.81 X min-1 X m-2 (64%) above the preinfusion level, stroke volume index rose by 12 ml X m-2 (35%) and heart rate rose by 16 beats X min-1 (20%).	Nicardipine	31-42	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
3743613-4	1986	In patients receiving 20 mg of nicardipine, mean cardiac index rose to a peak 1.81 X min-1 X m-2 (64%) above the preinfusion level, stroke volume index rose by 12 ml X m-2 (35%) and heart rate rose by 16 beats X min-1 (20%).	Nicardipine	31-42	CD59 molecule (CD59 blood group)	Homo sapiens	212-217
3780831-2	1986	Disopyramide 100 and 150 mg was given intravenously as a bolus to the patients with IHD and DHF, respectively, followed by a continuous infusion of disopyramide 0.3 (DHF group) and 0.4 mg X min-1 (IHD group) until steady-state was achieved.	Disopyramide	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
3944260-2	1986	Ketone body inflow-outflow transport (flux) averaged 17.3 +/- 1.4 mumol kg-1 min-1 in the neonates, a value not different from that of 20.6 +/- 0.9 mumol kg-1 min-1 measured in the older infants.	Ketones	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
3944260-5	1986	Compared with the adult, however, ketone body turnover rates of 12.8-21.9 mumol kg-1 min-1 in newborns fasted for less than 8 h, and rates of 17.9-26.0 mumol kg-1 min-1 in older infants fasted for less than 10 h, were in a range found in adults only after several days of total fasting.	Ketones	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
3949375-6	1986	In subjects with pretreatment glomerular filtration rates of 80 ml/min/1.73 m2 or less, diltiazem therapy was associated with marked improvement in glomerular filtration rate (48%) and effective renal plasma flow (36%).	Diltiazem	88-97	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
3941355-1	1986	In a retrospective study of 39 normal children submitted to [123I]hippuran gamma camera renography, a quantitative evaluation of the recorded data showed that: (a) the rate constant for renal plasma clearance of [123I]hippuran was -0.166 +/- 0.043 min-1 corresponding to a hippuran plasma clearance of 518 +/- 142 ml/min per 1.73 m2; (b) the fractional renal clearance of [123I]hippuran was 0.51 +/- 0.03 and 0.49 +/- 0.03 for the left and the right kidney, respectively; and (c) the mean values for the mean transit times of [123I]hippuran through the whole kidney, the renal parenchyma, and the renal pelvis, respectively, were 4.2, 1.9, and 2.5 min.	Iodohippuric Acid	218-226	CD59 molecule (CD59 blood group)	Homo sapiens	248-253
3941355-1	1986	In a retrospective study of 39 normal children submitted to [123I]hippuran gamma camera renography, a quantitative evaluation of the recorded data showed that: (a) the rate constant for renal plasma clearance of [123I]hippuran was -0.166 +/- 0.043 min-1 corresponding to a hippuran plasma clearance of 518 +/- 142 ml/min per 1.73 m2; (b) the fractional renal clearance of [123I]hippuran was 0.51 +/- 0.03 and 0.49 +/- 0.03 for the left and the right kidney, respectively; and (c) the mean values for the mean transit times of [123I]hippuran through the whole kidney, the renal parenchyma, and the renal pelvis, respectively, were 4.2, 1.9, and 2.5 min.	Iodohippuric Acid	218-226	CD59 molecule (CD59 blood group)	Homo sapiens	248-253
3953118-3	1986	The new process is based on the idea to use the late phase of high temperature for the evocation of the detected connection process of blood microcirculation by a supply of 25 l min-1 of pure oxygen lasting 25 minutes (via a mask applicator).	Oxygen	192-198	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
2417625-3	1985	55 degrees C and between p2H 7 and 9, where the opening rates of the structure fluctuations which promote the exchange of these protons are of the order 0.1 min-1.	1-(2-Hydroxy-2,2-Diphosphonoethyl)-3-Phenylpyridinium	25-28	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
2418616-8	1985	The exit rate constant of free iodide for the various doses showed values from 0.048 to 0.055 min-1.	Iodides	31-37	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
2418616-9	1985	Corresponding mean values for the discharge rate constant after perchlorate were 0.087 to 0.105 min-1.	perchlorate	64-75	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
2868743-6	1985	In Study 2 adrenaline 0.05 micrograms kg-1 min-1 was infused for 80 min preceded by either idazoxan or vehicle.	Epinephrine	11-21	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
3878717-2	1985	Intermittent bolus administration of both agents proved a feasible way of maintaining anaesthesia, a mean infusion rate of 0.13 mg kg-1 min-1 being required for propofol and 0.089 mg kg-1 min-1 for methohexitone.	Methohexital	198-211	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
3912001-2	1985	During graded intravenous administration of PGI2, platelet aggregation was inhibited at a minimum dose of 4 ng kg-1 min-1.	Epoprostenol	44-48	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
3912001-3	1985	The dose required to produce the same degree of platelet inhibition was approximately 15 ng kg-1 min-1 for 6-keto-PGE1.	6-ketoprostaglandin E1	107-118	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
3912001-4	1985	Diastolic BP was significantly reduced and PRA was increased by PGI2 at a dose greater than 8 ng kg-1 min-1.	Epoprostenol	64-68	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
3936526-6	1985	The slope of the carbon dioxide response under light nitrous oxide-halothane anaesthesia (0.5% halothane) was relatively flat (18.64 ml min-1 kg-1 mm Hg-1) when compared with the mean values published for anaesthetized adults, children or neonates.	Carbon Dioxide	17-31	CD59 molecule (CD59 blood group)	Homo sapiens	136-146
3830711-1	1985	Although anterograde conduction through a Kent bundle with a short refractory period was suppressed by 300 mg of flecainide acetate, the infusion of small amounts of isoproterenol caused the reappearance of WPW and permitted the induction of an atrial tachycardia with 1/1 conduction through the accessory pathway at a rate of 260 beats min-1.	Isoproterenol	166-179	CD59 molecule (CD59 blood group)	Homo sapiens	337-342
3938405-4	1985	Compensated cirrhotic patients showed a normal baseline sodium and water balance but a blunted natriuretic response when saline loaded (urinary sodium excretion after saline load = 338 +/- 290 compared to 933 +/- 504 mumol min-1 of controls; P less than 0.05).	Sodium Chloride	121-127	CD59 molecule (CD59 blood group)	Homo sapiens	223-228
2415587-3	1985	In addition, 1F5 induces a moderate increase in thymidine uptake, which is accompanied by enhanced viability of the cells, but not by any increase in total cell number or by any detectable entry into S phase or mitosis.	Thymidine	48-57	CD59 molecule (CD59 blood group)	Homo sapiens	13-16
2415587-5	1985	The fact that all the changes observed can be inhibited by low concentrations (I50 = 50 ng/ml) of cyclosporin A is further evidence that 1F5 is involved at an early stage of B cell activation.	Cyclosporine	98-111	CD59 molecule (CD59 blood group)	Homo sapiens	137-140
3001275-5	1985	The association rate constant (k1) for [125I]PTA-OH was 6.6 X 10(6)M-1 min-1 and the dissociation rate constant (k-1) was 1.82 X 10(-1), yielding a kinetically determined Kd (k-1/k1) of 27 nM.	pta-oh	45-51	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
4067776-2	1985	The mean absorption rates of glucose and galactose were 26.5 and 43.8 mumol min-1 30 cm-1, respectively, and were significantly reduced (p less than 0.001) to 13 and 22%, respectively, of intake.	Glucose	29-36	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
4067776-2	1985	The mean absorption rates of glucose and galactose were 26.5 and 43.8 mumol min-1 30 cm-1, respectively, and were significantly reduced (p less than 0.001) to 13 and 22%, respectively, of intake.	Galactose	41-50	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
4067776-3	1985	On the other hand, the absorption of fructose was 133.3 mumol min-1 30 cm-1, i.e., as high as in the controls.	Fructose	37-45	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
4067776-4	1985	The hydrolysis rate of lactose was also normal (134.0 mumol min-1 30 cm-1).	Lactose	23-30	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
4083044-7	1985	From start of exercise the average rates of glycogen depletion in type I fibres were about 1.0, 2.0 and 4.3 mmol glucosyl units kg-1 (w/w) min-1 at 43%, 61% and 91% of VO2max.	Glycogen	44-52	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
3877468-5	1985	Ouabain caused Aab to increase markedly to 303 neq/cm2 in 30 min, whereas amiloride inhibition of apical membrane Na+ entry reduced markedly the rate of increase of Aab caused by ouabain (7.3 neq X cm-2 X min-1 in control and 1.7 neq X cm-2 X min-1 in the presence of amiloride).	Amiloride	74-83	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
3877468-5	1985	Ouabain caused Aab to increase markedly to 303 neq/cm2 in 30 min, whereas amiloride inhibition of apical membrane Na+ entry reduced markedly the rate of increase of Aab caused by ouabain (7.3 neq X cm-2 X min-1 in control and 1.7 neq X cm-2 X min-1 in the presence of amiloride).	Amiloride	74-83	CD59 molecule (CD59 blood group)	Homo sapiens	243-248
3904407-4	1985	At follow-up, the group mean (+/- SD) serum creatinine concentration in 14 patients with functioning grafts was nearly double the expected mean value for normal children of similar age and sex (1.13 +/- 0.38 vs 0.61 +/- 0.07 mg/dL), and the mean +/- SD glomerular filtration rate was 76.5 +/- 20.0 mL/min/1.73 sq m (range, 40 to 115.5 mL/min/1.73 sq m).	Creatinine	44-54	CD59 molecule (CD59 blood group)	Homo sapiens	301-306
3904407-4	1985	At follow-up, the group mean (+/- SD) serum creatinine concentration in 14 patients with functioning grafts was nearly double the expected mean value for normal children of similar age and sex (1.13 +/- 0.38 vs 0.61 +/- 0.07 mg/dL), and the mean +/- SD glomerular filtration rate was 76.5 +/- 20.0 mL/min/1.73 sq m (range, 40 to 115.5 mL/min/1.73 sq m).	Creatinine	44-54	CD59 molecule (CD59 blood group)	Homo sapiens	338-343
4085516-5	1985	After three weeks of treatment with 200 mg metoprolol daily, the paced Q-T top interval increased significantly (3-4%, P less than 0.001) at all paced heart rates, while after about two weeks of treatment a significant increase was seen only at the paced heart rate of 130 beats min-1 (P less than 0.01).	Metoprolol	43-53	CD59 molecule (CD59 blood group)	Homo sapiens	279-284
2865217-5	1985	The time to pacing induced angina was prolonged (P less than 0.05) when the dose of nicardipine (0.75 mg X min-1) was selected not to cause an excessive fall in blood pressure.	Nicardipine	84-95	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
3903090-3	1985	Creatinine clearance was less than or equal to 80 ml/min/1.73 m2 in four patients.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
3008050-9	1985	Normal creatinine clearance range in children (80 to 120 ml min-1/1.73 m2) allowed determination of normal uptake range (36 to 60%).	Creatinine	7-17	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
4060156-2	1985	For brain samples, the bimolecular rate constant values (Ki) in the presence of acephate and methamidophos were 0.06 and 6.3 microM-1 X min-1, respectively.	acephate	80-88	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
4060156-2	1985	For brain samples, the bimolecular rate constant values (Ki) in the presence of acephate and methamidophos were 0.06 and 6.3 microM-1 X min-1, respectively.	methamidophos	93-106	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
4060156-5	1985	The Kp values in the presence of acephate and methamidophos for brain samples were 14.3 and 0.13 min-1, respectively.	acephate	33-41	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
4060156-5	1985	The Kp values in the presence of acephate and methamidophos for brain samples were 14.3 and 0.13 min-1, respectively.	methamidophos	46-59	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
4071455-2	1985	At an outlet flow of 2 l min-1 the mean % O2 generated by all models, except the Permox (which was lower, mean (SD) 90.5% (3.1%), were between 94% and 95% with a range of less than +/- 0.5%.	Oxygen	42-44	CD59 molecule (CD59 blood group)	Homo sapiens	25-30
3932340-11	1985	Incubation of the enzyme with 2,2"-dipyridyl disulfide caused inactivation in a biphasic manner with apparent second-order rate constants of 1230 M-1 min-1 and 235 M-1 min-1 for the rapid and slow phase, respectively.	2,2'-dipyridyl disulfide	30-54	CD59 molecule (CD59 blood group)	Homo sapiens	150-173
3930499-10	1985	The values of the first order rate constants for the subsequent decay process were 14.9 +/- 11.3 min-1 for indomethacin, 3.4 +/- 0.7 min-1 for meclofenamic acid, and 16.6 +/- 6.2 min-1 for flurbiprofen.	Indomethacin	107-119	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
3931553-9	1985	This process had an approximate K 1/2 for sodium of 10-20 mM and an approximate maximal rate of 50 nmol Ca mg-1 min-1.	Sodium	42-48	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Phenytoin	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Phenytoin	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	102-115
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Phenytoin	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Phenytoin	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Phenytoin	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Phenytoin	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Phenytoin	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Rifampin	50-60	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Rifampin	50-60	CD59 molecule (CD59 blood group)	Homo sapiens	102-115
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Rifampin	50-60	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Rifampin	50-60	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Rifampin	50-60	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Rifampin	50-60	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
4074601-4	1985	Clearance of phenytoin in patients receiving only rifampicin increased from 46.7 ml min-1 +/- 20.6 ml min-1 to 97.8 ml min-1 +/- 33.4 ml min-1 (P less than 0.01), while clearance in patients on three drugs increased from 47.1 +/- 23.4 ml min-1 to 81.3 ml min-1 +/- 41.6 ml min-1 (P less than 0.01).	Rifampin	50-60	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
4074606-2	1985	Felodipine produced a significant fall in diastolic blood pressure (DBP max = -15 mm Hg), a rise in heart rate (heart rate max = +15 beats min-1) (both P less than 0.01), and an overall fall in calculated forearm vascular resistance (calculated forearm vascular resistance max = -19.6 units, P less than 0.001).	Felodipine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
3935456-3	1985	During parenteral nutrition alanine turnover was significantly higher than in the post-abortive state (14.75 +/- 2.56 mumol kg-1 min-1 and 8.48 +/- 1.88 mumol kg-1 min-1, respectively; P less than 0.01, mean +/- s.d.).	Alanine	28-35	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
3905929-4	1985	glucose infusions of 0 (saline), 5 and 15 mg/kg X min-1.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
3905929-8	1985	glucose infusions of 5 and 15 mg/kg X min-1, but not when saline was infused.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
3932321-9	1985	At a neutral TA, increasing inspired [CO2] to 6% resulted in a 6-breaths X min-1 increase in f during both NBr and TBr.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	38-41	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
3932321-9	1985	At a neutral TA, increasing inspired [CO2] to 6% resulted in a 6-breaths X min-1 increase in f during both NBr and TBr.	nbr	107-110	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
4070370-6	1985	Tserng and Kalhan"s apparently conflicting results for glucose turnover using 13C-glucose as the tracer can all be shown to amount to approximately 11.6 mumol min-1 kg-1.	13c-glucose	78-89	CD59 molecule (CD59 blood group)	Homo sapiens	159-169
2413720-6	1985	Thus, the total amount of acid secreted is a function of histamine (released) exposure (M min-1) in the extracellular space.	Histamine	57-66	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
4057091-5	1985	The femoral arterial-venous oxygen difference at maximum work averaged 14.6% (v/v), resulting in an oxygen uptake of 0.80 l min-1.	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
2863325-4	1985	The overall decomposition rate for ibotenic acid (8.7 nmol min-1 mg-1 of protein), which apparently embraces other reactions in addition to decarboxylation to muscimol, was higher than the rate of decarboxylation of (S)-glutamic acid (3.2 nmol min-1 mg-1 of protein).	Ibotenic Acid	35-48	CD59 molecule (CD59 blood group)	Homo sapiens	59-69
2863325-4	1985	The overall decomposition rate for ibotenic acid (8.7 nmol min-1 mg-1 of protein), which apparently embraces other reactions in addition to decarboxylation to muscimol, was higher than the rate of decarboxylation of (S)-glutamic acid (3.2 nmol min-1 mg-1 of protein).	Ibotenic Acid	35-48	CD59 molecule (CD59 blood group)	Homo sapiens	244-254
2863325-4	1985	The overall decomposition rate for ibotenic acid (8.7 nmol min-1 mg-1 of protein), which apparently embraces other reactions in addition to decarboxylation to muscimol, was higher than the rate of decarboxylation of (S)-glutamic acid (3.2 nmol min-1 mg-1 of protein).	Muscimol	159-167	CD59 molecule (CD59 blood group)	Homo sapiens	59-69
2863325-4	1985	The overall decomposition rate for ibotenic acid (8.7 nmol min-1 mg-1 of protein), which apparently embraces other reactions in addition to decarboxylation to muscimol, was higher than the rate of decarboxylation of (S)-glutamic acid (3.2 nmol min-1 mg-1 of protein).	Glutamic Acid	216-233	CD59 molecule (CD59 blood group)	Homo sapiens	59-69
4057091-5	1985	The femoral arterial-venous oxygen difference at maximum work averaged 14.6% (v/v), resulting in an oxygen uptake of 0.80 l min-1.	Oxygen	100-106	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
4074667-3	1985	With purified, phospholipid-reconstituted BDH and NAD as the variable substrate, the apparent Km and Vmax values were respectively 0.25 mM and 62.5 mumol min-1 (mg of protein)-1.	Phospholipids	15-27	CD59 molecule (CD59 blood group)	Homo sapiens	154-177
4074667-3	1985	With purified, phospholipid-reconstituted BDH and NAD as the variable substrate, the apparent Km and Vmax values were respectively 0.25 mM and 62.5 mumol min-1 (mg of protein)-1.	NAD	50-53	CD59 molecule (CD59 blood group)	Homo sapiens	154-177
4074667-4	1985	With N3-NAD as the variable substrate, these values were respectively 0.59 mM and 5 mumol min-1 (mg of protein)-1.	n3-nad	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	90-113
3933890-1	1985	gamma-L-Glutamyl-L-dopa was given by intravenous infusion to eight normal subjects at doses of 12.5 and 100 micrograms min-1 kg-1.	gamma-l-glutamyl-l-dopa	0-23	CD59 molecule (CD59 blood group)	Homo sapiens	119-129
4025577-6	1985	A maternal placental blood flow of less than 200 ml X min-1 X kg fetal wt-1 produces a steady-state value of oxygen tension in the fetal ascending aorta of less than 17 mmHg, which is incompatible with normal oxygen delivery.	Oxygen	109-115	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
4025577-7	1985	A minimal value of umbilical flow providing an adequate oxygen supply to the fetal body is 87 ml X min-1 X kg fetal wt-1.	Oxygen	56-62	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
3933890-7	1985	On administration of the dipeptide at 12.5 micrograms min-1 kg-1 there were no changes in blood pressure or heart rate, but at the higher dose there was a fall in diastolic blood pressure.	Dipeptides	25-34	CD59 molecule (CD59 blood group)	Homo sapiens	54-64
3933890-5	1985	Mean urine free dopamine excretion increased by 280- and 2500-fold at infusion rates of 12.5 and 100 micrograms min-1 kg-1 respectively.	Dopamine	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	112-122
3933890-8	1985	At a dose of 12.5 micrograms min-1 kg-1 in man, there is kidney specific conversion of gludopa to dopamine.	gamma-glutamyl DOPA	87-94	CD59 molecule (CD59 blood group)	Homo sapiens	29-39
3933890-8	1985	At a dose of 12.5 micrograms min-1 kg-1 in man, there is kidney specific conversion of gludopa to dopamine.	Dopamine	98-106	CD59 molecule (CD59 blood group)	Homo sapiens	29-39
3933890-6	1985	Mean plasma free dopamine rose at both doses but the increase at 12.5 micrograms min-1 kg-1 was not to a level previously associated with systemic effects of the catecholamine.	Dopamine	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	81-91
2995048-5	1985	Release of active renin increased from 580 (SEM 170) to 650 (SEM 220) microU min-1 (100 g)-1 during infusion of doxazosin (P less than 0.05) and from 760 (SEM 100) to 1000 (SEM 340) microU min-1 (100 g)-1 during infusion of phentolamine (P less than 0.01).	Doxazosin	112-121	CD59 molecule (CD59 blood group)	Homo sapiens	77-92
4064562-8	1985	After glucose administration, alanine release was suppressed (in all subjects) from a mean value of 153 +/- 22 to 57 +/- 16 nmol min-1 100 ml-1 of forearm (P less than 0.02) whereas that of glutamine was not significantly affected (160 +/- 30 to 143 +/- 29 nmol min-1 100 ml-1 of forearm).	Glucose	6-13	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
4064562-8	1985	After glucose administration, alanine release was suppressed (in all subjects) from a mean value of 153 +/- 22 to 57 +/- 16 nmol min-1 100 ml-1 of forearm (P less than 0.02) whereas that of glutamine was not significantly affected (160 +/- 30 to 143 +/- 29 nmol min-1 100 ml-1 of forearm).	Glucose	6-13	CD59 molecule (CD59 blood group)	Homo sapiens	262-267
4064562-8	1985	After glucose administration, alanine release was suppressed (in all subjects) from a mean value of 153 +/- 22 to 57 +/- 16 nmol min-1 100 ml-1 of forearm (P less than 0.02) whereas that of glutamine was not significantly affected (160 +/- 30 to 143 +/- 29 nmol min-1 100 ml-1 of forearm).	Alanine	30-37	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
4064562-11	1985	The net amino acid balance across the forearm muscle bed was negative throughout the study but decreased from a mean value of -567 in the basal state to -300 nmol min-1 100 ml-1 of forearm after glucose administration for 60 min.	Glucose	195-202	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
2995048-7	1985	While handgrip exercise had no significant effect on active renin secretion in the saline and in the doxazosin group, it enhanced secretion from 1000 (SEM 340) to 1280 (SEM 390) microU min-1 (100 g)-1 in the phentolamine group (P less than 0.01).	Phentolamine	208-220	CD59 molecule (CD59 blood group)	Homo sapiens	185-200
3930258-7	1985	In humans the hepatic net acetate uptake from the portal vein/net acetate release into the hepatic vein, measured as mmol min-1, is linearly related to the portal vein acetate concentration (r = 0.96).	Acetates	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
3930258-7	1985	In humans the hepatic net acetate uptake from the portal vein/net acetate release into the hepatic vein, measured as mmol min-1, is linearly related to the portal vein acetate concentration (r = 0.96).	Acetates	66-73	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
3930258-7	1985	In humans the hepatic net acetate uptake from the portal vein/net acetate release into the hepatic vein, measured as mmol min-1, is linearly related to the portal vein acetate concentration (r = 0.96).	Acetates	66-73	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
3897287-7	1985	On the other hand, the fractional catabolic rate for free fatty acid was significantly lower in untreated diabetics (0.55 +/- 0.04 vs. 0.71 +/- 0.06 min-1, P less than 0.05); it increased after therapy to 0.80 +/- 0.09 min-1, P less than 0.05, and was inversely correlated with fasting glucose (r = -0.52, P less than 0.01).	Fatty Acids, Nonesterified	53-68	CD59 molecule (CD59 blood group)	Homo sapiens	149-154
4044104-9	1985	However, in using a 2 mM lactate level as a criterion, the LT during the caffeine trial (2.13 +/- 0.22 l X min-1) was significantly (P less than 0.05) lower than during the control trial (2.71 +/- 0.17 l X min-1).	Caffeine	73-81	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
4044104-9	1985	However, in using a 2 mM lactate level as a criterion, the LT during the caffeine trial (2.13 +/- 0.22 l X min-1) was significantly (P less than 0.05) lower than during the control trial (2.71 +/- 0.17 l X min-1).	Caffeine	73-81	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
3897287-7	1985	On the other hand, the fractional catabolic rate for free fatty acid was significantly lower in untreated diabetics (0.55 +/- 0.04 vs. 0.71 +/- 0.06 min-1, P less than 0.05); it increased after therapy to 0.80 +/- 0.09 min-1, P less than 0.05, and was inversely correlated with fasting glucose (r = -0.52, P less than 0.01).	Fatty Acids, Nonesterified	53-68	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
3161078-2	1985	The kcat/Km values for the individual homogeneous class I isozymes are generally in the range from 2.0 to 10 mM-1 X min-1, slightly lower than those obtained for ethanol oxidation, 16-66 mM-1 X min-1, but considerably higher than those obtained for ethylene glycol oxidation, 0.23-1.5 mM-1 X min-1.	Ethylene Glycol	249-264	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
3929551-5	1985	In Group 1 etomidate infusion of 30 micrograms kg-1 min-1 was used throughout the anaesthesia, and CBF and CMRO2 were measured twice.	Etomidate	11-20	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
3929551-8	1985	In Group 2 the etomidate infusion was increased from 30 to 60 micrograms kg-1 min-1 after the first study and a significant fall in CMRO2 from 2.52 +/- 0.56 to 1.76 +/- 0.40 ml O2 100 g-1 min-1 was found.	Etomidate	15-24	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
3929551-8	1985	In Group 2 the etomidate infusion was increased from 30 to 60 micrograms kg-1 min-1 after the first study and a significant fall in CMRO2 from 2.52 +/- 0.56 to 1.76 +/- 0.40 ml O2 100 g-1 min-1 was found.	Etomidate	15-24	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
4039766-4	1985	Maximal oxygen uptake increased significantly in both groups: 11 mL O2/kg/min-1 or 30% in the sedentary group and 6 mL O2/kg/min-1 or 13% in the monozygotic twins.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
4039766-4	1985	Maximal oxygen uptake increased significantly in both groups: 11 mL O2/kg/min-1 or 30% in the sedentary group and 6 mL O2/kg/min-1 or 13% in the monozygotic twins.	Oxygen	68-70	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
4039766-4	1985	Maximal oxygen uptake increased significantly in both groups: 11 mL O2/kg/min-1 or 30% in the sedentary group and 6 mL O2/kg/min-1 or 13% in the monozygotic twins.	Oxygen	119-121	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
2860493-3	1985	The average creatinine clearance was 83.9 +/- 16.5 ml/min/1.73 m2 or 74.3% of that in healthy controls with two kidneys; it was a value similar to that reported 3 to 6 months postnephrectomy in kidney donors.	Creatinine	12-22	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
2988347-3	1985	At a perfusion rate of 14 nl/min, addition of 10(-3) M amiloride to artificial early proximal tubular fluid reduced bicarbonate absorption from 103 +/- 7 to 81 +/- 5 pmol mm-1 X min-1 and volume absorption from 2.03 +/- 0.15 to 1.57 +/- 0.06 nl X mm-1 X min-1.	Amiloride	55-64	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
2988347-3	1985	At a perfusion rate of 14 nl/min, addition of 10(-3) M amiloride to artificial early proximal tubular fluid reduced bicarbonate absorption from 103 +/- 7 to 81 +/- 5 pmol mm-1 X min-1 and volume absorption from 2.03 +/- 0.15 to 1.57 +/- 0.06 nl X mm-1 X min-1.	Amiloride	55-64	CD59 molecule (CD59 blood group)	Homo sapiens	254-259
2988347-6	1985	At a perfusion rate of 41 nl/min, 10(-3) M amiloride reduced bicarbonate absorption from 179 +/- 8 to 114 +/- 9 pmol X mm-1 X min-1, a significantly greater inhibition than that seen in tubules perfused at 14 nl/min.	Amiloride	43-52	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
3890909-4	1985	Seven of the patients received a continuous infusion of etomidate, increasing in five equal steps from 0.01 mg kg-1 min-1 to 0.05 mg kg-1 min-1 over a period of 50 min.	Etomidate	56-65	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
3890909-4	1985	Seven of the patients received a continuous infusion of etomidate, increasing in five equal steps from 0.01 mg kg-1 min-1 to 0.05 mg kg-1 min-1 over a period of 50 min.	Etomidate	56-65	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
4004905-8	1985	The other enzymatic rate constants are 0.016 min-1 for C(+)P(-), 0.74 min-1 for C(-)P(+) and 0.028 min-1 for C(-)P(-).	Carbon	55-56	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
4004905-8	1985	The other enzymatic rate constants are 0.016 min-1 for C(+)P(-), 0.74 min-1 for C(-)P(+) and 0.028 min-1 for C(-)P(-).	Carbon	55-56	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
4004905-8	1985	The other enzymatic rate constants are 0.016 min-1 for C(+)P(-), 0.74 min-1 for C(-)P(+) and 0.028 min-1 for C(-)P(-).	Carbon	55-56	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
4005096-1	1985	The cardiovascular effects of an infusion of chlormethiazole 30-40 ml min-1 were studied in six patients following an extradural injection of 2% lignocaine.	Chlormethiazole	45-60	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
4029126-1	1985	Six volunteers were subjected to an infusion of etomidate designed to generate linearly increasing plasma concentrations with a slope of 0.05 microgram ml-1 min-1.	Etomidate	48-57	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
4029127-1	1985	Etomidate was administered to six healthy volunteers by microprocessor controlled infusions, to generate three cycles of linearly increasing plasma levels, with an anticipated slope of 0.05 microgram ml-1 min-1.	Etomidate	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
3872872-5	1985	The average net, steady-state rate of fluorodeoxyglucose (KD) accumulation in normal regions of the four patients was 0.025 ml g-1 min-1.	Fluorodeoxyglucose F18	38-56	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
3872872-14	1985	The average glucose metabolic rates of the 365 normal regions, in which gray matter regions prevailed by 20:1, was 32 mumol 100 g-1 min-1.	Glucose	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
3872872-15	1985	The average glucose phosphorylation rate in white matter was 20 mumol 100 g-1 min-1 with a lumped constant of 0.45.	Glucose	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
3872872-16	1985	In the recently infarcted areas, the lumped constants varied from 0.37 to 2.83, corresponding to glucose metabolic rates varying from 2 to 18 mumol 100 g-1 min-1.	Glucose	97-104	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
4019794-6	1985	The in vitro release rate of theophylline from freshly prepared formulations was, however, higher (4.8 mg min-1) from aminophylline suppositories relative to those containing theophylline (2.9 mg min-1).	Theophylline	29-41	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
4019794-6	1985	The in vitro release rate of theophylline from freshly prepared formulations was, however, higher (4.8 mg min-1) from aminophylline suppositories relative to those containing theophylline (2.9 mg min-1).	Aminophylline	118-131	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
4019794-9	1985	The release rate of aminophylline suppositories tested after 1-year storage at room temperature dropped from 4.8 to 0.5 mg min-1.	Aminophylline	20-33	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
4020703-1	1985	Intravenous injection of 2 mg naloxone produced a rapid and pronounced rise of blood flow (6.3 +/- 5.0 to 67.0 +/- 15.1 ml min-1 100 ml-1) and skin temperature (28.3 +/- 3.0 to 32.4 +/- 1.2 degrees C) in the finger and hand of seven of ten normal volunteers.	Naloxone	30-38	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
2992572-4	1985	At pH 7.0, ghosts loaded with 100 mM ascorbic acid reduce 60 microM cytochrome c at a rate of 0.035 +/- 0.010 mu equiv min-1 (mg of protein)-1 and 200 microM ferricyanide at a rate of 2.3 +/- 0.3 mu equiv min-1 (mg of protein)-1.	Ascorbic Acid	37-50	CD59 molecule (CD59 blood group)	Homo sapiens	119-142
2992572-4	1985	At pH 7.0, ghosts loaded with 100 mM ascorbic acid reduce 60 microM cytochrome c at a rate of 0.035 +/- 0.010 mu equiv min-1 (mg of protein)-1 and 200 microM ferricyanide at a rate of 2.3 +/- 0.3 mu equiv min-1 (mg of protein)-1.	Ascorbic Acid	37-50	CD59 molecule (CD59 blood group)	Homo sapiens	205-228
2992572-5	1985	The rate of cytochrome c reduction is accelerated to 0.105 +/- 0.021 mu equiv min-1 (mg of protein)-1 when cytochrome c is pretreated with equimolar ferrocyanide.	hexacyanoferrate II	149-161	CD59 molecule (CD59 blood group)	Homo sapiens	78-101
3922213-1	1985	Lower renal plasma clearances of selenium (CSe 0.1-0.2 ml min-1), indicating excretion of a smaller proportion of Se presented to the kidneys, were found in New Zealand (NZ) residents with low plasma Se ((Se)p 50-70 ng ml-1) on customary intakes below 30 micrograms d-1 Se.	Selenium	33-41	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
3158254-9	1985	min-1 during halothane or isoflurane anesthesia; the requirements during balanced anesthesia were 9.3 +/- 0.8 micrograms .	Halothane	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
3994013-5	1985	min-1) affect the catecholamine stress response to surgery differently.	Catecholamines	18-31	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
3994879-5	1985	There was a mean increase in heart rate of 5 beat min-1 during anaesthesia although the maximum values reached 200 beat min-1 in children, and 150 beat min-1 in adults who received fazadinium and 140 beat min-1 in adults who did not.	fazadinium	181-191	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
3892348-4	1985	A 1 microgram/kg-1 min-1 intravenous infusion of nimodipine in patients during EC-IC bypass operation led to a 16% dilatation of pial arteries; the solvent remained without effect.	Nimodipine	49-59	CD59 molecule (CD59 blood group)	Homo sapiens	19-24
3158147-6	1985	CO2 production was 2.13 ml kg-1 min-1 (interquartile range 2.09-2.23).	Carbon Dioxide	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	32-37
3158147-7	1985	A fresh gas flow rate of about 30 ml kg-1 min-1 was required for the elimination of CO2 produced when using the Venturi system for inhalation anaesthesia.	Carbon Dioxide	84-87	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
3922197-8	1985	Carbon dioxide output was 173 ml X min-1 (STPD) in the adults and 82 +/- 13 ml X min-1 (STPD) in the children.	Carbon Dioxide	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
2408698-5	1985	In subendocardial strips of ventricular septum from 5 patients with HOCM paced at 60 min-1, both (-)-verapamil and (+)-verapamil caused cardiodepression.	Verapamil	97-110	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
2408698-5	1985	In subendocardial strips of ventricular septum from 5 patients with HOCM paced at 60 min-1, both (-)-verapamil and (+)-verapamil caused cardiodepression.	Verapamil	115-128	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
4007074-2	1985	The DHPR activity was higher in the retina [120.56 +/- 12.46 nmol NADH oxidized min-1 (mg soluble protein)-1] than in the ciliary body--iris [46.10 +/- 7.46 nmol NADH oxidized min-1 (mg soluble protein)-1] and lens [2.79 +/- 0.15 nmol NADH oxidized min-1 (mg soluble protein)-1].	NAD	66-70	CD59 molecule (CD59 blood group)	Homo sapiens	80-108
3982389-1	1985	Arsenite is a quasi-irreversible inhibitor of human serum butyrylcholinesterase with a dissociation constant of 0.129 mM at pH 7.4, 25 degrees, 0.067 M phosphate, mu = 0.17 M. The inhibition process is second order with a rate constant of 340 M-1 min-1.	arsenite	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	247-252
3982389-2	1985	The first order rate of dissociation, 0.044 min-1, is unaffected by fluoride but is decreased by substrate.	Fluorides	68-76	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
3987216-6	1985	For volunteers with a creatinine clearance of less than 15 mL/min/1.73 sq m, the mean half-life was 15.6 hours.	Creatinine	22-32	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
3987216-7	1985	For subjects with a creatinine clearance of 31-60 mL/min/1.73 sq m, the mean half-life was 11.9 hours.	Creatinine	20-30	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
3874774-3	1985	Ten patients received phentolamine (about 25 micrograms kg-1 min-1) and ten patients received urapidil (about 100 micrograms kg-1 min-1) to return arterial blood pressure to control levels.	urapidil	94-102	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
2412213-2	1985	GRP10 was catabolized by gastric muscle peptidases (specific activity 1.8 nmol min-1 mg-1 protein) by hydrolysis of the His8-Leu9 bond and catabolism was inhibited by phosphoramidon (I50 approx.	phosphoramidon	167-181	CD59 molecule (CD59 blood group)	Homo sapiens	79-89
3886645-3	1985	Diethyl pyrocarbonate inactivated the potential fibrinogen-clotting activity of prothrombin with a second-order rate constant of 70 M-1 min-1 at pH 6.0 and 25 degrees C. The difference spectrum of the modified protein had a maximum absorption at 240 nm which is characteristic of N-carbethoxyhistidine.	Diethyl Pyrocarbonate	0-21	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
2857109-4	1985	Inhibition of proton transport was correlated with inhibition of adenosine triphosphate hydrolysis, both demonstrating an inhibition rate of 2% min-1.	Adenosine Triphosphate	65-87	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
3987210-7	1985	At a steady state lactate concentration of 25.5 mM, maternal to foetal flux rate was 30.1 mumol min-1 and foetal to maternal flux rate was 34.0 mumol min-1, in agreement with measurements reported by other workers.	Lactic Acid	18-25	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
3985427-5	1985	The DPHE was given by the amount of ICG perfused in mg X min-1 divided by the arterial concentration of ICG less the concentration of ICG in the hepatic vein (in mg X 1(-1)).	D-phenylalanine	4-8	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
2859043-5	1985	Ambulatory monitoring of HR showed that subjects spent 13% of their waking day at heart rates below 50 beats min-1 while on propranolol, compared with 1% on placebo and 20% on atenolol and betaxolol.	Propranolol	124-135	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
4039416-4	1985	The rate constants ranged from 7.9 to 0.1 min-1 in the concentration range 0.04-25 mM of 2DG.	Deoxyglucose	89-92	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
4061064-4	1985	The activity in normal secretory endometrium was 15.3 +/- 1.27 pmol cholesteryl ester formed per mg protein-1 per min-1, whereas 3 out of 4 endometrial cancers had 3-7-fold higher ACAT activity.	Cholesterol Esters	68-85	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
2858217-6	1985	For diazepam, propoxyphene produced a small and statistically insignificant prolongation of elimination half-life (43 vs 38 h) and reduction of total clearance (0.41 vs 0.47 ml min-1 kg-1).	Dextropropoxyphene	14-26	CD59 molecule (CD59 blood group)	Homo sapiens	177-187
2858217-7	1985	Propoxyphene significantly prolonged alprazolam half-life (18 vs 12 h, P less than 0.005) and reduced total clearance (0.8 vs 1.3 ml min-1 kg-1, P less than 0.005).	Dextropropoxyphene	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	133-143
3930009-2	1985	Under these conditions, the dissociation constant Kd of the 1:1 complex formed by beta-CD and soman and the rate constant k2 for the phosphonylation of beta-CD by soman are (0.53 +/- 0.05)mM and (5.9 +/- 0.6) X 10(-2) min-1 respectively.	betadex	82-89	CD59 molecule (CD59 blood group)	Homo sapiens	218-223
3930009-2	1985	Under these conditions, the dissociation constant Kd of the 1:1 complex formed by beta-CD and soman and the rate constant k2 for the phosphonylation of beta-CD by soman are (0.53 +/- 0.05)mM and (5.9 +/- 0.6) X 10(-2) min-1 respectively.	betadex	152-159	CD59 molecule (CD59 blood group)	Homo sapiens	218-223
3996046-4	1985	Oxygen consumption per cell was 0.244 +/- 0.02 mumol min-1 per 10(8) cells and the enthalpy change was -836 kJ/mol O2.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
3987548-12	1985	In the long term treated patients with glomerular filtration rates greater than 15 ml/min/1.73m2 all but 1 showed an improved renal function by 26 +/- 19% (n = 5) after initiation of felodipine therapy.	Felodipine	183-193	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
3930241-4	1985	Compared to the smokeless trials, the passive inhalation of smoke significantly reduced maximal oxygen uptake by 0.25 l X min-1 and time to exhaustion by 2.1 min.	Oxygen	96-102	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
4006961-6	1985	Nifedipine increased free fatty acid (FFA) extraction during pacing (from 1.5 +/- 12.9% to 17.4 +/- 13.1%, P less than 0.02) and uptake (from 1.8 +/- 8.5 to 11.1 +/- 10.6 mu mol min-1, P less than 0.05).	Nifedipine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
4007028-3	1985	Digoxin clearance in chronic heart failure proved to be significantly lower than in atrial fibrillation (48 +/- 21 vs 71 +/- 36 ml X min-1, p less than 0.05), and Cdig/Ccreat was similarly reduced at 0.73 +/- 0.15 compared to 1.09 +/- 0.27 (p less than 0.005).	Digoxin	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
4039258-1	1985	The effect of a progressively increasing work rate (15 W X min-1) up to exhaustion on the time course of O2 uptake (VO2), ventilation (VE) and heart rate (HR) has been studied in weight lifters (WL) in comparison to endurance cyclists (Cycl) and sedentary controls (Sed).	Oxygen	105-107	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
4043042-4	1985	When the same exercise was performed after arterial infusion of phentolamine, forearm blood flow increased steadily to near maximal levels of 38.7 +/- 1.4 ml X min(-1) X 100 ml(-1).	Phentolamine	64-76	CD59 molecule (CD59 blood group)	Homo sapiens	160-173
4054206-2	1985	Coadministration of phenytoin caused a significant reduction in the elimination half-life of digoxin from 33.9 to 23.7 h and a diminution in AUC0-48 from 31.6 to 24.4 ng X ml-1 X h. Renal digoxin clearance was not significantly altered from 135.7 to 120.3 ml X min-1.	Phenytoin	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	261-266
4054206-3	1985	Assuming no change in beta-acetyldigoxin absorption, the in decrease time-course the serum digoxin concentration was due to a significantly increased total digoxin clearance from 258.6 to 328.3 ml X min-1.	Digoxin	91-98	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
4076330-5	1985	The mean metabolic clearance of piretanide was 107.7 +/- 47.6 ml/min/1.73 m2 body surface area and was the same as that reported for healthy subjects.	piretanide	32-42	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
4076330-6	1985	The renal clearance of piretanide ranged from 3.33 to 43.9 ml/min/1.73 m2 body surface area and very closely correlated with the creatinine clearance (p less than 0.01).	piretanide	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
3997374-5	1985	CIT clearance correlated well with GFR above 50 ml/min/1.73 m2.	Citric Acid	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
3997374-6	1985	At lower levels, percent tubular reabsorption of CIT decreased rapidly, reaching levels between 17% and 41% at GFR less than 10 ml/min/1.73 m2; this disproportionate fall might be related to reduced renal CIT utilization at a relatively early stage of renal insufficiency.	Citric Acid	49-52	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
4019017-6	1985	Maximal oxygen consumption (VO2 max, m10(2)/kg X min-1) predicted from the Bruce Test increased by 0.08 +/- 7, 9 +/- 12 and 12 +/- 9 percent in groups C, D and P, respectively.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
3968295-16	1985	min-1 a significant increase in stroke volume, mixed venous oxygen tension and decrease in right atrial pressure and systemic vascular resistance was also observed.	Oxygen	60-66	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
3968295-19	1985	min-1 a significant increase in pulse rate, mean arterial blood pressure mean pulmonary blood pressure, right ventricular stroke work index, right atrial pressure and pulmonary arterial occlusion pressure and decrease in arterial oxygen tension was also observed.	Oxygen	230-236	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
3880560-9	1985	In addition, SI in the older group was diminished 63% (2.4 vs. 6.5; 10(-4) min-1/microU/ml; P less than 0.001) and was unrelated to differences in body fat.	Silicon	13-15	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
3880820-5	1985	Currently the group mean (+/- SE) serum creatinine concentration is 1.22 +/- 0.11 mg/dl and creatinine clearance is 69.3 +/- 4.79 ml/min/1.73 m2.	Creatinine	92-102	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
3830285-2	1985	Oxygen consumption (ml min-1 m-2) increased from 149 to 224 during C, from 160 to 196 during HL, from 154 to 178 during HP, and from 166 to 187 during HL.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	23-28
4022111-3	1985	Hexanal is rapidly autoxidized in mixture with nonlipidic substrates even at 25 degrees C. The formation of peroxides follows the kinetics of a first order reaction with respect to hexanal (k1 about 10(-5) min-1), and is higher in mixture with casein or lysine-impregnated cellulose than with cellulose.	Peroxides	108-117	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
4022111-3	1985	Hexanal is rapidly autoxidized in mixture with nonlipidic substrates even at 25 degrees C. The formation of peroxides follows the kinetics of a first order reaction with respect to hexanal (k1 about 10(-5) min-1), and is higher in mixture with casein or lysine-impregnated cellulose than with cellulose.	Lysine	254-260	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
4022111-3	1985	Hexanal is rapidly autoxidized in mixture with nonlipidic substrates even at 25 degrees C. The formation of peroxides follows the kinetics of a first order reaction with respect to hexanal (k1 about 10(-5) min-1), and is higher in mixture with casein or lysine-impregnated cellulose than with cellulose.	Cellulose	273-282	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
4022111-3	1985	Hexanal is rapidly autoxidized in mixture with nonlipidic substrates even at 25 degrees C. The formation of peroxides follows the kinetics of a first order reaction with respect to hexanal (k1 about 10(-5) min-1), and is higher in mixture with casein or lysine-impregnated cellulose than with cellulose.	Cellulose	293-302	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
4022111-4	1985	In mixtures containing pure hexanal, peroxides are decomposed more rapidly after second-order reaction with respect to peroxides (k2 about 10(-3) mmol X kg-1 X min-1) while only slowly by the first-order reaction (k3 about 10(-5) min-1).	Peroxides	37-46	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
4022111-4	1985	In mixtures containing pure hexanal, peroxides are decomposed more rapidly after second-order reaction with respect to peroxides (k2 about 10(-3) mmol X kg-1 X min-1) while only slowly by the first-order reaction (k3 about 10(-5) min-1).	Peroxides	37-46	CD59 molecule (CD59 blood group)	Homo sapiens	230-235
4022111-4	1985	In mixtures containing pure hexanal, peroxides are decomposed more rapidly after second-order reaction with respect to peroxides (k2 about 10(-3) mmol X kg-1 X min-1) while only slowly by the first-order reaction (k3 about 10(-5) min-1).	Peroxides	119-128	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
4022111-4	1985	In mixtures containing pure hexanal, peroxides are decomposed more rapidly after second-order reaction with respect to peroxides (k2 about 10(-3) mmol X kg-1 X min-1) while only slowly by the first-order reaction (k3 about 10(-5) min-1).	Peroxides	119-128	CD59 molecule (CD59 blood group)	Homo sapiens	230-235
4022111-5	1985	In presence of small amounts of hexanoic acid the rate of second-order peroxide decomposition remained unaffected while the rate of the first-order peroxide decomposition increased by 4 orders (k3 about 10(-1) min-1).	hexanoic acid	32-45	CD59 molecule (CD59 blood group)	Homo sapiens	210-215
4022111-5	1985	In presence of small amounts of hexanoic acid the rate of second-order peroxide decomposition remained unaffected while the rate of the first-order peroxide decomposition increased by 4 orders (k3 about 10(-1) min-1).	Peroxides	148-156	CD59 molecule (CD59 blood group)	Homo sapiens	210-215
6511790-4	1984	The activity of the purified enzyme toward palmitoyl lysophosphatidylcholine is 2.5 mumol min-1 mg-1 and the pH optimum is 7.0.	We 201	43-76	CD59 molecule (CD59 blood group)	Homo sapiens	90-100
6441433-7	1984	min-1 of etomidate provided good sedation and analgesia, without clinically significant respiratory depression.	Etomidate	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6498049-4	1984	The plasma clearance of thiopentone was significantly increased from 3.7 +/- 0.9 ml min-1 kg-1 in the controls to 5.4 +/- 2.2 ml min-1 kg-1 in the patients with chronic alcoholism.	Thiopental	24-35	CD59 molecule (CD59 blood group)	Homo sapiens	84-94
6397223-4	1984	The class II isozyme catalyzes the oxidation of a variety of alcohols with Km values ranging from 7 microM to 560 mM and with kcat values from 32 min-1 to 600 min-1 and demonstrates a preference for hydrophobic substrates.	Alcohols	61-69	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
6397223-4	1984	The class II isozyme catalyzes the oxidation of a variety of alcohols with Km values ranging from 7 microM to 560 mM and with kcat values from 32 min-1 to 600 min-1 and demonstrates a preference for hydrophobic substrates.	Alcohols	61-69	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
6517816-6	1984	HR was increased 48% (53 b X min-1) by atropine pre-acclimation (p less than 0.01).	Atropine	39-47	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
6517816-7	1984	Post-acclimation, atropine reduced (p less than 0.01) Msw 33% (100 g X m-2 X h-1) and increased (p less than 0.01) HR 63% (62 b X min-1) compared to saline exposures.	Atropine	18-26	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
6517816-8	1984	The change in Tre X min-1 (delta Tre/delta t) was lower (p less than 0.05) in atropine-injected subjects following heat acclimation, and their worktime was improved by an average of 23.5 min (p = 0.08).	Atropine	78-86	CD59 molecule (CD59 blood group)	Homo sapiens	20-25
6498049-4	1984	The plasma clearance of thiopentone was significantly increased from 3.7 +/- 0.9 ml min-1 kg-1 in the controls to 5.4 +/- 2.2 ml min-1 kg-1 in the patients with chronic alcoholism.	Thiopental	24-35	CD59 molecule (CD59 blood group)	Homo sapiens	129-139
6542834-10	1984	In the subgroup of seven subjects in whom glucose values decreased with water intake, the mean rate of glycogen degradation was significantly lower (P less than 0.05) with the ingestion of glucose (1.3 +/- 0.4 mmol kg d.w.-1 min-1) as compared to fructose (2.1 +/- 0.5 mmol kg d.w.-1 min-1) or water (2.3 +/- 0.5 mmol kg d.w.-1 min-1).	Glucose	189-196	CD59 molecule (CD59 blood group)	Homo sapiens	284-289
6542834-10	1984	In the subgroup of seven subjects in whom glucose values decreased with water intake, the mean rate of glycogen degradation was significantly lower (P less than 0.05) with the ingestion of glucose (1.3 +/- 0.4 mmol kg d.w.-1 min-1) as compared to fructose (2.1 +/- 0.5 mmol kg d.w.-1 min-1) or water (2.3 +/- 0.5 mmol kg d.w.-1 min-1).	Glycogen	103-111	CD59 molecule (CD59 blood group)	Homo sapiens	225-230
6098479-3	1984	We obtained evidence suggesting that active calcium efflux by erythrocytes from patients with FBH (85.7 +/- 4.5 mumol 1(-1) min-1) is higher (P less than 0.005) than that by erythrocytes from control subjects (78.6 +/- 4.1 mumol 1(-1) min-1) or from patients with primary hyperparathyroidism (77.5 +/- 5.2 mumol 1(-1) min-1, P less than 0.05).	Calcium	44-51	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
6542834-10	1984	In the subgroup of seven subjects in whom glucose values decreased with water intake, the mean rate of glycogen degradation was significantly lower (P less than 0.05) with the ingestion of glucose (1.3 +/- 0.4 mmol kg d.w.-1 min-1) as compared to fructose (2.1 +/- 0.5 mmol kg d.w.-1 min-1) or water (2.3 +/- 0.5 mmol kg d.w.-1 min-1).	Glycogen	103-111	CD59 molecule (CD59 blood group)	Homo sapiens	284-289
6542834-10	1984	In the subgroup of seven subjects in whom glucose values decreased with water intake, the mean rate of glycogen degradation was significantly lower (P less than 0.05) with the ingestion of glucose (1.3 +/- 0.4 mmol kg d.w.-1 min-1) as compared to fructose (2.1 +/- 0.5 mmol kg d.w.-1 min-1) or water (2.3 +/- 0.5 mmol kg d.w.-1 min-1).	Glycogen	103-111	CD59 molecule (CD59 blood group)	Homo sapiens	284-289
6542834-10	1984	In the subgroup of seven subjects in whom glucose values decreased with water intake, the mean rate of glycogen degradation was significantly lower (P less than 0.05) with the ingestion of glucose (1.3 +/- 0.4 mmol kg d.w.-1 min-1) as compared to fructose (2.1 +/- 0.5 mmol kg d.w.-1 min-1) or water (2.3 +/- 0.5 mmol kg d.w.-1 min-1).	Glucose	189-196	CD59 molecule (CD59 blood group)	Homo sapiens	225-230
6542834-10	1984	In the subgroup of seven subjects in whom glucose values decreased with water intake, the mean rate of glycogen degradation was significantly lower (P less than 0.05) with the ingestion of glucose (1.3 +/- 0.4 mmol kg d.w.-1 min-1) as compared to fructose (2.1 +/- 0.5 mmol kg d.w.-1 min-1) or water (2.3 +/- 0.5 mmol kg d.w.-1 min-1).	Glucose	189-196	CD59 molecule (CD59 blood group)	Homo sapiens	284-289
6098479-3	1984	We obtained evidence suggesting that active calcium efflux by erythrocytes from patients with FBH (85.7 +/- 4.5 mumol 1(-1) min-1) is higher (P less than 0.005) than that by erythrocytes from control subjects (78.6 +/- 4.1 mumol 1(-1) min-1) or from patients with primary hyperparathyroidism (77.5 +/- 5.2 mumol 1(-1) min-1, P less than 0.05).	Calcium	44-51	CD59 molecule (CD59 blood group)	Homo sapiens	235-240
6098479-3	1984	We obtained evidence suggesting that active calcium efflux by erythrocytes from patients with FBH (85.7 +/- 4.5 mumol 1(-1) min-1) is higher (P less than 0.005) than that by erythrocytes from control subjects (78.6 +/- 4.1 mumol 1(-1) min-1) or from patients with primary hyperparathyroidism (77.5 +/- 5.2 mumol 1(-1) min-1, P less than 0.05).	Calcium	44-51	CD59 molecule (CD59 blood group)	Homo sapiens	235-240
6536519-4	1984	For patients aged 20-40 years (young group), the ED50 values for Althesin (as alphaxalone) and methohexitone were 14.6 micrograms kg-1 min-1 and 59.9 micrograms kg-1 min-1.	Methohexital	95-108	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
6441723-6	1984	After 3 days of ammonium chloride loading, ammonium excretion averaged 54.7 +/- 4.2 in group A, 54.4 +/- 4.3 in group B and 64.3 +/- 5.5 mumol min-1 in group C. Values obtained in the first two groups were significantly lower than that achieved by control subjects (76.4 +/- 14.9 mumol min-1).	Ammonium Chloride	16-33	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
6441723-6	1984	After 3 days of ammonium chloride loading, ammonium excretion averaged 54.7 +/- 4.2 in group A, 54.4 +/- 4.3 in group B and 64.3 +/- 5.5 mumol min-1 in group C. Values obtained in the first two groups were significantly lower than that achieved by control subjects (76.4 +/- 14.9 mumol min-1).	Ammonium Chloride	16-33	CD59 molecule (CD59 blood group)	Homo sapiens	286-291
6441723-6	1984	After 3 days of ammonium chloride loading, ammonium excretion averaged 54.7 +/- 4.2 in group A, 54.4 +/- 4.3 in group B and 64.3 +/- 5.5 mumol min-1 in group C. Values obtained in the first two groups were significantly lower than that achieved by control subjects (76.4 +/- 14.9 mumol min-1).	Ammonium Compounds	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
6536519-6	1984	For patients aged 55-80 years (old group), the ED50 values for Althesin and methohexitone were 11.0 micrograms kg-1 min-1 and 44.2 micrograms kg-1 m in-1, while the corresponding ED95 values were 16.4 micrograms kg-1 min-1 and 76.2 micrograms kg-1 min-1.	Methohexital	76-89	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
6536519-6	1984	For patients aged 55-80 years (old group), the ED50 values for Althesin and methohexitone were 11.0 micrograms kg-1 min-1 and 44.2 micrograms kg-1 m in-1, while the corresponding ED95 values were 16.4 micrograms kg-1 min-1 and 76.2 micrograms kg-1 min-1.	Methohexital	76-89	CD59 molecule (CD59 blood group)	Homo sapiens	217-222
6536519-6	1984	For patients aged 55-80 years (old group), the ED50 values for Althesin and methohexitone were 11.0 micrograms kg-1 min-1 and 44.2 micrograms kg-1 m in-1, while the corresponding ED95 values were 16.4 micrograms kg-1 min-1 and 76.2 micrograms kg-1 min-1.	Methohexital	76-89	CD59 molecule (CD59 blood group)	Homo sapiens	217-222
6520066-4	1984	In five patients with a creatinine clearance greater than 1 ml min-1 kg-1, a mean plasma elimination half-life of 7.8 +/- 2.8 h was calculated.	Creatinine	24-34	CD59 molecule (CD59 blood group)	Homo sapiens	63-73
6085236-4	1984	Low-dose dopamine infusion less than 3 micrograms kg-1 min-1 is investigated in ten other patients.	Dopamine	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
6439182-5	1984	Alveolar PCO2 on the summit was 7.5 mm Hg, the arterial pH and PO2 were calculated to be over 7.7 and less than 30 mm Hg, respectively, and maximum oxygen uptake was about 1 L X min-1.	Oxygen	148-154	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
6541974-4	1984	In eight subjects given PGE1 (0.2 microgram X kg-1 X min-1, iv), blood pressure fell, whereas both heart rate and cardiac output rose.	Alprostadil	24-28	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
6242816-2	1984	At an insulin infusion rate of 1 mU/kg/min, insulin mediated glucose disposal was significantly greater (p less than 0.02) following delivery (1.194 +/- 0.138 mmol/m2/min) than in pregnancy (0.761 +/- 0.072 mmol/m2/min) and the rate of decline in insulin mediated glucose disposal, at the end of the insulin infusion, was significantly greater (p less than 0.02) following delivery (24.78 +/- 4.22 mumol/m2/min2) than in pregnancy (15.17 +/- 2.00 mumol/m2/min2).	Glucose	61-68	CD59 molecule (CD59 blood group)	Homo sapiens	407-411
6242816-2	1984	At an insulin infusion rate of 1 mU/kg/min, insulin mediated glucose disposal was significantly greater (p less than 0.02) following delivery (1.194 +/- 0.138 mmol/m2/min) than in pregnancy (0.761 +/- 0.072 mmol/m2/min) and the rate of decline in insulin mediated glucose disposal, at the end of the insulin infusion, was significantly greater (p less than 0.02) following delivery (24.78 +/- 4.22 mumol/m2/min2) than in pregnancy (15.17 +/- 2.00 mumol/m2/min2).	Glucose	61-68	CD59 molecule (CD59 blood group)	Homo sapiens	456-460
6391994-6	1984	Glucose utilization was 12.7 +/- 1.4, 18.2 +/- 0.7 and 22.1 +/- 3.4 mumol X kg-1 X min-1 before treatment in the diabetic subjects, and 11.8 +/- 1.7, 20.9 +/- 3.3 and 30.1 +/- 3.6 after treatment.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
6391994-8	1984	The pre-treatment metabolic clearance rate of glucose in all diabetic studies with insulin levels greater than 30 mU/l was 2.6 +/- 0.4 and rose to 3.9 +/- 0.5 ml X kg-1 X min-1 following insulin therapy.	Glucose	46-53	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
6386947-8	1984	min-1) reduced plasma leucine levels and flux similarly in both age groups.	Leucine	22-29	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6496394-5	1984	min-1) on power output (W), which reflects the rate of increase in energy expended relative to increases in external work performed, did not differ significantly between the fed and fasting conditions for either group, but the mean (+/- SEM) intercept was significantly higher for the normal, but not the obese men, in the fed than the fasting state (599 +/- 53 versus 497 +/- 47 ml O2 .	Oxygen	383-385	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6440941-3	1984	Ketone body release into blood (UA + UB) in diabetic subjects was threefold higher than normal (mean +/- SD, 208 +/- 118 versus 81 +/- 66 mumol min-1 m-2) and in obese subjects the rate increased on starvation from 171 +/- 70 to 569 +/- 286 mumol min-1 m-2.	Ketones	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
6440941-3	1984	Ketone body release into blood (UA + UB) in diabetic subjects was threefold higher than normal (mean +/- SD, 208 +/- 118 versus 81 +/- 66 mumol min-1 m-2) and in obese subjects the rate increased on starvation from 171 +/- 70 to 569 +/- 286 mumol min-1 m-2.	Ketones	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	247-252
6440941-8	1984	However, in diabetics, FCRA was 0.074 +/- 0.044 and FCRB was 0.050 +/- 0.034 min-1 and both were lower than normal.	fcrb	52-56	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
6594236-3	1984	The renal clearance (280.03 +/- 24.34 ml/min/1.73 m2) of imipenem was found to account for 69.2% of the corresponding plasma imipenem clearance (404.89 +/- 24.83 ml/min/1.73 m2).	Imipenem	57-65	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
6505989-7	1984	The mean slope of the relationship between KCO and oxygen consumption (VO2) was steeper in women than in men (mean slopes 0.627 and 0.348 mmol min-1 kPa-1 l-1 per 1 min-1 respectively), and the same was true for the relationship between KCO and work rate.	Oxygen	51-57	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
6507368-2	1984	A unit (U) of enzyme activity is the release of one n-mol of 7-amino-4-fluoromethylcoumarin (AFC) from BZ-val-lys-lys-arg-MNA min-1 ml-1.	7-amino-4-fluoromethylcoumarin	61-91	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
6333210-4	1984	In unstimulated cells, incorporation of methyl-3H into phospholipid was 0.60 +/- 0.06 pmol min-1 mg protein in neutrophil membrane, 0.84 +/- 0.075 in unseparated lymphocytes, 1.23 +/- 0.17 in T lymphocytes, and 0.71 +/- 0.085 in non-T lymphocytes (mean +/- SE).	methyl-3h	40-49	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
6333210-4	1984	In unstimulated cells, incorporation of methyl-3H into phospholipid was 0.60 +/- 0.06 pmol min-1 mg protein in neutrophil membrane, 0.84 +/- 0.075 in unseparated lymphocytes, 1.23 +/- 0.17 in T lymphocytes, and 0.71 +/- 0.085 in non-T lymphocytes (mean +/- SE).	Phospholipids	55-67	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
6594236-3	1984	The renal clearance (280.03 +/- 24.34 ml/min/1.73 m2) of imipenem was found to account for 69.2% of the corresponding plasma imipenem clearance (404.89 +/- 24.83 ml/min/1.73 m2).	Imipenem	57-65	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
6389166-6	1984	Experiments in monkeys with different anaesthetics resulted in flow values of 0.99 +/- 0.02, 1.47 +/- 0.09 and 0.99 +/- 0.04 microliter min-1 for pentobarbital, urethane and ketamine anaesthesia, respectively.	Pentobarbital	146-159	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
6094404-3	1984	Values of angiotensin-converting enzyme for benzoyl-Phe-Ala-Pro (Km = 10-11 microM; Amax = 12-13 mumol X min-1) were somewhat higher than published estimates in vitro and changed predictably in response to the known enzyme inhibitor captopril.	benzoylphenylalanyl-alanyl-proline	44-63	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
6487942-2	1984	The cyclist covered a distance of 694 km during the event at an average speed of 28.9 km.h-1 which corresponded to an equivalent oxygen cost of 38.5 ml.kg-1 min-1 and represented approximately 55% of his VO2 max.	Oxygen	129-135	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
6478739-5	1984	The phenylephrine dose required for an increase of 40 mm Hg in systolic blood pressure was 67 +/- 25 micrograms/min before cianopramine and 86 +/- 32 micrograms/min 2 hr after 2 mg cianopramine, which suggests weak alpha-receptor antagonism of cianopramine.	Phenylephrine	4-17	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
6547844-2	1984	Following an initial bolus dose of 0.6 mg kg-1, an infusion of atracurium was continued at an average rate of 0.0066 +/- 0.0003 mg kg-1 min-1 (0.4 mg kg-1 h-1) which was sufficient to maintain 90-95% block of the single twitch or train-of-four responses before bypass.	Atracurium	63-73	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
6467795-8	1984	min-1; 25% of metronidazole in the body at the beginning of hemodialysis was eliminated.	Metronidazole	14-27	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6488596-7	1984	During hypotonic saline diuresis GFR decreased further; a GFR of 19 ml/min/1.73 m2 was accompanied by a fractional distal sodium delivery of 96.5% and a fractional free water clearance of 73%.	Sodium Chloride	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
6499862-2	1984	Urapidil was given intravenously (0.5 mg kg-1 min-1 as a bolus) followed by infusion at a rate of 4 micrograms kg-1 min-1 for 120 min.	urapidil	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
6481335-7	1984	The average rate of NaCl entry under normal transporting conditions, estimated from Jv, assuming that the transported fluid is an isosmotic NaCl solution, was 22.5 nmol X cm-2 X min-1.	Sodium Chloride	20-24	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
6744790-3	1984	Serum prolactin decreased during infusion of dopamine at 0.01 micrograms min-1 kg-1 but a similar fall was found in the control group.	Dopamine	45-53	CD59 molecule (CD59 blood group)	Homo sapiens	73-83
6548391-1	1984	The effect of 0-1.0 M sucrose on the phase-transition properties of 1,2-dipalmitoyl-3-sn-phosphatidylcholine (1,2-DPPC) was examined by high-sensitivity differential scanning calorimetry at a scan rate of 0.1 K min-1.	colfosceril palmitate	68-108	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
6086640-10	1984	The rate of conversion of the reversible complex to the inactivated complex, at saturating ACVTP, was calculated to be 0.24 min-1.	acvtp	91-96	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
6430379-3	1984	Glucose at 5 mg kg-1 min-1 reduced urea excretion compared with glucose at 1 mg kg-1 min-1.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	21-26
6430379-3	1984	Glucose at 5 mg kg-1 min-1 reduced urea excretion compared with glucose at 1 mg kg-1 min-1.	Glucose	64-71	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
6744790-4	1984	When the rate of dopamine infusion was increased to 0.1 micrograms min-1 kg-1 a further substantial decrease in prolactin concentration occurred, whereas prolactin in the control group showed no change.	Dopamine	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	67-77
6744790-5	1984	At the end of the period of dopamine infusion at 0.1 micrograms min-1 kg-1 serum prolactin remained significantly (P less than 0.025) lower than in the control group (85 +/- 12 vs 180 +/- 21 m-units/1).	Dopamine	28-36	CD59 molecule (CD59 blood group)	Homo sapiens	64-74
6744790-7	1984	While dopamine infusion at 0.1 micrograms min-1 kg-1 caused significant inhibition of prolactin secretion in normal female subjects, other pituitary hormone secretion was not affected: it is suggested that under the conditions of this study dopamine in hypophysial portal blood is not of primary importance in the control of basal TSH, GH and LH release.	Dopamine	6-14	CD59 molecule (CD59 blood group)	Homo sapiens	42-52
6639824-8	1983	Mean halothane vapour uptake at a constant end-tidal concentration of 0.8% was 114 ml min-1 at 1 min, 36 ml min-1 at 5 min, 29 ml min-1 at 10 min and between 22 and 18 ml min-1 at 20-35 min.	Halothane	5-14	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
6479183-7	1984	(n = 10) or 100 mg oral dihydralazine (n = 8), cardiac output increased significantly from 4.0 to 6.7 l min-1 and from 4.7 to 7.7 l min-1 respectively (2P less than 0.001).	Dihydralazine	24-37	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
6479183-7	1984	(n = 10) or 100 mg oral dihydralazine (n = 8), cardiac output increased significantly from 4.0 to 6.7 l min-1 and from 4.7 to 7.7 l min-1 respectively (2P less than 0.001).	Dihydralazine	24-37	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
6431122-2	1984	Caloric intake was twice the predicted basal metabolic rate, with 5 mg kg-1 min-1 of glucose, 2.5 g kg-1 day-1 of amino acid and the remainder of calories supplied as a fat emulsion.	Glucose	85-92	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
6233979-3	1984	Rate-zonal centrifugation in a vertical rotor with a glycerol gradient results in a preparation of very high specific activity (6 mumoles min-1 mg protein-1 at 30 degrees C) and where over 70% of the protein corresponds to a polypeptide of about 100 kilodaltons previously identified as the ATPase.	Glycerol	53-61	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
6733113-3	1984	Iodoacetate and iodoacetamide inactivation followed pseudo-first-order kinetics with maximum inactivation rate constants of 1.56 min-1 and 0.87 min-1, respectively.	Iodoacetates	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
6733113-3	1984	Iodoacetate and iodoacetamide inactivation followed pseudo-first-order kinetics with maximum inactivation rate constants of 1.56 min-1 and 0.87 min-1, respectively.	Iodoacetates	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
6733113-3	1984	Iodoacetate and iodoacetamide inactivation followed pseudo-first-order kinetics with maximum inactivation rate constants of 1.56 min-1 and 0.87 min-1, respectively.	Iodoacetamide	16-29	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
6733113-3	1984	Iodoacetate and iodoacetamide inactivation followed pseudo-first-order kinetics with maximum inactivation rate constants of 1.56 min-1 and 0.87 min-1, respectively.	Iodoacetamide	16-29	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
6594113-6	1984	In one patient, naloxone in a dose of 400 micrograms reversed the decreased ventilatory responsiveness; the response to asphyxia was increased from 0.72 l min-1 % SaO-1 to 1.80 l min-1 % SaO2-1 (p less than 0.01) and the response to hypercapnia was increased from 0.90 l min-1 mmHg-1 to 4.80 l min-1 mmHg-1 (p less than 0.01).	Naloxone	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
6594113-6	1984	In one patient, naloxone in a dose of 400 micrograms reversed the decreased ventilatory responsiveness; the response to asphyxia was increased from 0.72 l min-1 % SaO-1 to 1.80 l min-1 % SaO2-1 (p less than 0.01) and the response to hypercapnia was increased from 0.90 l min-1 mmHg-1 to 4.80 l min-1 mmHg-1 (p less than 0.01).	Naloxone	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
6594113-6	1984	In one patient, naloxone in a dose of 400 micrograms reversed the decreased ventilatory responsiveness; the response to asphyxia was increased from 0.72 l min-1 % SaO-1 to 1.80 l min-1 % SaO2-1 (p less than 0.01) and the response to hypercapnia was increased from 0.90 l min-1 mmHg-1 to 4.80 l min-1 mmHg-1 (p less than 0.01).	Naloxone	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
6594113-6	1984	In one patient, naloxone in a dose of 400 micrograms reversed the decreased ventilatory responsiveness; the response to asphyxia was increased from 0.72 l min-1 % SaO-1 to 1.80 l min-1 % SaO2-1 (p less than 0.01) and the response to hypercapnia was increased from 0.90 l min-1 mmHg-1 to 4.80 l min-1 mmHg-1 (p less than 0.01).	Naloxone	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
6733699-1	1984	In regional hyperthermic perfusion with melphalan for patients with malignant melanoma of the leg, plasma leakage between the perfusion circuit and the systemic circulation was 4-7 ml X min-1.	Melphalan	40-49	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
6733835-4	1984	Maximal oxygen uptake average 5.09 l X min-1, or 76.0 ml X kg-1 X min-1, for the males, and 3.59 l X min-1, or 68.0 ml X kg-1 X min-1, for the females.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
6733835-4	1984	Maximal oxygen uptake average 5.09 l X min-1, or 76.0 ml X kg-1 X min-1, for the males, and 3.59 l X min-1, or 68.0 ml X kg-1 X min-1, for the females.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
6733835-4	1984	Maximal oxygen uptake average 5.09 l X min-1, or 76.0 ml X kg-1 X min-1, for the males, and 3.59 l X min-1, or 68.0 ml X kg-1 X min-1, for the females.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
6733835-4	1984	Maximal oxygen uptake average 5.09 l X min-1, or 76.0 ml X kg-1 X min-1, for the males, and 3.59 l X min-1, or 68.0 ml X kg-1 X min-1, for the females.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
6536512-3	1984	The systemic clearances of alphaxalone and alphadolone were 1.52 l min-1 and 1.09 l min-1 respectively (p less than 0.01).	alphaxalone	27-38	CD59 molecule (CD59 blood group)	Homo sapiens	67-81
6536512-3	1984	The systemic clearances of alphaxalone and alphadolone were 1.52 l min-1 and 1.09 l min-1 respectively (p less than 0.01).	alphaxalone	27-38	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
6536512-3	1984	The systemic clearances of alphaxalone and alphadolone were 1.52 l min-1 and 1.09 l min-1 respectively (p less than 0.01).	alphadolone	43-54	CD59 molecule (CD59 blood group)	Homo sapiens	67-81
6536512-3	1984	The systemic clearances of alphaxalone and alphadolone were 1.52 l min-1 and 1.09 l min-1 respectively (p less than 0.01).	alphadolone	43-54	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
6715370-7	1984	The Vmax values for thio-PC and thio-PE were 440 and 89 mumol min-1 mg-1, respectively.	Thio PC	20-27	CD59 molecule (CD59 blood group)	Homo sapiens	62-72
6715370-7	1984	The Vmax values for thio-PC and thio-PE were 440 and 89 mumol min-1 mg-1, respectively.	1,2-bis(decanoylthio)-1,2-dideoxyglycerol-3-phosphorylethanolamine	32-39	CD59 molecule (CD59 blood group)	Homo sapiens	62-72
6476347-4	1984	A loading infusion of 5 ml X min-1 of the chlormethiazole solution was followed by a variable rate of infusion in order to maintain a predetermined state of sedation--i.e. where the patient lapsed into sleep but was easily awakened to obey commands.	Chlormethiazole	42-57	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
6547048-1	1984	A continuous infusion of atracurium , at an average rate of 0.0061 +/- 0.0003 mg kg-1 min-1 for 128-233 min, to 12 anaesthetized patients undergoing prolonged surgical procedures, provided readily controllable neuromuscular blockade, and good operating conditions.	Atracurium	25-35	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
6378284-4	1984	The clearance of Tc-DTPA was higher in group PI (3.64 +/- 4.05% X min-1) than in group C2 (1.18 +/- 0.31% X min-1; p less than 0.01).	tc-dtpa	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
6378284-4	1984	The clearance of Tc-DTPA was higher in group PI (3.64 +/- 4.05% X min-1) than in group C2 (1.18 +/- 0.31% X min-1; p less than 0.01).	tc-dtpa	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
6562904-7	1984	The inactivation of chymotrypsin by 2-methyl-4H-3,1- benzoxazin -4-one (1b) is an equilibrium process (kinact = 1 X 10(4) M-1 min-1 and Keq = 2 X 10(6) M-1).	2-methyl-4h-3,1- benzoxazin -4-one	36-70	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
6712241-2	1984	The second-order rate constants for inactivation at pH 8.0 and 25 degrees C were 2.14 and 2.74 M-1 min-1 in the absence and presence of 50 mM borate, respectively.	Borates	142-148	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
6428907-3	1984	Long-term starvation enhanced ketone body turn-over almost 10-fold, whereas the disappearance rate for ketone bodies decreased from 0.035 to 0.015 min-1.	Ketones	103-109	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
6428907-4	1984	Under the same circumstances the turnover of acetate was about 1 mumol g-1 min-1 accounting for about 5% of FFA turnover.	Acetates	45-52	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
6725073-6	1984	These results suggest that the observed differences between men and women for peak VO2 elicited during arm cranking when expressed in traditional terms (1 X min-1 and ml X kg-1 X min-1) are a function of the size of the contracting muscle mass and are not due to sex-related differences in either O2 delivery or the O2 utilization capacity of the muscle itself.	Oxygen	84-86	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
6708050-4	1984	The reaction is catalyzed by hydroxide ion, Tris free base, and HPO4 2-, with catalytic constants of 0.032 min-1 (pH 8.0), 0.052, and 0.115 M-1 min-1, respectively.	hydroxide ion	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
6708050-4	1984	The reaction is catalyzed by hydroxide ion, Tris free base, and HPO4 2-, with catalytic constants of 0.032 min-1 (pH 8.0), 0.052, and 0.115 M-1 min-1, respectively.	hydroxide ion	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
6708050-4	1984	The reaction is catalyzed by hydroxide ion, Tris free base, and HPO4 2-, with catalytic constants of 0.032 min-1 (pH 8.0), 0.052, and 0.115 M-1 min-1, respectively.	Tromethamine	44-48	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
6708050-4	1984	The reaction is catalyzed by hydroxide ion, Tris free base, and HPO4 2-, with catalytic constants of 0.032 min-1 (pH 8.0), 0.052, and 0.115 M-1 min-1, respectively.	Tromethamine	44-48	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
6708050-4	1984	The reaction is catalyzed by hydroxide ion, Tris free base, and HPO4 2-, with catalytic constants of 0.032 min-1 (pH 8.0), 0.052, and 0.115 M-1 min-1, respectively.	hpo4	64-68	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
6708050-4	1984	The reaction is catalyzed by hydroxide ion, Tris free base, and HPO4 2-, with catalytic constants of 0.032 min-1 (pH 8.0), 0.052, and 0.115 M-1 min-1, respectively.	hpo4	64-68	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
6704271-4	1984	Nitrogen excretion did not exceed 100 ml min-1 and was measurable (8 ml min-1) at 100 min.	Nitrogen	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
6704785-5	1984	Phentolamine, a short-acting alpha-blocking agent, was administered as a continuous infusion of a 0.01 per cent solution, at a rate of 1 to 4 microgram X kg-1 X min-1 titrated according to the arterial blood pressure (BP), central venous pressure and urinary output.	Phentolamine	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
6362960-5	1984	ANG II (3 pmol kg-1 min-1) also produced a significantly (P less than 0.03) greater reduction in PAH clearance after (-194 +/- 40 ml/min) compared with before (-104 +/- 15 ml/min) captopril.	p-Aminohippuric Acid	97-100	CD59 molecule (CD59 blood group)	Homo sapiens	20-25
6362960-5	1984	ANG II (3 pmol kg-1 min-1) also produced a significantly (P less than 0.03) greater reduction in PAH clearance after (-194 +/- 40 ml/min) compared with before (-104 +/- 15 ml/min) captopril.	Captopril	180-189	CD59 molecule (CD59 blood group)	Homo sapiens	20-25
6373331-6	1984	Aqueous humor flow was 21% lower in clonidine-treated eyes as compared to fellow placebo-treated eyes, 1.9 microliter min-1 as compared to 2.4 microliters min-1.	Clonidine	36-45	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
6373331-6	1984	Aqueous humor flow was 21% lower in clonidine-treated eyes as compared to fellow placebo-treated eyes, 1.9 microliter min-1 as compared to 2.4 microliters min-1.	Clonidine	36-45	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
6723692-4	1984	After dosages up to 40 mg alinidine, heart rate decreased by 14 +/- 7 bpm, mean arterial pressure was reduced by 3 +/- 6 mmHg, stroke volume remained unchanged while cardiac output decreased 0.5 +/- 0.61 min-1 and systemic vascular resistance increased.	alinidine	26-35	CD59 molecule (CD59 blood group)	Homo sapiens	204-209
6711262-1	1984	In 58 infants and children with body weights between 2.8 and 20.5 kg carbon dioxide production (VCO2 ml min-1) was measured during halothane anaesthesia for minor surgical procedures.	Carbon Dioxide	69-83	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
6711262-6	1984	A respiratory quotient (RQ) of 0.8 was used to calculate oxygen consumption (VO2 ml min-1).	Oxygen	57-63	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
6419641-6	1984	A dopamine infusion (3 micrograms X kg-1 X min-1), which depressed hypoxic drive before the administration of droperidol, did not depress the hypoxic drive after droperidol.	Dopamine	2-10	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
6704158-7	1984	True AChE activity (measured in the presence of a maximally effective concentration of tetraisopropylpyrophosphoramide) had a Vmax of 13.4 +/- 0.17 nmoles X min-1 X mg protein)-1 and an apparent Km value of 1 X 10(-4)M acetylthiocholine.	Tetraisopropylpyrophosphamide	87-118	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
6704158-7	1984	True AChE activity (measured in the presence of a maximally effective concentration of tetraisopropylpyrophosphoramide) had a Vmax of 13.4 +/- 0.17 nmoles X min-1 X mg protein)-1 and an apparent Km value of 1 X 10(-4)M acetylthiocholine.	Acetylthiocholine	219-236	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
6230241-3	1984	Before and during phenytoin dosage in ten volunteers, the mean (+/-SD) total body clearance (ml min-1 kg-1) of both total and unbound prednisolone increased from 2.74 +/- 0.47 to 3.94 +/- 0.66 (P less than 0.001) and from 10.76 +/- 2.68 to 16.00 +/- 3.17 (P less than 0.001), respectively.	Phenytoin	18-27	CD59 molecule (CD59 blood group)	Homo sapiens	96-106
6230241-3	1984	Before and during phenytoin dosage in ten volunteers, the mean (+/-SD) total body clearance (ml min-1 kg-1) of both total and unbound prednisolone increased from 2.74 +/- 0.47 to 3.94 +/- 0.66 (P less than 0.001) and from 10.76 +/- 2.68 to 16.00 +/- 3.17 (P less than 0.001), respectively.	Prednisolone	134-146	CD59 molecule (CD59 blood group)	Homo sapiens	96-106
6197879-4	1984	After pentagastrin infusion there was an immediate increase in gastric histamine to a peak (median 1.62 nmol 10 min-1 p less than 0.01) followed by a fall and then a second peak (median 3.18 p less than 0.002).	Pentagastrin	6-18	CD59 molecule (CD59 blood group)	Homo sapiens	112-119
6197879-4	1984	After pentagastrin infusion there was an immediate increase in gastric histamine to a peak (median 1.62 nmol 10 min-1 p less than 0.01) followed by a fall and then a second peak (median 3.18 p less than 0.002).	Histamine	71-80	CD59 molecule (CD59 blood group)	Homo sapiens	112-119
6509730-9	1984	Administration of ephedrine and atropine increased HR temporarily from 56 to 90 and from 36 to 110 beats X min-1, respectively.	Ephedrine	18-27	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
6509730-9	1984	Administration of ephedrine and atropine increased HR temporarily from 56 to 90 and from 36 to 110 beats X min-1, respectively.	Atropine	32-40	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
6705283-3	1984	Each patient underwent a continuous infusion of dobutamine from 2.5 to 10 micrograms/kg min-1 with dosage increments of 2.5 micrograms/kg at 15-minute intervals.	Dobutamine	48-58	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
6705283-8	1984	However, 5 patients showed a decreased myocardial lactate extraction after 10 micrograms/kg min-1 of intravenous dobutamine, 3 from group I and 2 from group II.	Lactic Acid	50-57	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
6705283-8	1984	However, 5 patients showed a decreased myocardial lactate extraction after 10 micrograms/kg min-1 of intravenous dobutamine, 3 from group I and 2 from group II.	Dobutamine	113-123	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
6690194-2	1984	During a second study, adrenaline was infused intravenously in six resting subjects at a rate of 0.025 micrograms min-1 kg-1.	Epinephrine	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	114-124
6698715-5	1984	Remarkably, 1 retained its ability to acylate amines even in acid solution; the rate of acylation of L-Phe at pH 6.5 (15 M-1 X min-1) was about 20% of the rate at pH 10 (72 M-1 X min-1).	Phenylalanine	101-106	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
6698715-5	1984	Remarkably, 1 retained its ability to acylate amines even in acid solution; the rate of acylation of L-Phe at pH 6.5 (15 M-1 X min-1) was about 20% of the rate at pH 10 (72 M-1 X min-1).	Phenylalanine	101-106	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
6228661-5	1984	A complex is formed between [6-3H]3"-FFdUMP and dTMP synthetase, which is isolable on nitrocellulose filters, and has a dissociation rate (koffobsd = 1.4 X 10(-2) min-1) similar to that of the potent inhibitor 5-fluoro-2"-deoxyuridylate (koffobsd = 1.3 X 10(-2) min-1) from its ternary complex with dTMP synthetase.	[6-3h	28-33	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
6228661-5	1984	A complex is formed between [6-3H]3"-FFdUMP and dTMP synthetase, which is isolable on nitrocellulose filters, and has a dissociation rate (koffobsd = 1.4 X 10(-2) min-1) similar to that of the potent inhibitor 5-fluoro-2"-deoxyuridylate (koffobsd = 1.3 X 10(-2) min-1) from its ternary complex with dTMP synthetase.	[6-3h	28-33	CD59 molecule (CD59 blood group)	Homo sapiens	262-267
6228661-5	1984	A complex is formed between [6-3H]3"-FFdUMP and dTMP synthetase, which is isolable on nitrocellulose filters, and has a dissociation rate (koffobsd = 1.4 X 10(-2) min-1) similar to that of the potent inhibitor 5-fluoro-2"-deoxyuridylate (koffobsd = 1.3 X 10(-2) min-1) from its ternary complex with dTMP synthetase.	5-fluoro-2"-deoxyuridylate	210-236	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
6228661-5	1984	A complex is formed between [6-3H]3"-FFdUMP and dTMP synthetase, which is isolable on nitrocellulose filters, and has a dissociation rate (koffobsd = 1.4 X 10(-2) min-1) similar to that of the potent inhibitor 5-fluoro-2"-deoxyuridylate (koffobsd = 1.3 X 10(-2) min-1) from its ternary complex with dTMP synthetase.	5-fluoro-2"-deoxyuridylate	210-236	CD59 molecule (CD59 blood group)	Homo sapiens	262-267
6482327-3	1984	Nicotine was applied as salicylate via subcutaneously implanted osmotic minipumps at a dosage of 1 microgram/kg/min = 1.44 mg/kg/day, corresponding to heavy smoking in humans.	Nicotine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	112-119
6643476-9	1983	The internalization rate constant for 125I-Man43-AI-BSA, 1.23 (+/- 0.20) min-1, was similar to that constant obtained for 125I-Man13-AI-BSA, 1.80 (+/- 0.67) min-1.	Iodine-125	38-43	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
6666523-9	1983	A concomitant increase in oxygen uptake in preportal tissues occurred (19.9 ml min-1 vs 24.5 ml X min-1).	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
6666523-9	1983	A concomitant increase in oxygen uptake in preportal tissues occurred (19.9 ml min-1 vs 24.5 ml X min-1).	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
6689270-1	1983	Diethyl pyrocarbonate inhibited diaphorase activity of ferredoxin-NADP+ oxidoreductase with a second-order rate constant of 2 mM-1 X min-1 at pH 7.0 and 20 degrees C, showing a concomitant increase in absorbance at 242 nm due to formation of carbethoxyhistidyl derivatives.	Diethyl Pyrocarbonate	0-21	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
6689270-1	1983	Diethyl pyrocarbonate inhibited diaphorase activity of ferredoxin-NADP+ oxidoreductase with a second-order rate constant of 2 mM-1 X min-1 at pH 7.0 and 20 degrees C, showing a concomitant increase in absorbance at 242 nm due to formation of carbethoxyhistidyl derivatives.	carbethoxyhistidyl	242-260	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
6689270-8	1983	Modification of the flavoprotein in the presence of NADP+, i.e., with full preservation of diaphorase activity, resulted in a significant impairment of cytochrome c reductase activity, with a second-order rate constant for inactivation of about 0.5 mM-1 X min-1.	NADP	52-57	CD59 molecule (CD59 blood group)	Homo sapiens	256-261
6422790-13	1983	The inadequate analgetic effect of pentazocine manifests itself in an only slight initial reduction of the respiratory rate (19.5 leads to 17.5 min-1), which, on the other hand, decreases significantly and continuously under buprenorphine (20.8 leads to 13.5 min-1).	Pentazocine	35-46	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
6422790-13	1983	The inadequate analgetic effect of pentazocine manifests itself in an only slight initial reduction of the respiratory rate (19.5 leads to 17.5 min-1), which, on the other hand, decreases significantly and continuously under buprenorphine (20.8 leads to 13.5 min-1).	Pentazocine	35-46	CD59 molecule (CD59 blood group)	Homo sapiens	259-264
6546186-9	1983	Groups V and VIII received 3-hour intra-arterial infusions of PGE1 (10(-1) micrograms/kg-1 min-1).	Alprostadil	62-66	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
6362696-1	1983	Epoprostenol (prostacyclin, PGI2) was given intravenously to seven healthy volunteers in a dose of 4 ng kg-1 min-1 over a 30 min period.	Epoprostenol	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
6426452-4	1983	Although prochlorperazine increased waking ventilatory responsiveness to asphyxia in five of six patients with OSA (2.26 +/- 0.44 l min-1.% SaO2 vs. 4.77 +/- 1.39 l min-1.% SaO2; mean +/- SEM; p less than 0.01), the drug had no clinically significant effect on upper airway obstruction during sleep; in three patients, apnea frequency was slightly reduced but in four of six patients severity of hypoxemia during apnea was increased with drug administration.	Prochlorperazine	9-25	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
6426452-4	1983	Although prochlorperazine increased waking ventilatory responsiveness to asphyxia in five of six patients with OSA (2.26 +/- 0.44 l min-1.% SaO2 vs. 4.77 +/- 1.39 l min-1.% SaO2; mean +/- SEM; p less than 0.01), the drug had no clinically significant effect on upper airway obstruction during sleep; in three patients, apnea frequency was slightly reduced but in four of six patients severity of hypoxemia during apnea was increased with drug administration.	Prochlorperazine	9-25	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
6662115-5	1983	When the two hypertensive groups were compared with each other the HP group showed a shortened LVET and a prolonged PEP (P less than 0.01), and also a slower heart rate (HP 74 +/- 3 b min-1.	histidylproline	67-69	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
6420545-5	1983	The observed glycogenolytic rate increased during occlusion up to 0.8 mmol glycosyl units kg-1 dry muscle min-1.	glycosyl	75-83	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
6197766-2	1983	20 patients received a constant dose of 8 ng kg-1 min-1 of prostacyclin (PGI2), beginning two minutes before extracorporeal circulation (ECC) and ending together with ECC.	Epoprostenol	59-71	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
6417077-10	1983	The dopamine infusion caused the fast loop gain to be significantly (P less than 0.05) reduced from 0.64 to 0.19 l X min-1 X Torr-1, while the slow loop gain was unchanged.	Dopamine	4-12	CD59 molecule (CD59 blood group)	Homo sapiens	117-131
6639842-5	1983	Rifampicin (600 mg/day) caused a large increase in propranolol"s oral clearance (35.7 +/- 16.3 vs 96.1 +/- 26.9 ml min-1 kg-1, mean +/- s.d.	Rifampin	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	115-125
6355421-12	1983	The clearance of captopril from patients with kidney failure ranged from 14.1 to 18.8 ml/min/kg in five subjects with creatine clearance between 10 and 21 ml/min/1.73 m2.	Captopril	17-26	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
6317014-5	1983	The rate constant for the water reaction was found to be very small, approximately equal to 2.5 X 10(-6) min-1.	Water	26-31	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
6584678-2	1983	Severe renal failure (CCr less than 15 ml/min/1.73 m2) was associated with a reduction in 1,25(OH)2D to 25% of mean normal levels, a very high PTH/1,25(OH)2D ratio of 75 (normal = 0.74), and a 60% reduction of serum 24,25(OH)2D.	,25(oh)2d	91-100	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
6639987-5	1983	Thiophosphonate--C8H17O(CH3)P(O)-SCH2SCH2COOCH3 was found to be a highly efficient selective inhibitor of aphis carboxylesterase, i. e. the kII values for carboxylesterase and cholinesterase were equal to 10(8) and 10(5) M-1 min-1, respectively.	thiophosphonate--c8h17o(ch3)p	0-29	CD59 molecule (CD59 blood group)	Homo sapiens	225-230
6639987-5	1983	Thiophosphonate--C8H17O(CH3)P(O)-SCH2SCH2COOCH3 was found to be a highly efficient selective inhibitor of aphis carboxylesterase, i. e. the kII values for carboxylesterase and cholinesterase were equal to 10(8) and 10(5) M-1 min-1, respectively.	(o)-sch2sch2cooch3	29-47	CD59 molecule (CD59 blood group)	Homo sapiens	225-230
6885755-2	1983	Purified choline acetyltransferase had a specific activity of 142 mumol of acetylcholine produced min-1 mg-1 and consisted of two proteic forms with Mr = 72,000 and 76,000 on sodium dodecyl sulfate gel electrophoresis.	Acetylcholine	75-88	CD59 molecule (CD59 blood group)	Homo sapiens	98-108
6624925-6	1983	Cardiac output was directly proportional to the rate of O2 consumption (VO2, ml X min-1): Q = 17.5 VO2(1.04), with birds having a greater cardiac output for a given VO2 than mammals.	Oxygen	56-58	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
6626202-2	1983	The compounds evaluated and their respective oxidation rates at pH 7.4 are in uM X min-1: ascorbate, 0.70; 5 methyl 3,4 dihydroxytetrone, 0.65; D-iso ascorbate, 0.73; and ascorbyl palmitate, 0.64.	Ascorbic Acid	90-99	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
6626425-5	1983	Chlorthalidone induced significant reductions in calculated mean arterial pressure, which fell from 135 +/- 4 to 117 +/- 4 mm Hg, and the dilator response to verapamil at 5 micrograms/min, which was reduced from 2.4 +/- 0.2 to 1.5 +/- 0.2 ml min-1 100 ml-1 forearm; the response to sodium nitroprusside at 3.2 micrograms/min was not significantly changed.	Chlorthalidone	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	242-247
6626425-6	1983	Atenolol induced significant reductions in mean arterial pressure, which fell from 134 +/- 6 to 123 +/- 6 mm Hg, heart rate which fell from 72 +/- 3 to 55 +/- 2 beats/min, and response to verapamil at 5 micrograms/min which fell from 2.7 +/- 0.2 to 2.1 +/- 0.2 ml min-1 100 ml-1 forearm; the response to sodium nitroprusside was not significantly changed.	Atenolol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	264-269
6416659-3	1983	Propranolol caused a significant (p less than 0.05) reduction in peak oxygen uptake (VO2) during both the 30-s and 4-min tests (30-s ND, 3949 +/- 718 mL X min-1 (means +/- SD); 30-s P, 3408 +/- 778 mL X min-1; 4-min ND, 4058 +/- 409 mL X min-1; 4-min P, 3725 +/- 573 mL X min-1).	Propranolol	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
6416659-3	1983	Propranolol caused a significant (p less than 0.05) reduction in peak oxygen uptake (VO2) during both the 30-s and 4-min tests (30-s ND, 3949 +/- 718 mL X min-1 (means +/- SD); 30-s P, 3408 +/- 778 mL X min-1; 4-min ND, 4058 +/- 409 mL X min-1; 4-min P, 3725 +/- 573 mL X min-1).	Propranolol	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
6416659-3	1983	Propranolol caused a significant (p less than 0.05) reduction in peak oxygen uptake (VO2) during both the 30-s and 4-min tests (30-s ND, 3949 +/- 718 mL X min-1 (means +/- SD); 30-s P, 3408 +/- 778 mL X min-1; 4-min ND, 4058 +/- 409 mL X min-1; 4-min P, 3725 +/- 573 mL X min-1).	Propranolol	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
6416659-3	1983	Propranolol caused a significant (p less than 0.05) reduction in peak oxygen uptake (VO2) during both the 30-s and 4-min tests (30-s ND, 3949 +/- 718 mL X min-1 (means +/- SD); 30-s P, 3408 +/- 778 mL X min-1; 4-min ND, 4058 +/- 409 mL X min-1; 4-min P, 3725 +/- 573 mL X min-1).	Propranolol	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
6887834-15	1983	min-1 during adenosine infusion resulted in a decrease in mean aortic pressure (63% of control value) and a marked further reduction in blood flow to the LV papillary muscles as well as the LV subendocardium, while MBF increased dramatically in the LV subepicardium compared to values observed during ventricular pacing at 250 beats .	Adenosine	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6311199-3	1983	With histone H1 as substrate, the Km"s obtained with Ca2+ and Ni2+ were 2.2 and 4.2 microM, and the kcat"s were 0.5 and 24.3 min-1, respectively.	Nickel(2+)	62-66	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
6687888-5	1983	The second order rate constant for the thrombin-HCII reaction reached a maximum value of 6.4 X 10(8) M-1 min-1 in the presence of 250-500 micrograms/ml of dermatan sulfate compared to 3.8 X 10(8) M-1 min-1 in the presence of 40-80 micrograms/ml of heparin.	Dermatan Sulfate	155-171	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
6626702-5	1983	The renal clearance of sulphamerazine (20 ml min-1) and N4-acetylsulphamerazine (300-500) ml min-1) is independent of the acetylator type and the origin of the compound.	Sulfamerazine	23-37	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
6626702-5	1983	The renal clearance of sulphamerazine (20 ml min-1) and N4-acetylsulphamerazine (300-500) ml min-1) is independent of the acetylator type and the origin of the compound.	n4-acetylsulphamerazine	56-79	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
6687888-5	1983	The second order rate constant for the thrombin-HCII reaction reached a maximum value of 6.4 X 10(8) M-1 min-1 in the presence of 250-500 micrograms/ml of dermatan sulfate compared to 3.8 X 10(8) M-1 min-1 in the presence of 40-80 micrograms/ml of heparin.	Dermatan Sulfate	155-171	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
6687888-5	1983	The second order rate constant for the thrombin-HCII reaction reached a maximum value of 6.4 X 10(8) M-1 min-1 in the presence of 250-500 micrograms/ml of dermatan sulfate compared to 3.8 X 10(8) M-1 min-1 in the presence of 40-80 micrograms/ml of heparin.	Heparin	248-255	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
6859187-5	1983	The calculated coefficient of exchange of fluorescein across the blood-aqueous barrier was 30.7 X 10(-4) min-1 in the affected eyes and 5.7 X 10(-4) min-1 in the unaffected eyes.	Fluorescein	42-53	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
6344653-5	1983	min-1 for plasma glucose concentrations of 60, 95, and 160 mg/dl, respectively) produced a linear Eadie-Hofstee plot, suggesting that insulin-independent glucose uptake followed Michaelis-Menten kinetics.	Glucose	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6344653-5	1983	min-1 for plasma glucose concentrations of 60, 95, and 160 mg/dl, respectively) produced a linear Eadie-Hofstee plot, suggesting that insulin-independent glucose uptake followed Michaelis-Menten kinetics.	Glucose	154-161	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6883619-5	1983	Total body maximal oxygen uptake averaged (+/- SD) 5.36 +/- 0.25 l X min-1.	Oxygen	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
6134537-5	1983	In patients in sinus rhythm, fazadinium produced a decrease in total peripheral resistance, which was maximum at the 1st min (delta TPRI -738 +/- 88 dyn s cm-5 m2) and accompanied by a moderate decrease in arterial pressure (MAP -27 +/- 2.4 mm Hg) and cardiac index (delta CI -0.23 +/- 0.17 litre min-1 m-2) and a moderate increase in heart rate (delta HR +16 +/- 5.7 beat min-1).	fazadinium	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	297-302
6134537-5	1983	In patients in sinus rhythm, fazadinium produced a decrease in total peripheral resistance, which was maximum at the 1st min (delta TPRI -738 +/- 88 dyn s cm-5 m2) and accompanied by a moderate decrease in arterial pressure (MAP -27 +/- 2.4 mm Hg) and cardiac index (delta CI -0.23 +/- 0.17 litre min-1 m-2) and a moderate increase in heart rate (delta HR +16 +/- 5.7 beat min-1).	fazadinium	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	373-378
6618768-3	1983	The patient"s creatinine clearance decreased from 25 ml/min/1.73 m2 to 10-13 ml/min/1.73 m2 following the acute nephritic episode and chronic dialysis therapy was required thereafter.	Creatinine	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
6618768-3	1983	The patient"s creatinine clearance decreased from 25 ml/min/1.73 m2 to 10-13 ml/min/1.73 m2 following the acute nephritic episode and chronic dialysis therapy was required thereafter.	Creatinine	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
6133986-3	1983	During the 39 month (range 28-48) period of antihypertensive treatment with metoprolol, hydralazine, and frusemide (furosemide) or thiazide, arterial blood pressure fell from 144/97 mm Hg (mean of all pretreatment values) to 128/84 mm Hg (mean of all post-treatment values), urinary albumin excretion from 977 micrograms/min to 433 micrograms/min, and GFR from 80 to 62 ml/min/1 .	Metoprolol	76-86	CD59 molecule (CD59 blood group)	Homo sapiens	373-378
6133986-3	1983	During the 39 month (range 28-48) period of antihypertensive treatment with metoprolol, hydralazine, and frusemide (furosemide) or thiazide, arterial blood pressure fell from 144/97 mm Hg (mean of all pretreatment values) to 128/84 mm Hg (mean of all post-treatment values), urinary albumin excretion from 977 micrograms/min to 433 micrograms/min, and GFR from 80 to 62 ml/min/1 .	Furosemide	105-114	CD59 molecule (CD59 blood group)	Homo sapiens	373-378
6133986-3	1983	During the 39 month (range 28-48) period of antihypertensive treatment with metoprolol, hydralazine, and frusemide (furosemide) or thiazide, arterial blood pressure fell from 144/97 mm Hg (mean of all pretreatment values) to 128/84 mm Hg (mean of all post-treatment values), urinary albumin excretion from 977 micrograms/min to 433 micrograms/min, and GFR from 80 to 62 ml/min/1 .	Furosemide	116-126	CD59 molecule (CD59 blood group)	Homo sapiens	373-378
6131688-7	1983	The data exclude (95% confidence limit) the possibility that occupational exposure to styrene at concentrations about 50 ppm stimulates the microsomal enzyme function of the liver to a degree compatible with an increase in antipyrine clearance of more than 2 ml x min-1 (3%).	Styrene	86-93	CD59 molecule (CD59 blood group)	Homo sapiens	264-269
6831836-5	1983	On a separate occasion, two doses of L-adrenaline (0.025 micrograms min-1 kg-1 and 0.05 micrograms min-1 kg-1) were infused in the same subjects at rest to produce two mean plasma levels similar to those found on exercise.	Epinephrine	37-49	CD59 molecule (CD59 blood group)	Homo sapiens	68-84
6337767-6	1983	Hyperinsulinaemia increased (P less than 0.05) the secretion of aldosterone during the largest dose of angiotensin II (20 ng min-1 kg-1), but had no effect on the rise in blood pressure after angiotensin II.	Aldosterone	64-75	CD59 molecule (CD59 blood group)	Homo sapiens	125-135
6682738-5	1983	If this difference, partly or fully, is due to extrahepatic extrarenal elimination, the clinical test for galactose elimination needs a correction (of the order of magnitude of 0.7 mmol min-1) to serve as an absolute measure of the hepatic functional capacity, but since the hepatic uptake rate may be underestimated following a single injection, the correction may be smaller.	Galactose	106-115	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
6553015-10	1983	The bimolecular velocity constant for the inhibition by diisopropyl fluoro phosphate was determined as 10.5 l x mol-1 x min-1.	Isoflurophate	56-84	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
6831830-7	1983	The (mean +/- SD) rate constant for equilibration of alcuronium concentration and effect was found to be 0.24 +/- 0.11 min-1, whereas the steady-state concentration required to induce 95% paralysis was 0.91 +/- 0.35 micrograms/ml (mean +/- SD).	Alcuronium	53-63	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
6553016-7	1983	The bimolecular velocity constant for the inhibition by diisopropyl fluorophosphate was determined as 8 l x mol-1 x min-1.	Isoflurophate	56-83	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
6602342-3	1983	The kinetics of the washout curve of 3H ouabain (added together with unlabelled drug, shows, in addition to the slow exponential component of about the same time constant (0.2 min-1) previously seen, another component with a 10 times longer time constant, related to ineffective drug concentrations and corresponding to a washout from aspecific sites.	3h ouabain	37-47	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
6338763-2	1983	Nitroprusside was infused intravenously for one hour at rates adjusted to achieve a 20% decrease in mean blood pressure (dose range: 14-50 mg, or about 5.8-18.5 micrograms X kg-1 X min-1).	Nitroprusside	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
6673053-4	1983	Mean oxygen consumption in the prehepatic splanchnic area was 0.27 +/- 0.04 ml X min-1 X kg-1.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
6409409-3	1983	Noradrenaline (0.5 micrograms X kg-1 X min-1) caused a fall in ventricular fibrillation threshold from 30 to 20 mA (P less than 0.001).	Norepinephrine	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
6847640-7	1983	Unstimulated platelets were found to consume about 3.5 and 0.5 mumol of ATP equivalents x min-1 x (10(11) cells)-1 at 37 degrees C and 15 degrees C, respectively; the thrombin-treated platelets consumed respectively 16 and 2 mumol of ATP equivalents x min-1 x (10(11) cells)-1 at these temperatures.	Adenosine Triphosphate	72-75	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
27463166-2	1983	Before the program they had 12.2% body fat and maximal oxygen consumption of 64.7 ml  kg(-1)  min(-1) during bicycle ergometry.	Oxygen	55-61	CD59 molecule (CD59 blood group)	Homo sapiens	94-100
6419648-10	1983	In this series, the association of optimal volume loading with a peroperative perfusion of 0.2 micrograms X kg-1 X min-1 NTG gave a good haemodynamic stability.	Nitroglycerin	121-124	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
6625245-6	1983	min-1 sodium nitroprusside was given at the start of surgery, and immediately afterwards.	Nitroprusside	6-26	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6625257-3	1983	min-1 with a correlation coefficient of 0.999 between measured and independently verified rates and amounts of water evaporation.	Water	111-116	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6821619-6	1983	Total body clearance of pyridostigmine was 8.7 +/- 1.5 ml min-1 kg-1, and the total apparent volume of distribution was 536 +/- 80 ml kg-1.	Pyridostigmine Bromide	24-38	CD59 molecule (CD59 blood group)	Homo sapiens	58-68
6685029-4	1983	Maximal oxygen uptake VO2max) in the fast group (X +/- SD; 45.3 +/- 5.5 ml x kg-1 x min-1) was significantly greater (p less than 0.05) than the slow group (39.8 +/- 5.9 ml x kg-1 x min-1).	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
6840170-4	1983	By contrast, the area under the plasma concentration versus time curve was much smaller during (mean 262 nmol/1 X h) than after (mean 1298 nmol/1 X h) pregnancy, resulting in an average apparent oral clearance (Clo) of metoprolol that was 4.4 times higher during (362 ml X kg-1 body-weight X min-1) than after pregnancy.	Metoprolol	219-229	CD59 molecule (CD59 blood group)	Homo sapiens	292-297
6833995-4	1983	It decreased hyperbolically with increasing Clo to 14-16 mmol (kg cell solids)-1 min-1.	clo	44-47	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
6833995-6	1983	In the presence of the anion exchange inhibitor DNDS, net efflux was reduced to 5 mmol (kg cell solids)-1 min-1, independent of Clo.	4,4'-dinitro-2,2'-stilbenedisulfonic acid	48-52	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
6853962-7	1983	The second order (reaction) rate constant for base hydrolysis of aldicarb sulfone is 40.3 (+/- 0.5) liter mole-1min-1; for acid catalyzed hydrolysis it is 7.33 (+/- 0.06) X 10(-4) liter mole-1min-1.	aldicarb sulfone	65-81	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
6361440-6	1983	As a result of the GP feedings the rate of carbohydrate utilization during the GP trial was 0.53 g X min-1 greater than during the C trial.	Carbohydrates	43-55	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
6878259-4	1983	CAPD treatment was terminated as renal function improved and a creatinine clearance of 20 ml/min/1.73m2 was achieved.	Creatinine	63-73	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
7150961-3	1982	The mean glutathione peroxidase activity in the CSF was 6.2 nmol NADPH oxidized min-1 .	NADP	65-70	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
6816098-10	1982	min-1 (n = 10) of etomidate in air-oxygen mixture.	Etomidate	18-27	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6816098-10	1982	min-1 (n = 10) of etomidate in air-oxygen mixture.	Oxygen	35-41	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6819169-1	1982	This study was designed to evaluate the influence of intravenous infusion (72 mg min-1) of lysine acetylsalicylate (LAS), an inhibitor of endogenous prostaglandin synthesis, on glucose homeostasis in normal man.	acetylsalicylic acid lysinate	91-114	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
6819169-1	1982	This study was designed to evaluate the influence of intravenous infusion (72 mg min-1) of lysine acetylsalicylate (LAS), an inhibitor of endogenous prostaglandin synthesis, on glucose homeostasis in normal man.	acetylsalicylic acid lysinate	116-119	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
6819169-1	1982	This study was designed to evaluate the influence of intravenous infusion (72 mg min-1) of lysine acetylsalicylate (LAS), an inhibitor of endogenous prostaglandin synthesis, on glucose homeostasis in normal man.	Glucose	177-184	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
6219103-2	1982	(1974) has been modified to yield a H+-ATPase with high levels of Pi-ATP exchange activity (400-600 nmol x min-1 x mg-1).	Adenosine Triphosphate	39-42	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
6219103-3	1982	This activity is further enhanced (1400-1600 nmol x min-1 x mg-1) following sucrose density gradient centrifugation in the presence of asolectin.	Sucrose	76-83	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
6128020-3	1982	3 Noradrenaline 5.0 micrograms min-1 and isoprenaline 1.0 microgram min-1 significantly increased ventilation and CO2 production and decreased alveolar PCO2.	Norepinephrine	2-15	CD59 molecule (CD59 blood group)	Homo sapiens	31-57
6128020-3	1982	3 Noradrenaline 5.0 micrograms min-1 and isoprenaline 1.0 microgram min-1 significantly increased ventilation and CO2 production and decreased alveolar PCO2.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	114-117	CD59 molecule (CD59 blood group)	Homo sapiens	31-57
7116784-8	1982	Glucose turnover, assessed by the use of [6,6-2H]glucose, was 11.4 (+/- 0.9) micromol min-1 kg-1 and 11.6 (+/- 0.5) micromol min-1 kg-1 with rate of glucose was 2.3 (+/- 0.3) ml min-1 kg-1 with both isotopically labelled tracers.	[6,6-2h]glucose	41-56	CD59 molecule (CD59 blood group)	Homo sapiens	86-105
7116784-8	1982	Glucose turnover, assessed by the use of [6,6-2H]glucose, was 11.4 (+/- 0.9) micromol min-1 kg-1 and 11.6 (+/- 0.5) micromol min-1 kg-1 with rate of glucose was 2.3 (+/- 0.3) ml min-1 kg-1 with both isotopically labelled tracers.	Glucose	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	86-105
7159691-2	1982	Following the rapid attainment of peak concentrations, plasma concentrations fell by approximately 50 per cent in 24 h. After the first dose of chlorbutol, the terminal elimination half-life was 10.3 +/-1.3 days (mean +/- S.E.M), the volume of distribution was 233 +/- 141 and the plasma clearance was 11.6 +/- 1.0 ml min-1.	Chlorobutanol	144-154	CD59 molecule (CD59 blood group)	Homo sapiens	318-323
7116756-4	1982	Intravenous pindolol resulted in decreased mean heart rate (74.3 to 67 bpm) and decreased mean inulin clearance (66 to 60.5 ml/min/1.73 m2.)	Pindolol	12-20	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
6223950-4	1982	The absorption rate from 0.1 M HgCl2 solution decreased from 9.3 micrograms cm-2 min-1 during a 5 min exposure to 2.5 micrograms cm-2 min-1 during a 1 h exposure.	Mercuric Chloride	31-36	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
6223950-4	1982	The absorption rate from 0.1 M HgCl2 solution decreased from 9.3 micrograms cm-2 min-1 during a 5 min exposure to 2.5 micrograms cm-2 min-1 during a 1 h exposure.	Mercuric Chloride	31-36	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
6223950-5	1982	A ten-fold decrease of HgCl2 concentration resulted in an approximately ten-fold decrease of the absorption rate, from 4.6 to 0.4 microgram cm-2 min-1 during a 30 min exposure.	Mercuric Chloride	23-28	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
6128027-3	1982	One of these, ATPase III, has been purified to apparent homogeneity as judged by polyacrylamide gel electrophoresis and has a specific activity of 12 mumol of ATP hydrolyzed min-1 (mg of protein)-1.	polyacrylamide gels	81-99	CD59 molecule (CD59 blood group)	Homo sapiens	174-197
6128027-3	1982	One of these, ATPase III, has been purified to apparent homogeneity as judged by polyacrylamide gel electrophoresis and has a specific activity of 12 mumol of ATP hydrolyzed min-1 (mg of protein)-1.	Adenosine Triphosphate	14-17	CD59 molecule (CD59 blood group)	Homo sapiens	174-197
7142347-4	1982	With a mobile phase of methanol-water (75:25, v/v) containing 2.5% (v/v) acetic acid and adjusted to pH 5.25 with 10 M sodium hydroxide, a mixture of fifteen bile acids could be resolved, and the ten major conjugated bile acids of human bile were well separated in under 20 min at a flow-rate of 2.0 ml min-1.	Bile Acids and Salts	158-168	CD59 molecule (CD59 blood group)	Homo sapiens	303-308
7126410-4	1982	4 The serum clearance of methaqualone on day 15 was higher (mean value 94.6 ml min-1 on day 1, 176.0 ml min-1 on day 15), serum half-life shorter (mean t1/2 beta 16.3 h on day 1, 11.6 h on day 15) and the AUC alpha smaller (mean value 44.0 micrograms ml-1 h on day 1, 24.4 micrograms ml-1 h on day 15) than on day 1.	Methaqualone	25-37	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
7126410-4	1982	4 The serum clearance of methaqualone on day 15 was higher (mean value 94.6 ml min-1 on day 1, 176.0 ml min-1 on day 15), serum half-life shorter (mean t1/2 beta 16.3 h on day 1, 11.6 h on day 15) and the AUC alpha smaller (mean value 44.0 micrograms ml-1 h on day 1, 24.4 micrograms ml-1 h on day 15) than on day 1.	Methaqualone	25-37	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
7105623-8	1982	Dialysis clearance of conjugated 10-hydroxynortriptyline was 58 +/- 8 (SD) ml min-1, but nortriptyline and unconjugated 10-hydroxynortriptyline were not appreciably removed by dialysis.	10-hydroxynortriptyline	33-56	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
7105623-8	1982	Dialysis clearance of conjugated 10-hydroxynortriptyline was 58 +/- 8 (SD) ml min-1, but nortriptyline and unconjugated 10-hydroxynortriptyline were not appreciably removed by dialysis.	Nortriptyline	43-56	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
6811529-6	1982	Ventilatory responses to rebreathing CO2 (6 subj) were 1.7 +/- 0.3 1 X min-1 X Torr-1 during W and 1.3 +/- 0.2 during SWS.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	37-40	CD59 molecule (CD59 blood group)	Homo sapiens	71-102
7153872-3	1982	Renal clearance (85 ml min-1) contributed 65% to the total elimination of bumetanide irrespective of whether a model-dependent or model-independent method was used.	Bumetanide	74-84	CD59 molecule (CD59 blood group)	Homo sapiens	23-28
7102704-5	1982	The overall mean acyclovir plasma half-life and total body clearance +/- SD were 2.1 +/- 0.5 hours and 297 +/- 53 ml/min/1.73 m2.	Acyclovir	17-26	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
7084110-4	1982	The rate of pregnenolone biosynthesis in the presence of cholesterol (50 microM) was 0.2 nmol min-1 mg-1 protein.	Pregnenolone	12-24	CD59 molecule (CD59 blood group)	Homo sapiens	94-104
7084110-4	1982	The rate of pregnenolone biosynthesis in the presence of cholesterol (50 microM) was 0.2 nmol min-1 mg-1 protein.	Cholesterol	57-68	CD59 molecule (CD59 blood group)	Homo sapiens	94-104
7082602-2	1982	In those who were not in labour dopamine infusion (2 micrograms min-1 kg-1 body weight) induced regular uterine contractions and with higher doses the response increased.	Dopamine	32-40	CD59 molecule (CD59 blood group)	Homo sapiens	64-74
7082602-3	1982	For women in spontaneous labour, dopamine at a dose of 4 micrograms min-1 kg-1 caused a significant increase in the frequency of contraction, but in women receiving an oxytocin infusion, no further stimulation was seen.	Dopamine	33-41	CD59 molecule (CD59 blood group)	Homo sapiens	68-78
7044465-4	1982	PGE1 0.1-0.2 ng kg-1 body weight min-1 was administered.	Alprostadil	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
6809473-2	1982	The serum clearance of furosemide (Cls) was between 140 and 201 ml min-1 and on the average the renal clearance was 60% of Cls.	Furosemide	23-33	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
6809473-2	1982	The serum clearance of furosemide (Cls) was between 140 and 201 ml min-1 and on the average the renal clearance was 60% of Cls.	calusterone	35-38	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
6809473-3	1982	During the initial 30 min period a maximum additional excretion rate of sodium of 3.3 mmol min-1 was reached at an excretion rate of 0.8 mg furosemide min-1.	Sodium	72-78	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
6809473-3	1982	During the initial 30 min period a maximum additional excretion rate of sodium of 3.3 mmol min-1 was reached at an excretion rate of 0.8 mg furosemide min-1.	Sodium	72-78	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
6809473-3	1982	During the initial 30 min period a maximum additional excretion rate of sodium of 3.3 mmol min-1 was reached at an excretion rate of 0.8 mg furosemide min-1.	Furosemide	140-150	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
6809473-3	1982	During the initial 30 min period a maximum additional excretion rate of sodium of 3.3 mmol min-1 was reached at an excretion rate of 0.8 mg furosemide min-1.	Furosemide	140-150	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
6809475-1	1982	The pressor response to both angiotensin II (5, 10 and 20 ng kg-1 min-1) and to noradrenaline (50, 100 and 200 ng kg-1 min-1) was reduced (P less than 0.05 to less than 0.005) in six healthy male subjects following the administration of the calcium-antagonist nifedipine (10 mg p.o.).	Norepinephrine	80-93	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
7048841-5	1982	Following atropine, heart rate increased by about 25 beats min-1, whereas only very slight increases were seen in the non-atropine groups.	Atropine	10-18	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
6297992-2	1983	Apparent initial rates of autophosphorylation in the absence of cyclic nucleotides and in the presence of cGMP and cAMP are 0.006, 0.04, 0.4 mol Pi incorp./min-1.	Cyclic GMP	106-110	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
6297992-2	1983	Apparent initial rates of autophosphorylation in the absence of cyclic nucleotides and in the presence of cGMP and cAMP are 0.006, 0.04, 0.4 mol Pi incorp./min-1.	Cyclic AMP	115-119	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
7075153-6	1982	The rate of appearance of glucose and urea in the plasma was rapidly reduced by the 17.7 mumol min-1 kg-1 glucose infusion.	Glucose	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	95-105
7075153-6	1982	The rate of appearance of glucose and urea in the plasma was rapidly reduced by the 17.7 mumol min-1 kg-1 glucose infusion.	Urea	38-42	CD59 molecule (CD59 blood group)	Homo sapiens	95-105
7075153-6	1982	The rate of appearance of glucose and urea in the plasma was rapidly reduced by the 17.7 mumol min-1 kg-1 glucose infusion.	Glucose	106-113	CD59 molecule (CD59 blood group)	Homo sapiens	95-105
7102238-3	1982	The mean of the lowest heart rate was 44.3 beats min-1 in the atropine group compared with 54.3 beats min-1 in the glycopyrrolate group.	Atropine	62-70	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
6121576-7	1982	4 SP is almost completely absorbed and, with its metabolites, is excreted in the urine (SP renal clearance rate 32.1 ml min-1).	Sulfapyridine	2-4	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
6895893-8	1982	The second-order rate constant for inhibition of thrombin by purified HCII increases from 5.0 X 10(5) M-1 min-1 in the absence of heparin to 4.5 x 10(8) M-1 min-1 at optimal heparin concentrations of 0.8 to 1.0 unit/ml.	Heparin	174-181	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
6954552-5	1982	This rate of formation of PGE2 metabolites is very low compared to the activity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase, which was 183 +/- 19 nmol x min-1 x g of tissue-1 (n=5) when measured from the 100.000 g supernatant fraction of homogenized human placenta using 14C-PGE2 as the substrate.	Dinoprostone	26-30	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
6954552-5	1982	This rate of formation of PGE2 metabolites is very low compared to the activity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase, which was 183 +/- 19 nmol x min-1 x g of tissue-1 (n=5) when measured from the 100.000 g supernatant fraction of homogenized human placenta using 14C-PGE2 as the substrate.	14c-pge2	283-291	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
7059981-4	1982	Conversion of 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein was first-order with respect to 4-hydroxycyclophosphamide (k = 0.126 min-1 in 0.5 M phosphate buffer, pH 8, 37 degrees) as well as first-order with respect to phosphate serving as a catalyst.	4-hydroxycyclophosphamide	14-39	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
6818074-5	1982	The rates of acetone production ranged from 68 to 581 mumol/min/1.73 m2, indicating the heterogeneous nature of the patients studied.	Acetone	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
6818074-6	1982	The average acetone production rate was 265 mumol/min/1.73 m2 and accounted for about 52% of the estimated acetoacetate production rate.	Acetone	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
7068180-2	1982	In the patients with essential hypertension, the rate constant for total sodium efflux was significantly lower than in the normotensives (5.96.10(-3) +/- 0.45.10(-3) min-1 vs 6.69.10(-3) +/- 0.49.10(-3) min-1; p less than 0.005), which was due to a reduced ouabain-sensitive sodium efflux rate constant.	Sodium	73-79	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
7068180-2	1982	In the patients with essential hypertension, the rate constant for total sodium efflux was significantly lower than in the normotensives (5.96.10(-3) +/- 0.45.10(-3) min-1 vs 6.69.10(-3) +/- 0.49.10(-3) min-1; p less than 0.005), which was due to a reduced ouabain-sensitive sodium efflux rate constant.	Sodium	73-79	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
7134856-3	1982	Studies were done during infusion of 0, 3, and 9 micrograms x kg-1 x min-1 dopamine without and after an injection of domperidone, a dopamine antagonist.	Dopamine	75-83	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
7059981-4	1982	Conversion of 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein was first-order with respect to 4-hydroxycyclophosphamide (k = 0.126 min-1 in 0.5 M phosphate buffer, pH 8, 37 degrees) as well as first-order with respect to phosphate serving as a catalyst.	phosphoramide	43-56	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
7059981-4	1982	Conversion of 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein was first-order with respect to 4-hydroxycyclophosphamide (k = 0.126 min-1 in 0.5 M phosphate buffer, pH 8, 37 degrees) as well as first-order with respect to phosphate serving as a catalyst.	Acrolein	69-77	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
7059981-4	1982	Conversion of 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein was first-order with respect to 4-hydroxycyclophosphamide (k = 0.126 min-1 in 0.5 M phosphate buffer, pH 8, 37 degrees) as well as first-order with respect to phosphate serving as a catalyst.	4-hydroxycyclophosphamide	110-135	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
7059981-4	1982	Conversion of 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein was first-order with respect to 4-hydroxycyclophosphamide (k = 0.126 min-1 in 0.5 M phosphate buffer, pH 8, 37 degrees) as well as first-order with respect to phosphate serving as a catalyst.	Phosphates	162-171	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
7059981-4	1982	Conversion of 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein was first-order with respect to 4-hydroxycyclophosphamide (k = 0.126 min-1 in 0.5 M phosphate buffer, pH 8, 37 degrees) as well as first-order with respect to phosphate serving as a catalyst.	Phosphates	237-246	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
7059981-6	1982	Pseudo-first-order rate constants were 0.045 M-1 min-1 for monobasic phosphate and 0.256 M-1 min-1 for dibasic phosphate.	monobasic phosphate	59-78	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7059981-6	1982	Pseudo-first-order rate constants were 0.045 M-1 min-1 for monobasic phosphate and 0.256 M-1 min-1 for dibasic phosphate.	dibasic phosphate	103-120	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7059981-6	1982	Pseudo-first-order rate constants were 0.045 M-1 min-1 for monobasic phosphate and 0.256 M-1 min-1 for dibasic phosphate.	dibasic phosphate	103-120	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
6291881-6	1982	The Ab+ subjects required 15.0 +/- 1.9 ng isoprenaline (isoproterenol) kg-1 min-1 i.v.	Isoproterenol	42-54	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
7059415-8	1982	The renal clearance of sulphinpyrazone was approximately 18 ml min-1 and that for the sulphone was similar.	Sulfinpyrazone	23-38	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
6953738-4	1982	The plasma clearance of pethidine was significantly lower in the preoperative study (8.9 +/- 1.8 ml x kg x min-1) compared with the postoperative study (12.0 +/- 3.1 ml x kg x min-1).	Meperidine	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
6953738-4	1982	The plasma clearance of pethidine was significantly lower in the preoperative study (8.9 +/- 1.8 ml x kg x min-1) compared with the postoperative study (12.0 +/- 3.1 ml x kg x min-1).	Meperidine	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
6981913-4	1982	At the end of operation the ketanserin treated patients had significantly lower heart rate (84 +/- 16 vs. 96 +/- 14 min-1; Mean +/- S.D.	Ketanserin	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
6459738-4	1982	In patients whose fetuses were suspected of being intrauterine growth retarded, a DHEA to estrogen conversion rate constant less than or equal to 3.0 x 10(-3) min(-1) was associated with a birth weight below the tenth percentile in 60% of the pregnancies, whereas a conversion rate constant above this threshold was not associated with the same degree of growth retardation.	Dehydroepiandrosterone	82-86	CD59 molecule (CD59 blood group)	Homo sapiens	159-165
6291881-6	1982	The Ab+ subjects required 15.0 +/- 1.9 ng isoprenaline (isoproterenol) kg-1 min-1 i.v.	Isoproterenol	56-69	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
7056275-2	1982	After oral administration of a high dose of piretanide (96 mg), the pharmacokinetic parameters were: elimination rate constant 0.346 +/- 0.072 h-1, half life 2.00 +/- 0.35 h, and total plasma clearance 119.55 +/- 35.90 ml x min-1.	piretanide	44-54	CD59 molecule (CD59 blood group)	Homo sapiens	224-229
7200881-2	1982	Ventilation, gas exchange and heart rate were closely matched in all four tests in each child, with a mean oxygen consumption of 32.3 +/- 1.7 ml x min-1 x kg-1.	Oxygen	107-113	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
7084275-9	1982	Under such conditions, it seems advisable to reduce the dose to one-half only in patients with a creatinine clearance of less than 10-20 ml/min/1.73 m2.	Creatinine	97-107	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
7078105-4	1982	The affinity and phosphorylation constants, Kd and k2, for the reaction of hen brain microsomal NTE with mipafox, were found to be 6.72 x 10(-5) M and 3.23 min-1, respectively.	mipafox	105-112	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
7033265-3	1982	The infusion of cortisol (2 microgram kg-1 min-1) increased the plasma cortisol concentration approximately 4-fold (37 +/- 3 vs. 14 +/- 1 microgram/dl; P less than 0.01) to values observed during moderately severe stress in man.	Hydrocortisone	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
6797453-2	1981	Alfentanil was infused at a rate of 3.0mg min-1 until the patients (breathing pure oxygen) became unconscious.	Alfentanil	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
7318140-2	1981	Maximal oxygen uptake (2.47 +/- 0.36 l-min-1) was measured on a treadmill test.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
6751838-3	1981	Four increasing doses of terbutaline (0.036-1.23 micrograms kg-1 min-1) were thereafter administered by intravenous infusion, starting 120 min after the tablet intake.	Terbutaline	25-36	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
6459120-2	1981	Phosphorylation rates up to 90 mmol of ATP (mg of protein)-1 min-1 have been achieved.	Adenosine Triphosphate	39-42	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
7326165-7	1981	A high total body clearance of chlormethiazole (mean 1.39 litre min-1, SD 0.58) was found and would contribute to the brief duration of action after termination of the infusion.	Chlormethiazole	31-46	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
7338568-1	1981	Bumetanide was administered intravenously to four groups of patients with varying levels of glomerular filtration rate (average 10 to 108 ml/min/1.73 m2 B.S.A.).	Bumetanide	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
6792895-4	1981	Mean plasma nitroglycerin levels were maximal at 2 (1.1 +/- 0.3 ng/ml) and 5 (1.4 +/- 0.6 ng/ml) minutes, when the changes in mean heart rate (+17 +/- 7 and +12 +/- 3 min-1) and decreases in echocardiographic left ventricular diastolic (-4.2 +/- 0.8 mm at 5 minutes) and systolic (-3.1 +/- 0.6 mm at 5 minutes) dimensions were also maximal.	Nitroglycerin	12-25	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
7295486-3	1981	was present in separated epidermis (139 +/- 105 pmol glycol formed mg-1 min-1) and dermis (165 +/- 120 pmol glycol formed mg-1 microsomal protein min-1).	Glycols	53-59	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
7287864-2	1981	The mean specific activity was 0.58 +/- 0.18 nmol mevalonate formed min-1 mg-1 protein.	Mevalonic Acid	50-60	CD59 molecule (CD59 blood group)	Homo sapiens	68-78
7272661-6	1981	The net rate of lactate removal was .30 mmol.L-1.min-1.	Lactic Acid	16-23	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7284228-3	1981	Air samples could be aspirated into the collection bag at flow rates of as low as 1 ml min-1 by allowing the water to drain from the cylinder at a controlled rate.	Water	109-114	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
7028551-5	1981	The effect of tolbutamide infusion (7 mg.m-2.min-1) when compared with saline control was to increase both first phase (+54 +/- 13 mU/l, n = 8, p less than 0.001, mean +/- SEM) and second phase (+972 +/- 256 mU.	Tolbutamide	14-25	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
7261553-6	1981	Plasma clearances were significantly increased after the meal for both [14C]glycocholic acid (median 455 ml min--1 m--2, range 376--672 increased to 704, 528--1968; P less than 0.01) and indocyanine green (359, 227--473 increased to 435, 358--985; P less than 0.01).	[14c]glycocholic acid	71-92	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
7315181-4	1981	Two and 5 micrograms x kg-1 x min-1 of dopamine were infused for 30 min in two groups of five patients.	Dopamine	39-47	CD59 molecule (CD59 blood group)	Homo sapiens	30-35
7199410-9	1981	Maximal oxygen uptake was only 35 (males) and 29 (females) ml/kg min-1; this contrasted with the physical activity pattern of these patients, yet was in line with their small muscle mass with its low oxidative potential.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
7249501-4	1981	min-1 (p less than 0.001) due to increased tubular secretion of digoxin, while the glomerular filtration rate was unchanged.	Digoxin	64-71	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
7328601-1	1981	The decomposition of N-hydroxyacetaminophen has been shown to occur via an initial first-order dehydration step to N-acetyl-p-benzoquinone imine with a rate constant at pH 7.6 of 8.66 x 10(-3) min-1 and a half-life of 80 min.	N-hydroxyacetaminophen	21-43	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
7328601-1	1981	The decomposition of N-hydroxyacetaminophen has been shown to occur via an initial first-order dehydration step to N-acetyl-p-benzoquinone imine with a rate constant at pH 7.6 of 8.66 x 10(-3) min-1 and a half-life of 80 min.	N-acetyl-4-benzoquinoneimine	115-144	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
7310640-4	1981	The mean oral dose plasma clearances of prednisone ranged from 572 ml/min/1.73 m 2 for the 5 mg dose to 2271 ml/min/1.73 m 2 for the 50 mg dose.	Prednisone	40-50	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
7310640-7	1981	prednisolone was dose-dependent and increased from 111 to 194 ml/min/1.73 m 2 over the 5 to 40 mg i.v.	Prednisolone	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
7248931-3	1981	The specific activity of nicotinamide adenine dinucleotide-dependent 15-hydroxyprostaglandin dehydrogenase in hydatidiform mole tissue (0 to 1.2 nmol 15-ketoprostaglandin E2 formed x min-1 x mg-1 cytosolic protein) and in choriocarcinoma cells (1.0 nmol 15-ketoprostaglandin E2 x min-1 x mg-1 protein) was strikingly less than that found in normal placental tissue [11.4 +/- 2.3 (S.E.)	NAD	25-58	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
7248931-3	1981	The specific activity of nicotinamide adenine dinucleotide-dependent 15-hydroxyprostaglandin dehydrogenase in hydatidiform mole tissue (0 to 1.2 nmol 15-ketoprostaglandin E2 formed x min-1 x mg-1 cytosolic protein) and in choriocarcinoma cells (1.0 nmol 15-ketoprostaglandin E2 x min-1 x mg-1 protein) was strikingly less than that found in normal placental tissue [11.4 +/- 2.3 (S.E.)	NAD	25-58	CD59 molecule (CD59 blood group)	Homo sapiens	280-285
7248931-3	1981	The specific activity of nicotinamide adenine dinucleotide-dependent 15-hydroxyprostaglandin dehydrogenase in hydatidiform mole tissue (0 to 1.2 nmol 15-ketoprostaglandin E2 formed x min-1 x mg-1 cytosolic protein) and in choriocarcinoma cells (1.0 nmol 15-ketoprostaglandin E2 x min-1 x mg-1 protein) was strikingly less than that found in normal placental tissue [11.4 +/- 2.3 (S.E.)	15-ketoprostaglandin E2	150-173	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
7248931-4	1981	nmol 15-ketoprostaglandin x min-1 x mg-1 protein].	15-ketoprostaglandin	5-25	CD59 molecule (CD59 blood group)	Homo sapiens	28-33
6787388-6	1981	min-1 with a rise in alanine concentration from 0.96 +/- 0.17 mgatC .	Alanine	21-28	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6787388-6	1981	min-1 with a rise in alanine concentration from 0.96 +/- 0.17 mgatC .	mgatc	62-67	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
6787388-10	1981	min-1 with a lowering of alanine concentration to 1.44 +/- 0.22 mgatC .	Alanine	25-32	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
7293923-6	1981	For an inspiratory flow rate of 30 L min-1, the total deposition efficiency of H2SO4-and-H2O droplets, resulting from water condensation upon H2SO4 particles of initial geometric diameter D0, is greater than inspired nonhygroscopic particles of identical aerodynamic diameter when D0 greater than 0.1 mu m. The opposite is found when D0 less than 0.1 mu m. The effects of hygroscopic growth are explained in terms of the changing deposition efficiencies of the inertial impaction, sedimentation and diffusion mechanisms.	sulfuric acid	79-84	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
7293923-6	1981	For an inspiratory flow rate of 30 L min-1, the total deposition efficiency of H2SO4-and-H2O droplets, resulting from water condensation upon H2SO4 particles of initial geometric diameter D0, is greater than inspired nonhygroscopic particles of identical aerodynamic diameter when D0 greater than 0.1 mu m. The opposite is found when D0 less than 0.1 mu m. The effects of hygroscopic growth are explained in terms of the changing deposition efficiencies of the inertial impaction, sedimentation and diffusion mechanisms.	Water	89-92	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
7293923-6	1981	For an inspiratory flow rate of 30 L min-1, the total deposition efficiency of H2SO4-and-H2O droplets, resulting from water condensation upon H2SO4 particles of initial geometric diameter D0, is greater than inspired nonhygroscopic particles of identical aerodynamic diameter when D0 greater than 0.1 mu m. The opposite is found when D0 less than 0.1 mu m. The effects of hygroscopic growth are explained in terms of the changing deposition efficiencies of the inertial impaction, sedimentation and diffusion mechanisms.	Water	118-123	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
7293923-6	1981	For an inspiratory flow rate of 30 L min-1, the total deposition efficiency of H2SO4-and-H2O droplets, resulting from water condensation upon H2SO4 particles of initial geometric diameter D0, is greater than inspired nonhygroscopic particles of identical aerodynamic diameter when D0 greater than 0.1 mu m. The opposite is found when D0 less than 0.1 mu m. The effects of hygroscopic growth are explained in terms of the changing deposition efficiencies of the inertial impaction, sedimentation and diffusion mechanisms.	d0	188-190	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
7235917-6	1981	The energy cost (oxygen consumption) VO2.wt-1 (ml.min-1.kg-1) of ambulating with underarm crutches compared to normal walking was approximately twice as great.	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
6790281-3	1981	Glucose is utilized at a rate of 1.1 mumol x min-1 x g cells-1.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
6790281-12	1981	Pyruvate is decarboxylated at a rate of 66 nmol x min-1 x g cells-1, 45-80% of it is incorporated into lipids instead of being oxidized, depending on the incubation conditions.	Pyruvic Acid	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
6790281-18	1981	Leucine utilization, 28 nmol x min-1 x g cells-1, is very high compared with normal cells, due to the high rate of lipid and protein synthesis.	Leucine	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
7338607-4	1981	Mean transfer rates of 150, 0.023 and 0.034 mumol min-1 were obtained for [14C] antipyrine, [3H] palmitic and [14C] linoleic acids, respectively.	14c] antipyrine	75-90	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
7338607-4	1981	Mean transfer rates of 150, 0.023 and 0.034 mumol min-1 were obtained for [14C] antipyrine, [3H] palmitic and [14C] linoleic acids, respectively.	Tritium	93-95	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
7338607-4	1981	Mean transfer rates of 150, 0.023 and 0.034 mumol min-1 were obtained for [14C] antipyrine, [3H] palmitic and [14C] linoleic acids, respectively.	Linoleic Acids	116-130	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
7333740-6	1981	Oxygen uptake and heart rate were relatively constant for each subject and averaged 0.94 l x min-1 and 110 beat x min-1 throughout exercise.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
7333740-6	1981	Oxygen uptake and heart rate were relatively constant for each subject and averaged 0.94 l x min-1 and 110 beat x min-1 throughout exercise.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
7195567-9	1981	min-1, the Qc value, calculated exclusively from acetylene concentrations recorded during rebreathing, was multiplied by the above-mentioned VO2-ratio.	Acetylene	49-58	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
7243377-2	1981	Increased quantities of hydrogen peroxide were released into the extracellular culture media by nonphagocytic neutrophils from infants (0.25 nM/min/2.5 x 10(6) neutrophils compared to 0.14 for controls), a condition that could promote autooxidation because infant neutrophils are deficient in glutathione peroxidase and catalase (enzymes that detoxify hydrogen peroxide).	Hydrogen Peroxide	24-41	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
6788125-7	1981	Haemoglobin concentration was strongly correlated with creatinine clearance (r=0.70), particularly with clearances below 100 ml/min/1.73 m2 (r=0.96; p less than 0.001).	Creatinine	55-65	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
7225267-3	1981	The minimum infusion rate (MIR) was found to be 11.3 micrograms kg-1 min-1 for patients premedicated with morphine 10 mg i.m.	Morphine	106-114	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
7238507-7	1981	V for cyclohexaamylase was found to be about 14-15 mumol glucose min-1 (mg pure protein)-1, the Km for cyclohexaamylose was 0.142 mM.	Glucose	57-64	CD59 molecule (CD59 blood group)	Homo sapiens	65-90
7238507-7	1981	V for cyclohexaamylase was found to be about 14-15 mumol glucose min-1 (mg pure protein)-1, the Km for cyclohexaamylose was 0.142 mM.	alpha-cyclodextrin	103-119	CD59 molecule (CD59 blood group)	Homo sapiens	65-90
7211731-5	1981	On discontinuing ascorbic acid administration, oxalate excretion returned to baseline values within 24 h. The time-course of oxalate excretion revealed that following the 3rd dose of 2 g ascorbic acid a plateau in urinary oxalate excretion was reached (0.6 microgram ml-1 min-1) which was not exceeded despite additional 2-g doses of ascorbic acid.	Ascorbic Acid	187-200	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
7211731-5	1981	On discontinuing ascorbic acid administration, oxalate excretion returned to baseline values within 24 h. The time-course of oxalate excretion revealed that following the 3rd dose of 2 g ascorbic acid a plateau in urinary oxalate excretion was reached (0.6 microgram ml-1 min-1) which was not exceeded despite additional 2-g doses of ascorbic acid.	Ascorbic Acid	187-200	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
6113195-4	1981	Kinetic analysis of (3H) isoproterenol binding provided a value of 2.01 x 10(4) min-1.	(3h) isoproterenol	20-38	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
6113195-6	1981	Dissociation of (3H) isoproterenol was a first order reaction with a rate constant, k2, of 0.62 x 10(-1) min-1.	(3h) isoproterenol	16-34	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
6259595-6	1981	With microbiological assay, the elimination serum half-life (T 1/2) increased in patients according to their degree of renal insufficiency and reached 10 hours when creatinine clearance fell below 10 ml.min-1.	Creatinine	165-175	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
6259595-8	1981	Cefotaxime can be administered at a dose of 1 g i.v., twice daily in patients with stable chronic renal insufficiency when creatinine clearance is above 5 ml min-1.	Cefotaxime	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
30836550-4	1981	Hydrolysis constants ranged from &lt;0.001 min-1 in the gastric juice to 0.064 min-1 for the linoleate ester in the pancreatic juice.	linoleate ester	93-108	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
7308272-5	1981	Following i. v. injection, the concentration of lisuride declined in three phases, with half-lives of 5 min, 25 min and 2 h. The total plasma clearance of 800 +/- 250 ml X min-1 was in the range of "plasma flow" through the liver.	Lisuride	48-56	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
7310854-3	1981	The pseudo-first-order rate constant for the complex with a substrate analog, di-n-butylaminoethanol, is found to be nearly double that for the free carrier, showing that the carrier conformation is altered following addition of a ligand (with 1 mM N-ethylmaleimide at pH 6.8, 37 degree C, the constants are 0.57 +/- 0.05 min-1 and 0.33 +/- 0.02 min-1, respectively).	di-n-butylaminoethanol	78-100	CD59 molecule (CD59 blood group)	Homo sapiens	322-327
7310854-3	1981	The pseudo-first-order rate constant for the complex with a substrate analog, di-n-butylaminoethanol, is found to be nearly double that for the free carrier, showing that the carrier conformation is altered following addition of a ligand (with 1 mM N-ethylmaleimide at pH 6.8, 37 degree C, the constants are 0.57 +/- 0.05 min-1 and 0.33 +/- 0.02 min-1, respectively).	di-n-butylaminoethanol	78-100	CD59 molecule (CD59 blood group)	Homo sapiens	346-351
6258679-2	1980	The preparation was capable of an oxalate-stimulated Ca2+ uptake at a mean rate of 0.74 nmol Ca2+ mg-1 protein min-1 which could be inhibited by a Ca2+ ionophore, A 23 187, and by Tween 80.	Oxalates	34-41	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
6258679-2	1980	The preparation was capable of an oxalate-stimulated Ca2+ uptake at a mean rate of 0.74 nmol Ca2+ mg-1 protein min-1 which could be inhibited by a Ca2+ ionophore, A 23 187, and by Tween 80.	Polysorbates	180-188	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
6257522-5	1980	A lower limit of 0.15 min-1 for the binding rate constant in the uninhibited gland was estimated from the observations in one subject who demonstrated a small perchlorate discharge.	perchlorate	159-170	CD59 molecule (CD59 blood group)	Homo sapiens	22-27
6265626-2	1980	Noradrenaline was infused into normal resting male subjects for consecutive 20 min periods at 3, 7.5 and 15 microgram min-1.	Norepinephrine	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
7208153-7	1980	of 34.48 +/- 11.59 and 12.65 +/- 5.60 mumole butyric acid min-1 ml-1, respectively.	Butyric Acid	45-57	CD59 molecule (CD59 blood group)	Homo sapiens	58-68
6784978-5	1980	min-1) completely abolished the naloxone effect on gonadotrophin release.	Naloxone	32-40	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
7448106-5	1980	values of lignocaine clearance (ml min-1 kg-1) were higher in patients without heart failure (11.8 +/- 2.6, n = 9) than in those with heart failure (7.2 +/- 1.9, n = 9) (P &lt; 0002).	Lidocaine	10-20	CD59 molecule (CD59 blood group)	Homo sapiens	35-45
7439245-1	1980	The urinary excretion rate of D-glucaric acid, an in vivo parameter of the activity of drug metabolizing enzymes, has been determined in patients with chronic renal insufficiency (glomerular filtration rate 4.5-80 ml/min/1.73m2).	Glucaric Acid	30-45	CD59 molecule (CD59 blood group)	Homo sapiens	217-222
7410388-2	1980	the rdical was found to be reoxidized readily by molecular oxygen, with a rate constant of 4 x 10(5) M-1 min-1 at pH 7.0, 25 degrees C. On mixing the radical under anaerobic conditions with pyruvate, a change in spectrum typical of charge transfer interaction was found.	Oxygen	59-65	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
7410388-2	1980	the rdical was found to be reoxidized readily by molecular oxygen, with a rate constant of 4 x 10(5) M-1 min-1 at pH 7.0, 25 degrees C. On mixing the radical under anaerobic conditions with pyruvate, a change in spectrum typical of charge transfer interaction was found.	Pyruvic Acid	190-198	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
6905639-4	1980	The bimolecular velocity constant for the inhibition by diisopropyl fluorophosphate was determined as 9 +/- 2 1 mol-1 min-1.	Isoflurophate	56-83	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
7435577-7	1980	Fetal oxygen consumption increased 28% to 10.5 +/- 0.5 from 8.2 +/- 1.1 ml x min-1 x kg-1.	Oxygen	6-12	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
6776974-3	1980	The low-flow system delivered 2 litre min-1 of dry oxygen into the nasopharynx through a catheter.	Oxygen	51-57	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
7467586-2	1980	The application of thiazides, which possess a long-term effect, is indicated only up to a value of the creatinine clearance of about 25 ml/min/1.73 m2.	Thiazides	19-28	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
7467586-2	1980	The application of thiazides, which possess a long-term effect, is indicated only up to a value of the creatinine clearance of about 25 ml/min/1.73 m2.	Creatinine	103-113	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
6105392-1	1980	When prostacyclin (5 ng kg-1 min-1) was given during dialysis it enhanced the biological activity of heparin and prevented the activation and consumption of platelets.	Epoprostenol	5-17	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
6105392-1	1980	When prostacyclin (5 ng kg-1 min-1) was given during dialysis it enhanced the biological activity of heparin and prevented the activation and consumption of platelets.	Heparin	101-108	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
7400003-2	1980	Means +/- SD of five weekly measurements in eight hamsters were 0.68 +/- 0.09 ml for tidal volume, 45 +/- 14 breaths.min-1 for respiratory frequency, 29.3 +/- 10.4 ml.min-1 for minute ventilation, 0.301 +/- 0.080 ml.cmH2O-1 for dynamic compliance, 0.435 +/- 0.151 cmH2O.ml-1.s for inspiratory resistance, 0.311 +/- 0.101 cmH2O.ml-1.s for expiratory resistance, and 0.334 +/- 0.096 cmH2O.ml-1.s for average resistance.	cmh2o	216-221	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
7400003-2	1980	Means +/- SD of five weekly measurements in eight hamsters were 0.68 +/- 0.09 ml for tidal volume, 45 +/- 14 breaths.min-1 for respiratory frequency, 29.3 +/- 10.4 ml.min-1 for minute ventilation, 0.301 +/- 0.080 ml.cmH2O-1 for dynamic compliance, 0.435 +/- 0.151 cmH2O.ml-1.s for inspiratory resistance, 0.311 +/- 0.101 cmH2O.ml-1.s for expiratory resistance, and 0.334 +/- 0.096 cmH2O.ml-1.s for average resistance.	cmh2o	264-269	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
7400003-2	1980	Means +/- SD of five weekly measurements in eight hamsters were 0.68 +/- 0.09 ml for tidal volume, 45 +/- 14 breaths.min-1 for respiratory frequency, 29.3 +/- 10.4 ml.min-1 for minute ventilation, 0.301 +/- 0.080 ml.cmH2O-1 for dynamic compliance, 0.435 +/- 0.151 cmH2O.ml-1.s for inspiratory resistance, 0.311 +/- 0.101 cmH2O.ml-1.s for expiratory resistance, and 0.334 +/- 0.096 cmH2O.ml-1.s for average resistance.	cmh2o	264-269	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
6157632-8	1980	The bimolecular velocity constant for the inhibition by diisopropyl fluorophosphate was determined as 9 +/- 2l x mol-1 x min-1.	Isoflurophate	56-83	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
7000717-12	1980	The interaction of metoprolol with the effect of adrenaline (0.09 microgram x kg-1 x min-1, infused at 2, 3.5 and 5 hrs after metoprolol administration) on the diastolic blood pressure was more pronounced when two ordinary 0.1 g metoprolol tablets were administered once daily than for the corresponding dose in Durules, this probably reflecting a difference in degree of action of metoprolol on the vascular bed for Durules and regular metoprolol tablets in identical doses.	Metoprolol	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
6995479-5	1980	At steady-state plasma epinephrine concentrations of 24-74 pg/ml, values overlapping the basal normal range, the mean (+/-SE) plasma metabolic clearance rate of epinephrine was 52 +/- 4 ml x min-1 x kg-1; this value rose to 89 +/- 6 ml x min-1 x kg-1 (P less than 0.01) at steady-state epinephrine concentrations of 90-1,020 pg/ml.	Epinephrine	161-172	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
6995479-5	1980	At steady-state plasma epinephrine concentrations of 24-74 pg/ml, values overlapping the basal normal range, the mean (+/-SE) plasma metabolic clearance rate of epinephrine was 52 +/- 4 ml x min-1 x kg-1; this value rose to 89 +/- 6 ml x min-1 x kg-1 (P less than 0.01) at steady-state epinephrine concentrations of 90-1,020 pg/ml.	Epinephrine	161-172	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
7441528-4	1980	The resting rate constant of phosphate efflux was 2.61 X 10(-3) min-1: electrical stimulation (10 sec-1, 3 min) produced an extra fractional loss of 6.75 X 10(-6) impulse-1.	Phosphates	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
7441530-3	1980	In solutions with 2 mM-phosphate and 1 mM-K the rate constant of the resting efflux was 2.7 x 10(-3) min(-1); stimulation caused an extra fractional loss of 2.8 x 10(-6) impulse(-1).3.	Phosphates	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
7441530-4	1980	Lowering the phosphate concentration decreased the resting and the stimulated efflux; with 0.2 mM-phosphate the corresponding values were 1.9 x 10(-3) min(-1) and 1.8 x 10(-6) impulse(-1), respectively.4.	Phosphates	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	151-157
7441530-4	1980	Lowering the phosphate concentration decreased the resting and the stimulated efflux; with 0.2 mM-phosphate the corresponding values were 1.9 x 10(-3) min(-1) and 1.8 x 10(-6) impulse(-1), respectively.4.	Phosphates	98-107	CD59 molecule (CD59 blood group)	Homo sapiens	151-157
6769917-4	1980	The covalent NO2dUMPenzyme complex is sufficiently stable to permit isolation on nitrocellulose membranes, and dissociates to give unchanged NO2-dUMP with a first order rate constant of 8.9 x 10(-3) min-1.	no2dumpenzyme	13-26	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
6769917-4	1980	The covalent NO2dUMPenzyme complex is sufficiently stable to permit isolation on nitrocellulose membranes, and dissociates to give unchanged NO2-dUMP with a first order rate constant of 8.9 x 10(-3) min-1.	no2-dump	141-149	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
6769344-2	1980	A three-compartment explanatory model was used to derive fractional rate constants for the forward flux of L-dopa into the endothelium of the brain capillaries from the blood (1.54 +/- 0.37 min-1), the back flux of dopa and/or its metabolites to the blood from the endothelium (0.67 +/- 0.05 min-1), the formation of dopamine from dopa (0.20 +/- 0.04 min-1), and the destruction of dopamine (0.04 +/- 0.02 min-1).	Levodopa	107-113	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
6769567-7	1980	For prolonged infusions we found that nitroprusside at 1 microgram.kg-1.min-1 and nitroglycerin at 0.5 microgram.kg-1.min-1 were without significant toxicity.	Nitroprusside	38-51	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
6769567-7	1980	For prolonged infusions we found that nitroprusside at 1 microgram.kg-1.min-1 and nitroglycerin at 0.5 microgram.kg-1.min-1 were without significant toxicity.	Nitroglycerin	82-95	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
6769344-2	1980	A three-compartment explanatory model was used to derive fractional rate constants for the forward flux of L-dopa into the endothelium of the brain capillaries from the blood (1.54 +/- 0.37 min-1), the back flux of dopa and/or its metabolites to the blood from the endothelium (0.67 +/- 0.05 min-1), the formation of dopamine from dopa (0.20 +/- 0.04 min-1), and the destruction of dopamine (0.04 +/- 0.02 min-1).	Levodopa	107-113	CD59 molecule (CD59 blood group)	Homo sapiens	292-297
6769344-2	1980	A three-compartment explanatory model was used to derive fractional rate constants for the forward flux of L-dopa into the endothelium of the brain capillaries from the blood (1.54 +/- 0.37 min-1), the back flux of dopa and/or its metabolites to the blood from the endothelium (0.67 +/- 0.05 min-1), the formation of dopamine from dopa (0.20 +/- 0.04 min-1), and the destruction of dopamine (0.04 +/- 0.02 min-1).	Levodopa	107-113	CD59 molecule (CD59 blood group)	Homo sapiens	292-297
6769344-2	1980	A three-compartment explanatory model was used to derive fractional rate constants for the forward flux of L-dopa into the endothelium of the brain capillaries from the blood (1.54 +/- 0.37 min-1), the back flux of dopa and/or its metabolites to the blood from the endothelium (0.67 +/- 0.05 min-1), the formation of dopamine from dopa (0.20 +/- 0.04 min-1), and the destruction of dopamine (0.04 +/- 0.02 min-1).	Levodopa	107-113	CD59 molecule (CD59 blood group)	Homo sapiens	292-297
6769344-2	1980	A three-compartment explanatory model was used to derive fractional rate constants for the forward flux of L-dopa into the endothelium of the brain capillaries from the blood (1.54 +/- 0.37 min-1), the back flux of dopa and/or its metabolites to the blood from the endothelium (0.67 +/- 0.05 min-1), the formation of dopamine from dopa (0.20 +/- 0.04 min-1), and the destruction of dopamine (0.04 +/- 0.02 min-1).	Dihydroxyphenylalanine	109-113	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
7418714-5	1980	This was reflected in a mean clearance value after the 100 mg dose of 31 +/- 16 (SD ml x min(-1) compared with a mean clearance of 62 +/- 19 ml x min(-1) following injection of 25 mg methotrexate.	Methotrexate	183-195	CD59 molecule (CD59 blood group)	Homo sapiens	146-152
7418714-6	1980	Renal clearance of methotrexate was markedly lower following the 100 mg dose (18 +/- 6 ml x min(-1) than after 25 mg (53 +/- 19 ml x min(-1).	Methotrexate	19-31	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
7418714-6	1980	Renal clearance of methotrexate was markedly lower following the 100 mg dose (18 +/- 6 ml x min(-1) than after 25 mg (53 +/- 19 ml x min(-1).	Methotrexate	19-31	CD59 molecule (CD59 blood group)	Homo sapiens	133-139
7052338-1	1980	1 The effects of adrenoceptor blocking drugs on the metabolic responses to adrenaline infusion (1 microgram kg-1 min-1) have been studied in the anaesthetized, fasted cat.	Epinephrine	75-85	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
7392899-4	1980	Maximum oxygen consumption averaged 45.2 ml/kg min-1 when the subjects were considered as a single group.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
7052338-3	1980	3 Phentolamine infusion, at a rate (15 micrograms kg-1 min-1 after a priming dose of 2.5 mg/kg) which reversed the pressor effect of adrenaline, reduced but did not abolish adrenaline-induced hyperglycaemia.	Phentolamine	2-14	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
7052338-3	1980	3 Phentolamine infusion, at a rate (15 micrograms kg-1 min-1 after a priming dose of 2.5 mg/kg) which reversed the pressor effect of adrenaline, reduced but did not abolish adrenaline-induced hyperglycaemia.	Epinephrine	133-143	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
7052338-4	1980	4 The continuous infusion of a combination of phentolamine (15 micrograms kg-1 min-1 after a priming dose of 2.5 mg/kg) and propranolol (5 micrograms kg-1 min-1 after a priming dose of 0.25 mg/kg) prevented completely the hyperglycaemia response to adrenaline infusion over a 6 h period.	Phentolamine	46-58	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
7378935-4	1980	Alcohol intoxication in conjunction with cold water immersion caused a further large increase in urine flow to 8.03 mL min-1.	Alcohols	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
6243476-3	1980	In the presence of NaSCN, the dissociation rate of the complex increases about 10-fold (K-1 SCN = 1.10 x 10(-2) min-1 vs. K-1 = 1.07 X 10 (-3)min-1) while the rate of association increases about 2-fold (K1 SCN = 1.2 X 10(7) min-1M-1 vs.K1= 7.4 X 10(6) min-1 M-1).	sodium thiocyanate	19-24	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
7378935-4	1980	Alcohol intoxication in conjunction with cold water immersion caused a further large increase in urine flow to 8.03 mL min-1.	Water	46-51	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
6243476-3	1980	In the presence of NaSCN, the dissociation rate of the complex increases about 10-fold (K-1 SCN = 1.10 x 10(-2) min-1 vs. K-1 = 1.07 X 10 (-3)min-1) while the rate of association increases about 2-fold (K1 SCN = 1.2 X 10(7) min-1M-1 vs.K1= 7.4 X 10(6) min-1 M-1).	sodium thiocyanate	19-24	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
6243476-3	1980	In the presence of NaSCN, the dissociation rate of the complex increases about 10-fold (K-1 SCN = 1.10 x 10(-2) min-1 vs. K-1 = 1.07 X 10 (-3)min-1) while the rate of association increases about 2-fold (K1 SCN = 1.2 X 10(7) min-1M-1 vs.K1= 7.4 X 10(6) min-1 M-1).	sodium thiocyanate	19-24	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
7448340-4	1980	Below 40 ml min-1 a linear relationship existed between beta and Clcr.	(2-benzoylethyl)trimethylammonium	56-60	CD59 molecule (CD59 blood group)	Homo sapiens	12-17
7448340-4	1980	Below 40 ml min-1 a linear relationship existed between beta and Clcr.	clcr	65-69	CD59 molecule (CD59 blood group)	Homo sapiens	12-17
7448340-5	1980	Similarly, the plasma elimination half-life (t 1/2 beta) showed a significant increase when the Clcr was less than 30 ml min-1.	clcr	96-100	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
7448340-8	1980	Therefore, in patients with Clcr less than 40 ml min-1 both the loading and maintenance dose of disopyramide should be reduced.	clcr	28-32	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
7448340-8	1980	Therefore, in patients with Clcr less than 40 ml min-1 both the loading and maintenance dose of disopyramide should be reduced.	Disopyramide	96-108	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
159303-2	1979	At 21 degrees C, in the presence of 2 mM MgCl2 and 5 microM [gamma-32P]ATP there was a rapid phosphorylation of the enzyme with a pseudofirst order rate constant of 1400 min-1.	Magnesium Chloride	41-46	CD59 molecule (CD59 blood group)	Homo sapiens	170-175
7433905-1	1980	In the anesthetized cat duodenal perfusion with Na-taurocholate (TC, 0.2 M, pH 6.1, 290 mosmol, 45 ml x h-1) stimulated pancreatic volume (0 to 326 +/- 236 mg x 10 min-1) and bicarbonate secretion (0 to 34.2 +/- 4.1 mumol x 10 min-1), whereas pancreatic enzyme output was sparse.	sodium taurocholate	48-63	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
7433905-1	1980	In the anesthetized cat duodenal perfusion with Na-taurocholate (TC, 0.2 M, pH 6.1, 290 mosmol, 45 ml x h-1) stimulated pancreatic volume (0 to 326 +/- 236 mg x 10 min-1) and bicarbonate secretion (0 to 34.2 +/- 4.1 mumol x 10 min-1), whereas pancreatic enzyme output was sparse.	sodium taurocholate	48-63	CD59 molecule (CD59 blood group)	Homo sapiens	227-232
159303-2	1979	At 21 degrees C, in the presence of 2 mM MgCl2 and 5 microM [gamma-32P]ATP there was a rapid phosphorylation of the enzyme with a pseudofirst order rate constant of 1400 min-1.	[gamma-32p]atp	60-74	CD59 molecule (CD59 blood group)	Homo sapiens	170-175
159303-3	1979	Addition of the ATP about 120 ms before the MgCl2 increased this rate constant to 4400 min-1.	Adenosine Triphosphate	16-19	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
159303-3	1979	Addition of the ATP about 120 ms before the MgCl2 increased this rate constant to 4400 min-1.	Magnesium Chloride	44-49	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
159303-5	1979	Addition of 4 or 10 mM KCl to the phosphoenzyme which had been formed in the absence of KCl produced a rapid initial rate of dephosphorylation (k = 2600 and 3200 min-1 respectively).	Potassium Chloride	23-26	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
159303-5	1979	Addition of 4 or 10 mM KCl to the phosphoenzyme which had been formed in the absence of KCl produced a rapid initial rate of dephosphorylation (k = 2600 and 3200 min-1 respectively).	Potassium Chloride	88-91	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
159303-6	1979	An additional slow component of dephosphorylation was observed when unlabeled ATP was added together with the KCl (k = 700 to 900 min-1).	Adenosine Triphosphate	78-81	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
159303-6	1979	An additional slow component of dephosphorylation was observed when unlabeled ATP was added together with the KCl (k = 700 to 900 min-1).	Potassium Chloride	110-113	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
396063-2	1979	The haemodynamic response to antagonistic (10 microgram min-1 kg-1) and agonistic (40 microgram min-1 kg-1) doses of saralasin was studied in young essential hypertensive patients.	Saralasin	117-126	CD59 molecule (CD59 blood group)	Homo sapiens	96-106
260927-4	1979	The bimolecular velocity constant for the inhibition by diisopropyl fluorophosphate was determined as 4 l x mol-1 x min-1.	Isoflurophate	56-83	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
119844-17	1979	In perfused glands, ligation of the submandibular duct for 3--12 days reduced permeability-surface area (ml.min-1.g-1) for [51Cr]EDTA from 5.26 +/- 0.60 (mean +/- S.E., n = 9) to 4.20 +/- 0.12 (n = 4, P less than 0.30), [57Co]cyanocobalamin from 3.22 +/- 0.12 (n = 48) to 2.02 +/- 0.08 (n = 15, P less than 0.001) and [125I]insulin from 1.52 +/- 0.07 (n = 39) to 0.72 +/- 0.23 (n = 11, P less than 0.001).	Edetic Acid	129-133	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
227300-6	1979	Sequential creatinine clearances were reduced to 74 to 90 mL/min.1.73 m2 in five patients for the duration of follow-up.	Creatinine	11-21	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
117821-3	1979	Dopamine 8 micrograms kg-1 min-1 alone produced a marked increase of the cardiac index from 2.47 to 3.47 litre min-1 m-2 but only small changes in heart rate (from 65 to 68 beat min-1).	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
117821-3	1979	Dopamine 8 micrograms kg-1 min-1 alone produced a marked increase of the cardiac index from 2.47 to 3.47 litre min-1 m-2 but only small changes in heart rate (from 65 to 68 beat min-1).	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
117821-3	1979	Dopamine 8 micrograms kg-1 min-1 alone produced a marked increase of the cardiac index from 2.47 to 3.47 litre min-1 m-2 but only small changes in heart rate (from 65 to 68 beat min-1).	Dopamine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
552861-2	1979	In the first two hours after injection renal clearance had a mean value of 89.0 ml min-1 and fell to 29.4 ml min-1 between 48 and 72 h. In a separate study disopyramide was given by continuous intravenous (i.v.)	Disopyramide	156-168	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
479182-1	1979	Acetohydroxamic acid reacts with the enzyme-CoA form of succinyl-CoA:3-ketoacid coenzyme A transferase to give an inactive product with a rate constant of 860 M-1 min-1 at pH 8.1, 25 degrees C. The reaction is reversible in the presence of coenzyme A and has an equilibrium constant of 0.040.	acetohydroxamic acid	0-20	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
508978-6	1979	min-1, below which oxygen consumption falls dramatically.	Oxygen	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
512942-10	1979	The addition of leucine (10 mM) to the lumen of the intestine preloaded with alpha MG approximately halves the rate constant for alpha MG washout into the blood from 12.6 +/- 1.7 (4) x 10(-3) to 5.5 +/- 1.4 (4) x 10(-3) min-1, without appreciably altering the pool of monosaccharide in the tissue.	Leucine	16-23	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
222752-8	1979	min-1 mg-1 for the threonine- and serine-containing peptides, respectively.	Threonine	19-28	CD59 molecule (CD59 blood group)	Homo sapiens	0-10
222752-8	1979	min-1 mg-1 for the threonine- and serine-containing peptides, respectively.	Serine	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	0-10
222752-8	1979	min-1 mg-1 for the threonine- and serine-containing peptides, respectively.	Peptides	52-60	CD59 molecule (CD59 blood group)	Homo sapiens	0-10
476104-3	1979	0.9 nmol.mg-1 protein.min-1), [Ca2+]1/2 is 0.18 microM, [ATP]1/2 is 30--60 microM, the Ca2+ uptake rate depends on [Ca2+]2 and the dependence of uptake rate on ATP concentration implies strong ATP-ATP cooperativity.	Adenosine Triphosphate	57-60	CD59 molecule (CD59 blood group)	Homo sapiens	22-27
476104-3	1979	0.9 nmol.mg-1 protein.min-1), [Ca2+]1/2 is 0.18 microM, [ATP]1/2 is 30--60 microM, the Ca2+ uptake rate depends on [Ca2+]2 and the dependence of uptake rate on ATP concentration implies strong ATP-ATP cooperativity.	Adenosine Triphosphate	160-163	CD59 molecule (CD59 blood group)	Homo sapiens	22-27
476104-3	1979	0.9 nmol.mg-1 protein.min-1), [Ca2+]1/2 is 0.18 microM, [ATP]1/2 is 30--60 microM, the Ca2+ uptake rate depends on [Ca2+]2 and the dependence of uptake rate on ATP concentration implies strong ATP-ATP cooperativity.	Adenosine Triphosphate	160-163	CD59 molecule (CD59 blood group)	Homo sapiens	22-27
476104-3	1979	0.9 nmol.mg-1 protein.min-1), [Ca2+]1/2 is 0.18 microM, [ATP]1/2 is 30--60 microM, the Ca2+ uptake rate depends on [Ca2+]2 and the dependence of uptake rate on ATP concentration implies strong ATP-ATP cooperativity.	Adenosine Triphosphate	160-163	CD59 molecule (CD59 blood group)	Homo sapiens	22-27
468645-4	1979	The step-response time for the described system including a Beckman LB-2 CO2 analyzer, sampling tubing, and dryer is 120 ms at 1 l.min-1.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	73-76	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
456773-3	1979	The rates of appearance of glucose and of free fatty acids were increased in the diabetics to 17.6 and 10.2 micronmol min-1 kg-1 respectively.	Glucose	27-34	CD59 molecule (CD59 blood group)	Homo sapiens	118-128
456773-3	1979	The rates of appearance of glucose and of free fatty acids were increased in the diabetics to 17.6 and 10.2 micronmol min-1 kg-1 respectively.	Fatty Acids, Nonesterified	42-58	CD59 molecule (CD59 blood group)	Homo sapiens	118-128
224188-3	1979	Kinetic measurements of the soluble enzyme showed two apparent Km values for low and high cAMP concentrations, i.e. 4.5 and 100 micro M with Vmax values of 0.25 and 2.0 nmol cAMP hydrolysed min-1 mg protein-1.	Cyclic AMP	90-94	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
224188-3	1979	Kinetic measurements of the soluble enzyme showed two apparent Km values for low and high cAMP concentrations, i.e. 4.5 and 100 micro M with Vmax values of 0.25 and 2.0 nmol cAMP hydrolysed min-1 mg protein-1.	Cyclic AMP	174-178	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
224188-4	1979	The bound enzyme had an apparent Km of 66.6 microM with a Vmax of 0.75 nmol cAMP hydrolysed min-1 mg protein-1.	Cyclic AMP	76-80	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
761446-9	1979	In 7 normal subjects, the (mean +/- SD) rate constant for equilibration of dTC effect (paralysis) and Cp is 0.13 +/- 0.04 min-1 and the (mean +/- SD) steady-state Cp required to produce 50% paralysis is 0.37 +/- 0.05 microgram/ml.	Tubocurarine	75-78	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
33536-4	1979	Injections of small doses (0.02 to 0.4 microg kg-1 min-1) of isoprenaline induced the same pattern of changes in the FECG as we have previously recorded during hypoxia.	Isoproterenol	61-73	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
284720-2	1979	The average biological half-life after oral administration of 1 g paracetamol was significantly prolonged in patients with hepatic cirrhosis compared to the controls (3.7 hr vs.2.1 hr) and, correspondingly, the average  plasma clearance was significantly reduced from 337 ml x min-1 in the controls to 162 ml x min-1 in the patients with cirrhosis of the liver.	Acetaminophen	66-77	CD59 molecule (CD59 blood group)	Homo sapiens	277-282
284720-2	1979	The average biological half-life after oral administration of 1 g paracetamol was significantly prolonged in patients with hepatic cirrhosis compared to the controls (3.7 hr vs.2.1 hr) and, correspondingly, the average  plasma clearance was significantly reduced from 337 ml x min-1 in the controls to 162 ml x min-1 in the patients with cirrhosis of the liver.	Acetaminophen	66-77	CD59 molecule (CD59 blood group)	Homo sapiens	311-316
231460-5	1979	The enzyme shows a strong affinity for glucose-6-phosphate (Km = 2.5 mM, VM = 220 nmoles.min-1mg-1).	Glucose-6-Phosphate	39-58	CD59 molecule (CD59 blood group)	Homo sapiens	89-98
37878-2	1979	2 The amount of nadolol excreted during the 120-h period after receiving the drug ranged from less than 1% in functionally anephric, patients up to 11.5% in patients with average creatinine clearance of 57.9 +/- 3.6 ml/min/1.73 m2.	Nadolol	16-23	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
391257-3	1979	3 Phenytoin clearance was markedly increased in presence of valproic acid as compared to control values (0.52 +/- 0.17 v 0.38 +/- 0.11 ml min-1 kg-1 respectively, P less than 0.02).	Valproic Acid	60-73	CD59 molecule (CD59 blood group)	Homo sapiens	138-148
120040-3	1979	The activity was characterized by an optimal pH between 9 and 10, a Km for E2 of 14.2 x 10(-6)M, a Vmax of 0.9 x 10(-6)M x min-1 in Tris-HCl buffer 50 mM pH 9.	Tris hydrochloride	132-140	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
526385-7	1979	The average maintenance dose of ketamine was 41 +/- 21 microgram kg-1 min-1, but there was an obvious decrease in the dose required as anaesthesia progressed.	Ketamine	32-40	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
82838-3	1978	Steroid therapy modified SACE activity; 60 sarcoidosis patients who were not being treated with steroids had significantly higher enzyme activities (58 +/- 24 nmol min-1 ml-1) than 30 steroid-treated sarcoidosis patients (40 +/- 19 nmol min-1 ml-1).	Steroids	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	164-174
82838-3	1978	Steroid therapy modified SACE activity; 60 sarcoidosis patients who were not being treated with steroids had significantly higher enzyme activities (58 +/- 24 nmol min-1 ml-1) than 30 steroid-treated sarcoidosis patients (40 +/- 19 nmol min-1 ml-1).	Steroids	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	237-247
154917-2	1978	At preset oxygen flow rates of less than 1 litre min-1 unacceptable errors were found.	Oxygen	10-16	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
718782-4	1978	Maximum plasma concentration of morphine (CP max) was 75.3 +/- 6.0 (mean elimination rate constant (k) 4.85 X 10(-3) min-1 and half-life (T1/2) = 143 min for the preanaesthetic group.	Morphine	32-40	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
282106-4	1978	The metabolic clearance rate of plasma noradrenaline in normal subjects was approximately 1 1 min-1 m-2, whereas in essential hypertensive patients it was significantly reduced to approximately 0.6 1 min-1 m-2.	Norepinephrine	39-52	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
282106-4	1978	The metabolic clearance rate of plasma noradrenaline in normal subjects was approximately 1 1 min-1 m-2, whereas in essential hypertensive patients it was significantly reduced to approximately 0.6 1 min-1 m-2.	Norepinephrine	39-52	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
229150-3	1978	= 45; 34.1 +/- 3.2 (m +/- SE), 378 +/- 43, 298 +/- 48 pmol cAMP x min-1 x mg membrane protein-1), the same stimulability of AC by TSH (11.3 +/- 1.4--fold over basal level) and by NaF (8.1 +/- 1.8-fold), the same apparent TSH binding equilibrium constants (5.6 +/- 0.7 and 406 +/- 57 nM) and the same TSH binding site concentrations (2.2 +/- 0.4, 27.8 +/- 5.9 pmol x mg membrane protein-1).	Cyclic AMP	59-63	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
696180-6	1978	Creatinine clearance during the first 3 days of life increased from 5.3 to 21.9 ml/min/1.73 m2.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
687501-2	1978	2 Clonidine disposition could be described by a two compartment open model and pharmacokinetic parameters show a rapid distribution phase of 20--30 min and a mean plasma clearance of 4.6 ml min-1 kg-1 (75--200 microgram).	Clonidine	2-11	CD59 molecule (CD59 blood group)	Homo sapiens	190-200
722557-10	1978	The rate constants were in 0.2 mM-phosphate 1.29 X 10(-3) min-1, in 0.2 mM 1.95 X 10(-3) min-1, and in 2 mM 3.21 X 10(-3) min-1 at 37 degrees C. After changing the external solution the efflux reached a new level with a time constant of about 9 min.	Phosphates	34-43	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
722557-24	1978	The efflux of 22Na had a rate constant of 0.050 min-1 in Locke and 0.046 min-1 in Tris-Locke.	Tromethamine	82-86	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
25675-4	1978	The rate constant was calculated to be 1.05 X 10(-2) min-1 at pH 4.0 (50 degrees C), corresponding to a catalysis of the hydrolysis of ATP by a factor of 150.	Adenosine Triphosphate	135-138	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
670016-4	1978	The oxygen consumption (51.6 and 59.7 ml.min-1.kg-1 BW) for 55-kg load (at 4.09 and 4.64 km.h-1) possibly reached maximal aerobic capacity.	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
658106-4	1978	This finding was explained by a very rapid increase in renal digoxin clearance in the first 3 months--32 +/- 7 ml/min/1.73m2 at 1 week to 65.6 +/- 30 at 3 months.	Digoxin	61-68	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
658106-5	1978	The subsequent increase in digoxin clearance was much slower, e. g. to 87.7 +/- 43 ml/min/1.73m2 at 12 months.	Digoxin	27-34	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
649837-2	1978	The dosage of dobutamine started from 2.5 mcg kg-1 min-1 and was increased stepwise to 5, 7.5, 10, 12.5 and 15 mcg kg-1 min-1.	Dobutamine	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
649837-2	1978	The dosage of dobutamine started from 2.5 mcg kg-1 min-1 and was increased stepwise to 5, 7.5, 10, 12.5 and 15 mcg kg-1 min-1.	Dobutamine	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
649837-13	1978	We conclude that in patients with depressed cardiac function dobutamine at low doses of 2.5 mcg kg-1 min-1 decreases afterload and filling pressures.	Dobutamine	61-71	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
653312-2	1978	infusions of isoprenaline in a dose of 0.03 microgram x kg-1 x min-1 over a period of 6 min.	Isoproterenol	13-25	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
204349-5	1978	Viozt = 28.3 micron.min-1 at 30 degrees C. Equilibrium exchange entry of cyclic AMP has similar kinetics to zero trans influx, though the system does show counterflow.	Cyclic AMP	73-83	CD59 molecule (CD59 blood group)	Homo sapiens	20-25
25420-5	1978	The rate constants of the intermediate formation and its dehydration were found to be 38x10(-4) and 47x10(-4) /min-1/ for adenosine, and 33x10(-4) and 10x10(-4) /min-1/ for cytidine.	Adenosine	122-131	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
25420-5	1978	The rate constants of the intermediate formation and its dehydration were found to be 38x10(-4) and 47x10(-4) /min-1/ for adenosine, and 33x10(-4) and 10x10(-4) /min-1/ for cytidine.	Cytidine	173-181	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
620020-6	1978	Under equilibrium-exchange conditions the galactose transport is mediated apparently by a single site with K = 146 mM and V = 521 mM.min-1.	Galactose	42-51	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
35061-3	1978	Doses of dobutamine of 5 or 7.5 microgram.kg-1.min-1 corrected the IC, PCP and TPR.	Dobutamine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
35061-4	1978	Dobutamine ameliorated the SI and SWILV in an increasing fashion up to a dose of 10 microgram.kg-1.min-1 only and without restoring them to the control values of the pre-operative period.	Dobutamine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
35061-7	1978	Tests of vascular filling (pre-charge tests) carried out in the second group of patients under 10 microgram,kg-1.min-1 of dobutamine and in a third group under 15 microgram.kg-1.min-1 showed a good cardiac adaptation to filling, equal or superior to that of the pre-operative period.	Dobutamine	122-132	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
35061-8	1978	It also appeared that the amelioration of CF obtained with a moderate vascular filling (300 ml of low molecular weight dextran) under 10 microgram.kg-1.min-1 of dobutamine is greatly superior to the amelioration obtained by 10 to 15 microgram.kg-1.min-1 of dobutamine.	Dextrans	119-126	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
35061-8	1978	It also appeared that the amelioration of CF obtained with a moderate vascular filling (300 ml of low molecular weight dextran) under 10 microgram.kg-1.min-1 of dobutamine is greatly superior to the amelioration obtained by 10 to 15 microgram.kg-1.min-1 of dobutamine.	Dobutamine	161-171	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
637662-7	1978	When the clearance was less than 10 ml/min/1.73 m2, the urinary creatinine excretion for children under the age of 2 was 58% of the normal for the age and for children over 2, it was 86% of the expected mean.	Creatinine	64-74	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
580191-3	1978	The constants characterising this inhibition, the bimolecular rate ka (51.8 M-1 min-1 for epinephrine and 15.9 M-1 min-1 for norepinephrine) and the enzyme inhibitor dissociation constant (8.52 mM for epinephrine and 12.2 mM norepinephrine) were determined.	Epinephrine	90-101	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
741096-5	1978	DOPA and isoprenaline increased cardiac index by an average of 1.01 and 0.94 1 min--1 m--2; noradrenaline did not significantly improve peripheral perfusion.	Dopamine	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	79-85
741096-5	1978	DOPA and isoprenaline increased cardiac index by an average of 1.01 and 0.94 1 min--1 m--2; noradrenaline did not significantly improve peripheral perfusion.	Isoproterenol	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	79-85
741096-8	1978	DOPA increased coronary blood flow and myocardial O2 consumption by an average of 28 and 3.60 ml min--1 100 g--1, noradrenaline by 16 and 1.93 and isoprenaline by 62 and 4.25 ml min--1 100 g--1 respectively.	Dopamine	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	97-103
741096-8	1978	DOPA increased coronary blood flow and myocardial O2 consumption by an average of 28 and 3.60 ml min--1 100 g--1, noradrenaline by 16 and 1.93 and isoprenaline by 62 and 4.25 ml min--1 100 g--1 respectively.	Dopamine	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	178-184
233639-3	1978	Steroid therapy modified SACE activity; 60 sarcoidosis patients who were not being treated with steroids had significantly higher enzyme activities (58 +/- 24 nmol min-1 ml-1) than 30 steroid-treated sarcoidosis patients (40 +/- 19 nmol min-1 ml-1).	Steroids	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	164-174
233639-3	1978	Steroid therapy modified SACE activity; 60 sarcoidosis patients who were not being treated with steroids had significantly higher enzyme activities (58 +/- 24 nmol min-1 ml-1) than 30 steroid-treated sarcoidosis patients (40 +/- 19 nmol min-1 ml-1).	Steroids	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	237-247
676298-2	1978	With the progressive cycling loading on a veloergometer up to an oxygen uptake of 1.5 1/min--1, considerably higher oxygen uptake was established in the obese as comparable loading grades and in some of the cases--hypeptensive reaction was found.	Oxygen	65-71	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
676298-2	1978	With the progressive cycling loading on a veloergometer up to an oxygen uptake of 1.5 1/min--1, considerably higher oxygen uptake was established in the obese as comparable loading grades and in some of the cases--hypeptensive reaction was found.	Oxygen	116-122	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
336168-3	1977	A patient is described who had a baseline creatinine clearance of about 35 mL/min-1.73 m2 and two successful pregnancies.	Creatinine	42-52	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
144133-8	1977	Within experimental limits, the net flux of reaction in each partial step was compatible with the (Na+,K+)-stimulated hydrolysis of ATP (about 324 and 300 nmol-mg-1-min-1, respectively).	Adenosine Triphosphate	132-135	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
590309-4	1977	The ultimate serum half-life was 1.1 h. Excretion of cefuroxime in the urine was almost complete in 24 h, the clearance being 150 ml/min/1.73m2.	Cefuroxime	53-63	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
411658-7	1977	The enzyme has a pH optimum of 4.5 +/- 0.3 and KM and V values of 0.14-0.74 mM, and 1.04-3.68 mumol mg-1 min-1 for three aryl 2-acetamido-2-deoxy-alpha-D-glucosides and UDP-N-acetylglucosamine.	aryl 2-acetamido-2-deoxy-alpha-d-glucosides	121-164	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
411658-7	1977	The enzyme has a pH optimum of 4.5 +/- 0.3 and KM and V values of 0.14-0.74 mM, and 1.04-3.68 mumol mg-1 min-1 for three aryl 2-acetamido-2-deoxy-alpha-D-glucosides and UDP-N-acetylglucosamine.	Uridine Diphosphate N-Acetylglucosamine	169-192	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
579513-5	1977	Namely, at 4.5 x 10(-6)M, 9 x 10(-6)M, 1.8 x 10(-5)M and 3.6 x 10(-5)M heparin concentrations, the rate constants were 0.27 min -1, 0.17 min-1, 0.11 min-1 and 0.06 min-1, respectively.	Heparin	71-78	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
579513-5	1977	Namely, at 4.5 x 10(-6)M, 9 x 10(-6)M, 1.8 x 10(-5)M and 3.6 x 10(-5)M heparin concentrations, the rate constants were 0.27 min -1, 0.17 min-1, 0.11 min-1 and 0.06 min-1, respectively.	Heparin	71-78	CD59 molecule (CD59 blood group)	Homo sapiens	149-154
579513-5	1977	Namely, at 4.5 x 10(-6)M, 9 x 10(-6)M, 1.8 x 10(-5)M and 3.6 x 10(-5)M heparin concentrations, the rate constants were 0.27 min -1, 0.17 min-1, 0.11 min-1 and 0.06 min-1, respectively.	Heparin	71-78	CD59 molecule (CD59 blood group)	Homo sapiens	149-154
911781-11	1977	Sonolysis of a dilute aqueous solution of uracil yielded pseudo-first-order kinetics in terms of [Ura] with a rate constant of 3.9 X 10(-2) min-1, implying that the rate-limiting step is the reaction of HO- with the base.	Uracil	42-48	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
911781-11	1977	Sonolysis of a dilute aqueous solution of uracil yielded pseudo-first-order kinetics in terms of [Ura] with a rate constant of 3.9 X 10(-2) min-1, implying that the rate-limiting step is the reaction of HO- with the base.	Uracil	98-101	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
908472-1	1977	The effect of peripheral and intraportal infusions on 0.86 pmol/kg-min-1 of glucagon on plasma glucose, plasma insulin, and glucose tolerance was examined in four normal subjects.	Glucagon	76-84	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
580100-10	1977	4. tit was concluded that PGF 2 alpha could be administered most effectively by intravvenous drip infusion at 0.5 microgram/kg/min 3 times daily for 3 days after surgery for the satisfactory recovery from the postoperative ileus, and no appreciable side effect was observed.	Prostaglandins F	26-29	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
902650-8	1977	Oxygen uptake (ml - kg-1) and heart rate (beats - min-1) increase more in running than in walking, actual steprate (steps - min-1) however increases less in running compared to walking.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
196859-2	1977	Infusion of glucagon (75 ng min-1 kg-1) for 2 h into normal subjects resulted in an initial increase in plasma cyclic AMP concentration, then a decline despite continuation of the hormone infusion and maintenance of high concentrations of circulating immunoreactive glucagon.	Glucagon	12-20	CD59 molecule (CD59 blood group)	Homo sapiens	28-38
196859-2	1977	Infusion of glucagon (75 ng min-1 kg-1) for 2 h into normal subjects resulted in an initial increase in plasma cyclic AMP concentration, then a decline despite continuation of the hormone infusion and maintenance of high concentrations of circulating immunoreactive glucagon.	Cyclic AMP	111-121	CD59 molecule (CD59 blood group)	Homo sapiens	28-38
196859-2	1977	Infusion of glucagon (75 ng min-1 kg-1) for 2 h into normal subjects resulted in an initial increase in plasma cyclic AMP concentration, then a decline despite continuation of the hormone infusion and maintenance of high concentrations of circulating immunoreactive glucagon.	Glucagon	266-274	CD59 molecule (CD59 blood group)	Homo sapiens	28-38
847290-2	1977	The renal clearances of digoxin were low at one month of age (50 ml/min/1.73 m2) but increased progressively until the adult range was attained at about five months of age (130-150 ml/min/1.73 m2).	Digoxin	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
558160-6	1977	After an infusion of 0,3 g.kg-1.min-1 glycerol disappears from the blood with an elimination constant of 0,024 min-1 and a half life of 28,9 minutes.	Glycerol	38-46	CD59 molecule (CD59 blood group)	Homo sapiens	32-37
558160-6	1977	After an infusion of 0,3 g.kg-1.min-1 glycerol disappears from the blood with an elimination constant of 0,024 min-1 and a half life of 28,9 minutes.	Glycerol	38-46	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
847290-2	1977	The renal clearances of digoxin were low at one month of age (50 ml/min/1.73 m2) but increased progressively until the adult range was attained at about five months of age (130-150 ml/min/1.73 m2).	Digoxin	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
605767-2	1977	Seven received bupivacaine and eight etidocaine in a dose rate of 2 mg.min-1 over a period of 150 min.	Etidocaine	37-47	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
605767-6	1977	After 150 min infusion, the splanchnic clearance of bupivacaine and etidocaine was 0.76 +/- 0.27 and 1.32 +/- 0.21 1.min-1, respectively.	Bupivacaine	52-63	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
605767-6	1977	After 150 min infusion, the splanchnic clearance of bupivacaine and etidocaine was 0.76 +/- 0.27 and 1.32 +/- 0.21 1.min-1, respectively.	Etidocaine	68-78	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
96642-7	1977	min-1 during the first weeks of life with 0.25 g.kg-1.h-1 glycerol irrespective of gestational age and intra-uterine growth retardation; and it rose to 31.8 ml.kg-1.min-1 in older infants.	Glycerol	58-66	CD59 molecule (CD59 blood group)	Homo sapiens	0-5
990259-3	1976	Luciferase has been found to be inactivated by ethoxyformic anhydride with a second-order rate constant of 146 M-1 min-1 at pH 6.1 and 0 degrees C with a concomitant increase in absorbance at 240 nm due to formation of ethoxyformylhistidyl derivatives.	ethoxyformylhistidyl	219-239	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
8458-3	1976	Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1).	Aminooxyacetic Acid	0-15	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
8458-3	1976	Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1).	Aminooxyacetic Acid	0-15	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
8458-3	1976	Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1).	Aminooxyacetic Acid	0-15	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
8458-3	1976	Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1).	Schiff Bases	28-39	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
8458-3	1976	Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1).	Schiff Bases	28-39	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
8458-3	1976	Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1).	Schiff Bases	28-39	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
8458-3	1976	Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1).	Carbon	159-165	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
8458-3	1976	Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1).	Carbon	159-165	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
8458-3	1976	Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1).	p-pyridoxal	174-185	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
8458-3	1976	Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1).	p-pyridoxal	174-185	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
782811-6	1976	The renal clearance of amikacin was determined during a 4 hr constant infusion in 3 test individuals; the average clearance was 84.3 ml/min - 1.73 m2.	Amikacin	23-31	CD59 molecule (CD59 blood group)	Homo sapiens	136-143
969022-3	1976	Maximal oxygen uptake (VO2 max) during HOI was 3.18 liters - min-1, which was not statistically different from the mean of 3.29 liters- min-1 in air.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
986609-3	1976	The oxygen uptake increased from 0.261 - min-1 at rest to about 1.61-min-1 during work.	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
986609-3	1976	The oxygen uptake increased from 0.261 - min-1 at rest to about 1.61-min-1 during work.	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
931929-2	1976	Measurements were made with the subjects at rest, exercising at approximately 0.8 liter oxygen-min-1, and very vigorously at 1.8-2.0 liters oxygen-min-1.	Oxygen	88-94	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
931929-2	1976	Measurements were made with the subjects at rest, exercising at approximately 0.8 liter oxygen-min-1, and very vigorously at 1.8-2.0 liters oxygen-min-1.	Oxygen	140-146	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
1276184-8	1976	An inhibition between Z, the physiological donor and the oxidized reaction center pigment P+ occurs, proceeding as exp (-kiti)where ti is the incubation time with hydroxylamine and ki=(alpha[NH2OH]) min-1, with [NH2OH] in mM and alpha=0.14 mM-1.	Hydroxylamine	163-176	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
1276184-8	1976	An inhibition between Z, the physiological donor and the oxidized reaction center pigment P+ occurs, proceeding as exp (-kiti)where ti is the incubation time with hydroxylamine and ki=(alpha[NH2OH]) min-1, with [NH2OH] in mM and alpha=0.14 mM-1.	Hydroxylamine	191-196	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
1277710-4	1976	The body clearance of theophylline was appreciably larger and relatively more variable in smokers (100 +/-44 ml/min/1.73 m2) than in nonsmokers (45 +/-13 ml/min/1.73 m2).	Theophylline	22-34	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
1277710-4	1976	The body clearance of theophylline was appreciably larger and relatively more variable in smokers (100 +/-44 ml/min/1.73 m2) than in nonsmokers (45 +/-13 ml/min/1.73 m2).	Theophylline	22-34	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
1262168-4	1976	X 10(-2) min.-1 for kfa and 3.51 +/- 0.81 X 10(-3) min.-1 for kdpa in the involved eye, and 0.91 +/- 0.12 X 10(-2) min.-1 for kfa and 1.36 +/- 0.39 X 10(-3) min.-1 for kdpa in the fellow eye.	CHEMBL4090167	20-23	CD59 molecule (CD59 blood group)	Homo sapiens	9-15
1262168-6	1976	In six patients, the coefficients were measured during the remission, giving average values of 0.81 +/- 0.08 X 10(-2) min.-1 for kfa and 1.36 +/- 0.16 X 10(-3) min.-1 for kdpa in the involved eye, and 0.78 +/- 0.07 X 10(-2) min.-1 for kfa and 1.20 +/- 0.10 X 10(-3) min.-1 for kdpa in the fellow eye.	CHEMBL4090167	129-132	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
941187-3	1976	Human endometrial and myometrial tissue pieces were incubated with radioactively labeled progesterone in nutrient medium for 20 min., 1 hr and 2 hrs.	Progesterone	89-101	CD59 molecule (CD59 blood group)	Homo sapiens	128-144
1025322-6	1976	The most rational method proved to consist in repeated injections of 5ml of 10% CaCl2 solution every 30 min--1 hour which resulted in a moderate elevation of the blood content of the total and dialysing calcium.	Calcium Chloride	80-85	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
1253786-6	1976	), in 2 subjects exercising on a bicycle ergometer, DO2 was found to increase from a resting value of about 32 ml- min-1 - Torr-1 to 107 ml - min-1 - Torr-1 for an eightfold increase of O2 uptake.	do2	52-55	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
1253786-6	1976	), in 2 subjects exercising on a bicycle ergometer, DO2 was found to increase from a resting value of about 32 ml- min-1 - Torr-1 to 107 ml - min-1 - Torr-1 for an eightfold increase of O2 uptake.	do2	52-55	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
1253786-6	1976	), in 2 subjects exercising on a bicycle ergometer, DO2 was found to increase from a resting value of about 32 ml- min-1 - Torr-1 to 107 ml - min-1 - Torr-1 for an eightfold increase of O2 uptake.	Oxygen	53-55	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
1253786-6	1976	), in 2 subjects exercising on a bicycle ergometer, DO2 was found to increase from a resting value of about 32 ml- min-1 - Torr-1 to 107 ml - min-1 - Torr-1 for an eightfold increase of O2 uptake.	Oxygen	53-55	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
935837-2	1976	Oxygen consumption of  normal subjects when walking at velocities of 0.5, 1.0 and 1.5 m sec-1 was 8.0, 9.8 and 13.6 ml kg-1 min-1 respectively.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
935837-3	1976	For subjects walking on crutches with the leg encased in a Plaster of Paris cast, the oxygen consumption at these velocities was 12.0, 17.5 and 25.3 ml kg-1 min-1 respectively.	Oxygen	86-92	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
1194146-6	1975	The subjects attained a work rate of 1,728.2 +/- 223 kpm-min-1 on a continuous progressive bicycle ergometer test and had mean maximal ventilations of 152.5 +/- 27.7 1-min-1 BTPS.	btps	174-178	CD59 molecule (CD59 blood group)	Homo sapiens	168-173
1159264-6	1975	By extrapolation of these heart-rate determinations to "maximal heart rate," the maximal oxygen uptake was estimated and expressed as L times min-1 and as ml x min-1 and as ml times kg-1 x min-1.	Oxygen	89-95	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
1159264-6	1975	By extrapolation of these heart-rate determinations to "maximal heart rate," the maximal oxygen uptake was estimated and expressed as L times min-1 and as ml x min-1 and as ml times kg-1 x min-1.	Oxygen	89-95	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
1159264-6	1975	By extrapolation of these heart-rate determinations to "maximal heart rate," the maximal oxygen uptake was estimated and expressed as L times min-1 and as ml x min-1 and as ml times kg-1 x min-1.	Oxygen	89-95	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
1163670-4	1975	At 37 degrees C, the value of bladder tissue O2 consumption was 4.4 times 10(-3) min-1 and the value of the Krogh constant for O2 was 2.22 times 10(-5)cm2min-1atm-1.	Oxygen	45-47	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
1179325-5	1975	The cardiac frequencies at oxygen uptake of 0-75 and 1-01 min-1 were significantly higher in the patient groups than in the normal men, and were highest in patient group S. The cardiac output when related to the oxygen uptake was in the normal range in all three groups of subjects, so that the patients had smaller stroke volumes than the normal men.	Oxygen	27-33	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
1179325-6	1975	Ventilation at oxygen uptakes of 0-75 and 1-01 min-1 was significantly higher in both patient groups than in the normal subjects; there were no significant differences between the two patient groups, Values for dead space/tidal volume ration, alveolar-arterial oxygen gradient, and the percent venous admixture measured during a constant work rate test were significantly greater than normal in the patient groups.	Oxygen	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
1122319-3	1975	At pH 7.0, 25 DEGREES C, dimethylsuberimidate is hydrolyzed with an apparent first order rate constant of 0.016 min-1, to give dimethylsuberate as the principal product.	Dimethyl Suberimidate	25-45	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
808630-2	1975	The resealing process is first-order at temperatures above 20-25 degrees C in isotonic salt, with rate constants ranging from 0.01-0.15 min-1.	Salts	87-91	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
1166770-4	1975	The calculated values of rate constant of transmembranal sodium fluxes are 0.0282+/-0.0052 min-1 and the half-time of the exchange of sodium between intracellular compartments is 24.27+/-4.53 min.	Sodium	57-63	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
240693-3	1975	The specific activity of the pure enzyme (63 mumol of urocanic acid min-1 mg-1) is similar to those so far reported for the enzyme from other sources.	Urocanic Acid	54-67	CD59 molecule (CD59 blood group)	Homo sapiens	68-78
1152344-4	1975	The calculated renal clearance of beta-methyl-digoxin was 63 +/- 8.1 ml/min e. g. 57.5 +/- 8.3 ml/min/1.73 m2.	Medigoxin	34-53	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
1122319-3	1975	At pH 7.0, 25 DEGREES C, dimethylsuberimidate is hydrolyzed with an apparent first order rate constant of 0.016 min-1, to give dimethylsuberate as the principal product.	phorone	127-143	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
1112779-4	1975	This complex is then reversibly converted to a different Complex II in a slow first order reaction (k2 equals 40 min--1; k-2 equals 0.07 min--1), which is accompanied by major spectral perturbations of the flavin spectrum.	4,6-dinitro-o-cresol	206-212	CD59 molecule (CD59 blood group)	Homo sapiens	113-119
1139445-3	1975	While holding-still, metabolic heat production (Hm,kcal-min--1) was inversely related to water temperature (Tw, degrees C) according to the equation Hm equals 4.19 minus-0.117 Tw.	Water	89-94	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
1112779-4	1975	This complex is then reversibly converted to a different Complex II in a slow first order reaction (k2 equals 40 min--1; k-2 equals 0.07 min--1), which is accompanied by major spectral perturbations of the flavin spectrum.	4,6-dinitro-o-cresol	206-212	CD59 molecule (CD59 blood group)	Homo sapiens	137-143
1179157-4	1975	In spite of that the secretion rate of bile acids was low (less than or equal to 7.5 mumol x min-1).	Bile Acids and Salts	39-49	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
1140624-2	1975	Ileal flow was increased by PGF2 alpha (six subjects) from a mean of 1-69 ml min-1 to 4-63 ml min-1 (P smaller than 0-01); it also increased in the two subjects given PGE2.	Dinoprost	28-32	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
1140624-2	1975	Ileal flow was increased by PGF2 alpha (six subjects) from a mean of 1-69 ml min-1 to 4-63 ml min-1 (P smaller than 0-01); it also increased in the two subjects given PGE2.	Dinoprost	28-32	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
1162297-2	1975	Oxygen intake at a given submaximal work level of 450 kmp min-1 and cardiac frequency at an oxygen intake of 1.5 I min-1 were significantly higher (p less than 0.001) in the injured compared with the uninjured limbs of the patients and normal subjects.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
1162297-2	1975	Oxygen intake at a given submaximal work level of 450 kmp min-1 and cardiac frequency at an oxygen intake of 1.5 I min-1 were significantly higher (p less than 0.001) in the injured compared with the uninjured limbs of the patients and normal subjects.	Oxygen	92-98	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
34009435-14	2021	Compared with the no-exercise group, peak oxygen uptake improved after both morning (estimated effect 1.3 ml min-1 kg-1 [95% CI 0.5, 2.0], p = 0.003) and evening exercise (estimated effect 1.4 ml min-1 kg-1 [95% CI 0.6, 2.2], p = 0.001).	Oxygen	42-48	CD59 molecule (CD59 blood group)	Homo sapiens	109-119
4339388-5	1972	Intravertebral clonidine also greatly reduced the reflex response to carotid occlusion and the effects of an intravertebral infusion of angiotensin (1 ng/kg)/min.3.	Clonidine	15-24	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
19867069-12	1906	The saline solution of the antilysin, which for convenience has been denominated "protectin," behaves in all respects like the native antilytic sera except that it is uninfluenced by temperatures of 90 degrees C. or even higher temperatures.	Sodium Chloride	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	82-91
31216951-7	2021	The time with an oxygen uptake above 35 ml kg-1 min-1 was longer in the new test, 6.4 vs 4.7 min.	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
33243574-8	2021	The rate constants obtained for the degradation of MB by C-TiO2 and C-BiPO4 at 20  C were 9.739 x 10-7 mM min-1 and 1.111 x 10-7 mM min-1, respectively.	Carbon	57-58	CD59 molecule (CD59 blood group)	Homo sapiens	106-117
33351148-11	2021	IH increased binding of intracellular CD59 to syntaxin-3, which dissociated syntaxin-3 from voltage-sensitive calcium channel Cav1.2, and activated WPB exocytosis in a calcium-dependent manner.	Calcium	110-117	CD59 molecule (CD59 blood group)	Homo sapiens	38-42
33351148-11	2021	IH increased binding of intracellular CD59 to syntaxin-3, which dissociated syntaxin-3 from voltage-sensitive calcium channel Cav1.2, and activated WPB exocytosis in a calcium-dependent manner.	Calcium	168-175	CD59 molecule (CD59 blood group)	Homo sapiens	38-42
33556395-6	2021	Based on the same amount of immobilized enzyme (0.2 mg), the specific activities of hydrolysis of p-nitrophenyl butyrate substrate at room temperature of in situ immobilized carboxyl esterase (CE) and crosslinked CE were 11.37 and 7.63 mM min-1 mg-1, respectively (100 mM phosphate buffer, pH 8.0).	4-nitrophenyl butyrate	98-120	CD59 molecule (CD59 blood group)	Homo sapiens	239-249
33243574-8	2021	The rate constants obtained for the degradation of MB by C-TiO2 and C-BiPO4 at 20  C were 9.739 x 10-7 mM min-1 and 1.111 x 10-7 mM min-1, respectively.	titanium dioxide	59-63	CD59 molecule (CD59 blood group)	Homo sapiens	106-117
33243574-8	2021	The rate constants obtained for the degradation of MB by C-TiO2 and C-BiPO4 at 20  C were 9.739 x 10-7 mM min-1 and 1.111 x 10-7 mM min-1, respectively.	c-bipo4	68-75	CD59 molecule (CD59 blood group)	Homo sapiens	106-117
31469339-5	2021	The degrading rate constant of glyphosate degradation was calculated to be kapp = 0.063 min-1.	glyphosate	31-41	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
33243515-4	2021	The activities of polyphosphate kinase (PPK) and exopolyphosphatase (PPX) tightly associated with phosphorus biological removal ranged from 0.356 to 11.844 mumol hydroxamic acid min-1 mg-1 protein, and 0.008 to 0.446 mumol p-nitrophenol min-1 mg-1 protein, respectively.	Phosphorus	98-108	CD59 molecule (CD59 blood group)	Homo sapiens	178-188
33243515-4	2021	The activities of polyphosphate kinase (PPK) and exopolyphosphatase (PPX) tightly associated with phosphorus biological removal ranged from 0.356 to 11.844 mumol hydroxamic acid min-1 mg-1 protein, and 0.008 to 0.446 mumol p-nitrophenol min-1 mg-1 protein, respectively.	Phosphorus	98-108	CD59 molecule (CD59 blood group)	Homo sapiens	237-247
33297175-10	2021	An aeration rate >0.3 L min-1 kg-1 DOM reduces the kCOD likely due to excess water evaporation and ventilation cooling.	Water	77-82	CD59 molecule (CD59 blood group)	Homo sapiens	24-34
33219433-6	2021	RESULTS: Maximal oxygen uptake was impaired in individuals with type 1 diabetes compared with in healthy participants (35.6 +- 7.7 vs 39.6 +- 6.8 ml min-1 kg-1, p < 0.01) despite comparable levels of habitual physical activity (moderate to vigorous physical activity by accelerometery, 234.9 +- 160.0 vs 280.1 +- 114.9 min/week).	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	149-159
31318310-7	2021	The pseudo-first-order rate constant was estimated as 1.648 x 10 -2 min-1 for the reduction of 4-NP using g-C3N4/Bi2S3 composite in 1 h reaction time.	4-nonylphenol	95-99	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
33151456-4	2020	The retention of 4-chlorophenol (4-C) and 2,4,6-trichlorophenol (TCP) by the TBP-treated iron(III)-immobilized PUF fitted well with the pseudo-second-order kinetic model with a rate constant (k) of 0.04 and 0.15 g (mg min)-1, respectively.	4-chlorophenol	17-31	CD59 molecule (CD59 blood group)	Homo sapiens	218-224
33151456-4	2020	The retention of 4-chlorophenol (4-C) and 2,4,6-trichlorophenol (TCP) by the TBP-treated iron(III)-immobilized PUF fitted well with the pseudo-second-order kinetic model with a rate constant (k) of 0.04 and 0.15 g (mg min)-1, respectively.	ferric sulfate	89-98	CD59 molecule (CD59 blood group)	Homo sapiens	218-224
32191294-7	2020	Lower magnesium levels were associated with greater incidence of PAD, particularly in those with estimated glomerular filtration rate (eGFR) >=60 mL/min/1.73 m2 (n = 11 606).	Magnesium	6-15	CD59 molecule (CD59 blood group)	Homo sapiens	149-154
31683056-9	2020	In the longitudinal analysis, exposure to 5-ASAs or methotrexate was not associated with change in eGFR, whereas azathioprine was associated with a slightly higher eGFR (0.32 mL/min/1.73 m2; 95% CI, 0.16-0.48).	Azathioprine	113-125	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
33091682-11	2020	Increased plasma CD59 concentrations correlated with decreased platelet count and increased lactate dehydrogenase, creatinine, aspartate transaminase, urine protein/creatinine ratio, systolic blood pressure and diastolic blood pressure (P < 0.01, all correlations).	Creatinine	115-125	CD59 molecule (CD59 blood group)	Homo sapiens	17-21
33091682-11	2020	Increased plasma CD59 concentrations correlated with decreased platelet count and increased lactate dehydrogenase, creatinine, aspartate transaminase, urine protein/creatinine ratio, systolic blood pressure and diastolic blood pressure (P < 0.01, all correlations).	Creatinine	165-175	CD59 molecule (CD59 blood group)	Homo sapiens	17-21
32824874-5	2020	Of several variables tested, the estimated glomerular filtration rate (eGFR) was statistically significantly (inversely) associated with lithium levels, mainly in individuals with slightly impaired renal function (eGFR < 75 mL/min/1.73 m2).	Lithium	137-144	CD59 molecule (CD59 blood group)	Homo sapiens	227-232
32130637-5	2020	The maximum CO2 uptake rate of 182 mg L-1 day-1 was achieved for formulated flue gas flow rate above 100 mL min-1.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	12-15	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
32806656-4	2020	The oxygen permeation fluxes across a Ce0.9Pr0.1O2-delta-Nd0.5Sr0.5Fe0.9Cu0.1O3-delta membrane reached up to 1.02 mL min-1 cm-2 and 0.63 mL min-1 cm-2 under an air/He and air/CO2 gradient at T = 1223 K, respectively.	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	117-127
32806656-4	2020	The oxygen permeation fluxes across a Ce0.9Pr0.1O2-delta-Nd0.5Sr0.5Fe0.9Cu0.1O3-delta membrane reached up to 1.02 mL min-1 cm-2 and 0.63 mL min-1 cm-2 under an air/He and air/CO2 gradient at T = 1223 K, respectively.	Oxygen	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	140-150
32806656-4	2020	The oxygen permeation fluxes across a Ce0.9Pr0.1O2-delta-Nd0.5Sr0.5Fe0.9Cu0.1O3-delta membrane reached up to 1.02 mL min-1 cm-2 and 0.63 mL min-1 cm-2 under an air/He and air/CO2 gradient at T = 1223 K, respectively.	Helium	164-166	CD59 molecule (CD59 blood group)	Homo sapiens	117-127
32806656-4	2020	The oxygen permeation fluxes across a Ce0.9Pr0.1O2-delta-Nd0.5Sr0.5Fe0.9Cu0.1O3-delta membrane reached up to 1.02 mL min-1 cm-2 and 0.63 mL min-1 cm-2 under an air/He and air/CO2 gradient at T = 1223 K, respectively.	Carbon Dioxide	175-178	CD59 molecule (CD59 blood group)	Homo sapiens	117-127
32130637-5	2020	The maximum CO2 uptake rate of 182 mg L-1 day-1 was achieved for formulated flue gas flow rate above 100 mL min-1.	flue	76-80	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
32234625-7	2020	Results showed that carbonate ions end product distribution had a highest carbonate granulation efficiency at [Carbonate]G of 95-96% using S of 10.6 and QT of 60 mL min-1.	Carbonates	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
32247922-9	2020	The degradation of Nap in the aqueous solution was probably initiated by photoionization, and the reaction rate constant (between 1.44 x 10-4 min-1 and 8.55 x 10-4 min-1) was much lower than that of Nap with hydroxyl radicals.	naphthalene	19-22	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
32247922-9	2020	The degradation of Nap in the aqueous solution was probably initiated by photoionization, and the reaction rate constant (between 1.44 x 10-4 min-1 and 8.55 x 10-4 min-1) was much lower than that of Nap with hydroxyl radicals.	naphthalene	19-22	CD59 molecule (CD59 blood group)	Homo sapiens	164-169
32278170-4	2020	The rates of photodegradating rhodamine B and photoreducing Cr(VI) with Bi2S3-1 can reach 93.9% in 30 min (k = 0.07675 min-1) and 95.2% in 5 min (k = 0.47351 min-1), respectively.	rhodamine B	30-41	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
32278170-4	2020	The rates of photodegradating rhodamine B and photoreducing Cr(VI) with Bi2S3-1 can reach 93.9% in 30 min (k = 0.07675 min-1) and 95.2% in 5 min (k = 0.47351 min-1), respectively.	rhodamine B	30-41	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
32278170-4	2020	The rates of photodegradating rhodamine B and photoreducing Cr(VI) with Bi2S3-1 can reach 93.9% in 30 min (k = 0.07675 min-1) and 95.2% in 5 min (k = 0.47351 min-1), respectively.	chromium hexavalent ion	60-66	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
32278170-4	2020	The rates of photodegradating rhodamine B and photoreducing Cr(VI) with Bi2S3-1 can reach 93.9% in 30 min (k = 0.07675 min-1) and 95.2% in 5 min (k = 0.47351 min-1), respectively.	chromium hexavalent ion	60-66	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
32278170-4	2020	The rates of photodegradating rhodamine B and photoreducing Cr(VI) with Bi2S3-1 can reach 93.9% in 30 min (k = 0.07675 min-1) and 95.2% in 5 min (k = 0.47351 min-1), respectively.	Bismuth sulfide (Bi2S3)	72-77	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
32278170-4	2020	The rates of photodegradating rhodamine B and photoreducing Cr(VI) with Bi2S3-1 can reach 93.9% in 30 min (k = 0.07675 min-1) and 95.2% in 5 min (k = 0.47351 min-1), respectively.	Bismuth sulfide (Bi2S3)	72-77	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
32502129-1	2020	A cross-sectional study of 358 HIV-1-infected children and adolescents living in Sub-Saharan Africa treated with tenofovir disoproxil fumarate-based regimens for a median of 1.5 interquartile range [0.6-3.1 years] showed a loss of glomerular filtration rate estimated to be 0.41 mL/min/1.73 m per month of treatment.	Tenofovir	113-142	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
32312861-7	2020	Lower peak oxygen consumption (13.5+-3.8 versus 16.6+-4.7 mL min-1 kg-1, p<0.001) was observed in the former group.	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	61-71
32251895-2	2020	According to the simulated results by COMSOL Multiphysics, the microfluidic-SERS sensor was fabricated by simultaneously introducing into 40 mmol L-1 silver nitrate solution and 0.2 mol L-1 sodium nitrate solution for about 15 min with the flow velocity at 20 mL min-1 at room temperature, respectively.	sers	76-80	CD59 molecule (CD59 blood group)	Homo sapiens	263-268
32234625-7	2020	Results showed that carbonate ions end product distribution had a highest carbonate granulation efficiency at [Carbonate]G of 95-96% using S of 10.6 and QT of 60 mL min-1.	Carbonates	74-83	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
32385603-12	2020	RESULTS: Glucose MCR/I was significantly higher during IGIVI than during oral glucose administration, independently of glycaemic status (12 +- 6 for IGIVI vs 7.4 +- 3 ml min-1 kg-1 per nmol/l for oral, p< 0.001 from paired t test).	Glucose	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	170-180
32724752-2	2020	The loss of CD55 and CD59, two GPI-anchored proteins on red blood cell surfaces, from mutations in the X-linked phosphatidylinositol glycan class A (PIGA) gene, causes unrestricted proliferation of complement activation.	Polysaccharides	133-139	CD59 molecule (CD59 blood group)	Homo sapiens	21-25
32724752-5	2020	Diagnosis of PNH relies primarily on clinical presentation and flow cytometry assays used to detect the GPI-anchored proteins, CD55 and CD59; however, fluorescein-labeled proaerolysin variant (FLAER) is seen to have a significant advantage over CD55 and CD59.	Fluorescein	151-162	CD59 molecule (CD59 blood group)	Homo sapiens	254-258
32524270-4	2020	Experimental thermal decomposition data of lumefantrine heated at 5, 10 ,15, and 20 oC min- 1 were fitted for a single-step process.	Lumefantrine	43-55	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
31522785-5	2020	l-arginine-HCl (1.2 mumol kg-1 min-1; n = 9) or l-alanine (isocaloric control: 2.4 mumol kg-1 min-1; n = 9) was continuously infused.	l-arginine-hcl	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
32045803-3	2020	By rationally controlling synthetic parameters, we find that optimum Cu0.3@Cu0.7CoOx@GO achieves a superior catalytic activity with a turnover frequency of 44.6 molH2 molM-1 min-1 in H2O and 98.2 molH2 molM-1 min-1 in 0.2 M NaOH, better than most of previously reported NM-free nanocatalysts.	Water	183-186	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
32045803-3	2020	By rationally controlling synthetic parameters, we find that optimum Cu0.3@Cu0.7CoOx@GO achieves a superior catalytic activity with a turnover frequency of 44.6 molH2 molM-1 min-1 in H2O and 98.2 molH2 molM-1 min-1 in 0.2 M NaOH, better than most of previously reported NM-free nanocatalysts.	Water	183-186	CD59 molecule (CD59 blood group)	Homo sapiens	209-214
32045803-3	2020	By rationally controlling synthetic parameters, we find that optimum Cu0.3@Cu0.7CoOx@GO achieves a superior catalytic activity with a turnover frequency of 44.6 molH2 molM-1 min-1 in H2O and 98.2 molH2 molM-1 min-1 in 0.2 M NaOH, better than most of previously reported NM-free nanocatalysts.	Sodium	224-228	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
32045803-3	2020	By rationally controlling synthetic parameters, we find that optimum Cu0.3@Cu0.7CoOx@GO achieves a superior catalytic activity with a turnover frequency of 44.6 molH2 molM-1 min-1 in H2O and 98.2 molH2 molM-1 min-1 in 0.2 M NaOH, better than most of previously reported NM-free nanocatalysts.	Sodium	224-228	CD59 molecule (CD59 blood group)	Homo sapiens	209-214
32390415-3	2020	The MIP prepared with the epitope of CD59 cell membrane glycoprotein as template allowed FZIF-8/DOX-MIPs to be enriched to tumor site by actively targeting recognization of MCF-7 cancer cells (CD59-positive).	Doxorubicin	96-99	CD59 molecule (CD59 blood group)	Homo sapiens	37-41
32390415-3	2020	The MIP prepared with the epitope of CD59 cell membrane glycoprotein as template allowed FZIF-8/DOX-MIPs to be enriched to tumor site by actively targeting recognization of MCF-7 cancer cells (CD59-positive).	Doxorubicin	96-99	CD59 molecule (CD59 blood group)	Homo sapiens	193-197
32487528-2	2020	Ertapenem neurotoxicity most classically presents as seizures in patients with end-stage renal disease (estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m2).	Ertapenem	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
32487528-3	2020	We present a patient with a baseline eGFR of 30-59 mL/min/1.73 m2 with acute kidney injury who developed non-seizure neurotoxicity after ertapenem exposure.	Ertapenem	137-146	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
32278739-10	2020	The second order rate constant for reactivation of DFP-inhibited MaBChE by 2-PAM was 1.4 M-1 min-1, but was 380 fold faster for DFP-inhibited HuBChE (kr 531 M-1 min-1).	Isoflurophate	51-54	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
32278739-10	2020	The second order rate constant for reactivation of DFP-inhibited MaBChE by 2-PAM was 1.4 M-1 min-1, but was 380 fold faster for DFP-inhibited HuBChE (kr 531 M-1 min-1).	Isoflurophate	51-54	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
32278739-10	2020	The second order rate constant for reactivation of DFP-inhibited MaBChE by 2-PAM was 1.4 M-1 min-1, but was 380 fold faster for DFP-inhibited HuBChE (kr 531 M-1 min-1).	Isoflurophate	128-131	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
32278739-12	2020	The reactivation rate of DFP-inhibited HuBChE mutant P285L by 2-PAM was reduced 5.8% (kr 92 M-1 min-1) indicating that P285 determines whether 2-PAM binds in an orientation that favors release of diisopropylphosphate.	Isoflurophate	25-28	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
32236732-7	2020	At week 6, the changes in eGFR from baseline were -2.3, -2.7 and -0.7 ml min-1 (1.73 m)-2 for the ertugliflozin 5 mg, ertugliflozin 15 mg and non-ertugliflozin groups, respectively.	ertugliflozin	98-111	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
32248414-6	2020	The model of Avrami is found to be the most appropriate model to represent the adsorption of the pollutant in any of the six modified carbons tested, the highest value of the kinetic constant being 0.055 min-1.	Carbon	134-141	CD59 molecule (CD59 blood group)	Homo sapiens	204-209
31307289-5	2020	Greater BHI was observed in OSA relative to NSA as derived from whole-brain CBF (78.6 +- 29.6 vs. 60.0 +- 20.0 mL/min2/100 g, P = 0.010) as well as from flow velocity in the superior sagittal sinus (0.48 +- 0.18 vs. 0.36 +- 0.10 cm/s2, P = 0.014).	bhi	8-11	CD59 molecule (CD59 blood group)	Homo sapiens	114-124
31147972-1	2020	PURPOSE: To compare the incidences of positive hemodynamic response (HR &gt; 100 beats min-1 or SBP &gt; 160 mmHg) during abdominal exploration and moderate pain after surgery, when using dexmedetomidine infusion and rectus sheath block.	Dexmedetomidine	188-203	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
31549922-6	2020	During Stage 1, oxygen uptake was 37.9 +- 1.5 mL kg-1 min-1 in the TRAD condition and 39.6 +- 1.8 mL kg-1 min-1 in THSL (p = 0.05).	Oxygen	16-22	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
32494740-7	2020	Intermedilysin binds to the sialyl-TF O-glycan on its erythrocyte receptor, CD59.	o-glycan	38-46	CD59 molecule (CD59 blood group)	Homo sapiens	76-80
31549922-6	2020	During Stage 1, oxygen uptake was 37.9 +- 1.5 mL kg-1 min-1 in the TRAD condition and 39.6 +- 1.8 mL kg-1 min-1 in THSL (p = 0.05).	thsl	115-119	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
31549922-7	2020	During Stage 2, VO2 was 44.6 +- 1.7 mL kg-1 min-1 in the TRAD condition and 47.0 +- 1.9 mL kg-1 min-1 in THSL (p = 0.07).	thsl	105-109	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
32148294-7	2020	Our research showed that ampicillin removal was favored at low frequency, high power (i.e., 375 kHz, 24.4 W) and continuous mode (exhibiting an initial degradation rate of 0.78 muM min-1).	Ampicillin	25-35	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
32204673-9	2021	In the optimal conditions (FH2O2 = 3.27 mmol min-1 and [Fe2+] = 0.27 mmol L-1), the photo-Fenton process achieved a percentage of organic carbon removal of 84%, in only 30 minutes of reaction, presenting an interesting potential for real industrial applications, combined, or not, with conventional technologies (as biological treatments, for example).	fh2o2	27-32	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
31991513-3	2020	During rewarming period, patients were given intravenous nitroglycerin with an infusion rate 5 and 1 microg kg-1  min-1 in high-dose and low-dose groups, respectively.	Nitroglycerin	57-70	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
32175547-9	2020	ZIF-8 prepared using terephthalic acid shows high catalytic activity with a hydrogen rate of 2333 mLH2 min-1 gcat-1 (8046 mLH2 min-1 gZn-1).	2-Methylimidazole zinc salt	0-5	CD59 molecule (CD59 blood group)	Homo sapiens	127-138
32175547-9	2020	ZIF-8 prepared using terephthalic acid shows high catalytic activity with a hydrogen rate of 2333 mLH2 min-1 gcat-1 (8046 mLH2 min-1 gZn-1).	terephthalic acid	21-38	CD59 molecule (CD59 blood group)	Homo sapiens	127-138
32175547-9	2020	ZIF-8 prepared using terephthalic acid shows high catalytic activity with a hydrogen rate of 2333 mLH2 min-1 gcat-1 (8046 mLH2 min-1 gZn-1).	Hydrogen	76-84	CD59 molecule (CD59 blood group)	Homo sapiens	127-138
31972063-7	2020	For the first time, a quantitative yield in methane is obtained at low magnetic field and mild conditions (25 mL min-1, 19 mT, 300 kHz, conversion 100%, methane selectivity 100%).	Methane	44-51	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
32101455-2	2020	1) 12 men received supraphysiological amounts of beta-alanine intravenously (0.11g kg min-1 for 150min) along with insulin infusion or without insulin infusion.	beta-Alanine	49-61	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
31870935-5	2020	Participants consumed both a carbohydrate (1.2g min-1 glucose) and a placebo beverage after breakfast consumption and omission.	Carbohydrates	29-41	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
32204673-9	2021	In the optimal conditions (FH2O2 = 3.27 mmol min-1 and [Fe2+] = 0.27 mmol L-1), the photo-Fenton process achieved a percentage of organic carbon removal of 84%, in only 30 minutes of reaction, presenting an interesting potential for real industrial applications, combined, or not, with conventional technologies (as biological treatments, for example).	Carbon	138-144	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
31812060-4	2020	In the absence of phosphate buffer, the rate constant of 2,4-DCP degradation increased from 9.4 x 10-3 to 2.4 x 10-2 min-1 when pH value was increased from 3.0 to 6.0.	Phosphates	18-27	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
31837564-6	2020	The kinetics study revealed first-order kinetics for IC color removal and the rate constant values followed the order: O2-NTP (3.0 x 10-1 min-1) > O3 (1.4 x 10-1 min-1) > N2-NTP (2.2 x 10-2 min-1) > H2O2 (negligible).	o2-ntp	119-125	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
32006326-5	2020	The rate constants for acetaldehyde production from ethanol and acetaldehyde loss averaged 3.0 +- 3.4 x 10-3 min-1 and 2.3 +- 4.5 x 10-2 min-1 respectively.	Acetaldehyde	23-35	CD59 molecule (CD59 blood group)	Homo sapiens	109-142
32006326-5	2020	The rate constants for acetaldehyde production from ethanol and acetaldehyde loss averaged 3.0 +- 3.4 x 10-3 min-1 and 2.3 +- 4.5 x 10-2 min-1 respectively.	Ethanol	52-59	CD59 molecule (CD59 blood group)	Homo sapiens	109-142
32006326-5	2020	The rate constants for acetaldehyde production from ethanol and acetaldehyde loss averaged 3.0 +- 3.4 x 10-3 min-1 and 2.3 +- 4.5 x 10-2 min-1 respectively.	Acetaldehyde	64-76	CD59 molecule (CD59 blood group)	Homo sapiens	109-142
32006326-6	2020	The branching ratio for acetaldehyde production from ethanol was 0.46 +- 0.26 and estimated acetaldehyde biological production rates ranged from 0.022 to 0.800 nM min-1.	Acetaldehyde	92-104	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
32059083-10	2020	The EVR group had significantly better kidney function (76 mL/min/1 vs. 60 mL/min/1, P < 0.001) and reduced CAV (P < 0.01) but an increased rate of early biopsy-proven treated rejections (21.2% vs 5.7%, P < 0.01) compared with the CNI group at any time point.	Everolimus	4-7	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
32059083-10	2020	The EVR group had significantly better kidney function (76 mL/min/1 vs. 60 mL/min/1, P < 0.001) and reduced CAV (P < 0.01) but an increased rate of early biopsy-proven treated rejections (21.2% vs 5.7%, P < 0.01) compared with the CNI group at any time point.	Everolimus	4-7	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
31951912-6	2020	The largest differences were observed between the p-methoxyphenyl and p-nitrophenyl-substituted Zn(II) chlorins, undergoing loss of Zn(II) with pseudo first order rate constants of 0.0789 x 10-3 and 3.70 x 10-3 min-1, respectively.	4-(2-(3-methoxyphenyl)ethyl)-1-(2-methoxyphenyl)piperazine	52-65	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
31951912-6	2020	The largest differences were observed between the p-methoxyphenyl and p-nitrophenyl-substituted Zn(II) chlorins, undergoing loss of Zn(II) with pseudo first order rate constants of 0.0789 x 10-3 and 3.70 x 10-3 min-1, respectively.	Zinc	70-111	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
31951912-6	2020	The largest differences were observed between the p-methoxyphenyl and p-nitrophenyl-substituted Zn(II) chlorins, undergoing loss of Zn(II) with pseudo first order rate constants of 0.0789 x 10-3 and 3.70 x 10-3 min-1, respectively.	Zinc	96-102	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
32071850-11	2020	The mean (standard error) salivary caffeine clearance in the male subjects was 1.51 (0.10) mL min-1 kg-1, while that in the female subjects was 1.60 (0.07) mL min-1 kg-1 (p = 0.495).	Caffeine	35-43	CD59 molecule (CD59 blood group)	Homo sapiens	94-104
32022839-15	2020	VO2max decreased in the NTWC group at 12 months compared with baseline (17.7 [4.1] mL   min-1   kg-1, P < .001).	vo2max	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	88-100
31820144-7	2020	At 7 years of age, eGFR was significantly lower in children with prenatal alcohol exposure (134 +- 17 vs.138 +- 16 mL/min/1.73m2, p = 0.014).	Alcohols	74-81	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
32138474-3	2020	Metformin can be used safely when the estimated glomerular filtration rate (eGFR) is >= 45 mL/min/1.73 m2.	Metformin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
32138474-4	2020	If the eGFR is between 30 and 44 mL/min/1.73 m2, metformin treatment should not be started.	Metformin	49-58	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
32138474-6	2020	Metformin is contraindicated when the eGFR is < 30 mL/min/1.73 m2.	Metformin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
32138474-8	2020	During procedures involving intravenous administration of ICM, metformin should be discontinued starting the day of the procedures and up to 48 hours postprocedures if the eGFR is < 60 mL/min/1.73 m2.	Metformin	63-72	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
32244504-2	2020	We used 48% HF solution in combination with 20% oleum to keep the HF solution water-free and thus to prevent attack of the Al layer, achieving an outstanding etch rate of thermally grown SiO2 of  1 microm min-1.	Plant Oils	48-53	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
32244504-2	2020	We used 48% HF solution in combination with 20% oleum to keep the HF solution water-free and thus to prevent attack of the Al layer, achieving an outstanding etch rate of thermally grown SiO2 of  1 microm min-1.	Silicon Dioxide	187-191	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
32244975-8	2020	TGA results showed that the initial ignition temperature of furanic-glyoxal foams is ~200  C higher than that of wood, and the smaller comprehensive combustion index S (about 0.15 x 10-7 (%2 K-3 min-2)) indicates that the foam burns slowly and has poor flammability, that is, it is not easy to burn.	furanic	60-67	CD59 molecule (CD59 blood group)	Homo sapiens	195-200
32244975-8	2020	TGA results showed that the initial ignition temperature of furanic-glyoxal foams is ~200  C higher than that of wood, and the smaller comprehensive combustion index S (about 0.15 x 10-7 (%2 K-3 min-2)) indicates that the foam burns slowly and has poor flammability, that is, it is not easy to burn.	Glyoxal	68-75	CD59 molecule (CD59 blood group)	Homo sapiens	195-200
32101405-4	2020	During the polymerization process, two template molecules were introduced into the mixtures, one was the epitope of CD59 protein (YNCPNPTADCK), which was over-expressed on the surface of a great deal of the solid cancers, and the other was antitumor agent doxorubicin (DOX) to be used for chemotherapy.	Doxorubicin	256-267	CD59 molecule (CD59 blood group)	Homo sapiens	116-120
32101405-4	2020	During the polymerization process, two template molecules were introduced into the mixtures, one was the epitope of CD59 protein (YNCPNPTADCK), which was over-expressed on the surface of a great deal of the solid cancers, and the other was antitumor agent doxorubicin (DOX) to be used for chemotherapy.	Doxorubicin	269-272	CD59 molecule (CD59 blood group)	Homo sapiens	116-120
32185543-0	2020	CD59 receptor targeted delivery of miRNA-1284 and cisplatin-loaded liposomes for effective therapeutic efficacy against cervical cancer cells.	mirna-1284	35-45	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
32185543-0	2020	CD59 receptor targeted delivery of miRNA-1284 and cisplatin-loaded liposomes for effective therapeutic efficacy against cervical cancer cells.	Cisplatin	50-59	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
32185543-2	2020	In this study, we have designed the CD59sp-conjugated miRNA-1284/cisplatin(CDDP)-loaded liposomes for the enhanced therapeutic effect against cervical cancers.	mirna-1284	54-64	CD59 molecule (CD59 blood group)	Homo sapiens	36-40
32185543-2	2020	In this study, we have designed the CD59sp-conjugated miRNA-1284/cisplatin(CDDP)-loaded liposomes for the enhanced therapeutic effect against cervical cancers.	Cisplatin	65-74	CD59 molecule (CD59 blood group)	Homo sapiens	36-40
32185543-2	2020	In this study, we have designed the CD59sp-conjugated miRNA-1284/cisplatin(CDDP)-loaded liposomes for the enhanced therapeutic effect against cervical cancers.	Cisplatin	75-79	CD59 molecule (CD59 blood group)	Homo sapiens	36-40
31923509-3	2020	The nonisothermal melt crystallization peak temperature obviously increased from 18.8  C for neat PCL to 30.9  C for the PCL/NC nanocomposite with 10 wt% NC content at a cooling rate of 10  C min-1; moreover, the half-time isothermal crystallization at 40  C significantly decreased from 12.2 min for neat PCL to 2.0 min.	poly(epsilon-caprolactone)-poly(oxyethylene)-poly(epsilon-caprolactone)	121-124	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
31923509-3	2020	The nonisothermal melt crystallization peak temperature obviously increased from 18.8  C for neat PCL to 30.9  C for the PCL/NC nanocomposite with 10 wt% NC content at a cooling rate of 10  C min-1; moreover, the half-time isothermal crystallization at 40  C significantly decreased from 12.2 min for neat PCL to 2.0 min.	poly(epsilon-caprolactone)-poly(oxyethylene)-poly(epsilon-caprolactone)	121-124	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
32043995-4	2020	The efficiency of electrooxidation of l-ascorbic acid increased as the flow rate decreased and was close to 100% when the flow rate was below 50 muL min-1, which is a common flow rate in microbore or capillary liquid chromatography.	Ascorbic Acid	38-53	CD59 molecule (CD59 blood group)	Homo sapiens	149-154
32131418-6	2020	An increased urinary level of Cd to the median level of 0.38 mug/L (0.44 mug/g of creatinine) was associated with a decrease in the eGFR by 4.94 mL/min/1.73 m2 (p = 0.011).	Cadmium	30-32	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
32131418-6	2020	An increased urinary level of Cd to the median level of 0.38 mug/L (0.44 mug/g of creatinine) was associated with a decrease in the eGFR by 4.94 mL/min/1.73 m2 (p = 0.011).	Creatinine	82-92	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
31594384-4	2020	METHODS: In 16 women with migraine without aura and 10 age- and gender-matched controls without headache, intravenous nitroglycerin (0.5 microg kg-1 min-1) was administered.	Nitroglycerin	118-131	CD59 molecule (CD59 blood group)	Homo sapiens	149-154
32065769-11	2020	Change in VO2peak ranged from -2.7 to 4.1 mL O2 kg-1 min-1 and from -3.6 to 5.1 mL O2 kg-1 min-1 in LET and NLET, respectively.	Oxygen	11-13	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
31744698-8	2020	The activation energy (Ea) and turn over frequency (TOF) for the reduction of 4-NP to 4-AP catalyzed by CuFeCN system are determined as 24.6 kJ mol-1 and 36.93 min-1, respectively, which are both significantly more superior than most of reported catalysts in literatures.	4-nitrophenol	78-82	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
31744698-8	2020	The activation energy (Ea) and turn over frequency (TOF) for the reduction of 4-NP to 4-AP catalyzed by CuFeCN system are determined as 24.6 kJ mol-1 and 36.93 min-1, respectively, which are both significantly more superior than most of reported catalysts in literatures.	4-aminophenol	86-90	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
31744698-8	2020	The activation energy (Ea) and turn over frequency (TOF) for the reduction of 4-NP to 4-AP catalyzed by CuFeCN system are determined as 24.6 kJ mol-1 and 36.93 min-1, respectively, which are both significantly more superior than most of reported catalysts in literatures.	osmium ferricyanide	104-110	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
32028687-4	2020	For oil containing 0.1 wt% graphene at a rotational speed of 3000 r min-1 and 40 N loads, the average friction coefficient was reduced by 76.33%.	Graphite	27-35	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
32028687-6	2020	For oil containing 0.05 wt% graphene at a lower rotational speed of 500 r min-1 and a higher load of 140 N, the temperature rise was reduced by 19.76%.	Graphite	28-36	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
32097995-3	2020	Metformin can be used safely when the estimated glomerular filtration rate (eGFR) is >=45 mL/min/1.73 m2.	Metformin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
32097995-4	2020	If the eGFR is between 30 and 44 mL/min/1.73 m2, metformin treatment should not be started.	Metformin	49-58	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
32097995-6	2020	Metformin is contraindicated when the eGFR is <30 mL/min/1.73 m2.	Metformin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	53-58
32097995-8	2020	During procedures involving intravenous administration of ICM, metformin should be discontinued starting the day of the procedures and up to 48 hours post-procedures if the eGFR is <60 mL/min/1.73 m2.	Metformin	63-72	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
31079551-6	2020	MFO was significantly greater in the cold vs. warm during the treadmill exercise (0.66 +- 0.31 vs. 0.43 +- 0.23 g min-1; p = 0.02) but not during cycling (0.45 +- 0.24 vs. 0.29 +- 0.11 g min-1; p = 0.076).	mfo	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
31079551-6	2020	MFO was significantly greater in the cold vs. warm during the treadmill exercise (0.66 +- 0.31 vs. 0.43 +- 0.23 g min-1; p = 0.02) but not during cycling (0.45 +- 0.24 vs. 0.29 +- 0.11 g min-1; p = 0.076).	mfo	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
31079551-7	2020	MFO was also greater during treadmill vs. cycling exercise, irrespective of ambient temperature (0.57 g min-1 vs. 0.37 g min-1; p = 0.04).	mfo	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
31079551-7	2020	MFO was also greater during treadmill vs. cycling exercise, irrespective of ambient temperature (0.57 g min-1 vs. 0.37 g min-1; p = 0.04).	mfo	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
31701353-6	2020	Salidroside also prevented the decreases in CD46 and CD59, and the increases in VCAM-1, ICAM-1, P-selectin and E-selectin caused by OGD/R in HUVEC, which were associated with decreasing LDH release and increasing Bcl-2/Bax ratio.	rhodioloside	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
31701353-10	2020	These results suggest endothelium is an important locus of inhibition of complement by salidroside, restoring an anti-inflammatory endothelial phenotype after oxidative stress, partly by inhibiting classical complement activation and partly by increasing CD46 and CD59, in association with anti-apoptotic effects.	rhodioloside	87-98	CD59 molecule (CD59 blood group)	Homo sapiens	264-268
31916555-1	2020	Alloyed bimetallic Pd-Ru nanocatalysts prepared by in situ reduction of a mixture of a Ru(iii) source and a Pd(ii)@alkyne-PVA aerogel and characterized by TEM and XPS exhibit very highly catalytic activity towards hydrogen release from ammonia borane hydrolysis with a TOF value of 578.2 molH2 molcat-1 min-1.	Ruthenium	19-24	CD59 molecule (CD59 blood group)	Homo sapiens	303-308
31869482-1	2020	A 12 kg infant was given intravenous dexmedetomidine 0.2 microg.kg-1 .min-1 as an adjunct for general anaesthesia.	Dexmedetomidine	37-52	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
31606879-11	2020	Oxygen cost improvements were larger in participants with higher VO2max (>= 52.3 ml kg-1 min-1) (0.39 [95% CI 0.06, 0.72], Z = 2.34, p = 0.02), and in programs greater or equal to 8 weeks (0.35 [95% CI 0.03, 0.67], Z = 2.13, p = 0.03).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
32063866-9	2020	Estimated maximal oxygen uptake was ~52.5 ml kg-1 min-1 for females and 62.6 ml kg-1 min-1 for males (p &lt; 0.0001).	Oxygen	18-24	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
31916555-1	2020	Alloyed bimetallic Pd-Ru nanocatalysts prepared by in situ reduction of a mixture of a Ru(iii) source and a Pd(ii)@alkyne-PVA aerogel and characterized by TEM and XPS exhibit very highly catalytic activity towards hydrogen release from ammonia borane hydrolysis with a TOF value of 578.2 molH2 molcat-1 min-1.	Ruthenium	22-24	CD59 molecule (CD59 blood group)	Homo sapiens	303-308
31949174-4	2020	Maximal oxygen consumption ([Formula: see text]) in ml min-1 kg-1 was estimated.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	55-65
31570193-7	2020	Using positive lithium cationisation with 0.5 mM lithium chloride in methanol as the make-up solvent, delivered at a flow rate of 0.02 mL min-1, the levoglucosan response was improved by factors of 100 and 10, comparing to negative ionisation and positive sodium cationisation, respectively.	1,6-anhydro-beta-glucopyranose	149-161	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
31815424-5	2020	With the synergy of a GDE flow-cell and 1 M KOH catholyte, a current density of ~200 mA cm-2 was reached at -1.17 V (RHE), which enabled a CO yield efficiency record of 3.05 mg min-1 (CO2/15 ml min-1 with 2 cm2 electrode).	potassium hydroxide	44-47	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
31815424-5	2020	With the synergy of a GDE flow-cell and 1 M KOH catholyte, a current density of ~200 mA cm-2 was reached at -1.17 V (RHE), which enabled a CO yield efficiency record of 3.05 mg min-1 (CO2/15 ml min-1 with 2 cm2 electrode).	potassium hydroxide	44-47	CD59 molecule (CD59 blood group)	Homo sapiens	194-199
31815424-5	2020	With the synergy of a GDE flow-cell and 1 M KOH catholyte, a current density of ~200 mA cm-2 was reached at -1.17 V (RHE), which enabled a CO yield efficiency record of 3.05 mg min-1 (CO2/15 ml min-1 with 2 cm2 electrode).	Carbon Dioxide	139-141	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
31815424-5	2020	With the synergy of a GDE flow-cell and 1 M KOH catholyte, a current density of ~200 mA cm-2 was reached at -1.17 V (RHE), which enabled a CO yield efficiency record of 3.05 mg min-1 (CO2/15 ml min-1 with 2 cm2 electrode).	Carbon Dioxide	139-141	CD59 molecule (CD59 blood group)	Homo sapiens	194-199
31916065-7	2020	The beneficial effects of thiazide diuretics are reduced when the glomerular filtration rate is reduced to less than 40 mL/min/1.73 m2.	Thiazides	26-34	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
31774275-7	2020	Under an adverse condition (pH 9.0), the mass transfer was ~2.5 times higher than that in the pore-free one (0.10 min-1 vs. 0.04 min-1), ensuring the possibility of diffusing phosphate in further contact with these active sites.	Phosphates	175-184	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
31774275-7	2020	Under an adverse condition (pH 9.0), the mass transfer was ~2.5 times higher than that in the pore-free one (0.10 min-1 vs. 0.04 min-1), ensuring the possibility of diffusing phosphate in further contact with these active sites.	Phosphates	175-184	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
32238710-7	2020	Moreover, kinetic analysis of the inactivation revealed that sesamin showed a preincubation time- and concentration-dependent inhibition of CYP4F2 activity yielding a maximal inactivation rate constant (kinact) value of 0.354 min-1 and half-maximal inhibitory concentration (KI) value of 1.12 microM.	sesamin	61-68	CD59 molecule (CD59 blood group)	Homo sapiens	226-231
31155645-4	2020	Levosimendan infusion was started at a dose of 0.1 microg kg-1 min-1 for a maximum of 48 h without a bolus.	Simendan	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
32036364-3	2020	OBJECTIVE: The aim of this study was to investigate clinical (contrast-induced acute kidney injury [CI-AKI]) and subclinical CI-AKI (SCI-AKI) after intra-arterial administration of Iodixanol and Iopamidol in patients with an estimated glomerular filtration rate (eGFR) >=60 mL/min/1.73 m2.	iodixanol	181-190	CD59 molecule (CD59 blood group)	Homo sapiens	277-282
31524615-3	2020	The procedure to remove arsenic was optimized as follows: initial H+ concentration of 5 mol L-1, Cu-to-As molar ratio of 8, Cl-to-As molar ratio of 10, a reaction temperature of 60  C, copper powder particle size of 68-24 mum, and a stirring speed of 300 r min-1.	Arsenic	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	257-262
33456078-9	2020	There were differences in the sites and intensity of membrane protectin expression exclusively on the luminal surfaces in pSS; on the luminal and, partially, antiluminal surface in non-specific inflammation, and on the entire cell surface in unaffected salivary glands.	Phenobarbital	102-109	CD59 molecule (CD59 blood group)	Homo sapiens	62-71
31846386-4	2020	The increase in the catalyst concentration leads to a decrease in the degradation rate constant, which is the most pronounced in the ZnO/TiO2 and ranges from 0.47 (6) min-1 to 0.25 (3) min-1.	Zinc	133-136	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
31846386-4	2020	The increase in the catalyst concentration leads to a decrease in the degradation rate constant, which is the most pronounced in the ZnO/TiO2 and ranges from 0.47 (6) min-1 to 0.25 (3) min-1.	Zinc	133-136	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
31846386-4	2020	The increase in the catalyst concentration leads to a decrease in the degradation rate constant, which is the most pronounced in the ZnO/TiO2 and ranges from 0.47 (6) min-1 to 0.25 (3) min-1.	Titanium	137-141	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
31846386-4	2020	The increase in the catalyst concentration leads to a decrease in the degradation rate constant, which is the most pronounced in the ZnO/TiO2 and ranges from 0.47 (6) min-1 to 0.25 (3) min-1.	Titanium	137-141	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
33456078-9	2020	There were differences in the sites and intensity of membrane protectin expression exclusively on the luminal surfaces in pSS; on the luminal and, partially, antiluminal surface in non-specific inflammation, and on the entire cell surface in unaffected salivary glands.	pss	122-125	CD59 molecule (CD59 blood group)	Homo sapiens	62-71
31295684-7	2019	As a result, the degradation rate of optimized modified carbon nitride sample for sulfamethazine was 0.1062 min-1, which was almost 12 times than that of carbon nitride (0.0086 min-1).	cyanogen	56-70	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
31295684-7	2019	As a result, the degradation rate of optimized modified carbon nitride sample for sulfamethazine was 0.1062 min-1, which was almost 12 times than that of carbon nitride (0.0086 min-1).	cyanogen	56-70	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
31295684-7	2019	As a result, the degradation rate of optimized modified carbon nitride sample for sulfamethazine was 0.1062 min-1, which was almost 12 times than that of carbon nitride (0.0086 min-1).	Sulfamethazine	82-96	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
31295684-7	2019	As a result, the degradation rate of optimized modified carbon nitride sample for sulfamethazine was 0.1062 min-1, which was almost 12 times than that of carbon nitride (0.0086 min-1).	Sulfamethazine	82-96	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
31295684-7	2019	As a result, the degradation rate of optimized modified carbon nitride sample for sulfamethazine was 0.1062 min-1, which was almost 12 times than that of carbon nitride (0.0086 min-1).	cyanogen	154-168	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
31295684-7	2019	As a result, the degradation rate of optimized modified carbon nitride sample for sulfamethazine was 0.1062 min-1, which was almost 12 times than that of carbon nitride (0.0086 min-1).	cyanogen	154-168	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
31886324-7	2020	LL-37 co-stained with integrin alpha3, tetraspanin CD9, GPI-linked CD59 and costimulatory molecule CD276 (B7-H3) in these vesicles.	Glycosylphosphatidylinositols	56-59	CD59 molecule (CD59 blood group)	Homo sapiens	67-71
32237392-3	2019	5 mmol L-1 ammonium dibasic phosphate( gradient elution) at a flow rate of 1 m L min-1.	l-1 ammonium dibasic phosphate	7-37	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
29888986-4	2019	The airflow rate also affected the process, since H2S concentration in the biogas was higher at 0.1 mL air.min-1 than at 0.3 mL air.min-1.	Hydrogen Sulfide	50-53	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
29888986-4	2019	The airflow rate also affected the process, since H2S concentration in the biogas was higher at 0.1 mL air.min-1 than at 0.3 mL air.min-1.	Hydrogen Sulfide	50-53	CD59 molecule (CD59 blood group)	Homo sapiens	132-137
31520959-2	2019	From the results it was evident that the stavudine degradation followed pseudo-first-order kinetics, with the values of the degradation rate constant and half-life being 0.24 min-1 and 2.9 min, respectively, at a current density of 8 mA cm-2.	Stavudine	41-50	CD59 molecule (CD59 blood group)	Homo sapiens	175-188
31612365-4	2019	Therefore, the aim of the study was to investigate influence of NADPH oxidase inhibition on the expression of IL-6, IL-8, TNF, TSLP, CD59, and PPAR-gamma in vitro.	NADP	64-69	CD59 molecule (CD59 blood group)	Homo sapiens	133-137
31612365-8	2019	The time-response and dose-response study showed that apocynin significantly influenced the relative expression of chosen genes (IL-6, IL-8, TNF, PPAR-gamma, TSLP, and CD59).	acetovanillone	54-62	CD59 molecule (CD59 blood group)	Homo sapiens	168-172
31531807-6	2019	Ritonavir-boosted paritaprevir/ombitasvir was prescribed to five recipients with Crcl &lt; 30 mL/min/1.73 m2.	Ritonavir	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
31531807-6	2019	Ritonavir-boosted paritaprevir/ombitasvir was prescribed to five recipients with Crcl &lt; 30 mL/min/1.73 m2.	paritaprevir	18-30	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
31657122-4	2019	The electrochemical results reveal that FeS2 /CFP achieves a high Faradaic efficiency (FE) of  14.14% and NH3 yield rate of  0.096 microg min-1 at -0.6 V versus RHE electrode in 0.25 m LiClO4 .	greigite	40-44	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
31657122-4	2019	The electrochemical results reveal that FeS2 /CFP achieves a high Faradaic efficiency (FE) of  14.14% and NH3 yield rate of  0.096 microg min-1 at -0.6 V versus RHE electrode in 0.25 m LiClO4 .	Ammonia	106-109	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
31657122-6	2019	With near-infrared laser irradiation (808 nm), the NH3 yield rate of the FeS2 /CFP catalyst can be slightly improved to 0.1 microg min-1 with high FE of 14.57%.	Ammonia	51-54	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
31657122-6	2019	With near-infrared laser irradiation (808 nm), the NH3 yield rate of the FeS2 /CFP catalyst can be slightly improved to 0.1 microg min-1 with high FE of 14.57%.	greigite	73-77	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
31849698-16	2019	O  2    (ml kg-1 min-1), in the supine compared with the upright bicycle test.	Superoxides	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	17-22
31858035-2	2019	This method realizes rapid and controllable fabrication of uniform graphene microspheres with up to 800 muL min-1 (ca.	Graphite	67-75	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
31344571-5	2019	For instance, degradation rates of STZ increased from 0.3 x 10-3 to 19.5 x 10-3 min-1 as the temperature was increased from 30 to 60  C. Under the same experimental conditions, the degradation rates of SAs followed the order of SIX &gt; SMX   STZ &gt; SMT, which was in accordance with decay rates of their R-NH2 moieties.	Sulfathiazole	35-38	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
31803717-3	2019	It"s found that bracelet-like nanoplatelets were obtained at x = 0.4 and exhibit highest catalytic performance with turnover frequency of 33.43 molhydrogen min-1  mol cat - 1   , which much higher than those of most of CuNi-based catalysts in the literature.	Nickel	219-223	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
31437644-6	2019	The photodegradation followed the first-order kinetics with degradation rate constants (k) ranging between 1.19 x 10-1 and 2.52 x 10-1 min-1 at 20-80 mg L-1 ZnO nanowires.	Zinc Oxide	157-160	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
31437644-8	2019	With the addition of HCO3- (1-5 mM) or Suwannee River natural organic matter (SRNOM, 2-10 mg L-1), the k values were substantially decreased by a factor of 1.8-70 to 1.69 x 10-3-6.67 x 10-2 min-1, probably due to screening effect of HCO3- or SRNOM sorbed on ZnO nanowires and scavenging of free radicals by free HCO3- or SRNOM in solution.	Bicarbonates	21-25	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
31039902-3	2019	The Co NPs/MXene exhibited excellent catalytic performance for the hydrolysis of ammonia borane with TOF value of 39.9 molH2 mol-1cat min-1 at 323 K. The enhanced catalytic property was mainly due to the ultrafine nanoparticles formed on MXene surface.	Ammonia borane	81-95	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
31039902-3	2019	The Co NPs/MXene exhibited excellent catalytic performance for the hydrolysis of ammonia borane with TOF value of 39.9 molH2 mol-1cat min-1 at 323 K. The enhanced catalytic property was mainly due to the ultrafine nanoparticles formed on MXene surface.	mxene	11-16	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
31660882-8	2019	A cut-off value for optimal sensitivity and specificity of salivary creatinine to diagnose CKD with glomerular filtration rate (GFR) &lt; 60 mL/min/1.73 m2 was obtained.	Creatinine	68-78	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
31665070-11	2019	The maximal oxygen uptake (mean +- SD) measured at baseline was 54.7 +- 4.1 ml min- 1 kg- 1.	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	79-91
31655603-8	2019	RESULTS: Exogenous carbohydrate oxidation contributed 27.6 +- 6.6% to the total energy yield with CHO-HG and the peak exogenous carbohydrate oxidation rate reached 1.33 +- 0.27 g min- 1.	Carbohydrates	19-31	CD59 molecule (CD59 blood group)	Homo sapiens	179-185
31655603-8	2019	RESULTS: Exogenous carbohydrate oxidation contributed 27.6 +- 6.6% to the total energy yield with CHO-HG and the peak exogenous carbohydrate oxidation rate reached 1.33 +- 0.27 g min- 1.	Carbohydrates	128-140	CD59 molecule (CD59 blood group)	Homo sapiens	179-185
31207485-3	2019	The degradation apparent rate constant k of dr-MoO3 is as large as 5.9 x 10-2 min-1, which is ~6.6 times higher than commercial alpha-MoO3 (com-MoO3).	dr-moo3	44-51	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
31207485-3	2019	The degradation apparent rate constant k of dr-MoO3 is as large as 5.9 x 10-2 min-1, which is ~6.6 times higher than commercial alpha-MoO3 (com-MoO3).	alpha-moo3	128-138	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
31207485-3	2019	The degradation apparent rate constant k of dr-MoO3 is as large as 5.9 x 10-2 min-1, which is ~6.6 times higher than commercial alpha-MoO3 (com-MoO3).	com-moo3	140-148	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
31605522-6	2019	RESULTS: DL had the highest maximal oxygen uptake (42.3 mL min-1 kg-1) ever observed for a female older than 80 years of age, which gave her a remarkable physiological age (27 y).	Oxygen	36-42	CD59 molecule (CD59 blood group)	Homo sapiens	59-69
31658648-8	2019	CO2 conversion and CH4 selectivity over Ru@UiO-66 reached 72.2% and 95.4% under 13.0 W of discharge power and a 30 mL min-1 gas flow rate ( V H 2 : V C O 2 = 4 : 1 ), respectively.	Carbon Dioxide	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
31658648-8	2019	CO2 conversion and CH4 selectivity over Ru@UiO-66 reached 72.2% and 95.4% under 13.0 W of discharge power and a 30 mL min-1 gas flow rate ( V H 2 : V C O 2 = 4 : 1 ), respectively.	JMV 641	19-22	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
31658648-8	2019	CO2 conversion and CH4 selectivity over Ru@UiO-66 reached 72.2% and 95.4% under 13.0 W of discharge power and a 30 mL min-1 gas flow rate ( V H 2 : V C O 2 = 4 : 1 ), respectively.	Ruthenium	40-42	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
31658648-8	2019	CO2 conversion and CH4 selectivity over Ru@UiO-66 reached 72.2% and 95.4% under 13.0 W of discharge power and a 30 mL min-1 gas flow rate ( V H 2 : V C O 2 = 4 : 1 ), respectively.	T-66	43-49	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
31512693-3	2019	First, we confirmed the osmotic flow across the lipid bilayer and calculated the osmotic flow velocity to be 8.5 fL min-1 mum-2 when a salt concentration difference was applied to the lipid bilayer.	Salts	135-139	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
31495858-5	2019	The device could effectively homogenize DI water and fluorescein within a mixing length of 25.2 mum up to a flow rate of 116 muL min-1 at a driving voltage of 40 Vpp, corresponding to a mixing time of 0.8 ms.	Water	43-48	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
31558088-6	2021	Theophylline administration was associated with significantly decreased serum creatinine levels (MD: -0.57 mg/dl, 95% CI: [-0.68, -0.46]) and elevated glomerular filtration rate (MD: 13.79 ml/min/1.73 m2, 95% CI: [11.91, 15.68]) in the third day of life.	Theophylline	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	192-197
31324934-8	2019	There was 180-fold variation in the rate of 5-FU uptake into BMC (0.10-17.86 pmol min-1 105 viable cells-1) across the 34 subjects (healthy participants N = 24, cancer patients N = 10).	Fluorouracil	44-48	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
31324934-8	2019	There was 180-fold variation in the rate of 5-FU uptake into BMC (0.10-17.86 pmol min-1 105 viable cells-1) across the 34 subjects (healthy participants N = 24, cancer patients N = 10).	bmc	61-64	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
31321747-2	2019	Individuals already treated with canagliflozin or empagliflozin who demonstrate renal decline may continue treatment until eGFR reaches &lt; 45 mL/min/1.73 m2".	Canagliflozin	33-46	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
31321747-2	2019	Individuals already treated with canagliflozin or empagliflozin who demonstrate renal decline may continue treatment until eGFR reaches &lt; 45 mL/min/1.73 m2".	empagliflozin	50-63	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
31454521-0	2019	Combination treatment with lipoteichoic acids isolated from Lactobacillus plantarum and Staphylococcus aureus alleviates atopic dermatitis via upregulation of CD55 and CD59.	lipoteichoic acid	27-45	CD59 molecule (CD59 blood group)	Homo sapiens	168-172
31430126-4	2019	The highly enhanced domain growth rate (~37 nm min-1) and the quick nucleation rate (~1200 nuclei min-1 cm-2) both account for this high productivity of graphene film.	Graphite	153-161	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
31313410-5	2019	RESULTS: On Day-A, effective renal plasma flow increased by 68 [26-197] mL/min/1.73 m2 during exenatide vs placebo infusion (+17%; P = .015).	Exenatide	94-103	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
31430126-4	2019	The highly enhanced domain growth rate (~37 nm min-1) and the quick nucleation rate (~1200 nuclei min-1 cm-2) both account for this high productivity of graphene film.	Graphite	153-161	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
31357262-9	2019	In patients with a GFR &lt; 60 mL/min/1.73 m2, uric acid levels correlated positively with the PRF thickness (P &lt; 0.05).	Uric Acid	47-56	CD59 molecule (CD59 blood group)	Homo sapiens	34-39
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	Hydrogen	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	216-221
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	Hydrogen	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	Hydrogen	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	Norfloxacin	122-133	CD59 molecule (CD59 blood group)	Homo sapiens	216-221
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	Norfloxacin	122-133	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	Norfloxacin	122-133	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	snnb2o6	55-62	CD59 molecule (CD59 blood group)	Homo sapiens	216-221
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	snnb2o6	55-62	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	snnb2o6	55-62	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	bismuth wolframate	63-69	CD59 molecule (CD59 blood group)	Homo sapiens	216-221
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	bismuth wolframate	63-69	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
31176051-6	2019	As expected, the hydrogen bond-assisted 2D/2D Z-scheme SnNb2O6/Bi2WO6 system results in an outstanding improvement of the norfloxacin (NOR) photodegradation efficiency, and the degradation rate constant (4.06 x 10-2 min-1) is 9 and 2 times higher than those of SnNb2O6 (4.33 x 10-3 min-1), and Bi2WO6 (1.70 x 10-2 min-1), respectively.	bismuth wolframate	63-69	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
31160095-5	2019	A sheath liquid composed of isopropanol - water - acetic acid with a flow rate of 10 muL min-1 and mild MS conditions allowed optimal signal intensities.	2-Propanol	28-39	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
31160095-5	2019	A sheath liquid composed of isopropanol - water - acetic acid with a flow rate of 10 muL min-1 and mild MS conditions allowed optimal signal intensities.	Water	42-47	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
31319402-8	2019	CONCLUSIONS: The authors conclude that GT3X (cut-point of &lt;100 counts min-1) overestimated sedentary time of free-living activities and did not detect changes resulting from a classroom standing desk intervention in adolescents.	gt3x	39-43	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
31514342-1	2019	Systemic oxygen delivery (DO2) is a more comprehensive marker of patient status than arterial oxygen saturation (SaO2), and DO2 in the range of 330-500 mL min-1 is reportedly adequate during anaesthesia.	do2	124-127	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
31121346-4	2019	The results indicated that a carbon-doped g-C3N4 with an optimum dopant content (MCB0.07) displayed the best photocatalytic activity for the total trihalomethanes (TTHM) and total haloacetonitriles (THAN), with the reaction rate constant of 11.6 and 10.4 (10-3 min-1), respectively.	Carbon	29-35	CD59 molecule (CD59 blood group)	Homo sapiens	261-266
31121346-4	2019	The results indicated that a carbon-doped g-C3N4 with an optimum dopant content (MCB0.07) displayed the best photocatalytic activity for the total trihalomethanes (TTHM) and total haloacetonitriles (THAN), with the reaction rate constant of 11.6 and 10.4 (10-3 min-1), respectively.	g-c3n4	42-48	CD59 molecule (CD59 blood group)	Homo sapiens	261-266
31121346-4	2019	The results indicated that a carbon-doped g-C3N4 with an optimum dopant content (MCB0.07) displayed the best photocatalytic activity for the total trihalomethanes (TTHM) and total haloacetonitriles (THAN), with the reaction rate constant of 11.6 and 10.4 (10-3 min-1), respectively.	dopant	65-71	CD59 molecule (CD59 blood group)	Homo sapiens	261-266
31121346-4	2019	The results indicated that a carbon-doped g-C3N4 with an optimum dopant content (MCB0.07) displayed the best photocatalytic activity for the total trihalomethanes (TTHM) and total haloacetonitriles (THAN), with the reaction rate constant of 11.6 and 10.4 (10-3 min-1), respectively.	Trihalomethanes	147-162	CD59 molecule (CD59 blood group)	Homo sapiens	261-266
31854882-3	2019	When a phosphorus source was and was not added, the optimum conditions for recovering phosphorus were pH=9.5, N:P=0.8, and Mg:P=1.8 and pH=9.5, Mg:P=1.6, and speed=200 r min-1, respectively.	Phosphorus	86-96	CD59 molecule (CD59 blood group)	Homo sapiens	170-175
30776254-4	2019	Taurine supplementation increased time to exhaustion by 10% (25.16 min vs. 22.43 min, p = 0.040), end sweat rate by 12.7% (687 nL min-1 vs. 600 nL min-1, p = 0.034) and decreased B[La] by 16.5% (5.75 mmol L-1 vs. 6.85 mmol L-1, p = 0.033).	Taurine	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
30776254-4	2019	Taurine supplementation increased time to exhaustion by 10% (25.16 min vs. 22.43 min, p = 0.040), end sweat rate by 12.7% (687 nL min-1 vs. 600 nL min-1, p = 0.034) and decreased B[La] by 16.5% (5.75 mmol L-1 vs. 6.85 mmol L-1, p = 0.033).	Taurine	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
31075550-6	2019	High plasma selenium and low red blood cell lead levels also interacted to increase the eGFR (20.70, 15.56-26.01 mL/min/1.73 m2).	Selenium	12-20	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
31280722-4	2019	The adsorption behaviour was modelled using the Langmuir isotherm model and the phosphonate anchoring group was found to have the highest affinity for NiO (6.65 x 104 M-1) and the fastest rate of adsorption (2.46 x 107 cm2 mol-1 min-1).	Organophosphonates	80-91	CD59 molecule (CD59 blood group)	Homo sapiens	229-234
31450763-6	2019	Digital microscopy images revealed that the as-formed alginate films at the flow rate of 100 microL min-1 and the N2 gas pressure of 0.8 bar have highly monodisperse microbubbles with a polydispersity index (PDI) of approximately 6.5%.	Alginates	54-62	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	Benzophenone oxime	196-214	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	Benzophenone oxime	196-214	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	Benzophenone oxime	196-214	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	Benzophenone oxime	196-214	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	benzophenone	196-208	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	benzophenone	196-208	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	benzophenone	196-208	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	benzophenone	196-208	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	4-anisaldehyde	267-288	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	4-anisaldehyde	267-288	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	4-anisaldehyde	267-288	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	4-anisaldehyde	267-288	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	anisyl alcohol	294-317	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	anisyl alcohol	294-317	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	anisyl alcohol	294-317	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	anisyl alcohol	294-317	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	enaminone	343-352	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	enaminone	343-352	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	enaminone	343-352	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
32110301-6	2019	Then, using the present method, the scale-up of the reactions was achieved at an isolated rate of 19 mg min-1 for the product of the Claisen-Schmidt condensation, 21 mg min-1 for the synthesis of benzophenone oxime from benzophenone, 31 mg min-1 for the synthesis of 4-methoxybenzaldehyde from 4-methoxybenzyl alcohol, and 40 mg min-1 for the enaminone product of the Eschenmoser coupling reaction.	enaminone	343-352	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
31216111-4	2019	The photocatalytic degradation of Rhodamine B (RhB) molecules is approximately 100 % with TpSD and its pseudo-first-order rate constant is 0.0770 min-1 , which is the highest among all reported non-metallic photocatalysts.	rhodamine B	34-45	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
31216111-4	2019	The photocatalytic degradation of Rhodamine B (RhB) molecules is approximately 100 % with TpSD and its pseudo-first-order rate constant is 0.0770 min-1 , which is the highest among all reported non-metallic photocatalysts.	rhodamine B	47-50	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
31405218-6	2019	The degradation efficiency of Rhodamine B (RhB, 20 mg L-1) can reach nearly 100% within 25 min, the apparent rate constant (kapp/min-1) is approximately 40.06 and 3.87 times higher than that of pure CuS and Bi2WO6, respectively.	rhodamine B	30-41	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
31405218-6	2019	The degradation efficiency of Rhodamine B (RhB, 20 mg L-1) can reach nearly 100% within 25 min, the apparent rate constant (kapp/min-1) is approximately 40.06 and 3.87 times higher than that of pure CuS and Bi2WO6, respectively.	rhodamine B	43-46	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
31405218-6	2019	The degradation efficiency of Rhodamine B (RhB, 20 mg L-1) can reach nearly 100% within 25 min, the apparent rate constant (kapp/min-1) is approximately 40.06 and 3.87 times higher than that of pure CuS and Bi2WO6, respectively.	cupric sulfide	199-202	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
31943952-2	2019	The highest TOF (turnover frequency) was obtained for the hydrosilylation of 2-octanone with phenylsilane (4190 min-1 ).	2-octanone	77-87	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
31943952-2	2019	The highest TOF (turnover frequency) was obtained for the hydrosilylation of 2-octanone with phenylsilane (4190 min-1 ).	Phenylsilane	93-105	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
31943952-4	2019	The TOF of the hydrosilylation of 4-chloroacetophenone with diphenylsilane was quite low (30 min-1 ), however the addition of a catalytic amount of Lewis base, especially pyridine, dramatically accelerated this hydrosilylation (980 min-1 ).	4-chloroacetophenone	34-54	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
31943952-4	2019	The TOF of the hydrosilylation of 4-chloroacetophenone with diphenylsilane was quite low (30 min-1 ), however the addition of a catalytic amount of Lewis base, especially pyridine, dramatically accelerated this hydrosilylation (980 min-1 ).	4-chloroacetophenone	34-54	CD59 molecule (CD59 blood group)	Homo sapiens	232-237
31943952-4	2019	The TOF of the hydrosilylation of 4-chloroacetophenone with diphenylsilane was quite low (30 min-1 ), however the addition of a catalytic amount of Lewis base, especially pyridine, dramatically accelerated this hydrosilylation (980 min-1 ).	Diphenylsilane	60-74	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
31943952-4	2019	The TOF of the hydrosilylation of 4-chloroacetophenone with diphenylsilane was quite low (30 min-1 ), however the addition of a catalytic amount of Lewis base, especially pyridine, dramatically accelerated this hydrosilylation (980 min-1 ).	Diphenylsilane	60-74	CD59 molecule (CD59 blood group)	Homo sapiens	232-237
31943952-4	2019	The TOF of the hydrosilylation of 4-chloroacetophenone with diphenylsilane was quite low (30 min-1 ), however the addition of a catalytic amount of Lewis base, especially pyridine, dramatically accelerated this hydrosilylation (980 min-1 ).	pyridine	171-179	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
31943952-4	2019	The TOF of the hydrosilylation of 4-chloroacetophenone with diphenylsilane was quite low (30 min-1 ), however the addition of a catalytic amount of Lewis base, especially pyridine, dramatically accelerated this hydrosilylation (980 min-1 ).	pyridine	171-179	CD59 molecule (CD59 blood group)	Homo sapiens	232-237
31271399-7	2019	Using this approach, we have been able to generate 4-12 nm Ag sMNPs with thermal pulses as short as 35 ms. Fast heating timescales employed in this approach allow for the scalable manufacturing of high yields of metal sMNPs, which we estimate to be around 1 g min-1.	Metals	212-217	CD59 molecule (CD59 blood group)	Homo sapiens	260-265
31330801-6	2019	A significant difference in the mean change in eGFR with respect to serum urate target achievement was shown in individuals with chronic kidney disease stage 3 (-0.35 +- 3.87 mL/min/1.73 m2 vs. 5.33 +- 11.64 mL/min/1.73 m2, p = 0.019).	Uric Acid	74-79	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
31330801-6	2019	A significant difference in the mean change in eGFR with respect to serum urate target achievement was shown in individuals with chronic kidney disease stage 3 (-0.35 +- 3.87 mL/min/1.73 m2 vs. 5.33 +- 11.64 mL/min/1.73 m2, p = 0.019).	Uric Acid	74-79	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
31299992-8	2019	Their simulations show that superficial flow velocities of about 50 microm min-1 are needed to produce changes in TMA+ fluxes comparable to those accounted for by diffusion.	4,4-dimethylcholesta-8,14-dien-3-ol	114-118	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
31308407-10	2019	The kinetics investigations revealed 2.55 and 4.04 times increased rate of reactions compared to pristine Fe3O4 and CeO2, showing highest rate constant value of 18.2 x 10-3 min-1 for the ternary nanocomposite.	ferryl iron	106-111	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
31308407-10	2019	The kinetics investigations revealed 2.55 and 4.04 times increased rate of reactions compared to pristine Fe3O4 and CeO2, showing highest rate constant value of 18.2 x 10-3 min-1 for the ternary nanocomposite.	ceric oxide	116-120	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
31299992-13	2019	The best available estimate of the flow velocity is thus 0.25 microm min-1 which is 200 times smaller than the flow that produces effects comparable to diffusion for TMA+.	4,4-dimethylcholesta-8,14-dien-3-ol	166-170	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
31406654-1	2019	P450 119 peroxygenase was found to catalyze the sulfoxidation of thioanisole and the sulfonation of sulfoxide in the presence of tert-butyl hydroperoxide (TBHP) for the first time with turnover rates of 1549 min-1 and 196 min-1 respectively.	methylphenylsulfide	65-76	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
31417756-2	2019	In this work, muscovite single crystal was irradiated with Co-60 gamma ray in air at a dose rate of 54 Gy min-1 with doses of 0-1000 kGy.	muscovite	14-23	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
31406654-1	2019	P450 119 peroxygenase was found to catalyze the sulfoxidation of thioanisole and the sulfonation of sulfoxide in the presence of tert-butyl hydroperoxide (TBHP) for the first time with turnover rates of 1549 min-1 and 196 min-1 respectively.	methylphenylsulfide	65-76	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
31406654-1	2019	P450 119 peroxygenase was found to catalyze the sulfoxidation of thioanisole and the sulfonation of sulfoxide in the presence of tert-butyl hydroperoxide (TBHP) for the first time with turnover rates of 1549 min-1 and 196 min-1 respectively.	sulfoxide	100-109	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
31406654-1	2019	P450 119 peroxygenase was found to catalyze the sulfoxidation of thioanisole and the sulfonation of sulfoxide in the presence of tert-butyl hydroperoxide (TBHP) for the first time with turnover rates of 1549 min-1 and 196 min-1 respectively.	sulfoxide	100-109	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
31406654-1	2019	P450 119 peroxygenase was found to catalyze the sulfoxidation of thioanisole and the sulfonation of sulfoxide in the presence of tert-butyl hydroperoxide (TBHP) for the first time with turnover rates of 1549 min-1 and 196 min-1 respectively.	tert-Butylhydroperoxide	129-153	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
31406654-1	2019	P450 119 peroxygenase was found to catalyze the sulfoxidation of thioanisole and the sulfonation of sulfoxide in the presence of tert-butyl hydroperoxide (TBHP) for the first time with turnover rates of 1549 min-1 and 196 min-1 respectively.	tert-Butylhydroperoxide	129-153	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
31406654-1	2019	P450 119 peroxygenase was found to catalyze the sulfoxidation of thioanisole and the sulfonation of sulfoxide in the presence of tert-butyl hydroperoxide (TBHP) for the first time with turnover rates of 1549 min-1 and 196 min-1 respectively.	tert-Butylhydroperoxide	155-159	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
31406654-1	2019	P450 119 peroxygenase was found to catalyze the sulfoxidation of thioanisole and the sulfonation of sulfoxide in the presence of tert-butyl hydroperoxide (TBHP) for the first time with turnover rates of 1549 min-1 and 196 min-1 respectively.	tert-Butylhydroperoxide	155-159	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
31406654-6	2019	Octanoic acid was found to induce a preferred sulfoxidation of thioanisole catalyzed by the F153G/T213G mutant to give approximately 2.4-fold increase in turnover rate with a k cat value of 3687 min-1 relative to that of the wild-type, and by the F153G mutant to give the R-sulfoxide up to 30 % ee.	octanoic acid	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	195-200
31406654-6	2019	Octanoic acid was found to induce a preferred sulfoxidation of thioanisole catalyzed by the F153G/T213G mutant to give approximately 2.4-fold increase in turnover rate with a k cat value of 3687 min-1 relative to that of the wild-type, and by the F153G mutant to give the R-sulfoxide up to 30 % ee.	methylphenylsulfide	63-74	CD59 molecule (CD59 blood group)	Homo sapiens	195-200
31406654-6	2019	Octanoic acid was found to induce a preferred sulfoxidation of thioanisole catalyzed by the F153G/T213G mutant to give approximately 2.4-fold increase in turnover rate with a k cat value of 3687 min-1 relative to that of the wild-type, and by the F153G mutant to give the R-sulfoxide up to 30 % ee.	r-sulfoxide	272-283	CD59 molecule (CD59 blood group)	Homo sapiens	195-200
30981734-3	2019	In this study, we investigated the expression and possible function of CD59, one of the membrane-bound complement regulators, in EVTs.	evts	129-133	CD59 molecule (CD59 blood group)	Homo sapiens	71-75
31032889-11	2019	We found some correlation (R2  = 0.85) between overall fresh gas flow and vapour consumption; a 1 l.min-1 increase in fresh gas flow consumes an additional 18 ml.hr-1 of liquid sevoflurane.	Sevoflurane	177-188	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
30734168-0	2019	Association of serum uric acid levels with the incident of kidney disease and rapid eGFR decline in Chinese individuals with eGFR &gt; 60 mL/min/1.73 m2 and negative proteinuria.	Uric Acid	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
31082363-9	2019	Herein, the evidence for the role of MAC in the pathophysiology of dry as well as wet AMD and the scientific rationale underlying the use of AAV- delivered CD59 for the treatment of dry and wet AMD is discussed.	CHEMBL2031461	141-144	CD59 molecule (CD59 blood group)	Homo sapiens	156-160
30964977-5	2019	Interestingly, both CYP1B1.1 and 1B1.3 converted 57diOHF to 567triOHF at turnover rates (on the basis of P450 contents) of &gt;3.0 min-1, and CYP1A1 and 1A2 produced 567triOHF at rates of 0.51 and 0.72 min-1, respectively.	57diohf	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
30964977-5	2019	Interestingly, both CYP1B1.1 and 1B1.3 converted 57diOHF to 567triOHF at turnover rates (on the basis of P450 contents) of &gt;3.0 min-1, and CYP1A1 and 1A2 produced 567triOHF at rates of 0.51 and 0.72 min-1, respectively.	57diohf	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	202-207
30927596-5	2019	Rh0, Ru0 and Pd0 nanoparticles on activated carbon provide a turnover frequency value of 188 min-1, 235 min-1 and 40 min-1, respectively, at 25.0 +- 0.1  C. They preserve their activity even after multiple use in H2 generation from the hydrolysis of ammonia borane.	Carbon	44-50	CD59 molecule (CD59 blood group)	Homo sapiens	104-122
30927596-5	2019	Rh0, Ru0 and Pd0 nanoparticles on activated carbon provide a turnover frequency value of 188 min-1, 235 min-1 and 40 min-1, respectively, at 25.0 +- 0.1  C. They preserve their activity even after multiple use in H2 generation from the hydrolysis of ammonia borane.	Hydrogen	213-215	CD59 molecule (CD59 blood group)	Homo sapiens	104-122
30927596-5	2019	Rh0, Ru0 and Pd0 nanoparticles on activated carbon provide a turnover frequency value of 188 min-1, 235 min-1 and 40 min-1, respectively, at 25.0 +- 0.1  C. They preserve their activity even after multiple use in H2 generation from the hydrolysis of ammonia borane.	Ammonia borane	250-264	CD59 molecule (CD59 blood group)	Homo sapiens	104-122
31256175-10	2019	Cutoff of &gt;=0.68mumol/L, ADMA levels predict reduction of eGFR&lt;60 mL/min/1.73m2, sensitivity of 86.9 %, specificity of 82.6%, area under ROC 92.4% (95%CI: 88.6-96.1%).	N,N-dimethylarginine	28-32	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
30972400-12	2019	The observed apparent rate constant for the photocatalytic MB degradation using 10 mol% Ag-ZnO (Kapp = 6.01 x 10-2 min-1) was six times that of pure ZnO (Kapp = 1.09 x 10-2 min-1).	ag-zno	88-94	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
30972400-12	2019	The observed apparent rate constant for the photocatalytic MB degradation using 10 mol% Ag-ZnO (Kapp = 6.01 x 10-2 min-1) was six times that of pure ZnO (Kapp = 1.09 x 10-2 min-1).	ag-zno	88-94	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
30972400-12	2019	The observed apparent rate constant for the photocatalytic MB degradation using 10 mol% Ag-ZnO (Kapp = 6.01 x 10-2 min-1) was six times that of pure ZnO (Kapp = 1.09 x 10-2 min-1).	Zinc Oxide	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
30972400-12	2019	The observed apparent rate constant for the photocatalytic MB degradation using 10 mol% Ag-ZnO (Kapp = 6.01 x 10-2 min-1) was six times that of pure ZnO (Kapp = 1.09 x 10-2 min-1).	Zinc Oxide	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
30793280-9	2019	Repeating this last study at a flow rate of 2 ml.min-1 resulted in quite high aluminium concentrations when the uncoated device was not heated (~1000 mug.l-1 ) and higher concentrations after the device was heated.	Aluminum	78-87	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
31273172-9	2019	Patients with an estimated glomerular filtration rate of less than 50mL/min/1.73m2 received a lower cumulative dose of ixazomib and lenalidomide than those with other rates.	ixazomib	119-127	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
31273172-9	2019	Patients with an estimated glomerular filtration rate of less than 50mL/min/1.73m2 received a lower cumulative dose of ixazomib and lenalidomide than those with other rates.	Lenalidomide	132-144	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
31207657-10	2019	We found a statistically significant (p=0.027) relationship between the duration of calcitriol treatment and renal function decline at a rate of 1.06 ml/min/1.73 m2 per year of calcitriol therapy.	Calcitriol	84-94	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
31207657-10	2019	We found a statistically significant (p=0.027) relationship between the duration of calcitriol treatment and renal function decline at a rate of 1.06 ml/min/1.73 m2 per year of calcitriol therapy.	Calcitriol	177-187	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
31318346-8	2019	The removal efficiency of quinoline reached more than 97% for a velocity of 6 mL min-1 at the initial adsorption stage.	quinoline	26-35	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
31193778-4	2019	Resveratrol at concentrations as low as 0.001 muMu increased HO-1 expression as well as membrane cofactor protein (MCP, CD46) and decay-accelerating factor (DAF, CD55) expression with no-effect on CD59.	Resveratrol	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	197-201
30743169-4	2019	As a result, a satisfactory separation of penconazole enantiomers on a chiral Lux Cellulose-2 column (150 mm x 2 mm i.d., 3 microm) was obtained with 0.1% formic acid in methanol and 10 mmol L-1 ammonium acetate in water (75/25, v/v) as mobile phase at 0.25 mL min-1.	penconazole	42-53	CD59 molecule (CD59 blood group)	Homo sapiens	261-266
30737351-8	2019	DndCDE with an intact iron-sulfur cluster (DndCDE-FeS) possessed H2O2 decomposition activity, with a V max of 10.58 +- 0.90 mM min-1 and a half-saturation constant, K 0.5S, of 31.03 mM.	dndcde	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
30338662-6	2019	The hydrogen production rate in a large PEM-PEC cell (16 cm2 ) was 10 mumol min-1 .	Hydrogen	4-12	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
30826558-3	2019	Experimental results indicate that optimum removal rate of MDEA can be obtained at pH = 2, inlet air rate = 1 L min-1, mass ratio of filings to wastewater = 1:1 and temperature = 25  C. About 96.0% Total Organic Carbon (TOC) in overhaul wastewater can be mineralized by ozonation-microelectrolysis-ozonation (OMIO) treatment process.	N-methyldiethanolamine	59-63	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
30813746-7	2019	RESULTS: Plasma asymmetric dimethylarginine concentrations were increased ( P &lt; 0.01) in people with glomerular filtration rate &lt;60 mL/min/1.73 m2 compared with those with glomerular filtration rate &gt;=60 mL/min/1.73 m2, but did not differ ( P &gt; 0.05) between those with glomerular filtration rate 30-59 mL/min/1.73 m2 and &lt;30 mL/min/1.73 m2.	dimethylarginine	27-43	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
30813746-7	2019	RESULTS: Plasma asymmetric dimethylarginine concentrations were increased ( P &lt; 0.01) in people with glomerular filtration rate &lt;60 mL/min/1.73 m2 compared with those with glomerular filtration rate &gt;=60 mL/min/1.73 m2, but did not differ ( P &gt; 0.05) between those with glomerular filtration rate 30-59 mL/min/1.73 m2 and &lt;30 mL/min/1.73 m2.	dimethylarginine	27-43	CD59 molecule (CD59 blood group)	Homo sapiens	216-221
30813746-7	2019	RESULTS: Plasma asymmetric dimethylarginine concentrations were increased ( P &lt; 0.01) in people with glomerular filtration rate &lt;60 mL/min/1.73 m2 compared with those with glomerular filtration rate &gt;=60 mL/min/1.73 m2, but did not differ ( P &gt; 0.05) between those with glomerular filtration rate 30-59 mL/min/1.73 m2 and &lt;30 mL/min/1.73 m2.	dimethylarginine	27-43	CD59 molecule (CD59 blood group)	Homo sapiens	216-221
30813746-7	2019	RESULTS: Plasma asymmetric dimethylarginine concentrations were increased ( P &lt; 0.01) in people with glomerular filtration rate &lt;60 mL/min/1.73 m2 compared with those with glomerular filtration rate &gt;=60 mL/min/1.73 m2, but did not differ ( P &gt; 0.05) between those with glomerular filtration rate 30-59 mL/min/1.73 m2 and &lt;30 mL/min/1.73 m2.	dimethylarginine	27-43	CD59 molecule (CD59 blood group)	Homo sapiens	216-221
30820661-5	2019	The rate of oxygen desaturation during the first 3 min of exercise was accelerated in severe hypoxia (- 5.3 +- 2.8% min- 1) relative to moderate hypoxia (- 2.5 +- 1.0% min- 1) and normoxia (- 0.7 +- 0.3% min- 1).	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
30820661-5	2019	The rate of oxygen desaturation during the first 3 min of exercise was accelerated in severe hypoxia (- 5.3 +- 2.8% min- 1) relative to moderate hypoxia (- 2.5 +- 1.0% min- 1) and normoxia (- 0.7 +- 0.3% min- 1).	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
30820661-5	2019	The rate of oxygen desaturation during the first 3 min of exercise was accelerated in severe hypoxia (- 5.3 +- 2.8% min- 1) relative to moderate hypoxia (- 2.5 +- 1.0% min- 1) and normoxia (- 0.7 +- 0.3% min- 1).	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
30776180-9	2019	The addition of naringenin significantly and dose-dependently increased the respiratory rate from 5.8 +- 0.2 to 14.0 +- 0.6 nmol O2  x min-1  x mg protein-1 .	naringenin	16-26	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
30776180-9	2019	The addition of naringenin significantly and dose-dependently increased the respiratory rate from 5.8 +- 0.2 to 14.0 +- 0.6 nmol O2  x min-1  x mg protein-1 .	Oxygen	129-131	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
30726978-4	2019	The measured incident energy of the alpha-particles was 3.3 +- 0.5 MeV (LET in water = 120 keV mum-1), with a maximum incident dose rate of 1.28 +- 0.02 Gy min-1, which for a 5 mum cell monolayer corresponds to a mean dose rate of 1.57 +- 0.02 Gy min-1 and a mean LET in water of 154 keV mum-1.	Water	271-276	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
31013654-5	2019	According to the experimental results, the formation process of carbonate minerals under cold seep conditions was estimated, that 1 m carbonate growth needs 12,000 and 7000 years, respectively, under fast (5 mL min-1) and slow emission (1 mL min-1) conditions.	Carbonates	64-73	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
31013654-5	2019	According to the experimental results, the formation process of carbonate minerals under cold seep conditions was estimated, that 1 m carbonate growth needs 12,000 and 7000 years, respectively, under fast (5 mL min-1) and slow emission (1 mL min-1) conditions.	Carbonates	64-73	CD59 molecule (CD59 blood group)	Homo sapiens	242-247
31003568-6	2019	For the sample A1M1 calcined and completely rehydrated (Ca(OH)2), the chemical adsorption of CO2 to form CaCO3 is practically total, under the experimental conditions used (550  C and CO2 flow of 20 mL min-1).	Calcium Hydroxide	56-63	CD59 molecule (CD59 blood group)	Homo sapiens	202-207
31003568-6	2019	For the sample A1M1 calcined and completely rehydrated (Ca(OH)2), the chemical adsorption of CO2 to form CaCO3 is practically total, under the experimental conditions used (550  C and CO2 flow of 20 mL min-1).	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	93-96	CD59 molecule (CD59 blood group)	Homo sapiens	202-207
30737351-8	2019	DndCDE with an intact iron-sulfur cluster (DndCDE-FeS) possessed H2O2 decomposition activity, with a V max of 10.58 +- 0.90 mM min-1 and a half-saturation constant, K 0.5S, of 31.03 mM.	Sulfur	27-33	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
30737351-8	2019	DndCDE with an intact iron-sulfur cluster (DndCDE-FeS) possessed H2O2 decomposition activity, with a V max of 10.58 +- 0.90 mM min-1 and a half-saturation constant, K 0.5S, of 31.03 mM.	dndcde	43-49	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
30737351-8	2019	DndCDE with an intact iron-sulfur cluster (DndCDE-FeS) possessed H2O2 decomposition activity, with a V max of 10.58 +- 0.90 mM min-1 and a half-saturation constant, K 0.5S, of 31.03 mM.	Iron	50-53	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
30697837-7	2019	Due to the photoformed valence band holes and selective two-electron reduction of O2 by the conduction band electrons, it also renders an efficient, economic, and green route to light-driven H2 O2 production with an initial rate of 0.75 x 10-6 m min-1 .	Oxygen	82-84	CD59 molecule (CD59 blood group)	Homo sapiens	246-251
30697837-7	2019	Due to the photoformed valence band holes and selective two-electron reduction of O2 by the conduction band electrons, it also renders an efficient, economic, and green route to light-driven H2 O2 production with an initial rate of 0.75 x 10-6 m min-1 .	Hydrogen Peroxide	191-196	CD59 molecule (CD59 blood group)	Homo sapiens	246-251
30767199-7	2019	With no cardiogenic oscillations applied, mean (SD) carbon dioxide clearance increased from 0.29 (0.04) ml.min-1 to 1.34 (0.14) ml.min-1 as the transnasal humidified rapid-insufflation ventilatory exchange flow rate was increased from 20 l.min-1 to 70 l.min-1 (p = 0.0001).	Carbon Dioxide	52-66	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
30767199-7	2019	With no cardiogenic oscillations applied, mean (SD) carbon dioxide clearance increased from 0.29 (0.04) ml.min-1 to 1.34 (0.14) ml.min-1 as the transnasal humidified rapid-insufflation ventilatory exchange flow rate was increased from 20 l.min-1 to 70 l.min-1 (p = 0.0001).	Carbon Dioxide	52-66	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
30767199-7	2019	With no cardiogenic oscillations applied, mean (SD) carbon dioxide clearance increased from 0.29 (0.04) ml.min-1 to 1.34 (0.14) ml.min-1 as the transnasal humidified rapid-insufflation ventilatory exchange flow rate was increased from 20 l.min-1 to 70 l.min-1 (p = 0.0001).	Carbon Dioxide	52-66	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
30767199-7	2019	With no cardiogenic oscillations applied, mean (SD) carbon dioxide clearance increased from 0.29 (0.04) ml.min-1 to 1.34 (0.14) ml.min-1 as the transnasal humidified rapid-insufflation ventilatory exchange flow rate was increased from 20 l.min-1 to 70 l.min-1 (p = 0.0001).	Carbon Dioxide	52-66	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
30767199-8	2019	With a cardiogenic oscillation of 20 ml.beat-1 applied, carbon dioxide clearance increased from 11.9 (0.50) ml.min-1 to 17.4 (1.2) ml.min-1 as the transnasal humidified rapid-insufflation ventilatory exchange flow rate was increased from 20 l.min-1 to 70 l.min-1 (p = 0.0014).	Carbon Dioxide	56-70	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
30767199-8	2019	With a cardiogenic oscillation of 20 ml.beat-1 applied, carbon dioxide clearance increased from 11.9 (0.50) ml.min-1 to 17.4 (1.2) ml.min-1 as the transnasal humidified rapid-insufflation ventilatory exchange flow rate was increased from 20 l.min-1 to 70 l.min-1 (p = 0.0014).	Carbon Dioxide	56-70	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
30767199-8	2019	With a cardiogenic oscillation of 20 ml.beat-1 applied, carbon dioxide clearance increased from 11.9 (0.50) ml.min-1 to 17.4 (1.2) ml.min-1 as the transnasal humidified rapid-insufflation ventilatory exchange flow rate was increased from 20 l.min-1 to 70 l.min-1 (p = 0.0014).	Carbon Dioxide	56-70	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
30767199-8	2019	With a cardiogenic oscillation of 20 ml.beat-1 applied, carbon dioxide clearance increased from 11.9 (0.50) ml.min-1 to 17.4 (1.2) ml.min-1 as the transnasal humidified rapid-insufflation ventilatory exchange flow rate was increased from 20 l.min-1 to 70 l.min-1 (p = 0.0014).	Carbon Dioxide	56-70	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
31939221-3	2019	Thanks to the strong electronic interaction between Ni, Co, and P, the as-synthesized Co89.8 Ni10.2 P11.7 /rGO catalyst exhibits superior catalytic performance towards hydrolysis of AB, with the turnover frequency value (TOF) of 18.6 min-1 , which is about 2.5 times higher than that of NiCo/rGO.	12-(4'-azido-2'-nitrophenoxy)dodecanoyl-coenzyme A	86-88	CD59 molecule (CD59 blood group)	Homo sapiens	234-239
31939221-3	2019	Thanks to the strong electronic interaction between Ni, Co, and P, the as-synthesized Co89.8 Ni10.2 P11.7 /rGO catalyst exhibits superior catalytic performance towards hydrolysis of AB, with the turnover frequency value (TOF) of 18.6 min-1 , which is about 2.5 times higher than that of NiCo/rGO.	Ammonia	182-184	CD59 molecule (CD59 blood group)	Homo sapiens	234-239
30820921-2	2019	The presence of 25 mg/L 10Pd/C significantly increased the removal rate of butylparaben and the observed kinetic constant increased from 0.0126 to 0.071 min-1, while the synergy index between sonolysis and adsorption was 70.7%.	butylparaben	75-87	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
30820921-3	2019	The BP degradation followed pseudo-first-order kinetics with the apparent kinetic constant decreased from 0.071 to 0.030 min-1 when the initial concentration of butylparaben increased from 0.5 to 2 mg/L.	butylparaben	161-173	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
30820921-6	2019	The addition of chlorides up to 250 mg/L did not significantly reduce the rate of reaction, while the presence of 250 mg/L bicarbonates reduced the observed kinetic constant from 0.071 to 0.0472 min-1.	Bicarbonates	123-135	CD59 molecule (CD59 blood group)	Homo sapiens	195-200
31303142-10	2019	The creatinine-based estimated glomerular filtration rate decreased by a mean of -8.4 ml/min/1.73 m2, but tubular renal parameters improved.	Creatinine	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
31531080-6	2019	Compared with children with normal renal function as glomerular filtration rate (GFR) &gt;= 90 mL/min 1.73 m2, the clearance of vancomycin decreased by 39.4% and the half life increased 1.74 fold respectively in children with moderate renal inadequacy (30 &lt;= GFR &lt; 60 mL/min 1.73 m2).	Vancomycin	128-138	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
31531080-6	2019	Compared with children with normal renal function as glomerular filtration rate (GFR) &gt;= 90 mL/min 1.73 m2, the clearance of vancomycin decreased by 39.4% and the half life increased 1.74 fold respectively in children with moderate renal inadequacy (30 &lt;= GFR &lt; 60 mL/min 1.73 m2).	Vancomycin	128-138	CD59 molecule (CD59 blood group)	Homo sapiens	277-282
30328093-9	2019	After multivariable adjustment, a 1 mmol/L increase in baseline serum sodium was associated with a 1.5 mL/min/1.73 m2 decline in eGFR during the study period (95% CI 0.9, 2.0).	Sodium	70-76	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
31090293-7	2019	The optimum formulation of volatile oil liposome was as follows: the concentration of lecithin was 7 g L~(-1); mass ratio of lecithin to volatile oil was 5:1; and the stirring speed was 330 r min~(-1).	Oils, Volatile	27-39	CD59 molecule (CD59 blood group)	Homo sapiens	192-199
30874713-8	2019	We observed a high removal capacity of 129 mg g-1 at the low energy consumption of 0.4 W h g-1 for a salt concentration of ~3000 mg L-1 at 50 ml min-1 flow rate.	Salts	101-105	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
30901878-6	2019	For the range of [PA]0 covered under air saturated conditions and 30 mL min-1 flow of air in this setup, the estimated half-lives of O2(aq) consumed by the photolytic radicalsfall within the interval from 22 to 3 min.	Oxygen	133-135	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
30901878-6	2019	For the range of [PA]0 covered under air saturated conditions and 30 mL min-1 flow of air in this setup, the estimated half-lives of O2(aq) consumed by the photolytic radicalsfall within the interval from 22 to 3 min.	aq	136-138	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
30949065-5	2019	Mean power output for the duration of the simulated race (91.63 +- 7.19 s) was 203.8 +- 45.0 W, incurring an oxygen deficit of 1.386 +- 0.541 L min-1 translating to an overall anaerobic contribution of 32 +- 18% and aerobic contribution of 68 +- 18%.	Oxygen	109-115	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
30949471-4	2019	Ni-Zn/SiO2 showed a high catalytic activity when water was used as a solvent, where the reaction was completed within 6 min at room temperature with a specific reaction rate of 4.3 ml min-1 mmol-cat-1 mM-AB-1.	ni-zn	0-5	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
30949471-4	2019	Ni-Zn/SiO2 showed a high catalytic activity when water was used as a solvent, where the reaction was completed within 6 min at room temperature with a specific reaction rate of 4.3 ml min-1 mmol-cat-1 mM-AB-1.	Silicon Dioxide	6-10	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
30949471-4	2019	Ni-Zn/SiO2 showed a high catalytic activity when water was used as a solvent, where the reaction was completed within 6 min at room temperature with a specific reaction rate of 4.3 ml min-1 mmol-cat-1 mM-AB-1.	Water	49-54	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
30834901-4	2019	At 900  C, oxygen fluxes of 1.01 mL min-1 cm-2 and 1.33 mL min-1 cm-2 were obtained for membranes with thicknesses of 1.35 mm and 0.75 mm, respectively.	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	36-52
30834901-4	2019	At 900  C, oxygen fluxes of 1.01 mL min-1 cm-2 and 1.33 mL min-1 cm-2 were obtained for membranes with thicknesses of 1.35 mm and 0.75 mm, respectively.	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
30777440-5	2019	By adjusting the content of Ni and Ni2P in the hetrostructure, the optimized hybrid exhibits catalytic performance of H2 generation from the hydrolysis of AB under ambient conditions with a turnover frequency of 68.3 mol (H2) mol-1 (Cat) min-1 and an activation energy ( Ea) of 44.99 kJ mol-1, implying its high potential as an efficient supplement for noble-metal-based catalysts in hydrogen energy applications.	ni2p	35-39	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
30777440-5	2019	By adjusting the content of Ni and Ni2P in the hetrostructure, the optimized hybrid exhibits catalytic performance of H2 generation from the hydrolysis of AB under ambient conditions with a turnover frequency of 68.3 mol (H2) mol-1 (Cat) min-1 and an activation energy ( Ea) of 44.99 kJ mol-1, implying its high potential as an efficient supplement for noble-metal-based catalysts in hydrogen energy applications.	Hydrogen	118-120	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
30777440-5	2019	By adjusting the content of Ni and Ni2P in the hetrostructure, the optimized hybrid exhibits catalytic performance of H2 generation from the hydrolysis of AB under ambient conditions with a turnover frequency of 68.3 mol (H2) mol-1 (Cat) min-1 and an activation energy ( Ea) of 44.99 kJ mol-1, implying its high potential as an efficient supplement for noble-metal-based catalysts in hydrogen energy applications.	Metals	359-364	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
30777440-5	2019	By adjusting the content of Ni and Ni2P in the hetrostructure, the optimized hybrid exhibits catalytic performance of H2 generation from the hydrolysis of AB under ambient conditions with a turnover frequency of 68.3 mol (H2) mol-1 (Cat) min-1 and an activation energy ( Ea) of 44.99 kJ mol-1, implying its high potential as an efficient supplement for noble-metal-based catalysts in hydrogen energy applications.	Hydrogen	384-392	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
31057747-3	2019	Herein, we describe the thermosalient effect of the triphenylethenyl gold 4-chlorophenyl isocyanide complex 1, which jumps reversibly at approximately -100  C upon cooling at 50  C min-1 and heating at 30  C min-1.	triphenylethenyl gold 4-chlorophenyl isocyanide complex	52-107	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
31057747-3	2019	Herein, we describe the thermosalient effect of the triphenylethenyl gold 4-chlorophenyl isocyanide complex 1, which jumps reversibly at approximately -100  C upon cooling at 50  C min-1 and heating at 30  C min-1.	triphenylethenyl gold 4-chlorophenyl isocyanide complex	52-107	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
30291473-6	2019	The eGFR in the febuxostat group showed an increase from 28.45 to 30.65 mL/min/1.73 m2 at 6 months, while in the allopurinol group, the eGFR decreased from 28.06 to 24.39 mL/min/1.73 m2.	Febuxostat	16-26	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
30291473-6	2019	The eGFR in the febuxostat group showed an increase from 28.45 to 30.65 mL/min/1.73 m2 at 6 months, while in the allopurinol group, the eGFR decreased from 28.06 to 24.39 mL/min/1.73 m2.	Febuxostat	16-26	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
30607464-9	2019	LBF and vascular conductance were lower during ATP (0.15 and 0.4 mumol min-1 [kg leg mass]-1) and ACh (100 mug min-1 [kg leg mass]-1) infusion in individuals with type 2 diabetes compared with the control participants (p &lt; 0.05), whereas there was no difference during SNP infusion.	Adenosine Triphosphate	47-50	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
30607464-9	2019	LBF and vascular conductance were lower during ATP (0.15 and 0.4 mumol min-1 [kg leg mass]-1) and ACh (100 mug min-1 [kg leg mass]-1) infusion in individuals with type 2 diabetes compared with the control participants (p &lt; 0.05), whereas there was no difference during SNP infusion.	Acetylcholine	98-101	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
30506579-16	2019	Finally, in a subset of six subjects, direct pharmacological activation of KIR channels in quiescent muscle via infusion of KCl amplified peak ACh-mediated vasodilatation (DeltaFVC saline: 97 +- 15, KCl: 142 +- 16 ml min-1  (100 mmHg)-1 ; respectively; P &lt; 0.05).	Potassium Chloride	124-127	CD59 molecule (CD59 blood group)	Homo sapiens	217-236
30882670-6	2019	In subgroup analysis, major bleeding was significantly increased in the subgroup of creatinine clearance &lt;60 ml/min/1.73 m, hypertension, underwent a trans-femoral approach and diagnosed as NSTEMI among the prasugrel/ticagrelor group.The use of prasugrel/ticagrelor did not improve the composite of CD, recurrent MI or stroke, however, significantly increased major bleeding events in Korean patients with MI and diabetes undergoing PCI.	Prasugrel Hydrochloride	210-219	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
31086503-8	2019	Excluding dialysis patients, Creatinine clearance was 21.1+-6.6ml/min/1.73m2.	Creatinine	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
30741302-4	2019	An optimum AB hydrolysis rate was obtained when the size of the Ni NPs was 3.2 nm, with an initial turnover frequency of 18.7 mol(hydrogen) mol(catalyst)-1 min-1 and an apparent activation energy of 36 kJ mol-1.	Hydrogen	130-138	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
30949530-8	2019	Bivariate analysis identified only baseline creatinine clearance &gt;80 mL min-1 (Cockcroft-Gault) as a possible predictor of SVR12 failure (P = .026).	Creatinine	44-54	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
30949530-9	2019	In the multivariate analysis, pretreatment creatinine clearance &gt;80 mL min-1 remained independently associated with SVR12 failure (odds ratio, 2.95; 95% confidence interval, 1.17-7.46; P = .023).	Creatinine	43-53	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
30949530-10	2019	Conclusions: In hepatitis C patients treated with LDV/SOF, a pretreatment creatinine clearance of &gt;80 mL min-1 was associated with SVR12 failure.	Creatinine	74-84	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
30736366-4	2019	In this multicenter, single-arm, open-label, phase III trial, 0.2-0.4 mg/day pemafibrate was administered for 52 weeks to 189 patients with hypertriglyceridemia and an estimated glomerular filtration rate (eGFR) &gt;= 45 mL/min/1.73 m2 on statin or regardless of eGFR when statin was not administered.	(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid	77-88	CD59 molecule (CD59 blood group)	Homo sapiens	224-229
30989031-7	2019	For the reduction of 4-nitrophenol, the reaction rate constant K app is 0.23 min-1 and the turnover frequency (TOF) is up to 3062 h-1.	4-nitrophenol	21-34	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
30702553-10	2019	INTERVENTIONS AND OUTCOMES: Bortezomib and dexamethasone were started and her renal function improved to eGFR 36 mL/min/1.73 m after 9 courses of therapy.	Bortezomib	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
30590241-5	2019	The coating also catalytically decomposed endogenous S-nitrosothiols (RSNOs) from fresh blood, and locally generated NO for over 30 days with a flux comparable to its physiological range (0.5-4 x 10-10 mol x cm-2 x min-1).	rsnos	70-75	CD59 molecule (CD59 blood group)	Homo sapiens	215-220
30360203-5	2019	MgAC[0.7 g]-Fe3O4 nanocomposite exhibited the best photo-Fenton catalysis with methylene blue (MB) was completely removed from the treatment solution at a constant rate of 0.0083 (min-1) on the batch scale.	mgac	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
30360203-5	2019	MgAC[0.7 g]-Fe3O4 nanocomposite exhibited the best photo-Fenton catalysis with methylene blue (MB) was completely removed from the treatment solution at a constant rate of 0.0083 (min-1) on the batch scale.	ferryl iron	12-17	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
30360203-5	2019	MgAC[0.7 g]-Fe3O4 nanocomposite exhibited the best photo-Fenton catalysis with methylene blue (MB) was completely removed from the treatment solution at a constant rate of 0.0083 (min-1) on the batch scale.	Methylene Blue	79-93	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
30360203-5	2019	MgAC[0.7 g]-Fe3O4 nanocomposite exhibited the best photo-Fenton catalysis with methylene blue (MB) was completely removed from the treatment solution at a constant rate of 0.0083 (min-1) on the batch scale.	Methylene Blue	95-97	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
30702553-10	2019	INTERVENTIONS AND OUTCOMES: Bortezomib and dexamethasone were started and her renal function improved to eGFR 36 mL/min/1.73 m after 9 courses of therapy.	Dexamethasone	43-56	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
30586310-1	2019	The first total synthesis of a lipid mediator derived from natural omega-3-fatty acid docosahexaenoic acid (DHA), 10 S,17 S-diHDHA (also referred to as protectin DX/PDX), was achieved in a convergent route (29 steps).	Fatty Acids, Omega-3	67-85	CD59 molecule (CD59 blood group)	Homo sapiens	152-161
30341979-8	2019	Validation results for the Omnical with methanol combustion were -0.05 +- 0.70% (mean +- SD; n = 31) at the 225 mL min-1 VO2 level and -0.23 +- 0.80% (n = 31) at the 150 mL min-1 VCO2 level.	Methanol	40-48	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
30341979-8	2019	Validation results for the Omnical with methanol combustion were -0.05 +- 0.70% (mean +- SD; n = 31) at the 225 mL min-1 VO2 level and -0.23 +- 0.80% (n = 31) at the 150 mL min-1 VCO2 level.	Methanol	40-48	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
30607962-5	2019	The optimized catalysts obtained via calcination at 800  C show a set of remarkable catalytic benefits, including a high hydrogen generation rate of 8.4 mol min-1 mol(Co)-1, a relatively low activation energy of 36.1 kJ mol-1, and a remarkable reusability (at least 10 times).	Hydrogen	121-129	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
30586310-1	2019	The first total synthesis of a lipid mediator derived from natural omega-3-fatty acid docosahexaenoic acid (DHA), 10 S,17 S-diHDHA (also referred to as protectin DX/PDX), was achieved in a convergent route (29 steps).	Docosahexaenoic Acids	86-106	CD59 molecule (CD59 blood group)	Homo sapiens	152-161
30586310-1	2019	The first total synthesis of a lipid mediator derived from natural omega-3-fatty acid docosahexaenoic acid (DHA), 10 S,17 S-diHDHA (also referred to as protectin DX/PDX), was achieved in a convergent route (29 steps).	Docosahexaenoic Acids	108-111	CD59 molecule (CD59 blood group)	Homo sapiens	152-161
30586310-1	2019	The first total synthesis of a lipid mediator derived from natural omega-3-fatty acid docosahexaenoic acid (DHA), 10 S,17 S-diHDHA (also referred to as protectin DX/PDX), was achieved in a convergent route (29 steps).	s-dihdha	122-130	CD59 molecule (CD59 blood group)	Homo sapiens	152-161
30586310-1	2019	The first total synthesis of a lipid mediator derived from natural omega-3-fatty acid docosahexaenoic acid (DHA), 10 S,17 S-diHDHA (also referred to as protectin DX/PDX), was achieved in a convergent route (29 steps).	10-propargyl-10-deazaaminopterin	165-168	CD59 molecule (CD59 blood group)	Homo sapiens	152-161
30402894-6	2019	Results showed that the uptake kinetic parameters Vmax and Km for SAB in HepG2 cells were 21.28 +- 2.06 pmol mg-1 per protein min-1 and 28.47 +- 7.36 muM, respectively.	salvianolic acid B	66-69	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
31032394-5	2019	ADE levels of inhibitory CPs decay-accelerating factor, CD46, CD59, and type 1 complement receptor were significantly lower in patients with MCIC than those with MCIS.	Adenine	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	62-66
30625200-5	2019	We focused on oxygen uptake standards and compared the maximal oxygen uptake [mLO2 kg-1 min-1] values with those in the existing literature.	Oxygen	63-69	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
30625200-11	2019	In our cohort, the 50th percentile maximal oxygen uptake values for men and women decreased from 44.7 and 36.3 mLO2 kg-1 min-1 to 28.4 and 22.3 mLO2 kg-1 min-1 for patients aged 20-29 years to patients aged 60-69 years, respectively.	Oxygen	43-49	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
30625200-11	2019	In our cohort, the 50th percentile maximal oxygen uptake values for men and women decreased from 44.7 and 36.3 mLO2 kg-1 min-1 to 28.4 and 22.3 mLO2 kg-1 min-1 for patients aged 20-29 years to patients aged 60-69 years, respectively.	Oxygen	43-49	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
32254959-8	2019	Among these blend films, PU-Se-10 exhibited a stable NO release rate of 5.05 x 10-10 mol cm-2 min-1 after exposure to PBS buffer for 30 days.	pu-se-10	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
32254959-8	2019	Among these blend films, PU-Se-10 exhibited a stable NO release rate of 5.05 x 10-10 mol cm-2 min-1 after exposure to PBS buffer for 30 days.	Lead	118-121	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
30284536-6	2019	The optimized TPU nanofibers based air filters demonstrate the attractive attributes of high PM2.5 removal efficiency up to 98.92%, good optical transparency of ~60%, low pressure drop of ~10 Pa, high quality factor of 0.45 Pa-1, and long service life under the flow rate of 200 ml min-1, which is ground-breaking compared with the existing nanofibers based air filters.	tpu	14-17	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
30409409-6	2019	Group B: milrinone was given as an infusion of 0.5mug.kg-1.min-1 without loading dose for 21 days.	Milrinone	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
28035604-8	2019	OH played an important role in the degradation of EDTA, whose yield and productive rate were 3.13 mg/L and 0.157 mg/(L min-1), respectively.	Edetic Acid	50-54	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
30353450-6	2019	The rate of glucose utilisation during exercise was also significantly reduced (85.76 +- 23.95 vs. 56.67 +- 15.09 muM kg-1 min-1).	Glucose	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
30662529-1	2019	The novel tumor targeted nano-drug C-PC/CMC-CD59sp nanoparticles were constructed with carbocymethyl chitosan (CMC), C-phycocyanin (C-PC) and CD59 specific ligand peptide (CD59sp).	cmc	40-43	CD59 molecule (CD59 blood group)	Homo sapiens	44-48
30662529-1	2019	The novel tumor targeted nano-drug C-PC/CMC-CD59sp nanoparticles were constructed with carbocymethyl chitosan (CMC), C-phycocyanin (C-PC) and CD59 specific ligand peptide (CD59sp).	carbocymethyl chitosan	87-109	CD59 molecule (CD59 blood group)	Homo sapiens	44-48
29941331-8	2019	Analysis revealed that the greatest number of cases (44.6%) occurred in those with an estimated glomerular filtration rate (eGFR) between 15 and 60 mL/min/1.73 m2 and who initiated allopurinol at a dose of 100 mg/day.	Allopurinol	181-192	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
30844815-7	2019	CONCLUSION: There is a preferential time-dependent decline in the expression of CD59, but not of CD55, on stored RBCs, the in vivo significance of which in relation to the response to PRBC transfusion needs further investigation.	prbc	184-188	CD59 molecule (CD59 blood group)	Homo sapiens	80-84
30262088-4	2019	The sample in the presence of 70% hydrogen peroxide is circulated on an 8 W UV lamp at the flow rate of 1 mL min-1 for 45 min.	Hydrogen Peroxide	34-51	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
30613016-5	2018	RESULTS: The LD50 of continuously infused mivacurium was 8.94 mug?kg-1?min-1 (95% CI: 8.89- 8.99 mug?kg-1?min-1) during thyroid surgery, which did not affect neurological function monitoring.	Mivacurium	42-52	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
30613016-5	2018	RESULTS: The LD50 of continuously infused mivacurium was 8.94 mug?kg-1?min-1 (95% CI: 8.89- 8.99 mug?kg-1?min-1) during thyroid surgery, which did not affect neurological function monitoring.	Mivacurium	42-52	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
30613016-8	2018	CONCLUSIONS: In patients undergoing thyroid surgery under anesthesia maintained by inhalation and intravenous infusion, the LD50 of mivacurium was 8.94 mug?kg-1?min-1 (95% CI: 8.89-8.99 mug?kg-1?min-1) for continuous infusion, which does not cause serious adverse effects during the operation.	Mivacurium	132-142	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
30613016-8	2018	CONCLUSIONS: In patients undergoing thyroid surgery under anesthesia maintained by inhalation and intravenous infusion, the LD50 of mivacurium was 8.94 mug?kg-1?min-1 (95% CI: 8.89-8.99 mug?kg-1?min-1) for continuous infusion, which does not cause serious adverse effects during the operation.	Mivacurium	132-142	CD59 molecule (CD59 blood group)	Homo sapiens	195-200
30637211-4	2018	Results: Added to the inspiration air at a flow rate of 2-3 Liter min-1, CO2 increased the respiratory volume up to 25-30 Liter min-1, ensuring forced AHH exhalation.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	73-76	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
30637211-4	2018	Results: Added to the inspiration air at a flow rate of 2-3 Liter min-1, CO2 increased the respiratory volume up to 25-30 Liter min-1, ensuring forced AHH exhalation.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	73-76	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
31458409-7	2018	The cell power increased with the increasing flow rate of the glucose solution up to 50 cm3 min-1 and leveled off thereafter.	Glucose	62-69	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
30585187-3	2018	Faceted cuspidine and CaSiO3 are co-precipitated when the cooling rate is less than 50  C min-1.	cuspidine	8-17	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
30585187-3	2018	Faceted cuspidine and CaSiO3 are co-precipitated when the cooling rate is less than 50  C min-1.	casio3	22-28	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
30585187-4	2018	The phases transform from Ca4Si2O7F2 and CaSiO3 to Ca4Si2O7F2 at the cooling rate of 50  C min-1.	ca4si2o7f2	51-61	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
30585187-8	2018	With decreasing temperature, the morphology of CaAl2O4 firstly becomes dendritic, and then the dendritic quality gradually changes to a large-mesh blocky shape at the cooling rates of 100  C min-1, 200  C min-1, and 500  C min-1.	caal2o4	47-54	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
30585187-8	2018	With decreasing temperature, the morphology of CaAl2O4 firstly becomes dendritic, and then the dendritic quality gradually changes to a large-mesh blocky shape at the cooling rates of 100  C min-1, 200  C min-1, and 500  C min-1.	caal2o4	47-54	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
30585187-8	2018	With decreasing temperature, the morphology of CaAl2O4 firstly becomes dendritic, and then the dendritic quality gradually changes to a large-mesh blocky shape at the cooling rates of 100  C min-1, 200  C min-1, and 500  C min-1.	caal2o4	47-54	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	2,3,4,5,6-pentafluorophenol	3-9	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	2,3,4,5,6-pentafluorophenol	3-9	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	c6cl5oh	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	c6cl5oh	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	Phenoxy radical	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	Phenoxy radical	39-46	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	Phenol	98-104	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	Phenol	98-104	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	2-norbornene	143-153	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	2-norbornene	143-153	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	2,3,4,5,6-pentafluorophenol	186-192	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
30444254-2	2018	of C6F5OH or C6Cl5OH via the immediate phenoxy exchange; the activity was affected by the kind of phenol added [activity (TOF) in the ROMPs of norbornene: 46 200 min-1 (upon addition of C6F5OH) vs. 37.3 min-1 (by 1)].	2,3,4,5,6-pentafluorophenol	186-192	CD59 molecule (CD59 blood group)	Homo sapiens	203-208
30558325-5	2018	The separation was performed by gradient elution of acetonitrile/methanol and 2% water solution of ammonium acetate at flow rate 2.0 mL min-1.	ammonium acetate	99-115	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
30516142-4	2018	It was found that the Na5FeSi4O12 phase crystallizes at ~720  C from the glass and melts at ~830  C when heated at a rate of 10  C min-1.	na5fesi4o12	22-33	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
30193213-4	2018	Consequently, the dissolved CO2 concentration in the microalgae suspension of the proposed PBR was increased by 26.0% compared to that in the PBR without PIAT internals when 15% CO2 (v/v) was aerated at a rate of 15 mL min-1.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	28-31	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
29761242-12	2018	CONCLUSIONS: Benzbromarone and febuxostat could reduce SUA and maintain renal function in chronic kidney disease (CKD) patients with eGFR 20-60 mL/min/1.73 m2.	Benzbromarone	13-26	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
29761242-12	2018	CONCLUSIONS: Benzbromarone and febuxostat could reduce SUA and maintain renal function in chronic kidney disease (CKD) patients with eGFR 20-60 mL/min/1.73 m2.	Febuxostat	31-41	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
30206692-5	2018	[Formula: see text]O2 and [Formula: see text]CO2 (L min-1) were unchanged in CONT-BH (2.73 +- 0.14 and 3.16 +- 0.38) and greater in Fartlek (2.85 +- 0.12 and 3.43 +- 0.16), compared to CONT (2.71 +- 0.12 and 3.12 +- 0.13).	Carbon Dioxide	45-48	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
30015165-9	2018	Importantly, the as-designed bioinspired strategy led to a state-of-the-art design that was capable of reversibly controlling the flow rate (J) of ciprofloxacin from 12.10 to 4.93 mg min-1 cm-2 in less than a few minutes using light.	Ciprofloxacin	147-160	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
30475357-4	2018	Adduct 1a undergoes unimolecular hydrogen chloride elimination with a first-order rate constant of k1 = 3.03(7) x 10-2 min-1 in toluene at 100  C. This rate constant is in very good agreement with the one derived (k1 = 3.18 x 10-2 min-1) from computed activation parameters (DeltaH 373.15 = 28.1 kcal mol-1, DeltaS 373.15 = 1.56 eu, DeltaG 373.15 = 27.6 kcal mol-1).	Hydrochloric Acid	33-50	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
30475357-4	2018	Adduct 1a undergoes unimolecular hydrogen chloride elimination with a first-order rate constant of k1 = 3.03(7) x 10-2 min-1 in toluene at 100  C. This rate constant is in very good agreement with the one derived (k1 = 3.18 x 10-2 min-1) from computed activation parameters (DeltaH 373.15 = 28.1 kcal mol-1, DeltaS 373.15 = 1.56 eu, DeltaG 373.15 = 27.6 kcal mol-1).	Hydrochloric Acid	33-50	CD59 molecule (CD59 blood group)	Homo sapiens	231-236
30475357-4	2018	Adduct 1a undergoes unimolecular hydrogen chloride elimination with a first-order rate constant of k1 = 3.03(7) x 10-2 min-1 in toluene at 100  C. This rate constant is in very good agreement with the one derived (k1 = 3.18 x 10-2 min-1) from computed activation parameters (DeltaH 373.15 = 28.1 kcal mol-1, DeltaS 373.15 = 1.56 eu, DeltaG 373.15 = 27.6 kcal mol-1).	Toluene	128-135	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
30475357-4	2018	Adduct 1a undergoes unimolecular hydrogen chloride elimination with a first-order rate constant of k1 = 3.03(7) x 10-2 min-1 in toluene at 100  C. This rate constant is in very good agreement with the one derived (k1 = 3.18 x 10-2 min-1) from computed activation parameters (DeltaH 373.15 = 28.1 kcal mol-1, DeltaS 373.15 = 1.56 eu, DeltaG 373.15 = 27.6 kcal mol-1).	Toluene	128-135	CD59 molecule (CD59 blood group)	Homo sapiens	231-236
30475357-4	2018	Adduct 1a undergoes unimolecular hydrogen chloride elimination with a first-order rate constant of k1 = 3.03(7) x 10-2 min-1 in toluene at 100  C. This rate constant is in very good agreement with the one derived (k1 = 3.18 x 10-2 min-1) from computed activation parameters (DeltaH 373.15 = 28.1 kcal mol-1, DeltaS 373.15 = 1.56 eu, DeltaG 373.15 = 27.6 kcal mol-1).	deltas	308-314	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
30475357-4	2018	Adduct 1a undergoes unimolecular hydrogen chloride elimination with a first-order rate constant of k1 = 3.03(7) x 10-2 min-1 in toluene at 100  C. This rate constant is in very good agreement with the one derived (k1 = 3.18 x 10-2 min-1) from computed activation parameters (DeltaH 373.15 = 28.1 kcal mol-1, DeltaS 373.15 = 1.56 eu, DeltaG 373.15 = 27.6 kcal mol-1).	deltas	308-314	CD59 molecule (CD59 blood group)	Homo sapiens	231-236
30219858-9	2018	Results: Total fatty acid oxidation rate was higher in patients with l-carnitine treatment during exercise than without treatment [12.3 (SD, 3.7) vs 8.5 (SD, 4.6) micromol x kg-1 x min-1; P = 0.008].	Carnitine	69-80	CD59 molecule (CD59 blood group)	Homo sapiens	181-186
30219858-10	2018	However, the fatty acid oxidation rate was still lower in patients treated with l-carnitine than in the healthy controls [29.5 (SD, 10.1) micromol x kg-1 x min-1; P &lt; 0.001] and in the l-carnitine group without treatment it was less than one third of that in the healthy controls (P &lt; 0.001).	Carnitine	80-91	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
29520080-13	2018	Among patients with minor stroke or TIA taking clopidogrel-aspirin treatment, CYP2C19 LOF carrier state was associated with higher risk of new stroke in those with eGFR &lt; 75 ml/min/1.73 m2.	Clopidogrel	47-58	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
29520080-13	2018	Among patients with minor stroke or TIA taking clopidogrel-aspirin treatment, CYP2C19 LOF carrier state was associated with higher risk of new stroke in those with eGFR &lt; 75 ml/min/1.73 m2.	Aspirin	59-66	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
30249353-9	2018	Total carbohydrate and fat oxidation during running decreased (0.76 vs. 1.82 g min-1; delta=-3.9) and increased (0.91 vs. 0.54 g min-1; delta=3.7), respectively, more profoundly on RP as the MSUM progressed.	Carbohydrates	6-18	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
30717531-4	2018	The results showed that the optimum preparation conditions for glycyrrhizin nano-sponges were as follows:The proportion of main drug and auxiliary drug was 1:2; the proportion of crosslinking agent DPC and beta-CD was 4:1; stirring temperature 45  C for 4.8 h at 245 r min-1.	Glycyrrhizic Acid	63-75	CD59 molecule (CD59 blood group)	Homo sapiens	269-274
30842838-3	2019	When the temperature of the solution is oscillated between -5 and 38  C at a rate of 2 K min-1, Deltaepsilon reaches maxima twice during a single temperature oscillation, which is called a chemical CD oscillation phenomenon.	Cadmium	198-200	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
30842838-5	2019	In addition, the chemical CD oscillation appears, when temperature oscillation occurs at a rate of 2 K min-1, and higher and lower rates provide a single maximum, a process referred to as the chemical resonance phenomenon.	Cadmium	26-28	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
30398509-4	2018	Stress oscillation of PBS is observed when deformed at a range of elongation rates from 10 to 200 mm min-1, and the fluctuation magnitude decays as the deformation temperature increases from 23 to 100  C. Periodic transparent/opaque bands form during necking of PBS, which consists of alternating regions of highly oriented crystalline zones and microcavities due to crazing and voiding, although the degree of crystallinity did not change significantly in the bands.	bionole	22-25	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
31458173-6	2018	The rate constants (min-1) followed the trend: ZYH (26 x 10-4)   LaFeO3 (25 x 10-4) &gt; ZrO2 (22 x 10-4) &gt; Fe2O3   no catalyst (16 x 10-4).	lanthanum iron oxide	65-71	CD59 molecule (CD59 blood group)	Homo sapiens	20-25
31458173-6	2018	The rate constants (min-1) followed the trend: ZYH (26 x 10-4)   LaFeO3 (25 x 10-4) &gt; ZrO2 (22 x 10-4) &gt; Fe2O3   no catalyst (16 x 10-4).	zirconium oxide	89-93	CD59 molecule (CD59 blood group)	Homo sapiens	20-25
31458173-6	2018	The rate constants (min-1) followed the trend: ZYH (26 x 10-4)   LaFeO3 (25 x 10-4) &gt; ZrO2 (22 x 10-4) &gt; Fe2O3   no catalyst (16 x 10-4).	Iron(III) oxide	111-116	CD59 molecule (CD59 blood group)	Homo sapiens	20-25
30628230-3	2018	The experimental results showed that at an aerobic aeration rate of 0.8 L min-1 and aerobic duration time of 150 min, the effluent PO43--P concentration was about 1.5 mg L-1, with the effluent NH4+-N and NO3--N concentrations gradually decreasing from 10.28 and 8.14 mg L-1 to 0 and 2.27 mg L-1, respectively, and effluent NO2--N concentration increasing to 1.81 mg L-1.	po43--p	131-138	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
30391994-0	2018	Expression of the CD59 Glycoprotein Precursor is Upregulated in an Estrogen Receptor-alpha (ER-alpha)-Negative and a Tamoxifen-Resistant Breast Cancer Cell Line In Vitro.	Tamoxifen	117-126	CD59 molecule (CD59 blood group)	Homo sapiens	18-35
30391994-5	2018	Here, we report that CD59, a phosphatidylinositol-anchored glycoprotein, is a candidate resistant gene for TAM therapies.	Phosphatidylinositols	29-49	CD59 molecule (CD59 blood group)	Homo sapiens	21-25
30391994-5	2018	Here, we report that CD59, a phosphatidylinositol-anchored glycoprotein, is a candidate resistant gene for TAM therapies.	Tamoxifen	107-110	CD59 molecule (CD59 blood group)	Homo sapiens	21-25
30391994-13	2018	Importantly, RNAi-mediated attenuation of CD59 was sufficient to rescue the resistance to TAM in the TAMR-MCF-7 cells.	Tamoxifen	90-93	CD59 molecule (CD59 blood group)	Homo sapiens	42-46
30391994-14	2018	CONCLUSIONS In summary, our results proposed a candidate biomarker for predicting TAM resistance in ERa-positive breast cancer via targeting CD59, therefore it could be a novel therapeutic option.	Tamoxifen	82-85	CD59 molecule (CD59 blood group)	Homo sapiens	141-145
30209888-9	2018	The hydrogen gas evolution rate of the NiCo2 S4 /Co9 S8 heterostructure was determined to be 2.29 mumol min-1 .	Hydrogen	4-12	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
29971804-6	2018	RESULTS: Included studies demonstrated significant positive effects of lisinopril on proteinuric kidney disease; however, lisinopril caused a slight reduction of glomerular filtration rate (GFR) especially for patients with GFR &lt; 90 ml min-1 .	Lisinopril	122-132	CD59 molecule (CD59 blood group)	Homo sapiens	239-244
30336856-9	2018	RESULTS: Mean remifentanil infusion rate [mean (standard deviation)] was significantly higher in the sevoflurane group than in the desflurane group [0.192 (0.064) vs. 0.099 (0.033) mug kg-1 min-1; difference, 0.093 (95% confidence interval, 0.071-0.115); P&lt;0.001].	Remifentanil	14-26	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
30336856-9	2018	RESULTS: Mean remifentanil infusion rate [mean (standard deviation)] was significantly higher in the sevoflurane group than in the desflurane group [0.192 (0.064) vs. 0.099 (0.033) mug kg-1 min-1; difference, 0.093 (95% confidence interval, 0.071-0.115); P&lt;0.001].	Sevoflurane	101-112	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
30203466-10	2018	The basal microvascular flow of patients with peak oxygen consumption below 16.0 mL kg-1 min-1 was superior to that of patients with values greater than 16.0 mL kg-1 min-1 (P = .0046).	Oxygen	51-57	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
30255553-5	2018	Patients with peak oxygen uptake of &lt;13.1 ml O2  kg-1  min-1 and ventilatory equivalent for carbon dioxide at anaerobic threshold &gt;=34 are associated with increased risk of postoperative mortality at 2 years.	Oxygen	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
30255553-5	2018	Patients with peak oxygen uptake of &lt;13.1 ml O2  kg-1  min-1 and ventilatory equivalent for carbon dioxide at anaerobic threshold &gt;=34 are associated with increased risk of postoperative mortality at 2 years.	Oxygen	48-50	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
30078416-4	2018	The conversion could reach 96.69% in 16 min and the apparent rate constant based on rGO is derived to be 0.55 min-1 when the concentration of AgNC/GSH-rGO is 0.04 mg mL-1.	SILVER CYANIDE	142-146	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
30078416-4	2018	The conversion could reach 96.69% in 16 min and the apparent rate constant based on rGO is derived to be 0.55 min-1 when the concentration of AgNC/GSH-rGO is 0.04 mg mL-1.	Glutathione	147-150	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
30242837-10	2018	We found that (1) plasma hyperosmolality suppressed both components in hyperthermia, (2) the suppression was released by drinking 200 mL of water simultaneously with enhanced cutaneous vasodilatation and sweating responses, and (3) a rapid infusion at 1.0 and 0.2 ml min-1  kg-1 for the first 10 min and the following 20 min, respectively, increased the synchronized component and cutaneous vasodilatation in diuretic-induced hypovolaemia greater than those in a time control; at 0.1 ml min-1  kg-1 for 30 min no greater increases in the non-synchronized component and sweating responses were observed during rapid infusion than in the time control.	Water	140-145	CD59 molecule (CD59 blood group)	Homo sapiens	267-278
30242837-10	2018	We found that (1) plasma hyperosmolality suppressed both components in hyperthermia, (2) the suppression was released by drinking 200 mL of water simultaneously with enhanced cutaneous vasodilatation and sweating responses, and (3) a rapid infusion at 1.0 and 0.2 ml min-1  kg-1 for the first 10 min and the following 20 min, respectively, increased the synchronized component and cutaneous vasodilatation in diuretic-induced hypovolaemia greater than those in a time control; at 0.1 ml min-1  kg-1 for 30 min no greater increases in the non-synchronized component and sweating responses were observed during rapid infusion than in the time control.	Water	140-145	CD59 molecule (CD59 blood group)	Homo sapiens	487-498
29619870-7	2018	Pooled estimate for eGFR was in favor of lowering serum uric acid therapy with a mean difference (MD) of 3.88 ml/min/1.73 m2, 95% CI 1.26-6.49 ml/min/1.73 m2, p = .004 and this was consistent with results for serum creatinine.	Uric Acid	56-65	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
29619870-7	2018	Pooled estimate for eGFR was in favor of lowering serum uric acid therapy with a mean difference (MD) of 3.88 ml/min/1.73 m2, 95% CI 1.26-6.49 ml/min/1.73 m2, p = .004 and this was consistent with results for serum creatinine.	Uric Acid	56-65	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
30386431-10	2018	Among 12 terpenes studied, limonene appears to be the most reasonable short-term target because of its large market size (~ 160 million $/year in the US) and the relatively easier to achieve break-even yield (~ 30%, assuming a 14 wt% feed glucose concentration and 0.1 min-1 VVM).	Limonene	27-35	CD59 molecule (CD59 blood group)	Homo sapiens	269-274
30326091-0	2018	Metformin use was linked to hospitalization for acidosis at 6 y only in patients with eGFR &lt; 30 mL/min/1.73 m2.	Metformin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
30307991-5	2018	Only the beta-alanine group presented a significant reduction in [Formula: see text] expressed in absolute values (PRE = 3.3+-0.6L min-1; POST = 3.0+-0.4L min-1; p = .021).	beta-Alanine	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
30307991-5	2018	Only the beta-alanine group presented a significant reduction in [Formula: see text] expressed in absolute values (PRE = 3.3+-0.6L min-1; POST = 3.0+-0.4L min-1; p = .021).	beta-Alanine	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
30286760-6	2018	RESULTS: Maximal oxygen uptake was 54.78 +- 3.13 mL min- 1 kg- 1, and gross efficiency was &gt; 22% at each load intensity and experimental condition.	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	52-64
29877590-3	2018	This study aims to determine the time course of major bleeding after major orthopaedic surgery, identify predictors of bleeding and simulate the effect of a reduced dose of fondaparinux on bleeding for patients with moderate renal impairment (creatinine clearance = 20-50 ml min-1 ).	Fondaparinux	173-185	CD59 molecule (CD59 blood group)	Homo sapiens	275-280
29920408-2	2018	The pseudo-first-order rate constants of methadone degradation under acidic conditions ([methadone] = 0.2 muM, [free chlorine] = 4 muM, and pH = 4) for sunlight/FC and sunlight photolysis are 7.0 +- 1.1 x 10-2 min-1 and 1.4 +- 0.2 x 10-2 min-1, respectively.	Methadone	41-50	CD59 molecule (CD59 blood group)	Homo sapiens	210-243
29920408-2	2018	The pseudo-first-order rate constants of methadone degradation under acidic conditions ([methadone] = 0.2 muM, [free chlorine] = 4 muM, and pH = 4) for sunlight/FC and sunlight photolysis are 7.0 +- 1.1 x 10-2 min-1 and 1.4 +- 0.2 x 10-2 min-1, respectively.	Methadone	89-98	CD59 molecule (CD59 blood group)	Homo sapiens	210-243
29543081-9	2018	Acceleration activities (n min-1) at moderate and high intensities decreased in all groups across QTRs with moderate to very large ES (ES: 0.4-1.4).	Einsteinium	131-133	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
29710576-4	2018	With an external resistance of 7.8 Omega and a water (hot side) flow rate of 75 mL min-1, a maximum normalized energy recovery of 4.5 x 10-4 kWh m-3 was achieved under a 2.8  C temperature gradient (DeltaT).	Water	47-52	CD59 molecule (CD59 blood group)	Homo sapiens	83-88
30338015-7	2018	The MP + Ex group (Delta+4.4 ml kg-1 min-1) had a greater change from baseline compared to the MP group (Delta-2.7 ml kg-1 min-1, p = 0.002), and PD + Ex group (Delta-0.3 ml kg-1 min-1, p = 0.03).	mp +	4-8	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
30338015-7	2018	The MP + Ex group (Delta+4.4 ml kg-1 min-1) had a greater change from baseline compared to the MP group (Delta-2.7 ml kg-1 min-1, p = 0.002), and PD + Ex group (Delta-0.3 ml kg-1 min-1, p = 0.03).	mp +	4-8	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
30338015-7	2018	The MP + Ex group (Delta+4.4 ml kg-1 min-1) had a greater change from baseline compared to the MP group (Delta-2.7 ml kg-1 min-1, p = 0.002), and PD + Ex group (Delta-0.3 ml kg-1 min-1, p = 0.03).	mp +	4-8	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
30455014-9	2018	In addition, the increased air-flow rates greatly accelerated water removal with high bio-energy efficiencies, especially at 0.8 L min-1 kg-1.	Water	62-67	CD59 molecule (CD59 blood group)	Homo sapiens	131-141
30262533-7	2018	However, we detected a germ-line mutation and a somatic microdeletion in chromosome 20q including PIGT; PIGT is essential for transferring GPI anchor to the precursors of CD59 and CD55, which play important roles in complement regulation.	GPI 1046	139-142	CD59 molecule (CD59 blood group)	Homo sapiens	171-175
30212529-3	2018	The maximal oxygen uptake during running was higher (p = 0.001; large effect size) vs. cycling (49.2+-3.8 mL kg-1 min-1 vs. 44.7+-5.7 mL kg-1 min-1, respectively).	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
30212529-3	2018	The maximal oxygen uptake during running was higher (p = 0.001; large effect size) vs. cycling (49.2+-3.8 mL kg-1 min-1 vs. 44.7+-5.7 mL kg-1 min-1, respectively).	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
29702321-6	2018	In the macro-reaction system for 4-nitrophenol (4-NP) reduction, the as-prepared Fe-Fe2O3@PZS@Ni(OH)2 NCs show an apparent rate constant of about 0.60 min-1.	4-nitrophenol	33-46	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
29702321-6	2018	In the macro-reaction system for 4-nitrophenol (4-NP) reduction, the as-prepared Fe-Fe2O3@PZS@Ni(OH)2 NCs show an apparent rate constant of about 0.60 min-1.	4-nitrophenol	48-52	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
29702321-6	2018	In the macro-reaction system for 4-nitrophenol (4-NP) reduction, the as-prepared Fe-Fe2O3@PZS@Ni(OH)2 NCs show an apparent rate constant of about 0.60 min-1.	fe-fe2o3	81-89	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
29923148-14	2018	An increase in [Formula: see text]O2max of 10 mL kg-1 min-1 had small effects with low and normal CHO availability (29, +- 44 and 67, +- 15 mmol kg-1, respectively) and a moderate effect with high CHO availability (80, +- 40 mmol kg-1).	CAV protocol	98-101	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
29923148-14	2018	An increase in [Formula: see text]O2max of 10 mL kg-1 min-1 had small effects with low and normal CHO availability (29, +- 44 and 67, +- 15 mmol kg-1, respectively) and a moderate effect with high CHO availability (80, +- 40 mmol kg-1).	CAV protocol	197-200	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
30177117-12	2018	In both groups of patients with estimated glomerular filtration rate above 60 mL/min/1.72 m2, vitamin D was significantly higher.	Vitamin D	94-103	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
32055559-1	2018	Adding to the complexity of caring for critically ill patients is the fact that many of them have a creatinine clearance that exceeds 130 mL/min/1.73 m2.	Creatinine	100-110	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
29887347-8	2018	Estimated oxygen consumption was highest during ingress hikes and was significantly different from all other hike types on fire assignments (ingress: 22+-12, shift: 19+-12, egress: 19+-12 mL kg-1 min-1; P=0.01).	Oxygen	10-16	CD59 molecule (CD59 blood group)	Homo sapiens	196-201
29887347-9	2018	Oxygen consumption was higher during training hikes (34+-14 mL kg-1 min-1) than during job-related hikes (P&lt;0.01).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
30252653-8	2018	The maximum adsorption capacity of 13.47 mg g-1 for P, 16.13 mg g-1 for P-NaCl, 22.10 mg g-1 for P-KCl, 30.05 mg g-1 for P-CaCl2 was attained at an initial influent concentration of 300 mg g-1, bed height of 22 cm, and flow rate of 10 mL min-1.	Calcium Chloride	123-128	CD59 molecule (CD59 blood group)	Homo sapiens	238-243
30220142-7	2018	In 149 patients who were treated with cisplatin-based chemotherapy, the average serum creatinine level increased by 1.31 mumol/L and eGFR improved by 0.14 ml min-1 (1.73 m2)-1, but the differences were not statistically significant (P&gt;0.05).	Cisplatin	38-47	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
30136461-4	2018	Hence, the measure of serum bicarbonate level should be part of the systematic follow-up of CKD patients of whom glomerular filtration rate decreases below 50 ml/min/1.73m2.	Bicarbonates	28-39	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
29873890-6	2018	The Ir-coordinated assemblies showed a turnover frequency of 13 min-1 , which was comparable to those previously reported for molecular water oxidation catalysts.	Water	136-141	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
30128312-5	2018	23 cm3 min-1 with purity of 98-99% was successfully achieved, and remained stable over 120 h, with a methane conversion of 71-73% on the other side of perovskite membrane.	Methane	101-108	CD59 molecule (CD59 blood group)	Homo sapiens	7-12
30128312-5	2018	23 cm3 min-1 with purity of 98-99% was successfully achieved, and remained stable over 120 h, with a methane conversion of 71-73% on the other side of perovskite membrane.	perovskite	151-161	CD59 molecule (CD59 blood group)	Homo sapiens	7-12
29979032-4	2018	Of these, the Cu(II)BEPA-Pr and Cu(II)Me3TACN complexes provide biomedically useful NO fluxes from the surface of the catheters, &gt;2 x 10-10 mol min-1 cm-2, under conditions mimicking the bloodstream environment.	cu(ii)bepa-pr	14-27	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
29979032-4	2018	Of these, the Cu(II)BEPA-Pr and Cu(II)Me3TACN complexes provide biomedically useful NO fluxes from the surface of the catheters, &gt;2 x 10-10 mol min-1 cm-2, under conditions mimicking the bloodstream environment.	cu(ii)me3tacn	32-45	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
29909456-6	2018	The apparent Michaelis-Menten constant and the maximum rate of the enzyme reactor were determined (Km = 32.3 mM, Vmax = 33.3 mM min-1) by a chiral ligand exchange capillary electrochromatography protocol with L-glutamine as the substrate.	Glutamine	209-220	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
29705637-2	2018	The FZG1 photocatalyst, having the weight ratio of 1:1 for the initial urea and Fe3O4-ZnO (Fe-ZnO), presented the highest sulfamethoxazole (SMX) degradation rate of 0.0351 (min-1), which was 2.6 times higher than that of pristine ZnO.	fe3o4-zno	80-89	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
29705637-2	2018	The FZG1 photocatalyst, having the weight ratio of 1:1 for the initial urea and Fe3O4-ZnO (Fe-ZnO), presented the highest sulfamethoxazole (SMX) degradation rate of 0.0351 (min-1), which was 2.6 times higher than that of pristine ZnO.	fe-zno	91-97	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
29705637-2	2018	The FZG1 photocatalyst, having the weight ratio of 1:1 for the initial urea and Fe3O4-ZnO (Fe-ZnO), presented the highest sulfamethoxazole (SMX) degradation rate of 0.0351 (min-1), which was 2.6 times higher than that of pristine ZnO.	Sulfamethoxazole	122-138	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
29705637-2	2018	The FZG1 photocatalyst, having the weight ratio of 1:1 for the initial urea and Fe3O4-ZnO (Fe-ZnO), presented the highest sulfamethoxazole (SMX) degradation rate of 0.0351 (min-1), which was 2.6 times higher than that of pristine ZnO.	Sulfamethoxazole	140-143	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
29573529-3	2018	Dapagliflozin decreased albuminuria by 43.9% (95% CI, 30.3%-54.8%) and eGFR by 5.1 (2.0-8.1) mL/min/1.73m2 compared to placebo.	dapagliflozin	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
29752257-4	2018	MRP1 expressed in HEK293 cells reduced the toxicity of the major urinary arsenic metabolite dimethylarsinic acid (DMAV), and HEK-WT-MRP1-enriched vesicles transported DMAV with high apparent affinity and capacity (Km 0.19 microM, Vmax 342 pmol mg-1protein min-1).	Dimethylarsinate	167-171	CD59 molecule (CD59 blood group)	Homo sapiens	256-261
30369300-9	2018	This was paralleled by a rise in peak oxygen uptake (VO2peak = 29.14 +- 5.34 versus 32.48 +- 5.75 ml kg-1 min-1, p = .04).	Oxygen	38-44	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
29722620-5	2018	Infusion of KCl or SNP elevated resting FVC similarly before the onset of exercise (control: 39 +- 6 vs. KCl: 81 +- 12 and SNP: 82 +- 13 ml min-1 100 mmHg-1; both P &lt; 0.05 vs. control).	Potassium Chloride	12-15	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
29458572-10	2018	This research reports the complete degradation of rhodium boride (RhB) within 50 min by means of mesoporous ZnO hollow spheres and nanorods with a degradation rate of 0.0978 min-1.	rhodium boride	50-64	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
29458572-10	2018	This research reports the complete degradation of rhodium boride (RhB) within 50 min by means of mesoporous ZnO hollow spheres and nanorods with a degradation rate of 0.0978 min-1.	rhb	66-69	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
29458620-3	2018	The kinetics of the catalytic reaction follows the quasi-first order reaction and its rate constant (kapp) values for CoFe2O4, NiFe2O4 and CuFe2O4 are calculated to be 1.62, 11.74 and 37.28 min-1, respectively.	cobalt ferrite	118-125	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
29458620-3	2018	The kinetics of the catalytic reaction follows the quasi-first order reaction and its rate constant (kapp) values for CoFe2O4, NiFe2O4 and CuFe2O4 are calculated to be 1.62, 11.74 and 37.28 min-1, respectively.	nickel ferrite	127-134	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
29458620-3	2018	The kinetics of the catalytic reaction follows the quasi-first order reaction and its rate constant (kapp) values for CoFe2O4, NiFe2O4 and CuFe2O4 are calculated to be 1.62, 11.74 and 37.28 min-1, respectively.	CuFe2O4	139-146	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
30032750-1	2018	CD59 and decay-accelerating factor (DAF) are glycosylphosphatidylinositol (GPI)-anchored complement regulatory proteins critical for regulating complement activation on the host cell surface.	Glycosylphosphatidylinositols	45-73	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
30147354-6	2018	The estimated glomerular filtration rate (eGFR) by the formula developed by Japanese Society of Nephrology (in mL/min/1.73 m2) decreased: C group (from 28.3+-13.6 to 23.0+-12.3, p=0.09), T group (from 22.7+-12.4 to 19.4+-12.2, p=0.18), but both did not reach significance.	Carbon	138-139	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
29709810-5	2018	A continuous aeration rate of 0.5 L kg-1 dry matter min-1 gave the best biodrying performance (the highest water-removal rate, biodrying index, and sorting efficiency, 0.5 kg kg-1, 4.12, and 86.87%, respectively, and the highest lower heat value (LHV) and heat utilization rate, 9440 kJ kg-1 and 68.3%, respectively).	Water	107-112	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
29709810-5	2018	A continuous aeration rate of 0.5 L kg-1 dry matter min-1 gave the best biodrying performance (the highest water-removal rate, biodrying index, and sorting efficiency, 0.5 kg kg-1, 4.12, and 86.87%, respectively, and the highest lower heat value (LHV) and heat utilization rate, 9440 kJ kg-1 and 68.3%, respectively).	lhv	247-250	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
29709810-6	2018	There was an optimum aeration rate, water loss reaching a maximum at an aeration rate of 0.5 L kg-1 DM min-1 and not increasing further as the aeration rate increased further.	Water	36-41	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
29762654-13	2018	Disposable latex gloves displayed the greatest total isocyanate permeation rate (4.11 ng/cm2 min-1), followed by the vinyl and nitrile gloves, respectively.	Isocyanates	53-63	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
29910050-1	2018	In older patients (70 +- 7 years) with chronic well-compensated heart failure with preserved ejection and controlled blood pressure, 6 months treatment with aliskiren (direct renin inhibitor) showed non-significant trends for modest improvements in peak exercise oxygen consumption (14.9 +- 0.2 mL kg-1 min-1 versus 14.4 +- 0.2 mL kg-1 min-1; P = .10, trend) and ventilatory anaerobic threshold (888 +- 19 mL/min versus 841 +- 18 mL/min; P = .08).	aliskiren	157-166	CD59 molecule (CD59 blood group)	Homo sapiens	303-308
29910050-1	2018	In older patients (70 +- 7 years) with chronic well-compensated heart failure with preserved ejection and controlled blood pressure, 6 months treatment with aliskiren (direct renin inhibitor) showed non-significant trends for modest improvements in peak exercise oxygen consumption (14.9 +- 0.2 mL kg-1 min-1 versus 14.4 +- 0.2 mL kg-1 min-1; P = .10, trend) and ventilatory anaerobic threshold (888 +- 19 mL/min versus 841 +- 18 mL/min; P = .08).	aliskiren	157-166	CD59 molecule (CD59 blood group)	Homo sapiens	336-341
28782878-8	2018	CFS workload decreased on day 2, alongside a decrease in HR but with an increase in V O2 (ml  kg  min-1 ).	Oxygen	86-88	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
29626593-3	2018	The study was initially carried out considering a feed flow rate of 80 ml min-1: using acetone, the mean particle size was lower (163 +- 7 nm) and the Zeta potential was higher (31.4 +- 37 mV) with the MIVM, with respect to the CIJM (265 +- 31 nm and 9.8 +- 2.4 mV, respectively).	Acetone	87-94	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
29714043-14	2018	Predictive modelling through multivariable logistic regression analysis showed that female sex (odds ratio = 9.82) and increasing maximal response to noradrenaline (odds ratio = 1.19, per 1 mN increase) were associated with a higher probability of the occurrence of vasomotion, whereas increasing kidney function (expressed as estimated glomerular filtration rate) was associated with a lower probability (odds ratio = 0.97, per 1 ml min-1  (1.73 m)-2 ].	Norepinephrine	150-163	CD59 molecule (CD59 blood group)	Homo sapiens	434-439
30042570-7	2018	The rehydration constant value was found as 16.5 min-1, showing the rapidity with that the water diffused into the powder in the most suitable condition.	Water	91-96	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
29457833-6	2018	As the solution pH increased from 5.0 to 8.0, the H2 O2 production rate decreased from 0.83 to 0.40 mum min-1 .	Hydrogen Peroxide	50-55	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
30032750-1	2018	CD59 and decay-accelerating factor (DAF) are glycosylphosphatidylinositol (GPI)-anchored complement regulatory proteins critical for regulating complement activation on the host cell surface.	Glycosylphosphatidylinositols	75-78	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
30032754-2	2018	Its pathology is driven by chronic complement dysregulation resulting from the lack of the glycosyl phosphatidyl inositol-linked regulators DAF and CD59 on susceptible erythrocytes.	Glycosylphosphatidylinositols	91-121	CD59 molecule (CD59 blood group)	Homo sapiens	148-152
30193519-3	2018	A molecular basis of PNH is a somatic mutation of PIGA gene causing a lack of glycosyl phosphatidyl inositol which binds many important antigens to cell surface membrane including inhibitors of activated complement CD59 and CD55 antigens.	Glycosylphosphatidylinositols	78-108	CD59 molecule (CD59 blood group)	Homo sapiens	215-219
30023934-4	2018	The photocatalytic degradation of Rhodamine B dye achieved under 120 min visible-light illumination is 94% by the RGO-BFO composite with a degradation rate of 1.86 x 10-2 min-1, which is 3.8 times faster than the BFO nanoparticles.	rhodamine B	34-45	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
30728987-6	2018	The average OP was 8.90 +- 7.15 and 1.41 +- 0.35 and was 11.4 +- 3.97 and 19.9 +- 8.67 (nmol min-1 mug PM10 -1) for water and methanol extracts on dusty and regular days, respectively, with the lowest value occurring on dusty days.	Water	116-121	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
29695656-3	2018	The maintenance dose of prasugrel 2.5 mg/day was prescribed for patients with a low body weight (&lt;=50 kg), elderly (&gt;=75 years), or renal insufficiency (eGFR &lt;=30 mL/min/1.73 m2).	Prasugrel Hydrochloride	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	175-180
29447666-2	2018	Argon was found as the best discharge gas under a flow rate of 50 mL min- 1 while the DBD power was optimum at 30 W. Analytical figures of merit including interference study of As, Se and Bi have been subsequently investigated and the results compared to those found in an externally heated quartz tube atomizer (QTA).	Argon	0-5	CD59 molecule (CD59 blood group)	Homo sapiens	69-75
29925007-4	2018	We have quantitatively compared MIN1PIPE with other existing partial methods using both synthetic and real datasets obtained from different animal models and show that MIN1PIPE has superior efficiency and precision in analyzing noisy miniscope calcium imaging data.	Calcium	244-251	CD59 molecule (CD59 blood group)	Homo sapiens	32-36
30857083-10	2018	Key controls on oxygen transfer efficiency within the aerated treatment system were also determined, revealing that standard oxygen transfer efficiency was inversely related to aeration rate between 1 L and 3 L min-1 and positively related to bed media depth between 1500 mm and 3000 mm.	Oxygen	125-131	CD59 molecule (CD59 blood group)	Homo sapiens	211-216
29779365-5	2018	We demonstrated H-ZIF-L-assembled polypropylene microfibers as a washable membrane filter with highly efficient PM removal property (92.5 +- 0.8% for PM2.5 and 99.5 +- 0.2% for PM10), low pressure drop (10.5 Pa at 25 L min-1), long-term stability, and superior recyclability.	Polypropylenes	34-47	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
30245542-7	2018	The fitted value of Ks =1.01 x 10-3 m min-1 at the Torrance drywell was consistent with the sandy soil texture at this site and the default value for sand in the HYDRUS soil catalog.	Potassium	20-22	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
30245542-8	2018	The drywell with this Ks = 1.01 x 10-3 m min-1 could easily infiltrate predicted surface runoff from a design rain event (~51.3 m3) within 5760 min (4 d).	Potassium	22-24	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
30245542-9	2018	In contrast, the fitted value of Ks=2.25 x 10-6 m min-1 at Fort Irwin was very low compared to the Torrance drywell and more than an order of magnitude smaller than the default value reported in the HYDRUS soil catalog for sandy clay loam at this site, likely due to clogging.	Potassium	33-35	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
29560563-4	2018	A normalized coefficient of variation of quantitative glucose influx constant, calculated as the ratio: standard deviation of the segmental Ki (min-1)/global Ki (min-1) was determined using a validated software (Carimas  2.4, Turku PET Centre).	Glucose	54-61	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
29560563-4	2018	A normalized coefficient of variation of quantitative glucose influx constant, calculated as the ratio: standard deviation of the segmental Ki (min-1)/global Ki (min-1) was determined using a validated software (Carimas  2.4, Turku PET Centre).	Glucose	54-61	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
29637614-4	2018	As a result of optimization studies, the analysis was carried out using Lux Cellulose-3, methanol as a mobile phase at a flow rate of 1 mL min-1 , and the detection wavelength was arranged to 230 nm.	Methanol	89-97	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
29772810-4	2018	Here, we refine a previously developed micropatterning approach combined with single molecule tracking to quantify the influence of the glycosylphosphatidylinositol-anchored (GPI-anchored) protein CD59 on its molecular environment directly in the live cell plasma membrane.	Glycosylphosphatidylinositols	136-164	CD59 molecule (CD59 blood group)	Homo sapiens	197-201
29502264-7	2018	CO was higher when inhaling O2-poor gas mixtures with or without CO2 (~ 17 L min-1) than in the other conditions (~ 14 L min-1, p &lt; 0.001).	Oxygen	28-30	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
29502264-7	2018	CO was higher when inhaling O2-poor gas mixtures with or without CO2 (~ 17 L min-1) than in the other conditions (~ 14 L min-1, p &lt; 0.001).	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	65-68	CD59 molecule (CD59 blood group)	Homo sapiens	77-82
29611451-3	2018	Global MR-derived BBB permeability ( Ktrans) was significantly higher in aSAH patients who subsequently developed DCI (five patients; 2.28 +- 0.09 x 10-3 min-1) compared to those who experienced radiographic vasospasm only (three patients; 1.85 +- 0.12 x 10-3 min-1; p &lt; 0.05), or no vasospasm/ischemia (eight patients; 1.74 +- 0.07 x 10-3 min-1; p &lt; 0.01).	dci	114-117	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
29611451-4	2018	Ktrans &gt; 2 x 10-3 min-1 predicted development of DCI (AUC = 0.98, 95% CI: 0.93-1).	dci	52-55	CD59 molecule (CD59 blood group)	Homo sapiens	21-26
29567193-4	2018	The analyte solution was injected with an injection valve (2 muL volume) and a ternary solution of water/acetonitrile/ethyl acetate (3:8:2 vol ratio) was delivered as the eluent to the capillary tube at a flow rate of 8.6 muL min-1.	Water	99-104	CD59 molecule (CD59 blood group)	Homo sapiens	226-231
29559298-5	2018	CO became the dominant gas both on a mass and volume basis, at the heating rate of 350  C min-1 for all samples except xylan, which also produced a significant yield of CO2 (20.3 wt% and 25.4 vol%) compared to the other samples.	Carbon Monoxide	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	90-95
29548770-11	2018	Fat oxidation was lower post-exercise in SDS vs ORS (0.38+-0.1 vs 0.47+-0.2 g min-1, respectively; P=0.049).	Sodium Dodecyl Sulfate	41-44	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
29851229-9	2018	Their mean VO2 max in GXT and O2 uptake at the end of the 6MWT were 34 4 ml kg-1 min-1 (SD +- 7 6) and 27 2  ml kg-1 min-1 (SD +- 6 5), respectively.	Oxygen	12-14	CD59 molecule (CD59 blood group)	Homo sapiens	81-97
29851229-9	2018	Their mean VO2 max in GXT and O2 uptake at the end of the 6MWT were 34 4 ml kg-1 min-1 (SD +- 7 6) and 27 2  ml kg-1 min-1 (SD +- 6 5), respectively.	Oxygen	12-14	CD59 molecule (CD59 blood group)	Homo sapiens	117-133
29881309-8	2018	Results: Vitamin K antagonist use was associated with an extra change in renal function of -0.09 (95% CI -1.32 to 1.13) mL/min/1.73 m2 per year after adjustment for confounding.	Vitamin K	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
29861443-1	2018	A high extrusion ratio of 166:1 was applied to commercial AZ61 alloy in one step with an extrusion speed of 2.1 m min-1.	az61 alloy	58-68	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
29802330-6	2018	The highest degradation rate was found to be 9.66 x 10-6 min-1, achieved by the sample grown at 700  C for 5 min, which was 62% higher than the sample just treated at that temperature without graphene growth.	Graphite	192-200	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
29772810-5	2018	We find that locally enriched and immobilized CD59 presents obstacles to the diffusion of fluorescently labeled lipids with a different phase-partitioning behavior independent of cell cholesterol levels and type of lipid.	Cholesterol	184-195	CD59 molecule (CD59 blood group)	Homo sapiens	46-50
29486169-9	2018	The highest V O2 achieved at 115%, 130%, and 170% of iV O2max was 54.2 +- 7.9 mL kg-1 min-1, 52.5 +- 8.1 mL kg-1 min-1, and 49.6 +- 7.5 mL kg-1 min-1, respectively.	Oxygen	14-16	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
29771966-12	2018	Furthermore, the maximum carbon dioxide production increased under SB by ~4.8% (from ~3604 mL min-1 to ~3776 mL min-1, p = 0.049).	Carbon Dioxide	25-39	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
29771966-12	2018	Furthermore, the maximum carbon dioxide production increased under SB by ~4.8% (from ~3604 mL min-1 to ~3776 mL min-1, p = 0.049).	Carbon Dioxide	25-39	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
29771966-12	2018	Furthermore, the maximum carbon dioxide production increased under SB by ~4.8% (from ~3604 mL min-1 to ~3776 mL min-1, p = 0.049).	Sodium Bicarbonate	67-69	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
29771966-12	2018	Furthermore, the maximum carbon dioxide production increased under SB by ~4.8% (from ~3604 mL min-1 to ~3776 mL min-1, p = 0.049).	Sodium Bicarbonate	67-69	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
29486169-9	2018	The highest V O2 achieved at 115%, 130%, and 170% of iV O2max was 54.2 +- 7.9 mL kg-1 min-1, 52.5 +- 8.1 mL kg-1 min-1, and 49.6 +- 7.5 mL kg-1 min-1, respectively.	Oxygen	14-16	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
29486169-9	2018	The highest V O2 achieved at 115%, 130%, and 170% of iV O2max was 54.2 +- 7.9 mL kg-1 min-1, 52.5 +- 8.1 mL kg-1 min-1, and 49.6 +- 7.5 mL kg-1 min-1, respectively.	Oxygen	14-16	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
29501199-6	2018	Comparing with free ALT in solution (Vmax of free enzyme = 0.6 mM min-1), the resultant enzyme reactor has exhibited good reusability and stability, and displayed about five times enhanced enzymolysis efficiency with L-alanine as the substrate (Vmax of enzyme reactor = 3.4 mM min-1).	Alanine	217-226	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
29501199-6	2018	Comparing with free ALT in solution (Vmax of free enzyme = 0.6 mM min-1), the resultant enzyme reactor has exhibited good reusability and stability, and displayed about five times enhanced enzymolysis efficiency with L-alanine as the substrate (Vmax of enzyme reactor = 3.4 mM min-1).	Alanine	217-226	CD59 molecule (CD59 blood group)	Homo sapiens	277-282
29888026-2	2018	Chromatographic separation was attained on an ACQUITY UPLC  BEH C18 column (100 mm x 2.1 mm, 1.7 mum) with a mobile phase consisting of 20 mM phosphate buffer (pH 7.0) : acetonitrile in the proportion (60 : 40 v/v) isocratically pumped at a flow rate of 1.25 mL min-1, and detection was monitored at 305 nm.	acetonitrile	170-182	CD59 molecule (CD59 blood group)	Homo sapiens	262-267
29505165-7	2018	The detection limit of PST-NA to O2.- was estimated to be 2.1 nm min-1 over 60 min of detection.	Superoxides	33-35	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
29581232-5	2018	For example, in HeLa cells, GlcNAc treatment, which increases glycan branching, increased major histocompatibility complex class I (MHCI) internalization but inhibited CIE of the glycoprotein CD59 molecule (CD59).	2-acetamido-2-deoxy-4-O-(beta-2-acetamid-2-deoxyglucopyranosyl)glucopyranose	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	192-196
29581232-5	2018	For example, in HeLa cells, GlcNAc treatment, which increases glycan branching, increased major histocompatibility complex class I (MHCI) internalization but inhibited CIE of the glycoprotein CD59 molecule (CD59).	2-acetamido-2-deoxy-4-O-(beta-2-acetamid-2-deoxyglucopyranosyl)glucopyranose	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	207-211
29581232-6	2018	The effects of knocking down the expression of galectin 3, a carbohydrate-binding protein and an important player in galectin-glycan interactions, were also cargo-specific and stimulated CD59 uptake.	Polysaccharides	126-132	CD59 molecule (CD59 blood group)	Homo sapiens	187-191
29581232-7	2018	By contrast, inhibition of all galectin-glycan interactions by lactose inhibited CIE of both MHCI and CD59.	Polysaccharides	40-46	CD59 molecule (CD59 blood group)	Homo sapiens	102-106
29581232-7	2018	By contrast, inhibition of all galectin-glycan interactions by lactose inhibited CIE of both MHCI and CD59.	Lactose	63-70	CD59 molecule (CD59 blood group)	Homo sapiens	102-106
29581232-7	2018	By contrast, inhibition of all galectin-glycan interactions by lactose inhibited CIE of both MHCI and CD59.	chlorimuron ethyl	81-84	CD59 molecule (CD59 blood group)	Homo sapiens	102-106
29477929-4	2018	Optimal conditions with potential for applicability under GMP conditions were found at a mobile phase flow rate of 1.0 mL min-1 by using a pneumatic micro-flow LC nebulizer mounted onto a Peltier-cooled cyclonic spray chamber cooled to -1  C for sample introduction.	guanosine 5'-monophosphorothioate	58-61	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
29661378-3	2018	METHODS: In this randomised, double blind, placebo-controlled crossover study, healthy volunteers were treated with sodium nitroprusside 0.5 mug kg-1 min-1 or placebo during administration of escalating doses of RS-ketamine (total dose 140 mg) or esketamine (70 mg).	Nitroprusside	116-136	CD59 molecule (CD59 blood group)	Homo sapiens	150-155
29997875-9	2018	For example, aerobic oxidation of 4-tert-butylbenzaldehyde to 4-tert-butylbenzoic acid was achieved at a rate of 10.5 mg min-1 with an isolated product yield of 66%.	4-tert-Butylbenzaldehyde	34-58	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
29997875-9	2018	For example, aerobic oxidation of 4-tert-butylbenzaldehyde to 4-tert-butylbenzoic acid was achieved at a rate of 10.5 mg min-1 with an isolated product yield of 66%.	4-tert-butylbenzoic acid	62-86	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
29661389-5	2018	RESULTS: Remifentanil reduced isohypercapnic ventilation (end-tidal PCO2 6.5 kPa) by approximately 40% (from 20 to 12 litre min-1) in esketamine and placebo arms of the study, through an effect on baseline ventilation and ventilatory CO2 sensitivity.	Remifentanil	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
29484572-11	2018	CONCLUSION: Low-dose Sofosbuvir and full-dose Daclatasvir are safe and effective in treating CHC in patients with CKD with eGFR less than 30 mL/min/1.73 m2.	daclatasvir	46-57	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
29484572-11	2018	CONCLUSION: Low-dose Sofosbuvir and full-dose Daclatasvir are safe and effective in treating CHC in patients with CKD with eGFR less than 30 mL/min/1.73 m2.	Sofosbuvir	21-31	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
29725363-6	2018	In addition, a significant association was revealed between the location of CBP/PAG and CD59, which were co-expressed in the same region of the cell membrane, implicating a potential overlap of the elicited signaling pathways.	phenylacetylglycine	80-83	CD59 molecule (CD59 blood group)	Homo sapiens	88-92
29407867-3	2018	Complex 1 catalyzes H2O2 disproportionation with second-order rate constant kcat = 305(9) M-1 min-1 and without a time-lag phase.	Hydrogen Peroxide	20-24	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
28758835-6	2018	Rate of oxygen consumption decreased by 10% from IS to SS (IS: 37.9 +- 5.68 ml kg-1 min-1, SS: 34.1 +- 5.07 ml kg-1 min-1, P &lt; 0.0001, ES 3.05).	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
29611289-6	2018	The results show that the apparent kinetic rate constant of catalytic reduction of 4-nitrophenol (4-NP) in water by reductant sodium borohydride (NaBH4 ), is ranging from 3.7 to 37.9 min-1 at temperatures from 20 to 45 oC and the molar ratio of NaBH4 to 4-NP from 100:1 to 500:1.	4-nitrophenol	83-96	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
29611289-6	2018	The results show that the apparent kinetic rate constant of catalytic reduction of 4-nitrophenol (4-NP) in water by reductant sodium borohydride (NaBH4 ), is ranging from 3.7 to 37.9 min-1 at temperatures from 20 to 45 oC and the molar ratio of NaBH4 to 4-NP from 100:1 to 500:1.	4-nitrophenol	98-102	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
29611289-6	2018	The results show that the apparent kinetic rate constant of catalytic reduction of 4-nitrophenol (4-NP) in water by reductant sodium borohydride (NaBH4 ), is ranging from 3.7 to 37.9 min-1 at temperatures from 20 to 45 oC and the molar ratio of NaBH4 to 4-NP from 100:1 to 500:1.	Water	107-112	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
29611289-6	2018	The results show that the apparent kinetic rate constant of catalytic reduction of 4-nitrophenol (4-NP) in water by reductant sodium borohydride (NaBH4 ), is ranging from 3.7 to 37.9 min-1 at temperatures from 20 to 45 oC and the molar ratio of NaBH4 to 4-NP from 100:1 to 500:1.	sodium borohydride	126-144	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
29611289-6	2018	The results show that the apparent kinetic rate constant of catalytic reduction of 4-nitrophenol (4-NP) in water by reductant sodium borohydride (NaBH4 ), is ranging from 3.7 to 37.9 min-1 at temperatures from 20 to 45 oC and the molar ratio of NaBH4 to 4-NP from 100:1 to 500:1.	sodium borohydride	146-151	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
29611289-6	2018	The results show that the apparent kinetic rate constant of catalytic reduction of 4-nitrophenol (4-NP) in water by reductant sodium borohydride (NaBH4 ), is ranging from 3.7 to 37.9 min-1 at temperatures from 20 to 45 oC and the molar ratio of NaBH4 to 4-NP from 100:1 to 500:1.	sodium borohydride	245-250	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
29611289-6	2018	The results show that the apparent kinetic rate constant of catalytic reduction of 4-nitrophenol (4-NP) in water by reductant sodium borohydride (NaBH4 ), is ranging from 3.7 to 37.9 min-1 at temperatures from 20 to 45 oC and the molar ratio of NaBH4 to 4-NP from 100:1 to 500:1.	4-nitrophenol	254-258	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
29408130-4	2018	The as-prepared Pt@h-mNSiO2 catalyst exhibited superior activity for hydrogen generation from the hydrolysis of ammonia borane, with a turnover frequency of 371.7 molH2 mol-1Pt min-1 at ambient temperature, probably owing to the abundant mesopores and high surface area, leading to a considerable increase in the accessible active sites.	Hydrogen	69-77	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
29408130-4	2018	The as-prepared Pt@h-mNSiO2 catalyst exhibited superior activity for hydrogen generation from the hydrolysis of ammonia borane, with a turnover frequency of 371.7 molH2 mol-1Pt min-1 at ambient temperature, probably owing to the abundant mesopores and high surface area, leading to a considerable increase in the accessible active sites.	Ammonia borane	112-126	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
29627804-11	2018	RESULTS: In the subgroup with eGFR &lt;60 mL/min/1.73 m2, the Harrell"s c of unadjusted total calcium (0.801) was significantly larger than those of the local formulas (0.790, p=0.002) and the best formula taken from literature (0.791, p=0.004).	Calcium	94-101	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
29765683-6	2018	Based on the Cu-ZSM-5 catalyst with Cu loading of 6 wt%, complete removal of phenol and a high TOC reduction (around 70%) have been achieved at the temperature of 80 C feed flow rate of 2 ml min-1 and catalyst bed height of 3 cm.	Copper	13-15	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
29413996-4	2018	Maximum bio-oil yield of 38.1 wt% was obtained at pyrolysis temperature of 550  C, heating rate of 20  C min-1 and nitrogen flow rate of 226 mL min-1.	Bio-Oil	8-15	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
29413996-4	2018	Maximum bio-oil yield of 38.1 wt% was obtained at pyrolysis temperature of 550  C, heating rate of 20  C min-1 and nitrogen flow rate of 226 mL min-1.	Bio-Oil	8-15	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
29413996-4	2018	Maximum bio-oil yield of 38.1 wt% was obtained at pyrolysis temperature of 550  C, heating rate of 20  C min-1 and nitrogen flow rate of 226 mL min-1.	Nitrogen	115-123	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
29316267-10	2018	Median heart rate increased by 10/min 1 and 4 h after digoxin-Fab.	digoxin-fab	54-65	CD59 molecule (CD59 blood group)	Homo sapiens	34-47
29408085-10	2018	A high As (III) removal efficiency (91.6%) was obtained at an initial As (III) concentration of 5 mg L-1 at a flow rate of 1 mL min-1.	as (iii)	7-15	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
29332011-2	2018	This is most applicable to older individuals with CKD, the majority of whom have a creatinine-based estimated glomerular filtration rate (eGFR) of 45-59 mL/min/1.73 m2 (CKD stage 3a).	Creatinine	83-93	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
29606257-6	2018	Median estimated glomerular filtration rate was 31mL/min 1 month and 38mL/min 3 months after ifosfamide infusion, versus 67mL/min at baseline.	Ifosfamide	93-103	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
29504254-6	2018	Insulin sensitivity in the vitamin D group improved (from 4.6 +- 2.0 to 6.9 +- 3.3 mg kg-1  min-1 ; P &lt; 0.001), whereas no changes were observed in the placebo group (from 4.9 +- 1.1 to 5.1 +- 0.3 mg kg-1  min-1 ; P = 0.84).	Vitamin D	27-36	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
29504254-6	2018	Insulin sensitivity in the vitamin D group improved (from 4.6 +- 2.0 to 6.9 +- 3.3 mg kg-1  min-1 ; P &lt; 0.001), whereas no changes were observed in the placebo group (from 4.9 +- 1.1 to 5.1 +- 0.3 mg kg-1  min-1 ; P = 0.84).	Vitamin D	27-36	CD59 molecule (CD59 blood group)	Homo sapiens	209-214
29541246-1	2018	Cluster of differentiation 59 (CD59) is a glycosylphosphatidylinositol-anchored protein.	Glycosylphosphatidylinositols	42-70	CD59 molecule (CD59 blood group)	Homo sapiens	31-35
29541246-8	2018	The results also indicated that CD59 may transfer the palmitate group from phosphatidylinositol to LAT to form LAT palmitate, which then localizes to lipid rafts to regulate T-cell activation.	Palmitates	54-63	CD59 molecule (CD59 blood group)	Homo sapiens	32-36
29541246-8	2018	The results also indicated that CD59 may transfer the palmitate group from phosphatidylinositol to LAT to form LAT palmitate, which then localizes to lipid rafts to regulate T-cell activation.	Phosphatidylinositols	75-95	CD59 molecule (CD59 blood group)	Homo sapiens	32-36
29661427-9	2018	Pretreatment, intra-treatment, and post-treatment creatinine clearances were 61.4, 60.6, and 60.7 mL/min/1.73 m2, respectively (not significant [NS]).	Creatinine	50-60	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
29441620-4	2018	As a result, the turnover number for CO production reaches a high value of 678 with an unprecedented turnover frequency of 3.77 min-1 , superior to those obtained with the state-of-the-art heterogeneous photocatalysts.	Carbon Monoxide	37-39	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
29132945-8	2018	After adjustment for demographic, cardiovascular, and kidney-specific covariates, higher uric acid concentrations were independently associated with risk for kidney failure in participants with estimated glomerular filtration rates (eGFRs) &gt;= 45mL/min/1.73m2 (adjusted HR per 1-standard deviation greater baseline uric acid, 1.40; 95% CI, 1.12-1.75), but not in those with eGFRs&lt;30mL/min/1.73m2.	Uric Acid	89-98	CD59 molecule (CD59 blood group)	Homo sapiens	251-256
29132945-8	2018	After adjustment for demographic, cardiovascular, and kidney-specific covariates, higher uric acid concentrations were independently associated with risk for kidney failure in participants with estimated glomerular filtration rates (eGFRs) &gt;= 45mL/min/1.73m2 (adjusted HR per 1-standard deviation greater baseline uric acid, 1.40; 95% CI, 1.12-1.75), but not in those with eGFRs&lt;30mL/min/1.73m2.	Uric Acid	89-98	CD59 molecule (CD59 blood group)	Homo sapiens	390-395
29232640-5	2018	At initial IBP concentration of 1 mg L-1, complete removal of IBP with reaction rate of 1.7 x 10-1 min-1 was happened within a short reaction time of 30 min.	Ibuprofen	11-14	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
29232640-5	2018	At initial IBP concentration of 1 mg L-1, complete removal of IBP with reaction rate of 1.7 x 10-1 min-1 was happened within a short reaction time of 30 min.	Ibuprofen	62-65	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
29260481-8	2018	The photodegradation rate was 0.114 min-1 when the concentration of norfloxacin was 1 mg L-1.	Norfloxacin	68-79	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
29507732-7	2018	Results: Linear mixed models showed that the maximal oxygen uptake increased by 1.1 mL kg-1 min- 1 during the rehabilitation program and by 3.7 mL kg-1 min- 1 at one-year follow-up.	Oxygen	53-59	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
29314596-12	2018	Of the patients, 95% were found to be sensitive to ASA, with values under the threshold of normality (400 AU min-1 ).	Aspirin	51-54	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
28626998-7	2018	Pharmacokinetic analysis of the patients" data acquired by LaBBI showed that Ktrans was higher in fibrous tissue (0.0717 +- 0.0279 min-1 ), while lower in necrotic core (0.0206 +- 0.0040 min-1 ) and intraplaque hemorrhage (0.0078 +- 0.0007 min-1 ), compared with normal vessel wall (0.0273 +- 0.0052 min-1 ).	ktrans	77-83	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
28626998-7	2018	Pharmacokinetic analysis of the patients" data acquired by LaBBI showed that Ktrans was higher in fibrous tissue (0.0717 +- 0.0279 min-1 ), while lower in necrotic core (0.0206 +- 0.0040 min-1 ) and intraplaque hemorrhage (0.0078 +- 0.0007 min-1 ), compared with normal vessel wall (0.0273 +- 0.0052 min-1 ).	ktrans	77-83	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
28626998-7	2018	Pharmacokinetic analysis of the patients" data acquired by LaBBI showed that Ktrans was higher in fibrous tissue (0.0717 +- 0.0279 min-1 ), while lower in necrotic core (0.0206 +- 0.0040 min-1 ) and intraplaque hemorrhage (0.0078 +- 0.0007 min-1 ), compared with normal vessel wall (0.0273 +- 0.0052 min-1 ).	ktrans	77-83	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
28626998-7	2018	Pharmacokinetic analysis of the patients" data acquired by LaBBI showed that Ktrans was higher in fibrous tissue (0.0717 +- 0.0279 min-1 ), while lower in necrotic core (0.0206 +- 0.0040 min-1 ) and intraplaque hemorrhage (0.0078 +- 0.0007 min-1 ), compared with normal vessel wall (0.0273 +- 0.0052 min-1 ).	ktrans	77-83	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
29507732-7	2018	Results: Linear mixed models showed that the maximal oxygen uptake increased by 1.1 mL kg-1 min- 1 during the rehabilitation program and by 3.7 mL kg-1 min- 1 at one-year follow-up.	Oxygen	53-59	CD59 molecule (CD59 blood group)	Homo sapiens	152-158
29515957-6	2018	The photocatalytic efficiency of phenol and toluene degradation under vis irradiation in the presence of 0.25% Nd-TiO2(HT) reached 0.62 and 3.36 mumol dm-1 min-1, respectively.	Phenol	33-39	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
29378400-3	2018	By precisely controlling their parts per million level concentrations, centimeter-sized single-crystal graphene is obtained in a reliable manner with a maximum growth rate up to 190 mum min-1.	Graphite	103-111	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
29515957-6	2018	The photocatalytic efficiency of phenol and toluene degradation under vis irradiation in the presence of 0.25% Nd-TiO2(HT) reached 0.62 and 3.36 mumol dm-1 min-1, respectively.	Toluene	44-51	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
29515957-6	2018	The photocatalytic efficiency of phenol and toluene degradation under vis irradiation in the presence of 0.25% Nd-TiO2(HT) reached 0.62 and 3.36 mumol dm-1 min-1, respectively.	nd-tio2	111-118	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
28899601-5	2018	We recommend reducing the baclofen dose in patients who have moderately reduced kidney function (estimated glomerular filtration rate, 30-60mL/min/1.73m2) and avoiding use in patients with severely reduced kidney function (estimated glomerular filtration rate &lt; 30mL/min/1.73m2) or on renal replacement therapy.	Baclofen	26-34	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
28899601-5	2018	We recommend reducing the baclofen dose in patients who have moderately reduced kidney function (estimated glomerular filtration rate, 30-60mL/min/1.73m2) and avoiding use in patients with severely reduced kidney function (estimated glomerular filtration rate &lt; 30mL/min/1.73m2) or on renal replacement therapy.	Baclofen	26-34	CD59 molecule (CD59 blood group)	Homo sapiens	270-275
29406176-9	2018	The median weight and anaesthesia duration-adjusted dose of norepinephrine were 0.11 (0.00-0.45) ng kg-1 min-1 and 0.00 (0.00-0.00) kg-1 min-1 in the normal-saline and balanced-crystalloid groups, respectively (P=0.003).	Norepinephrine	60-74	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
29030339-6	2018	Tyramine reduced LVC in both groups at 10-W exercise (COPD: -3 +- 1 ml min-1 mmHg-1 and controls: -3 +- 1 ml min-1 mmHg-1, P &lt; 0.05) and 20% WLmax (COPD: -4 +- 1 ml min-1 mmHg-1 and controls: -3 +- 1 ml min-1 mmHg-1, P &lt; 0.05) with no difference between groups.	Tyramine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
29030339-6	2018	Tyramine reduced LVC in both groups at 10-W exercise (COPD: -3 +- 1 ml min-1 mmHg-1 and controls: -3 +- 1 ml min-1 mmHg-1, P &lt; 0.05) and 20% WLmax (COPD: -4 +- 1 ml min-1 mmHg-1 and controls: -3 +- 1 ml min-1 mmHg-1, P &lt; 0.05) with no difference between groups.	Tyramine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
29030339-6	2018	Tyramine reduced LVC in both groups at 10-W exercise (COPD: -3 +- 1 ml min-1 mmHg-1 and controls: -3 +- 1 ml min-1 mmHg-1, P &lt; 0.05) and 20% WLmax (COPD: -4 +- 1 ml min-1 mmHg-1 and controls: -3 +- 1 ml min-1 mmHg-1, P &lt; 0.05) with no difference between groups.	Tyramine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
29030339-6	2018	Tyramine reduced LVC in both groups at 10-W exercise (COPD: -3 +- 1 ml min-1 mmHg-1 and controls: -3 +- 1 ml min-1 mmHg-1, P &lt; 0.05) and 20% WLmax (COPD: -4 +- 1 ml min-1 mmHg-1 and controls: -3 +- 1 ml min-1 mmHg-1, P &lt; 0.05) with no difference between groups.	Tyramine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
28962537-13	2018	Dose reductions of ~30% for creatinine clearance &lt;=30 mL/min/1.73 m2 are required.	Creatinine	28-38	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
29248594-11	2018	Overexpression of LST-3TM12 was associated with enhanced cellular accumulation of dehydroepiandrosterone sulfate (Vmax 300.2 pmol mg-1 min-1; Km 34.2 microm) and estradiol 17beta-glucuronide (Vmax 29.9 mol mg-1 min-1 and Km 32.8 microM).	Dehydroepiandrosterone Sulfate	82-112	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
29138287-5	2018	UGT2B7 and UGT2B17 exhibited the greatest level of clopidogrel carboxylic acid glucuronidation activities, with a CLint,u of 2.42 and 2.82 microl min-1 mg-1, respectively.	clopidogrel carboxylic acid	51-78	CD59 molecule (CD59 blood group)	Homo sapiens	146-156
29152797-11	2018	During moderate exercise, sweat rate was attenuated at the l-NAME and Ascorbate + l-NAME sites (both ~1.0 mg min-1  cm-2 ; all P &lt; 0.05) but not at the Ascorbate site (~1.1 mg min-1  cm-2 ; both P &gt;= 0.28) in comparison to the Control site (~1.1 mg min-1  cm-2 ).	Ascorbic Acid	70-79	CD59 molecule (CD59 blood group)	Homo sapiens	109-120
29675226-4	2018	Of several such M2+-free DNAymes, DNAzyme 7-38-32 cleaves a 19 nt all-RNA substrate with multiple-turnover, under simulated physiological conditions wherein only 0.5 mM Mg2+ was present, attaining values of kcat of 1.06 min-1 and a KM of 1.37 muM corresponding to a catalytic efficiency of ~106 M-1 min-1.	magnesium ion	169-173	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
29675226-4	2018	Of several such M2+-free DNAymes, DNAzyme 7-38-32 cleaves a 19 nt all-RNA substrate with multiple-turnover, under simulated physiological conditions wherein only 0.5 mM Mg2+ was present, attaining values of kcat of 1.06 min-1 and a KM of 1.37 muM corresponding to a catalytic efficiency of ~106 M-1 min-1.	magnesium ion	169-173	CD59 molecule (CD59 blood group)	Homo sapiens	299-304
29103517-8	2018	Cs alone enhanced CD59 expression more potently than either pCSM or CsM.	Cesium	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	18-22
29965683-5	2018	The Freundlich isotherm showed that activated carbon had better adsorption properties for NH4+-N, TP, and permanganate index in water.When the disk speed was 3 r min-1, the removal efficiency was the best, and the removal rates of NH4+-N, TP and permanganate index were the best at 86.05%, 81.28%, and 77.09%, respectively.	Carbon	46-52	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
29300298-4	2018	A highly dispersed Ni/SiO2 catalyst prepared by the direct reduction of Ni(NO3)2/SiO2 suppressed the condensation reactions by promoting the hydrogenation of adsorbed imines, and it gave the improved hydrogenation activity of 0.63 mol kgcat-1 min-1 and primary amine selectivity of 94% when NaOH was added into the reactor.	Silicon Dioxide	22-26	CD59 molecule (CD59 blood group)	Homo sapiens	243-248
29300298-4	2018	A highly dispersed Ni/SiO2 catalyst prepared by the direct reduction of Ni(NO3)2/SiO2 suppressed the condensation reactions by promoting the hydrogenation of adsorbed imines, and it gave the improved hydrogenation activity of 0.63 mol kgcat-1 min-1 and primary amine selectivity of 94% when NaOH was added into the reactor.	ni(no3)2	72-80	CD59 molecule (CD59 blood group)	Homo sapiens	243-248
29300298-4	2018	A highly dispersed Ni/SiO2 catalyst prepared by the direct reduction of Ni(NO3)2/SiO2 suppressed the condensation reactions by promoting the hydrogenation of adsorbed imines, and it gave the improved hydrogenation activity of 0.63 mol kgcat-1 min-1 and primary amine selectivity of 94% when NaOH was added into the reactor.	Silicon Dioxide	81-85	CD59 molecule (CD59 blood group)	Homo sapiens	243-248
29300298-4	2018	A highly dispersed Ni/SiO2 catalyst prepared by the direct reduction of Ni(NO3)2/SiO2 suppressed the condensation reactions by promoting the hydrogenation of adsorbed imines, and it gave the improved hydrogenation activity of 0.63 mol kgcat-1 min-1 and primary amine selectivity of 94% when NaOH was added into the reactor.	Imines	167-173	CD59 molecule (CD59 blood group)	Homo sapiens	243-248
29300298-4	2018	A highly dispersed Ni/SiO2 catalyst prepared by the direct reduction of Ni(NO3)2/SiO2 suppressed the condensation reactions by promoting the hydrogenation of adsorbed imines, and it gave the improved hydrogenation activity of 0.63 mol kgcat-1 min-1 and primary amine selectivity of 94% when NaOH was added into the reactor.	Amines	261-266	CD59 molecule (CD59 blood group)	Homo sapiens	243-248
29300298-4	2018	A highly dispersed Ni/SiO2 catalyst prepared by the direct reduction of Ni(NO3)2/SiO2 suppressed the condensation reactions by promoting the hydrogenation of adsorbed imines, and it gave the improved hydrogenation activity of 0.63 mol kgcat-1 min-1 and primary amine selectivity of 94% when NaOH was added into the reactor.	Sodium Hydroxide	291-295	CD59 molecule (CD59 blood group)	Homo sapiens	243-248
30484243-4	2018	We performed single fluorescent-molecule imaging and revealed that ganglioside probes dynamically enter and exit rafts containing CD59, a glycosylphosphatidylinositol (GPI)-anchored protein, both before and after stimulation.	Gangliosides	67-78	CD59 molecule (CD59 blood group)	Homo sapiens	130-134
30484243-4	2018	We performed single fluorescent-molecule imaging and revealed that ganglioside probes dynamically enter and exit rafts containing CD59, a glycosylphosphatidylinositol (GPI)-anchored protein, both before and after stimulation.	Glycosylphosphatidylinositols	138-166	CD59 molecule (CD59 blood group)	Homo sapiens	130-134
30484243-4	2018	We performed single fluorescent-molecule imaging and revealed that ganglioside probes dynamically enter and exit rafts containing CD59, a glycosylphosphatidylinositol (GPI)-anchored protein, both before and after stimulation.	Glycosylphosphatidylinositols	168-171	CD59 molecule (CD59 blood group)	Homo sapiens	130-134
30484243-5	2018	The residency time of our ganglioside probes in CD59 oligomers was 48 ms after stimulation.	Gangliosides	26-37	CD59 molecule (CD59 blood group)	Homo sapiens	48-52
30484243-8	2018	Furthermore, they demonstrate that gangliosides continually move in and out of rafts that contain CD59 in an extremely dynamic manner and at a much higher frequency than expected.	Gangliosides	35-47	CD59 molecule (CD59 blood group)	Homo sapiens	98-102
30080325-2	2018	A deficiency of vitamin D was significantly more prevalent in COPD patients with GFRcys &lt;60 ml/min/1,73 m2 compared to patients with preserved renal function.	Vitamin D	16-25	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
29287673-5	2018	The primary outcome measure of our study was the time taken to achieve EtO2&gt;=90% at 5 and 10L.min-1 flow rates.	eto2	71-75	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
29287673-6	2018	RESULTS: At oxygen flow rate of 5L.min-1, time to reach EtO2&gt;=90% was significantly longer with Bain"s system (3.7+-0.67min) than Mapleson A and Circle system (2.9+-0.6, 3.3+-0.97min, respectively).	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
29287673-6	2018	RESULTS: At oxygen flow rate of 5L.min-1, time to reach EtO2&gt;=90% was significantly longer with Bain"s system (3.7+-0.67min) than Mapleson A and Circle system (2.9+-0.6, 3.3+-0.97min, respectively).	eto2	56-60	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
29287673-7	2018	However at oxygen flow rate of 10L.min-1 this time was significantly shorter and comparable among all the three breathing systems (2.33+-0.38min with Mapleson, 2.59+-0.50min with Bain"s and 2.60+-0.47min with Circle system).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
29287673-8	2018	CONCLUSIONS: With spontaneous normal tidal volume breathing at oxygen flow rate of 5L.min-1, Mapleson A can optimally preoxygenate patients within 3min while Bain"s and Circle system require more time.	Oxygen	63-69	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
29287673-8	2018	CONCLUSIONS: With spontaneous normal tidal volume breathing at oxygen flow rate of 5L.min-1, Mapleson A can optimally preoxygenate patients within 3min while Bain"s and Circle system require more time.	mapleson a	93-103	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
29287673-9	2018	However at O2 flow rate of 10L.min-1 all the three breathing systems are capable of optimally preoxygenating the patients in less than 3min.	Oxygen	11-13	CD59 molecule (CD59 blood group)	Homo sapiens	31-36
28834279-9	2018	The Km (app) and Vmax (app) values of norendoxifen formation from endoxifen in HLM was 47.8 mum and 35.39 pmol min-1 mg-1 .	N,N-didesmethyl-4-hydroxytamoxifen	38-50	CD59 molecule (CD59 blood group)	Homo sapiens	111-121
28834279-9	2018	The Km (app) and Vmax (app) values of norendoxifen formation from endoxifen in HLM was 47.8 mum and 35.39 pmol min-1 mg-1 .	4-hydroxy-N-desmethyltamoxifen	41-50	CD59 molecule (CD59 blood group)	Homo sapiens	111-121
27256921-7	2018	Mean plasma clearance (+-SD) for 51 Cr-EDTA was 59 7 +- 18 8 ml min-1 .	cr-edta	36-43	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
27256921-8	2018	The mean plasma clearance for mannitol ranged between 57 0 +- 20 1 and 61 1 +- 16 7 ml min-1 and Vd was 21 3 +- 6 2% per kg b.w.	Mannitol	30-38	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
29965683-5	2018	The Freundlich isotherm showed that activated carbon had better adsorption properties for NH4+-N, TP, and permanganate index in water.When the disk speed was 3 r min-1, the removal efficiency was the best, and the removal rates of NH4+-N, TP and permanganate index were the best at 86.05%, 81.28%, and 77.09%, respectively.	nh4+-n	90-96	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
29965683-5	2018	The Freundlich isotherm showed that activated carbon had better adsorption properties for NH4+-N, TP, and permanganate index in water.When the disk speed was 3 r min-1, the removal efficiency was the best, and the removal rates of NH4+-N, TP and permanganate index were the best at 86.05%, 81.28%, and 77.09%, respectively.	permanganic acid	106-118	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
29965683-5	2018	The Freundlich isotherm showed that activated carbon had better adsorption properties for NH4+-N, TP, and permanganate index in water.When the disk speed was 3 r min-1, the removal efficiency was the best, and the removal rates of NH4+-N, TP and permanganate index were the best at 86.05%, 81.28%, and 77.09%, respectively.	Water	128-133	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
29965683-5	2018	The Freundlich isotherm showed that activated carbon had better adsorption properties for NH4+-N, TP, and permanganate index in water.When the disk speed was 3 r min-1, the removal efficiency was the best, and the removal rates of NH4+-N, TP and permanganate index were the best at 86.05%, 81.28%, and 77.09%, respectively.	nh4+-n	231-237	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
29190340-6	2018	In response to insulin-induced hypoglycemia, endogenous glucose production did not change from before to 6 months (0.42 +- 0.08 vs 0.54 +- 0.07 mg kg-1 min-1) but improved after 18 months (0.84 +- 0.15 mg kg-1 min-1; P &lt; 0.05 vs before CGM), albeit remaining less than in controls (1.39 +- 0.11 mg kg-1 min-1; P &lt;= 0.01 vs all).	Glucose	56-63	CD59 molecule (CD59 blood group)	Homo sapiens	210-215
29034524-10	2018	Intravenous infusions of dopamine (3 mug kg-1  min-1 ) and placebo (saline) were administered on both study days, according to a single-blind randomized cross-over design.	Dopamine	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
29190340-6	2018	In response to insulin-induced hypoglycemia, endogenous glucose production did not change from before to 6 months (0.42 +- 0.08 vs 0.54 +- 0.07 mg kg-1 min-1) but improved after 18 months (0.84 +- 0.15 mg kg-1 min-1; P &lt; 0.05 vs before CGM), albeit remaining less than in controls (1.39 +- 0.11 mg kg-1 min-1; P &lt;= 0.01 vs all).	Glucose	56-63	CD59 molecule (CD59 blood group)	Homo sapiens	210-215
29306438-6	2018	Single-molecule tracking of fluorescent GM1 and GM3 revealed that these molecules are transiently and dynamically recruited to monomers (monomer-associated rafts) and homodimer rafts of the raftophilic GPI-anchored protein CD59 in quiescent cells, with exponential residency times of 12 and 40ms, respectively, in a manner dependent on raft-lipid interactions.	G(M1) Ganglioside	40-43	CD59 molecule (CD59 blood group)	Homo sapiens	223-227
28886372-10	2018	The adsorption kinetics also follow, both pseudo first order and intraparticle diffusion model with adsorption capacity of 84.91mg/g and intra particle diffusion rate constant of 10.53mg/g min1/2 for Bi2O3@GO nanocomposites.	bi2o3	200-205	CD59 molecule (CD59 blood group)	Homo sapiens	189-195
29306438-6	2018	Single-molecule tracking of fluorescent GM1 and GM3 revealed that these molecules are transiently and dynamically recruited to monomers (monomer-associated rafts) and homodimer rafts of the raftophilic GPI-anchored protein CD59 in quiescent cells, with exponential residency times of 12 and 40ms, respectively, in a manner dependent on raft-lipid interactions.	gm3	48-51	CD59 molecule (CD59 blood group)	Homo sapiens	223-227
29306438-7	2018	Upon CD59 stimulation, which induces CD59-cluster signaling rafts, the fluorescent GM1 and GM3 analogs were recruited to the signaling rafts, with a lifetime of 48ms.	G(M1) Ganglioside	83-86	CD59 molecule (CD59 blood group)	Homo sapiens	5-9
29306438-7	2018	Upon CD59 stimulation, which induces CD59-cluster signaling rafts, the fluorescent GM1 and GM3 analogs were recruited to the signaling rafts, with a lifetime of 48ms.	G(M1) Ganglioside	83-86	CD59 molecule (CD59 blood group)	Homo sapiens	37-41
29306438-7	2018	Upon CD59 stimulation, which induces CD59-cluster signaling rafts, the fluorescent GM1 and GM3 analogs were recruited to the signaling rafts, with a lifetime of 48ms.	gm3	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	5-9
29306438-7	2018	Upon CD59 stimulation, which induces CD59-cluster signaling rafts, the fluorescent GM1 and GM3 analogs were recruited to the signaling rafts, with a lifetime of 48ms.	gm3	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	37-41
29306438-9	2018	Furthermore, they show that gangliosides continually move in and out of rafts that contain CD59 in an extremely dynamic manner, with much higher frequency than expected previously.	Gangliosides	28-40	CD59 molecule (CD59 blood group)	Homo sapiens	91-95
29125685-4	2018	Ethane condition gives a growth rate about four times faster than methane, achieving about 420 microm min-1 for the growth of sub-centimeter graphene single crystals at temperature about 1000  C. In addition, the temperature threshold to obtain graphene using ethane can be reduced to 750  C, lower than the general growth temperature threshold (about 1000  C) with methane on copper foil.	Ethane	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
29125685-4	2018	Ethane condition gives a growth rate about four times faster than methane, achieving about 420 microm min-1 for the growth of sub-centimeter graphene single crystals at temperature about 1000  C. In addition, the temperature threshold to obtain graphene using ethane can be reduced to 750  C, lower than the general growth temperature threshold (about 1000  C) with methane on copper foil.	Methane	66-73	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
29125685-4	2018	Ethane condition gives a growth rate about four times faster than methane, achieving about 420 microm min-1 for the growth of sub-centimeter graphene single crystals at temperature about 1000  C. In addition, the temperature threshold to obtain graphene using ethane can be reduced to 750  C, lower than the general growth temperature threshold (about 1000  C) with methane on copper foil.	Graphite	141-149	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
29125685-4	2018	Ethane condition gives a growth rate about four times faster than methane, achieving about 420 microm min-1 for the growth of sub-centimeter graphene single crystals at temperature about 1000  C. In addition, the temperature threshold to obtain graphene using ethane can be reduced to 750  C, lower than the general growth temperature threshold (about 1000  C) with methane on copper foil.	Graphite	245-253	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
29339995-8	2017	Midfielders (57.2 +- 3.1 ml1 kg-1 min1) and defenders (56.1 +- 5.1 ml1 kg-1 min1) had significantly higher values of maximal oxygen uptake (VO2max) than goalkeepers (47.9 +- 0.2 ml-1 kg-1 min-1) and strikers (49.8 +- 6.2 ml-1 kg-1 min-1).	Oxygen	125-131	CD59 molecule (CD59 blood group)	Homo sapiens	34-38
29339995-8	2017	Midfielders (57.2 +- 3.1 ml1 kg-1 min1) and defenders (56.1 +- 5.1 ml1 kg-1 min1) had significantly higher values of maximal oxygen uptake (VO2max) than goalkeepers (47.9 +- 0.2 ml-1 kg-1 min-1) and strikers (49.8 +- 6.2 ml-1 kg-1 min-1).	Oxygen	125-131	CD59 molecule (CD59 blood group)	Homo sapiens	76-80
29125685-4	2018	Ethane condition gives a growth rate about four times faster than methane, achieving about 420 microm min-1 for the growth of sub-centimeter graphene single crystals at temperature about 1000  C. In addition, the temperature threshold to obtain graphene using ethane can be reduced to 750  C, lower than the general growth temperature threshold (about 1000  C) with methane on copper foil.	Ethane	67-73	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
29125685-4	2018	Ethane condition gives a growth rate about four times faster than methane, achieving about 420 microm min-1 for the growth of sub-centimeter graphene single crystals at temperature about 1000  C. In addition, the temperature threshold to obtain graphene using ethane can be reduced to 750  C, lower than the general growth temperature threshold (about 1000  C) with methane on copper foil.	Methane	366-373	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
29125685-4	2018	Ethane condition gives a growth rate about four times faster than methane, achieving about 420 microm min-1 for the growth of sub-centimeter graphene single crystals at temperature about 1000  C. In addition, the temperature threshold to obtain graphene using ethane can be reduced to 750  C, lower than the general growth temperature threshold (about 1000  C) with methane on copper foil.	Copper	377-383	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
29435189-2	2018	The aim of this study was to evaluate the effect of continuous metformin treatment in patients with type 2 diabetes mellitus (DM) and moderate chronic kidney disease (CKD) (estimated glomerular filtration rate (eGFR) 30-0 ml/min/1.73 m2) on renal function.	Metformin	63-72	CD59 molecule (CD59 blood group)	Homo sapiens	225-230
29326602-6	2017	In terms of physical capacity, the IET showed that cavers had a maximum oxygen uptake (VO2max) of 2,248.7 +- 657.8 ml min-1 (i.e., 32.4 +- 6.4 ml kg-1 min-1), while anaerobic threshold (AT) occurred on average at 74.5% of VO2max.	Oxygen	72-78	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
28943429-8	2017	However, shear stress-induced CD59 expression was reduced when the F-actin stress fiber formation process was delayed by Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) or destroyed by cytochalasin D (Cyto D), while Jasplakinolide (JAS) reversed the expression of CD59 through promotion of F-actin polymerization and its stabilizing capacities.	glycyl-arginyl-glycyl-aspartyl-seryl-proline	121-144	CD59 molecule (CD59 blood group)	Homo sapiens	30-34
28943429-8	2017	However, shear stress-induced CD59 expression was reduced when the F-actin stress fiber formation process was delayed by Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) or destroyed by cytochalasin D (Cyto D), while Jasplakinolide (JAS) reversed the expression of CD59 through promotion of F-actin polymerization and its stabilizing capacities.	Cytochalasin D	170-184	CD59 molecule (CD59 blood group)	Homo sapiens	30-34
30108918-6	2018	By measuring the conjugate addition product formed by 14 and GSH, we obtained a reaction rate constant of 302.5 x 10-3 min-1, which is about 30-fold higher than that of osimertinib.	Glutathione	61-64	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
28943429-8	2017	However, shear stress-induced CD59 expression was reduced when the F-actin stress fiber formation process was delayed by Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) or destroyed by cytochalasin D (Cyto D), while Jasplakinolide (JAS) reversed the expression of CD59 through promotion of F-actin polymerization and its stabilizing capacities.	jasplakinolide	201-215	CD59 molecule (CD59 blood group)	Homo sapiens	30-34
30108918-6	2018	By measuring the conjugate addition product formed by 14 and GSH, we obtained a reaction rate constant of 302.5 x 10-3 min-1, which is about 30-fold higher than that of osimertinib.	osimertinib	169-180	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
28943429-8	2017	However, shear stress-induced CD59 expression was reduced when the F-actin stress fiber formation process was delayed by Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) or destroyed by cytochalasin D (Cyto D), while Jasplakinolide (JAS) reversed the expression of CD59 through promotion of F-actin polymerization and its stabilizing capacities.	jasplakinolide	217-220	CD59 molecule (CD59 blood group)	Homo sapiens	30-34
29029015-6	2017	Oxycodone 20 mg had a significantly larger respiratory depressant effect than tapentadol 100 mg (mean difference -5.0 L min-1, 95% confidence interval: -7.1 to -2.9 L min-1, P&lt;0.01), but not larger than tapentadol 150 mg (oxycodone vs. tapentadol 150 mg: P&gt;0.05).	Oxycodone	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
28924724-4	2017	The device provided a 27.0 +- 2.2% reduction of metRBCs in a single pass at a flow rate of 77 muL min-1.	metrbcs	48-55	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
29225807-5	2017	Methods: In this pilot study, carbon dioxide (CO2) was used as the sole contrast agent to carry out renal angiography and RSDN in patients with moderate to severe CKD (eGFR 15-44 mL/min/1.73m2) and uncontrolled hypertension.	Carbon Dioxide	30-44	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
29225807-5	2017	Methods: In this pilot study, carbon dioxide (CO2) was used as the sole contrast agent to carry out renal angiography and RSDN in patients with moderate to severe CKD (eGFR 15-44 mL/min/1.73m2) and uncontrolled hypertension.	Carbon Dioxide	46-49	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
28164746-4	2017	Simulation based on batch column stripping experiments at 55 C at gas violent flow rates of 0.032 m3 m-2 min-1 indicated that ammonia concentrations could be reduced below inhibitory values in thermophilic food waste digestion for organic loading rates of up to 6 kg VS m-3 day-1.	Ammonia	126-133	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
28393327-6	2017	In a multiple regression analysis controlling for age and gender, we found a significant effect of duration of lithium treatment on estimated glomerular filtration rate (-0.85 ml/min/1.73 m2 per year of prior exposure).	Lithium	111-118	CD59 molecule (CD59 blood group)	Homo sapiens	179-184
27604107-6	2017	Patients undergoing adenosine stress showed a decrease in measured respiratory rate from initial to later scan phase measurements [12.4 (+-5.7) vs 5.6 (+-4.7) min-1, P &lt; .001] and tended to have a lower frequency of successful respiratory gating compared to dipyridamole (47% vs 71%, P = .12).	Adenosine	20-29	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
29238260-10	2017	Exercising heart rate was significantly higher (p = 0.05) in the salbutamol trial (183 +- 8 beats min-1) compared to control (180 +- 9 beats min-1) with a trend towards significance (p=0.06) in the placebo trial (179 +- 9 beats min-1) for the pooled groups, no differences were seen between trials in groups individually.	Albuterol	65-75	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
29238260-10	2017	Exercising heart rate was significantly higher (p = 0.05) in the salbutamol trial (183 +- 8 beats min-1) compared to control (180 +- 9 beats min-1) with a trend towards significance (p=0.06) in the placebo trial (179 +- 9 beats min-1) for the pooled groups, no differences were seen between trials in groups individually.	Albuterol	65-75	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
29238260-10	2017	Exercising heart rate was significantly higher (p = 0.05) in the salbutamol trial (183 +- 8 beats min-1) compared to control (180 +- 9 beats min-1) with a trend towards significance (p=0.06) in the placebo trial (179 +- 9 beats min-1) for the pooled groups, no differences were seen between trials in groups individually.	Albuterol	65-75	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
29097020-3	2017	RESULTS: Maximal oxygen consumption (ml kg min-1) was approximately 50% higher (p &lt; 0.05) in endurance-trained runners compared with sedentary controls (65.8 +- 2.3 and 43.1 +- 3.4, respectively).	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	43-48
29029015-6	2017	Oxycodone 20 mg had a significantly larger respiratory depressant effect than tapentadol 100 mg (mean difference -5.0 L min-1, 95% confidence interval: -7.1 to -2.9 L min-1, P&lt;0.01), but not larger than tapentadol 150 mg (oxycodone vs. tapentadol 150 mg: P&gt;0.05).	Oxycodone	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	167-172
29095953-9	2017	The mean differences in rate of decline in the estimated glomerular filtration rate (4.10 mL/min/1.73 m2 per year slower in uric acid-lowering therapy recipients, 95% CI, 1.86-6.35) and the standardized mean differences in the change in proteinuria or albuminuria (-0.23 units of standard deviation greater in uric acid-lowering therapy recipients; 95% CI, -0.43 to -0.04) were also statistically significant.	Uric Acid	124-133	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
28815695-0	2017	A distinctive histidine residue is essential for in vivo glycation-inactivation of human CD59 transgenically expressed in mice erythrocytes: Implications for human diabetes complications.	Histidine	14-23	CD59 molecule (CD59 blood group)	Homo sapiens	89-93
29047136-7	2017	The mean (SD) rate of ETCO2 increase was 0.17 (0.07) kPa.min-1 from an approximated baseline value of 5.00 kPa.	etco2	22-27	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
29047136-9	2017	This equates to a mean (SD) PV CO2 rise of 0.21 (0.08) kPa.min-1 during this period.	Carbon Dioxide	31-34	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
28838038-6	2017	Pal-IO showed a maximum Pb(II) adsorption capacity of 26.6 mg g-1 (experimental condition: 5 g L-1 adsorbent loading, 150 agitations min-1, initial Pb(II) concentration from 20 to 500 mg L-1, at 25  C) with easy separation of the spent adsorbent.	pal-io	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
28738204-6	2017	The second order rate constant for the reaction between sotalol and free available chlorine (FAC) was found to decrease from 60.1 to 39.1M-1min-1 when the pH was increased from 6 to 8.	Sotalol	56-63	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
28738204-6	2017	The second order rate constant for the reaction between sotalol and free available chlorine (FAC) was found to decrease from 60.1 to 39.1M-1min-1 when the pH was increased from 6 to 8.	Chlorine	83-91	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
28829688-9	2017	Blood lactate and HR were liable to daily fluctuations of 0.14-0.22 mmol L-1 and 4-5 beats min-1 respectively.	Lactic Acid	6-13	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
28841267-15	2017	Oxygen uptake was not different during the control and resistor trials (3.8 +- 0.9 versus 3.7 +- 0.8 l min-1 , P &gt; 0.05), but was lower on the proportional assist ventilator trial (3.4 +- 0.7 l min-1 , P &lt; 0.05) compared with control.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
28841267-15	2017	Oxygen uptake was not different during the control and resistor trials (3.8 +- 0.9 versus 3.7 +- 0.8 l min-1 , P &gt; 0.05), but was lower on the proportional assist ventilator trial (3.4 +- 0.7 l min-1 , P &lt; 0.05) compared with control.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	197-202
27977866-10	2017	Groups with flow rates at 1 and 0.5 mL min-1 had a significantly lower temperature rise when compared to the group without water flow (P &lt; 0.001).	Water	123-128	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
29170704-11	2017	The average VO2 for 50% CHO usage was significantly lower following M (0.84 +- 0.54 l min-1) than after P (1.21 +- 0.52 l min-1).	CAV protocol	24-27	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
28938439-7	2017	Interventions: Four experimental study days in randomized order with administration of either 1500 mg metformin or placebo in combination with intravenous infusion of cholecystokinin (0.4 pmol x kg-1 x min-1) or saline.	Cholecystokinin	167-182	CD59 molecule (CD59 blood group)	Homo sapiens	202-207
27832731-9	2017	The creatinine clearance of 77.3% of patients was below 60 mL/min/1.73 m2, 8.4% had proteinuria, and 2.5% had isolated microscopic hematuria.	Creatinine	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
29149950-6	2017	RESULTS: Creatinine clearance decreased from 94.3 +- 23 (t0) to 52.4 +- 22 mL/min/1.73 m2 (t0.1) and increased to 78.2 +- 19 mL/min/1.73 m2 after 10 years (t10).	Creatinine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
29149950-6	2017	RESULTS: Creatinine clearance decreased from 94.3 +- 23 (t0) to 52.4 +- 22 mL/min/1.73 m2 (t0.1) and increased to 78.2 +- 19 mL/min/1.73 m2 after 10 years (t10).	Creatinine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
29071494-5	2017	By dissolving ZnNRs substrate with an extremely low concentration of phosphoric acid (12.5 mM), up to 85.6% of the captured SKBR3 cells were released after reverse injection with flow rate of 100 muL min-1 for 15 min, which exhibited around 73.6% cell viability within 1 h after release to around 93.9% after re-cultured for 3 days.	znnrs	14-19	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
29071494-5	2017	By dissolving ZnNRs substrate with an extremely low concentration of phosphoric acid (12.5 mM), up to 85.6% of the captured SKBR3 cells were released after reverse injection with flow rate of 100 muL min-1 for 15 min, which exhibited around 73.6% cell viability within 1 h after release to around 93.9% after re-cultured for 3 days.	phosphoric acid	69-84	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
28837241-5	2017	It was found that the nanohybrid CoSx @POP catalyst exhibited a substantially enhanced catalytic performance of 1.07 mumol min-1 cm-2 , which is considered to be ca.	cosx	33-37	CD59 molecule (CD59 blood group)	Homo sapiens	123-133
29228713-2	2017	The LTQ Orbitrap LC-MS/MS mass spectrometry analysis of cell surface TF-Ag proteome of metastatic prostate cancer cells reveals that several cell surface glycoproteins expressing this carbohydrate antigen in prostate cancer (CD44, alpha2 integrin, beta1 integrin, CD49f, CD133, CD59, EphA2, CD138, transferrin receptor, profilin) are either known as stem cell markers or control important cancer stem-like cell functions.	Carbohydrates	184-196	CD59 molecule (CD59 blood group)	Homo sapiens	278-282
29051274-2	2017	During exercise at isotime, morphine decreased ventilation by 1.3+-0.5 L min-1 and breathing frequency by 2.0+-0.9 breaths min-1 (both p&lt;=0.041).	Morphine	28-36	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
29051274-2	2017	During exercise at isotime, morphine decreased ventilation by 1.3+-0.5 L min-1 and breathing frequency by 2.0+-0.9 breaths min-1 (both p&lt;=0.041).	Morphine	28-36	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
28976734-6	2017	Over 3.5 +- 0.4 h, 10 wt % Cu-BTTri/PVA membranes converted 97 +- 6% of GSNO into NO, with a maximum NO flux of 0.20 +- 0.02 nmol cm-2 min-1.	cu-bttri	27-35	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
28976734-6	2017	Over 3.5 +- 0.4 h, 10 wt % Cu-BTTri/PVA membranes converted 97 +- 6% of GSNO into NO, with a maximum NO flux of 0.20 +- 0.02 nmol cm-2 min-1.	Polyvinyl Alcohol	36-39	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
28636497-5	2017	RDDs in AL region for males and females, respectively, were 34.7 x 10-2 and 28.8 x 10-2 microg min-1 for PM10, 65.7 x 10-2 and 56.9 x 10-2 microg min-1 for PM2.5, and 76.5 x 10-2 and 66.3 x 10-2 microg min-1 for PM1.	Aluminum	8-10	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
28972366-5	2017	In aqueous solutions under simulated solar illumination the modified cathode is photochemically active for hydrogen production, generating the product gas with near-unity Faradaic efficiency at a rate of  10 muL min-1 cm-2 when studied in a three-electrode configuration and polarized at the equilibrium potential of the H+/H2 couple.	Hydrogen	107-115	CD59 molecule (CD59 blood group)	Homo sapiens	212-217
28972366-5	2017	In aqueous solutions under simulated solar illumination the modified cathode is photochemically active for hydrogen production, generating the product gas with near-unity Faradaic efficiency at a rate of  10 muL min-1 cm-2 when studied in a three-electrode configuration and polarized at the equilibrium potential of the H+/H2 couple.	Hydrogen	324-326	CD59 molecule (CD59 blood group)	Homo sapiens	212-217
29025775-3	2017	Creatinine levels at the time of gadolinium exposure were 0.9-1.2 mg/dL, with a corresponding estimated glomerular filtration rate of 64 mL/min/1.73m2 by modification of diet in renal disease equation.	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	140-145
28734966-5	2017	Using single fluorescent-molecule imaging, we have found that ganglioside probes dynamically enter and leave rafts featuring CD59, a GPI-anchored protein.	Gangliosides	62-73	CD59 molecule (CD59 blood group)	Homo sapiens	125-129
28734966-7	2017	The residency time of our ganglioside probes in rafts with CD59 oligomers was 48ms, after stimulation.	Gangliosides	26-37	CD59 molecule (CD59 blood group)	Homo sapiens	59-63
28636497-5	2017	RDDs in AL region for males and females, respectively, were 34.7 x 10-2 and 28.8 x 10-2 microg min-1 for PM10, 65.7 x 10-2 and 56.9 x 10-2 microg min-1 for PM2.5, and 76.5 x 10-2 and 66.3 x 10-2 microg min-1 for PM1.	Aluminum	8-10	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
28636497-5	2017	RDDs in AL region for males and females, respectively, were 34.7 x 10-2 and 28.8 x 10-2 microg min-1 for PM10, 65.7 x 10-2 and 56.9 x 10-2 microg min-1 for PM2.5, and 76.5 x 10-2 and 66.3 x 10-2 microg min-1 for PM1.	Aluminum	8-10	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
28937782-13	2017	CONCLUSIONS:   With cold-water immersion, the cooling rate in CCs (0.255 C min-1) was greater than in FBs (0.156 C min-1); however, both were considered ideal (&gt;=0.155 C min-1).	Water	25-30	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
28198604-7	2017	Pulling one tire (12.5 kg) required an oxygen uptake of 27 (4) mL kg-1 min-1 at 4 km h-1 and 0% inclination.	Oxygen	39-45	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
28198604-8	2017	Adding one more tire (6 kg) drove the oxygen uptake further up to 39 (4) mL kg-1 min-1.	Oxygen	38-44	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
28429121-7	2017	Mean preoperative creatinine clearance was 80 ml/min/1.73 m2.	Creatinine	18-28	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
28429121-13	2017	The mean creatinine clearance at last follow-up was 104.3 ml/min/1.73 m2.	Creatinine	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
28673877-5	2017	In comparison to baseline, remifentanil infusion &gt;0.05mug/Kg-1/min-1 produced a significant reduction of Ti/Ttotneu and Ti/Ttotmec, by prolonging the expiratory time.	Remifentanil	27-39	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
29114415-9	2017	Results: The mean dosage of remifentanil administered as a continuous infusion was 0.029+-0.0042 mug kg-1 min-1.	Remifentanil	28-40	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
28858494-5	2017	From this structure-activity relationship (SAR) study, novel irreversible inhibitors were identified that block the transamidation activity of hTG2 and allosterically abolish its GTP binding ability with a high degree of selectivity and efficiency (kinact/KI &gt; 105 M-1 min-1).	Guanosine Triphosphate	179-182	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
28881130-4	2017	The highest active Co catalyst with a total turnover frequency of 93.8 min-1 was successfully obtained, which exceeded the values of all the reported heterogeneous noble metal-free catalysts.	Metals	170-175	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
28846412-6	2017	Respective estimated Vmax values (maximum metabolic rate) for these metabolites were 11.8 +- 4, 0.6 +- 0.1, and 10.1 +- 0.8 pmol min-1 mg protein-1 in TBECH mixture and 4992 +- 1340, 14.1 +- 4.9, and 66.1 +- 7.3 pmol min-1 mg protein-1 in beta-TBECH.	tbech	151-156	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
28970805-6	2017	Results: Peak power output (POpeak) was 359 +- 48 W. Maximal oxygen consumption ([Formula: see text]O2max) was 3.87 +- 0.46 L min-1.	Oxygen	61-67	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
28807791-6	2017	eGFR in patients receiving bosutinib declined over time with more patients developing Grade &gt;= 3b eGFR (&lt; 45 mL/min/1.73 m2 according to the Modification of Diet in Renal Disease method) with second-line or later bosutinib (139/570, 24%) compared with first-line bosutinib (26/248, 10%) and imatinib (25/251, 10%); time to Grade &gt;= 3b eGFR was shortest with second-line or later bosutinib.	bosutinib	27-36	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
28926966-8	2017	ARC is currently defined as an increased creatinine clearance of greater than 130 mL/min/1.73 m2 best measured by 8-24 h urine collection.	Creatinine	41-51	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
28520394-6	2017	To lower the inhibition, an ATP recycling system and pyrophosphatase were used and resulted in a significant (~3-fold) enhancement in the rate of AD production (~5.7 mumol L-1 min-1).	Adenosine Triphosphate	28-31	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
28520394-6	2017	To lower the inhibition, an ATP recycling system and pyrophosphatase were used and resulted in a significant (~3-fold) enhancement in the rate of AD production (~5.7 mumol L-1 min-1).	amorpha-4,11-diene	146-148	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
28825831-6	2017	The crystalline fraction of (NH4)2SO4 was used to understand efflorescence behavior when the RH was linearly decreasing with a velocity of 1.2% RH min-1.	Ammonium Sulfate	28-37	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
29965258-3	2017	After biofilm formation and the biochemical system startup and operation by H2O2, the system was successfully started and steadily operated when H2O2was added into reactor A with the H2O2 voluve fraction of 3 mL L-1, doses of 100.0 mL, the flow velocity of 0.67 mL min-1, and dosing frequency of once a day.	h2o2was	145-152	CD59 molecule (CD59 blood group)	Homo sapiens	265-270
29965258-3	2017	After biofilm formation and the biochemical system startup and operation by H2O2, the system was successfully started and steadily operated when H2O2was added into reactor A with the H2O2 voluve fraction of 3 mL L-1, doses of 100.0 mL, the flow velocity of 0.67 mL min-1, and dosing frequency of once a day.	Hydrogen Peroxide	145-149	CD59 molecule (CD59 blood group)	Homo sapiens	265-270
28543041-10	2017	The CI-PPV group had lower mean (SD) pulse pressure variation values (9.5 (2.0)% vs. 11.9 (4.6)%; p = 0.003) and higher mean (SD) cardiac indices (2.76 (0.62) l min-1 .m-2 vs. 2.53 (0.66) l min-1 .m-2 ; p = 0.004) than the control group.	ci-ppv	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
28543041-10	2017	The CI-PPV group had lower mean (SD) pulse pressure variation values (9.5 (2.0)% vs. 11.9 (4.6)%; p = 0.003) and higher mean (SD) cardiac indices (2.76 (0.62) l min-1 .m-2 vs. 2.53 (0.66) l min-1 .m-2 ; p = 0.004) than the control group.	ci-ppv	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
28370390-10	2017	Dose-corrected area under the concentration-time curve for 100 mg over 4 h was 34% lower compared to 400 mg over 4 h. Midazolam eCLmet was 516 ml min-1 (420-640) following 100 mg 4 h-1 voriconazole, 152 ml min-1 (139-166) for 400 mg 6 h-1 , 192 ml min-1 (167-220) for 400 mg 4 h-1 , and 202 ml min-1 (189-217) for 400 mg 2 h-1 .	Midazolam	118-127	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
28370390-10	2017	Dose-corrected area under the concentration-time curve for 100 mg over 4 h was 34% lower compared to 400 mg over 4 h. Midazolam eCLmet was 516 ml min-1 (420-640) following 100 mg 4 h-1 voriconazole, 152 ml min-1 (139-166) for 400 mg 6 h-1 , 192 ml min-1 (167-220) for 400 mg 4 h-1 , and 202 ml min-1 (189-217) for 400 mg 2 h-1 .	Midazolam	118-127	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
28370390-10	2017	Dose-corrected area under the concentration-time curve for 100 mg over 4 h was 34% lower compared to 400 mg over 4 h. Midazolam eCLmet was 516 ml min-1 (420-640) following 100 mg 4 h-1 voriconazole, 152 ml min-1 (139-166) for 400 mg 6 h-1 , 192 ml min-1 (167-220) for 400 mg 4 h-1 , and 202 ml min-1 (189-217) for 400 mg 2 h-1 .	Midazolam	118-127	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
28370390-10	2017	Dose-corrected area under the concentration-time curve for 100 mg over 4 h was 34% lower compared to 400 mg over 4 h. Midazolam eCLmet was 516 ml min-1 (420-640) following 100 mg 4 h-1 voriconazole, 152 ml min-1 (139-166) for 400 mg 6 h-1 , 192 ml min-1 (167-220) for 400 mg 4 h-1 , and 202 ml min-1 (189-217) for 400 mg 2 h-1 .	Midazolam	118-127	CD59 molecule (CD59 blood group)	Homo sapiens	206-211
28500969-6	2017	For fresh water, marine culture water and sea water, the reaction rate constant was 0.066 min-1, 0.466 min-1 and 1.241 min-1, respectively.	Water	10-15	CD59 molecule (CD59 blood group)	Homo sapiens	103-114
28501570-3	2017	The apparent rate constant of levofloxacin decay was found to be 0.2883 min-1 for graphite felt-10 with the best performance at 200 mA, which is lower than graphite felt at 400 mA.	Levofloxacin	30-42	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
28501570-3	2017	The apparent rate constant of levofloxacin decay was found to be 0.2883 min-1 for graphite felt-10 with the best performance at 200 mA, which is lower than graphite felt at 400 mA.	Graphite	82-90	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
28699888-10	2017	The cutoff eGFR value predicting a subtherapeutic vancomycin level was 110.51 mL/min/1.73m&lt;sup&gt;2&lt;/sup&gt; (area under the curve, 0.753).	Vancomycin	50-60	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
28345790-4	2017	MATERIALS AND METHODS: We assessed central and peripheral metabolic responses to acyl ghrelin infusion (1 pmol kg-1  min-1 ) in healthy, lean subjects (n = 9) and non-diabetic, obese subjects (n = 9) before and 2 weeks after RYGB.	acyl ghrelin	81-93	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
28643390-7	2017	Significantly lower saliva secretion rates (ml min-1 ) were observed in patients with pSS for stimulated (0.62 +- 0.40 vs. 1.57 +- 0.71) and unstimulated (0.08 +- 0.07 vs. 0.29 +- 0.17) saliva.	pss	86-89	CD59 molecule (CD59 blood group)	Homo sapiens	47-52
28687885-6	2017	Under optimum chemical vapor generation conditions ([NaBH4] = 1.39%, [HCl] = 2.97 M, total liquid flow = 936 muL min-1), the proposed sample introduction system allowed the determination of arsenic, selenium, and mercury up to 5 mug g-1 with a limit of detection of 25, 140, and 13 mug kg-1, respectively.	Arsenic	190-197	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
28498908-3	2017	Chromatographic separation of lidocaine was achieved with a retention time of 7 min using a C18 column with a mobile phase comprising acetonitrile and potassium dihydrogen phosphate buffer (pH 5.5; 0.02 M) in the ratio of 26:74 at a flow rate of 1 mL min-1 with detection at 230 nm.	Lidocaine	30-39	CD59 molecule (CD59 blood group)	Homo sapiens	251-256
28506761-7	2017	For those in the highest tertile of cadmium exposure, the eGFR decreased by -12.68 mL/min/1.73 m2 (95% confidence interval -20.44, -4.93) and -11.22 mL/min/1.73 m2 (-17.01, -5.44), as urinary chromium or lead levels doubled, respectively.	Cadmium	36-43	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
28506761-7	2017	For those in the highest tertile of cadmium exposure, the eGFR decreased by -12.68 mL/min/1.73 m2 (95% confidence interval -20.44, -4.93) and -11.22 mL/min/1.73 m2 (-17.01, -5.44), as urinary chromium or lead levels doubled, respectively.	Cadmium	36-43	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
28928834-5	2017	In addition, following treatment with 0.1 U/ml phosphatidylinositol-specific phospholipase C (PI-PLC) for 1 h, CD55 and CD59 surface expression was significantly decreased, and the cell lysis rate was further enhanced.	Phosphatidylinositols	47-67	CD59 molecule (CD59 blood group)	Homo sapiens	120-124
28640009-11	2017	Median vancomycin clearance in those with versus without augmented renal clearance were 141.3 and 91.7 mL/min/1.73 m, respectively (p &lt; 0.001).	Vancomycin	7-17	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
28640009-15	2017	CONCLUSIONS: Augmented renal clearance was identified in one of 10 critically ill pediatric patients using vancomycin clearance, with an increase of approximately 50 mL/min/1.73 m in those with augmented renal clearance.	Vancomycin	107-117	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
28928892-0	2017	The Targeted Antitumor Effects of C- PC/CMC-CD59sp Nanoparticles on HeLa Cells in Vitro and in Vivo.	cmc	40-43	CD59 molecule (CD59 blood group)	Homo sapiens	44-48
28763209-3	2017	Upon scrutiny of the catalytic principles in the hydrolysis of ammonia-borane, the highest total turnover frequency among these first-row late transition metals is achieved for the templated Ni nanoparticles with 85.7 molH2 molcat-1 min-1 at room temperature, which overtakes performances of previous non-noble metal nanoparticles systems, and is even better than some noble metal nanoparticles systems.	Ammonia borane	63-77	CD59 molecule (CD59 blood group)	Homo sapiens	233-238
28763209-3	2017	Upon scrutiny of the catalytic principles in the hydrolysis of ammonia-borane, the highest total turnover frequency among these first-row late transition metals is achieved for the templated Ni nanoparticles with 85.7 molH2 molcat-1 min-1 at room temperature, which overtakes performances of previous non-noble metal nanoparticles systems, and is even better than some noble metal nanoparticles systems.	Metals	154-159	CD59 molecule (CD59 blood group)	Homo sapiens	233-238
28763209-3	2017	Upon scrutiny of the catalytic principles in the hydrolysis of ammonia-borane, the highest total turnover frequency among these first-row late transition metals is achieved for the templated Ni nanoparticles with 85.7 molH2 molcat-1 min-1 at room temperature, which overtakes performances of previous non-noble metal nanoparticles systems, and is even better than some noble metal nanoparticles systems.	Metals	311-316	CD59 molecule (CD59 blood group)	Homo sapiens	233-238
28731340-2	2017	In this work, we report the fabrication of an apparatus for sputter deposition of Li2S films ranging in thickness from a few nanometers to several micrometers at rates over 2 nm min-1.	li2s	82-86	CD59 molecule (CD59 blood group)	Homo sapiens	178-183
28527012-5	2017	Oxygen uptake ([Formula: see text]) was lower in the hypocapnia than control trials (822 +- 235 vs. 1645 +- 245 mL min-1; mean +- SD) during Ex1, but not Ex2 or Ex3, without a between-trial difference in the power output during the exercises.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
28556421-11	2017	There was a significant increase in the frequency of contractions after ciclosporin, tacrolimus, azathioprine and sirolimus treatment compared with control animals (4.6 +- 0.3 cycles min-1 ).	Cyclosporine	72-83	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
28556421-11	2017	There was a significant increase in the frequency of contractions after ciclosporin, tacrolimus, azathioprine and sirolimus treatment compared with control animals (4.6 +- 0.3 cycles min-1 ).	Azathioprine	97-109	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
28556421-11	2017	There was a significant increase in the frequency of contractions after ciclosporin, tacrolimus, azathioprine and sirolimus treatment compared with control animals (4.6 +- 0.3 cycles min-1 ).	Sirolimus	114-123	CD59 molecule (CD59 blood group)	Homo sapiens	183-188
27875282-7	2017	Mean carbohydrate utilization was 0.19 +- 0.1 g min-1 when patients were on mechanical ventilation compared with 0.15 +- 0.09 g min-1 upon liberation ( P &lt; .05).	Carbohydrates	5-17	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
28599629-7	2017	During surgery, M1, M2, and M3 patients received intravenous infusion of methoxamine at 2, 3, or 4 mug kg-1 min-1, respectively; the control group received saline of same volume at the same infusion rate.	Methoxamine	73-84	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
28374809-9	2017	Men had significantly higher resting oxygen uptake compared to women, 0.19 vs 0.15 l min-1 (P=0.005), REE per 24 h, 1286 vs 1030 kcal (P=0.003) and EE during weight-bearing activities.	Oxygen	37-43	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
28374809-10	2017	However, these became nonsignificant after adjustment for body weight and speed of movement, with a mean resting oxygen uptake of 2.47 ml O2 per kg min-1 for the whole group (women 2.43 and men 2.57 ml O2 kg-1 min-1, P=0.49).	Oxygen	113-119	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
28374809-13	2017	The mean resting oxygen uptake for the whole group was 2.47 ml O2 kg-1 min-1.	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
28660952-7	2017	In the case of the photochromic SiO2@VNF-1 NPs, the decoloration process followed a bi-exponential decay with fast rate constants (k1 = 1.6 x 10-1-1.6 min-1 and k2 = 9.1 x 10-3-1.3 x 10-1 min-1), which were responsible for the loss of coloration in less than 10 min.	Silicon Dioxide	32-36	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
28660952-7	2017	In the case of the photochromic SiO2@VNF-1 NPs, the decoloration process followed a bi-exponential decay with fast rate constants (k1 = 1.6 x 10-1-1.6 min-1 and k2 = 9.1 x 10-3-1.3 x 10-1 min-1), which were responsible for the loss of coloration in less than 10 min.	Silicon Dioxide	32-36	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
28665430-4	2017	Our strategy allowed the successful preparation of sub-centimeter-domain-sized graphene in 1 h with an average growth rate of 70 mum min-1, and with a hole mobility of 5500 cm2 V-1 S-1, which is sufficient for practical applications.	Graphite	79-87	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
28604370-8	2017	The experimental evaluation led to probed SCDD-Pro repeatability, dose rate dependence and linearity, that were better than 0.2%, 0.4% (in the 1.0-5.5 Gy min-1 range) and 0.4% (for dose higher than 0.05 Gy), respectively.	scdd-pro	42-50	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
28773097-5	2017	A maximum hydrogen generation rate of 35 mL min-1 was achieved when Cu sputtering power and time were 200 W and 60 min and while acid concentration and dealloying time were 18 M and 90 min, respectively.	Hydrogen	10-18	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
28773097-5	2017	A maximum hydrogen generation rate of 35 mL min-1 was achieved when Cu sputtering power and time were 200 W and 60 min and while acid concentration and dealloying time were 18 M and 90 min, respectively.	Copper	68-70	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
29657554-6	2017	Further, the circulation under 3 mL min-1 elevated the nitrate removal by 33% and the final nitrate concentration fell below the maximum contaminant level of 10 mg L-1 nitrate-nitrogen (NO3-N).	Nitrates	55-62	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
29657554-6	2017	Further, the circulation under 3 mL min-1 elevated the nitrate removal by 33% and the final nitrate concentration fell below the maximum contaminant level of 10 mg L-1 nitrate-nitrogen (NO3-N).	Nitrates	92-99	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
29657554-6	2017	Further, the circulation under 3 mL min-1 elevated the nitrate removal by 33% and the final nitrate concentration fell below the maximum contaminant level of 10 mg L-1 nitrate-nitrogen (NO3-N).	Nitrates	92-99	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
29657554-6	2017	Further, the circulation under 3 mL min-1 elevated the nitrate removal by 33% and the final nitrate concentration fell below the maximum contaminant level of 10 mg L-1 nitrate-nitrogen (NO3-N).	Nitrogen	176-184	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
29657554-6	2017	Further, the circulation under 3 mL min-1 elevated the nitrate removal by 33% and the final nitrate concentration fell below the maximum contaminant level of 10 mg L-1 nitrate-nitrogen (NO3-N).	no3-n	186-191	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
28476858-1	2017	Mutation of conserved cysteines in proteins of the Ly6 family cause human disease-chylomicronemia in the case of glycosylphosphatidylinositol-anchored HDL binding protein 1 (GPIHBP1) and paroxysmal nocturnal hemoglobinuria in the case of CD59.	Cysteine	22-31	CD59 molecule (CD59 blood group)	Homo sapiens	238-242
28476858-1	2017	Mutation of conserved cysteines in proteins of the Ly6 family cause human disease-chylomicronemia in the case of glycosylphosphatidylinositol-anchored HDL binding protein 1 (GPIHBP1) and paroxysmal nocturnal hemoglobinuria in the case of CD59.	ly6	51-54	CD59 molecule (CD59 blood group)	Homo sapiens	238-242
28775808-9	2017	Moreover, 34.7% of the fenofibrate group, but only 4.1% of the control group, exhibited an estimated glomerular filtration rate decrease &gt;=10 mL/min 1.73 m2 (P&lt;0.001).	Fenofibrate	23-34	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
28599629-16	2017	CONCLUSIONS: Intravenous infusion of methoxamine at 2-3 mug kg-1 min-1 can maintain stable hemodynamics in elderly patients during epidural anesthesia for hip-joint replacement surgery, without increasing the incidence of POCD.	Methoxamine	37-48	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
32264249-7	2017	However, the highest CBM migration rate, 1.76 mum2 min-1, was attained by regenerating alpha-cellulose in methanol, which also resulted in the maximum affinity of the biomolecule for the material.	Cellulose	87-102	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
32264249-7	2017	However, the highest CBM migration rate, 1.76 mum2 min-1, was attained by regenerating alpha-cellulose in methanol, which also resulted in the maximum affinity of the biomolecule for the material.	Methanol	106-114	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
28592575-18	2017	It may be necessary to monitor V and Cr levels in patients with an eGFR &lt;30 mL/min/1.73 m2.	Chromium	37-39	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
28177672-7	2017	Moreover, assays using human organ specimens revealed that the O-DMN-sulfating activities present in the cytosols of liver and small intestine (at 502.5 and 497.2 pmol min-1 (mg protein)-1, respectively) were much higher than those detected for the cytosols of lung and kidney.	desmethylnaproxen	63-68	CD59 molecule (CD59 blood group)	Homo sapiens	168-188
28467036-3	2017	The apparent alachlor degradation rate constant in the HTC-G/Fe(III)/H2O2 system (7.02 x 10-2 min-1) was about 3 times higher than that in the Fe(III)/H2O2 system (2.25 x 10-2 min-1).	alachlor	13-21	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
28583561-9	2017	In multivariate analysis, SUA was shown to be a significant predictor of developing stage 3 CKD (eGFR &lt;60 mL/min/1.72 m2), 1 year after donation in females but not in males.	sua	26-29	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
28583561-10	2017	CONCLUSIONS: Predonation SUA level is associated with the development of delayed renal recovery (GFR &lt;60 mL/min/1.72 m2) 1 year after donation in females but not in males.	sua	25-28	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
28480705-8	2017	Finally, Au@BDY-4T-BDY films showed good catalytic activity for the reduction of 4-nitrophenol to 4-aminophenol with rate constants of 1.3 x 10-2 and 9.2 x 10-3 min-1.	Gold	9-11	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
28480705-8	2017	Finally, Au@BDY-4T-BDY films showed good catalytic activity for the reduction of 4-nitrophenol to 4-aminophenol with rate constants of 1.3 x 10-2 and 9.2 x 10-3 min-1.	4-nitrophenol	81-94	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
28480705-8	2017	Finally, Au@BDY-4T-BDY films showed good catalytic activity for the reduction of 4-nitrophenol to 4-aminophenol with rate constants of 1.3 x 10-2 and 9.2 x 10-3 min-1.	4-aminophenol	98-111	CD59 molecule (CD59 blood group)	Homo sapiens	161-166
28443860-5	2017	About 85% of the capture efficiency has been achieved in cancer cell trapping experiments, in which a breast cancer cell line (MDA-MB-231) spiked with phosphate-buffered saline buffer when the pore size of the filter is 8 mum and the device is operated at a flow rate of 0.1 mL min-1.	Phosphate-Buffered Saline	151-176	CD59 molecule (CD59 blood group)	Homo sapiens	278-283
28467036-3	2017	The apparent alachlor degradation rate constant in the HTC-G/Fe(III)/H2O2 system (7.02 x 10-2 min-1) was about 3 times higher than that in the Fe(III)/H2O2 system (2.25 x 10-2 min-1).	alachlor	13-21	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
28467036-3	2017	The apparent alachlor degradation rate constant in the HTC-G/Fe(III)/H2O2 system (7.02 x 10-2 min-1) was about 3 times higher than that in the Fe(III)/H2O2 system (2.25 x 10-2 min-1).	ferric sulfate	61-68	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
28467036-3	2017	The apparent alachlor degradation rate constant in the HTC-G/Fe(III)/H2O2 system (7.02 x 10-2 min-1) was about 3 times higher than that in the Fe(III)/H2O2 system (2.25 x 10-2 min-1).	ferric sulfate	61-68	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
28467036-3	2017	The apparent alachlor degradation rate constant in the HTC-G/Fe(III)/H2O2 system (7.02 x 10-2 min-1) was about 3 times higher than that in the Fe(III)/H2O2 system (2.25 x 10-2 min-1).	Hydrogen Peroxide	69-73	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
28467036-3	2017	The apparent alachlor degradation rate constant in the HTC-G/Fe(III)/H2O2 system (7.02 x 10-2 min-1) was about 3 times higher than that in the Fe(III)/H2O2 system (2.25 x 10-2 min-1).	Hydrogen Peroxide	69-73	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
28247590-9	2017	The ethenolysis of commercial methyl oleate was also performed with a TOF of 8000 min-1 under microwave conditions.	methyl oleate	30-43	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
28868009-5	2017	We therefore proposed a treatment with full-dose crizotinib despite the renal impairment (creatinine clearance: 33 mL/min/1.73 m2) of unknown origin.	Crizotinib	49-59	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
28542228-2	2017	We investigated the expression of the local regulatory CS (reflected by CD46,CD55,CD59) in the peritoneal tissue of patients with different membrane function characteristics.	Cesium	55-57	CD59 molecule (CD59 blood group)	Homo sapiens	82-86
28516949-3	2017	The gene product of PIGA is required for the biosynthesis of glycosylphosphatidylinositol (GPI) anchors; thus, PIGA mutations lead to a deficiency of GPI-anchored proteins, such as complement decay-accelerating factor (also known as CD55) and CD59 glycoprotein (CD59), which are both complement inhibitors.	Glycosylphosphatidylinositols	61-89	CD59 molecule (CD59 blood group)	Homo sapiens	243-260
28516949-3	2017	The gene product of PIGA is required for the biosynthesis of glycosylphosphatidylinositol (GPI) anchors; thus, PIGA mutations lead to a deficiency of GPI-anchored proteins, such as complement decay-accelerating factor (also known as CD55) and CD59 glycoprotein (CD59), which are both complement inhibitors.	Glycosylphosphatidylinositols	61-89	CD59 molecule (CD59 blood group)	Homo sapiens	243-247
28516949-3	2017	The gene product of PIGA is required for the biosynthesis of glycosylphosphatidylinositol (GPI) anchors; thus, PIGA mutations lead to a deficiency of GPI-anchored proteins, such as complement decay-accelerating factor (also known as CD55) and CD59 glycoprotein (CD59), which are both complement inhibitors.	Glycosylphosphatidylinositols	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	243-260
28516949-3	2017	The gene product of PIGA is required for the biosynthesis of glycosylphosphatidylinositol (GPI) anchors; thus, PIGA mutations lead to a deficiency of GPI-anchored proteins, such as complement decay-accelerating factor (also known as CD55) and CD59 glycoprotein (CD59), which are both complement inhibitors.	Glycosylphosphatidylinositols	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	243-247
28467070-4	2017	In aqueous media (1% dimethyl sulfoxide in H2O), the two photodecarbonylation steps proceed much more slowly (k1 = 0.46-1.3 min-1 and k2 = 0.026-0.035 min-1, respectively) and the influence of the carboxyl groups is less pronounced.	Dimethyl Sulfoxide	21-39	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
28467070-4	2017	In aqueous media (1% dimethyl sulfoxide in H2O), the two photodecarbonylation steps proceed much more slowly (k1 = 0.46-1.3 min-1 and k2 = 0.026-0.035 min-1, respectively) and the influence of the carboxyl groups is less pronounced.	Dimethyl Sulfoxide	21-39	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
28467070-4	2017	In aqueous media (1% dimethyl sulfoxide in H2O), the two photodecarbonylation steps proceed much more slowly (k1 = 0.46-1.3 min-1 and k2 = 0.026-0.035 min-1, respectively) and the influence of the carboxyl groups is less pronounced.	Water	43-46	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
28467070-4	2017	In aqueous media (1% dimethyl sulfoxide in H2O), the two photodecarbonylation steps proceed much more slowly (k1 = 0.46-1.3 min-1 and k2 = 0.026-0.035 min-1, respectively) and the influence of the carboxyl groups is less pronounced.	Water	43-46	CD59 molecule (CD59 blood group)	Homo sapiens	151-156
28506221-5	2017	Reduced renal function was defined as eGFR of less than 60 mL/min/1.73 m2 measured using serum creatinine concentration (mg/dL).	Creatinine	95-105	CD59 molecule (CD59 blood group)	Homo sapiens	62-67
28259812-7	2017	Reducing the intensity of the solution recirculation from 60 to 10 mL min-1 significantly reduced specific energy consumption of the e-FO system from 0.693 +- 0.127 to 0.022 +- 0.004 kWh m-3 extracted water or from 1.103 +- 0.059 to 0.044 +- 0.002 kWh kg-1 reduced reversed solute.	Water	201-206	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
28277081-6	2017	The addition of 1 mL min-1 hydrogen peroxide has shown complete CBF degradation and 76% chemical oxygen demand removal under the following operating conditions of CBF ~50 mg L-1, TiO2 ~5 mg L-1 and feed flow rate ~82.5 mL min-1.	Hydrogen Peroxide	27-44	CD59 molecule (CD59 blood group)	Homo sapiens	21-26
28277081-6	2017	The addition of 1 mL min-1 hydrogen peroxide has shown complete CBF degradation and 76% chemical oxygen demand removal under the following operating conditions of CBF ~50 mg L-1, TiO2 ~5 mg L-1 and feed flow rate ~82.5 mL min-1.	Hydrogen Peroxide	27-44	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
28277081-6	2017	The addition of 1 mL min-1 hydrogen peroxide has shown complete CBF degradation and 76% chemical oxygen demand removal under the following operating conditions of CBF ~50 mg L-1, TiO2 ~5 mg L-1 and feed flow rate ~82.5 mL min-1.	Oxygen	97-103	CD59 molecule (CD59 blood group)	Homo sapiens	21-26
28277081-6	2017	The addition of 1 mL min-1 hydrogen peroxide has shown complete CBF degradation and 76% chemical oxygen demand removal under the following operating conditions of CBF ~50 mg L-1, TiO2 ~5 mg L-1 and feed flow rate ~82.5 mL min-1.	titanium dioxide	179-183	CD59 molecule (CD59 blood group)	Homo sapiens	21-26
28378455-3	2017	Here, phosphasalen indium catalysts feature high rates (30+-3 m-1  min-1 , THF, 298 K), high control, low loadings (0.2 mol %), and isoselectivity (Pi =0.92, THF, 258 K).	phosphasalen indium	6-25	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
28469190-4	2017	The degradation of atrazine follows a second-order kinetic model with constant values of K2 = 1.7957 g mg-1 min-1 for MK10_PEI_Cu NPs and K2 = 0.8133 g mg-1 min-1 for sand_PEI_Cu NPs.	Atrazine	19-27	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
28255987-4	2017	Phenylephrine was initially infused at 50 mug.min-1 , and metaraminol at 250 mug.min-1 .	Metaraminol	58-69	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
26303231-6	2017	Propranolol decreased cardiac output from 9 3 +- 2 8 l min-1 to 3 5 +- 0 47 l min-1 (P&lt;0 05).	Propranolol	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
26303231-6	2017	Propranolol decreased cardiac output from 9 3 +- 2 8 l min-1 to 3 5 +- 0 47 l min-1 (P&lt;0 05).	Propranolol	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
28181351-15	2017	The two general anesthesia groups showed lowest heart rates of 66.9 +- 15.9 min-1 for sevoflurane and 69.0 +- 11.5 min-1 for sevoflurane-propofol.	Sevoflurane	125-136	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
28181351-15	2017	The two general anesthesia groups showed lowest heart rates of 66.9 +- 15.9 min-1 for sevoflurane and 69.0 +- 11.5 min-1 for sevoflurane-propofol.	Propofol	137-145	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
28457398-10	2017	On the subgroup with GFR &lt;45 mL/min/1.73 m2, those on tacrolimus had lower MgS than those on cyclosporine, but those same patients presented with significantly different GFR, higher in the tacrolimus subgroup.	Tacrolimus	57-67	CD59 molecule (CD59 blood group)	Homo sapiens	35-40
28457398-13	2017	A significant difference on MgS levels between patients on tacrolimus and cyclosporine was found only when considering GFR &lt;45 mL/min/1.73 m2, in which patients on tacrolimus had significantly higher GFR than patients on cyclosporine, which may explain these results.	Magnesium	28-31	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
28457398-13	2017	A significant difference on MgS levels between patients on tacrolimus and cyclosporine was found only when considering GFR &lt;45 mL/min/1.73 m2, in which patients on tacrolimus had significantly higher GFR than patients on cyclosporine, which may explain these results.	Cyclosporine	74-86	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
28457398-13	2017	A significant difference on MgS levels between patients on tacrolimus and cyclosporine was found only when considering GFR &lt;45 mL/min/1.73 m2, in which patients on tacrolimus had significantly higher GFR than patients on cyclosporine, which may explain these results.	Tacrolimus	167-177	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
28425966-5	2017	Pre-training, resting lactate appearance was 3.6 +- 0.5 vs. 3.6 +- 0.4 mg kg-1 min-1 in GF and C, and was increased to 11.2 +- 1.4 vs. 8.8 +- 0.7 mg kg-1 min-1 by exercise (Exercise: p &lt; 0.01).	Lactic Acid	22-29	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
28425966-5	2017	Pre-training, resting lactate appearance was 3.6 +- 0.5 vs. 3.6 +- 0.4 mg kg-1 min-1 in GF and C, and was increased to 11.2 +- 1.4 vs. 8.8 +- 0.7 mg kg-1 min-1 by exercise (Exercise: p &lt; 0.01).	Lactic Acid	22-29	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Cholesterol	115-126	CD59 molecule (CD59 blood group)	Homo sapiens	307-311
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Cholesterol	115-126	CD59 molecule (CD59 blood group)	Homo sapiens	367-371
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Sphingosine	132-143	CD59 molecule (CD59 blood group)	Homo sapiens	307-311
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Sphingosine	132-143	CD59 molecule (CD59 blood group)	Homo sapiens	367-371
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Glycosylphosphatidylinositols	254-282	CD59 molecule (CD59 blood group)	Homo sapiens	307-311
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Glycosylphosphatidylinositols	254-282	CD59 molecule (CD59 blood group)	Homo sapiens	367-371
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Glycosylphosphatidylinositols	284-287	CD59 molecule (CD59 blood group)	Homo sapiens	307-311
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Glycosylphosphatidylinositols	284-287	CD59 molecule (CD59 blood group)	Homo sapiens	367-371
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Cholesterol	388-399	CD59 molecule (CD59 blood group)	Homo sapiens	307-311
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Cholesterol	388-399	CD59 molecule (CD59 blood group)	Homo sapiens	367-371
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Glycosylphosphatidylinositols	406-409	CD59 molecule (CD59 blood group)	Homo sapiens	307-311
28330937-5	2017	Single fluorescent molecule tracking in the live-cell PM revealed that they indirectly interact with each other in cholesterol- and sphingosine backbone-dependent manners, and that, for ~10-50 ms, they undergo transient colocalization-codiffusion with a glycosylphosphatidylinositol (GPI)-anchored protein, CD59 (in monomers, transient-dimer rafts, and clusters), in CD59-oligomer size-, cholesterol-, and GPI anchoring-dependent manners.	Glycosylphosphatidylinositols	406-409	CD59 molecule (CD59 blood group)	Homo sapiens	367-371
28137602-10	2017	Further characterisation of these newly identified hFMO3 substrates was performed determining their Km and kcat values that resulted to be 314 muM and 1.4 min-1 for selegiline and, 18 muM and 0.1 min-1 for clomiphene.	hfmo3	51-56	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
28137602-10	2017	Further characterisation of these newly identified hFMO3 substrates was performed determining their Km and kcat values that resulted to be 314 muM and 1.4 min-1 for selegiline and, 18 muM and 0.1 min-1 for clomiphene.	hfmo3	51-56	CD59 molecule (CD59 blood group)	Homo sapiens	196-201
28137602-10	2017	Further characterisation of these newly identified hFMO3 substrates was performed determining their Km and kcat values that resulted to be 314 muM and 1.4 min-1 for selegiline and, 18 muM and 0.1 min-1 for clomiphene.	Selegiline	165-175	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
28137602-10	2017	Further characterisation of these newly identified hFMO3 substrates was performed determining their Km and kcat values that resulted to be 314 muM and 1.4 min-1 for selegiline and, 18 muM and 0.1 min-1 for clomiphene.	Clomiphene	206-216	CD59 molecule (CD59 blood group)	Homo sapiens	196-201
28204886-4	2017	An acrolein permeation tube at 326.25 ng min-1 rate was used to generate gaseous standards.	Acrolein	3-11	CD59 molecule (CD59 blood group)	Homo sapiens	41-46
28403407-14	2017	The increase in P aCO 2 and end-tidal CO 2 during apnoea was 0.24 (0.05) and 0.12 (0.04) kPa min -1 , respectively.	Carbon Dioxide	19-23	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
28213568-6	2017	For example, eGFR 60-&lt;90 mL   min-1  (1.73 m2)-1 [vs &gt;=90 mL   min-1   (1.73 m2)-1] was associated with a [ratio (95% CI)] 1.21 (1.17-1.26), 1.14 (1.07-1.20), and 1.19 (1.12-1.27) times higher hs-cTnT, hs-cTnI, and NT-proBNP, respectively.	nt-probnp	221-230	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
28213568-6	2017	For example, eGFR 60-&lt;90 mL   min-1  (1.73 m2)-1 [vs &gt;=90 mL   min-1   (1.73 m2)-1] was associated with a [ratio (95% CI)] 1.21 (1.17-1.26), 1.14 (1.07-1.20), and 1.19 (1.12-1.27) times higher hs-cTnT, hs-cTnI, and NT-proBNP, respectively.	nt-probnp	221-230	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
27285539-11	2017	Preoperative DCE imaging indicated mean kTrans values of 0.49 +- 0.20 min-1 in Grade I meningiomas of the meningoepithelial subtype (n = 12), 0.27 +- 0.12 min-1 for Grade IV astrocytomas (n = 54), and 1.35 +- 0.74 min-1 for Grade I meningiomas of the MM subtype (n = 6).	ethylene dichloride	13-16	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
28286928-4	2017	The rate of ATP breakdown ranges from 70 to 140 mM min-1 during isometric contractions of various intensity to as much as 400 mM min-1 during intense, dynamic activity.	Adenosine Triphosphate	12-15	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
30382641-6	2017	After severing the right adrenal vein, noradrenaline (0.15 mug   kg-1   min-1), and dopamine (4mug   kg-1   min-1) were started and the patient was placed in the intensive care unit Inverted-takotsubo pattern asynergy is not very common, and treatment consists of supportive care, as in the usual takotsubo.	Dopamine	84-92	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
28181359-7	2017	A continuous infusion of propofol was started at 150 mug kg-1  min-1 .	Propofol	25-33	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
27995448-5	2017	hENT1 transports the substrate adenosine with a Km of 215 +- 34 micromol/L and a Vmax of 578 +- 23.4 nmol mg-1 min-1.	Adenosine	31-40	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
28271874-5	2017	Moreover, the ultrasound-assisted in situ method was also successfully applied to bimetallic systems, and MIL-101-supported amorphous CuCo, FeCo and NiCo NPs had the catalytic activities with total TOF values of 51.7, 50.8, and 44.3 molH2 molcat-1 min-1, respectively, which were the highest in the values of the reported non-noble metal Co-based catalysts.	MIL-101	106-113	CD59 molecule (CD59 blood group)	Homo sapiens	248-253
28271874-5	2017	Moreover, the ultrasound-assisted in situ method was also successfully applied to bimetallic systems, and MIL-101-supported amorphous CuCo, FeCo and NiCo NPs had the catalytic activities with total TOF values of 51.7, 50.8, and 44.3 molH2 molcat-1 min-1, respectively, which were the highest in the values of the reported non-noble metal Co-based catalysts.	Metals	84-89	CD59 molecule (CD59 blood group)	Homo sapiens	248-253
28222073-7	2017	Maximum tolerated dose for the combination was 240 mg per day oral rucaparib and carboplatin area under the curve 5 mg ml-1 min-1.	Carboplatin	81-92	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
28386234-9	2017	Results: With similar daily energy intake and physical activity, the increases in [Formula: see text]O2peak [NORM: 0.26 +- 0.37 L min-1 (+11.8%) vs. HYP: 0.54 +- 0.34 L min-1 (+26.1%)] and peak O2 pulse (NORM: +13.4% vs. HYP: +25.9%) for HYP were twice-larger than for NORM (p &lt; 0.05).	Oxygen	101-103	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
28386234-9	2017	Results: With similar daily energy intake and physical activity, the increases in [Formula: see text]O2peak [NORM: 0.26 +- 0.37 L min-1 (+11.8%) vs. HYP: 0.54 +- 0.34 L min-1 (+26.1%)] and peak O2 pulse (NORM: +13.4% vs. HYP: +25.9%) for HYP were twice-larger than for NORM (p &lt; 0.05).	Oxygen	101-103	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
28225181-5	2017	The scale-up of the present method was achieved at an isolated rate of 1.2 mg min-1 for the synthesis of 4-nitrobenzylaldehyde from 4-nitrobenzyl alcohol in the presence of sodium hypochlorite.	4-nitrobenzylaldehyde	105-126	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
28225181-5	2017	The scale-up of the present method was achieved at an isolated rate of 1.2 mg min-1 for the synthesis of 4-nitrobenzylaldehyde from 4-nitrobenzyl alcohol in the presence of sodium hypochlorite.	4-nitrobenzyl alcohol	132-153	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
28225181-5	2017	The scale-up of the present method was achieved at an isolated rate of 1.2 mg min-1 for the synthesis of 4-nitrobenzylaldehyde from 4-nitrobenzyl alcohol in the presence of sodium hypochlorite.	Sodium Hypochlorite	173-192	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
28435765-11	2017	The institution of a diet low in oxalates resulted in the rapid normalization of urinary oxalate excretion and urinary sediment and in the slow, continuous improvement of renal function to near normal levels (eGFR 59 mL/min/1.73 m2) before his death from a brain malignancy 3.5 years later.	Oxalates	33-41	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
28435765-11	2017	The institution of a diet low in oxalates resulted in the rapid normalization of urinary oxalate excretion and urinary sediment and in the slow, continuous improvement of renal function to near normal levels (eGFR 59 mL/min/1.73 m2) before his death from a brain malignancy 3.5 years later.	Oxalates	33-40	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
28326310-7	2017	Oxygen uptake after 3 min of squat exercises increased from 339+-40 mL min-1 to 1060+-160 mL min-1 with WBVT and 988+-124 mL min-1 without WBV (p=0.093).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
28326310-7	2017	Oxygen uptake after 3 min of squat exercises increased from 339+-40 mL min-1 to 1060+-160 mL min-1 with WBVT and 988+-124 mL min-1 without WBV (p=0.093).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
28326310-7	2017	Oxygen uptake after 3 min of squat exercises increased from 339+-40 mL min-1 to 1060+-160 mL min-1 with WBVT and 988+-124 mL min-1 without WBV (p=0.093).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
28286928-4	2017	The rate of ATP breakdown ranges from 70 to 140 mM min-1 during isometric contractions of various intensity to as much as 400 mM min-1 during intense, dynamic activity.	Adenosine Triphosphate	12-15	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
28286928-5	2017	The maximum rate of oxidative energy supply in untrained people is ~50 mM min-1 which, if the contraction duty cycle is 0.5 as is often the case in cyclic activity, is sufficient to match an ATP breakdown rate during contraction of 100 mM min-1.	Adenosine Triphosphate	191-194	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
28286928-7	2017	Glycolysis has the capacity to produce between 30 and 50 mM of ATP so that, for example, anaerobic glycolysis could provide ATP at an average of 100 mM min-1 over 30 s of exhausting activity.	Adenosine Triphosphate	63-66	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
28286928-7	2017	Glycolysis has the capacity to produce between 30 and 50 mM of ATP so that, for example, anaerobic glycolysis could provide ATP at an average of 100 mM min-1 over 30 s of exhausting activity.	Adenosine Triphosphate	124-127	CD59 molecule (CD59 blood group)	Homo sapiens	152-157
28207286-5	2017	A mobile phase of formic acid (0.1%) in water and methanol through a gradient of composition and a flow rate of 0.3 ml min-1 resulted in good separations of the analytes.	formic acid	18-29	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
28207286-5	2017	A mobile phase of formic acid (0.1%) in water and methanol through a gradient of composition and a flow rate of 0.3 ml min-1 resulted in good separations of the analytes.	Methanol	50-58	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
27628437-8	2017	CONCLUSIONS: Q24 h dosing of daptomycin up to 12 mg kg-1 provides comparable drug exposure in patients on CVVHD and in those with CrCl &gt;= 30 ml min-1 .	Daptomycin	29-39	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
27718269-7	2017	For AQ bioactivation, enzyme kinetical parameters were Km , 11.5 +- 2.0 mumol l-1 , Vmax , 59.2 +- 3.2 pmol min-1  mg-1 and CLint , 5.15 mul min-1  mg-1 .	Amodiaquine	4-6	CD59 molecule (CD59 blood group)	Homo sapiens	108-119
27718269-7	2017	For AQ bioactivation, enzyme kinetical parameters were Km , 11.5 +- 2.0 mumol l-1 , Vmax , 59.2 +- 3.2 pmol min-1  mg-1 and CLint , 5.15 mul min-1  mg-1 .	Amodiaquine	4-6	CD59 molecule (CD59 blood group)	Homo sapiens	141-152
28203745-11	2017	The mean rate of increase in ETCO2 was 0.03 kPa min-1.	etco2	29-34	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
28492790-6	2017	In addition to standard therapy, study group individuals received rhBNP by continuous infusion at 0.005 microg kg-1 min-1 for 72 hours.	rhbnp	66-71	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
28094471-3	2017	The desorption rate of water molecules increases from 10 to 18 mg min-1 , while the diameters of polyacrylonitrile fibers reduce from 1.02 to 0.14 microm.	Water	23-28	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
28347253-2	2017	Carboxymethyl chitosan loaded with the anticancer drug C-phycocyanin and the CD59-specific ligand peptide for cancer cell targeting were used to create C-phycocyanin/carboxymethyl chitosan-CD59-specific ligand peptide nanoparticles using the ionic-gelation method.	carboxymethyl-chitosan	0-22	CD59 molecule (CD59 blood group)	Homo sapiens	189-193
28347253-2	2017	Carboxymethyl chitosan loaded with the anticancer drug C-phycocyanin and the CD59-specific ligand peptide for cancer cell targeting were used to create C-phycocyanin/carboxymethyl chitosan-CD59-specific ligand peptide nanoparticles using the ionic-gelation method.	carboxymethyl-chitosan	166-188	CD59 molecule (CD59 blood group)	Homo sapiens	77-81
28347253-2	2017	Carboxymethyl chitosan loaded with the anticancer drug C-phycocyanin and the CD59-specific ligand peptide for cancer cell targeting were used to create C-phycocyanin/carboxymethyl chitosan-CD59-specific ligand peptide nanoparticles using the ionic-gelation method.	carboxymethyl-chitosan	166-188	CD59 molecule (CD59 blood group)	Homo sapiens	189-193
28347253-6	2017	Guided by the CD59-specific ligand peptide, the nanoparticles efficiently targeted the surface of HeLa cells and had an obvious inhibitory effect on HeLa cell proliferation as determined by methyl thiazolyl tetrazolium assays.	methyl thiazolyl tetrazolium	190-218	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
28120569-7	2017	In multiple logistic regression analysis, CKD-EPI-Cys eGFR was independently associated with osteopenia at the total hip (per 1 mL/min/1.73 m2 increase, odds ratio 0.98, 95% confidence interval 0.97-0.99, p=0.004) after adjusting for confounding variables.	ckd-epi-cys	42-53	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
29296960-6	2017	Carfilzomib was commonly associated with a transient reduction of estimated glomerular filtration rate (eGFR) but also improved renal function in 55% of patients with baseline eGFR &lt;60 mL/min/1.73 m2.	carfilzomib	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
28230742-1	2017	Peak exogenous carbohydrate oxidation rates typically reach ~1 g min-1 during exercise when ample glucose or glucose polymers are ingested.	Carbohydrates	15-27	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
28230742-1	2017	Peak exogenous carbohydrate oxidation rates typically reach ~1 g min-1 during exercise when ample glucose or glucose polymers are ingested.	Glucose	98-105	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
28230742-1	2017	Peak exogenous carbohydrate oxidation rates typically reach ~1 g min-1 during exercise when ample glucose or glucose polymers are ingested.	Glucose	109-116	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
28230742-1	2017	Peak exogenous carbohydrate oxidation rates typically reach ~1 g min-1 during exercise when ample glucose or glucose polymers are ingested.	Polymers	117-125	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
28230742-4	2017	Ten trained male cyclists (VO2peak: 65 +- 2 mL kg-1 min-1) cycled on four different occasions for 180 min at 50% Wmax during which they consumed a carbohydrate solution providing 1.8 g min-1 of glucose (GLU), 1.2 g min-1 glucose + 0.6 g min-1 fructose (GLU + FRU), 0.6 g min-1 glucose + 1.2 g min-1 sucrose (GLU + SUC), or water (WAT).	Carbohydrates	147-159	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
28230742-4	2017	Ten trained male cyclists (VO2peak: 65 +- 2 mL kg-1 min-1) cycled on four different occasions for 180 min at 50% Wmax during which they consumed a carbohydrate solution providing 1.8 g min-1 of glucose (GLU), 1.2 g min-1 glucose + 0.6 g min-1 fructose (GLU + FRU), 0.6 g min-1 glucose + 1.2 g min-1 sucrose (GLU + SUC), or water (WAT).	Carbohydrates	147-159	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
28230742-4	2017	Ten trained male cyclists (VO2peak: 65 +- 2 mL kg-1 min-1) cycled on four different occasions for 180 min at 50% Wmax during which they consumed a carbohydrate solution providing 1.8 g min-1 of glucose (GLU), 1.2 g min-1 glucose + 0.6 g min-1 fructose (GLU + FRU), 0.6 g min-1 glucose + 1.2 g min-1 sucrose (GLU + SUC), or water (WAT).	Carbohydrates	147-159	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
28230742-4	2017	Ten trained male cyclists (VO2peak: 65 +- 2 mL kg-1 min-1) cycled on four different occasions for 180 min at 50% Wmax during which they consumed a carbohydrate solution providing 1.8 g min-1 of glucose (GLU), 1.2 g min-1 glucose + 0.6 g min-1 fructose (GLU + FRU), 0.6 g min-1 glucose + 1.2 g min-1 sucrose (GLU + SUC), or water (WAT).	Carbohydrates	147-159	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
28230742-4	2017	Ten trained male cyclists (VO2peak: 65 +- 2 mL kg-1 min-1) cycled on four different occasions for 180 min at 50% Wmax during which they consumed a carbohydrate solution providing 1.8 g min-1 of glucose (GLU), 1.2 g min-1 glucose + 0.6 g min-1 fructose (GLU + FRU), 0.6 g min-1 glucose + 1.2 g min-1 sucrose (GLU + SUC), or water (WAT).	Carbohydrates	147-159	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
28230742-6	2017	In line, exogenous carbohydrate oxidation rates during the latter 120 min of exercise were 46% +- 8% higher in GLU + FRU or GLU + SUC compared with GLU (1.19 +- 0.12, 1.13 +- 0.21, and 0.82 +- 0.16 g min-1, respectively, p &lt; 0.05).	Carbohydrates	19-31	CD59 molecule (CD59 blood group)	Homo sapiens	200-205
28230742-7	2017	We conclude that fructose co-ingestion (0.6 g min-1) with glucose (1.2 g min-1) provided either as a monosaccharide or as sucrose strongly increases exogenous carbohydrate oxidation rates during prolonged exercise in trained cyclists.	Fructose	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
28230742-7	2017	We conclude that fructose co-ingestion (0.6 g min-1) with glucose (1.2 g min-1) provided either as a monosaccharide or as sucrose strongly increases exogenous carbohydrate oxidation rates during prolonged exercise in trained cyclists.	Fructose	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
28230742-7	2017	We conclude that fructose co-ingestion (0.6 g min-1) with glucose (1.2 g min-1) provided either as a monosaccharide or as sucrose strongly increases exogenous carbohydrate oxidation rates during prolonged exercise in trained cyclists.	Glucose	58-65	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
28230742-7	2017	We conclude that fructose co-ingestion (0.6 g min-1) with glucose (1.2 g min-1) provided either as a monosaccharide or as sucrose strongly increases exogenous carbohydrate oxidation rates during prolonged exercise in trained cyclists.	Monosaccharides	101-115	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
28230742-7	2017	We conclude that fructose co-ingestion (0.6 g min-1) with glucose (1.2 g min-1) provided either as a monosaccharide or as sucrose strongly increases exogenous carbohydrate oxidation rates during prolonged exercise in trained cyclists.	Sucrose	122-129	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
28230742-7	2017	We conclude that fructose co-ingestion (0.6 g min-1) with glucose (1.2 g min-1) provided either as a monosaccharide or as sucrose strongly increases exogenous carbohydrate oxidation rates during prolonged exercise in trained cyclists.	Carbohydrates	159-171	CD59 molecule (CD59 blood group)	Homo sapiens	46-51
28230742-7	2017	We conclude that fructose co-ingestion (0.6 g min-1) with glucose (1.2 g min-1) provided either as a monosaccharide or as sucrose strongly increases exogenous carbohydrate oxidation rates during prolonged exercise in trained cyclists.	Carbohydrates	159-171	CD59 molecule (CD59 blood group)	Homo sapiens	73-78
28239356-5	2017	The maximal oxygen uptake [Formula: see text] was higher in men than in women [4,492 +- 585 ml min-1 and 57.7 +- 4.4 ml kg-1 min-1 vs. 2,752.4 +- 187.9 ml min-1 (p &lt;= 0.001) and 50.0 +- 5.7 ml kg-1 min-1(p = 0.007), respectively].	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	95-100
28239356-5	2017	The maximal oxygen uptake [Formula: see text] was higher in men than in women [4,492 +- 585 ml min-1 and 57.7 +- 4.4 ml kg-1 min-1 vs. 2,752.4 +- 187.9 ml min-1 (p &lt;= 0.001) and 50.0 +- 5.7 ml kg-1 min-1(p = 0.007), respectively].	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
28239356-5	2017	The maximal oxygen uptake [Formula: see text] was higher in men than in women [4,492 +- 585 ml min-1 and 57.7 +- 4.4 ml kg-1 min-1 vs. 2,752.4 +- 187.9 ml min-1 (p &lt;= 0.001) and 50.0 +- 5.7 ml kg-1 min-1(p = 0.007), respectively].	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
28239356-5	2017	The maximal oxygen uptake [Formula: see text] was higher in men than in women [4,492 +- 585 ml min-1 and 57.7 +- 4.4 ml kg-1 min-1 vs. 2,752.4 +- 187.9 ml min-1 (p &lt;= 0.001) and 50.0 +- 5.7 ml kg-1 min-1(p = 0.007), respectively].	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
28178996-6	2017	Reduced cardiac output in the moderate and mild in silico ARDS patients produced significant drops in oxygen delivery during the RM (average decrease of 423 ml min-1 and 526 ml min-1, respectively).	Oxygen	102-108	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
28178996-6	2017	Reduced cardiac output in the moderate and mild in silico ARDS patients produced significant drops in oxygen delivery during the RM (average decrease of 423 ml min-1 and 526 ml min-1, respectively).	Oxygen	102-108	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
28178996-7	2017	In the in-silico patients with severe ARDS, however, significantly improved gas-exchange led to an average increase of 89 ml min-1 in oxygen delivery during the RM, despite a simultaneous fall in cardiac output of more than 3 l min-1 on average.	Oxygen	134-140	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
28178996-9	2017	In patients with high baseline cardiac outputs (&gt;6.5 l min-1), oxygen delivery never fell below 700 ml min-1.	Oxygen	66-72	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
28155845-6	2017	We simulated the flow velocity, shear stress and diffusion of glucose molecules inside and outside the culture chambers under a continuous flow rate of 1 mul min-1.	Glucose	62-69	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
28177744-8	2017	Whole-body oxygen consumption was also significantly higher in hot and cold compared with room temperature (0.38 +- 0.01 L min-1, p &lt; 0.001; 0.52 +- 0.03 L min-1, p &lt; 0.001; 0.35 +- 0.01 L min-1, respectively).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
28177744-8	2017	Whole-body oxygen consumption was also significantly higher in hot and cold compared with room temperature (0.38 +- 0.01 L min-1, p &lt; 0.001; 0.52 +- 0.03 L min-1, p &lt; 0.001; 0.35 +- 0.01 L min-1, respectively).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
28177744-8	2017	Whole-body oxygen consumption was also significantly higher in hot and cold compared with room temperature (0.38 +- 0.01 L min-1, p &lt; 0.001; 0.52 +- 0.03 L min-1, p &lt; 0.001; 0.35 +- 0.01 L min-1, respectively).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
27621150-6	2017	PF-05190457 dose-dependently blocked ghrelin (1 pmol kg-1  min-1 )-induced growth hormone (GH) release with (mean [90% confidence interval]) 77% [63-85%] inhibition at 100 mg. PF-05190457 (150 mg) delayed gastric emptying lag time by 30% [7-58%] and half emptying time by 20% [7-35%] with a corresponding decrease in postprandial glucose by 9 mg dL-1 .	Ghrelin	37-44	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
27332955-5	2017	A subgroup of 15 subjects continued with 3-min cycling exercise in hypoxia with subsequent evaluation followed by an assessment 1 min at rest while breathing 4 L min-1 oxygen.	Oxygen	168-174	CD59 molecule (CD59 blood group)	Homo sapiens	162-167
28039190-7	2017	Endurance training attenuated the IH-induced increase in chemoreflex sensitivity (pretraining: Delta 0.045 +- 0.026 vs. posttraining: Delta -0.028 +- 0.040 l min-1 % O2 desaturation-1; P = 0.045).	Ile-His	34-36	CD59 molecule (CD59 blood group)	Homo sapiens	158-163
27709794-6	2017	Glucose (AUCglucose 319 +- 30 [placebo] vs 315 +- 18 mmol.L-1 .min-1 [sitagliptin], Delta 7 [95% confidence interval -50 to 63] mmol.L-1 .min-1 ), insulin, C-peptide and glucagon concentrations were not affected significantly by sitagliptin treatment ( P = .60-1.00).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
28100527-10	2017	Transcutaneous CO2 increased to a similar extent in both arms, with 2.4 (95% CI 0.5) mm Hg min-1 for the control arm and 2.4 (95% CI 0.4) mm Hg min-1 for the THRIVE arm.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	15-18	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
28611786-8	2017	Treatment with spironolactone was associated with increased potassium (delta potassium 0.31 +- 0.55 vs. 0.05 +- 0.41 mmol/L, p &lt; 0.001) and decreased eGFR (delta eGFR -4.12 +- 12.2 vs. -0.98 +- 7.88 mL/min/1.73 m2, p = 0.006) compared to the non-spironolactone group.	Spironolactone	15-29	CD59 molecule (CD59 blood group)	Homo sapiens	205-210
27709794-6	2017	Glucose (AUCglucose 319 +- 30 [placebo] vs 315 +- 18 mmol.L-1 .min-1 [sitagliptin], Delta 7 [95% confidence interval -50 to 63] mmol.L-1 .min-1 ), insulin, C-peptide and glucagon concentrations were not affected significantly by sitagliptin treatment ( P = .60-1.00).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	138-143
27709794-6	2017	Glucose (AUCglucose 319 +- 30 [placebo] vs 315 +- 18 mmol.L-1 .min-1 [sitagliptin], Delta 7 [95% confidence interval -50 to 63] mmol.L-1 .min-1 ), insulin, C-peptide and glucagon concentrations were not affected significantly by sitagliptin treatment ( P = .60-1.00).	Sitagliptin Phosphate	70-81	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
28043929-4	2017	RESULTS: The glucose disposal rate (M value) increased significantly at 3 months after RYGB (from 3.36 +- 1.26 mg kg-1 min-1 to 6.30 +- 1.3 mg kg-1 min-1, p &lt; 0.001).	Glucose	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
28043929-4	2017	RESULTS: The glucose disposal rate (M value) increased significantly at 3 months after RYGB (from 3.36 +- 1.26 mg kg-1 min-1 to 6.30 +- 1.3 mg kg-1 min-1, p &lt; 0.001).	Glucose	13-20	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
27914351-10	2017	Based on Langmuir-Hinshelwood kinetic model, apparent rate constants of Fe2O3-TiO2 and P25 were 9.2 x 10-3 and 2.7 x 10-3 min-1, respectively.	fe2o3-tio2	72-82	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
27927703-4	2017	Mecamylamine"s estimated clearance was 0.28 +- 0.015 L min-1.	Mecamylamine	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	55-60
27851893-7	2017	Main effects showed mean VO2 significantly higher (~1.5-2ml kg-1 min-1) for CAF for RPE4 and RPE7.	Caffeine	76-79	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
28067397-2	2017	This complex promoted chemical and photochemical water oxidation efficiently with turnover frequencies of 0.28 s-1 and 5 min-1, respectively.	Water	49-54	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
28001158-3	2017	Here, we focus on the mechanism of a water-head-driven oscillator and analyze the functions of its flow-switching period (T) and flow rate (Q) in a wide range (0.1 s-5.9 h and 2 muL min-1-2 mL min-1).	Water	37-42	CD59 molecule (CD59 blood group)	Homo sapiens	182-189
28001158-3	2017	Here, we focus on the mechanism of a water-head-driven oscillator and analyze the functions of its flow-switching period (T) and flow rate (Q) in a wide range (0.1 s-5.9 h and 2 muL min-1-2 mL min-1).	Water	37-42	CD59 molecule (CD59 blood group)	Homo sapiens	182-187
28081262-7	2017	Hazard ratios (HRs) [95% confidence intervals (CIs)] for statin treatment for the doubling of serum creatinine levels were significant only in CKD patients with an estimated glomerular filtration rate (eGFR) &gt;=30 mL/min/1.73 m2, and were 0.744 (0.635-0.873) in the unmatched cohort and 0.767 (0.596-0.986) in the matched cohort.	Creatinine	100-110	CD59 molecule (CD59 blood group)	Homo sapiens	219-224
28972944-5	2017	Peak creatinine levels were &gt;4 times above the baseline and estimated glomerular filtration rates were reduced to &lt;30 mL/min/1.73 m2.	Creatinine	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
28215043-4	2017	Oxygen at 6 L min-1 was administered by a facial mask.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	14-19
28362031-11	2017	The automatic group consumed more anaesthetic and oxygen per minute (sevoflurane 0.1171 mL min-1; IQR: 0.0503; oxygen 1.8286 mL min-1, IQR: 1,3751) than MANUAL-ET (sevoflurane 0.0824 mL min-1, IQR: 0.0305; oxygen 1,288 mL min-1, IQR: 0,6517) (P = 0.0028 and P = 0.0171, respectively).	Oxygen	50-56	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
28362031-11	2017	The automatic group consumed more anaesthetic and oxygen per minute (sevoflurane 0.1171 mL min-1; IQR: 0.0503; oxygen 1.8286 mL min-1, IQR: 1,3751) than MANUAL-ET (sevoflurane 0.0824 mL min-1, IQR: 0.0305; oxygen 1,288 mL min-1, IQR: 0,6517) (P = 0.0028 and P = 0.0171, respectively).	Sevoflurane	69-80	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
29129868-3	2017	After optimization of the reaction cell gas, it was found that the best performance for measuring BaF+ could be achieved at a flow rate of O2 in the range from 0.65 to 0.75 mL min-1.	Oxygen	139-141	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
27749042-3	2016	Amorphous Al2O3 thin films were found to have an etch rate of 0.5 nm min-1 and an increase in roughness of ~0.01 nm min-1.	Aluminum Oxide	10-15	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
27840416-7	2017	RESULTS: In both the groups (P&lt;0.001), the incremental areas under the curve (iAUC)0-60 min for glucose was greater with the 3 kcal min-1 than the 1 kcal min-1 infusion; the iAUC0-120 min for glucose during 3 kcal min-1 was greater (P&lt;0.05), in the obese.	Glucose	99-106	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
27840416-7	2017	RESULTS: In both the groups (P&lt;0.001), the incremental areas under the curve (iAUC)0-60 min for glucose was greater with the 3 kcal min-1 than the 1 kcal min-1 infusion; the iAUC0-120 min for glucose during 3 kcal min-1 was greater (P&lt;0.05), in the obese.	Glucose	99-106	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
27840416-7	2017	RESULTS: In both the groups (P&lt;0.001), the incremental areas under the curve (iAUC)0-60 min for glucose was greater with the 3 kcal min-1 than the 1 kcal min-1 infusion; the iAUC0-120 min for glucose during 3 kcal min-1 was greater (P&lt;0.05), in the obese.	Glucose	99-106	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
27840416-7	2017	RESULTS: In both the groups (P&lt;0.001), the incremental areas under the curve (iAUC)0-60 min for glucose was greater with the 3 kcal min-1 than the 1 kcal min-1 infusion; the iAUC0-120 min for glucose during 3 kcal min-1 was greater (P&lt;0.05), in the obese.	Glucose	195-202	CD59 molecule (CD59 blood group)	Homo sapiens	135-140
28074703-8	2017	Results Postoperative creatinine clearance was lower in patients who underwent surgery &lt;=3 days after coronary angiography (63.57 +- 38.52 mL min-1) compared to &gt;=8 days after coronary angiography (74.56 +- 54.25 mL min-1, p = 0.015).	Creatinine	22-32	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
28074703-8	2017	Results Postoperative creatinine clearance was lower in patients who underwent surgery &lt;=3 days after coronary angiography (63.57 +- 38.52 mL min-1) compared to &gt;=8 days after coronary angiography (74.56 +- 54.25 mL min-1, p = 0.015).	Creatinine	22-32	CD59 molecule (CD59 blood group)	Homo sapiens	222-227
28074703-9	2017	Patients who underwent surgery &lt;=3 days after coronary angiography had higher hospital mortality when preoperative creatinine clearance was &lt;=60 mL min-1 (12% vs. 4% for creatinine clearance &lt;=and &gt;60 mL min-1, respectively; p = 0.039).	Creatinine	118-128	CD59 molecule (CD59 blood group)	Homo sapiens	154-159
29187913-9	2017	Laboratory testing shows minimum interferences or carryover between consecutive samples, low blanks, and a reproducible, linear response between the DTT consumption rate (nmol min-1) and PQ concentration (muM).	Dithiothreitol	149-152	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
29187913-9	2017	Laboratory testing shows minimum interferences or carryover between consecutive samples, low blanks, and a reproducible, linear response between the DTT consumption rate (nmol min-1) and PQ concentration (muM).	9,10-phenanthrenequinone	187-189	CD59 molecule (CD59 blood group)	Homo sapiens	176-181
29187913-12	2017	The DTT consumption rates (nmol min-1) obtained with the o-MOCA were within experimental uncertainties of those previously reported for these DEP samples.	Dithiothreitol	4-7	CD59 molecule (CD59 blood group)	Homo sapiens	32-37
29130036-6	2017	Bland-Altman analysis showed a bias between CIBIO and CIPAC of 0.52 liters min-1 m-2, with LOA of [-2.2; 1.1] liters min-1 m-2.	cibio	44-49	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
29130036-6	2017	Bland-Altman analysis showed a bias between CIBIO and CIPAC of 0.52 liters min-1 m-2, with LOA of [-2.2; 1.1] liters min-1 m-2.	cipac	54-59	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
28680334-7	2017	CD59 levels of beta-TM patients were not significantly different than beta-TI patients and controls, but CD35 levels were significantly lower in the beta-TM patients (3.56 +-4.87%) and beta-TI patients (12.48 +-9.19%) than in the control group (39.98 +-15.01%) (p &lt; 0.01).	Thulium	19-22	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
27941058-3	2017	Glucose (3 kcal min-1) was infused via an intraduodenal manometry catheter for 60 min.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	16-21
27213514-7	2017	The water consumption rate was approximately 2.35 L min-1, while the total power consumed was 270 W. This study demonstrates that the ESWS could be a potentially effective and feasible tool in controlling PM emissions for commercial poultry facilities.	Water	4-9	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
27802417-7	2017	In 8 healthy volunteers, we then infused increasing doses of sodium nitrite (1, 10, and 30 nmol kg-1 min-1) intravenously.	Sodium Nitrite	61-75	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
29238624-4	2017	The optimized analytical conditions of LCGD-AES were pH = 1 with HNO3 as electrolyte, 650 V discharge voltage, and 3 mL min-1 solution flow rate.	lcgd	39-43	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
27098170-5	2017	Using a response surface methodology (RSM) experiment, it was shown that DPPH radical inhibition of SAP1&lt;MW&lt;3kDa increased to 90.22 +- 0.90% at the optimal conditions (electric field intensity 15 kV cm-1 , pulse frequency 1600 Hz and flow velocity 2.93 mL min-1 ).	1,1-diphenyl-2-picrylhydrazyl	73-77	CD59 molecule (CD59 blood group)	Homo sapiens	262-267
28291958-8	2017	Nevertheless, the eGFR values differed among the four baPWV groups; the baPWV values were significantly higher in the subjects at the CKD (eGFR&lt;60 mL/min/1.73 m2) and the early CKD stage (eGFR60-80 mL/min/1.73 m2).	bapwv	72-77	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
28291958-8	2017	Nevertheless, the eGFR values differed among the four baPWV groups; the baPWV values were significantly higher in the subjects at the CKD (eGFR&lt;60 mL/min/1.73 m2) and the early CKD stage (eGFR60-80 mL/min/1.73 m2).	bapwv	72-77	CD59 molecule (CD59 blood group)	Homo sapiens	204-209
28082428-3	2017	In each trial, participants ingested 1.2 g min-1 of glucose (enriched with 13C glucose) and 0.6 g min-1 of fructose (enriched with 13C fructose) directly before and every 15 min during exercise.	Fructose	107-115	CD59 molecule (CD59 blood group)	Homo sapiens	43-103
28082428-6	2017	Peak exogenous carbohydrate oxidation was lower at altitude (1.13 +- 0.2 g min-1) than sea level (1.42 +- 0.16 g min-1, P = 0.034, ES = 1.33).	Carbohydrates	15-27	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
28082428-6	2017	Peak exogenous carbohydrate oxidation was lower at altitude (1.13 +- 0.2 g min-1) than sea level (1.42 +- 0.16 g min-1, P = 0.034, ES = 1.33).	Carbohydrates	15-27	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
27585276-8	2016	The equilibrium adsorption amount and rate for Fe-SC-800 is high to 148.99mgg-1 and 0.015gmg-1min-1, respectively.	fe-sc-800	47-56	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
28031758-5	2016	Significantly lower maximal oxygen uptake (VO2max, ml kg-1 min-1) was observed for GIV (56.6 +- 3.8) compared to GI (59.6 +- 3.9), GII (59.4 +- 4.2) and GIV (59.7 +- 4.1).	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
27837997-5	2016	However, the optimum, or near optimum, flow rate was 5mL-min-1, producing a system pressure of 580bar (with 40% methanol, outlet pressure 120bar).	Methanol	112-120	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
27910935-3	2016	Intermedilysin is a cholesterol-dependent cytolysin that requires the human immune receptor CD59, in addition to cholesterol, to form giant beta-barrel pores in host membranes.	Cholesterol	20-31	CD59 molecule (CD59 blood group)	Homo sapiens	92-96
27914501-4	2016	Patients will be randomly assigned to receive either intravenous levosimendan (0.2 mug kg-1 min-1 for the first hour followed by 0.1 mug/kg for 23hours) or matching placebo initiated within 8hours of surgery.	Simendan	65-77	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
26462495-4	2016	At the beginning of anaesthesia induction, continuous infusion of remifentanil (1 mug min-1 kg-1) preceded hypnosis with propofol in 13 patients [non-hypnosis group; mean age, 67.8 (17.5) years], while propofol bolus (30-50 mg) was injected together with continuous remifentanil medication in 18 patients [hypnosis group; mean age, 62.9 (16.5) years].	Remifentanil	66-78	CD59 molecule (CD59 blood group)	Homo sapiens	86-96
30379462-3	2016	The patient received inhalation induction with 5% sevoflurane and an infusion of remifentanil (0.2mug   kg-1   min-1).	Remifentanil	81-93	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
27663694-7	2016	In the postanesthesia care unit, O2 flow was started at 5 l min-1 , reduced to 2 and then 0.25 l min-1 every 3 min.	Oxygen	33-35	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
27663694-7	2016	In the postanesthesia care unit, O2 flow was started at 5 l min-1 , reduced to 2 and then 0.25 l min-1 every 3 min.	Oxygen	33-35	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
27663694-12	2016	Peak CO2 values measurement was less affected by a change in flow rate in mainstream mask group than in side stream NC group (P = 0.04 in 5-0.25 l min-1 O2 flow change).	Carbon Dioxide	5-8	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
27747790-5	2016	RESULTS: Maximal oxygen uptake (VO2max) was 56.17 +- 4.95 and 46.04 +- 3.25 ml kg-1 min-1 in ATL and NATL, respectively.	Oxygen	17-23	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
27809324-6	2016	This microfluidic fuel cell is able to generate a voltage up to ~450 mV from 10 mM of glucose with a flow rate of 20 muL min-1.	Glucose	86-93	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
27783521-2	2016	By alternately bubbling CO2 and N2 at a moderate conditions (30  C, 80 mL min-1), silica nanoparticles reversibly switch between amphipathic and hydrophilic as a result of the adsorption of ammonium (CO2) and the desorption of tertiary amine (N2).	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	24-27	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
27783521-2	2016	By alternately bubbling CO2 and N2 at a moderate conditions (30  C, 80 mL min-1), silica nanoparticles reversibly switch between amphipathic and hydrophilic as a result of the adsorption of ammonium (CO2) and the desorption of tertiary amine (N2).	Nitrogen	32-34	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
27783521-2	2016	By alternately bubbling CO2 and N2 at a moderate conditions (30  C, 80 mL min-1), silica nanoparticles reversibly switch between amphipathic and hydrophilic as a result of the adsorption of ammonium (CO2) and the desorption of tertiary amine (N2).	Silicon Dioxide	82-88	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
27783521-2	2016	By alternately bubbling CO2 and N2 at a moderate conditions (30  C, 80 mL min-1), silica nanoparticles reversibly switch between amphipathic and hydrophilic as a result of the adsorption of ammonium (CO2) and the desorption of tertiary amine (N2).	Ammonium Compounds	190-198	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
27895592-9	2016	The main result was that the MSIT group substantially improved parameters related to physical capacity (+5.31 +- 5.12 ml min-1/kg in maximal oxygen uptake at T6) in comparison with the MSCTL group (-0.97 +- 4.89 ml min-1/kg at T6; group effect: p = 0.0004).	Oxygen	141-147	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
27830718-6	2016	The average total terpene emission rate from the use of herbs and pepper during cooking is estimated to be 46 +- 5 gg-1Herbs min-1.	Terpenes	18-25	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
27779854-5	2016	Even under nonaqueous conditions, both oxygen and illumination together show slow oxidation of iron over the course of a few hours, consistent with forming an Fe3+-O2- intermediate as corroborated by resonance-enhanced Raman spectroscopy, with a rate constant of k = 3.03(8) x 10-3 min-1.	Iron	95-99	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
27779854-5	2016	Even under nonaqueous conditions, both oxygen and illumination together show slow oxidation of iron over the course of a few hours, consistent with forming an Fe3+-O2- intermediate as corroborated by resonance-enhanced Raman spectroscopy, with a rate constant of k = 3.03(8) x 10-3 min-1.	fe3+-o2	159-166	CD59 molecule (CD59 blood group)	Homo sapiens	282-287
27734470-4	2016	However, it appears that intra-operative remifentanil infusion rates of above 0.25 mug.kg-1 .min-1 are associated with higher postoperative opioid consumption, suggesting tolerance.	Remifentanil	41-53	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
27240662-9	2016	The Vmax values for the free and immobilized enzymes were calculated as 1.75 and 1.03 mumol mg-1 min-1, in order, when starch was used as the substrate.	Starch	119-125	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
27557975-8	2016	The photocatalyst, synthesized at optimum conditions was able to remove 99.1 % acetaminophen with rate constant of 7.9 x 10-3 min-1, which was 4.88 times greater than virgin TiO2.	Acetaminophen	79-92	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
27557975-8	2016	The photocatalyst, synthesized at optimum conditions was able to remove 99.1 % acetaminophen with rate constant of 7.9 x 10-3 min-1, which was 4.88 times greater than virgin TiO2.	titanium dioxide	174-178	CD59 molecule (CD59 blood group)	Homo sapiens	126-131
27858805-3	2016	With the initial dye concentration being controlled at 300 mg L-1, the optimized conditions for wastewater treatment are 3.68, 29.19 and 18.49 mg min-1 for initial pH, mole ratio of [H2O2]/[Fe2+] and ozone dosage, respectively.	Hydrogen Peroxide	183-187	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
27858805-3	2016	With the initial dye concentration being controlled at 300 mg L-1, the optimized conditions for wastewater treatment are 3.68, 29.19 and 18.49 mg min-1 for initial pH, mole ratio of [H2O2]/[Fe2+] and ozone dosage, respectively.	ammonium ferrous sulfate	190-194	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
27658705-5	2016	When operated under continuous flow at a rate of 1 mL min-1 and at room temperature, up to 99.95 % of the Pd2+ ions could be removed from a stock solution with an initial concentration of 100 ppm.	PALLADIUM ION	106-110	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
27404673-9	2016	Likewise, in patients whose eGFR was 30mL/min/1.73m(2) or above, tolvaptan reduced the risk of combined events (HR: 0.54, 95% CI: 0.32-0.90, P=0.017) with a significant interaction (P value for interaction=0.015).	Tolvaptan	65-74	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
27739456-4	2016	By using surface complexation kinetic models (SCKMs) to describe phosphate adsorption to PF-HFO, the adsorption rate constant (0.0386-0.205 mM-1 min-1 for SCKM-1 and 0.0680-0.274 mM-1 min-1 for SCKM-2) decreased with increasing pH while the protonation reaction rate constant in SCKM-2 (0.0776-0.0947 mM-1 min-1) increased over the pH range 6.0-8.0.	Phosphates	65-74	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
27739456-4	2016	By using surface complexation kinetic models (SCKMs) to describe phosphate adsorption to PF-HFO, the adsorption rate constant (0.0386-0.205 mM-1 min-1 for SCKM-1 and 0.0680-0.274 mM-1 min-1 for SCKM-2) decreased with increasing pH while the protonation reaction rate constant in SCKM-2 (0.0776-0.0947 mM-1 min-1) increased over the pH range 6.0-8.0.	Phosphates	65-74	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
27739456-4	2016	By using surface complexation kinetic models (SCKMs) to describe phosphate adsorption to PF-HFO, the adsorption rate constant (0.0386-0.205 mM-1 min-1 for SCKM-1 and 0.0680-0.274 mM-1 min-1 for SCKM-2) decreased with increasing pH while the protonation reaction rate constant in SCKM-2 (0.0776-0.0947 mM-1 min-1) increased over the pH range 6.0-8.0.	Phosphates	65-74	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
27739456-4	2016	By using surface complexation kinetic models (SCKMs) to describe phosphate adsorption to PF-HFO, the adsorption rate constant (0.0386-0.205 mM-1 min-1 for SCKM-1 and 0.0680-0.274 mM-1 min-1 for SCKM-2) decreased with increasing pH while the protonation reaction rate constant in SCKM-2 (0.0776-0.0947 mM-1 min-1) increased over the pH range 6.0-8.0.	pyrazofurin	89-91	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
27739456-4	2016	By using surface complexation kinetic models (SCKMs) to describe phosphate adsorption to PF-HFO, the adsorption rate constant (0.0386-0.205 mM-1 min-1 for SCKM-1 and 0.0680-0.274 mM-1 min-1 for SCKM-2) decreased with increasing pH while the protonation reaction rate constant in SCKM-2 (0.0776-0.0947 mM-1 min-1) increased over the pH range 6.0-8.0.	pyrazofurin	89-91	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
27739456-4	2016	By using surface complexation kinetic models (SCKMs) to describe phosphate adsorption to PF-HFO, the adsorption rate constant (0.0386-0.205 mM-1 min-1 for SCKM-1 and 0.0680-0.274 mM-1 min-1 for SCKM-2) decreased with increasing pH while the protonation reaction rate constant in SCKM-2 (0.0776-0.0947 mM-1 min-1) increased over the pH range 6.0-8.0.	pyrazofurin	89-91	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
27739456-4	2016	By using surface complexation kinetic models (SCKMs) to describe phosphate adsorption to PF-HFO, the adsorption rate constant (0.0386-0.205 mM-1 min-1 for SCKM-1 and 0.0680-0.274 mM-1 min-1 for SCKM-2) decreased with increasing pH while the protonation reaction rate constant in SCKM-2 (0.0776-0.0947 mM-1 min-1) increased over the pH range 6.0-8.0.	ferric oxide	92-95	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
27749042-3	2016	Amorphous Al2O3 thin films were found to have an etch rate of 0.5 nm min-1 and an increase in roughness of ~0.01 nm min-1.	Aluminum Oxide	10-15	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
27562642-2	2016	The maximum growth rate can reach 300 mum min-1 , several orders of magnitude higher than previously reported values for millimeter-sized single-crystalline graphene growth on Cu foils.	Graphite	157-165	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
27562642-2	2016	The maximum growth rate can reach 300 mum min-1 , several orders of magnitude higher than previously reported values for millimeter-sized single-crystalline graphene growth on Cu foils.	Copper	176-178	CD59 molecule (CD59 blood group)	Homo sapiens	42-47
27530230-6	2016	Insulin decreased (P &lt; 0.01) whole body phenylalanine rate of appearance (mumol kg-1 min-1), indicating suppression of muscle proteolysis, in both the control (1.02 +- 0.04 vs 0.76 +- 0.04) and the BCAA (0.89 +- 0.07 vs 0.61 +- 0.03) experiments, but the change was not different between the two experiments (P &gt; 0.05).	Phenylalanine	43-56	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
27704869-8	2016	Individual responses to CAF were labeled positive using a criterion of 13.4 m min-1 faster for CAF (vs. PLA).	Caffeine	24-27	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
27704869-8	2016	Individual responses to CAF were labeled positive using a criterion of 13.4 m min-1 faster for CAF (vs. PLA).	Caffeine	95-98	CD59 molecule (CD59 blood group)	Homo sapiens	78-83
27704869-10	2016	In these, systematic increases were observed for heart rate (~12 beats min-1) and oxygen consumption (~5.7 mL kg-1 min-1).	Oxygen	82-88	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
27273555-6	2016	The estimated scopolamine population mean apparent central and peripheral volume of distribution was 2.66 +- 1.050 l and 62.10 +- 10.100 l, respectively and the clearance was 1.09 +- 0.096 l min(-1) .	Scopolamine	14-25	CD59 molecule (CD59 blood group)	Homo sapiens	191-197
28077536-8	2016	The cerebral tissue oxygen saturation measured with FORE-SIGHT  started at 68 (sd 13)% and increased by 0.0142% min-1 (P&lt;0.01).	Oxygen	20-26	CD59 molecule (CD59 blood group)	Homo sapiens	112-117
27183025-12	2016	In addition to an altered pharmacokinetics (p &lt; 0.01), a reduced pharmacodynamics response to furosemide also became important when creatinine clearance was reduced to less than 40 mL/min/1.73 m (p = 0.01).	Furosemide	97-107	CD59 molecule (CD59 blood group)	Homo sapiens	187-192
26936082-5	2016	The optimal condition for achieving the maximum H2S adsorption capacity for biochar is obtained as the follows: carbonization temperature (500 C), duration (5.7 min), SV (7300 L min(-1) kg(-1)) with H2S removal reaching 60 mg g(-1).	Hydrogen Sulfide	48-51	CD59 molecule (CD59 blood group)	Homo sapiens	178-184
27336358-10	2016	Before surgery, beta-cell glucose sensitivity was higher in PPHG than No-PPHG in both RYGB (118 +- 67 vs 65 +- 24 pmol/min-1   m2   mM-1) and LSG patients (114 +- 32 vs 86 +- 33) (both P = .02) and improved in all subjects after surgery.	Glucose	26-33	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
27324913-5	2016	Among them, seven patients had a baseline creatinine clearance (CrCl) &lt;50 ml min(-1) (case).	Creatinine	42-52	CD59 molecule (CD59 blood group)	Homo sapiens	80-86
27324913-5	2016	Among them, seven patients had a baseline creatinine clearance (CrCl) &lt;50 ml min(-1) (case).	crcl	64-68	CD59 molecule (CD59 blood group)	Homo sapiens	80-86
27324913-9	2016	Although CrCl &lt;50 ml min(-1) was associated with higher voriconazole concentrations, its clinical impact remains unclear.	Voriconazole	59-71	CD59 molecule (CD59 blood group)	Homo sapiens	24-30
27038225-8	2016	Moreover, p-synephrine increased maximal fat oxidation rate (0.29 +- 0.15 vs. 0.40 +- 0.18 g min(-1) ; P = 0.01) during exercise although it did not affect the intensity at which maximal fat oxidation was achieved (55.8 +- 7.7 vs. 56.7 +- 8.2% VO2peak ; P = 0.51).	Synephrine	10-22	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
27589373-8	2016	The asymmetric charge coated microporous activated graphene exhibits exceptional electrosorption capacity of 18.43 mg g(-1) at a flow rate of 20 mL min(-1) upon applied cell potential of 1.4 V with initial NaCl concentration of 300 mg L(-1), high charge efficiency, excellent recyclability, and, moreover, good antibacterial behavior.	Graphite	51-59	CD59 molecule (CD59 blood group)	Homo sapiens	148-154
27499440-5	2016	The CDC consensus undecapeptide motif, which for the CD59-responsive CDCs has a proline instead of a tryptophan in the motif, adopts a strikingly different conformation between the structures; our data suggest that the proline acts as a selectivity switch to ensure CD59-dependent CDCs bind their protein receptor first in preference to cholesterol.	Proline	80-87	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
27499440-5	2016	The CDC consensus undecapeptide motif, which for the CD59-responsive CDCs has a proline instead of a tryptophan in the motif, adopts a strikingly different conformation between the structures; our data suggest that the proline acts as a selectivity switch to ensure CD59-dependent CDCs bind their protein receptor first in preference to cholesterol.	Proline	80-87	CD59 molecule (CD59 blood group)	Homo sapiens	266-270
27499440-5	2016	The CDC consensus undecapeptide motif, which for the CD59-responsive CDCs has a proline instead of a tryptophan in the motif, adopts a strikingly different conformation between the structures; our data suggest that the proline acts as a selectivity switch to ensure CD59-dependent CDCs bind their protein receptor first in preference to cholesterol.	Tryptophan	101-111	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
27499440-5	2016	The CDC consensus undecapeptide motif, which for the CD59-responsive CDCs has a proline instead of a tryptophan in the motif, adopts a strikingly different conformation between the structures; our data suggest that the proline acts as a selectivity switch to ensure CD59-dependent CDCs bind their protein receptor first in preference to cholesterol.	Tryptophan	101-111	CD59 molecule (CD59 blood group)	Homo sapiens	266-270
27499440-5	2016	The CDC consensus undecapeptide motif, which for the CD59-responsive CDCs has a proline instead of a tryptophan in the motif, adopts a strikingly different conformation between the structures; our data suggest that the proline acts as a selectivity switch to ensure CD59-dependent CDCs bind their protein receptor first in preference to cholesterol.	Proline	219-226	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
27499440-5	2016	The CDC consensus undecapeptide motif, which for the CD59-responsive CDCs has a proline instead of a tryptophan in the motif, adopts a strikingly different conformation between the structures; our data suggest that the proline acts as a selectivity switch to ensure CD59-dependent CDCs bind their protein receptor first in preference to cholesterol.	Proline	219-226	CD59 molecule (CD59 blood group)	Homo sapiens	266-270
27499440-5	2016	The CDC consensus undecapeptide motif, which for the CD59-responsive CDCs has a proline instead of a tryptophan in the motif, adopts a strikingly different conformation between the structures; our data suggest that the proline acts as a selectivity switch to ensure CD59-dependent CDCs bind their protein receptor first in preference to cholesterol.	Cholesterol	337-348	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
27499440-5	2016	The CDC consensus undecapeptide motif, which for the CD59-responsive CDCs has a proline instead of a tryptophan in the motif, adopts a strikingly different conformation between the structures; our data suggest that the proline acts as a selectivity switch to ensure CD59-dependent CDCs bind their protein receptor first in preference to cholesterol.	Cholesterol	337-348	CD59 molecule (CD59 blood group)	Homo sapiens	266-270
27115790-7	2016	Severe renal impairment (creatinine clearance &lt;30 ml min(-1) ; n = 3) decreased ADC exposures (0.71 [0.54, 0.94]) and increased MMAE exposures (1.90 [0.85, 4.21]).	Creatinine	25-35	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
27270293-7	2016	RESULTS: In pooled, multivariable-adjusted analyses, log-transformed, creatinine-normalized urinary KIM-1 levels were higher in those with lower eGFR {beta = -0.03 per 10 mL/min/1.73 m(2) [95% confidence interval (CI) -0.05 to -0.02]} and greater albuminuria [beta = 0.16 per unit of log albumin:creatinine ratio (95% CI 0.15-0.17)].	Creatinine	70-80	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
27307294-9	2016	All-trans retinoic acid increased CD38 levels and decreased CD55 and CD59 expression on MM cells from patients who developed daratumumab resistance, to approximately pretreatment values.	Tretinoin	10-23	CD59 molecule (CD59 blood group)	Homo sapiens	69-73
27532605-8	2016	Caffeine reduced ratings of perceived exertion (mean difference: 0.5 +- 0.7; 95% likely range: 0.1 to 0.9) and heart rate (mean difference: 3.6 +- 4.2 b min-1; 95% likely range: 1.3 to 5.8 b min-1) during exercise, with the effect on the latter dissipating as exercise intensity increased.	Caffeine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
27532605-8	2016	Caffeine reduced ratings of perceived exertion (mean difference: 0.5 +- 0.7; 95% likely range: 0.1 to 0.9) and heart rate (mean difference: 3.6 +- 4.2 b min-1; 95% likely range: 1.3 to 5.8 b min-1) during exercise, with the effect on the latter dissipating as exercise intensity increased.	Caffeine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	191-196
26778747-5	2016	Moreover, A+C therapy yielded a 4.21 mL/min/1.73 m(2) lower estimated glomerular filtration rate reduction than other combinations (P&lt;.001).	Actinium	10-13	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
27368711-3	2016	As proof-of-concept in the rat, we generated an anemia model, SD-Tg(CD59-HBA1)Bryd, which expresses hCD59 on erythrocytes.	sd-tg	62-67	CD59 molecule (CD59 blood group)	Homo sapiens	100-105
27306111-0	2016	Reduction of Argon Consumption to Less than 2 L min(-1) by Gas Recycling in Inductively Coupled Plasma Optical Emission Spectrometry.	Argon	13-18	CD59 molecule (CD59 blood group)	Homo sapiens	48-54
27306111-3	2016	Thereby, the total argon consumption could be reduced from 14 to 1.4 L min(-1) using a standard torch and without restricting the rf power.	Argon	19-24	CD59 molecule (CD59 blood group)	Homo sapiens	71-77
27244216-3	2016	Herein, we describe the design of a novel symmetrical membrane reactor with a sandwich-like structure, whereby a largescale production (&gt;10 mL min(-1)  cm(-2) ) of hydrogen and syngas can be obtained simultaneously on opposite sides of the OTM.	Hydrogen	167-175	CD59 molecule (CD59 blood group)	Homo sapiens	146-152
27413017-13	2016	CONCLUSIONS:  Sulphonylurea treatment in patients with a renal function of less than 30 mL/min/1.73 m(2) should be considered with caution.	Sulfonylurea Compounds	14-27	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
28149379-4	2016	Multi-exponential modeling showed values above 450 ml min-1 of the SC in the two last bouts of exercise (those with intensities above the lactate threshold).	Lactic Acid	138-145	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
27330129-6	2016	However, there have been millions of people exposed to metformin for many years, many of them with serum creatinine values at or close to 1.5 mg/dL with estimated glomerular filtration rates (eGFRs) much below 60 mL/min/1.73 m(2) who have not developed lactic acidosis.	Metformin	55-64	CD59 molecule (CD59 blood group)	Homo sapiens	216-221
26786299-11	2016	The length of exposure to tranexamic acid treatment was significantly more prolonged in women whose estimated glomerular filtration rate remained &lt;15mL/min/1.73m(2) (7.1+-4.8 vs 2.9+-2.4 hours; P=0.03).	Tranexamic Acid	26-41	CD59 molecule (CD59 blood group)	Homo sapiens	155-160
26879802-12	2016	The clearances of urea and creatinine were 6.89 (range 4.50-7.55) and 7.46 (range 4.79-10.50) mL/min/1.73 m(2), respectively, with conventional PD and 19 (17.0-30.0) and 41 (standard deviation17.4, range 12.0-52.0) mL/min/1.73 m(2), respectively, with CFPD (both p = 0.043).	Urea	18-22	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
27243608-6	2016	By using the N-doped multilayer composites, high hydrogen generation specific rate of 5560 mL min(-1) gCo(-1) was achieved at room temperature.	Hydrogen	49-57	CD59 molecule (CD59 blood group)	Homo sapiens	94-100
27087551-9	2016	A reproducible mass emission rate of 0.97 +- 0.10 ng min(-1) (n = 8) was observed for PFBA.	pfba	86-90	CD59 molecule (CD59 blood group)	Homo sapiens	53-59
27087551-11	2016	Conversely, generating gas phase perfluorononanoic acid (PFNA) by sublimating the solid acid under the same conditions produced a mass emission rate of 2800 ng min(-1), which is equivalent to a mixing ratio of 18 ppthv and over a million times higher than suspected atmospheric levels.	perfluorononanoic acid	33-55	CD59 molecule (CD59 blood group)	Homo sapiens	160-166
27087551-11	2016	Conversely, generating gas phase perfluorononanoic acid (PFNA) by sublimating the solid acid under the same conditions produced a mass emission rate of 2800 ng min(-1), which is equivalent to a mixing ratio of 18 ppthv and over a million times higher than suspected atmospheric levels.	perfluorononanoic acid	57-61	CD59 molecule (CD59 blood group)	Homo sapiens	160-166
27159266-2	2016	Argon, at a flow rate of 60 mL min(-1), was the best DBD discharge gas.	Argon	0-5	CD59 molecule (CD59 blood group)	Homo sapiens	31-37
27159266-9	2016	Addition of 7 mL min(-1) O2 to the Ar plasma discharge resulted in a quantitative retention of arsane in the optical arm of the DBD atomizer.	Oxygen	25-27	CD59 molecule (CD59 blood group)	Homo sapiens	17-23
27159266-9	2016	Addition of 7 mL min(-1) O2 to the Ar plasma discharge resulted in a quantitative retention of arsane in the optical arm of the DBD atomizer.	Argon	35-37	CD59 molecule (CD59 blood group)	Homo sapiens	17-23
27159266-9	2016	Addition of 7 mL min(-1) O2 to the Ar plasma discharge resulted in a quantitative retention of arsane in the optical arm of the DBD atomizer.	arsane	95-101	CD59 molecule (CD59 blood group)	Homo sapiens	17-23
27159266-9	2016	Addition of 7 mL min(-1) O2 to the Ar plasma discharge resulted in a quantitative retention of arsane in the optical arm of the DBD atomizer.	dbd	128-131	CD59 molecule (CD59 blood group)	Homo sapiens	17-23
27061704-1	2016	A second passivation and a multistage carbon-source supply (CSS) allow a 50-fold enhancement of the growth rate of large single-crystalline graphene with a record growth rate of 101 mum min(-1) , almost 10 times higher than for pure copper.	thiocysteine	60-63	CD59 molecule (CD59 blood group)	Homo sapiens	186-192
27061704-1	2016	A second passivation and a multistage carbon-source supply (CSS) allow a 50-fold enhancement of the growth rate of large single-crystalline graphene with a record growth rate of 101 mum min(-1) , almost 10 times higher than for pure copper.	Graphite	140-148	CD59 molecule (CD59 blood group)	Homo sapiens	186-192
27208681-6	2016	A combination of any two of: P(a)o(2) &lt;= 10.5 kPa, FEV(1) &lt;= 60% predicted, and PEF &lt;= 350 L   min(-1) predicted the need for in-flight oxygen with a sensitivity of 89% and a specificity of 69%.	Oxygen	145-151	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
27427607-7	2016	It was found that both GRs and fiber contributed to the hydrogen generation rate of Co/GRs-PANFs (3222 mL x min(-1) x g(-1)), which is much higher than that of cobalt powders (915 mL x min(-1) x g(-1)) and Co/GRs (995 mL x min(-1) x g(-1)).	Hydrogen	56-64	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
27043189-4	2016	Single-fluorescent-molecule imaging in the live-cell plasma membrane revealed the clear but transient colocalization and codiffusion of fluorescent ganglioside analogs with a fluorescently labeled glycosylphosphatidylinisotol (GPI)-anchored protein, human CD59, with lifetimes of 12 ms for CD59 monomers, 40 ms for CD59"s transient homodimer rafts in quiescent cells, and 48 ms for engaged-CD59-cluster rafts, in cholesterol- and GPI-anchoring-dependent manners.	Gangliosides	148-159	CD59 molecule (CD59 blood group)	Homo sapiens	256-260
27043189-4	2016	Single-fluorescent-molecule imaging in the live-cell plasma membrane revealed the clear but transient colocalization and codiffusion of fluorescent ganglioside analogs with a fluorescently labeled glycosylphosphatidylinisotol (GPI)-anchored protein, human CD59, with lifetimes of 12 ms for CD59 monomers, 40 ms for CD59"s transient homodimer rafts in quiescent cells, and 48 ms for engaged-CD59-cluster rafts, in cholesterol- and GPI-anchoring-dependent manners.	Gangliosides	148-159	CD59 molecule (CD59 blood group)	Homo sapiens	290-294
27043189-4	2016	Single-fluorescent-molecule imaging in the live-cell plasma membrane revealed the clear but transient colocalization and codiffusion of fluorescent ganglioside analogs with a fluorescently labeled glycosylphosphatidylinisotol (GPI)-anchored protein, human CD59, with lifetimes of 12 ms for CD59 monomers, 40 ms for CD59"s transient homodimer rafts in quiescent cells, and 48 ms for engaged-CD59-cluster rafts, in cholesterol- and GPI-anchoring-dependent manners.	Gangliosides	148-159	CD59 molecule (CD59 blood group)	Homo sapiens	290-294
27043189-4	2016	Single-fluorescent-molecule imaging in the live-cell plasma membrane revealed the clear but transient colocalization and codiffusion of fluorescent ganglioside analogs with a fluorescently labeled glycosylphosphatidylinisotol (GPI)-anchored protein, human CD59, with lifetimes of 12 ms for CD59 monomers, 40 ms for CD59"s transient homodimer rafts in quiescent cells, and 48 ms for engaged-CD59-cluster rafts, in cholesterol- and GPI-anchoring-dependent manners.	glycosylphosphatidylinisotol	197-225	CD59 molecule (CD59 blood group)	Homo sapiens	256-260
27043189-4	2016	Single-fluorescent-molecule imaging in the live-cell plasma membrane revealed the clear but transient colocalization and codiffusion of fluorescent ganglioside analogs with a fluorescently labeled glycosylphosphatidylinisotol (GPI)-anchored protein, human CD59, with lifetimes of 12 ms for CD59 monomers, 40 ms for CD59"s transient homodimer rafts in quiescent cells, and 48 ms for engaged-CD59-cluster rafts, in cholesterol- and GPI-anchoring-dependent manners.	glycosylphosphatidylinisotol	197-225	CD59 molecule (CD59 blood group)	Homo sapiens	290-294
27043189-4	2016	Single-fluorescent-molecule imaging in the live-cell plasma membrane revealed the clear but transient colocalization and codiffusion of fluorescent ganglioside analogs with a fluorescently labeled glycosylphosphatidylinisotol (GPI)-anchored protein, human CD59, with lifetimes of 12 ms for CD59 monomers, 40 ms for CD59"s transient homodimer rafts in quiescent cells, and 48 ms for engaged-CD59-cluster rafts, in cholesterol- and GPI-anchoring-dependent manners.	glycosylphosphatidylinisotol	197-225	CD59 molecule (CD59 blood group)	Homo sapiens	290-294
27043189-4	2016	Single-fluorescent-molecule imaging in the live-cell plasma membrane revealed the clear but transient colocalization and codiffusion of fluorescent ganglioside analogs with a fluorescently labeled glycosylphosphatidylinisotol (GPI)-anchored protein, human CD59, with lifetimes of 12 ms for CD59 monomers, 40 ms for CD59"s transient homodimer rafts in quiescent cells, and 48 ms for engaged-CD59-cluster rafts, in cholesterol- and GPI-anchoring-dependent manners.	GPI 1046	227-230	CD59 molecule (CD59 blood group)	Homo sapiens	256-260
27043189-4	2016	Single-fluorescent-molecule imaging in the live-cell plasma membrane revealed the clear but transient colocalization and codiffusion of fluorescent ganglioside analogs with a fluorescently labeled glycosylphosphatidylinisotol (GPI)-anchored protein, human CD59, with lifetimes of 12 ms for CD59 monomers, 40 ms for CD59"s transient homodimer rafts in quiescent cells, and 48 ms for engaged-CD59-cluster rafts, in cholesterol- and GPI-anchoring-dependent manners.	GPI 1046	227-230	CD59 molecule (CD59 blood group)	Homo sapiens	290-294
27043189-4	2016	Single-fluorescent-molecule imaging in the live-cell plasma membrane revealed the clear but transient colocalization and codiffusion of fluorescent ganglioside analogs with a fluorescently labeled glycosylphosphatidylinisotol (GPI)-anchored protein, human CD59, with lifetimes of 12 ms for CD59 monomers, 40 ms for CD59"s transient homodimer rafts in quiescent cells, and 48 ms for engaged-CD59-cluster rafts, in cholesterol- and GPI-anchoring-dependent manners.	GPI 1046	227-230	CD59 molecule (CD59 blood group)	Homo sapiens	290-294
30873462-6	2016	Results: The rate of CHO oxidation during exercise was significantly higher during 120%LT in relation to 80%LT and CON (18.2 +- 5.6 vs. 9.5 +- 2.7 vs. 1.1 +- 0.4 mg min-1), the absolute rate of fat oxidation was significantly higher in 120%LT compared to 80%LT and CON during exercise (13.5 +- 3.3, 9.5 +- 2.2, and 0.7 +- 0.2 mg min-1, respectively, p &lt; 0.05).	CAV protocol	21-24	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
30873462-6	2016	Results: The rate of CHO oxidation during exercise was significantly higher during 120%LT in relation to 80%LT and CON (18.2 +- 5.6 vs. 9.5 +- 2.7 vs. 1.1 +- 0.4 mg min-1), the absolute rate of fat oxidation was significantly higher in 120%LT compared to 80%LT and CON during exercise (13.5 +- 3.3, 9.5 +- 2.2, and 0.7 +- 0.2 mg min-1, respectively, p &lt; 0.05).	CAV protocol	21-24	CD59 molecule (CD59 blood group)	Homo sapiens	329-334
26890495-4	2016	We analyzed the outcomes of 83 consecutive bortezomib-treated patients with severe RF (eGFR &lt; 30 ml/min/1.73 m(2) ), of which 31 (37%) required dialysis.	Bortezomib	43-53	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
26053785-8	2016	Creatinine at 1 year increased by 0.121 mg/dL, which represents a 12.99% decrease in renal function from baseline (preoperative creatinine 0.823 mg/dL, estimated glomerular filtration rate = 93.9 mL/min/1.73 m(2) ).	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
26965142-3	2016	The data showed that aqueous solutions of the unprotonated form of tetracaine displayed a significantly higher (p&lt;0.05) passive membrane transport compared to solutions with mixtures of the unprotonated and protonated drug microspecies (e.g. transport through the skin was 0.96+-0.31mugcm(-2)min(-1) and 1.59+-0.26mugcm(-2)min(-1) respectively).	Tetracaine	67-77	CD59 molecule (CD59 blood group)	Homo sapiens	295-301
26965142-3	2016	The data showed that aqueous solutions of the unprotonated form of tetracaine displayed a significantly higher (p&lt;0.05) passive membrane transport compared to solutions with mixtures of the unprotonated and protonated drug microspecies (e.g. transport through the skin was 0.96+-0.31mugcm(-2)min(-1) and 1.59+-0.26mugcm(-2)min(-1) respectively).	Tetracaine	67-77	CD59 molecule (CD59 blood group)	Homo sapiens	326-332
26953564-1	2016	OBJECTIVE: The aim of this study was to assess gadolinium deposition in the skin of a patient with normal renal function, based on estimated glomerular filtration rate values greater than 59 mL/min/1.73 m(2) after exposure to large cumulative doses of gadolinium-based contrast agents (GBCAs).	Gadolinium	47-57	CD59 molecule (CD59 blood group)	Homo sapiens	194-199
26960001-11	2016	At 100 muL min(-1) and 60 C, the lauryl methacrylate columns provided the best separation, but their low permeability prevented high flow rates.	dodecyl methacrylate	33-52	CD59 molecule (CD59 blood group)	Homo sapiens	11-17
26960001-12	2016	Flow rates up to 500 muL min(-1) were possible in the styrene, butyl and hexyl methacrylate columns.	Styrene	54-61	CD59 molecule (CD59 blood group)	Homo sapiens	25-31
26960001-12	2016	Flow rates up to 500 muL min(-1) were possible in the styrene, butyl and hexyl methacrylate columns.	butyl and hexyl methacrylate	63-91	CD59 molecule (CD59 blood group)	Homo sapiens	25-31
27196444-4	2016	Laboratory tests showed serum creatinine at 2.3 mg/dL with an estimated glomerular filtration rate of 26 mL/min/1.73m, and gamma-glutamyl transpeptidase and alkaline phosphatase at 3 and 1.5 times the upper normal limit.	Creatinine	30-40	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
26764055-8	2016	Furthermore, LBPP application attenuated LSR by ~0.07-0.28 mg min(-1) cm(-2) during the last 30 min of recovery at all sites except the forehead compared with natural recovery (all P &lt; 0.05).	lbpp	13-17	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
26878357-9	2016	Although mean eGFR declined by 4.2 ml/min/1.73 m(2) within the first week of dapagliflozin therapy, thereafter eGFR gradually recovered to baseline levels by 104 weeks (mean change from baseline +0.02 mL/min/1.73 m(2); 95%CI: -0.9, 1.0).	dapagliflozin	77-90	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
26878357-9	2016	Although mean eGFR declined by 4.2 ml/min/1.73 m(2) within the first week of dapagliflozin therapy, thereafter eGFR gradually recovered to baseline levels by 104 weeks (mean change from baseline +0.02 mL/min/1.73 m(2); 95%CI: -0.9, 1.0).	dapagliflozin	77-90	CD59 molecule (CD59 blood group)	Homo sapiens	204-209
26615797-4	2016	The reaction rate of sonocatalyzed decolorization using MgO nanostructures (12.7 x 10(-3) min(-1)) was more efficient than that of ultrasound alone (2.0 x 10(-3) min(-1)).	Magnesium Oxide	56-59	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
26615797-4	2016	The reaction rate of sonocatalyzed decolorization using MgO nanostructures (12.7 x 10(-3) min(-1)) was more efficient than that of ultrasound alone (2.0 x 10(-3) min(-1)).	Magnesium Oxide	56-59	CD59 molecule (CD59 blood group)	Homo sapiens	162-168
26615797-6	2016	The presence of periodate ions substantially increased the decolorization rate from 14.76 x 10(-3) to 33.4 x 10(-3) min(-1).	metaperiodate	16-25	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
26615797-7	2016	Although the application of aeration favored the decolorization rate (17.8 x 10(-3) min(-1)), the addition of hydrogen peroxide resulted in a considerable decrease in the decolorization rate (9.5 x 10(-3) min(-1)) due to its scavenging effects at specific concentrations.	Hydrogen Peroxide	110-127	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
26615797-7	2016	Although the application of aeration favored the decolorization rate (17.8 x 10(-3) min(-1)), the addition of hydrogen peroxide resulted in a considerable decrease in the decolorization rate (9.5 x 10(-3) min(-1)) due to its scavenging effects at specific concentrations.	Hydrogen Peroxide	110-127	CD59 molecule (CD59 blood group)	Homo sapiens	205-211
26960444-9	2016	FatOx decreased after the CHO-rich diet compared with the habitual day 2 (from 0.42 +- 0.15 to 0.29 +- 0.13 g min(-1), p &lt; 0.05).	CAV protocol	26-29	CD59 molecule (CD59 blood group)	Homo sapiens	110-116
26932178-5	2016	Mean adjusted estimated glomerular filtration rate (GFR) at year 5 in LDKT recipients was 67.2 vs. 60.8 mL/min/1.73m2 for everolimus vs. cyclosporine (mean difference 6.4 mL/min/1.73m2; p = 0.031).	Everolimus	122-132	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
26767705-6	2016	RESULTS:  RESULTS: At day 0, 3 mug kg-1 min-1) dopamine did not increase mean renal blood flow over baseline (580 mL/min [219-663 mL/min] vs 542 mL/min [207-686 mL/min]; P = .84).	Dopamine	47-55	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
26767705-9	2016	At day 6, 3 mug kg-1 min-1 dopamine increased mean renal blood flow over baseline (318 mL/min [234-897 mL/min] vs 191 mL/min [173-706 mL/min]; P = .016), with no further increase at higher doses.	Dopamine	27-35	CD59 molecule (CD59 blood group)	Homo sapiens	21-26
27752611-7	2016	In the maintenance phase, the norepinephrine dose was 0.37+-0.57 and 0.26+-0.91 microg kg-1 min-1 in the 33 C and 36 C TTM groups, respectively (P&lt;0.01).	Norepinephrine	30-44	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
27752611-8	2016	During the rewarming phase, the norepinephrine and dopamine doses were 0.49+-0.60 and 9.67+-9.60 mcg kg-1 min-1 in the 33 C TTM group and 0.14+-0.46 and 3.13+-7.19 mcg kg-1 min-1 in the 36 C TTM group, respectively (P&lt;0.01).	Norepinephrine	32-46	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
27752611-8	2016	During the rewarming phase, the norepinephrine and dopamine doses were 0.49+-0.60 and 9.67+-9.60 mcg kg-1 min-1 in the 33 C TTM group and 0.14+-0.46 and 3.13+-7.19 mcg kg-1 min-1 in the 36 C TTM group, respectively (P&lt;0.01).	Dopamine	51-59	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
26890152-4	2016	These adjustments resulted in an increase of the silica surface area from 391 to 798 m(2) g(-1), which leads to a high capacity (686 mg g(-1)) of D4-capture for the silica synthesized at 80  C, calcined at 450  C with the heating rate of 100  C min(-1) (Si-Syn80).	Silicon Dioxide	49-55	CD59 molecule (CD59 blood group)	Homo sapiens	245-251
26890152-4	2016	These adjustments resulted in an increase of the silica surface area from 391 to 798 m(2) g(-1), which leads to a high capacity (686 mg g(-1)) of D4-capture for the silica synthesized at 80  C, calcined at 450  C with the heating rate of 100  C min(-1) (Si-Syn80).	Silicon Dioxide	165-171	CD59 molecule (CD59 blood group)	Homo sapiens	245-251
26890152-6	2016	Recyclability tests on the commercial silica gel and mesoporous silica synthesized at 120  C and calcined at 450  C with a heating rate of 100  C min(-1) (called Si-Syn120 or Si-450 or Si-100  C min(-1)) indicated that the Si-Syn120 (capacity drop 10%) is more efficient than silica gel (capacity drop 15%) after three cycles.	Silicon	162-164	CD59 molecule (CD59 blood group)	Homo sapiens	146-152
26938062-5	2016	Using chitosan as the substrate, the optimal pH for the enzyme reaction was 4.5; the kinetic parameters Km and Vmax were 0.089 mg mL-1 and 0.69 mumol min-1 mg-1, respectively.	Chitosan	6-14	CD59 molecule (CD59 blood group)	Homo sapiens	150-160
27857961-4	2016	Compared to Control, Pre-Sago resulted in a smaller rise in rectal temperature (0.3 +- 0.5 C) while heart rate increased to a greater extent (6 +- 13 beats min-1) during exercise (both P &lt; 0.05), however, compared to Control time-trial performance remained unaffected (Pre-Sago: -0.5 +- 4.0%, P &gt; 0.05).	sago	25-29	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
26647444-5	2016	nNO (30 nL min(-1) cut-off) had good sensitivity and specificity (91% and 96%, respectively).	Nitrous Oxide	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	11-17
27033452-10	2016	Atropine attenuated sweating as assessed using the new (control: 0.87 +- 0.23 mg min(-1) cm(-2)vs. atropine: 0.54 +- 0.22 mg min(-1) cm(-2);P &lt; 0.01) and classic (control: 0.85 +- 0.33 mg min(-1) cm(-2)vs. atropine: 0.60 +- 0.26 mg min(-1) cm(-2);P = 0.05) capsule designs.	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
27033452-10	2016	Atropine attenuated sweating as assessed using the new (control: 0.87 +- 0.23 mg min(-1) cm(-2)vs. atropine: 0.54 +- 0.22 mg min(-1) cm(-2);P &lt; 0.01) and classic (control: 0.85 +- 0.33 mg min(-1) cm(-2)vs. atropine: 0.60 +- 0.26 mg min(-1) cm(-2);P = 0.05) capsule designs.	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	125-131
27033452-10	2016	Atropine attenuated sweating as assessed using the new (control: 0.87 +- 0.23 mg min(-1) cm(-2)vs. atropine: 0.54 +- 0.22 mg min(-1) cm(-2);P &lt; 0.01) and classic (control: 0.85 +- 0.33 mg min(-1) cm(-2)vs. atropine: 0.60 +- 0.26 mg min(-1) cm(-2);P = 0.05) capsule designs.	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	125-131
27033452-10	2016	Atropine attenuated sweating as assessed using the new (control: 0.87 +- 0.23 mg min(-1) cm(-2)vs. atropine: 0.54 +- 0.22 mg min(-1) cm(-2);P &lt; 0.01) and classic (control: 0.85 +- 0.33 mg min(-1) cm(-2)vs. atropine: 0.60 +- 0.26 mg min(-1) cm(-2);P = 0.05) capsule designs.	Atropine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	125-131
26765360-3	2016	15 mg L(-1) of ferric chloride provided the greatest enhancement of approximately 10-fold, using 20% acetic acid combined with 4% formic acid with 30 s ultraviolet irradiation at 200 mL min(-1) Ar/H2 flow rate.	ferric chloride	15-30	CD59 molecule (CD59 blood group)	Homo sapiens	186-192
26744210-5	2016	RESULTS: Arterial pO2 levels increased significantly (ANOVA, p &lt; 0.05) with SOF: 13.9 +- 1.2 (0 L min(-1)); 18.5 +- 1.5 (5 L min(-1)); 21.7 +- 1.7 (10 L min(-1)); 24.0 +- 2.3 (15 L min(-1)).	PO-2	18-21	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
26842652-7	2016	An increase of 100 mumol/L baseline uric acid level resulted in a decrease of 5.684 ml/min/1.73 m(2) in eGFR [95% confidence interval (CI): 7.735-3.633].	Uric Acid	36-45	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
26802381-7	2016	Continuous oxygen at 2 L   min-1 via nasal cannula corrected the hypoxia, although P(a)co(2) increased to 6.9 kPa with reduction in pH to the threshold of severe respiratory acidosis (pH 7.25).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
26477665-3	2016	The decrease in serum bicarbonate concentration is usually absent until glomerular filtration rate decreases to &lt;20 to 25mL/min/1.73 m(2), although it can develop with lesser degrees of decreased kidney function.	Bicarbonates	22-33	CD59 molecule (CD59 blood group)	Homo sapiens	127-132
26519800-4	2016	The average first order photo-degradation rate constants in the absence and presence of 500 mM fructose were 0.92 and 2.07 min(-1) respectively for diuron and 0.04 and 0.07 min(-1) for chlorpyrifos.	Fructose	95-103	CD59 molecule (CD59 blood group)	Homo sapiens	123-129
26519800-4	2016	The average first order photo-degradation rate constants in the absence and presence of 500 mM fructose were 0.92 and 2.07 min(-1) respectively for diuron and 0.04 and 0.07 min(-1) for chlorpyrifos.	Fructose	95-103	CD59 molecule (CD59 blood group)	Homo sapiens	173-179
26519800-4	2016	The average first order photo-degradation rate constants in the absence and presence of 500 mM fructose were 0.92 and 2.07 min(-1) respectively for diuron and 0.04 and 0.07 min(-1) for chlorpyrifos.	Diuron	148-154	CD59 molecule (CD59 blood group)	Homo sapiens	123-129
26519800-4	2016	The average first order photo-degradation rate constants in the absence and presence of 500 mM fructose were 0.92 and 2.07 min(-1) respectively for diuron and 0.04 and 0.07 min(-1) for chlorpyrifos.	Chlorpyrifos	185-197	CD59 molecule (CD59 blood group)	Homo sapiens	173-179
26607244-6	2016	Maximal oxygen consumption in normoxia was 70 +- 2 ml min(-1 )kg(-1) in ATL vs. 43 +- 2 ml min(-1 )kg(-1) in CON, and in hypoxia decreased more in ATL (-41%) than in CON (-25%, P &lt; 0.05).	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	54-60
26607244-6	2016	Maximal oxygen consumption in normoxia was 70 +- 2 ml min(-1 )kg(-1) in ATL vs. 43 +- 2 ml min(-1 )kg(-1) in CON, and in hypoxia decreased more in ATL (-41%) than in CON (-25%, P &lt; 0.05).	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	91-97
26610195-6	2016	In both systems, a pseudo first order reaction was found to provide the best correlations, with constant rates of 2.0 x 10(-2) min(-1) and 2.4 x 10(-2) min(-1) for TiO2 nanowires and P25, respectively.	titanium dioxide	164-168	CD59 molecule (CD59 blood group)	Homo sapiens	152-158
26829612-6	2016	For the in vitro part of this study, EDTA-treated whole blood was irradiated immediately after venipuncture using single X-ray doses (1 Gy/min(-1) dose rate, 100 keV).	Edetic Acid	37-41	CD59 molecule (CD59 blood group)	Homo sapiens	139-145
26725500-6	2016	Notably, the Pt@Ni core-shell NPs with a patch-like Ni layer on Pt cores (0.5 and 1 h) show a higher H2 generation rate of 1221-1475 H2 mL min(-1) g(-1)cat than the Pt@Ni NPs with a thick Ni layer (2 and 4 h, 920-1183 H2 mL min(-1) g(-1)cat), and much higher than that of pure Pt NPs (224 H2 mL min(-1) g(-1)cat).	Hydrogen	101-103	CD59 molecule (CD59 blood group)	Homo sapiens	139-145
26725500-6	2016	Notably, the Pt@Ni core-shell NPs with a patch-like Ni layer on Pt cores (0.5 and 1 h) show a higher H2 generation rate of 1221-1475 H2 mL min(-1) g(-1)cat than the Pt@Ni NPs with a thick Ni layer (2 and 4 h, 920-1183 H2 mL min(-1) g(-1)cat), and much higher than that of pure Pt NPs (224 H2 mL min(-1) g(-1)cat).	Hydrogen	101-103	CD59 molecule (CD59 blood group)	Homo sapiens	224-230
26725500-6	2016	Notably, the Pt@Ni core-shell NPs with a patch-like Ni layer on Pt cores (0.5 and 1 h) show a higher H2 generation rate of 1221-1475 H2 mL min(-1) g(-1)cat than the Pt@Ni NPs with a thick Ni layer (2 and 4 h, 920-1183 H2 mL min(-1) g(-1)cat), and much higher than that of pure Pt NPs (224 H2 mL min(-1) g(-1)cat).	Hydrogen	101-103	CD59 molecule (CD59 blood group)	Homo sapiens	224-230
26592619-11	2016	The detection limits of 1.2 and 1.6mg L(-1) for benomyl and aldicarb were obtained when the separation was performed at 120 C with flow rate of 0.4mL min(-1) water.	Benomyl	48-55	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
26592619-11	2016	The detection limits of 1.2 and 1.6mg L(-1) for benomyl and aldicarb were obtained when the separation was performed at 120 C with flow rate of 0.4mL min(-1) water.	Aldicarb	60-68	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
26592619-11	2016	The detection limits of 1.2 and 1.6mg L(-1) for benomyl and aldicarb were obtained when the separation was performed at 120 C with flow rate of 0.4mL min(-1) water.	Water	158-163	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
26744210-5	2016	RESULTS: Arterial pO2 levels increased significantly (ANOVA, p &lt; 0.05) with SOF: 13.9 +- 1.2 (0 L min(-1)); 18.5 +- 1.5 (5 L min(-1)); 21.7 +- 1.7 (10 L min(-1)); 24.0 +- 2.3 (15 L min(-1)).	PO-2	18-21	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
26744210-5	2016	RESULTS: Arterial pO2 levels increased significantly (ANOVA, p &lt; 0.05) with SOF: 13.9 +- 1.2 (0 L min(-1)); 18.5 +- 1.5 (5 L min(-1)); 21.7 +- 1.7 (10 L min(-1)); 24.0 +- 2.3 (15 L min(-1)).	PO-2	18-21	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
26744210-5	2016	RESULTS: Arterial pO2 levels increased significantly (ANOVA, p &lt; 0.05) with SOF: 13.9 +- 1.2 (0 L min(-1)); 18.5 +- 1.5 (5 L min(-1)); 21.7 +- 1.7 (10 L min(-1)); 24.0 +- 2.3 (15 L min(-1)).	PO-2	18-21	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
26738794-6	2016	Increased internalization of endothelial CD59 in IH appeared to be cholesterol-dependent and was reversed by statins in a CD59-dependent manner.	Cholesterol	67-78	CD59 molecule (CD59 blood group)	Homo sapiens	41-45
26454686-9	2016	RESULTS: Mean iohexol, iothalamate, and creatinine clearances were 52+-28 (SD), 60+-34, and 74+-40 mL/min/1.73 m(2), respectively.	Creatinine	40-50	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
26703262-6	2016	The phase separation was achieved by gentle bubbling of nitrogen stream (2 mL min(-1) during 2 min).	Nitrogen	56-64	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
26055419-4	2016	The estimated glomerular filtration rate (eGFR) decreased significantly in the tenofovir group after a mean of 17 months treatment (from 92.2 to 85.6 mL/min/1.73 m(2), p &lt; 0.001), but increased in the telbivudine group after a mean of 32 months of treatment (from 86.1 to 95 mL/min/1.73 m(2), p &lt; 0.001).	Tenofovir	79-88	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
26055419-4	2016	The estimated glomerular filtration rate (eGFR) decreased significantly in the tenofovir group after a mean of 17 months treatment (from 92.2 to 85.6 mL/min/1.73 m(2), p &lt; 0.001), but increased in the telbivudine group after a mean of 32 months of treatment (from 86.1 to 95 mL/min/1.73 m(2), p &lt; 0.001).	Tenofovir	79-88	CD59 molecule (CD59 blood group)	Homo sapiens	281-286
26793277-8	2016	4-Methoxy-alpha-PVP exhibited a long half-life of 79.7 min in HLM, with an intrinsic clearance of 8.7 microL min-1 mg-1.	4-methoxy-alpha-pyrrolidinovalerophenone	0-19	CD59 molecule (CD59 blood group)	Homo sapiens	109-119
27182420-12	2016	The TAE group significantly increased cardiorespiratory fitness (baseline 47.8+-3.8; post 49.1+-3.1 ml kg-1 min-1; p = 0.023) with no change in the SGA group (baseline 46.3+-3.5; post 47.2+-2.7 ml kg-1 min-1; p = 0.127).	tae	4-7	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
27182420-12	2016	The TAE group significantly increased cardiorespiratory fitness (baseline 47.8+-3.8; post 49.1+-3.1 ml kg-1 min-1; p = 0.023) with no change in the SGA group (baseline 46.3+-3.5; post 47.2+-2.7 ml kg-1 min-1; p = 0.127).	tae	4-7	CD59 molecule (CD59 blood group)	Homo sapiens	202-207
26197030-8	2016	The rate of muscle glycogen degradation during Run 2 was higher with H-CHO (3.1 +- 1.5 mmol   kg dry mass(-1)   min(-1)) than with L-CHO (1.6 +- 1.3 mmol   kg dry mass(-1)   min(-1); P = 0.05).	Glycogen	19-27	CD59 molecule (CD59 blood group)	Homo sapiens	112-118
26197030-8	2016	The rate of muscle glycogen degradation during Run 2 was higher with H-CHO (3.1 +- 1.5 mmol   kg dry mass(-1)   min(-1)) than with L-CHO (1.6 +- 1.3 mmol   kg dry mass(-1)   min(-1); P = 0.05).	h-cho	69-74	CD59 molecule (CD59 blood group)	Homo sapiens	112-118
25787778-5	2015	Levels of tHcy were positively related to PWV measured 4-5 years later for participants with early-stage CKD (estimated glomerular filtration rate &lt;60 ml min(-1) per 1.73 m(2)).	thcy	10-14	CD59 molecule (CD59 blood group)	Homo sapiens	157-163
26839613-8	2015	Carbohydrate oxidation decreased from baseline (1.59 +- 0.4 g min(-1)) to 12 h after CON and ECC (1.36 +- 0.4 g min(-1); p = 0.03).	Carbohydrates	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
26839613-8	2015	Carbohydrate oxidation decreased from baseline (1.59 +- 0.4 g min(-1)) to 12 h after CON and ECC (1.36 +- 0.4 g min(-1); p = 0.03).	Carbohydrates	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	112-118
26014304-4	2015	Acute kidney injury was diagnosed within three days of life when the creatinine clearance was &lt;=16 mL/min/1.73 m2.	Creatinine	69-79	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
26233732-9	2015	Mean eGFR in the febuxostat group showed a nonsignificant increase from 31.5+-13.6 (SD) to 34.7+-18.1mL/min/1.73m(2) at 6 months.	Febuxostat	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
26667947-4	2015	In this report we describe a case of percutaneous transluminal angioplasty of an occluded left superficial femoral artery using CO2as contrast medium, because of severe chronic kidney disease (glomerular filtration rate 28 ml/min/1.73 m2).	co2as	128-133	CD59 molecule (CD59 blood group)	Homo sapiens	226-231
26705203-7	2015	The corresponding tendency of higher anion gap in metformin users with the estimated glomerular filtration rate &gt;60 mL/min/1.73 m was also observed.	Metformin	50-59	CD59 molecule (CD59 blood group)	Homo sapiens	122-127
26185050-8	2015	The overall adjusted change in decline in renal function per unit increase in baseline UA was 0.08 (95% CI -0.01; 0.17) mL/min/1.73 m(2) per year indicating no association between higher UA levels and decline in renal function.	Uric Acid	87-89	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
26590127-6	2015	RESULTS: While adjusting for demographics, cotinine, prehypertension, insulin resistance, body mass index, and hypercholesterolemia, adolescents in the highest PFOA and PFOS quartile had a lower eGFR, 6.84 mL/min/1.73 m(2) (95% CI: 2.19 to 11.48) and 9.69 mL/min/1.73 m(2) (95 % CI: -4.59 to 14.78), respectively, compared to the lowest quartile.	perfluorooctanoic acid	160-164	CD59 molecule (CD59 blood group)	Homo sapiens	209-214
26590127-6	2015	RESULTS: While adjusting for demographics, cotinine, prehypertension, insulin resistance, body mass index, and hypercholesterolemia, adolescents in the highest PFOA and PFOS quartile had a lower eGFR, 6.84 mL/min/1.73 m(2) (95% CI: 2.19 to 11.48) and 9.69 mL/min/1.73 m(2) (95 % CI: -4.59 to 14.78), respectively, compared to the lowest quartile.	perfluorooctanoic acid	160-164	CD59 molecule (CD59 blood group)	Homo sapiens	259-264
26539840-4	2015	During dip coating at a substrate withdrawal speed of 50 cm min(-1) in a thermostatic oven at 60  C, linearly arranged cell-like patterns on a micrometer scale were spontaneously formed on the titania gel films, irrespective of the composition of coating solutions.	3,5-diisopropylsalicylic acid	7-10	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
31973370-3	2015	The cathode assembly consisting of 54 atom % Pt showed enhanced reactivity both in binary (Pt-Pd; k1  10.7x10-3  min-1 ) and ternary (Cu-Pt-Pd; k1  28.6x10-3  min-1 ) states.	Platinum	45-47	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
31973370-3	2015	The cathode assembly consisting of 54 atom % Pt showed enhanced reactivity both in binary (Pt-Pd; k1  10.7x10-3  min-1 ) and ternary (Cu-Pt-Pd; k1  28.6x10-3  min-1 ) states.	Platinum	45-47	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
25297344-5	2015	RESULTS: Maximal HR (HRmax) was greater with caffeine (192 +- 2 vs. 190 +- 2 beat min(-1), p &lt; 0.05).	Caffeine	45-53	CD59 molecule (CD59 blood group)	Homo sapiens	82-88
25806469-5	2015	At Cox regression analysis, uric acid was an independent predictor of 1-year postdischarge mortality (hazard ratio 1.26, 95% confidence interval 1.06-1.51, P = 0.011).In STEMI patients with estimated glomerular filtration rate below 60 ml/min/1.73 m treated with PCI, uric acid helps in identifying a subset of patients at a higher risk of bleeding and acute kidney injury.	Uric Acid	28-37	CD59 molecule (CD59 blood group)	Homo sapiens	239-244
26373645-10	2015	To conclude, ingesting 0.5-1.0:1-ratio fructose:glucose/maltodextrin beverages at 1.3-2.4 g min(-1) likely benefits 2.5-3.0 h endurance power versus isocaloric single saccharide.	Fructose	39-47	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
26373645-10	2015	To conclude, ingesting 0.5-1.0:1-ratio fructose:glucose/maltodextrin beverages at 1.3-2.4 g min(-1) likely benefits 2.5-3.0 h endurance power versus isocaloric single saccharide.	Glucose	48-55	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
26373645-10	2015	To conclude, ingesting 0.5-1.0:1-ratio fructose:glucose/maltodextrin beverages at 1.3-2.4 g min(-1) likely benefits 2.5-3.0 h endurance power versus isocaloric single saccharide.	maltodextrin	56-68	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
26464000-3	2015	Patients in group D received continuous intravenous infusion of DEX 0.8 mug   kg-1   min-1 after the induction.	Dexmedetomidine	64-67	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
26291542-10	2015	Peak oxygen uptake increased 1.1 (0.4-1.7) ml min(-1) kg(-1) (8%) from baseline (P&lt;0.01).	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	46-52
25663351-7	2015	The annual estimated glomerular filtration rate change was -3.83 mL/min/1.73 m(2) in the tolvaptan group and -5.05 mL in the placebo group for a treatment effect of +1.22 mL/min/1.73 m(2) (95 % CI 0.41-2.02: P = 0.003).	Tolvaptan	89-98	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
26459721-8	2015	Everolimus initiation with CNIs elimination improved glomerular filtration rate (GFR, measured with the modification of diet in renal disease formula) of 10.42 mL/min/1.73 m2 (95% CI: 3.44-17.41; P&lt;0.01) one year after treatment, but increased tBPAR (RR: 1.71; 95% CI: 1.15-2.53; P&lt;0.01).	Everolimus	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
25975191-6	2015	Importantly, all-trans retinoic acid (ATRA) increased CD38 expression levels but also reduced expression of the complement-inhibitory proteins CD55 and CD59 in both cell lines and primary MM samples.	Tretinoin	13-36	CD59 molecule (CD59 blood group)	Homo sapiens	152-156
25975191-6	2015	Importantly, all-trans retinoic acid (ATRA) increased CD38 expression levels but also reduced expression of the complement-inhibitory proteins CD55 and CD59 in both cell lines and primary MM samples.	Tretinoin	38-42	CD59 molecule (CD59 blood group)	Homo sapiens	152-156
25877916-8	2015	Our data suggest that the widely used estimated baseline creatinine clearance value of 120 mL/min/1.73 m(2) underestimates actual baseline function in patients admitted to paediatric intensive care units.	Creatinine	57-67	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
26053965-6	2015	The maximum flow rates and pressures generated by the pump using DI water as a working buffer are 10 nL min(-1) and 30 Pa, respectively.	Water	65-73	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
26338686-8	2015	Prevalence of eGFR &lt;60 mL/min/1.73 m(2) among metformin initiators was 9.0% in Denmark and 25.2% in the UK.	Metformin	49-58	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
26338686-9	2015	In contrast, prevalence of eGFR values &lt;30 mL/min/1.73 m(2) among metformin initiators was 0.3% in Denmark and 0.4% in the UK.	Metformin	69-78	CD59 molecule (CD59 blood group)	Homo sapiens	49-54
26338686-12	2015	The proportion of patients continuing metformin use, even after a first decline brought the eGFR below 30 mL/min/1.73 m(2), was 44% in Denmark and 62% in the UK.	Metformin	38-47	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
26962611-4	2015	Canagliflozin is contraindicated in renally impaired patients who have an eGFR of less than 45 mL/min/1.73 m(2), have end-stage renal disease, or are on dialysis.	Canagliflozin	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	98-103
26358343-5	2015	RESULTS: Carbachol-stimulated secretion rates were the following: controls, 1670 +- 381 pl min(-1) gland(-1); CRS, 965 +- 440 pl min(-1) gland(-1); and CF, 933 +- 588 pl min(-1) gland(-1) (p = 0.23, Kruskal-Wallis test).	Carbachol	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	91-97
26358343-5	2015	RESULTS: Carbachol-stimulated secretion rates were the following: controls, 1670 +- 381 pl min(-1) gland(-1); CRS, 965 +- 440 pl min(-1) gland(-1); and CF, 933 +- 588 pl min(-1) gland(-1) (p = 0.23, Kruskal-Wallis test).	Carbachol	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
26358343-5	2015	RESULTS: Carbachol-stimulated secretion rates were the following: controls, 1670 +- 381 pl min(-1) gland(-1); CRS, 965 +- 440 pl min(-1) gland(-1); and CF, 933 +- 588 pl min(-1) gland(-1) (p = 0.23, Kruskal-Wallis test).	Carbachol	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
26358343-6	2015	Forskolin-stimulated secretion rates were the following: controls, 229 +- 14 pl min(-1) gland(-1); CRS, 154 +- 48 pl min(-1) gland(-1); and CF, 22 +- 15 pl min(-1) gland(-1) (p = 0.008, Kruskal-Wallis test).	Colforsin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	80-86
26358343-6	2015	Forskolin-stimulated secretion rates were the following: controls, 229 +- 14 pl min(-1) gland(-1); CRS, 154 +- 48 pl min(-1) gland(-1); and CF, 22 +- 15 pl min(-1) gland(-1) (p = 0.008, Kruskal-Wallis test).	Colforsin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
26358343-6	2015	Forskolin-stimulated secretion rates were the following: controls, 229 +- 14 pl min(-1) gland(-1); CRS, 154 +- 48 pl min(-1) gland(-1); and CF, 22 +- 15 pl min(-1) gland(-1) (p = 0.008, Kruskal-Wallis test).	Colforsin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
25919658-4	2015	Patients who received dexmedetomidine, compared with saline after 20 min, had a lower mean (SD) heart rate (56.7 (5.2) vs. 67.1 (7.1) beats.min(-1) ), higher systolic blood pressure (125.7 (18.9) vs. 109 (7.9) mmHg), and lower cardiac output (2.9 (0.5) vs. 3.7 (1.0) l.min(-1) ), respectively (all p &lt; 0.05).	Dexmedetomidine	22-37	CD59 molecule (CD59 blood group)	Homo sapiens	140-147
25919658-4	2015	Patients who received dexmedetomidine, compared with saline after 20 min, had a lower mean (SD) heart rate (56.7 (5.2) vs. 67.1 (7.1) beats.min(-1) ), higher systolic blood pressure (125.7 (18.9) vs. 109 (7.9) mmHg), and lower cardiac output (2.9 (0.5) vs. 3.7 (1.0) l.min(-1) ), respectively (all p &lt; 0.05).	Dexmedetomidine	22-37	CD59 molecule (CD59 blood group)	Homo sapiens	269-276
26033571-1	2015	The glycolipid glycosylphosphatidylinositol anchor (GPI-A) plays an important role in lipid raft formation, which is required for proper expression on the cell surface of two inhibitors of the complement cascade, CD55 and CD59.	Glycolipids	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	222-226
26033571-1	2015	The glycolipid glycosylphosphatidylinositol anchor (GPI-A) plays an important role in lipid raft formation, which is required for proper expression on the cell surface of two inhibitors of the complement cascade, CD55 and CD59.	Glycosylphosphatidylinositols	15-43	CD59 molecule (CD59 blood group)	Homo sapiens	222-226
26056328-4	2015	After 2008, gemcitabine and cisplatin was the most frequently used regimen in patients with an estimated glomerular filtration rate &lt; 60 ml/min/1.73 m(2) and in those with estimated glomerular filtration rate &gt;= 60 ml/min/1.73 m(2).	gemcitabine	12-23	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
26056328-4	2015	After 2008, gemcitabine and cisplatin was the most frequently used regimen in patients with an estimated glomerular filtration rate &lt; 60 ml/min/1.73 m(2) and in those with estimated glomerular filtration rate &gt;= 60 ml/min/1.73 m(2).	gemcitabine	12-23	CD59 molecule (CD59 blood group)	Homo sapiens	224-229
26056328-4	2015	After 2008, gemcitabine and cisplatin was the most frequently used regimen in patients with an estimated glomerular filtration rate &lt; 60 ml/min/1.73 m(2) and in those with estimated glomerular filtration rate &gt;= 60 ml/min/1.73 m(2).	Cisplatin	28-37	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
26056328-4	2015	After 2008, gemcitabine and cisplatin was the most frequently used regimen in patients with an estimated glomerular filtration rate &lt; 60 ml/min/1.73 m(2) and in those with estimated glomerular filtration rate &gt;= 60 ml/min/1.73 m(2).	Cisplatin	28-37	CD59 molecule (CD59 blood group)	Homo sapiens	224-229
26056328-6	2015	Gemcitabine and cisplatin demonstrated a better 3-year overall survival when the estimated glomerular filtration rate was &gt;= 60 ml/min/1.73 m(2) (31.4%), but it tended to be worse when the estimated glomerular filtration rate was &lt; 60 ml/min/1.73 m(2) (14.1%).	gemcitabine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
26056328-6	2015	Gemcitabine and cisplatin demonstrated a better 3-year overall survival when the estimated glomerular filtration rate was &gt;= 60 ml/min/1.73 m(2) (31.4%), but it tended to be worse when the estimated glomerular filtration rate was &lt; 60 ml/min/1.73 m(2) (14.1%).	gemcitabine	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	244-249
26056328-6	2015	Gemcitabine and cisplatin demonstrated a better 3-year overall survival when the estimated glomerular filtration rate was &gt;= 60 ml/min/1.73 m(2) (31.4%), but it tended to be worse when the estimated glomerular filtration rate was &lt; 60 ml/min/1.73 m(2) (14.1%).	Cisplatin	16-25	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
26056328-6	2015	Gemcitabine and cisplatin demonstrated a better 3-year overall survival when the estimated glomerular filtration rate was &gt;= 60 ml/min/1.73 m(2) (31.4%), but it tended to be worse when the estimated glomerular filtration rate was &lt; 60 ml/min/1.73 m(2) (14.1%).	Cisplatin	16-25	CD59 molecule (CD59 blood group)	Homo sapiens	244-249
26056328-8	2015	Among the patients with estimated glomerular filtration rate &lt; 60 ml/min/1.73 m(2), the 1-year overall survival of the patients treated with a reduced dose of gemcitabine and cisplatin was significantly lower than that of those treated with standard-dose gemcitabine and cisplatin (26.2 vs. 60.3%, respectively, P = 0.0108).	gemcitabine	162-173	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
26056328-8	2015	Among the patients with estimated glomerular filtration rate &lt; 60 ml/min/1.73 m(2), the 1-year overall survival of the patients treated with a reduced dose of gemcitabine and cisplatin was significantly lower than that of those treated with standard-dose gemcitabine and cisplatin (26.2 vs. 60.3%, respectively, P = 0.0108).	Cisplatin	178-187	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
26056328-9	2015	CONCLUSIONS: Gemcitabine and cisplatin provided favorable responses and survival in patients with estimated glomerular filtration rate &gt;= 60 ml/min/1.73 m(2) but unsatisfactory oncological outcomes in patients with estimated glomerular filtration rate &lt; 60 ml/min/1.73 m(2), especially when treated with a reduced dose.	gemcitabine	13-24	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
26056328-9	2015	CONCLUSIONS: Gemcitabine and cisplatin provided favorable responses and survival in patients with estimated glomerular filtration rate &gt;= 60 ml/min/1.73 m(2) but unsatisfactory oncological outcomes in patients with estimated glomerular filtration rate &lt; 60 ml/min/1.73 m(2), especially when treated with a reduced dose.	gemcitabine	13-24	CD59 molecule (CD59 blood group)	Homo sapiens	266-271
26056328-9	2015	CONCLUSIONS: Gemcitabine and cisplatin provided favorable responses and survival in patients with estimated glomerular filtration rate &gt;= 60 ml/min/1.73 m(2) but unsatisfactory oncological outcomes in patients with estimated glomerular filtration rate &lt; 60 ml/min/1.73 m(2), especially when treated with a reduced dose.	Cisplatin	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	147-152
26056328-9	2015	CONCLUSIONS: Gemcitabine and cisplatin provided favorable responses and survival in patients with estimated glomerular filtration rate &gt;= 60 ml/min/1.73 m(2) but unsatisfactory oncological outcomes in patients with estimated glomerular filtration rate &lt; 60 ml/min/1.73 m(2), especially when treated with a reduced dose.	Cisplatin	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	266-271
26442411-14	2015	Remifentanil was increased up to 1 mug x kg(-1) x min(-1).	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	50-56
25818314-1	2015	CD59 encodes a 77 amino acid glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that inhibits the final step of membrane attack complex (MAC) formation.	amino acid glycosylphosphatidylinositol	18-57	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
25818314-1	2015	CD59 encodes a 77 amino acid glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that inhibits the final step of membrane attack complex (MAC) formation.	Glycosylphosphatidylinositols	59-62	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
26274605-7	2015	The rate constants for BDE-47 and BDE-28 (9.01 and 17.52 x 10-3 min-1), added to isopropyl alcohol, were very close to those (9.65 and 18.42 x 10-3 min-1) in water, proving the less indirect photolytic contribution of  OH in water.	2-Propanol	81-98	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
26274605-7	2015	The rate constants for BDE-47 and BDE-28 (9.01 and 17.52 x 10-3 min-1), added to isopropyl alcohol, were very close to those (9.65 and 18.42 x 10-3 min-1) in water, proving the less indirect photolytic contribution of  OH in water.	2-Propanol	81-98	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
26274605-7	2015	The rate constants for BDE-47 and BDE-28 (9.01 and 17.52 x 10-3 min-1), added to isopropyl alcohol, were very close to those (9.65 and 18.42 x 10-3 min-1) in water, proving the less indirect photolytic contribution of  OH in water.	Water	158-163	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
26274605-7	2015	The rate constants for BDE-47 and BDE-28 (9.01 and 17.52 x 10-3 min-1), added to isopropyl alcohol, were very close to those (9.65 and 18.42 x 10-3 min-1) in water, proving the less indirect photolytic contribution of  OH in water.	Water	158-163	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
26274605-7	2015	The rate constants for BDE-47 and BDE-28 (9.01 and 17.52 x 10-3 min-1), added to isopropyl alcohol, were very close to those (9.65 and 18.42 x 10-3 min-1) in water, proving the less indirect photolytic contribution of  OH in water.	Water	225-230	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
26274605-7	2015	The rate constants for BDE-47 and BDE-28 (9.01 and 17.52 x 10-3 min-1), added to isopropyl alcohol, were very close to those (9.65 and 18.42 x 10-3 min-1) in water, proving the less indirect photolytic contribution of  OH in water.	Water	225-230	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
25902552-5	2015	CHO oxidation rate during the constant load exercise at 65% of VO2max was elevated in high CHO diet (1.05 +- 0.38 g min-1) compared with low CHO diet (0.63 +- 0.36 g min-1).	CAV protocol	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
25902552-5	2015	CHO oxidation rate during the constant load exercise at 65% of VO2max was elevated in high CHO diet (1.05 +- 0.38 g min-1) compared with low CHO diet (0.63 +- 0.36 g min-1).	CAV protocol	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
25902552-5	2015	CHO oxidation rate during the constant load exercise at 65% of VO2max was elevated in high CHO diet (1.05 +- 0.38 g min-1) compared with low CHO diet (0.63 +- 0.36 g min-1).	CAV protocol	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
25902552-5	2015	CHO oxidation rate during the constant load exercise at 65% of VO2max was elevated in high CHO diet (1.05 +- 0.38 g min-1) compared with low CHO diet (0.63 +- 0.36 g min-1).	CAV protocol	91-94	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
26271970-0	2015	[Mutation of palmitoylation site of linker for activation of T cells inhibits signal transduction mediated by glycosyl phosphatidyl inositol-anchored CD59 in T cells].	Glycosylphosphatidylinositols	110-140	CD59 molecule (CD59 blood group)	Homo sapiens	150-154
28793435-5	2015	They provide an initial turnover frequency (TOF) value of 80 min-1 in hydrogen generation from the hydrolysis of ammonia-borane at room temperature.	Hydrogen	70-78	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
28793435-5	2015	They provide an initial turnover frequency (TOF) value of 80 min-1 in hydrogen generation from the hydrolysis of ammonia-borane at room temperature.	Ammonia borane	113-127	CD59 molecule (CD59 blood group)	Homo sapiens	61-66
25982133-5	2015	RESULTS: The endogenous mean baseline cortisol production was 7.9 (SE 1.5) nM min(-1).	Hydrocortisone	38-46	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
25982133-6	2015	Consistent with the circadian rhythm, cortisol production decayed by 1.25 nM min(-1) h(-1).	Hydrocortisone	38-46	CD59 molecule (CD59 blood group)	Homo sapiens	77-83
25909687-9	2015	When using urine osmolality to adjust for urine concentration, a log-unit increase in total arsenic and DMA was associated with a 0.4 mL/min/1.73 m(2) (95% CI -1.8 to 1.1 mL/min/1.73 m(2)) and 0.01 (95% CI -1.9 to 1.9 mL/min/1.73 m(2)) lower eGFR, respectively.	Arsenic	92-99	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
25909687-9	2015	When using urine osmolality to adjust for urine concentration, a log-unit increase in total arsenic and DMA was associated with a 0.4 mL/min/1.73 m(2) (95% CI -1.8 to 1.1 mL/min/1.73 m(2)) and 0.01 (95% CI -1.9 to 1.9 mL/min/1.73 m(2)) lower eGFR, respectively.	Arsenic	92-99	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
25909687-9	2015	When using urine osmolality to adjust for urine concentration, a log-unit increase in total arsenic and DMA was associated with a 0.4 mL/min/1.73 m(2) (95% CI -1.8 to 1.1 mL/min/1.73 m(2)) and 0.01 (95% CI -1.9 to 1.9 mL/min/1.73 m(2)) lower eGFR, respectively.	Arsenic	92-99	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
25909687-9	2015	When using urine osmolality to adjust for urine concentration, a log-unit increase in total arsenic and DMA was associated with a 0.4 mL/min/1.73 m(2) (95% CI -1.8 to 1.1 mL/min/1.73 m(2)) and 0.01 (95% CI -1.9 to 1.9 mL/min/1.73 m(2)) lower eGFR, respectively.	Cacodylic Acid	104-107	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
25909687-9	2015	When using urine osmolality to adjust for urine concentration, a log-unit increase in total arsenic and DMA was associated with a 0.4 mL/min/1.73 m(2) (95% CI -1.8 to 1.1 mL/min/1.73 m(2)) and 0.01 (95% CI -1.9 to 1.9 mL/min/1.73 m(2)) lower eGFR, respectively.	Cacodylic Acid	104-107	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
25909687-9	2015	When using urine osmolality to adjust for urine concentration, a log-unit increase in total arsenic and DMA was associated with a 0.4 mL/min/1.73 m(2) (95% CI -1.8 to 1.1 mL/min/1.73 m(2)) and 0.01 (95% CI -1.9 to 1.9 mL/min/1.73 m(2)) lower eGFR, respectively.	Cacodylic Acid	104-107	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
25559901-6	2015	Overall, ingestion of MTC led to increased exogenous carbohydrate oxidation, reduced GI distress, and improved performance during cycling lasting &gt;=2.5 hours, particularly when carbohydrate was ingested at &gt;=1.2 g min-1.	mtc	22-25	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
25559901-8	2015	In addition, the majority of the studies fed carbohydrate at &gt;=1.2 g min-1, which may have inflated levels of GI distress and exaggerated performance decrements with single-saccharide feedings.	Carbohydrates	45-57	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
25739396-11	2015	For a 10% RH, the penetration of a wide range of sizes was observed to be higher with the cyclic flow (170 as MIF) than with the equivalent constant flow (170 l min(-1)).	Rhodium	10-12	CD59 molecule (CD59 blood group)	Homo sapiens	161-167
25716637-5	2015	After 12 months, the vitamin D-supplemented group had a change in serum 25OHD +35 versus +6 ng/mL for placebo, P&lt;.001; OGIS +7.8 versus -16.0 mL x min(-1) x m(-2) for placebo, P = .026; and A1C -0.01 versus +0.01% for placebo, P = .66.	Vitamin D	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
26165528-7	2015	RESULTS: While none of the emergency delivery devices performed as well as the head hood, limb tissue oxygenation was greatest when O2 was delivered via the NRB at 15 L min-1.	Oxygen	132-134	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
25700100-6	2015	Caffeine clearance was 0.95+-0.14 mL min(-1) kg(-1) while the elimination half-life of caffeine was 17.63+-8.06 h. Paraxanthine and theophylline levels were significantly elevated at 15 h with no significant change in theobromine.	Caffeine	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	37-43
25612234-7	2015	These analyses provided support for approval of canagliflozin in T2DM patients with baseline eGFR &gt;= 45 mL/min/1.73 m(2) , highlighting a data-driven approach to dose optimization.	Canagliflozin	48-61	CD59 molecule (CD59 blood group)	Homo sapiens	110-115
25725314-3	2015	Because expression of CD55 but not CD46 and CD59 in mesothelial cells was significantly correlated to value of dialysate-to-plasma creatinine concentration ratio (D/P Cre) (p&lt;0.005) as an indicator of peritoneal function, we focused on analysis of CD55 expression of HPMCs in comparison with levels of C activation products in the PDF of the PD patients, and their background factors.	Creatinine	131-141	CD59 molecule (CD59 blood group)	Homo sapiens	44-48
26111694-2	2015	METHODS: Recombinant plasmids for RNA interference of CD59 gene were constructed and transfected into GLC-P cells via lipofectamine 2000.	Lipofectamine	118-136	CD59 molecule (CD59 blood group)	Homo sapiens	54-58
25542415-10	2015	After adjustment, each 10-mL/min/1.73 m(2) decrement in Clcr was associated with 0.01 (95% CI, 0.004-0.017) m/s slower 7-m usual walking speed and 0.008 (95% CI, 0.002-0.014) m/s slower 400-m walking speed.	clcr	56-60	CD59 molecule (CD59 blood group)	Homo sapiens	29-34
25542415-13	2015	During a mean follow-up of 7.1 +- 2.5 years, each 10-mL/min/1.73 m(2) lower baseline Clcr was associated with 0.024 (95% CI, 0.01-0.037) kg/y greater decline in knee strength.	clcr	85-89	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
25585871-5	2015	Under optimized 2.0 V of applied potential, 38 C of temperature, and 500 mL min(-1) of oxygen flow, over 90% of phenol, 60% of TOC and 20% of salinity were removed during 300 min of electrolysis time.	Oxygen	87-93	CD59 molecule (CD59 blood group)	Homo sapiens	76-82
24903851-1	2015	The emergence of an association between gadolinium-based contrast agents (GBCA) and the rare condition nephrogenic systemic fibrosis (NSF) led to a warning in 2006 from the Food and Drug Administration (FDA) restricting the use of the GBCAs to patients with an estimated glomerular filtration rate of &gt;30 mL/min/1.73m(2) .	Gadolinium	40-50	CD59 molecule (CD59 blood group)	Homo sapiens	311-316
24402441-8	2015	Mean VO(2max) was 5.18 +- 0.66 l O2 min-1 corresponding to 57.0 +- 4.1 mL O2 min-1 kg-1.	Oxygen	33-35	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
25923243-10	2015	Serum creatinine fully normalized by twelve weeks after cessation of telaprevir in 83% of patients, however experiencing a significant creatinine rise during telaprevir use was associated with a 6.6mL/min/1.73m2 decrease in estimated glomerular filtration rate at twelve months in an adjusted model.	Creatinine	135-145	CD59 molecule (CD59 blood group)	Homo sapiens	201-206
25923243-10	2015	Serum creatinine fully normalized by twelve weeks after cessation of telaprevir in 83% of patients, however experiencing a significant creatinine rise during telaprevir use was associated with a 6.6mL/min/1.73m2 decrease in estimated glomerular filtration rate at twelve months in an adjusted model.	telaprevir	158-168	CD59 molecule (CD59 blood group)	Homo sapiens	201-206
25918842-6	2015	Carbohydrates oxidation rate decreased significantly with time (from 0.84 +- 0.31 to 0.53 +- 0.24 g   min(-1), respectively; p &lt; 0.001), being estimated well enough by the algorithm (p = NS).	Carbohydrates	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
25600582-7	2015	At room temperature in CO2-buffered water and under continuous H2 as the electron donor, the synthesized material (4.9 wt% Pd) was the most active at a Pd-In ratio of 4, with a first-order rate constant (k(obs) = 0.241 L min(-1) g(cata)(-1)) that was 1.3x higher than that of conventional Pd-In/Al2O3 (5 wt% Pd; 0.19 L min(-1) g(cata)(-1)).	Palladium	123-125	CD59 molecule (CD59 blood group)	Homo sapiens	221-227
25600582-7	2015	At room temperature in CO2-buffered water and under continuous H2 as the electron donor, the synthesized material (4.9 wt% Pd) was the most active at a Pd-In ratio of 4, with a first-order rate constant (k(obs) = 0.241 L min(-1) g(cata)(-1)) that was 1.3x higher than that of conventional Pd-In/Al2O3 (5 wt% Pd; 0.19 L min(-1) g(cata)(-1)).	Palladium	123-125	CD59 molecule (CD59 blood group)	Homo sapiens	319-325
25682031-7	2015	Stroke severity and eGFR were also synergistically related to 6-month mortality, with an adjusted hazard ratio of 21.19 (95% CI, 9.69-46.35) in patients with NIHSS &gt;15 and eGFR &lt;15 mL/min/1.73 m(2), compared with those with NIHSS 0-5 and eGFR 60-119 mL/min/1.73 m(2).	nihss	158-163	CD59 molecule (CD59 blood group)	Homo sapiens	190-195
25682031-7	2015	Stroke severity and eGFR were also synergistically related to 6-month mortality, with an adjusted hazard ratio of 21.19 (95% CI, 9.69-46.35) in patients with NIHSS &gt;15 and eGFR &lt;15 mL/min/1.73 m(2), compared with those with NIHSS 0-5 and eGFR 60-119 mL/min/1.73 m(2).	nihss	158-163	CD59 molecule (CD59 blood group)	Homo sapiens	259-264
25291501-12	2015	Further studies are required in Indigenous patients with creatinine clearance &lt;30 ml min(-1) .	Creatinine	57-67	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
25638441-2	2015	Complexed cadmium ions were eluted from solid phase by 5 mL, nitric acid (2.0 M) with the flow rate of 2 mL min(-1).The resulted solution was used for accumulation of the cadmium metal at the surface of the carbon paste electrode at -1.3 V reduction potential.	Cadmium	10-17	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
25638441-2	2015	Complexed cadmium ions were eluted from solid phase by 5 mL, nitric acid (2.0 M) with the flow rate of 2 mL min(-1).The resulted solution was used for accumulation of the cadmium metal at the surface of the carbon paste electrode at -1.3 V reduction potential.	Cadmium	171-184	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
25585871-5	2015	Under optimized 2.0 V of applied potential, 38 C of temperature, and 500 mL min(-1) of oxygen flow, over 90% of phenol, 60% of TOC and 20% of salinity were removed during 300 min of electrolysis time.	Phenol	112-118	CD59 molecule (CD59 blood group)	Homo sapiens	76-82
25230001-6	2015	RESULTS: Peak oxygen consumption (VO2peak) and heart rate in UBT and TMT were 34.1 +- 4.1 vs 58.3 +- 2.6 mL   min-1   kg-1 and 185 +- 8 vs 197 +- 8 beats/min, respectively, and both variables were of significantly lower magnitude during UBT (P &lt; .001).	Oxygen	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	110-130
25230001-6	2015	RESULTS: Peak oxygen consumption (VO2peak) and heart rate in UBT and TMT were 34.1 +- 4.1 vs 58.3 +- 2.6 mL   min-1   kg-1 and 185 +- 8 vs 197 +- 8 beats/min, respectively, and both variables were of significantly lower magnitude during UBT (P &lt; .001).	N-[(R)-({[(Benzyloxy)carbonyl]amino}methyl)(Hydroxy)phosphoryl]-L-Leucylglycine	61-64	CD59 molecule (CD59 blood group)	Homo sapiens	110-130
26419105-3	2015	By using desflurane under continuous infusion of remifentanil 0.2-0.5 mug x kg(-1) x min(-1), BIS values were maintained between 40 and 60 during the surgery.	Desflurane	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	85-91
26419105-3	2015	By using desflurane under continuous infusion of remifentanil 0.2-0.5 mug x kg(-1) x min(-1), BIS values were maintained between 40 and 60 during the surgery.	Remifentanil	49-61	CD59 molecule (CD59 blood group)	Homo sapiens	85-91
25442109-9	2015	On average, estimated glomerular function improved over the first year on tenofovir [1.10 ml/min/1.73 m(2) average increase over 12 months (95% CI: 0.80; 1.40)].	Tenofovir	74-83	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
26080847-4	2015	Remifentanil infusion rate was 0.2 microg kg-1  min-1, while the propofol infusion rate was adjusted to maintain BIS values within the range of 30-50.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
25641192-8	2015	None of the complexes show antifungal activity except Cu-phen (MIC = 11.71 mugmL(-1) on Candidaalbicans) which was tested for comparison.	cu-phen	54-61	CD59 molecule (CD59 blood group)	Homo sapiens	63-71
25683972-8	2015	Compared with placebo, treatment with FCM was associated with an increase in eGFR [treatment effect: week 4, 2.11 +- 1.21 (P = 0.082); week 12, 2.41 +- 1.33 (P = 0.070); and week 24, 2.98 +- 1.44 mL/min/1.73 m(2) (P = 0.039)].	ferric carboxymaltose	38-41	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
26117894-7	2015	When NH3 flow rate is 20 mL x min(-1), the spectral line intensity of nitrogen active atom reaches a maximum at the same applied voltage peak-peak value.	Nitrogen	70-78	CD59 molecule (CD59 blood group)	Homo sapiens	30-36
26401735-10	2015	Relaxation was continued via the continuous infusion of vecuronium (0.8-1.2 mug kg-1 min-1) to provide a TOF of 2 throughout the surgery.	Vecuronium Bromide	56-66	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
25766030-4	2015	The mutagenic potential at the CD59 locus was more than 2-fold higher (p&lt;0.01) in AL cells exposed to a cytotoxic concentration (1 mumol/L) of MC-LR for 30 days than in untreated control cells, which was consistent with the formation of micronucleus.	Aluminum	85-87	CD59 molecule (CD59 blood group)	Homo sapiens	31-35
25766030-4	2015	The mutagenic potential at the CD59 locus was more than 2-fold higher (p&lt;0.01) in AL cells exposed to a cytotoxic concentration (1 mumol/L) of MC-LR for 30 days than in untreated control cells, which was consistent with the formation of micronucleus.	cyanoginosin LR	146-151	CD59 molecule (CD59 blood group)	Homo sapiens	31-35
25441927-6	2015	Hydrogen generation kinetics followed a Langmuir-type isotherm with reaction rate constant and adsorption constant of 6.77x10(-6) mol min(-1) and 14.45 M(-1), respectively.	Hydrogen	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	134-140
25970926-7	2015	Argon as shielding gas can eliminate CN band generating and reduce spectral background, also plays a role in stabilizing the are, and argon flow 3.5 L x min(-1) was selected.	Argon	134-139	CD59 molecule (CD59 blood group)	Homo sapiens	153-159
25246335-9	2015	In secondary analyses, we observed that a 10 mL/min/1.73 m(2) lower eGFR was associated with a 0.11 mIU/L higher serum TSH (95% CI 0.10-0.11 mIU/L higher serum TSH, P &lt; 0.001).	Thyrotropin	119-122	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
25246335-9	2015	In secondary analyses, we observed that a 10 mL/min/1.73 m(2) lower eGFR was associated with a 0.11 mIU/L higher serum TSH (95% CI 0.10-0.11 mIU/L higher serum TSH, P &lt; 0.001).	Thyrotropin	160-163	CD59 molecule (CD59 blood group)	Homo sapiens	48-53
25051124-8	2015	Peak Wingate HR was significantly higher (189 +- 8 vs 185 +- 9 beats min-1) in CAF-5 vs PL, respectively.	caf-5	79-84	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
25595126-7	2015	Compared with insulin-treated type 2 patients with diabetes, sulfonylurea-treated patients (33%) were older (median age 82 vs 76 years, p=0.007), had worse renal function (median estimated glomerular filtration rate 38 vs 56 mL/min/1.73 m(2), p=0.019) and lower HbA1c (median 6.7% vs 8.4%, p&lt;0.0001).	Sulfonylurea Compounds	61-73	CD59 molecule (CD59 blood group)	Homo sapiens	228-233
25435240-4	2015	Acetonitrile and acetate buffer pH 5.0 at 0.60 mL min(-1) were used as mobile phase to perform the separations before spectrophotometric detection.	Acetates	17-24	CD59 molecule (CD59 blood group)	Homo sapiens	50-56
25423488-5	2015	The retention times of the xenon in the column are 61.2, 42.2 and 23.5 at the flow rate of 1200, 1600 and 2000 mL min(-1), respectively, but the breakthrough times are 51.4, 38.6 and 35.1 min.	Xenon	27-32	CD59 molecule (CD59 blood group)	Homo sapiens	114-120
25590277-2	2015	VLY along with intermedilysin (ILY) from Streptococcus intermedius have been attributed to a group of cholesterol-dependent cytolysins (CDCs) whose pore-forming activity depends on human CD59 (hCD59).	Cholesterol	102-113	CD59 molecule (CD59 blood group)	Homo sapiens	187-191
25590277-2	2015	VLY along with intermedilysin (ILY) from Streptococcus intermedius have been attributed to a group of cholesterol-dependent cytolysins (CDCs) whose pore-forming activity depends on human CD59 (hCD59).	Cholesterol	102-113	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
25590277-6	2015	We further demonstrate that cholesterol binding by VLY is sufficient to trigger the formation of oligomeric complexes on cholesterol rich-liposomes lacking hCD59.	Cholesterol	28-39	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
24743611-8	2015	However, preoperative aspirin use was associated with a significant decrease in postoperative AKI and 30-day mortality in patients with CKD undergoing cardiac surgery, in particular, the survival benefit associated with aspirin was greater in patients with CKD (vs normal kidney function): 30-day mortality was reduced by 23.3%, 58.2%, or 70.0% for patients with baseline eGFR more than or equal to 90, 30 to 59, or 15 to 30 mL/min/1.73 m2, respectively (P trend &lt; 0.001).	Aspirin	22-29	CD59 molecule (CD59 blood group)	Homo sapiens	428-433
24743611-8	2015	However, preoperative aspirin use was associated with a significant decrease in postoperative AKI and 30-day mortality in patients with CKD undergoing cardiac surgery, in particular, the survival benefit associated with aspirin was greater in patients with CKD (vs normal kidney function): 30-day mortality was reduced by 23.3%, 58.2%, or 70.0% for patients with baseline eGFR more than or equal to 90, 30 to 59, or 15 to 30 mL/min/1.73 m2, respectively (P trend &lt; 0.001).	Aspirin	220-227	CD59 molecule (CD59 blood group)	Homo sapiens	428-433
25918454-7	2015	The 45 subjects with increased BDNF following valsartan/hydrochlorothiazide treatment exhibited a significantly reduced eGFR (-8.8 +- 14.9 mL/min/1.73 m(2); P &lt; 0.001).	Valsartan	46-55	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
25918454-7	2015	The 45 subjects with increased BDNF following valsartan/hydrochlorothiazide treatment exhibited a significantly reduced eGFR (-8.8 +- 14.9 mL/min/1.73 m(2); P &lt; 0.001).	Hydrochlorothiazide	56-75	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
27187193-3	2015	CD59 binds to complement components CS and C9 and prevents the polymerization of C9, which is required for the formation of the membrane attack complex (MAC).	Cesium	36-38	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
27187193-5	2015	CD59 is inserted into the membrane by a glycosylphosphatidylinositol (GPI) anchor.	Glycosylphosphatidylinositols	40-68	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
27187193-5	2015	CD59 is inserted into the membrane by a glycosylphosphatidylinositol (GPI) anchor.	Glycosylphosphatidylinositols	70-73	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
24806737-3	2015	Ten elite male cross-country skiers (mean +- SD; 28.2 +- 5.4 y, 181 +- 8 cm, 77.9 +- 9.4 kg, 69.5 +- 4.3 mL   min-1   kg-1 maximal oxygen uptake [VO2max]) performed 2 sessions of roller-skiing on a treadmill: a 2 x 3-km time trial and the same 6-km at an imposed submaximal speed followed by a final 800-m time trial.	Oxygen	131-137	CD59 molecule (CD59 blood group)	Homo sapiens	110-122
25382640-5	2015	Estimated glomerular filtration rate was reduced in patients with high UA levels of both sexes (65+-17 vs 72+-16 mL/min/1.73 m(2) , P&lt;.001, for women; 70+-16 vs 76+-15 mL/min/1.73 m(2) , P&lt;.03, for men).	Uric Acid	71-73	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
25444672-0	2015	Silencing of CD59 enhanced the sensitivity of HT29 cells to 5-Fluorouracil and Oxaliplatin.	Fluorouracil	60-74	CD59 molecule (CD59 blood group)	Homo sapiens	13-17
25444672-0	2015	Silencing of CD59 enhanced the sensitivity of HT29 cells to 5-Fluorouracil and Oxaliplatin.	Oxaliplatin	79-90	CD59 molecule (CD59 blood group)	Homo sapiens	13-17
25444672-1	2015	Complement regulatory proteins (CD55 and CD59) were known to be expressed in many tumors and tumor cell lines including colorectal carcinoma, and were proposed as immunotherapy targets, however whether knocking down of CD55 and CD59 will affect the sensitivity of HT-29 cells to chemotherapy drugs for example, 5-Fluorouracil and Oxaliplatin and their possible mechanisms haven"t been studied.	Fluorouracil	311-325	CD59 molecule (CD59 blood group)	Homo sapiens	41-45
25444672-1	2015	Complement regulatory proteins (CD55 and CD59) were known to be expressed in many tumors and tumor cell lines including colorectal carcinoma, and were proposed as immunotherapy targets, however whether knocking down of CD55 and CD59 will affect the sensitivity of HT-29 cells to chemotherapy drugs for example, 5-Fluorouracil and Oxaliplatin and their possible mechanisms haven"t been studied.	Fluorouracil	311-325	CD59 molecule (CD59 blood group)	Homo sapiens	228-232
25444672-1	2015	Complement regulatory proteins (CD55 and CD59) were known to be expressed in many tumors and tumor cell lines including colorectal carcinoma, and were proposed as immunotherapy targets, however whether knocking down of CD55 and CD59 will affect the sensitivity of HT-29 cells to chemotherapy drugs for example, 5-Fluorouracil and Oxaliplatin and their possible mechanisms haven"t been studied.	Oxaliplatin	330-341	CD59 molecule (CD59 blood group)	Homo sapiens	41-45
25444672-1	2015	Complement regulatory proteins (CD55 and CD59) were known to be expressed in many tumors and tumor cell lines including colorectal carcinoma, and were proposed as immunotherapy targets, however whether knocking down of CD55 and CD59 will affect the sensitivity of HT-29 cells to chemotherapy drugs for example, 5-Fluorouracil and Oxaliplatin and their possible mechanisms haven"t been studied.	Oxaliplatin	330-341	CD59 molecule (CD59 blood group)	Homo sapiens	228-232
25444672-5	2015	We found that silencing CD59 in HT-29 cells could significantly enhance their sensitivity to 5-FU (P &lt; 0.05) and Oxaliplatin (P &lt; 0.05), and significantly reduced their IC50 concentration.	Fluorouracil	93-97	CD59 molecule (CD59 blood group)	Homo sapiens	24-28
25444672-5	2015	We found that silencing CD59 in HT-29 cells could significantly enhance their sensitivity to 5-FU (P &lt; 0.05) and Oxaliplatin (P &lt; 0.05), and significantly reduced their IC50 concentration.	Oxaliplatin	116-127	CD59 molecule (CD59 blood group)	Homo sapiens	24-28
25791185-8	2015	Furthermore, there was an increase in peak oxygen con-sumption (1.7 ml O2 kg-1 min-1; CI95%: 0.1 to 3.3, P &lt; 0.05) and muscular strength (P &lt; 0.001).	Oxygen	43-49	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
25541963-8	2014	Maximal insulin response following arginine challenge was also significantly attenuated (iAUC HME: 7.14 [4.22-10.5] vs. controls 10.2 [7.91-12.70] nmol l-1 min-1 p&lt;0.05), indicative of an impaired beta-cell reserve.	Arginine	35-43	CD59 molecule (CD59 blood group)	Homo sapiens	156-161
25247018-7	2014	RESULTS: Uric acid levels were negatively associated with eGFR (P = 0.002), especially in patients with CKD (eGFR &lt; 60 mL/min/1.73 m(2)) (P &lt; 0.001).	Uric Acid	9-18	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
25501441-6	2014	This same pattern of findings induced by AB was observed during exercise (SV: 71.1 +- 4.1 vs. 65.5 +- 4.1 mL and CO: 6.3 +- 0.4 vs. 5.2 +- 0.4 L min(-1); P &lt;= 0.05); however, Qfv did not reach statistical significance.	ab	41-43	CD59 molecule (CD59 blood group)	Homo sapiens	145-151
24961827-10	2014	The frequencies of retinopathy and GFR &lt; 60 mL/min/1.73 m(2) were higher not only in patients with TSH &gt;= 4.5 mU/l (odds ratio 1.878 and 2.271, respectively) but also in those with TSH levels of 2.5-4.4 mU/l (odds ratio 1.493 and 2.286, respectively), when compared with patients with TSH levels of 0.4-2.5 mU/l.	Thyrotropin	102-105	CD59 molecule (CD59 blood group)	Homo sapiens	50-55
25457436-7	2014	RESULTS: Annual eGFR decline was 25% higher in subjects with elevated versus normal mean homocysteine level (0.90 +- 0.16 ml/min/1.37 m(2) vs. 0.72 +- 0.14 ml/min/1.37 m(2), p&lt;0.001).	Homocysteine	89-101	CD59 molecule (CD59 blood group)	Homo sapiens	125-130
25457436-7	2014	RESULTS: Annual eGFR decline was 25% higher in subjects with elevated versus normal mean homocysteine level (0.90 +- 0.16 ml/min/1.37 m(2) vs. 0.72 +- 0.14 ml/min/1.37 m(2), p&lt;0.001).	Homocysteine	89-101	CD59 molecule (CD59 blood group)	Homo sapiens	159-164
25210977-5	2014	Finally, the polymer-glass microfluidic device was used for the synthesis of a natural product, tryptanthrin, by flash chemistry under high pressure induced conditions (synthetic yield: 90%, flow rate: 10.5 mL min(-1), reaction time: 14 ms).	tryptanthrine	96-108	CD59 molecule (CD59 blood group)	Homo sapiens	210-216
25231186-6	2014	Vildagliptin decreased glycemia (P: 598 +- 8 vs. V: 573 +- 9 mmol l-1 min-1, P &lt; 0.05) during intraduodenal lipid.	Vildagliptin	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
28509189-2	2014	His creatinine clearance levels had fallen to 76.3 mL/min/1.73 m2.	Creatinine	4-14	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
25312351-8	2014	RESULTS: In this trial, levetiracetam total clearance decreased proportionally with creatinine clearance: 52, 31, 25, 20 and 11 mL/min/1.73 m(2) in healthy controls and in patients with mild, moderate, severe renal impairment, and ESRD, respectively.	Levetiracetam	24-37	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
25312351-8	2014	RESULTS: In this trial, levetiracetam total clearance decreased proportionally with creatinine clearance: 52, 31, 25, 20 and 11 mL/min/1.73 m(2) in healthy controls and in patients with mild, moderate, severe renal impairment, and ESRD, respectively.	Creatinine	84-94	CD59 molecule (CD59 blood group)	Homo sapiens	131-136
24713588-6	2014	For PAVM patients, the age-adjusted pulse rise was 0.79 min(-1) greater for every 1% greater drop in oxygen saturation on standing (p&lt;0.001).	Oxygen	101-107	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
25731063-7	2014	Then, diltiazem (0.5 mug x kg(-1) x min(-1)) was continuously administered, and the infusion rate of remifentanil was increased to 0.3 mug x kg(-1) x min(-1).	Diltiazem	6-15	CD59 molecule (CD59 blood group)	Homo sapiens	36-42
25237200-2	2014	The absence of two glycosylphosphatidylinositol (GPI)-anchored proteins, CD55 and CD59, leads to uncontrolled complement activation that accounts for hemolysis and other PNH manifestations.	Glycosylphosphatidylinositols	19-47	CD59 molecule (CD59 blood group)	Homo sapiens	82-86
25237200-2	2014	The absence of two glycosylphosphatidylinositol (GPI)-anchored proteins, CD55 and CD59, leads to uncontrolled complement activation that accounts for hemolysis and other PNH manifestations.	Glycosylphosphatidylinositols	49-52	CD59 molecule (CD59 blood group)	Homo sapiens	82-86
25024132-6	2014	Both Ag/CNT-CHI/graphite immunoelectrodes (using MAGE A2 and MAGE A11) were independently capable of distinguishing specific and nonspecific analytes like CD59, D-dimers, etc.	Graphite	16-24	CD59 molecule (CD59 blood group)	Homo sapiens	155-159
25693341-7	2014	SpO2 decreased to 13% associated with heart rate of 38 beats   min-1 immediately before restoration of ventilation and oxygenation.	spo2	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
25069780-7	2014	Decreasing the FGF from 10 to 5 and 2 L min(-1) with the Aisys caused a rebound in sevoflurane concentration to &gt;= 50 ppm.	Sevoflurane	83-94	CD59 molecule (CD59 blood group)	Homo sapiens	40-46
24960544-3	2014	DESIGN: Oral cholecalciferol (10,000 IU weekly) administered to subjects with 25(OH)D levels &lt; 20 etag/mL and eGFR &gt; 60 mL/min/1.73 m(2) (n = 25), chronic kidney disease (CKD) (n = 27), or end stage renal disease (ESRD) (n = 14).	Cholecalciferol	13-28	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
25161188-1	2014	UNLABELLED: A subgroup of the cholesterol-dependent cytolysin (CDC) family of pore-forming toxins (PFTs) has an unusually narrow host range due to a requirement for binding to human CD59 (hCD59), a glycosylphosphatidylinositol (GPI)-linked complement regulatory molecule.	Cholesterol	30-41	CD59 molecule (CD59 blood group)	Homo sapiens	182-186
25453132-2	2014	These small molecules can accumulate at distances up to several cm from sites of damage and this is likely to involve cell-to-cell jasmonate transport.Also, and independently of jasmonate synthesis, transport and perception, different long distance wound signals that stimulate distal jasmonate synthesis are propagated at apparent speeds of several cm min-1 to tissues distal to wounds in a mechanism that involves clade 3 GLUTAMATE RECEPTOR-LIKE (GLR) genes.	jasmonic acid	131-140	CD59 molecule (CD59 blood group)	Homo sapiens	353-358
25222854-2	2014	For most of that time, the rate of propofol was 120-160 mcg kg-1 min-1 and never exceeded 160 mcg kg-1 min-1.	Propofol	35-43	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
32262202-2	2014	In this work, the surface of an antifouling polymer matrix - a silicone modified with a highly mobile PEO-silane amphiphile - was characterized while undergoing dynamic surface reorganization in aqueous solution via off-resonance tapping mode atomic force microscopy (AFM) and while monitoring surface changes at a rate >25 mum2 min-1.	Polymers	44-51	CD59 molecule (CD59 blood group)	Homo sapiens	329-334
32262202-2	2014	In this work, the surface of an antifouling polymer matrix - a silicone modified with a highly mobile PEO-silane amphiphile - was characterized while undergoing dynamic surface reorganization in aqueous solution via off-resonance tapping mode atomic force microscopy (AFM) and while monitoring surface changes at a rate >25 mum2 min-1.	Silicones	63-71	CD59 molecule (CD59 blood group)	Homo sapiens	329-334
24533667-8	2014	Multivariate analyses found that lithium duration was independently associated with adverse renal outcome in patients with eGFR &lt; 60 mL/min/1.73 m(2).	Lithium	33-40	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
24533667-9	2014	In this sub-population, lithium users had clinically important decreases in eGFR when compared to non-lithium users: 10.3 vs. 0.40 mL/min/1.73 m(2) (p = 0.017).	Lithium	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	134-139
24533667-11	2014	Lithium appears to be an important risk factor for renal dysfunction when eGFR is &lt;60 mL/min/1.73 m(2).	Lithium	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
25233498-11	2014	The area under the ROC curve of NT-proBNP for identifying left ventricular failure in patients with renal failure (eGFR&lt;90 mL/min/1.73 m2) was 0.649 and reached significant difference (95% CI:0.548-0.749, p=0.005).	nt-probnp	32-41	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
24627995-4	2014	The dose of GSNO was increased incrementally to 100 mug min(-1) whilst maintaining blood pressure of &gt;140/80 mmHg.	S-Nitrosoglutathione	12-16	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
24627995-7	2014	RESULTS: Augmentation index fell at 30 mug min(-1) S-nitrosoglutathione (-6%, 95% confidence interval 0.6 to 13%), a dose that did not affect blood pressure.	S-Nitrosoglutathione	51-71	CD59 molecule (CD59 blood group)	Homo sapiens	43-49
25070608-5	2014	This membrane exhibited a promising oxygen permeation value of 4.8 mL min(-1)  cm(-2) at 1000  C upon using Ar and air as the sweep and feed gases, respectively.	Oxygen	36-42	CD59 molecule (CD59 blood group)	Homo sapiens	70-76
25070608-6	2014	Mimicking oxyfuel operating conditions by switching argon to pure CO2 as a sweep gas at 1000  C and air as feed enabled an oxygen flux value of 5.6 mL min(-1)  cm(-2) to be reached.	Argon	52-57	CD59 molecule (CD59 blood group)	Homo sapiens	151-157
25070608-6	2014	Mimicking oxyfuel operating conditions by switching argon to pure CO2 as a sweep gas at 1000  C and air as feed enabled an oxygen flux value of 5.6 mL min(-1)  cm(-2) to be reached.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	66-69	CD59 molecule (CD59 blood group)	Homo sapiens	151-157
25070608-6	2014	Mimicking oxyfuel operating conditions by switching argon to pure CO2 as a sweep gas at 1000  C and air as feed enabled an oxygen flux value of 5.6 mL min(-1)  cm(-2) to be reached.	Oxygen	123-129	CD59 molecule (CD59 blood group)	Homo sapiens	151-157
25070608-7	2014	Finally, under the same conditions and increasing the oxygen partial pressure to 0.1 MPa in the feed, the oxygen permeation reached 12 mL min(-1)  cm(-2).	Oxygen	54-60	CD59 molecule (CD59 blood group)	Homo sapiens	138-144
25070608-7	2014	Finally, under the same conditions and increasing the oxygen partial pressure to 0.1 MPa in the feed, the oxygen permeation reached 12 mL min(-1)  cm(-2).	Oxygen	106-112	CD59 molecule (CD59 blood group)	Homo sapiens	138-144
25070608-9	2014	Finally, the membrane stability over a period of 150 h under CO2-rich sweep gas showed a low degradation rate of 2.4x10(-2)  mL min(-1)  cm(-2) per day.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	61-64	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
24955521-3	2014	This homologue was shown to encode a predicted open reading frame (ORF) of 122 amino acids (aa) orthologous to human CD59 with a 25 aa signal peptide, a mature protein containing 10 cysteines and a conserved CD59/Ly-6 family motif "CCXXXXCN".	Cysteine	182-191	CD59 molecule (CD59 blood group)	Homo sapiens	117-121
24955521-5	2014	Molecular modeling of FhCD59-1.1 with human CD59 confirmed the presence of the three-finger protein domain found in the CD59 family and predicted three disulphide bonds in the F. hepatica sequence.	disulphide	152-162	CD59 molecule (CD59 blood group)	Homo sapiens	24-28
24641488-7	2014	The estimated linear rate of decline in eGFR on tenofovir was -1.1 (95% CI -1.5 to -0.8) mL/min/1.73 m(2) per year and its recovery after discontinuing tenofovir was 2.1 (95% CI 1.3 to 2.9) mL/min/1.73 m(2) per year.	Tenofovir	48-57	CD59 molecule (CD59 blood group)	Homo sapiens	92-97
24641488-7	2014	The estimated linear rate of decline in eGFR on tenofovir was -1.1 (95% CI -1.5 to -0.8) mL/min/1.73 m(2) per year and its recovery after discontinuing tenofovir was 2.1 (95% CI 1.3 to 2.9) mL/min/1.73 m(2) per year.	Tenofovir	48-57	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
25185963-7	2014	RESULTS: Patients treated with CECC had a significantly higher mean logistic EuroSCORE (6.3% vs. 5.0%; p &lt; 0.001), a slightly lower rate of preoperative myocardial infarction (46% vs. 51%; p = 0.01) and a higher rate of impaired renal function (eGFR &lt; 60 mL/min/1.73 m2: 24% vs. 20%; p = 0.01) compared to MECC-patients.	cecc	31-35	CD59 molecule (CD59 blood group)	Homo sapiens	264-269
25161188-1	2014	UNLABELLED: A subgroup of the cholesterol-dependent cytolysin (CDC) family of pore-forming toxins (PFTs) has an unusually narrow host range due to a requirement for binding to human CD59 (hCD59), a glycosylphosphatidylinositol (GPI)-linked complement regulatory molecule.	Cholesterol	30-41	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
25161188-1	2014	UNLABELLED: A subgroup of the cholesterol-dependent cytolysin (CDC) family of pore-forming toxins (PFTs) has an unusually narrow host range due to a requirement for binding to human CD59 (hCD59), a glycosylphosphatidylinositol (GPI)-linked complement regulatory molecule.	Glycosylphosphatidylinositols	198-226	CD59 molecule (CD59 blood group)	Homo sapiens	182-186
25161188-1	2014	UNLABELLED: A subgroup of the cholesterol-dependent cytolysin (CDC) family of pore-forming toxins (PFTs) has an unusually narrow host range due to a requirement for binding to human CD59 (hCD59), a glycosylphosphatidylinositol (GPI)-linked complement regulatory molecule.	Glycosylphosphatidylinositols	198-226	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
25161188-1	2014	UNLABELLED: A subgroup of the cholesterol-dependent cytolysin (CDC) family of pore-forming toxins (PFTs) has an unusually narrow host range due to a requirement for binding to human CD59 (hCD59), a glycosylphosphatidylinositol (GPI)-linked complement regulatory molecule.	Glycosylphosphatidylinositols	228-231	CD59 molecule (CD59 blood group)	Homo sapiens	182-186
25161188-1	2014	UNLABELLED: A subgroup of the cholesterol-dependent cytolysin (CDC) family of pore-forming toxins (PFTs) has an unusually narrow host range due to a requirement for binding to human CD59 (hCD59), a glycosylphosphatidylinositol (GPI)-linked complement regulatory molecule.	Glycosylphosphatidylinositols	228-231	CD59 molecule (CD59 blood group)	Homo sapiens	188-193
25338385-4	2014	The results showed that, adopting the optimal molar ratio of EDTA/CA (1:1), when the pH of the solution was 3, the stirring time was 30 min, the stirring rate was 150 r x min(-1) and the L/S was 5:1, the removal rates of arsenic, cadmium, copper and lead could reach 11.72%, 43.39%, 24.36% and 27.17%, respectively.	Edetic Acid	61-65	CD59 molecule (CD59 blood group)	Homo sapiens	171-177
24880873-10	2014	Using the chip, basal fatty acid and glycerol concentrations ranged from 0.18 to 0.7 nmol x 10(6) cell(-1) min(-1) and from 0.23 to 0.85 nmol x 10(6) cell(-1) min(-1), respectively.	Glycerol	37-45	CD59 molecule (CD59 blood group)	Homo sapiens	107-113
24842984-5	2014	Compared with nonusers, risk of lactic acidosis or elevated lactate concentrations in current metformin users was significantly associated with a renal function &lt;60 mL/min/1.73 m(2) (adjusted HR 6.37 [95% CI 1.48-27.5]).	Lactic Acid	60-67	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
24842984-5	2014	Compared with nonusers, risk of lactic acidosis or elevated lactate concentrations in current metformin users was significantly associated with a renal function &lt;60 mL/min/1.73 m(2) (adjusted HR 6.37 [95% CI 1.48-27.5]).	Metformin	94-103	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
24842984-7	2014	CONCLUSIONS: Our study is consistent with current recommendations that the renal function of metformin users should be adequately monitored and that the dose of metformin should be adjusted, if necessary, if renal function falls below 60 mL/min/1.73 m(2).	Metformin	161-170	CD59 molecule (CD59 blood group)	Homo sapiens	241-246
24743965-8	2014	In pre-capillary pulmonary hypertension, oxygen uptake was also lower at the anaerobic threshold (41 +- 11% versus 50 +- 8% predicted, p=0.04) and at peak exercise (12.8 +- 1.6 versus 15.0 +- 2.5 mL   kg(-1)   min(-1), p=0.02).	Oxygen	41-47	CD59 molecule (CD59 blood group)	Homo sapiens	210-216
24721989-5	2014	RESULTS: The average peak values for all of the drivers with respect to oxygen uptake and heart rate were 4.5+-0.8 L min-1 (56.7+-7.9 mL min-1 kg-1) and 193+-5 beats min-1, respectively.	Oxygen	72-78	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
25199327-6	2014	Catecholamine surge was controlled with 50 microg x kg(-1) x min(-1) continuous infusion of landiolol hydrochloride and IV bolus phentolamine.	Catecholamines	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	61-67
25199327-6	2014	Catecholamine surge was controlled with 50 microg x kg(-1) x min(-1) continuous infusion of landiolol hydrochloride and IV bolus phentolamine.	landiolol	92-115	CD59 molecule (CD59 blood group)	Homo sapiens	61-67
25199329-3	2014	Her Sp(O2) was 92-93% even after administration of 10 l x min(-1) oxygen through a reservoir-attached face mask.	Oxygen	66-72	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
25199332-5	2014	min(-1) landiolol and 1.0 microg x kg(-1) hr(-1) dexmedetomidine.	landiolol	8-17	CD59 molecule (CD59 blood group)	Homo sapiens	0-6
24721989-5	2014	RESULTS: The average peak values for all of the drivers with respect to oxygen uptake and heart rate were 4.5+-0.8 L min-1 (56.7+-7.9 mL min-1 kg-1) and 193+-5 beats min-1, respectively.	Oxygen	72-78	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
24721989-5	2014	RESULTS: The average peak values for all of the drivers with respect to oxygen uptake and heart rate were 4.5+-0.8 L min-1 (56.7+-7.9 mL min-1 kg-1) and 193+-5 beats min-1, respectively.	Oxygen	72-78	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
24736771-7	2014	In trials where subjects arrived euhydrated and hypohydrated, the mean change in HR for every 1% DeltaBML was 3 and 3 b min-1, respectively.	deltabml	97-105	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
25173323-6	2014	Butane (C4H10) gas is used to coat the inner wall of pipes with smooth and homogeneous DLC coatings with thicknesses up to 5 mum in a short time using a deposition rate of 70 +- 10 nm min(-1).	butane	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	184-190
25173323-6	2014	Butane (C4H10) gas is used to coat the inner wall of pipes with smooth and homogeneous DLC coatings with thicknesses up to 5 mum in a short time using a deposition rate of 70 +- 10 nm min(-1).	c4h10	8-13	CD59 molecule (CD59 blood group)	Homo sapiens	184-190
25423832-3	2014	Water was used as mobile phase, the flow rate was 0.7 mL x min(-1), and the temperature was set at 30 C. The evaporated light scattering detector was adopted.	Water	0-5	CD59 molecule (CD59 blood group)	Homo sapiens	59-65
25423832-4	2014	The drift tube temperature was 55 C, and nitrogen was used as carrier gas, with the flow rate of 2.0 L x min(-1) and gain of 1.0.	Nitrogen	41-49	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
24846806-0	2014	Spironolactone use and higher hospital readmission for Medicare beneficiaries with heart failure, left ventricular ejection fraction &lt;45%, and estimated glomerular filtration rate &lt;45 ml/min/1.73 m(2.).	Spironolactone	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
24901940-3	2014	The results of this long-term permeation operation revealed a stepwise increase in oxygen permeation values at 1000  C after each thermal cycle, reaching from 1.38 cm(3) (STP) min(-1) cm(-2) in the first cycle to 1.75 cm(3) (STP) min(-1) cm(-2) in the fourth cycle.	Oxygen	83-89	CD59 molecule (CD59 blood group)	Homo sapiens	176-182
24901940-3	2014	The results of this long-term permeation operation revealed a stepwise increase in oxygen permeation values at 1000  C after each thermal cycle, reaching from 1.38 cm(3) (STP) min(-1) cm(-2) in the first cycle to 1.75 cm(3) (STP) min(-1) cm(-2) in the fourth cycle.	Oxygen	83-89	CD59 molecule (CD59 blood group)	Homo sapiens	230-236
24901940-5	2014	Despite a partial decrease in oxygen permeation fluxes at 850  C, a steady state of 0.25 cm(3) (STP) min(-1) cm(-2) was reached and maintained for more than 100 h. The newly developed PSCF membrane also exhibited a higher oxygen permeation flux with He and CO2 sweeping at all measured temperatures compared to a similar La0.6Sr0.4Co0.8Fe0.2O3-delta (LSCF) membrane.	Oxygen	222-228	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
24901940-5	2014	Despite a partial decrease in oxygen permeation fluxes at 850  C, a steady state of 0.25 cm(3) (STP) min(-1) cm(-2) was reached and maintained for more than 100 h. The newly developed PSCF membrane also exhibited a higher oxygen permeation flux with He and CO2 sweeping at all measured temperatures compared to a similar La0.6Sr0.4Co0.8Fe0.2O3-delta (LSCF) membrane.	Helium	250-252	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
24901940-5	2014	Despite a partial decrease in oxygen permeation fluxes at 850  C, a steady state of 0.25 cm(3) (STP) min(-1) cm(-2) was reached and maintained for more than 100 h. The newly developed PSCF membrane also exhibited a higher oxygen permeation flux with He and CO2 sweeping at all measured temperatures compared to a similar La0.6Sr0.4Co0.8Fe0.2O3-delta (LSCF) membrane.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	257-260	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
24251918-9	2014	There was significant benefit on creatinine clearance in patients with impaired renal function at 6 months [+12.23 (+5.26, +18.82) ml min(-1) , P = 0.0003] and at 12 months 4.63 [-4.55, 13.82] P = 0.32 I(2)  = 75%.	Creatinine	33-43	CD59 molecule (CD59 blood group)	Homo sapiens	134-140
24659381-4	2014	The target analyte (trace copper) was quantitatively retained at pH = 4 and eluted with 6.0 mL of 0.5 M HNO3 at flow rates of 40 and 10 mL min-1 for analyte passage and elution steps, respectively, through the disks modified with 17.0 mg of EDTD.	Copper	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
24924474-1	2014	The objective was to investigate the expression and prognostic value of CD59 expression in patients with diffuse large B-cell lymphoma (DLBCL) who underwent rituximab-cyclophosphamide, adriamycin, vincristine, and prednisone (R-CHOP).	rituximab-cyclophosphamide	157-183	CD59 molecule (CD59 blood group)	Homo sapiens	72-76
24924474-1	2014	The objective was to investigate the expression and prognostic value of CD59 expression in patients with diffuse large B-cell lymphoma (DLBCL) who underwent rituximab-cyclophosphamide, adriamycin, vincristine, and prednisone (R-CHOP).	Doxorubicin	185-195	CD59 molecule (CD59 blood group)	Homo sapiens	72-76
24924474-1	2014	The objective was to investigate the expression and prognostic value of CD59 expression in patients with diffuse large B-cell lymphoma (DLBCL) who underwent rituximab-cyclophosphamide, adriamycin, vincristine, and prednisone (R-CHOP).	Vincristine	197-208	CD59 molecule (CD59 blood group)	Homo sapiens	72-76
24924474-1	2014	The objective was to investigate the expression and prognostic value of CD59 expression in patients with diffuse large B-cell lymphoma (DLBCL) who underwent rituximab-cyclophosphamide, adriamycin, vincristine, and prednisone (R-CHOP).	Prednisone	214-224	CD59 molecule (CD59 blood group)	Homo sapiens	72-76
25177848-16	2014	Average 24 hours creatinine clearance was 98.64 +- 22 mL/min/1.73 m2, with chronic renal failure data in 6 patients.	Creatinine	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
24939508-4	2014	We show that on addition of micromolar concentrations of hyaluronic acid, the resulting fluid viscoelasticity can be used to control the focal position of particles at Reynolds numbers up to Re 10,000 with corresponding flow rates and particle velocities up to 50 ml min(-1) and 130 m s(-1).	Hyaluronic Acid	57-72	CD59 molecule (CD59 blood group)	Homo sapiens	267-273
25375112-5	2014	RESULTS: Data suggests high intensity aerobic interval training increases peak oxygen consumption by a standardized mean difference of 3.60 mL/kg-1/min-1 (95% confidence interval, 0.28-4.91).	Oxygen	79-85	CD59 molecule (CD59 blood group)	Homo sapiens	143-153
25158503-3	2014	The RSM analysis results demonstrated that the effect of individual operation parameter on phosphorus removal was followed as the order of Al/P &gt; pH &gt; MS, and the optimal process parameters with phosphorus removal efficiency of 97.8% were Al/P = 2.49, pH = 8.3 and MS 398 r x min(-1), respectively.	Phosphorus	91-101	CD59 molecule (CD59 blood group)	Homo sapiens	282-288
24002363-3	2014	RESULTS: The para-hydrogen to ortho-hydrogen velocity constant, k, near room temperature (292 K) was determined to be 8.27 +- 1.30 L/mol   min(-1).	Hydrogen	18-26	CD59 molecule (CD59 blood group)	Homo sapiens	139-145
24002363-3	2014	RESULTS: The para-hydrogen to ortho-hydrogen velocity constant, k, near room temperature (292 K) was determined to be 8.27 +- 1.30 L/mol   min(-1).	Hydrogen	36-44	CD59 molecule (CD59 blood group)	Homo sapiens	139-145
24692739-6	2014	Eight patients received docetaxel (35 mg/m(2), day 1) and carboplatin-based (area under the curve, 4 mg min(-1) mL(-1); day 1) chemotherapy with an oral itraconazole solution (400 mg, days -2 to 2), repeated every two weeks.	Carboplatin	58-69	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
24726385-7	2014	CD59 expression is reduced by glucose and in rodent diabetes models but upregulated in human diabetic islets, potentially reflecting compensatory reactions.	Glucose	30-37	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
24321330-3	2014	Increase in O &amp; G mass loading from 5 to 20 mg min(-1) caused decreases in both dissolved oxygen concentration and sediment redox potential, which affected treatment performance.	o &amp	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	51-57
24321330-3	2014	Increase in O &amp; G mass loading from 5 to 20 mg min(-1) caused decreases in both dissolved oxygen concentration and sediment redox potential, which affected treatment performance.	Oxygen	94-100	CD59 molecule (CD59 blood group)	Homo sapiens	51-57
24662458-7	2014	Patients treated with cisplatin were younger (median age 61 versus 63, p &lt; 0.01) and had less comorbidities (summary comorbidity score &gt; 2, 7.7% versus 12.8%, p = 0.01) and higher eGFR (87 versus 84 mL/min/1.73 m).	Cisplatin	22-31	CD59 molecule (CD59 blood group)	Homo sapiens	208-213
24783622-12	2014	CONCLUSIONS: Remifentanil infusion at 0.02 microg x kg(-1) x min(-1) can safely be used without any serious adverse events, while it may not be enough for postoperative analgesia.	Remifentanil	13-25	CD59 molecule (CD59 blood group)	Homo sapiens	61-67
24594813-11	2014	The carryover in the interface was eliminated by flushing the desorption chamber with acetonitrile at 1mL min(-1) for 2min.	acetonitrile	86-98	CD59 molecule (CD59 blood group)	Homo sapiens	106-112
25895337-7	2014	And the highest catalytic rate 4.29 microM x min-1 was obtained when the volume ratio of PBs: methanol was 5 : 5.	Lead	89-92	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
24917692-7	2014	The retention numbers were significantly reduced at higher speeds (by 50% at 15 and 73% at 20 m   min(-1), respectively) in the nigari-treated group when compared to those of the control group, respectively.	nigari	128-134	CD59 molecule (CD59 blood group)	Homo sapiens	98-104
23913929-4	2014	Baseline CKD(cys) was defined as eGFR(cys) less than 60 mL/min/1.73 m(2).	Cysteine	13-16	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
24724447-8	2014	Regular chest compression and intravenous administration of dopamine (5 microg x kg(-1) x min(-1)) resulted in successful recovery of sinus rhythm.	Dopamine	60-68	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
24468357-4	2014	The reduction of water content in the carrier gas to 2.2-2.4 g m(-3) and to 1.8-2.0 g m(-3) for the short and long desolvation unit, respectively, was achieved at an electrospray flow rate of 1000 nL min(-1).	Water	17-22	CD59 molecule (CD59 blood group)	Homo sapiens	200-206
25895337-7	2014	And the highest catalytic rate 4.29 microM x min-1 was obtained when the volume ratio of PBs: methanol was 5 : 5.	Methanol	94-102	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
24499533-8	2014	Patients received vasoactive support with (mean +- standard deviation, SD) 0.57 +- 0.49 mug   kg-1   min-1 norepinephrine resulting in a mean arterial pressure of 103 +- 13 mmHg and a systemic vascular resistance of 943 +- 248 dyn   s   cm-5.	Norepinephrine	107-121	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
24356515-8	2014	DNP increased during exercise (11.1 +- 3.5 rest, 18.8 +- 2.3 exercise, 13.2 +- 2.2 recovery, ml min(-1) g(-1), P &lt; 0.0001), and the increase was largest in nondependent lung (110 +- 61% increase in nondependent, 63 +- 35% in mid, 70 +- 33% in dependent, P &lt; 0.005).	2,4-Dinitrophenol	0-3	CD59 molecule (CD59 blood group)	Homo sapiens	96-102
24370425-4	2014	Compared with NiCo nanochains, the Pt-loaded NiCo nanochains present exceedingly high catalytic activity toward the hydrolytic dehydrogenation of ammonia borane aqueous under ambient atmosphere at room temperature, where the Ni16Co80/Pt4 nanochains exhibit high catalytic activity with a lower activation energy of 45.72 kJ mol(-1) and a superior dehydrogenation rate of 1.17 x 10(4) mL min(-1) g(-1), suggesting the potential application in hydrogen fuel and chemical industry.	Platinum	35-37	CD59 molecule (CD59 blood group)	Homo sapiens	387-393
24370425-4	2014	Compared with NiCo nanochains, the Pt-loaded NiCo nanochains present exceedingly high catalytic activity toward the hydrolytic dehydrogenation of ammonia borane aqueous under ambient atmosphere at room temperature, where the Ni16Co80/Pt4 nanochains exhibit high catalytic activity with a lower activation energy of 45.72 kJ mol(-1) and a superior dehydrogenation rate of 1.17 x 10(4) mL min(-1) g(-1), suggesting the potential application in hydrogen fuel and chemical industry.	Niacin	45-49	CD59 molecule (CD59 blood group)	Homo sapiens	387-393
24370425-4	2014	Compared with NiCo nanochains, the Pt-loaded NiCo nanochains present exceedingly high catalytic activity toward the hydrolytic dehydrogenation of ammonia borane aqueous under ambient atmosphere at room temperature, where the Ni16Co80/Pt4 nanochains exhibit high catalytic activity with a lower activation energy of 45.72 kJ mol(-1) and a superior dehydrogenation rate of 1.17 x 10(4) mL min(-1) g(-1), suggesting the potential application in hydrogen fuel and chemical industry.	Ammonia borane	146-160	CD59 molecule (CD59 blood group)	Homo sapiens	387-393
24198163-0	2014	Oxygen at a high flow rate (35 L min -1) via face mask for preoxygenation.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	33-39
24163425-13	2014	In response to fentanyl during exercise, HF patients had a reduction in ventilation (63 +- 6 versus 44 +- 3 l min(-1), P &lt; 0.05) due to a lower respiratory rate (30 +- 1 versus 26 +- 2 breaths min(-1), P &lt; 0.05).	Fentanyl	15-23	CD59 molecule (CD59 blood group)	Homo sapiens	110-116
24485011-2	2014	RESULTS: Optimum chromatographic separations among pheniramine maleate, naphazoline hydrochloride and stress-induced degradation products have been achieved within 10 minutes by using an Agilent zorbax eclipse XDB C18 column (150 mm x 4.6 mm, 5 mum) as the stationary phase with a mobile phase consisted of 10 mM phosphate buffer pH 2.8 containing 0.5% triethlamine and methanol (68:32, v/v) at a flow rate of 1 mL min-1.	Silicon Dioxide	195-201	CD59 molecule (CD59 blood group)	Homo sapiens	415-420
24321183-7	2014	In patients with raised baseline plasma IL-6/8/10 and/or PTX3 the eGFR decline during the trial was significantly less in those treated with atorvastatin compared to placebo (mean change, -3.36; vs. + 1.25 mL/min/1.73 m2/year; difference, 4.61 95% CI 0.98 - 8.25; p = 0.002), whilst those without raised inflammatory biomarkers showed no difference.	Atorvastatin	141-153	CD59 molecule (CD59 blood group)	Homo sapiens	209-214
24163425-13	2014	In response to fentanyl during exercise, HF patients had a reduction in ventilation (63 +- 6 versus 44 +- 3 l min(-1), P &lt; 0.05) due to a lower respiratory rate (30 +- 1 versus 26 +- 2 breaths min(-1), P &lt; 0.05).	Fentanyl	15-23	CD59 molecule (CD59 blood group)	Homo sapiens	196-202
24454946-1	2014	The glycosylphosphatidylinositol (GPI)-anchored molecule CD59 has been implicated in the modulation of T cell responses, but the underlying molecular mechanism of CD59 influencing T cell signaling remained unclear.	Glycosylphosphatidylinositols	4-32	CD59 molecule (CD59 blood group)	Homo sapiens	57-61
24601117-4	2014	Spinal anesthesia was performed with bupivacaine 12.5 mg. At the beginning of anesthesia SPO2 was 97% in supine position, but it rapidly decreased to less than 90% and 3 l x min(-1) oxygen was supplied with a facial mask.	Oxygen	182-188	CD59 molecule (CD59 blood group)	Homo sapiens	174-180
24300978-9	2014	Rate of infusion of &lt;25 mg m(-2) min(-1) and the presence of homozygous major allele for SLC28A3 (CC genotype) were each associated with an almost two-fold increase in the formation clearance of dFdCTP.	dfdctp	198-204	CD59 molecule (CD59 blood group)	Homo sapiens	36-42
24300978-11	2014	Infusion rate &lt;25 mg m(-2) min(-1) and carriers for SLC28A3 variant were each associated with about two-fold higher dFdCTP formation clearance.	dfdctp	119-125	CD59 molecule (CD59 blood group)	Homo sapiens	30-36
24454946-1	2014	The glycosylphosphatidylinositol (GPI)-anchored molecule CD59 has been implicated in the modulation of T cell responses, but the underlying molecular mechanism of CD59 influencing T cell signaling remained unclear.	Glycosylphosphatidylinositols	34-37	CD59 molecule (CD59 blood group)	Homo sapiens	57-61
24454946-1	2014	The glycosylphosphatidylinositol (GPI)-anchored molecule CD59 has been implicated in the modulation of T cell responses, but the underlying molecular mechanism of CD59 influencing T cell signaling remained unclear.	Glycosylphosphatidylinositols	34-37	CD59 molecule (CD59 blood group)	Homo sapiens	163-167
24741693-5	2014	In comparison, this also exceeds the overall manufacturing speed of the polymer solar cell foil with a width of 305 mm which is currently 1 m min-1 for complete encapsulated and tested foil.	Polymers	72-79	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
24224759-9	2014	At month 12, across the entire population of patients with DSA cause-unk, the outcomes were favorable: the measured glomerular filtration rate was 63.8 +- 16.4 mL/min/1.73 m(2), the screening biopsies showed low frequencies of microvascular inflammation and no transplant glomerulopathy, and graft and patient survival were 100%.	dsa	59-62	CD59 molecule (CD59 blood group)	Homo sapiens	163-168
24809060-7	2014	Results show that there was an increment in cardiac output response due to metaboreflex activity at T1 as compared to T0 (545.4 +- 683.9 mL   min(-1) versus 220.5 +- 745.4 mL   min(-1), P &lt; 0.05).	metaboreflex	75-87	CD59 molecule (CD59 blood group)	Homo sapiens	142-148
24809060-7	2014	Results show that there was an increment in cardiac output response due to metaboreflex activity at T1 as compared to T0 (545.4 +- 683.9 mL   min(-1) versus 220.5 +- 745.4 mL   min(-1), P &lt; 0.05).	metaboreflex	75-87	CD59 molecule (CD59 blood group)	Homo sapiens	177-183
24296610-1	2014	OBJECTIVE: Recently, we reported that low-dose landiolol (1.5 microg kg(-1) min(-1)), an ultra-short-acting beta-blocker, safely decreased the heart rate (HR) in patients with acute decompensated heart failure (ADHF) and sinus tachycardia, thereby improving cardiac function.	landiolol	47-56	CD59 molecule (CD59 blood group)	Homo sapiens	76-82
24296610-3	2014	METHODS: We enrolled 23 ADHF patients with rapid AF (HR &gt;=120 beats min(-1) and New York Heart Association class III-IV) and systolic heart failure (SHF: n = 12) or diastolic heart failure (DHF: n = 11) who received conventional therapy with diuretics, vasodilators, and/or low-dose inotropes.	adhf	24-28	CD59 molecule (CD59 blood group)	Homo sapiens	71-77
24296610-4	2014	They were administered continuous intravenous infusion of low-dose landiolol (1.0-2.0 microg kg(-1) min(-1)), and their electrocardiograms and blood pressures were monitored for 24 h thereafter.	landiolol	67-76	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
24600876-2	2014	The influence of the parameters such as initial pH (5-7), initial concentration of Fe2+ (1-2.5mM) and rate of H202 addition (1.87-3.74mmol min-1) was investigated.	h202	110-114	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
24749309-2	2014	The mean pulmonary oxygen consumption was higher than the same value calculated by the reverse Fick principle--148.4 +/- 39.9 ml x min(-1) x m(-2) and 120 +/- 35.1 ml x min(-1) x m(-2), respectively, the mean difference between two methods was 28.4 +/- 18.4 ml x min(-1) x m(-2).	Oxygen	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	131-137
24749309-2	2014	The mean pulmonary oxygen consumption was higher than the same value calculated by the reverse Fick principle--148.4 +/- 39.9 ml x min(-1) x m(-2) and 120 +/- 35.1 ml x min(-1) x m(-2), respectively, the mean difference between two methods was 28.4 +/- 18.4 ml x min(-1) x m(-2).	Oxygen	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	169-175
24749309-2	2014	The mean pulmonary oxygen consumption was higher than the same value calculated by the reverse Fick principle--148.4 +/- 39.9 ml x min(-1) x m(-2) and 120 +/- 35.1 ml x min(-1) x m(-2), respectively, the mean difference between two methods was 28.4 +/- 18.4 ml x min(-1) x m(-2).	Oxygen	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	169-175
24301419-2	2014	The results show that the calibration coefficient for a flow rate of 0.3 L min(-1) was 1.27 in Fukushima waters for germanium semiconductor scintillations related to (133)Cs concentrations and radioactive caesium amounts.	Cesium	171-173	CD59 molecule (CD59 blood group)	Homo sapiens	75-81
24301419-2	2014	The results show that the calibration coefficient for a flow rate of 0.3 L min(-1) was 1.27 in Fukushima waters for germanium semiconductor scintillations related to (133)Cs concentrations and radioactive caesium amounts.	Cesium	205-212	CD59 molecule (CD59 blood group)	Homo sapiens	75-81
24067879-6	2014	Increased eGFR with telbivudine treatment was also observed in patients at increased risk for renal impairment: patients with baseline eGFRs of 60-89 mL/min/1.73 m(2) (+17.2%), older than 50 years (+11.4%), and with liver fibrosis/cirrhosis (+7.2% for patients with Ishak fibrosis score at 5-6).	Telbivudine	20-31	CD59 molecule (CD59 blood group)	Homo sapiens	153-158
25487930-3	2014	In remifentanil group remifentanil was infused intravenously with micro pump in 0.05-0.1 microg kg-1 min-1.	Remifentanil	3-15	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
25487930-3	2014	In remifentanil group remifentanil was infused intravenously with micro pump in 0.05-0.1 microg kg-1 min-1.	Remifentanil	22-34	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
24778878-7	2014	Gadolinium-enhanced MRI was performed on 312 of 837 patients, including 23 with severe renal failure (GFR &lt; 30 mL/min/1.73 cm(2)) and 289 with GFR &gt; 30.	Gadolinium	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
26229219-6	2014	The instrument is operated using 6.0 mL min-1 helium as the collision cell gas and in kinetic energy discrimination mode, interferences are successfully removed for the analysis of 52Cr (40Ar12C and 35Cl16O1H) and 60Ni (44Ca16O).	Helium	46-52	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
24084219-8	2014	When SQ treprostinil was converted to IV treprostinil, the initial mean (range) dose decreased from 84.9 (36.5-167) to 70.8 (24-114) ng kg-1 min-1.	treprostinil	41-53	CD59 molecule (CD59 blood group)	Homo sapiens	141-146
24084219-9	2014	When SQ treprostinil was converted to IV epoprostenol, the dose decreased from 24.5 (17.5-30) to 13.3 (9-20) ng kg-1 min-1.	treprostinil	8-20	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
24084219-9	2014	When SQ treprostinil was converted to IV epoprostenol, the dose decreased from 24.5 (17.5-30) to 13.3 (9-20) ng kg-1 min-1.	Epoprostenol	41-53	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
25484617-4	2014	The polymer concentration (5-50 wt%) and flow rates of the feeds (50-300 microl min-1) were important parameters in controlling the nanosphere diameter.	Polymers	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
24701731-11	2014	FdDES at FGF 0.5 L x min(-1) (6.13 +/- 0.12) was significantly higher than FdDES at 1 and 2 L x min(-1) (5.68 +/- 0.08, 5.54 +/- 0.07, respectively), but not significantly different between FGF 1 and 2 L x min(-1).	fddes	0-5	CD59 molecule (CD59 blood group)	Homo sapiens	21-27
24701731-14	2014	The calculated liquid desflurane consumption per hour at FGF rate of 0.5, 1 and 2 L x min(-1) were 8.77 +/- 0.17, 16.28 +/- 0.24 and 31.73 +/- 0.41 mL x hr(-1).	Desflurane	22-32	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
24404861-4	2014	High-intensity interval training had a beneficial effect on maximal O2 uptake (mean change, +-90% confidence intervals: 0.19 L   min(-1), +-0.19, respectively), on the O2 uptake at the gas exchange threshold (0.09 L   min(-1), +-0.13) and on the O2 cost of sub-maximal exercise (-0.04 L   min(-1), +-0.04).	Oxygen	68-70	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
24404861-5	2014	A beneficial effect on the contribution of lipid (0.06 g   min(-1), +-0.06) and carbohydrate (-0.23 g   min(-1), +-0.14) oxidation was observed during sub-maximal exercise, but not for the maximal rate of fat oxidation (0.04 g   min(-1), +-0.08).	Carbohydrates	80-92	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
24404861-5	2014	A beneficial effect on the contribution of lipid (0.06 g   min(-1), +-0.06) and carbohydrate (-0.23 g   min(-1), +-0.14) oxidation was observed during sub-maximal exercise, but not for the maximal rate of fat oxidation (0.04 g   min(-1), +-0.08).	Carbohydrates	80-92	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
25531940-6	2014	CONCLUSIONS: Proteinuria decreased significantly after add-on spironolactone treatment in patients with 1&lt;=UACR&lt;3.5 g/g Cr, UACR &gt;=3.5 g/g Cr, and eGFR &gt;=60 mL/min/1.73 m2, and in the non-escape group.	Spironolactone	62-76	CD59 molecule (CD59 blood group)	Homo sapiens	172-177
24142755-9	2014	AR ratio was highest in patient group 4 (eGFR &lt; 30 mL/min/1.73 m2) and/or on chronic haemodialysis therapy, whereas there was little difference among the other three groups.	Argon	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
24558938-2	2014	On admission, Glasgow Coma Scale score was 7; arterial blood pressure was 113/73 mm Hg; heart rate was 157 beats x min(-1), and percutaneous oxygen saturation was 99% on 10 l x min(-1) of oxygen.	Oxygen	188-194	CD59 molecule (CD59 blood group)	Homo sapiens	177-183
24618238-7	2014	In patients with DM2 and a creatinine clearance &lt; 60 ml/min/1.73 m2 certain anti-diabetic drugs are contraindicated, while others should be dose-adjusted.	Creatinine	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
25401320-2	2014	PyC showed significant reactivity, and the pseudo-first-order kinetic rate constant for decomposition of H(2)O(2) and degradation of Acid Red B (ARB) were 3.4 and 14.89 (10-3 min-1) respectively when pH = 5.	h(2)	105-109	CD59 molecule (CD59 blood group)	Homo sapiens	175-180
25401320-2	2014	PyC showed significant reactivity, and the pseudo-first-order kinetic rate constant for decomposition of H(2)O(2) and degradation of Acid Red B (ARB) were 3.4 and 14.89 (10-3 min-1) respectively when pH = 5.	acid red B	133-143	CD59 molecule (CD59 blood group)	Homo sapiens	175-180
25401320-2	2014	PyC showed significant reactivity, and the pseudo-first-order kinetic rate constant for decomposition of H(2)O(2) and degradation of Acid Red B (ARB) were 3.4 and 14.89 (10-3 min-1) respectively when pH = 5.	acid red B	145-148	CD59 molecule (CD59 blood group)	Homo sapiens	175-180
24195625-5	2013	Mean total CHO oxidation (CHOTOT) rates were 2.35 +- 0.18, 2.76 +- 0.08, and 2.61 +- 0.17 g   min(-1) with MD, MD+F, and MD+F+P, respectively, although not significantly different.	CAV protocol	11-14	CD59 molecule (CD59 blood group)	Homo sapiens	94-100
24344940-11	2013	Mean uric acid levels of patients with intact graft function (estimated glomerular filtration rate &gt;= 60 mL/min/1.73 m2) was lower than the patients with a low estimated glomerular filtration rate (291 +- 67 mumol/L and 353 +- 71 mumol/L; P = .000).	Uric Acid	5-14	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
24640900-5	2013	The changes of air flow rate from 300 to 900 mL x min(-1) and temperature from 20 degrees C to 40 degrees C resulted in increases of the benzene diffusion flux.	Benzene	137-144	CD59 molecule (CD59 blood group)	Homo sapiens	50-56
23670361-1	2013	The increase in oxygen uptake &gt; 100 ml   min-1 during steady state exercise when elevating the inspired fractional air content (FinO2) from 0.21-1.00 defines the "spirografic oxygen deficit" (SOD).	Oxygen	16-22	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
24094167-7	2013	Optimal results were obtained with 5 wt.% PCL in DMAC solution sprayed within the stable cone-jet mode operating window at a flow rate of 15 mul min(-1) for 300 s at 11.1 kV with a working distance of 60mm.	polycaprolactone	42-45	CD59 molecule (CD59 blood group)	Homo sapiens	145-151
24123643-7	2013	Chromatographic separation of the sugars was achieved using a low strength 0.25 mM NaOH solution as mobile phase at a flow rate of 250 muL min-1 at 10  C.	Sugars	34-40	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
24199617-5	2013	A normalized rate of hydrate formation of 64.48 (+-3.82) mol x min(-1) x m(-3) was obtained at 6.0 MPa and 274.2 K. Based on a morphological study, the mechanism of hydrate formation from water dispersed in interstitial pore space of the porous medium is presented.	Water	188-193	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
24020639-4	2013	Rate enhancements up to 113 and 48% were observed, yielding a maximum oxygen flux of 0.32 and 4.53 mL min(-1) cm(-2) under air/helium and air/CO gradients at 950  C, respectively.	Oxygen	70-76	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
23305245-8	2013	Trimethoprim was associated with a decrease in creatinine clearance from 133 to 106 ml min(-1) (P &lt; 0.01) and an increase in plasma lactate from 0.94 to 1.2 mmol l(-1) (P = 0.016).	Trimethoprim	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
23744741-5	2013	As expected, the swelling rate, Ks , decreased when increasing the crosslink density from 78.6 to 14.7 min-1 over a range of 1-20 mol% PEGDA indicating that diffusivity into the matrix is dependent on crosslink density.	Potassium	32-34	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
23744741-5	2013	As expected, the swelling rate, Ks , decreased when increasing the crosslink density from 78.6 to 14.7 min-1 over a range of 1-20 mol% PEGDA indicating that diffusivity into the matrix is dependent on crosslink density.	poly(ethylene glycol)diacrylate	135-140	CD59 molecule (CD59 blood group)	Homo sapiens	103-108
24555402-4	2013	The results showed that the best 31P-NMR spectrum could be obtained with freeze-ried, ground and sieved sediments, 1M HCl as pre-extractant for 16 h, NaOH + 0.05 mol x L(-1) EDTA as main extractant for 16 h, extraction ratio of 1 : 8, and low temperature and high-speed centrifugation (4 degrees C, 10 000 r x min(-1) for 30 min) for avoiding hydrolysis of certain components.	ET bromodomain inhibitor	33-36	CD59 molecule (CD59 blood group)	Homo sapiens	310-316
24555402-4	2013	The results showed that the best 31P-NMR spectrum could be obtained with freeze-ried, ground and sieved sediments, 1M HCl as pre-extractant for 16 h, NaOH + 0.05 mol x L(-1) EDTA as main extractant for 16 h, extraction ratio of 1 : 8, and low temperature and high-speed centrifugation (4 degrees C, 10 000 r x min(-1) for 30 min) for avoiding hydrolysis of certain components.	Hydrochloric Acid	118-121	CD59 molecule (CD59 blood group)	Homo sapiens	310-316
24552059-5	2013	The degradation kinetics of pyridine follows first-order kinetics and k = 5.53 x 10(-3) min-1.	pyridine	28-36	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
24364280-6	2013	After placement of transcutaneous cardiac pacing pads on the chest, we administered isoproterenol at 0.01 microg x kg(-1) x min(-1).	Isoproterenol	84-97	CD59 molecule (CD59 blood group)	Homo sapiens	124-130
24364280-7	2013	We confirmed an increase in HR to 50 beats x min(-1) and induced anesthesia, after which isoproterenol was administered at 0.015 microg x kg(-1) x min(-1).	Isoproterenol	89-102	CD59 molecule (CD59 blood group)	Homo sapiens	147-153
23846824-7	2013	Currently, for prolonged exercise lasting 2-3 h, athletes are advised to ingest carbohydrates at a rate of 60 g h-1 (~1.0-1.1 g min-1) to allow for maximal exogenous glucose oxidation rates.	Carbohydrates	80-93	CD59 molecule (CD59 blood group)	Homo sapiens	128-133
23846824-8	2013	However, well-trained endurance athletes competing longer than 2.5 h can metabolize carbohydrate up to 90 g h-1 (~1.5-1.8 g min-1) provided that multiple transportable carbohydrates are ingested (e.g. 1.2 g min-1 glucose plus 0.6 g min-1 of fructose).	Carbohydrates	84-96	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
24020639-4	2013	Rate enhancements up to 113 and 48% were observed, yielding a maximum oxygen flux of 0.32 and 4.53 mL min(-1) cm(-2) under air/helium and air/CO gradients at 950  C, respectively.	Helium	127-133	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
23763855-3	2013	The consequences of abnormal phosphate homeostasis are evident at estimated glomerular filtration rates &lt;70 mL/min/1.73 m(2), long before serum phosphate levels increase.	Phosphates	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
23902163-4	2013	When tested with a 50-ml reservoir, a high fractional oxygen concentration was achieved: mean (SD) 0.83 (0.11) at a flow of 15 l.min(-1) oxygen.	Oxygen	54-60	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
23902163-4	2013	When tested with a 50-ml reservoir, a high fractional oxygen concentration was achieved: mean (SD) 0.83 (0.11) at a flow of 15 l.min(-1) oxygen.	Oxygen	137-143	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
24744487-6	2013	Maximum oxygen uptake increased from 60.0 +- 1.5 ml min(-1) kg(-1) at the beginning of the season to 65.2 +- 1.4 ml min(-1) kg(-1) (P &lt; 0.05) in the season.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	52-58
24744487-6	2013	Maximum oxygen uptake increased from 60.0 +- 1.5 ml min(-1) kg(-1) at the beginning of the season to 65.2 +- 1.4 ml min(-1) kg(-1) (P &lt; 0.05) in the season.	Oxygen	8-14	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
23694781-4	2013	Overexpression of PIGV, which encodes GPI mannosyltransferase II, restored the surface expression of CD59 and normalized the accumulation of GPI intermediates in the mutant cells.	Glycosylphosphatidylinositols	38-41	CD59 molecule (CD59 blood group)	Homo sapiens	101-105
23954921-3	2013	The sensitivity and response time of the oxygen sensor were evaluated in vitro with a gas pressure chamber system, where oxygen partial pressure was rapidly changed between 5 and 15 kPa, and then in vivo in five healthy adult participants who synchronized their breathing to a metronome set at 10, 20, 30, 40, 50, and 60 breaths min(-1).	Oxygen	41-47	CD59 molecule (CD59 blood group)	Homo sapiens	329-335
24364329-5	2013	The concentration of sulfa antibiotics in the leachate was close to 500 microg.L-1 when the leaching velocity was 2 mL.min-1, while the concentration of sulfa antibiotics in the leachate was between 100-200 microg.L-1 when the leaching velocity was 1 and 1.5 mL.min-1.	dimethyl trisulfide	21-26	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
24364329-5	2013	The concentration of sulfa antibiotics in the leachate was close to 500 microg.L-1 when the leaching velocity was 2 mL.min-1, while the concentration of sulfa antibiotics in the leachate was between 100-200 microg.L-1 when the leaching velocity was 1 and 1.5 mL.min-1.	dimethyl trisulfide	21-26	CD59 molecule (CD59 blood group)	Homo sapiens	262-267
23800880-6	2013	Metabolic rate of glucose increased similarly (~30%) in the two exercise groups in femoral skeletal muscle (MOD 24[9, 39] mumol kg-1 min-1, P = 0.004; HIGH 22[9, 35] mumol kg-1 min-1, P = 0.003) (mean[95% CI]) and in five individual femoral muscle groups but not in femoral SAT.	Glucose	18-25	CD59 molecule (CD59 blood group)	Homo sapiens	133-138
23820621-8	2013	SI(exercise) was significantly higher than SI(rest) (21.6 +- 3.7 vs. 12.5 +- 2.0 10-4 dl kg-1 min-1 per muU/ml, P &lt; 0.0005).	Silicon	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
23780977-6	2013	CONCLUSION: A hydrogen bond (ILY Arg432-hCD59 Glu76) was observed between ILY and hCD59, and a stronger interaction was formed by flexible adjustment between them.	Hydrogen	14-22	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
23296954-5	2013	As expected NaAc ingestion decreased resting fat oxidation (mean +- SD; 0.09 +- 0.02 vs. 0.07 +- 0.02 g min-1 pre- and post-ingestion respectively, p &lt; .05) with no effect upon carbohydrate utilization.	naac	12-16	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
23702615-7	2013	Among them, the microfluidic oxygenator with porous PDMS membrane has the highest gas exchange rate of 1.46 muL min(-1) cm(2) for oxygen and 5.27 muL min(-1) cm(2) for carbon dioxide and performs better than a commercial hollow fiber-based oxygenator by 367 and 233%, respectively.	Oxygen	29-35	CD59 molecule (CD59 blood group)	Homo sapiens	112-118
23702615-7	2013	Among them, the microfluidic oxygenator with porous PDMS membrane has the highest gas exchange rate of 1.46 muL min(-1) cm(2) for oxygen and 5.27 muL min(-1) cm(2) for carbon dioxide and performs better than a commercial hollow fiber-based oxygenator by 367 and 233%, respectively.	Oxygen	29-35	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
23702615-7	2013	Among them, the microfluidic oxygenator with porous PDMS membrane has the highest gas exchange rate of 1.46 muL min(-1) cm(2) for oxygen and 5.27 muL min(-1) cm(2) for carbon dioxide and performs better than a commercial hollow fiber-based oxygenator by 367 and 233%, respectively.	Carbon Dioxide	168-182	CD59 molecule (CD59 blood group)	Homo sapiens	150-156
23623574-8	2013	In participants with and without vitamin D deficiency, annual age-standardized incidences were 0.92% (95% CI, 0.56%-1.30%) and 0.59% (95% CI, 0.51%-0.68%), respectively, for eGFR &lt;60 mL/min/1.72 m2 and 1.50% (95% CI, 1.06%-1.95%) and 0.66% (95% CI, 0.56%-0.76%), respectively, for albuminuria.	Vitamin D	33-42	CD59 molecule (CD59 blood group)	Homo sapiens	189-194
23780977-6	2013	CONCLUSION: A hydrogen bond (ILY Arg432-hCD59 Glu76) was observed between ILY and hCD59, and a stronger interaction was formed by flexible adjustment between them.	Hydrogen	14-22	CD59 molecule (CD59 blood group)	Homo sapiens	82-87
23780368-13	2013	However, with glucose infusion, the heart rate decreased 11 beats min-1, the peak work rate increased 12.5%, and exercise was considered easier by the patient.	Glucose	14-21	CD59 molecule (CD59 blood group)	Homo sapiens	66-71
23666972-9	2013	In contrast, beta-cell glucose sensitivity (19 [12] pmol   min-1   m-2   mM-1 vs 96 [73] of controls, P &lt; .0001) rose (P = .02) only to 31 [26] at 1 year and was lower in nonremitters (16 [18]) than remitters (46 [33]).	Glucose	23-30	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
23731441-5	2013	The release of a model drug, indomethacin, is established by measuring the optical thickness change with time under four different flow rates (i.e. 0, 10, 30, and 50 muL min(-1)).	Indomethacin	29-41	CD59 molecule (CD59 blood group)	Homo sapiens	170-176
23809189-7	2013	RESULTS: Additional oxygen uptake increased over the frequency range to a maximum of 564 (SD 114) ml min-1 at 12 Hz, and the respiratory exchange ratio was close to unity from 4 to 12 Hz.	Oxygen	20-26	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
23597294-7	2013	At a similar supersaturation ratio of ~1.2, ritonavir and celecoxib had slower normalized crystal growth rates (0.20 and 0.91 mg min(-1) m(-2), respectively), while the normalized crystal growth rate of efavirenz was significantly higher (2.97 mg min(-1) m(-2)), resulting in lower levels of crystal growth inhibition by the polymers for efavirenz.	Ritonavir	44-53	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
23597294-7	2013	At a similar supersaturation ratio of ~1.2, ritonavir and celecoxib had slower normalized crystal growth rates (0.20 and 0.91 mg min(-1) m(-2), respectively), while the normalized crystal growth rate of efavirenz was significantly higher (2.97 mg min(-1) m(-2)), resulting in lower levels of crystal growth inhibition by the polymers for efavirenz.	Ritonavir	44-53	CD59 molecule (CD59 blood group)	Homo sapiens	247-253
23597294-7	2013	At a similar supersaturation ratio of ~1.2, ritonavir and celecoxib had slower normalized crystal growth rates (0.20 and 0.91 mg min(-1) m(-2), respectively), while the normalized crystal growth rate of efavirenz was significantly higher (2.97 mg min(-1) m(-2)), resulting in lower levels of crystal growth inhibition by the polymers for efavirenz.	Celecoxib	58-67	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
23597294-7	2013	At a similar supersaturation ratio of ~1.2, ritonavir and celecoxib had slower normalized crystal growth rates (0.20 and 0.91 mg min(-1) m(-2), respectively), while the normalized crystal growth rate of efavirenz was significantly higher (2.97 mg min(-1) m(-2)), resulting in lower levels of crystal growth inhibition by the polymers for efavirenz.	Celecoxib	58-67	CD59 molecule (CD59 blood group)	Homo sapiens	247-253
23846144-2	2013	Levofloxacin undergoes first-order kinetics in the initial stages of the reaction and the apparent first-order rate constants are of the order of 0.167 to 1.807x10-3 min-1.	Levofloxacin	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	166-171
23438722-6	2013	RESULTS: Oxygen uptake was lower during room temp than during cold recovery (0.40 +- 0.05 L x min-1 vs. 0.80 +- 0.12 L x min-1; p&lt;0.01).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
23438722-6	2013	RESULTS: Oxygen uptake was lower during room temp than during cold recovery (0.40 +- 0.05 L x min-1 vs. 0.80 +- 0.12 L x min-1; p&lt;0.01).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
23746236-1	2013	OBJECTIVE: To investigate the distributions of GPI-anchored protein CD59 and C-terminal Src kinase-binding protein (Cbp) in cell membrane of T lymphocytes and the roles in cell activation and proliferation.	Glycosylphosphatidylinositols	47-50	CD59 molecule (CD59 blood group)	Homo sapiens	68-72
23665225-2	2013	Intermedilysin (ILY) is an archetypal member of a cholesterol-dependent cytolysin subclass that hijacks the complement receptor CD59 to make cytotoxic pores in human cells.	Cholesterol	50-61	CD59 molecule (CD59 blood group)	Homo sapiens	128-132
23377698-6	2013	Meta-regression analyses showed that HbA1c and fasting plasma glucose predicted the outcomes iAUC and iAUC min-1, respectively.	Glucose	62-69	CD59 molecule (CD59 blood group)	Homo sapiens	107-112
23577724-8	2013	A GFR &lt;60 mL/min/1.73 m(2) was identified in 56% with Iohexol clearance compared to 8% using the four-variable modified diet in renal disease formula (P &lt; 0.0001).	Iohexol	57-64	CD59 molecule (CD59 blood group)	Homo sapiens	16-21
23577724-13	2013	Iohexol clearance and cystatin C formulae identify a greater proportion of patients with a GFR &lt;60 mL/min/1.73 m(2), which also predicts the development of AKI.	Iohexol	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
23905311-5	2013	Results show that the spectral line intensity from oxygen atom increases with increasing the peak value of the applied voltage, increases with increasing the gas flow rate, reaches its maximum with a gas flow rate of 30 L x min(-1) and then decreases with further increasing the gas flow rate.	Oxygen	51-57	CD59 molecule (CD59 blood group)	Homo sapiens	224-230
23772533-7	2013	Milrinone and olprinone were administered at the rates of 0.5 and 0.3 microg x kg-1 x min-1 at the end of surgery, respectively.	Milrinone	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
23772533-7	2013	Milrinone and olprinone were administered at the rates of 0.5 and 0.3 microg x kg-1 x min-1 at the end of surgery, respectively.	olprinone	14-23	CD59 molecule (CD59 blood group)	Homo sapiens	86-91
23756005-7	2013	Peak oxygen consumption ranged from 21.8 +- 3.8 to 40.0 +- 3.4 mL kg(-1) min(-1) during cutting activities and a search and rescue task, respectively, representing values similar to or higher than the current entry standards.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	73-79
23726595-12	2013	Patients with DeltaUPCR &gt;=20 mg/mmol had worse graft function at 3 months after the biopsy with mean (+-SD) estimated glomerular-filtration rate (eGFR) of 35 +- 19 versus 47 +- 14 mL/min/1.73 m(2) (P = .002), as well as a higher rate of composite graft loss and patient death (37% vs 10%; P = .004).	deltaupcr	14-23	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
23947128-4	2013	The flow rate was 1.0 mL x min(-1), the detection wavelength was 283 nm, and the column temperature was 25 degrees C. RESULT: Under the conditions, gallic acid and hesperidin reached the baseline resolved peak, with a good linearity within the range of 21.6-216.0 mg x L(-1) (r = 0.999 93) for gallic acid, and 4.5-45.0 mg x L(-1) (r = 0.999 95) for hesperidin, respectively.	Gallic Acid	148-159	CD59 molecule (CD59 blood group)	Homo sapiens	27-33
23947128-4	2013	The flow rate was 1.0 mL x min(-1), the detection wavelength was 283 nm, and the column temperature was 25 degrees C. RESULT: Under the conditions, gallic acid and hesperidin reached the baseline resolved peak, with a good linearity within the range of 21.6-216.0 mg x L(-1) (r = 0.999 93) for gallic acid, and 4.5-45.0 mg x L(-1) (r = 0.999 95) for hesperidin, respectively.	Hesperidin	164-174	CD59 molecule (CD59 blood group)	Homo sapiens	27-33
23527765-7	2013	For the particular case of cis-beta-methylstyrene, the catalyst is capable of carrying out 1320 turnovers with a turnover frequency of 11.0 cycles min(-1), generating cis-beta-methylstyrene oxide stereospecifically.	cis-Propenylbenzene	27-49	CD59 molecule (CD59 blood group)	Homo sapiens	147-153
23527765-7	2013	For the particular case of cis-beta-methylstyrene, the catalyst is capable of carrying out 1320 turnovers with a turnover frequency of 11.0 cycles min(-1), generating cis-beta-methylstyrene oxide stereospecifically.	cis-beta-Methylstyrene oxide	167-195	CD59 molecule (CD59 blood group)	Homo sapiens	147-153
23386119-6	2013	The quasi-steady-state currents resulting from chronoamperometric analysis of microdroplets containing 1.0 mM Ru(NH3)6(3+) have relative standard deviations of just 1.8% and 2.8% at flow rates of 30 nL min(-1) and 60 nL min(-1), respectively.	ru(nh3)6	110-118	CD59 molecule (CD59 blood group)	Homo sapiens	202-208
23545994-6	2013	A significant decrease in oxygen consumption (VO2) was observed after surgery, from 1,719 +- 571 to 1609 +- 428 mL min-1, p = 0.036.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
23545994-6	2013	A significant decrease in oxygen consumption (VO2) was observed after surgery, from 1,719 +- 571 to 1609 +- 428 mL min-1, p = 0.036.	vo2	46-49	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
23265287-5	2013	Multivariable logistic regression showed that age (OR = 1.051, P &lt; .001), serum creatinine concentration at start of RRT (OR = 1.004, P &lt; .001) and administration of iodine-containing contrast fluid (OR = 0.830, P = .045) were associated with an eGFR &lt;=60 mL min(-1) 1.73 m(-2).	Iodine	172-178	CD59 molecule (CD59 blood group)	Homo sapiens	268-274
23713218-5	2013	RESULTS: Peak oxygen uptake during exercise using RAD and C2 averaged 3.11 +/- 0.49 and 3.18 +/- 0.50 L x min(-1), respectively.	Oxygen	14-20	CD59 molecule (CD59 blood group)	Homo sapiens	106-112
23555151-4	2013	A quantitative determination of tebipenem was carried out by using a PDA detector at 298 nm, with a flow rate of 1.2 mL min-1.	tebipenem	32-41	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
23584321-6	2013	The best regression model to calculate the O2 consumption (VO2) was: VO2 (L min-1) =-1.264+0.026 bw (kg)+0.195 VD (m).	Oxygen	43-45	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
21559746-8	2013	The FBF response to ACh is lower in hypertensives with HR &lt;=60 min(-1) than in those with HR &gt;=80 min(-1) (10.6 +- 4.2 vs. 13.6 +- 5.1 ml x 100 ml(-1) of tissue x min(-1), P &lt; 0.001).	Acetylcholine	20-23	CD59 molecule (CD59 blood group)	Homo sapiens	66-72
23697200-3	2013	Anesthesia was induced with midazolam (5 mg) and remifentanil (0.1.ag x kg-1 x min-1) and the trachea was intubated following administration of rocuronium.	Remifentanil	49-61	CD59 molecule (CD59 blood group)	Homo sapiens	79-84
23313266-5	2013	The association of low HDL cholesterol with reduced kidney function was also greater in the older age groups: 4.9 (95% CI, 3.5, 6.3), 7.1 (95% CI, 6.0, 8.3), 8.9 (95% CI, 5.4, 11.9) mL/min/1.73 m(2) (P for interaction &lt; .001).	Cholesterol	27-38	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
25016744-3	2013	It is found that more manifested positive changes in indexes of intracardialy hemodynamics in patients with liver cirhhosis usage of valsartan (group III), namely: increased the left ventricular ejection fraction from (58.1 +/- 3.6) % to (65.1 +/- 1.1) % (P &lt; 0.05), the beat index--from (28.99 +/- 2.20) ml/m2 to (36.1 +/- 3.5) ml/m2 (P &lt; 0.05), the heart index to (3.26 +/- 0.70) l/(min2 x m2) from (2.59 +/- 0.80) l/(min2 x m2).	Valsartan	133-142	CD59 molecule (CD59 blood group)	Homo sapiens	391-395
25016744-3	2013	It is found that more manifested positive changes in indexes of intracardialy hemodynamics in patients with liver cirhhosis usage of valsartan (group III), namely: increased the left ventricular ejection fraction from (58.1 +/- 3.6) % to (65.1 +/- 1.1) % (P &lt; 0.05), the beat index--from (28.99 +/- 2.20) ml/m2 to (36.1 +/- 3.5) ml/m2 (P &lt; 0.05), the heart index to (3.26 +/- 0.70) l/(min2 x m2) from (2.59 +/- 0.80) l/(min2 x m2).	Valsartan	133-142	CD59 molecule (CD59 blood group)	Homo sapiens	426-430
23755710-2	2013	Metformin, the first choice oral glucose-lowering agent, is classically contraindicated in case of chronic kidney disease of stages 3-5 (creatinine clearance &lt; 60 ml/min/1.73 m2), because of a risk of accumulation of the biguanide that may lead to lactic acidosis.	Metformin	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
23255310-9	2013	After 3 years of treatment, GFR measured by (99m)Tc-DTPA decreased significantly from 167 +- 46 mL/min/1.73 m2 to 145 +- 27 mL/min/1.73 m2 (P = 0.016).	Technetium Tc 99m Pentetate	49-56	CD59 molecule (CD59 blood group)	Homo sapiens	99-104
23329178-7	2013	Externalization of phosphatidyl serine and nuclear condensation occurred 30 min-2 h after the initiation of cell blebbing.	Phosphatidylserines	19-38	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
23279103-9	2013	Because only 5% of patients had a creatinine clearance between 30 and 50 mL min(-1), further data are needed in such patients.	Creatinine	34-44	CD59 molecule (CD59 blood group)	Homo sapiens	76-82
23059865-6	2013	In STG, V O2max increased (P &lt; 0.01) from 32.6 +- 4.9 to 35.4 +- 6.6 mL min-1 kg-1 and relative V O2 during cycling at 100 W was lowered (P &lt; 0.05) from 55% +- 7% to 50% +- 8% V O2max over 6 months, with no changes in DAG.	Oxygen	10-12	CD59 molecule (CD59 blood group)	Homo sapiens	75-85
23059865-6	2013	In STG, V O2max increased (P &lt; 0.01) from 32.6 +- 4.9 to 35.4 +- 6.6 mL min-1 kg-1 and relative V O2 during cycling at 100 W was lowered (P &lt; 0.05) from 55% +- 7% to 50% +- 8% V O2max over 6 months, with no changes in DAG.	o2max	10-15	CD59 molecule (CD59 blood group)	Homo sapiens	75-85
23241726-0	2013	Intraoperative infusion of 0.6-0.9 microg kg(-1) min(-1) remifentanil induces acute tolerance in young children after laparoscopic ureteroneocystostomy.	Remifentanil	57-69	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
22580790-4	2013	The uranium complex was removed from the resin by 0.1 mol dm(-3) HCl at flow rate of 3.2 mL min(-1) and was mixed with arsenazo III solution (0.05 % solution in 0.1 mol dm(-3) HCl, 3.2 mL min(-1)) and driven to flow through cell of spectrophotometer where its absorbance was measured at 651 nm.	Uranium	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
22580790-4	2013	The uranium complex was removed from the resin by 0.1 mol dm(-3) HCl at flow rate of 3.2 mL min(-1) and was mixed with arsenazo III solution (0.05 % solution in 0.1 mol dm(-3) HCl, 3.2 mL min(-1)) and driven to flow through cell of spectrophotometer where its absorbance was measured at 651 nm.	Uranium	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	188-194
23314690-6	2013	Hypermethylation with low oxygen tension was independently confirmed by bisulfite-pyrosequencing in a subset of functionally relevant genes including CD59, CFB, GRAM3 and ZNF217.	Oxygen	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	150-154
23314690-6	2013	Hypermethylation with low oxygen tension was independently confirmed by bisulfite-pyrosequencing in a subset of functionally relevant genes including CD59, CFB, GRAM3 and ZNF217.	hydrogen sulfite	72-81	CD59 molecule (CD59 blood group)	Homo sapiens	150-154
23849497-7	2013	Across whole-body sweat rates from 0.72 to 3.65 mg.cm-2.min-1, sodium losses of 26.5-49.7 mmol.L-1 could be expected, with the corresponding chloride loss being 26.8-36.7 mmol.L-1.	Sodium	63-69	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
23849497-7	2013	Across whole-body sweat rates from 0.72 to 3.65 mg.cm-2.min-1, sodium losses of 26.5-49.7 mmol.L-1 could be expected, with the corresponding chloride loss being 26.8-36.7 mmol.L-1.	Chlorides	141-149	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
23154992-6	2013	Although the concentration eliciting 50% of the maximal sweating response did not differ between sexes for either agonist (P &gt; 0.1), maximum values were lower in females in response to ACh (0.34 +- 0.12 vs. 0.59 +- 0.19 mg min(-1) cm(-2), P = 0.04) and MCh (0.48 +- 0.12 vs. 0.78 +- 0.26 mg min(-1) cm(-2), P = 0.05).	Acetylcholine	188-191	CD59 molecule (CD59 blood group)	Homo sapiens	226-232
23154992-6	2013	Although the concentration eliciting 50% of the maximal sweating response did not differ between sexes for either agonist (P &gt; 0.1), maximum values were lower in females in response to ACh (0.34 +- 0.12 vs. 0.59 +- 0.19 mg min(-1) cm(-2), P = 0.04) and MCh (0.48 +- 0.12 vs. 0.78 +- 0.26 mg min(-1) cm(-2), P = 0.05).	Acetylcholine	188-191	CD59 molecule (CD59 blood group)	Homo sapiens	294-300
22635246-4	2013	CKD was defined as a persistent decrease in the Cr-based estimated glomerular filtration rate to below 60 mL/min/1.73 m2.	Creatinine	48-50	CD59 molecule (CD59 blood group)	Homo sapiens	109-114
23261285-2	2013	The main advantage of the developed detector is its capability to introduce full column effluent up to 2000 mL min(-1) CO(2) gas directly into the IMS cell relative to 40 mL min(-1) CO(2) gas as a maximum tolerance, reported for the previous IMS detectors.	co(2)	119-124	CD59 molecule (CD59 blood group)	Homo sapiens	111-117
23261285-2	2013	The main advantage of the developed detector is its capability to introduce full column effluent up to 2000 mL min(-1) CO(2) gas directly into the IMS cell relative to 40 mL min(-1) CO(2) gas as a maximum tolerance, reported for the previous IMS detectors.	co(2)	182-187	CD59 molecule (CD59 blood group)	Homo sapiens	174-180
23450442-8	2013	RESULTS: Patients treated with 90Y-DOTATATE had a mean creatinine level of 0.77 +- 0.19 mg/dL and a mean GFR (mL/min/1.73 m2) of 103.6 +- 30.8.	90Y-octreotate, DOTA(0)-Tyr(3)-Thr(8)-	31-43	CD59 molecule (CD59 blood group)	Homo sapiens	113-118
24055914-8	2013	Serum creatinine decreased from 1200 to 170mumol/L 57 with eGFR improving from 4 to 38mL/min/1.73m(2) at four weeks post-transplant.	Creatinine	6-16	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
22762797-5	2013	Despite cessation of exenatide, there was continued deterioration in estimated glomerular filtration rate to 16 ml min(-1) 1.73 m(-2).	Exenatide	21-30	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
23995570-17	2013	CONCLUSION: Steroid pulse therapy in combination with mizoribine following tonsillectomy is effective in improving urinary findings and preserving renal function in the treatment of IgA nephropathy, which remained active in patients with renal impairment (estimated glomerular filtration rate &gt;=20 and &lt;60 mL/min/1.73 m(2)).	Steroids	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	315-320
24135101-6	2013	Solution pH below 3.0 and stirring speed of 700 rev min(-1) could ensure a sufficiently high oxidation rate for Na(2)SO(3) with ferric ion higher than 0.469 mM.	Ferric enterobactin ion	128-134	CD59 molecule (CD59 blood group)	Homo sapiens	52-58
24135101-6	2013	Solution pH below 3.0 and stirring speed of 700 rev min(-1) could ensure a sufficiently high oxidation rate for Na(2)SO(3) with ferric ion higher than 0.469 mM.	sodium sulfide	112-117	CD59 molecule (CD59 blood group)	Homo sapiens	52-58
23108344-5	2012	Furthermore, a designed concept test shows that the as-prepared membranes could load 1.5 kg water or oil at the same time maintained an extremely high air permeability of 2 L min(-1), suggesting their use as promising materials for a variety of potential applications in protective clothing, bioseparation, water purification, tissue engineering, microfluidic systems, etc., and also provided new insight into the design and development of functional hybrid membranes based on FPU.	Water	92-97	CD59 molecule (CD59 blood group)	Homo sapiens	175-181
22770927-12	2012	After adjustment including diabetes, eGFR(cys) categories of &lt;30 and 30-44 mL/min/1.73 m(2) were associated with a 2.8- (95% CI, 1.3-6.3) and 2.1 (95% CI, 1.0-4.7)-fold greater prevalence of frailty compared with GFR(cys) &gt;=60 mL/min/1.73 m(2).	Cysteine	42-45	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
22770927-12	2012	After adjustment including diabetes, eGFR(cys) categories of &lt;30 and 30-44 mL/min/1.73 m(2) were associated with a 2.8- (95% CI, 1.3-6.3) and 2.1 (95% CI, 1.0-4.7)-fold greater prevalence of frailty compared with GFR(cys) &gt;=60 mL/min/1.73 m(2).	Cysteine	42-45	CD59 molecule (CD59 blood group)	Homo sapiens	236-241
22770927-12	2012	After adjustment including diabetes, eGFR(cys) categories of &lt;30 and 30-44 mL/min/1.73 m(2) were associated with a 2.8- (95% CI, 1.3-6.3) and 2.1 (95% CI, 1.0-4.7)-fold greater prevalence of frailty compared with GFR(cys) &gt;=60 mL/min/1.73 m(2).	Cysteine	220-223	CD59 molecule (CD59 blood group)	Homo sapiens	81-86
23247535-10	2012	In addition the administration of continuous oxygen airflow of 2 l min-1 through the suction channel of the flexible bronchoscope was tested as an alternative method to prevent lens fogging.	Oxygen	45-51	CD59 molecule (CD59 blood group)	Homo sapiens	67-72
23010500-10	2012	Moreover, during adrenaline infusion the leptin release from leg skeletal muscle was strongly suppressed (20.5 +- 7.9 ng min(-1), p&lt;0.017), whereas the release from fat was unaltered.	Epinephrine	17-27	CD59 molecule (CD59 blood group)	Homo sapiens	121-127
23010500-11	2012	During saline infusion the adipose tissue release averaged 0.8 +- 0.3 ng min(-1) 100g tissue(-1) whereas skeletal muscle release was 0.5 +- 0.1 ng min(-1) 100g tissue(-1).	Sodium Chloride	7-13	CD59 molecule (CD59 blood group)	Homo sapiens	73-79
23437675-9	2012	The UV/TiO2 reactor was found to be the cheapest option achieving a very good COD removal (82% at 20 min retention time and 10 L min(-1) aeration rate).	titanium dioxide	7-11	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
23379163-12	2012	As the rotational speed was in the range of 10 to 80 r x min(-1), the removal efficiency of nitrobenzene was around 75%.	nitrobenzene	92-104	CD59 molecule (CD59 blood group)	Homo sapiens	57-63
22235139-6	2012	Nonrenal and renal clearances of brivaracetam decreased from 47 and 4.5 to 41 and 1.7 mL/min/1.73 m(2).	brivaracetam	33-45	CD59 molecule (CD59 blood group)	Homo sapiens	89-94
22821302-2	2012	In this study, a novel cancer-targeting short peptide which was composed of 22 amino acids (ACHWPWCHGWHSACDLPMHPMC, abbreviated as sp22) and specifically bound to human CD59 was screened from a M13 phage display library so as to counteract tumor immune escape activity.	achwpwchgwhsacdlpmhpmc	92-114	CD59 molecule (CD59 blood group)	Homo sapiens	169-173
22207257-4	2012	However, the physiological responses after the swimming RST (heart rate 168 +- 7 b min(-1) and blood lactate concentration 5.5 +- 2.0 mmol L(-1)) were lower than typical responses after running or cycling RSTs.	UNII-Y5T2AJP16N	56-59	CD59 molecule (CD59 blood group)	Homo sapiens	83-89
24150080-5	2012	Intra-class correlation coefficient (ICC) scores for power output (W kg(-1)) and oxygen uptake (ml kg(-1) min(-1)) were highly reliable (R1 = 0.96 and 0.96, respectively) and the ICC for RPE was moderately reliable (R1 = 0.83).	Oxygen	81-87	CD59 molecule (CD59 blood group)	Homo sapiens	106-112
24150080-7	2012	A Pearson"s product-moment correlation demonstrated a strong relationship between power output (W kg(-1)) and oxygen uptake (ml kg(-1) min(-1)) for both trials (r = 0.93 and 0.89, respectively).	Oxygen	110-116	CD59 molecule (CD59 blood group)	Homo sapiens	135-141
23007801-9	2012	The mean (SD) corresponding oxygen uptake values for the sedentary, dance, and boxing video games were 6.1 (1.3), 12.8 (3.3), and 17.7 (5.1) mL   min-1   kg-1, respectively.	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	146-158
24977134-11	2013	The magnitude of GFR improvement after N-acetylcysteine administration was less pronounced in the group treated with high-flux biocompatible membranes: +0.17 +- 0.56 mL/min/1.73 m(2) in treatment group and +0.65 +- 0.53 mL/min/1.73 m(2) in control group (P &lt; 0.05).	Acetylcysteine	39-55	CD59 molecule (CD59 blood group)	Homo sapiens	169-174
24977134-11	2013	The magnitude of GFR improvement after N-acetylcysteine administration was less pronounced in the group treated with high-flux biocompatible membranes: +0.17 +- 0.56 mL/min/1.73 m(2) in treatment group and +0.65 +- 0.53 mL/min/1.73 m(2) in control group (P &lt; 0.05).	Acetylcysteine	39-55	CD59 molecule (CD59 blood group)	Homo sapiens	223-228
23236936-4	2012	The patient developed hypotension (from 90/50 to 49/27 mmHg in 20 min) together with tachycardia (111 beats x min(-1)) and desaturation (83%) subsequent to intravenous infusion of Saviosol (dextran 40).	Dextrans	180-188	CD59 molecule (CD59 blood group)	Homo sapiens	110-116
22961267-6	2012	With phentolamine, peak DeltaFVC was enhanced in older adults at each contraction intensity (100 +- 14, 147 +- 22, and 200 +- 26 ml min(-1) 100 mmHg(-1), respectively, P &lt; 0.01 vs. control) but not in younger adults (94 +- 13, 153 +- 13, and 224 +- 27 ml min(-1) 100 mmHg(-1), respectively, P = 0.30-0.81 vs. control).	Phentolamine	5-17	CD59 molecule (CD59 blood group)	Homo sapiens	132-138
22961267-6	2012	With phentolamine, peak DeltaFVC was enhanced in older adults at each contraction intensity (100 +- 14, 147 +- 22, and 200 +- 26 ml min(-1) 100 mmHg(-1), respectively, P &lt; 0.01 vs. control) but not in younger adults (94 +- 13, 153 +- 13, and 224 +- 27 ml min(-1) 100 mmHg(-1), respectively, P = 0.30-0.81 vs. control).	Phentolamine	5-17	CD59 molecule (CD59 blood group)	Homo sapiens	258-264
22855276-9	2012	Baseline urine NO(x) and cGMP were highest in DM-H. l-NMMA led to a decline in GFR in DM-H (152 +- 16 to 140 +- 11 ml min(-1) 1.73 m(-2)) but not DM-N or healthy control participants.	omega-N-Methylarginine	52-58	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
22855276-10	2012	The decline in effective renal plasma flow in response to l-NMMA (806 +- 112 to 539 +- 80 ml min(-1) 1.73 m(-2)) in DM-H was also exaggerated compared with the other groups (repeated measures ANOVA, P &lt; 0.05), along with declines in urinary NO(x) metabolites and cGMP.	omega-N-Methylarginine	58-64	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
23234003-2	2012	Results showed that ozone could be thoroughly decomposed (removal rate was maintaining 100% all along the process studied) for 5 h under the condition of O3 12.89 mg x min(-1), 18 mm diameter glass tube was stuffed by activated carbon (made from coal, 2.0-2.5 mm diameter).	Carbon	228-234	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
22703030-3	2012	The O2 uptake reported by the Moxus system was 83 +- 78 mL min-1 higher (mean +- SD;  3%, +62 micromol s-1, P &lt; 0.001) than that reported by the Douglas-bag method; the bias varied by  2% between the subjects.	Oxygen	4-6	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
22807108-3	2012	A second styrene molecule then binds CYP2E1 with higher affinity (K(ss) = 110 muM) and significantly improves oxidation to achieve a k(cat) of 6.3 nmol   min(-1)   nmol CYP2E1(-1).	Styrene	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	154-160
22807108-9	2012	The inhibitor was a negative allosteric effector on styrene oxidation, because k(cat) decreased 6-fold to 0.98 nmol   min(-1)   nmol CYP2E1(-1).	Styrene	52-59	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
22879534-8	2012	In hyperinflators, heliox reduced end-expiratory chest wall volume and diaphragmatic activity, and increased arterial oxygen content (by 17.8 +- 2.5 ml/l), whereas, in non-hyperinflators, heliox reduced peak-expiratory gastric pressure and increased systemic vascular conductance (by 11.0 +- 2.8 ml min(-1) mmHg(-1)).	heliox	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	299-305
22950636-5	2012	Acrylamide formation and browning index in cookies were considered as the first-order reaction kinetics and the reaction rate constants, k, were in the range of 0.023 to 0.077 (min(-1) ) and 0.019 to 0.063 (min(-1) ), respectively.	Acrylamide	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	177-184
22950636-5	2012	Acrylamide formation and browning index in cookies were considered as the first-order reaction kinetics and the reaction rate constants, k, were in the range of 0.023 to 0.077 (min(-1) ) and 0.019 to 0.063 (min(-1) ), respectively.	Acrylamide	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	207-214
22935584-9	2012	Patients with creatinine clearance (CrCl) 50-80 ml min(-1) on OxCap(+- cetuximab) or OxFU+cetuximab had more dose modifications than those with better renal function.	Creatinine	14-24	CD59 molecule (CD59 blood group)	Homo sapiens	51-57
22935584-9	2012	Patients with creatinine clearance (CrCl) 50-80 ml min(-1) on OxCap(+- cetuximab) or OxFU+cetuximab had more dose modifications than those with better renal function.	crcl	36-40	CD59 molecule (CD59 blood group)	Homo sapiens	51-57
22935584-9	2012	Patients with creatinine clearance (CrCl) 50-80 ml min(-1) on OxCap(+- cetuximab) or OxFU+cetuximab had more dose modifications than those with better renal function.	oxcap	62-67	CD59 molecule (CD59 blood group)	Homo sapiens	51-57
22776430-3	2012	Intent-to-treat analysis showed the 1-year adjusted mean change from baseline in creatinine clearance (Cockcroft-Gault) was significantly higher with sirolimus versus CNI treatment (+3.0 vs. -1.4 mL/min/1.73 m(2) , respectively; p = 0.004).	Creatinine	81-91	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
22776430-3	2012	Intent-to-treat analysis showed the 1-year adjusted mean change from baseline in creatinine clearance (Cockcroft-Gault) was significantly higher with sirolimus versus CNI treatment (+3.0 vs. -1.4 mL/min/1.73 m(2) , respectively; p = 0.004).	Sirolimus	150-159	CD59 molecule (CD59 blood group)	Homo sapiens	199-204
22453252-0	2012	Melphalan 180 mg/m2 can be safely administered as conditioning regimen before an autologous stem cell transplantation (ASCT) in multiple myeloma patients with creatinine clearance 60 mL/min/1.73 m2 or lower with use of palifermin for cytoprotection: results of a phase I trial.	Melphalan	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	186-191
22732111-11	2012	On average, dialysis clearance of sugammadex and rocuronium in blood was 78 and 89 ml min(-1), respectively.	Sugammadex	34-44	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
22732111-11	2012	On average, dialysis clearance of sugammadex and rocuronium in blood was 78 and 89 ml min(-1), respectively.	Rocuronium	49-59	CD59 molecule (CD59 blood group)	Homo sapiens	86-92
22659092-8	2012	However, both compounds underwent UGT-mediated metabolism to 8-O-glucuronides by microsomes from both sources with comparable efficiency; V(max)/K(m) values were from 4.0 to 5.5 mul   min-1   mg protein-1.	8-o-glucuronides	61-77	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
22392689-8	2012	The uptake rate of ozone was found to be 10.21 mL min(-1) in a very good agreement with the theoretical uptake rate (10.32 mL min(-1)).	Ozone	19-24	CD59 molecule (CD59 blood group)	Homo sapiens	50-56
22392689-8	2012	The uptake rate of ozone was found to be 10.21 mL min(-1) in a very good agreement with the theoretical uptake rate (10.32 mL min(-1)).	Ozone	19-24	CD59 molecule (CD59 blood group)	Homo sapiens	126-132
23240214-3	2012	Optimum nitrate reduction rate (1.03 +/- 0.087 x 10(-4) mol x min(-1) x greduc(-1)) was obtained with 5.0% nano-scale Fe/Ni, while only 25% nitrate (1.05 +/- 0.091 x 10(-5) mol x min(-1) x greduc(-1)) was transformed by nano-scale Fe(0) within the same reaction time, which means that these bimetallic nanoparticles are obviously more reactive than monometallic nano-scale Fe(0).	Nitrates	8-15	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
23240214-3	2012	Optimum nitrate reduction rate (1.03 +/- 0.087 x 10(-4) mol x min(-1) x greduc(-1)) was obtained with 5.0% nano-scale Fe/Ni, while only 25% nitrate (1.05 +/- 0.091 x 10(-5) mol x min(-1) x greduc(-1)) was transformed by nano-scale Fe(0) within the same reaction time, which means that these bimetallic nanoparticles are obviously more reactive than monometallic nano-scale Fe(0).	Nitrates	8-15	CD59 molecule (CD59 blood group)	Homo sapiens	179-185
23240214-3	2012	Optimum nitrate reduction rate (1.03 +/- 0.087 x 10(-4) mol x min(-1) x greduc(-1)) was obtained with 5.0% nano-scale Fe/Ni, while only 25% nitrate (1.05 +/- 0.091 x 10(-5) mol x min(-1) x greduc(-1)) was transformed by nano-scale Fe(0) within the same reaction time, which means that these bimetallic nanoparticles are obviously more reactive than monometallic nano-scale Fe(0).	Nitrates	140-147	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
23240214-3	2012	Optimum nitrate reduction rate (1.03 +/- 0.087 x 10(-4) mol x min(-1) x greduc(-1)) was obtained with 5.0% nano-scale Fe/Ni, while only 25% nitrate (1.05 +/- 0.091 x 10(-5) mol x min(-1) x greduc(-1)) was transformed by nano-scale Fe(0) within the same reaction time, which means that these bimetallic nanoparticles are obviously more reactive than monometallic nano-scale Fe(0).	Iron	118-120	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
23240214-3	2012	Optimum nitrate reduction rate (1.03 +/- 0.087 x 10(-4) mol x min(-1) x greduc(-1)) was obtained with 5.0% nano-scale Fe/Ni, while only 25% nitrate (1.05 +/- 0.091 x 10(-5) mol x min(-1) x greduc(-1)) was transformed by nano-scale Fe(0) within the same reaction time, which means that these bimetallic nanoparticles are obviously more reactive than monometallic nano-scale Fe(0).	Iron	118-120	CD59 molecule (CD59 blood group)	Homo sapiens	179-185
23240214-3	2012	Optimum nitrate reduction rate (1.03 +/- 0.087 x 10(-4) mol x min(-1) x greduc(-1)) was obtained with 5.0% nano-scale Fe/Ni, while only 25% nitrate (1.05 +/- 0.091 x 10(-5) mol x min(-1) x greduc(-1)) was transformed by nano-scale Fe(0) within the same reaction time, which means that these bimetallic nanoparticles are obviously more reactive than monometallic nano-scale Fe(0).	Iron	231-233	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
23675276-1	2012	In this work, a reversed-phase liquid chromatographic (RP-LC) method has been developed for the determination of alogliptin (ALG) based on isocratic elution using a mobile phase consisting of potassium dihydrogen phosphate buffer pH (4.6)-acetonitrile (20:80, v/v) at a flow rate of 1 mL min(-1) with UV detection at 215 nm.	alogliptin	113-123	CD59 molecule (CD59 blood group)	Homo sapiens	288-294
22616665-8	2012	The current findings show that a 2:1 maltodextrin/fructose solution (1.8 g min(-1) at 14.4%) ingested throughout the cycle section of a simulated OD triathlon enhances subsequent 10-km run performance in triathletes.	maltodextrin	37-49	CD59 molecule (CD59 blood group)	Homo sapiens	75-81
22453246-1	2012	PURPOSE: Current understanding of exogenous CHO metabolism during cold exposure is limited but suggests that exogenous glucose oxidation reaches a maximum of ~200 mg   min(-1) at a glucose ingestion rate of 400 mg   min(-1).	CAV protocol	44-47	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
22453246-1	2012	PURPOSE: Current understanding of exogenous CHO metabolism during cold exposure is limited but suggests that exogenous glucose oxidation reaches a maximum of ~200 mg   min(-1) at a glucose ingestion rate of 400 mg   min(-1).	CAV protocol	44-47	CD59 molecule (CD59 blood group)	Homo sapiens	216-222
22453246-1	2012	PURPOSE: Current understanding of exogenous CHO metabolism during cold exposure is limited but suggests that exogenous glucose oxidation reaches a maximum of ~200 mg   min(-1) at a glucose ingestion rate of 400 mg   min(-1).	Glucose	119-126	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
22453246-1	2012	PURPOSE: Current understanding of exogenous CHO metabolism during cold exposure is limited but suggests that exogenous glucose oxidation reaches a maximum of ~200 mg   min(-1) at a glucose ingestion rate of 400 mg   min(-1).	Glucose	119-126	CD59 molecule (CD59 blood group)	Homo sapiens	216-222
22453246-1	2012	PURPOSE: Current understanding of exogenous CHO metabolism during cold exposure is limited but suggests that exogenous glucose oxidation reaches a maximum of ~200 mg   min(-1) at a glucose ingestion rate of 400 mg   min(-1).	Glucose	181-188	CD59 molecule (CD59 blood group)	Homo sapiens	168-174
22453246-1	2012	PURPOSE: Current understanding of exogenous CHO metabolism during cold exposure is limited but suggests that exogenous glucose oxidation reaches a maximum of ~200 mg   min(-1) at a glucose ingestion rate of 400 mg   min(-1).	Glucose	181-188	CD59 molecule (CD59 blood group)	Homo sapiens	216-222
22453246-4	2012	Subjects consumed a (13)C-enriched CHO drink ((13)C-enriched glucose and fructose) providing 400 mg   min(-1) of glucose + 400 mg   min(-1) of fructose (GLU + FRU) or 800 mg   min(-1) of glucose alone (GLU) after 60 min of cold exposure.	CAV protocol	35-38	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
22453246-4	2012	Subjects consumed a (13)C-enriched CHO drink ((13)C-enriched glucose and fructose) providing 400 mg   min(-1) of glucose + 400 mg   min(-1) of fructose (GLU + FRU) or 800 mg   min(-1) of glucose alone (GLU) after 60 min of cold exposure.	Glucose	113-120	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
22453246-4	2012	Subjects consumed a (13)C-enriched CHO drink ((13)C-enriched glucose and fructose) providing 400 mg   min(-1) of glucose + 400 mg   min(-1) of fructose (GLU + FRU) or 800 mg   min(-1) of glucose alone (GLU) after 60 min of cold exposure.	Glucose	113-120	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
22453246-5	2012	RESULTS: The peak exogenous CHO oxidation rate was 30% greater in GLU + FRU compared with GLU (209 +- 62 vs 159 +- 42 mg   min(-1), respectively, P &lt; 0.05).	CAV protocol	28-31	CD59 molecule (CD59 blood group)	Homo sapiens	123-129
22453246-6	2012	This contributed to a 16% increase in total CHO oxidation (406 +- 100 vs 351 +- 80 mg   min(-1), respectively, P &lt; 0.05).	CAV protocol	44-47	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
22453246-7	2012	The utilization of endogenous CHO sources was the same between experimental conditions but was nearly 2.5 times lower than values previously reported by our laboratory when only water was ingested (192-197 vs 456 mg   min(-1), respectively).	CAV protocol	30-33	CD59 molecule (CD59 blood group)	Homo sapiens	218-224
22820419-5	2012	When CD59 was ligated, it formed stable oligomer rafts containing up to four CD59 molecules, which triggered intracellular Ca(2+) responses that were dependent on GPI anchorage and cholesterol, suggesting a key part played by transient homodimer rafts.	Cholesterol	181-192	CD59 molecule (CD59 blood group)	Homo sapiens	5-9
22820419-5	2012	When CD59 was ligated, it formed stable oligomer rafts containing up to four CD59 molecules, which triggered intracellular Ca(2+) responses that were dependent on GPI anchorage and cholesterol, suggesting a key part played by transient homodimer rafts.	Cholesterol	181-192	CD59 molecule (CD59 blood group)	Homo sapiens	77-81
22770565-4	2012	The maximum rate of reduction at 355 kHz, of Fe(CN)63-, was 2.6 +- 0.3 muM min-1, whereas for methyl viologen, it was 1.2 +- 0.3 muM min-1 under the conditions used.The difference in the rates is attributed to the reaction of various pyrolytically produced organic radicals with the methyl viologen radical cation.	fe(cn)	45-51	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
22433079-8	2012	RESULTS: Saline loading increased the urinary sodium excretion by 3.6-fold (21-76 mumol min(-1) , P &lt; 0.01).	Sodium Chloride	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
22433079-8	2012	RESULTS: Saline loading increased the urinary sodium excretion by 3.6-fold (21-76 mumol min(-1) , P &lt; 0.01).	Sodium	46-52	CD59 molecule (CD59 blood group)	Homo sapiens	88-94
22464876-10	2012	Acylcarnitines such as glutarylcarnitine were associated inversely with eGFR (-3.73 mL/min/1.73 m(2) per standard deviation [SD] increase, pooled P = 1.8 x 10(-69)).	acylcarnitine	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
22464876-10	2012	Acylcarnitines such as glutarylcarnitine were associated inversely with eGFR (-3.73 mL/min/1.73 m(2) per standard deviation [SD] increase, pooled P = 1.8 x 10(-69)).	glutarylcarnitine	23-40	CD59 molecule (CD59 blood group)	Homo sapiens	87-92
22464876-12	2012	Almost all replicated phenotypes associated with decreased eGFR (&lt;60 mL/min/1.73 m(2); n = 172 cases) in KORA F4: per 1-SD increment, ORs ranged from 0.29-2.06.	kora	108-112	CD59 molecule (CD59 blood group)	Homo sapiens	75-80
22616665-8	2012	The current findings show that a 2:1 maltodextrin/fructose solution (1.8 g min(-1) at 14.4%) ingested throughout the cycle section of a simulated OD triathlon enhances subsequent 10-km run performance in triathletes.	Fructose	50-58	CD59 molecule (CD59 blood group)	Homo sapiens	75-81
22653840-9	2012	CONCLUSIONS: With our modern anesthesia machines, reducing the fresh gas flow of oxygen to 0.3-0.5 L min(-1) and using third-generation inhaled anesthetics provide a reassuringly safe anesthetic technique.	Oxygen	81-87	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
22516622-6	2012	FINDINGS: Ensemble-averaged oxygen uptakes across pedal cadences were higher during stepping (448 (75) ml min(-1)) compared to cycling (422 (54) ml min(-1)).	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	106-112
22516622-6	2012	FINDINGS: Ensemble-averaged oxygen uptakes across pedal cadences were higher during stepping (448 (75) ml min(-1)) compared to cycling (422 (54) ml min(-1)).	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	148-154
22717724-7	2012	Supplemental oxygen should only be used if, despite effective ventilation, the heart rate does not increase above 100  beats  min(-1), or if oxygenation as indicated by pulse oximetry, remains unacceptably low.	Oxygen	13-19	CD59 molecule (CD59 blood group)	Homo sapiens	126-132
22926347-2	2012	Patients with endogenous creatinine clearance     30 mL/min/1.73m2 are introduced into the kidney transplant program.	Creatinine	25-35	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
22991798-10	2012	CONCLUSIONS: We found that more than 0.5 microg x kg(-1) x min(-1) of remifentanil can blunt cardiovascular responses to tracheal intubation without severe cardiovascular depression.	Remifentanil	70-82	CD59 molecule (CD59 blood group)	Homo sapiens	59-65
22531167-5	2012	The maximum CO(2) removal efficiency was 94% at flow rate of 30 mL min(-1), light intensity of 179 mumol m(-2) s(-1) and CO(2) concentration of 10%, implying that the novel gas sparger is a promising alternative for CO(2) removal from CO(2)-enriched air by cultivating microalgae in the photobioreactor.	Carbon Dioxide	12-17	CD59 molecule (CD59 blood group)	Homo sapiens	67-73
22585054-7	2012	Separation of the three compounds was achieved in 10 min by use of 0.01% aqueous acetic acid-MeOH (60:40) as mobile phase at a flow rate of 0.8 mL min(-1).	Acetic Acid	81-92	CD59 molecule (CD59 blood group)	Homo sapiens	147-153
22797101-8	2012	Also, GFR was 79.8 +- 22.3 mL/min/1.73 m2 in the sirolimus group and 70.3 +- 23.6 mL/min/1.73 m2 in the cyclosporine group B (P = .04).	Cyclosporine	104-116	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
22973082-1	2012	This study aims to generate the normalized mean organ dose factors (mGy min(-1) GBq(-1)) to healthy organs during brachytherapy treatment of esophagus, breast, and neck cancers specific to the patient population in India.	GBQ	80-83	CD59 molecule (CD59 blood group)	Homo sapiens	72-78
26472918-3	2012	Mosquitoes are activated by brief exposure to a 1 L min-1 jet of 4% CO2 positioned 10 cm from the release cage.	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	68-71	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
22539359-3	2012	The determination of glycosylphosphatidylinositol (GPI) deficient cells on the erythroid lineage was made with a two-color FCM assay of CD71 and CD59, evaluating the PNH clone on i-RET.	Glycosylphosphatidylinositols	51-54	CD59 molecule (CD59 blood group)	Homo sapiens	145-149
22468766-1	2012	When ingested at high rates (1.8-2.4 g min(-1)) in concentrated solutions, carbohydrates absorbed by multiple (e.g., fructose and glucose) vs. single intestinal transporters can increase exogenous carbohydrate oxidation and endurance performance, but their effect when ingested at lower, more realistic, rates during intermittent high-intensity endurance competition and trials is unknown.	Carbohydrates	75-88	CD59 molecule (CD59 blood group)	Homo sapiens	39-46
22468766-1	2012	When ingested at high rates (1.8-2.4 g min(-1)) in concentrated solutions, carbohydrates absorbed by multiple (e.g., fructose and glucose) vs. single intestinal transporters can increase exogenous carbohydrate oxidation and endurance performance, but their effect when ingested at lower, more realistic, rates during intermittent high-intensity endurance competition and trials is unknown.	Fructose	117-125	CD59 molecule (CD59 blood group)	Homo sapiens	39-46
22468766-1	2012	When ingested at high rates (1.8-2.4 g min(-1)) in concentrated solutions, carbohydrates absorbed by multiple (e.g., fructose and glucose) vs. single intestinal transporters can increase exogenous carbohydrate oxidation and endurance performance, but their effect when ingested at lower, more realistic, rates during intermittent high-intensity endurance competition and trials is unknown.	Glucose	130-137	CD59 molecule (CD59 blood group)	Homo sapiens	39-46
22468766-1	2012	When ingested at high rates (1.8-2.4 g min(-1)) in concentrated solutions, carbohydrates absorbed by multiple (e.g., fructose and glucose) vs. single intestinal transporters can increase exogenous carbohydrate oxidation and endurance performance, but their effect when ingested at lower, more realistic, rates during intermittent high-intensity endurance competition and trials is unknown.	Carbohydrates	75-87	CD59 molecule (CD59 blood group)	Homo sapiens	39-46
22528166-8	2012	A phenylephrine infusion (25-50 mug x min(-1)) appears to be more effective than phenylephrine boluses to prevent hypotension, and nausea and vomiting.	Phenylephrine	2-15	CD59 molecule (CD59 blood group)	Homo sapiens	38-44
22503397-6	2012	The mean decline in estimated glomerular filtration rate (eGFR) following the first cycle of ifosfamide was 15 ml/min/1.73 m(2).	Ifosfamide	93-103	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
22495590-5	2012	The glucose infusion rate (adjusted for fat free mass and circulating insulin concentration) required to maintain blood glucose concentration at 5 mmol l-1 during administration of insulin was decreased in hypoxia compared with normoxia (225 +- 23 vs. 128 +- 30 nmol (kg fat free mass)-1 pmol l-1 min-1; P =0.03), and unchanged during normoxia and sympathetic inhibition (219 +- 19; P =0.86) and hypoxia and sympathetic inhibition (169 +- 23; P =0.23).	Glucose	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	297-302
22746016-5	2012	Landiolol infusion was started at a rate of 3 microg x kg(-1) x min(-1) for patients in L group and LO group, and olprinone infusion was administered at a rate of 0.2 microg x kg(-1) x min(-1) for 90 minutes followed by 0.1 microg x kg(-1) x min(-1) for patients in LO group.	landiolol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	64-70
22362674-6	2012	The maximum possible concentration of sevoflurane that can be delivered by the DDV2 was measured at a continuous flow rate of 8 litre min(-1) at 20, 30, and 40 C. RESULTS: Concentrations of sevoflurane delivered in the draw-over mode were within 0.5% of dialled setting up to 30 C. Above this temperature, higher levels of vapour were delivered.	Sevoflurane	38-49	CD59 molecule (CD59 blood group)	Homo sapiens	134-140
22388705-9	2012	RESULTS: The concentration of sevoflurane reached 5 parts per million in the Fabius CE machines after an mean (SD) of 140 min (46) at a fresh gas flow (FGF) of 10 l min(-1).	Sevoflurane	30-41	CD59 molecule (CD59 blood group)	Homo sapiens	165-171
22388705-11	2012	The concentration of sevoflurane reached 5 parts per million in the Zeus machines after an mean (SD) of 85 min (6) at a fresh gas flow of 10 l min(-1).	Sevoflurane	21-32	CD59 molecule (CD59 blood group)	Homo sapiens	143-149
22403352-9	2012	Pulsatile flow was not associated with augmentation of free hemoglobin production and was paralleled by improved oxygen consumption from 70 +- 14 to 82 +- 16 ml min(-1) m(-2) (P = 0.01) at the end of aortic cross-clamping.	Oxygen	113-119	CD59 molecule (CD59 blood group)	Homo sapiens	161-167
22033515-5	2012	Peak oxygen uptake (V O2peak) increased by ~35% from before (0.64 L min-1 or 11.4 mL kg min-1) to 1 month (0.88 L min-1 or 15.7 mL kg min-1) of treatment and did not significantly change thereafter.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	68-73
22033515-5	2012	Peak oxygen uptake (V O2peak) increased by ~35% from before (0.64 L min-1 or 11.4 mL kg min-1) to 1 month (0.88 L min-1 or 15.7 mL kg min-1) of treatment and did not significantly change thereafter.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
22033515-5	2012	Peak oxygen uptake (V O2peak) increased by ~35% from before (0.64 L min-1 or 11.4 mL kg min-1) to 1 month (0.88 L min-1 or 15.7 mL kg min-1) of treatment and did not significantly change thereafter.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
22033515-5	2012	Peak oxygen uptake (V O2peak) increased by ~35% from before (0.64 L min-1 or 11.4 mL kg min-1) to 1 month (0.88 L min-1 or 15.7 mL kg min-1) of treatment and did not significantly change thereafter.	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
22456504-6	2012	Moreover, accumulation of lysophospholipids induced by a lysophospholipid acyltransferase inhibitor extensively vesiculated CD59-containing endosomes.	Lysophospholipids	26-43	CD59 molecule (CD59 blood group)	Homo sapiens	124-128
22508204-6	2012	Adrenaline (mean dose: 0.06 mug/kg x min-1) was required in seven patients from Group B but in none of the Group A patients on initial separation from CPB (P&lt; 0.05).	Epinephrine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	37-42
22491199-6	2012	Treatment with intravenous glucose infusion improved maximal oxygen uptake from 23 to 27 mL x kg(-1) x min(-1), and maximal workload from 75 to 100 W. CONCLUSIONS: These results demonstrate that in addition to fixed weakness, neutral lipid storage disease with myopathy is also characterized by a profound block in fat oxidation, which limits exercise tolerance.	Glucose	27-34	CD59 molecule (CD59 blood group)	Homo sapiens	103-109
21999196-14	2012	At t(max) at 8 h post dose, nortriptyline increased the heart rate response to posture change in all subjects with mean (95% CI) Delta heart rate values of 7.4 (3.6, 11.3) beats min(-1) on active standing (P = 0.0009) and 4.8 (2.0, 7.6) beats min(-1) on head-up tilt (P = 0.002), but no difference was observed between haplotype groups.	Nortriptyline	28-41	CD59 molecule (CD59 blood group)	Homo sapiens	178-184
21999196-14	2012	At t(max) at 8 h post dose, nortriptyline increased the heart rate response to posture change in all subjects with mean (95% CI) Delta heart rate values of 7.4 (3.6, 11.3) beats min(-1) on active standing (P = 0.0009) and 4.8 (2.0, 7.6) beats min(-1) on head-up tilt (P = 0.002), but no difference was observed between haplotype groups.	Nortriptyline	28-41	CD59 molecule (CD59 blood group)	Homo sapiens	243-249
22275267-8	2012	The L-GLU adsorption capacity of the cryogel decreased drastically from 11.3 to 6.4 mumol g(-1) as the flow rate increased from 0.5 to 4.0 mL min(-1) .	Glutamic Acid	4-9	CD59 molecule (CD59 blood group)	Homo sapiens	142-148
22369766-9	2012	The mean ventilatory response was 5.8 litre min(-2) starting from air breathing and 4.5 litre min(-2) with oxygen breathing.	Oxygen	107-113	CD59 molecule (CD59 blood group)	Homo sapiens	94-100
22720419-2	2012	An ozone dosage of 57 mg min(-1) was found to be optimal for the degradation of both endosulfan (89%) and lindane (43%).	Endosulfan	85-95	CD59 molecule (CD59 blood group)	Homo sapiens	25-31
22720419-2	2012	An ozone dosage of 57 mg min(-1) was found to be optimal for the degradation of both endosulfan (89%) and lindane (43%).	Hexachlorocyclohexane	106-113	CD59 molecule (CD59 blood group)	Homo sapiens	25-31
22720419-7	2012	While for initial lindane concentrations of 5, 7.5 and 10 ppm, the observed rate constants were 0.0243, 0.0333 and 0.056 min(-1), respectively.	Hexachlorocyclohexane	18-25	CD59 molecule (CD59 blood group)	Homo sapiens	121-127
21885393-5	2012	Similarly, Hi-NPPV induced a greater reduction in the pressure-time product of the diaphragm per minute from 323 +- 149 cmH(2)O   s   min(-1) during SB to 132 +- 139 cmH(2)O   s   min(-1) during Li-NPPV and 40 +- 69 cmH(2)O   s   min(-1) during Hi-NPPV, while in nine out of 15 patients, it completely abolished SB activity.	hi-nppv	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	134-140
21885393-5	2012	Similarly, Hi-NPPV induced a greater reduction in the pressure-time product of the diaphragm per minute from 323 +- 149 cmH(2)O   s   min(-1) during SB to 132 +- 139 cmH(2)O   s   min(-1) during Li-NPPV and 40 +- 69 cmH(2)O   s   min(-1) during Hi-NPPV, while in nine out of 15 patients, it completely abolished SB activity.	hi-nppv	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	180-186
21885393-5	2012	Similarly, Hi-NPPV induced a greater reduction in the pressure-time product of the diaphragm per minute from 323 +- 149 cmH(2)O   s   min(-1) during SB to 132 +- 139 cmH(2)O   s   min(-1) during Li-NPPV and 40 +- 69 cmH(2)O   s   min(-1) during Hi-NPPV, while in nine out of 15 patients, it completely abolished SB activity.	hi-nppv	11-18	CD59 molecule (CD59 blood group)	Homo sapiens	180-186
21885393-5	2012	Similarly, Hi-NPPV induced a greater reduction in the pressure-time product of the diaphragm per minute from 323 +- 149 cmH(2)O   s   min(-1) during SB to 132 +- 139 cmH(2)O   s   min(-1) during Li-NPPV and 40 +- 69 cmH(2)O   s   min(-1) during Hi-NPPV, while in nine out of 15 patients, it completely abolished SB activity.	Antimony	149-151	CD59 molecule (CD59 blood group)	Homo sapiens	134-140
22333933-8	2012	A CL(Cr)&gt;120 mL/min/1.73 m(2) had a sensitivity of 26%, a specificity of 94% and an 84% positive predictive value of 84% for vancomycin concentrations &lt;20 mug/mL.	Vancomycin	128-138	CD59 molecule (CD59 blood group)	Homo sapiens	19-24
22278428-8	2012	RESULTS: Glucose disappearance increased from baseline (1.85 mg/kg   min-1) compared with 24 h (2.01 min/kg   min-1) after HyEx60 (P = 0.031).	Glucose	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	69-74
22416235-6	2012	RESULTS: Mean peak oxygen uptake [Formula: see text] increased from 34 +- 7 to 37 +- 7 ml kg(-1) min(-1) in training group (p &lt; 0.001) and did not change in control group (from 34 +- 7 to 34 +- 7 ml kg(-1) min(-1)).	Oxygen	19-25	CD59 molecule (CD59 blood group)	Homo sapiens	97-103
22099229-4	2012	The plate height values were no more than 24 mum for the flow rate between 0.5 and 5.4 mm s-1 (0.3-3.5 mL min-1), which proved the excellent separation efficiency of Click TE-Cys stationary phase.	te-cys	172-178	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
22288523-6	2012	An approximate second order rate constant of 11.331 M(-1) min(-1) at Na(2)CO(3) dosage of 20 g/L was found for the tested wastewater.	sodium carbonate	69-79	CD59 molecule (CD59 blood group)	Homo sapiens	58-64
22228264-6	2012	Experiments performed with toluene at concentrations of ~1 ppm gave a constant sampling rate of 9.1 mL min(-1) for up to 30 min, which is within 2% of theoretical predictions and corresponds to a linear dynamic mass uptake range of ~1 mug.	Toluene	27-34	CD59 molecule (CD59 blood group)	Homo sapiens	103-109
22228264-7	2012	The cavity membrane could be heated to 250  C in 0.23 s with 1 W of applied power and, with 50 mL min(-1) of suction flow provided by a downstream pump, yielded &gt;95% desorption/injection efficiency of toluene samples over an 8-fold range of captured mass.	Toluene	204-211	CD59 molecule (CD59 blood group)	Homo sapiens	98-104
22244141-3	2012	The results showed that at a flow rate of 10 mL min(-1) for the sample solutions (100mL), the PAHs could be adsorbed on the sulfur microparticles and then eluted by 2.0 mL of acetonitrile.	acetonitrile	175-187	CD59 molecule (CD59 blood group)	Homo sapiens	48-54
22159026-5	2012	Nitrogen bubbles were consistently removed at a rate of 0.14 muL min(-1).	Nitrogen	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	65-71
22159026-9	2012	Scalability of the design was demonstrated by realizing eight parallel traps at a total removal rate of 0.9 muL min(-1) (measured for nitrogen).	Nitrogen	134-142	CD59 molecule (CD59 blood group)	Homo sapiens	112-118
22028316-4	2012	The kinetics of the haloperidol O-glucuronidation in HLM was monophasic with K(m) and V(max) values of 85 muM and 3.2 nmol   min-1   mg-1, respectively.	Haloperidol	20-31	CD59 molecule (CD59 blood group)	Homo sapiens	125-137
22146314-10	2012	Mean estimated creatinine clearance 1 year posttransplant was 93.2+-33.3 mL/min/1.73 m(2).	Creatinine	15-25	CD59 molecule (CD59 blood group)	Homo sapiens	76-81
22031625-7	2012	In addition, the estimated hepatic clearance value for O6-benzylguanine was within ~80% of the observed total clearance in humans after intravenous administration (15 ml   min-1   kg-1), indicating a reasonable level of quantitative activity from this in vitro system.	O(6)-benzylguanine	55-71	CD59 molecule (CD59 blood group)	Homo sapiens	172-184
22309417-9	2012	The glomerular filtration rate, measured by technetium Tc-99m-diethylenetriamine penta-acetic aerosol scintigraphy, improved from 27.4 +- 6.8 mL/min/1.73 m(2) before conversion to 43.3 +- 6.3 mL/min/1.73 m(2) at final follow-up.	Technetium	44-61	CD59 molecule (CD59 blood group)	Homo sapiens	145-150
21986583-13	2012	The sampling rates for the 11 VOCs were determined and ranged from 3.3 mL min(-1) for styrene and 2-ethyl-1-hexanol to 11.7 mL min(-1) for benzene.	Benzene	139-146	CD59 molecule (CD59 blood group)	Homo sapiens	127-133
22195982-1	2012	The CO(2) fixation ability of N-heterocyclic carbenes (NHC) has been assessed on the basis of electronic and steric properties of the N- and C-substituents, measured in terms of molecular electrostatic potential minimum, observed at the carbene lone pair region of NHC (V(min1)) as well as at the carboxylate region of the NHC-CO(2) adduct (V(min2)).	co(2)	4-9	CD59 molecule (CD59 blood group)	Homo sapiens	272-276
22195982-1	2012	The CO(2) fixation ability of N-heterocyclic carbenes (NHC) has been assessed on the basis of electronic and steric properties of the N- and C-substituents, measured in terms of molecular electrostatic potential minimum, observed at the carbene lone pair region of NHC (V(min1)) as well as at the carboxylate region of the NHC-CO(2) adduct (V(min2)).	co(2)	4-9	CD59 molecule (CD59 blood group)	Homo sapiens	343-347
22195982-1	2012	The CO(2) fixation ability of N-heterocyclic carbenes (NHC) has been assessed on the basis of electronic and steric properties of the N- and C-substituents, measured in terms of molecular electrostatic potential minimum, observed at the carbene lone pair region of NHC (V(min1)) as well as at the carboxylate region of the NHC-CO(2) adduct (V(min2)).	carbene	45-53	CD59 molecule (CD59 blood group)	Homo sapiens	272-276
22195982-1	2012	The CO(2) fixation ability of N-heterocyclic carbenes (NHC) has been assessed on the basis of electronic and steric properties of the N- and C-substituents, measured in terms of molecular electrostatic potential minimum, observed at the carbene lone pair region of NHC (V(min1)) as well as at the carboxylate region of the NHC-CO(2) adduct (V(min2)).	carbene	45-53	CD59 molecule (CD59 blood group)	Homo sapiens	343-347
22195982-1	2012	The CO(2) fixation ability of N-heterocyclic carbenes (NHC) has been assessed on the basis of electronic and steric properties of the N- and C-substituents, measured in terms of molecular electrostatic potential minimum, observed at the carbene lone pair region of NHC (V(min1)) as well as at the carboxylate region of the NHC-CO(2) adduct (V(min2)).	carbene	45-52	CD59 molecule (CD59 blood group)	Homo sapiens	272-276
22195982-1	2012	The CO(2) fixation ability of N-heterocyclic carbenes (NHC) has been assessed on the basis of electronic and steric properties of the N- and C-substituents, measured in terms of molecular electrostatic potential minimum, observed at the carbene lone pair region of NHC (V(min1)) as well as at the carboxylate region of the NHC-CO(2) adduct (V(min2)).	carbene	45-52	CD59 molecule (CD59 blood group)	Homo sapiens	343-347
22126227-1	2012	Diastereoselective trans-2,5-disubstituted amino acids derived diverse morpholines, piperazines and thiomorpholines were prepared in 30 min-1 h with high yields through iodine-mediated 6-exotrig type cyclization from a single common synthetic intermediate.	trans-2,5-disubstituted amino acids	19-54	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
22126227-1	2012	Diastereoselective trans-2,5-disubstituted amino acids derived diverse morpholines, piperazines and thiomorpholines were prepared in 30 min-1 h with high yields through iodine-mediated 6-exotrig type cyclization from a single common synthetic intermediate.	Morpholines	71-82	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
22126227-1	2012	Diastereoselective trans-2,5-disubstituted amino acids derived diverse morpholines, piperazines and thiomorpholines were prepared in 30 min-1 h with high yields through iodine-mediated 6-exotrig type cyclization from a single common synthetic intermediate.	thiamorpholine	100-115	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
22126227-1	2012	Diastereoselective trans-2,5-disubstituted amino acids derived diverse morpholines, piperazines and thiomorpholines were prepared in 30 min-1 h with high yields through iodine-mediated 6-exotrig type cyclization from a single common synthetic intermediate.	Iodine	169-175	CD59 molecule (CD59 blood group)	Homo sapiens	136-141
22481098-5	2012	The maximum dose of epoprostenol given was 55.3+-10.7 ng kg(-1) min(-1) (range, 21.0-110.5 ng kg(-1) min(-1)).	Epoprostenol	20-32	CD59 molecule (CD59 blood group)	Homo sapiens	64-70
22642155-3	2012	At a flow rate of 2.0 ml x min(-1), a complete determination of phenobarbital, including sampling and washing, could be accomplished in 0.5 min, offering the sampling efficiency of 120 h(-1) accordingly.	Phenobarbital	64-77	CD59 molecule (CD59 blood group)	Homo sapiens	27-33
22481098-5	2012	The maximum dose of epoprostenol given was 55.3+-10.7 ng kg(-1) min(-1) (range, 21.0-110.5 ng kg(-1) min(-1)).	Epoprostenol	20-32	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
22642361-4	2012	Recently, we developed a specific and potent hCD59 inhibitor, His-tagged ILYd4, which consists of 30 amino acid sequences extending from the N-terminus of ILYd4.	Histidine	62-65	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
21890735-4	2011	In particular, one proluciferin acetal has demonstrated sensitive and selective CYP3A4-catalyzed oxidation to a luciferin ester-K(m) and k(cat) are 2.88 muM and 5.87 pmol metabolite   min(-1)   pmol enzyme(-1), respectively.	proluciferin acetal	19-38	CD59 molecule (CD59 blood group)	Homo sapiens	184-190
22494379-6	2012	Based on the model obtained in this study, optimum H(2)O(2) dosage rate and Fe(3+) dosage were found to be 4 mg L(-1) min(-1) and 20 mg L(-1), respectively, for 51 mg L(-1) of carbofuran concentration.	Water	51-56	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
22494379-6	2012	Based on the model obtained in this study, optimum H(2)O(2) dosage rate and Fe(3+) dosage were found to be 4 mg L(-1) min(-1) and 20 mg L(-1), respectively, for 51 mg L(-1) of carbofuran concentration.	ferric sulfate	76-82	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
22876780-3	2012	Mean power during the designated start section (68.5 +- 5.5 s) was 481 +- 122 W, incurring an O2 deficit of 1.58 +- 0.67 L - min(-1) highlighting a significant initial anaerobic (32.4 +- 10.2%) contribution.	Oxygen	94-96	CD59 molecule (CD59 blood group)	Homo sapiens	125-131
23037894-0	2012	Increased time exposure to tenofovir is associated with a greater decrease in estimated glomerular filtration rate in HIV patients with kidney function of less than 60 ml/min/1.73 m2.	Tenofovir	27-36	CD59 molecule (CD59 blood group)	Homo sapiens	171-176
22188591-13	2011	PERLD1 is involved in the modification of the glycosylphosphatidylinositol anchors for cell surface markers such as CD48 and CD59 which are known to play multiple roles in T-cell activation and proliferation.	Glycosylphosphatidylinositols	46-74	CD59 molecule (CD59 blood group)	Homo sapiens	125-129
22177085-11	2011	Insulin-sensitivity significantly increased in the HCF-group from week-6 (baseline M-value 3.8 +- 0.4 vs 4.3 +- 0.4 mg kg-1 min-1, p = 0.015; full model 0-18-weeks, treatment-x-time interaction, p = 0.046).	hcf	51-54	CD59 molecule (CD59 blood group)	Homo sapiens	124-129
21994916-4	2011	Under the optimum SPE conditions, all target analytes in 50 mL environmental water samples can be completely extracted by 1.5 mg Nylon 6 nanofibers mat at flow rate of 3.0 mL min(-1) and easily eluted by passage of 500 muL mobile phase.	Water	77-82	CD59 molecule (CD59 blood group)	Homo sapiens	175-181
21994916-4	2011	Under the optimum SPE conditions, all target analytes in 50 mL environmental water samples can be completely extracted by 1.5 mg Nylon 6 nanofibers mat at flow rate of 3.0 mL min(-1) and easily eluted by passage of 500 muL mobile phase.	nylon 6	129-136	CD59 molecule (CD59 blood group)	Homo sapiens	175-181
21890735-4	2011	In particular, one proluciferin acetal has demonstrated sensitive and selective CYP3A4-catalyzed oxidation to a luciferin ester-K(m) and k(cat) are 2.88 muM and 5.87 pmol metabolite   min(-1)   pmol enzyme(-1), respectively.	luciferin ester	112-127	CD59 molecule (CD59 blood group)	Homo sapiens	184-190
21883744-4	2011	Twenty-eight patients with heart transplantation were switched from CNI regimen to everolimus and mycophenolate, when cGFR was &lt;75 mL/min/1.73 m(2).	Mycophenolic Acid	98-111	CD59 molecule (CD59 blood group)	Homo sapiens	137-142
21468747-8	2011	Total CHO oxidation rate was 17.2 +- 3.1 mg x kg FFM(-1 )x min(-1) and 13.2 +- 6.1 mg x kg FFM(-1) x min(-1) during CARB and CONT, respectively (p = 0.06).	CAV protocol	6-9	CD59 molecule (CD59 blood group)	Homo sapiens	59-65
22021246-9	2011	Myocardial oxygen consumption averaged 0.137 +- 0.057 mL min(-1) g(-1) in carriers and was not significantly different from controls (0.125 +- 0.043 mL min(-1) g(-1), P= 0.29).	Oxygen	11-17	CD59 molecule (CD59 blood group)	Homo sapiens	57-63
21992070-6	2011	RESULTS: Plasma clearances of 51Cr-EDTA for all patients ranged between 2.1 and 30.8 mL/min/1.73 m2, whereas urinary 51Cr-EDTA clearances ranged from 0.7-20.0 mL/min/1.73 m2.	51cr-edta	30-39	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
21992070-6	2011	RESULTS: Plasma clearances of 51Cr-EDTA for all patients ranged between 2.1 and 30.8 mL/min/1.73 m2, whereas urinary 51Cr-EDTA clearances ranged from 0.7-20.0 mL/min/1.73 m2.	Chromium-51	30-34	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
21992070-6	2011	RESULTS: Plasma clearances of 51Cr-EDTA for all patients ranged between 2.1 and 30.8 mL/min/1.73 m2, whereas urinary 51Cr-EDTA clearances ranged from 0.7-20.0 mL/min/1.73 m2.	Edetic Acid	35-39	CD59 molecule (CD59 blood group)	Homo sapiens	88-93
21918174-0	2011	rILYd4, a human CD59 inhibitor, enhances complement-dependent cytotoxicity of ofatumumab against rituximab-resistant B-cell lymphoma cells and chronic lymphocytic leukemia.	rilyd4	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	16-20
22092810-5	2011	The detoxification system is constitutively expressed with a specific activity of 352 (+-18) nmol NADH oxidized min(-1)  (mg protein)(-1) .	NAD	98-102	CD59 molecule (CD59 blood group)	Homo sapiens	112-118
22242479-4	2011	The experiment results showed that the emission peaks of N2 (C3 pi(u)) reached the maximum at the nitrogen flow rate of 80 mL x min(-1) with increasing addition of nitrogen, the gas temperature increased from 342 to 523 K when the input power increased from 30 to 210 W, and the vibrational temperature changed slightly when the gas flow rate of nitrogen increased from 30 to 140 mL x min(-1).	Nitrogen	98-106	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
22242479-4	2011	The experiment results showed that the emission peaks of N2 (C3 pi(u)) reached the maximum at the nitrogen flow rate of 80 mL x min(-1) with increasing addition of nitrogen, the gas temperature increased from 342 to 523 K when the input power increased from 30 to 210 W, and the vibrational temperature changed slightly when the gas flow rate of nitrogen increased from 30 to 140 mL x min(-1).	Nitrogen	164-172	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
22242479-4	2011	The experiment results showed that the emission peaks of N2 (C3 pi(u)) reached the maximum at the nitrogen flow rate of 80 mL x min(-1) with increasing addition of nitrogen, the gas temperature increased from 342 to 523 K when the input power increased from 30 to 210 W, and the vibrational temperature changed slightly when the gas flow rate of nitrogen increased from 30 to 140 mL x min(-1).	Nitrogen	164-172	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
22295630-9	2011	When the rotate speed was (210 +/- 5) r x min(-1), the desorption of mercury significantly increased, thereby the rotate speed had an effect on the release of mercury.	Mercury	69-76	CD59 molecule (CD59 blood group)	Homo sapiens	42-48
22295630-9	2011	When the rotate speed was (210 +/- 5) r x min(-1), the desorption of mercury significantly increased, thereby the rotate speed had an effect on the release of mercury.	Mercury	159-166	CD59 molecule (CD59 blood group)	Homo sapiens	42-48
22035125-2	2011	We present the design and evaluation of a high-flow (16.7 L min-1) countercurrent parallel-plate membrane diffusion denuder that has high removal efficiencies for both non-reactive gases such as carbon monoxide (89%), as well as volatile organic compounds (80-85%) from an automobile exhaust.	Carbon Monoxide	195-210	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
21824817-7	2011	Optimum conditions were determined as 240 bar, 41  C, 4 g min-1 CO2 flow and 150 min of process duration yielding 67.7% (29,728 mumol/ml/min) higher activity than the untreated enzyme providing fundamental basis for enzymatic applications.	Carbon Dioxide	64-67	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
21909232-3	2011	In the 1:2 molar ratio mixture of choline chloride/glycerol containing 3% (v/v) water, cross-linked subtilisin exhibited an excellent activity (2.9 mumo l min(-1) g(-1)) in conjunction with a selectivity of 98% in the transesterification reaction of N-acetyl-L-phenylalanine ethyl ester with 1-propanol.	Choline	34-50	CD59 molecule (CD59 blood group)	Homo sapiens	155-161
21909232-3	2011	In the 1:2 molar ratio mixture of choline chloride/glycerol containing 3% (v/v) water, cross-linked subtilisin exhibited an excellent activity (2.9 mumo l min(-1) g(-1)) in conjunction with a selectivity of 98% in the transesterification reaction of N-acetyl-L-phenylalanine ethyl ester with 1-propanol.	Glycerol	51-59	CD59 molecule (CD59 blood group)	Homo sapiens	155-161
22012496-14	2011	RESULTS: Oxygen consumption during spring-loaded-crutch ambulation (17.88 +- 2.13 mL   kg-1   min-1) was 6.2% greater (P = .015; effect size [ES] = .50) than during traditional axillary-crutch ambulation (16.84 +- 2.08 mL   kg-1   min-1).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	94-99
22012496-14	2011	RESULTS: Oxygen consumption during spring-loaded-crutch ambulation (17.88 +- 2.13 mL   kg-1   min-1) was 6.2% greater (P = .015; effect size [ES] = .50) than during traditional axillary-crutch ambulation (16.84 +- 2.08 mL   kg-1   min-1).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	231-236
22099812-9	2011	Mean creatinine clearance at 1 year was 65 versus 50 mL/min/1.73 m(2) (P = .5) and at 5 years, 60 versus 55 mL/min/1.73 m(2) (P = .1) for the single versus multiple renal arteries groups, respectively.	Creatinine	5-15	CD59 molecule (CD59 blood group)	Homo sapiens	56-61
21869988-2	2011	A prototype system was built to achieve a flow rate of 1 mL min(-1) and 0.26 mL min(-1) for helium and dry air, respectively, when they were used as carrier gas.	Helium	92-98	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
21869988-2	2011	A prototype system was built to achieve a flow rate of 1 mL min(-1) and 0.26 mL min(-1) for helium and dry air, respectively, when they were used as carrier gas.	Helium	92-98	CD59 molecule (CD59 blood group)	Homo sapiens	80-86
21918174-3	2011	Previously, we have shown that the potent CD59 inhibitor rILYd4 sensitizes rituximab-resistant lymphoma cells to rituximab-mediated CDC.	rilyd4	57-63	CD59 molecule (CD59 blood group)	Homo sapiens	42-46
21880355-14	2011	Processing the Empress II at a rate slower than recommended 60 C min-1 or long isothermal hold at the maximal processing temperature 920 C can cause crystallization of lithium metasilicate and cristobalite instead of lithium disilicate as major phase.	Lithium	168-175	CD59 molecule (CD59 blood group)	Homo sapiens	65-70
21807617-8	2011	Vitamin D deficient male and female offspring had a 10-fold lower serum 25-hydroxyvitamin D (P &lt; 0.0001) and markedly elevated blood pressures (11-20 mmHg, P &lt; 0.001) and heart rates (21-40 beats min(-1), P &lt; 0.02) than control fed offspring.	Vitamin D	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	202-208
21407132-8	2011	Nitrate supplementation significantly reduced VO(2peak)(nitrate = 4.64 +- 0.35 L min(-1), placebo = 4.82 +- 0.33 L min(-1), P = 0.010) and the ratio between VO(2) and power at maximal intensity (nitrate = 11.2 +- 1.1 mL min(-1) W(-1), placebo = 11.8 +- 1.1 mL min(-1) W(-1), P = 0.031).	Nitrates	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
21407132-8	2011	Nitrate supplementation significantly reduced VO(2peak)(nitrate = 4.64 +- 0.35 L min(-1), placebo = 4.82 +- 0.33 L min(-1), P = 0.010) and the ratio between VO(2) and power at maximal intensity (nitrate = 11.2 +- 1.1 mL min(-1) W(-1), placebo = 11.8 +- 1.1 mL min(-1) W(-1), P = 0.031).	Nitrates	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
21407132-8	2011	Nitrate supplementation significantly reduced VO(2peak)(nitrate = 4.64 +- 0.35 L min(-1), placebo = 4.82 +- 0.33 L min(-1), P = 0.010) and the ratio between VO(2) and power at maximal intensity (nitrate = 11.2 +- 1.1 mL min(-1) W(-1), placebo = 11.8 +- 1.1 mL min(-1) W(-1), P = 0.031).	Nitrates	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
21407132-8	2011	Nitrate supplementation significantly reduced VO(2peak)(nitrate = 4.64 +- 0.35 L min(-1), placebo = 4.82 +- 0.33 L min(-1), P = 0.010) and the ratio between VO(2) and power at maximal intensity (nitrate = 11.2 +- 1.1 mL min(-1) W(-1), placebo = 11.8 +- 1.1 mL min(-1) W(-1), P = 0.031).	Nitrates	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	115-121
21407132-8	2011	Nitrate supplementation significantly reduced VO(2peak)(nitrate = 4.64 +- 0.35 L min(-1), placebo = 4.82 +- 0.33 L min(-1), P = 0.010) and the ratio between VO(2) and power at maximal intensity (nitrate = 11.2 +- 1.1 mL min(-1) W(-1), placebo = 11.8 +- 1.1 mL min(-1) W(-1), P = 0.031).	Nitrates	56-63	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
21850721-8	2011	The highest oxygen permeation rate achieved a value of 2.02 cc min(-1) cm(-2) at 1273 K for Sr(3)Ti(0.8)Co(1.2)O(7-delta).	Oxygen	12-18	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
21850721-8	2011	The highest oxygen permeation rate achieved a value of 2.02 cc min(-1) cm(-2) at 1273 K for Sr(3)Ti(0.8)Co(1.2)O(7-delta).	sr(3)	92-97	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
21850721-8	2011	The highest oxygen permeation rate achieved a value of 2.02 cc min(-1) cm(-2) at 1273 K for Sr(3)Ti(0.8)Co(1.2)O(7-delta).	Cobalt	104-106	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
21795683-9	2011	Ratios of V(max) (pmol/oocyte   min(-1)):K(m) (mm), a measure of transport efficiency, were 86, 177, and 120 for hypoxantine, thymine, and adenine, respectively, compared with 265 for uridine.	hypoxantine	113-124	CD59 molecule (CD59 blood group)	Homo sapiens	32-38
21795683-9	2011	Ratios of V(max) (pmol/oocyte   min(-1)):K(m) (mm), a measure of transport efficiency, were 86, 177, and 120 for hypoxantine, thymine, and adenine, respectively, compared with 265 for uridine.	Thymine	126-133	CD59 molecule (CD59 blood group)	Homo sapiens	32-38
21795683-9	2011	Ratios of V(max) (pmol/oocyte   min(-1)):K(m) (mm), a measure of transport efficiency, were 86, 177, and 120 for hypoxantine, thymine, and adenine, respectively, compared with 265 for uridine.	Adenine	139-146	CD59 molecule (CD59 blood group)	Homo sapiens	32-38
21842834-4	2011	A turnover rate of up to 43 x 10(-4) min(-1) was previously observed for cleavage of the glycosidic bond in selected p-nitrophenylglycosides with a binuclear, low molecular weight catalyst; by contrast, the same reaction is more than 1 order of magnitude faster and has a turnover rate of up to 380 x 10(-4) min(-1) when using the prepared macromolecular catalyst.	p-nitrophenylglycosides	117-140	CD59 molecule (CD59 blood group)	Homo sapiens	37-43
21842834-4	2011	A turnover rate of up to 43 x 10(-4) min(-1) was previously observed for cleavage of the glycosidic bond in selected p-nitrophenylglycosides with a binuclear, low molecular weight catalyst; by contrast, the same reaction is more than 1 order of magnitude faster and has a turnover rate of up to 380 x 10(-4) min(-1) when using the prepared macromolecular catalyst.	p-nitrophenylglycosides	117-140	CD59 molecule (CD59 blood group)	Homo sapiens	308-314
21911814-9	2011	Total systemic oxygen delivery was markedly reduced in the hybrid palliation (Blalock-Tausig shunt 591, right ventricle-to-pulmonary artery shunt 640, and hybrid 475 mL   min(-1)   m(-2)).	Oxygen	15-21	CD59 molecule (CD59 blood group)	Homo sapiens	171-177
21310760-7	2011	Estimated GFR decreased significantly with imatinib treatment duration; the mean decrease per year was 2.77 ml/min/1.73 m(2) (P &lt; 0.001); 12% of patients developed chronic renal failure.	Imatinib Mesylate	43-51	CD59 molecule (CD59 blood group)	Homo sapiens	111-116
21417608-6	2011	RESULTS: A rate constant of morphine disappearance from the donor phase of the in vitro model of 1.8 x 10(-2) min(-1) was calculated, independently of the different release media used.	Morphine	28-36	CD59 molecule (CD59 blood group)	Homo sapiens	110-116
21685245-11	2011	Intrinsic hepatic clearance was estimated to be 13 and 5 ml   min(-1)   kg(-1) for NAQ and NAP, respectively.	BDBM493967	83-86	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
22097826-3	2011	Experimental results indicate that the optimal settings for our LIBS-based device are laser pulse energy = 120 mJ x Pulse(-1), delay time of spectrometer = 200 ns, laser focal point be located 3-5 mm underneath the sample surface, rotation speed of sample cell = 2.7 rev x min(-1), a narrow-band filter with center frequency of 1 064 nm and a diaphragm with center hole diameter of 1.5 mm be placed in the path of the laser beam.	libs	64-68	CD59 molecule (CD59 blood group)	Homo sapiens	273-279
22707821-3	2011	The apparent first-order rate constants for the photochemical and thermal degradation of piroxicam have been determined as 2.04-10.01 and 0.86-3.06x10(-3) min(-1), respectively.	Piroxicam	89-98	CD59 molecule (CD59 blood group)	Homo sapiens	155-161
21665888-7	2011	Of interest, we found that HBx up-regulated CD59 by binding with cAMP response element-binding to the promoter region of the CD59 gene using chromatin immunoprecipitation assay.	Cyclic AMP	65-69	CD59 molecule (CD59 blood group)	Homo sapiens	44-48
21665888-7	2011	Of interest, we found that HBx up-regulated CD59 by binding with cAMP response element-binding to the promoter region of the CD59 gene using chromatin immunoprecipitation assay.	Cyclic AMP	65-69	CD59 molecule (CD59 blood group)	Homo sapiens	125-129
21790328-5	2011	Values at peak exercise for Vo(2) at morning and afternoon testing were 3.20 +- 0.49 and 3.24 +- 0.55 L min(-1), respectively, for heart rate 190 +- 11 and 188 +- 15 bpm, and for cardiac output 19.5 +- 2.8 and 19.8 +- 3.5 L min(-1).	vo(2)	28-33	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
21388348-5	2011	Glucose disposal rates were restored to near normal in diabetic subjects after acipimox (6.2 +- 0.8 compared with 4.8 +- 0.6 mg kgffm-1 min-1; P&lt;0.01; control 6.6 +- 0.5 mg kgffm-1 min-1; where ffm, is fat-free mass).	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
21388348-7	2011	ATP turnover rates did not increase during insulin stimulation in any group, but a modest decrease in the diabetes group was prevented by lowering plasma NEFAs (non-esterified fatty acids; 8.4 +- 0.7 compared with 7.1 +- 0.5 mumol g-1 min-1; P&lt;0.05; controls 8.6 +- 0.8 mumol g-1 min-1).	Fatty Acids, Nonesterified	154-159	CD59 molecule (CD59 blood group)	Homo sapiens	235-240
21388348-7	2011	ATP turnover rates did not increase during insulin stimulation in any group, but a modest decrease in the diabetes group was prevented by lowering plasma NEFAs (non-esterified fatty acids; 8.4 +- 0.7 compared with 7.1 +- 0.5 mumol g-1 min-1; P&lt;0.05; controls 8.6 +- 0.8 mumol g-1 min-1).	Fatty Acids, Nonesterified	154-159	CD59 molecule (CD59 blood group)	Homo sapiens	283-288
21521795-2	2011	Hepatic CPF cytochrome P450 desulfuration [CPF to chlorpyrifos-oxon (CPF-oxon)] and dearylation (CPF to 3,5,6-trichloro-2-pyridinol) V(max) values were 0.35 +- 0.21 and 0.73 +- 0.38 nmol   min(-1)   mg microsomal protein (-1) (mean +- S.D.	Chlorpyrifos	8-11	CD59 molecule (CD59 blood group)	Homo sapiens	189-195
21557013-7	2011	ss-cell glucose sensitivity doubled (37 [33] vs 18 [24] mol min-1 m-2 mM-1, p &lt; 0.0001).	Glucose	8-15	CD59 molecule (CD59 blood group)	Homo sapiens	60-65
21412268-9	2011	Adjusted for age, education, gender, race/ethnicity, smoking, serum cholesterol and diabetes mellitus, the participants with standardized eGFR 60 ml min(-1) per 1.73 m(2) had 56.1% more chance to be hypertensive patients than those with normal eGFR (P&lt;0.0001).	Cholesterol	68-79	CD59 molecule (CD59 blood group)	Homo sapiens	149-155
21611730-5	2011	The peak oxygen uptake was 26% higher in the trained than in the untrained muscle (395 vs. 315 ml min(-1) kg(-1), respectively; P&lt;0.01).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	98-104
21611730-7	2011	The difference between the trained and untrained muscles with respect to peak oxygen uptake (80 ml min(-1) kg(-1)) corresponded to a flux through the Krebs cycle of 1.05 mumol min(-1) g(-1), and the corresponding difference in oxoglutarate dehydrogenase activity (at 38 C) was 0.83 mumol min(-1) g(-1).	Oxygen	78-84	CD59 molecule (CD59 blood group)	Homo sapiens	99-105
21611730-7	2011	The difference between the trained and untrained muscles with respect to peak oxygen uptake (80 ml min(-1) kg(-1)) corresponded to a flux through the Krebs cycle of 1.05 mumol min(-1) g(-1), and the corresponding difference in oxoglutarate dehydrogenase activity (at 38 C) was 0.83 mumol min(-1) g(-1).	Oxygen	78-84	CD59 molecule (CD59 blood group)	Homo sapiens	176-182
21611730-7	2011	The difference between the trained and untrained muscles with respect to peak oxygen uptake (80 ml min(-1) kg(-1)) corresponded to a flux through the Krebs cycle of 1.05 mumol min(-1) g(-1), and the corresponding difference in oxoglutarate dehydrogenase activity (at 38 C) was 0.83 mumol min(-1) g(-1).	Oxygen	78-84	CD59 molecule (CD59 blood group)	Homo sapiens	176-182
21675799-2	2011	The turnover frequency of the hydrogenation of acetophenone reaches about 35,000 min(-1) in the best case, affording 1-phenylethanol in &gt;99% ee.	acetophenone	47-59	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
21675799-2	2011	The turnover frequency of the hydrogenation of acetophenone reaches about 35,000 min(-1) in the best case, affording 1-phenylethanol in &gt;99% ee.	methylphenyl carbinol	117-132	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
21592764-5	2011	A 30 mum coating of PLGA containing 33 wt% of the appropriate NO donor (N-diazeniumdiolated dibutylhexanediamine, DBHD/N2O2) can release NO at a physiologically relevant rate &gt; 1 x 10-10mol min-1 cm-2 for at least 7 days without influencing the analytical performance of the glucose/lactate sensors.	n-diazeniumdiolated dibutylhexanediamine	72-112	CD59 molecule (CD59 blood group)	Homo sapiens	193-198
21642759-5	2011	The particles of n-HAP grow gradually and tend to become spherical-like from the initial needle-like shape, but still maintain a nanoscale structure at scanning speeds between 200 and 300 mm min(-1) when the laser power is 50 W, the light spot diameter 4 mm, and the layer thickness 0.3 mm.	N-hydroxy-2-aminopyrene	17-22	CD59 molecule (CD59 blood group)	Homo sapiens	191-197
21354683-11	2011	Compared with participants with bicarbonate levels &gt;=23 mEq/L, those with bicarbonate levels &lt;23 mEq/L had higher body mass index and serum albumin levels; were more likely to have low socioeconomic status, a diagnosis of diabetes mellitus, or glomerular filtration rate &lt;60 mL/min/1.73 m(2); and were less likely to use diuretics.	Bicarbonates	77-88	CD59 molecule (CD59 blood group)	Homo sapiens	287-292
21536847-7	2011	POTS subjects had an increased peripheral chemoreflex sensitivity (in l min(-1) %oxygen(-1)) in response to hypoxia (0.42 +- 0.38 vs. 0.19 +- 0.17) but a decreased central chemoreflex sensitivity (l min(-1) Torr(-1)) CO(2) response (0.49 +- 0.38 vs. 1.04 +- 0.18) compared with controls.	Oxygen	81-87	CD59 molecule (CD59 blood group)	Homo sapiens	72-78
21399490-4	2011	Analgesia was provided by remifentanil (0.25 mug   kg-1   min-1).	Remifentanil	26-38	CD59 molecule (CD59 blood group)	Homo sapiens	58-63
21742628-4	2011	For the determination of naphthalene, the diffusive sampling rate was 0.41 ml min(-1) with a coefficient of variation (CV) of 19%.	naphthalene	25-36	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
21742628-5	2011	The mean sampling rate for phenanthrene was 0.49 ml min(-1) with a CV of 21%.	phenanthrene	27-39	CD59 molecule (CD59 blood group)	Homo sapiens	52-58
21784373-8	2011	CONCLUSIONS AND IMPLICATIONS: These data confirm that niacin"s phosphorus-lowering effects-which may have therapeutic implications for the management of hyperphosphatemia and possible prevention of cardiorenal outcomes in renal disease-extend across a broad spectrum of renal function in type 2 diabetics without stage 4 or 5 chronic kidney disease (a glomerular filtration rate &gt;=30 mL/min/1.73 m(2)).	Niacin	54-60	CD59 molecule (CD59 blood group)	Homo sapiens	390-395
21646714-9	2011	The global O(2) uptake measured by EIT was 208 +- 79 ml min(-1) corresponding to the values obtained by metabolic gas exchange (259 +- 73 ml min(-1); Spearman correlation coefficient: 0.81, p = 0.02).	Oxygen	11-15	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
21646714-9	2011	The global O(2) uptake measured by EIT was 208 +- 79 ml min(-1) corresponding to the values obtained by metabolic gas exchange (259 +- 73 ml min(-1); Spearman correlation coefficient: 0.81, p = 0.02).	Oxygen	11-15	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
21512709-3	2011	As a result, the 0.4 wt% Pt-loaded nanosheets exhibit superior catalytic activity in H(2)O(2) decomposition with an O(2) evolution rate of 342.5 mL g(-1) min(-1) in a clean aqueous system.	Platinum	25-27	CD59 molecule (CD59 blood group)	Homo sapiens	154-160
21402850-9	2011	Daily vancomycin requirements were dependent on CrCl, such that a patient with a CrCl of 100 ml/min/1.73 m2 would require at least 35 mg/kg per day by continuous infusion to maintain target concentrations.	Vancomycin	6-16	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
21446918-5	2011	Heterologous expression of human and rat OAT2 in HEK (human embryonic kidney)-293 cells stimulated accumulation of the zwitterion trigonelline; subsequently, orotic acid was identified as an excellent and specific substrate of OAT2 from the rat (clearance=106 mul min-1 mg of protein-1) and human (46 mul min-1 mg of protein-1).	Orotic Acid	158-169	CD59 molecule (CD59 blood group)	Homo sapiens	264-269
21446918-5	2011	Heterologous expression of human and rat OAT2 in HEK (human embryonic kidney)-293 cells stimulated accumulation of the zwitterion trigonelline; subsequently, orotic acid was identified as an excellent and specific substrate of OAT2 from the rat (clearance=106 mul min-1 mg of protein-1) and human (46 mul min-1 mg of protein-1).	Orotic Acid	158-169	CD59 molecule (CD59 blood group)	Homo sapiens	305-310
21386720-6	2011	Recovery HR (RecHR) (15 minutes postexercise) was significantly higher for GB (91 +- 14 b   min(-1)) than for DDR (80 +- 11 b   min(-1)) and neared significance vs. CE (84 +- 14 b   min(-1), p = 0.059).	gb	75-77	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
21710767-7	2011	Twenty minutes after starting dantrolene infusion, these values decreased to 38 degrees C, 150 beats x min(-1), and 39 mmHg, respectively.	Dantrolene	30-40	CD59 molecule (CD59 blood group)	Homo sapiens	103-109
21420239-2	2011	Sample solutions were passed through a column at pH 4.5 then retained mercury ions on the column were eluted with minimal amount of 0.01 M nitric acid with 3 mL min(-1) flow rate.	Mercury	70-77	CD59 molecule (CD59 blood group)	Homo sapiens	161-167
21519315-7	2011	RESULTS: GFR slope (-5.85 vs. -3.21 mL/min/1.73 m per year) and graft failure rate (29% vs. 9%, P=0.039) were worse in patients with DSA.	dsa	133-136	CD59 molecule (CD59 blood group)	Homo sapiens	39-44
21360149-7	2011	Finally, with the optimal flow rate of 10 ml min(-1) and loading amount of 80 ml, the yield of 1,3-propanediol achieved was 89%.	1,3-propanediol	95-110	CD59 molecule (CD59 blood group)	Homo sapiens	45-51
21543028-9	2011	Oral iron supplementation was effective, especially in patients with eGFR &lt; 30 ml/min/1.73 m2.	Iron	5-9	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
21262347-6	2011	We found that PpIX was a potent competitive inhibitor of TrxR1, with a K(i)=2.7 muM with regard to Trx1, and in the absence of Trx1 displayed time-dependent irreversible inhibition with an apparent second-order rate constant (k(inact)) of (0.73 +- 0.07) x 10-3 muM-1 min-1.	protoporphyrin IX	14-18	CD59 molecule (CD59 blood group)	Homo sapiens	267-272
21609293-5	2011	Glucose and GP were oxidized on average at 0.54 g min(-1) (coefficient of variation (CV) 37%) and 0.41 g min(-1) (CV 60%), respectively, which equated to a moderate (effect size) reduction of 24% (90% confidence limits: +-22%) with GP.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	50-56
21609293-5	2011	Glucose and GP were oxidized on average at 0.54 g min(-1) (coefficient of variation (CV) 37%) and 0.41 g min(-1) (CV 60%), respectively, which equated to a moderate (effect size) reduction of 24% (90% confidence limits: +-22%) with GP.	Glucose	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
21609293-6	2011	The endogenous carbohydrate oxidation rate with glucose (1.04 g min(-1); CV 68%) was not clearly different from GP (15%; 90% confidence limits: +-24%) and total carbohydrate oxidation rate was not affected.	Carbohydrates	15-27	CD59 molecule (CD59 blood group)	Homo sapiens	64-70
21485403-4	2011	RESULTS: CO(reb) rose from 5.03 +/- 0.7 upright ground control to 11.45 +/- 3.6 L x min(-1) in 0 Gz.	co(reb)	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
21435929-8	2011	Renal complications were not monitored carefully enough (missing value for albuminuria: 42%; -4.5 points), and 46% of those with a glomerular filtration rate less than 60 mL/min/1.73 m2 were taking metformin.	Metformin	198-207	CD59 molecule (CD59 blood group)	Homo sapiens	174-179
21119518-4	2011	The fresh gas flow rate was 1 l min(-1) (0.5 l min(-1) O2 + 0.5 l min(-1) N2O + desflurane) in group 1 and 3 l min(-1) (1.5 l min(-1) O2 + 1.5 l min(-1) N2O + desflurane) in group 2.	Oxygen	55-57	CD59 molecule (CD59 blood group)	Homo sapiens	47-53
21119518-4	2011	The fresh gas flow rate was 1 l min(-1) (0.5 l min(-1) O2 + 0.5 l min(-1) N2O + desflurane) in group 1 and 3 l min(-1) (1.5 l min(-1) O2 + 1.5 l min(-1) N2O + desflurane) in group 2.	Oxygen	55-57	CD59 molecule (CD59 blood group)	Homo sapiens	47-53
21119518-4	2011	The fresh gas flow rate was 1 l min(-1) (0.5 l min(-1) O2 + 0.5 l min(-1) N2O + desflurane) in group 1 and 3 l min(-1) (1.5 l min(-1) O2 + 1.5 l min(-1) N2O + desflurane) in group 2.	Oxygen	55-57	CD59 molecule (CD59 blood group)	Homo sapiens	47-53
21119518-4	2011	The fresh gas flow rate was 1 l min(-1) (0.5 l min(-1) O2 + 0.5 l min(-1) N2O + desflurane) in group 1 and 3 l min(-1) (1.5 l min(-1) O2 + 1.5 l min(-1) N2O + desflurane) in group 2.	Oxygen	55-57	CD59 molecule (CD59 blood group)	Homo sapiens	47-53
21119518-4	2011	The fresh gas flow rate was 1 l min(-1) (0.5 l min(-1) O2 + 0.5 l min(-1) N2O + desflurane) in group 1 and 3 l min(-1) (1.5 l min(-1) O2 + 1.5 l min(-1) N2O + desflurane) in group 2.	Oxygen	55-57	CD59 molecule (CD59 blood group)	Homo sapiens	47-53
21232972-3	2011	Oxygen flow of 5-10 l min(-1) administered by a paediatric intra-field catheter placed in the distal bronchi during bronchial anastomosis of the spared lobe(s), following the principles of apnoeic (hyper)oxygenated ventilation, successfully improves oxygenation without significant impairment of the operation field.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	22-28
20826745-10	2011	Thus, prevalence of CKD with GFR((cys)) &lt; 90 mL/min/1.73 m2; was 30.4%, 7.6% and 27% in patients with 5, 10 and &gt; 10 years of follow-up, respectively.	Cysteine	34-37	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
21344943-2	2011	Heating for 30 min at 545 +- 25  C in argon at a flow rate of 1 L min(-1) removes covalently bound thin organic films, attached via electrografting from aryldiazonium salt solutions.	Argon	38-43	CD59 molecule (CD59 blood group)	Homo sapiens	66-72
21344943-2	2011	Heating for 30 min at 545 +- 25  C in argon at a flow rate of 1 L min(-1) removes covalently bound thin organic films, attached via electrografting from aryldiazonium salt solutions.	aryldiazonium salt	153-171	CD59 molecule (CD59 blood group)	Homo sapiens	66-72
21299210-4	2011	The pumping of water is efficient: 13 000 water molecules are pumped per reacted electron and 4.8 mL of water are pumped per joule at a flow rate of 0.13 mL min(-1) V(-1) cm(-2), and a flow rate per unit of power is 290 mL min(-1) W(-1).	Water	15-20	CD59 molecule (CD59 blood group)	Homo sapiens	157-163
21299210-4	2011	The pumping of water is efficient: 13 000 water molecules are pumped per reacted electron and 4.8 mL of water are pumped per joule at a flow rate of 0.13 mL min(-1) V(-1) cm(-2), and a flow rate per unit of power is 290 mL min(-1) W(-1).	Water	15-20	CD59 molecule (CD59 blood group)	Homo sapiens	223-229
21193565-8	2011	During propranolol alone, the rise in FVC (Delta from normoxic baseline) due to hypoxic exercise was 217 +- 29 and 415 +- 41 ml min(-1) 100 mmHg(-1) (10% and 20% of maximum, respectively).	Propranolol	7-18	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
21193565-9	2011	Combined propranolol-l-NMMA infusion during hypoxic exercise attenuated DeltaFVC at 20% (352 +- 44 ml min(-1) 100 mmHg(-1); P &lt; 0.001) but not at 10% (202 +- 28 ml min(-1) 100 mmHg(-1); P = 0.08) of maximum compared with propranolol alone.	propranolol-l-nmma	9-27	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
21193565-9	2011	Combined propranolol-l-NMMA infusion during hypoxic exercise attenuated DeltaFVC at 20% (352 +- 44 ml min(-1) 100 mmHg(-1); P &lt; 0.001) but not at 10% (202 +- 28 ml min(-1) 100 mmHg(-1); P = 0.08) of maximum compared with propranolol alone.	propranolol-l-nmma	9-27	CD59 molecule (CD59 blood group)	Homo sapiens	167-173
21193565-9	2011	Combined propranolol-l-NMMA infusion during hypoxic exercise attenuated DeltaFVC at 20% (352 +- 44 ml min(-1) 100 mmHg(-1); P &lt; 0.001) but not at 10% (202 +- 28 ml min(-1) 100 mmHg(-1); P = 0.08) of maximum compared with propranolol alone.	Propranolol	9-20	CD59 molecule (CD59 blood group)	Homo sapiens	102-108
21193565-9	2011	Combined propranolol-l-NMMA infusion during hypoxic exercise attenuated DeltaFVC at 20% (352 +- 44 ml min(-1) 100 mmHg(-1); P &lt; 0.001) but not at 10% (202 +- 28 ml min(-1) 100 mmHg(-1); P = 0.08) of maximum compared with propranolol alone.	Propranolol	9-20	CD59 molecule (CD59 blood group)	Homo sapiens	167-173
21152606-8	2011	Carbon dioxide transfer within the device was 156 ml min(-1) m(-2) and the oxygen transfer was 34 ml min(-1) m(-2).	Carbon Dioxide	0-14	CD59 molecule (CD59 blood group)	Homo sapiens	53-59
20848646-5	2011	The numerical model adequately predicts the ibuprofen particle dissolution rate at 16 mL min(-1) .	Ibuprofen	44-53	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
20580255-3	2011	The baseline eGFR in the edaravone-treated group (73.5+-20.3 mL/min/1.73 m(2); n=408) at admission was significantly (P &lt; .05) higher than that in the non-edaravone-treated group (51.9+-25.2 mL/min/1.73 m(2); n=41).	Edaravone	25-34	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
20580255-3	2011	The baseline eGFR in the edaravone-treated group (73.5+-20.3 mL/min/1.73 m(2); n=408) at admission was significantly (P &lt; .05) higher than that in the non-edaravone-treated group (51.9+-25.2 mL/min/1.73 m(2); n=41).	Edaravone	25-34	CD59 molecule (CD59 blood group)	Homo sapiens	197-202
20580255-6	2011	We next subdivided the edaravone-treated group according to eGFR at admission as either CKD (eGFR &lt;60 mL/min/1.73 m(2); n=111) and non-CKD (n=297).	Edaravone	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
21152606-8	2011	Carbon dioxide transfer within the device was 156 ml min(-1) m(-2) and the oxygen transfer was 34 ml min(-1) m(-2).	Oxygen	75-81	CD59 molecule (CD59 blood group)	Homo sapiens	101-107
21238752-8	2011	A mobile phase of acetonitrile and triethylamine (25 mM) at pH 2.5, through a gradient of composition at a flow rate of 20 muL min(-1), resulted in good separations between the analytes in less than 11 min.	acetonitrile	18-30	CD59 molecule (CD59 blood group)	Homo sapiens	127-133
21238752-8	2011	A mobile phase of acetonitrile and triethylamine (25 mM) at pH 2.5, through a gradient of composition at a flow rate of 20 muL min(-1), resulted in good separations between the analytes in less than 11 min.	triethylamine	35-48	CD59 molecule (CD59 blood group)	Homo sapiens	127-133
21225886-5	2011	However, the CD59 mutation frequency and the cell cycle distribution were not significantly affected by exposure to 8.5 T SMF for 3 h. Our results indicated that the cellular ATP content was reduced by 8.5 T SMF for 3 h exposure, which was partially mediated by mitochondria and the DNA DSB repair process.	Adenosine Triphosphate	175-178	CD59 molecule (CD59 blood group)	Homo sapiens	13-17
21183681-8	2011	The increased cellular levels of Dol-P-Man and possibly the decreased cholesterol levels in zaragozic acid A-treated cells also led to increased availability of the glycosylphosphatidylinositol anchor as shown by the elevated cell-surface expression of the CD59 protein.	squalestatin 1	92-108	CD59 molecule (CD59 blood group)	Homo sapiens	257-261
21183681-8	2011	The increased cellular levels of Dol-P-Man and possibly the decreased cholesterol levels in zaragozic acid A-treated cells also led to increased availability of the glycosylphosphatidylinositol anchor as shown by the elevated cell-surface expression of the CD59 protein.	Glycosylphosphatidylinositols	165-193	CD59 molecule (CD59 blood group)	Homo sapiens	257-261
21118844-8	2011	RESULTS: HR, K-ICG, and BIS were significantly decreased in the remifentanil 0 microg kg-1 min-1 group.	Remifentanil	64-76	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
21118844-9	2011	The decrease in MAP, HR, CI, and K-ICG was significantly lower in the remifentanil 0.5 and 1.0 microg kg-1 min-1 groups compared with the remifentanil 0 microg kg-1 min-1 group.	Remifentanil	70-82	CD59 molecule (CD59 blood group)	Homo sapiens	165-170
21219402-7	2011	Gentamicin clearance was significantly lower in frail participants (46.6 +- 10.7 ml min(-1)) than in non frail (58.2 +- 12.4 ml min(-1), P=0.01).	Gentamicins	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
21219402-7	2011	Gentamicin clearance was significantly lower in frail participants (46.6 +- 10.7 ml min(-1)) than in non frail (58.2 +- 12.4 ml min(-1), P=0.01).	Gentamicins	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
21112594-6	2011	They ranged from 0.026 cm2 min-1 for 1,1-dichloroethylene to 0.605 cm2 min-1 for n-octanol.	vinylidene chloride	37-57	CD59 molecule (CD59 blood group)	Homo sapiens	27-32
21219402-8	2011	The Cockcroft Gault estimate of creatinine clearance calculated using ideal bodyweight gave the best estimate of gentamicin clearance (mean error -0.15 ml min(-1), 95% CI -2.67, 2.39).	Creatinine	32-42	CD59 molecule (CD59 blood group)	Homo sapiens	155-161
21219402-8	2011	The Cockcroft Gault estimate of creatinine clearance calculated using ideal bodyweight gave the best estimate of gentamicin clearance (mean error -0.15 ml min(-1), 95% CI -2.67, 2.39).	Gentamicins	113-123	CD59 molecule (CD59 blood group)	Homo sapiens	155-161
21255540-15	2011	For the AVA group, the mean delta eGFR was lower after the Z-point compared to before (-0.63 vs. -0.21 ml/min/1.73 m2, p=0.002).	avenic acid A	8-11	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
21315037-1	2011	AIM: To study the enhancement effect of glycosylphosphatidyl inositol (GPI)-anchored protein CD59 on CD55-mediated T cell signal transduction.	Glycosylphosphatidylinositols	40-69	CD59 molecule (CD59 blood group)	Homo sapiens	93-97
21315037-1	2011	AIM: To study the enhancement effect of glycosylphosphatidyl inositol (GPI)-anchored protein CD59 on CD55-mediated T cell signal transduction.	Glycosylphosphatidylinositols	71-74	CD59 molecule (CD59 blood group)	Homo sapiens	93-97
21112594-6	2011	They ranged from 0.026 cm2 min-1 for 1,1-dichloroethylene to 0.605 cm2 min-1 for n-octanol.	1-Octanol	81-90	CD59 molecule (CD59 blood group)	Homo sapiens	71-76
20680288-8	2011	CONCLUSION: The use of iodixanol appears to be safe in patients with monoclonal gammopathies and an eGFR&gt;= 60 ml/min/1.73 mq.	iodixanol	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	116-121
21304220-2	2011	METHODS: The PDC activator, dichloroacetate (DCA), was administered as an intravenous infusion in healthy male subjects at a rate of 50 mg kg(-1) min(-1), for 90 min.	Dichloroacetic Acid	28-43	CD59 molecule (CD59 blood group)	Homo sapiens	146-152
21304220-8	2011	Carbohydrate oxidation was increased by DCA, 0.037 +- 0.017 g min(-1) (p &lt; 0.05) at 3 h with no change observed in CON.	Carbohydrates	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
21304220-8	2011	Carbohydrate oxidation was increased by DCA, 0.037 +- 0.017 g min(-1) (p &lt; 0.05) at 3 h with no change observed in CON.	Dichloroacetic Acid	40-43	CD59 molecule (CD59 blood group)	Homo sapiens	62-68
20961375-7	2011	It is of interest that sustained PKC activation leads to a similar coalescence of CD59 at the ERC, and treatment of EHD1-depleted cells with a PKC inhibitor (Go6976) blocked this rapid relocation of CD59.	Go 6976	158-164	CD59 molecule (CD59 blood group)	Homo sapiens	82-86
20961375-7	2011	It is of interest that sustained PKC activation leads to a similar coalescence of CD59 at the ERC, and treatment of EHD1-depleted cells with a PKC inhibitor (Go6976) blocked this rapid relocation of CD59.	Go 6976	158-164	CD59 molecule (CD59 blood group)	Homo sapiens	199-203
20959938-4	2010	The polydimethylsiloxane (PDMS) nanopump design is able to produce intermittent delivery or removal of several nanolitres of fluid per revolution as well as consistent continuous flow rates ranging from as low as 15 nL min(-1) to above 1.0 microL min(-1).	baysilon	4-24	CD59 molecule (CD59 blood group)	Homo sapiens	219-225
21117280-4	2010	EXPERIMENTAL APPROACH: Seven pregnant ewes received a continuous infusion of remifentanil (0.33 microg kg-1 min-1) for 1 h, and maternal and fetal arterial blood samples were drawn at regular intervals during and up to 1 h after the discontinuation of the infusion.	Remifentanil	77-89	CD59 molecule (CD59 blood group)	Homo sapiens	108-122
20977579-7	2010	RESULTS: At the University of Chicago Diabetes Center, 36 of 234 (15.3%) patients with an eGFR of &lt;60 ml/min/1.73 m(2) were receiving metformin.	Metformin	137-146	CD59 molecule (CD59 blood group)	Homo sapiens	108-113
20977579-8	2010	Data from NHANES, age &gt;18 years and eGFR &lt;60 ml/min/1.73 m(2) showed that Blacks with advanced nephropathy were three times more likely to receive metformin.	Metformin	153-162	CD59 molecule (CD59 blood group)	Homo sapiens	54-59
20977579-9	2010	CONCLUSIONS: We conclude that metformin utilization occurs with a higher frequency than predicted by serum creatinine in people with eGFR &lt;60 ml/min/1.73 m(2) .	Metformin	30-39	CD59 molecule (CD59 blood group)	Homo sapiens	148-153
20848080-9	2010	The mean remifentanil dose administered was 0.07 +- 0.03 mug kg(-1) min(-1).	Remifentanil	9-21	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
24149782-7	2010	The lactate threshold was higher than ventilatory one both in obese and normal weight women (1.11 +- 0.21 vs 0.88 +- 0.18 L min(-1), p &lt; 0.001; 0.94 +- 0.15 vs 0.79 +- 0.23 L min(- 1), p &lt; 0.01, respectively).	Lactic Acid	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	124-130
24149782-7	2010	The lactate threshold was higher than ventilatory one both in obese and normal weight women (1.11 +- 0.21 vs 0.88 +- 0.18 L min(-1), p &lt; 0.001; 0.94 +- 0.15 vs 0.79 +- 0.23 L min(- 1), p &lt; 0.01, respectively).	Lactic Acid	4-11	CD59 molecule (CD59 blood group)	Homo sapiens	178-185
21215189-8	2010	And then, the effects of P38MAPK, PI-3K and ERK1/2 pathway inhibitors (SB203580, LY294002, U0126) and DMSO on CD59 and Crry expression were respectively detected by flow cytometry.	SB 203580	71-79	CD59 molecule (CD59 blood group)	Homo sapiens	110-114
21215189-8	2010	And then, the effects of P38MAPK, PI-3K and ERK1/2 pathway inhibitors (SB203580, LY294002, U0126) and DMSO on CD59 and Crry expression were respectively detected by flow cytometry.	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	81-89	CD59 molecule (CD59 blood group)	Homo sapiens	110-114
20944849-1	2010	Vapor deposited thin films (~100 nm thickness) of toluene and ethylbenzene grown by physical vapor deposition show enhanced stability with respect to samples slowly cooled from the liquid at a rate of 5 K min(-1).	Toluene	50-57	CD59 molecule (CD59 blood group)	Homo sapiens	205-211
20944849-1	2010	Vapor deposited thin films (~100 nm thickness) of toluene and ethylbenzene grown by physical vapor deposition show enhanced stability with respect to samples slowly cooled from the liquid at a rate of 5 K min(-1).	ethylbenzene	62-74	CD59 molecule (CD59 blood group)	Homo sapiens	205-211
20959938-4	2010	The polydimethylsiloxane (PDMS) nanopump design is able to produce intermittent delivery or removal of several nanolitres of fluid per revolution as well as consistent continuous flow rates ranging from as low as 15 nL min(-1) to above 1.0 microL min(-1).	baysilon	4-24	CD59 molecule (CD59 blood group)	Homo sapiens	247-253
20959938-4	2010	The polydimethylsiloxane (PDMS) nanopump design is able to produce intermittent delivery or removal of several nanolitres of fluid per revolution as well as consistent continuous flow rates ranging from as low as 15 nL min(-1) to above 1.0 microL min(-1).	baysilon	26-30	CD59 molecule (CD59 blood group)	Homo sapiens	219-225
20959938-4	2010	The polydimethylsiloxane (PDMS) nanopump design is able to produce intermittent delivery or removal of several nanolitres of fluid per revolution as well as consistent continuous flow rates ranging from as low as 15 nL min(-1) to above 1.0 microL min(-1).	baysilon	26-30	CD59 molecule (CD59 blood group)	Homo sapiens	247-253
20826630-6	2010	RESULTS: In GLUFRU, lactate appearance (120 +- 6 mumol   kg-1   min-1), lactate disappearance (121 +- 7 mumol   kg-1   min-1), and oxidation (127 +- 12 mumol   kg-1   min-1) rates increased significantly (P &lt; 0.001) in comparison with glucose alone (94 +- 16, 95 +- 16, and 97 +- 16 mumol   kg-1   min-1, respectively).	Lactic Acid	20-27	CD59 molecule (CD59 blood group)	Homo sapiens	64-69
20826630-8	2010	In GLUFRU, GNG(F) and exogenous fructose oxidation increased with time and leveled off at 18.8 +- 3.7 and 38 +- 4 mumol   kg-1   min-1, respectively, at 100 min.	Fructose	32-40	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
20826630-9	2010	Plasma glucose appearance rate was significantly higher (P &lt; 0.01) in GLUFRU (91 +- 6 mumol   kg-1   min-1) than in glucose alone (82 +- 9 mumol   kg-1   min-1).	Glucose	7-14	CD59 molecule (CD59 blood group)	Homo sapiens	104-109
20826630-9	2010	Plasma glucose appearance rate was significantly higher (P &lt; 0.01) in GLUFRU (91 +- 6 mumol   kg-1   min-1) than in glucose alone (82 +- 9 mumol   kg-1   min-1).	Glucose	7-14	CD59 molecule (CD59 blood group)	Homo sapiens	157-162
20618356-3	2010	infusion of adrenaline (0.1 nmol kg-1 min-1) or placebo.	Epinephrine	12-22	CD59 molecule (CD59 blood group)	Homo sapiens	38-43
20404762-7	2010	RESULTS: During the final 2 h of exercise, overall mean exogenous CHO oxidation rate was -0.11 g min-1 lower in BAR (95% confidence interval = -0.27 to 0.05 g min-1, P = 0.19) relative to DRINK, whereas exogenous CHO oxidation rates were 15% lower in BAR (P &lt; 0.05) at 120, 135, and 150 min of exercise.	CAV protocol	66-69	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
20404762-8	2010	Peak exogenous CHO oxidation rates were high in both conditions (BAR 1.25 +- 0.15 g min-1 and DRINK 1.34 +- 0.27 g min-1) but were not significantly different (P = 0.36) between treatments (mean difference = -0.9 g min-1, 95% confidence interval = -0.32 to 0.13 g min-1).	CAV protocol	15-18	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
20404762-8	2010	Peak exogenous CHO oxidation rates were high in both conditions (BAR 1.25 +- 0.15 g min-1 and DRINK 1.34 +- 0.27 g min-1) but were not significantly different (P = 0.36) between treatments (mean difference = -0.9 g min-1, 95% confidence interval = -0.32 to 0.13 g min-1).	CAV protocol	15-18	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
20404762-8	2010	Peak exogenous CHO oxidation rates were high in both conditions (BAR 1.25 +- 0.15 g min-1 and DRINK 1.34 +- 0.27 g min-1) but were not significantly different (P = 0.36) between treatments (mean difference = -0.9 g min-1, 95% confidence interval = -0.32 to 0.13 g min-1).	CAV protocol	15-18	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
20404762-8	2010	Peak exogenous CHO oxidation rates were high in both conditions (BAR 1.25 +- 0.15 g min-1 and DRINK 1.34 +- 0.27 g min-1) but were not significantly different (P = 0.36) between treatments (mean difference = -0.9 g min-1, 95% confidence interval = -0.32 to 0.13 g min-1).	CAV protocol	15-18	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
20404762-9	2010	CONCLUSIONS: The present study demonstrates that a GLU + FRC mix administered as a solid BAR during cycling can lead to high mean and peak exogenous CHO oxidation rates (91 g min-1).	CAV protocol	149-152	CD59 molecule (CD59 blood group)	Homo sapiens	175-180
20404763-7	2010	Both CHO treatments delivered GLU plus FRC in a ratio of 2:1 at a rate of 1.8 g min-1 (108 g h-1).	CAV protocol	5-8	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
20404763-7	2010	Both CHO treatments delivered GLU plus FRC in a ratio of 2:1 at a rate of 1.8 g min-1 (108 g h-1).	Glucose	30-33	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
21355274-3	2010	The flow rate was 1 mL x min(-1), the detection wavelength was 360 nm; and the column temperature was set at 25 degrees C. RESULT: The linear ranges of quercetin and kaempferol are 0.22-1.1 microg and 0.42-2.1 microg.	Quercetin	152-161	CD59 molecule (CD59 blood group)	Homo sapiens	25-31
20693291-5	2010	Infusion of PE and BHT-933 resulted in greater absolute decreases in FVC during leg heating compared to normothermic conditions (maximal decreases in FVC during heating vs. normothermia: PE: 7.8 +- 1.1 vs. 2.8 +- 0.5 ml min-1 mmHg-1; BHT-933: 8.6 +- 1.7 vs. 2.1 +- 0.4 ml min-1 mmHg-1; P &lt; 0.01 for both).	Phenylephrine	12-14	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
20693291-5	2010	Infusion of PE and BHT-933 resulted in greater absolute decreases in FVC during leg heating compared to normothermic conditions (maximal decreases in FVC during heating vs. normothermia: PE: 7.8 +- 1.1 vs. 2.8 +- 0.5 ml min-1 mmHg-1; BHT-933: 8.6 +- 1.7 vs. 2.1 +- 0.4 ml min-1 mmHg-1; P &lt; 0.01 for both).	Phenylephrine	12-14	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
20693291-5	2010	Infusion of PE and BHT-933 resulted in greater absolute decreases in FVC during leg heating compared to normothermic conditions (maximal decreases in FVC during heating vs. normothermia: PE: 7.8 +- 1.1 vs. 2.8 +- 0.5 ml min-1 mmHg-1; BHT-933: 8.6 +- 1.7 vs. 2.1 +- 0.4 ml min-1 mmHg-1; P &lt; 0.01 for both).	Butylated Hydroxytoluene	19-22	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
20693291-5	2010	Infusion of PE and BHT-933 resulted in greater absolute decreases in FVC during leg heating compared to normothermic conditions (maximal decreases in FVC during heating vs. normothermia: PE: 7.8 +- 1.1 vs. 2.8 +- 0.5 ml min-1 mmHg-1; BHT-933: 8.6 +- 1.7 vs. 2.1 +- 0.4 ml min-1 mmHg-1; P &lt; 0.01 for both).	Butylated Hydroxytoluene	19-22	CD59 molecule (CD59 blood group)	Homo sapiens	272-277
20885190-4	2010	Oxygen consumption (VO2, ml kg-1 min-1) was measured with steady-state VO2 requirements and responses determined using the mathematical model from the following equation: VO2 (WR) = VO2 (rest) + VO2 (unloading pedaling) + alpha.WR; DeltaVO2(t, WR) = DeltaVO2 (WR) = [1-e[-(t-td)/tO2].	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	33-38
20960893-3	2010	The remifentanil infusion rate was set to maintain the systolic arterial pressure below 150 mmHg and heart rate below 100 beats x min(-1).	Remifentanil	4-16	CD59 molecule (CD59 blood group)	Homo sapiens	130-136
20960893-4	2010	In 2 of 3 cases, intraoperative hemodynamics were controlled by titrated remifentanil infusion with up to 2 and 3 microg x kg(-1) min(-1) in each case, without additional vasoactive agents.	Remifentanil	73-85	CD59 molecule (CD59 blood group)	Homo sapiens	130-136
20954089-3	2010	The drift tube temperature of the ELSD system was set at 115  C and the nitrogen flow rate was 2.8 L min-1.	Nitrogen	72-80	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
21526629-8	2010	Creatinine clearance was significantly lower in subjects compared to controls 98.86 +/- 21.26 mI/min/1.72m2 vs. 108.18 +/- 25.16 mI/min/1.72m2 (p = 0.002).	Creatinine	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	97-102
20860640-5	2010	Warfarin was used in 80 of 116 patients (69%) with a glomerular filtration rate &lt; 60 mL/min/1.73 m(2) and in 140 of 163 patients (86%) with a glomerular filtration rate &gt;= 60 mL/min/1.73 m(2) .	Warfarin	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	91-96
20860640-5	2010	Warfarin was used in 80 of 116 patients (69%) with a glomerular filtration rate &lt; 60 mL/min/1.73 m(2) and in 140 of 163 patients (86%) with a glomerular filtration rate &gt;= 60 mL/min/1.73 m(2) .	Warfarin	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
21129240-4	2010	Expression of CD59 on NB4 cells was determined by flow cytometry before and after treating with all trans retinoic acid (ATRA).	Tretinoin	100-119	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
21129240-4	2010	Expression of CD59 on NB4 cells was determined by flow cytometry before and after treating with all trans retinoic acid (ATRA).	Tretinoin	121-125	CD59 molecule (CD59 blood group)	Homo sapiens	14-18
21105384-5	2010	The gas temperature decreases from 350 to 300 K when argon flow rate increases from 3.0 to 6.5 mL x min(-1).	Argon	53-58	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
19662541-10	2010	We observed that expression of CD46 and CD59 were higher in patients with CR than in group with NR.	Chromium	74-76	CD59 molecule (CD59 blood group)	Homo sapiens	40-44
20857678-6	2010	In the normal dose group, landiolol infusion was started at a rate of 0.125 mg x kg(-1) x min(-1) for 1 min, decreasing it to 0.04 mg x kg(-1) x min(-1) until the time of extubation.	landiolol	26-35	CD59 molecule (CD59 blood group)	Homo sapiens	90-107
20857678-6	2010	In the normal dose group, landiolol infusion was started at a rate of 0.125 mg x kg(-1) x min(-1) for 1 min, decreasing it to 0.04 mg x kg(-1) x min(-1) until the time of extubation.	landiolol	26-35	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
20857678-7	2010	In the low dose group, landiolol infusion was given at a rate of 0.06 mg x kg(-1) x min(-1) for 1 min and then continuously infused at the rate of 0.02 mg x kg(-1) x min(-1) until extubation.	landiolol	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	84-101
20857678-7	2010	In the low dose group, landiolol infusion was given at a rate of 0.06 mg x kg(-1) x min(-1) for 1 min and then continuously infused at the rate of 0.02 mg x kg(-1) x min(-1) until extubation.	landiolol	23-32	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
20651199-9	2010	At the lower boundary of the 95% CI for sensitivity, the savings incurred would come at the expense of administering gadolinium to 0.4% of patients with an eGFR less than 30 mL/min/1.73 m(2).	Gadolinium	117-127	CD59 molecule (CD59 blood group)	Homo sapiens	177-182
20865877-2	2010	Seventy children were randomly allocated to two groups to receive remifentanil infusion at 0.2 microg x kg(-1) x min(-1) with either sevoflurane or propofol supplements for insertion of the rigid bronchoscope.	Remifentanil	66-78	CD59 molecule (CD59 blood group)	Homo sapiens	113-119
20832702-5	2010	RESULTS: The mean oxygen flow was 1.75 +- 1.58 L x min(-1) (mean +- SD) with a total yield of 40.4 +- 2.6 L. Oxygen flow increased slowly and with substantial variability between reactant groups, exceeding 2.0 L x min(-1) after 15.7 +- 6.4 minutes of operation.	Oxygen	18-24	CD59 molecule (CD59 blood group)	Homo sapiens	51-57
20832702-5	2010	RESULTS: The mean oxygen flow was 1.75 +- 1.58 L x min(-1) (mean +- SD) with a total yield of 40.4 +- 2.6 L. Oxygen flow increased slowly and with substantial variability between reactant groups, exceeding 2.0 L x min(-1) after 15.7 +- 6.4 minutes of operation.	Oxygen	109-115	CD59 molecule (CD59 blood group)	Homo sapiens	51-57
20832702-5	2010	RESULTS: The mean oxygen flow was 1.75 +- 1.58 L x min(-1) (mean +- SD) with a total yield of 40.4 +- 2.6 L. Oxygen flow increased slowly and with substantial variability between reactant groups, exceeding 2.0 L x min(-1) after 15.7 +- 6.4 minutes of operation.	Oxygen	109-115	CD59 molecule (CD59 blood group)	Homo sapiens	214-220
20832702-6	2010	Oxygen flow briefly peaked at 5.93 +- 0.56 L x min(-1) at 17.8 +- 7.9 minutes before rapidly falling to zero.	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	47-53
20575535-1	2010	A novel instrument is described that quantifies total particle-phase organic nitrates in real time with a detection limit of 0.11 microg m(-3) min(-1), 45 ppt min(-1) (-ONO(2)).	Nitrates	77-85	CD59 molecule (CD59 blood group)	Homo sapiens	143-149
20617825-8	2010	With the use of this microfluidic system, a total flow rate of 1.5 +/- 0.1 microL min(-1) was generated and used to deliver sinusoidal waves of glucose concentration with a median value of 11 mM and amplitude of 1 mM to a chamber that contained an islet of Langerhans loaded with the Ca(2+)-sensitive fluorophore, indo-1.	Glucose	144-151	CD59 molecule (CD59 blood group)	Homo sapiens	82-88
20715524-5	2010	RESULTS: Average infusion rate of remifentanil was 0.24 +/- 0.02 microg x kg(-1) x min(-1) and total infused dose of fentanyl was 0.27 +/- 0.05 mg. Average bispectral index values in both groups were comparable.	Remifentanil	34-46	CD59 molecule (CD59 blood group)	Homo sapiens	83-89
20575535-1	2010	A novel instrument is described that quantifies total particle-phase organic nitrates in real time with a detection limit of 0.11 microg m(-3) min(-1), 45 ppt min(-1) (-ONO(2)).	Nitrates	77-85	CD59 molecule (CD59 blood group)	Homo sapiens	159-165
20347511-16	2010	There was a nonsignificant decrease in kidney function in patients on alendronate therapy compared with placebo (-1.2 mL/min/1.73 m(2) [95% CI, -4.0 to 1.7]).	Alendronate	70-81	CD59 molecule (CD59 blood group)	Homo sapiens	121-126
20153664-9	2010	The diffusion capacity of the lung for carbon monoxide (DLCO) also increased (1.25 + or - 4.68 ml min(-1) mmHg(-1)), although not significantly (P = 0.20).	Carbon Monoxide	39-54	CD59 molecule (CD59 blood group)	Homo sapiens	98-104
20203244-7	2010	On Day 17 versus Day 14, after fluticasone, inspiratory flow increased (45 L x min(-1); 30-61; P &lt; 0.001) and the DRC shifted upward (26.2 L x min(-1); 21.7-30.7; P &lt; 0.001).	Fluticasone	31-42	CD59 molecule (CD59 blood group)	Homo sapiens	79-85
20203244-8	2010	On Day 1, prazosin reduced inspiratory flow (-52.6 L x min(-1); -19.2 to -86) compared with baseline.	Prazosin	10-18	CD59 molecule (CD59 blood group)	Homo sapiens	55-61
20689133-6	2010	Mean fluorescence level of CD(59) (+) mature erythrocytes was lowest in the PNH subjects (24.5 x 10(3) MESF), significantly less than in normal controls (39.0 x 10(3) MESF, p &lt;0.05), and highest in the AA subjects (49.2 x 10(3) MESF).	mesf	103-107	CD59 molecule (CD59 blood group)	Homo sapiens	27-33
20689133-6	2010	Mean fluorescence level of CD(59) (+) mature erythrocytes was lowest in the PNH subjects (24.5 x 10(3) MESF), significantly less than in normal controls (39.0 x 10(3) MESF, p &lt;0.05), and highest in the AA subjects (49.2 x 10(3) MESF).	mesf	167-171	CD59 molecule (CD59 blood group)	Homo sapiens	27-33
20689133-6	2010	Mean fluorescence level of CD(59) (+) mature erythrocytes was lowest in the PNH subjects (24.5 x 10(3) MESF), significantly less than in normal controls (39.0 x 10(3) MESF, p &lt;0.05), and highest in the AA subjects (49.2 x 10(3) MESF).	mesf	167-171	CD59 molecule (CD59 blood group)	Homo sapiens	27-33
20436356-10	2010	Peak oxygen uptake increased from pre-LVAD measures of 11.8 mL x kg(-1) x min(-1) to 17.0 mL x kg(-1) x min(-1).	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	74-80
20436356-10	2010	Peak oxygen uptake increased from pre-LVAD measures of 11.8 mL x kg(-1) x min(-1) to 17.0 mL x kg(-1) x min(-1).	Oxygen	5-11	CD59 molecule (CD59 blood group)	Homo sapiens	104-110
20939292-3	2010	Cinnamic acid was determined by LC-MS-MS using a ZOBAX SB C18 column with a mobile phase of methanol-water (containing 2 mmol x L(-1) ammonium acetic) (45: 55) at a flow rate of 0.5 mL x min(-1) and detected using ESI with negative ionization mode.	cinnamic acid	0-13	CD59 molecule (CD59 blood group)	Homo sapiens	187-193
20460830-7	2010	A significant increase of the eGFR (+5.4 mL/min/1.73 m(2)) was observed after 104 weeks of pitavastain treatment (p &lt; 0.001; one-sample t-test).	pitavastain	91-102	CD59 molecule (CD59 blood group)	Homo sapiens	44-49
20460830-8	2010	In the analysis of the time-course of changes in the eGFR in response to pitavastatin treatment, the eGFR was elevated by 2.4 mL/min/1.73 m(2) after 12 weeks" treatment, and by 5.6 mL/min/1.73 m(2) after 104 weeks" treatment (p &lt; 0.001; repeated measures ANOVA).	pitavastatin	73-85	CD59 molecule (CD59 blood group)	Homo sapiens	129-134
20460830-8	2010	In the analysis of the time-course of changes in the eGFR in response to pitavastatin treatment, the eGFR was elevated by 2.4 mL/min/1.73 m(2) after 12 weeks" treatment, and by 5.6 mL/min/1.73 m(2) after 104 weeks" treatment (p &lt; 0.001; repeated measures ANOVA).	pitavastatin	73-85	CD59 molecule (CD59 blood group)	Homo sapiens	184-189
20462234-2	2010	The copper deposition rate in the electroless bath was determined to be 50 nm min(-1), through electrochemical stripping of the copper deposits as well as from direct measurements of the film thickness using atomic force microscopy (AFM).	Copper	4-10	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
20421646-4	2010	REST68 inhibited CD59 expression in malignant cells expressing either truncated or full-length REST, but not in nonmalignant cells.	rest68	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	17-21
20421646-6	2010	Combined treatment of different tumor types with REST68 and PKC inhibitor synergized to further suppress CD59 expression and reduce resistance to complement lysis.	rest68	49-55	CD59 molecule (CD59 blood group)	Homo sapiens	105-109
20585293-8	2010	After the tenth week, we found a reduction of 11 beats.min-1 in average training heart rate, an increase of 0.5 mL/kg-1.min-1 in average training oxygen uptake and an increase of 8.6 Watts in average power output.	Oxygen	146-152	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
20427317-7	2010	Density gradient centrifugation revealed co-partitioning of CD59 and p24-p23 into biosynthetically early lipid raft fractions, and CD59 transport to the Golgi was cholesterol dependent.	Cholesterol	163-174	CD59 molecule (CD59 blood group)	Homo sapiens	131-135
20424611-8	2010	A relationship was detected between creatinine clearance &lt;or=50 ml min(-1) and the development of non-bevacizumab-related grade 3/4 AEs.	Creatinine	36-46	CD59 molecule (CD59 blood group)	Homo sapiens	70-76
20339194-4	2010	Landiolol was administered intravenously with an initial dose of 2.5 microg x kg(-1) x min(-1), which was doubled if it was ineffective, up to a maximum dose of 80 microg x kg(-1) x min(-1).	landiolol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
20339194-4	2010	Landiolol was administered intravenously with an initial dose of 2.5 microg x kg(-1) x min(-1), which was doubled if it was ineffective, up to a maximum dose of 80 microg x kg(-1) x min(-1).	landiolol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	182-188
20339194-5	2010	Landiolol inhibited ES in 33 patients (79%) at a mean dose of 7.5+/-12.2 microg x kg(-1) x min(-1).	landiolol	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	91-97
19727797-5	2010	Swilling with menthol resulted in hyperventilation by 8 +/- 10 L min(-1) and reduced central (cardiopulmonary) ratings of perceived exertion by 15 +/- 14%.	Menthol	14-21	CD59 molecule (CD59 blood group)	Homo sapiens	65-71
20435936-9	2010	Propofol (C(blood): 1.2 microg x mL(-1)) reduced midazolam central volume of distribution from 5.37 to 2.98 L, elimination clearance from 0.39 to 0.31 L x min(-1), and rapid distribution clearance from 2.77 to 2.11 L x min(-1).	Propofol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	155-161
20435936-9	2010	Propofol (C(blood): 1.2 microg x mL(-1)) reduced midazolam central volume of distribution from 5.37 to 2.98 L, elimination clearance from 0.39 to 0.31 L x min(-1), and rapid distribution clearance from 2.77 to 2.11 L x min(-1).	Propofol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	219-225
20049481-4	2010	The bias +/-95% limits of agreement (LOA) for VO(2) was 393 +/- 507 ml min(-1) for the submaximal constant work test at 100 W and 495 +/- 727 ml min(-1) for VO(2max).	vo(2)	46-51	CD59 molecule (CD59 blood group)	Homo sapiens	71-77
20049481-4	2010	The bias +/-95% limits of agreement (LOA) for VO(2) was 393 +/- 507 ml min(-1) for the submaximal constant work test at 100 W and 495 +/- 727 ml min(-1) for VO(2max).	vo(2)	46-51	CD59 molecule (CD59 blood group)	Homo sapiens	145-151
20049481-5	2010	At maximal intensity, cardiopulmonary responses measured with the Aquatrainer system were significantly lower for: VO(2) (2,799 +/- 751 vs. 3,294 +/- 821 ml min(-1), P &lt; 0.0001), VCO(2) (3,426 +/- 836 vs. 3,641 +/- 946 ml min(-1), P = 0.012), VE (98 +/- 21 vs. 108 +/- 26 l min(-1), P = 0.0009) relative to facemask.	vo(2)	115-120	CD59 molecule (CD59 blood group)	Homo sapiens	157-163
20049481-5	2010	At maximal intensity, cardiopulmonary responses measured with the Aquatrainer system were significantly lower for: VO(2) (2,799 +/- 751 vs. 3,294 +/- 821 ml min(-1), P &lt; 0.0001), VCO(2) (3,426 +/- 836 vs. 3,641 +/- 946 ml min(-1), P = 0.012), VE (98 +/- 21 vs. 108 +/- 26 l min(-1), P = 0.0009) relative to facemask.	vo(2)	115-120	CD59 molecule (CD59 blood group)	Homo sapiens	225-231
20049481-5	2010	At maximal intensity, cardiopulmonary responses measured with the Aquatrainer system were significantly lower for: VO(2) (2,799 +/- 751 vs. 3,294 +/- 821 ml min(-1), P &lt; 0.0001), VCO(2) (3,426 +/- 836 vs. 3,641 +/- 946 ml min(-1), P = 0.012), VE (98 +/- 21 vs. 108 +/- 26 l min(-1), P = 0.0009) relative to facemask.	vo(2)	115-120	CD59 molecule (CD59 blood group)	Homo sapiens	225-231
20156668-4	2010	Remifentanil was administered at a dose of 0.5 microg x kg(-1) x min(-1) to obtain analgesia and a &lt;2 surgical field level in Fromme"s modified scale.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	65-71
20486575-4	2010	Under continuous infusion of remifentanil at 0.1-0.2 microg x kg(-1) x min(-1), the patient became sedated while spontaneously breathing, and her pain and laryngeal reflexes were reduced.	Remifentanil	29-41	CD59 molecule (CD59 blood group)	Homo sapiens	71-77
20646415-7	2010	(3) Compared with that before treatment, the glucose infusion ratio in the clamp test [(3.46 +- 1.66) mg x kg-1 x min-1 increased to (7.14 +- 2.37) mg x kg-1 x min-1] and HOMA-beta elevated, while HOMA-IR declined (P &lt; 0.05 or 0.01 in all).	Glucose	45-52	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
20646415-7	2010	(3) Compared with that before treatment, the glucose infusion ratio in the clamp test [(3.46 +- 1.66) mg x kg-1 x min-1 increased to (7.14 +- 2.37) mg x kg-1 x min-1] and HOMA-beta elevated, while HOMA-IR declined (P &lt; 0.05 or 0.01 in all).	Glucose	45-52	CD59 molecule (CD59 blood group)	Homo sapiens	160-165
20026114-8	2010	In CMA whole-blood measurements, splanchnic oxygen consumption (44.8 +/- 4.3 mL/min/1.73 m(2) BS) was slightly lower than in controls (57.5 +/- 8.4 mL/min/1.73 m(2) BS; P = NS).	Oxygen	44-50	CD59 molecule (CD59 blood group)	Homo sapiens	80-85
20155763-3	2010	Gamma radiolysis of water was used to generate HO*/O(2)(*-) free radicals (I = 10 Gy.min(-1), dose = 400 Gy).	Water	20-25	CD59 molecule (CD59 blood group)	Homo sapiens	85-91
20233687-5	2010	Results indicated competition exercise performance was significantly increased 4.2% (+49 sec; p&lt;0.05) as was peak VO2 response 4.4% (+2.5 ml O2 x kg(-1) x min(-1); p&lt;0.05) versus non-competition.	Oxygen	118-120	CD59 molecule (CD59 blood group)	Homo sapiens	158-164
20426274-6	2010	It was observed that about 76% of the boron in the leachate solution could be recovered at an inlet boron concentration of 250 mg L(-1), a flow rate of 2.5 mL min(-1), a pH value of 8.0 and a temperature of 25 degrees C.	Boron	38-43	CD59 molecule (CD59 blood group)	Homo sapiens	159-165
20229758-3	2010	She received landiolol continuous infusion at a rate of 5 microg x kg x min(-1) to 8 microg x kg x min(-1) until the uneventful delivery of the infant with good Apgar score, under combined spinal epidural anesthesia (CESA).	landiolol	13-22	CD59 molecule (CD59 blood group)	Homo sapiens	72-78
19627530-6	2010	Remifentanil, a drug cleared by hydrolysis, can be modeled in all age groups by simple application of this model using a standardized clearance of 2790 ml x min(-1) for a 70-kg person.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	157-163
19627530-10	2010	Propofol maturation has been described with a mature clearance of 1.83 l x min(-1) x 70 kg(-1), a maturation half-time (TM(50)) of 44 weeks and a Hill coefficient of 4.9.	Propofol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	75-81
20086276-5	2010	Cycle-averaged VFR at the CCA, ICA and ECA were 389 +/- 74, 245 +/- 61 and 125 +/- 49 mL min(-1), respectively, reflecting a significant cycle-averaged outflow deficit of 5%, which peaked at around 10% during systole.	ethyl 4-chloro-3-oxobutanoate	39-42	CD59 molecule (CD59 blood group)	Homo sapiens	89-95
20103330-8	2010	RESULTS: Fenoldopam infusion at doses more than 0.1 microg x kg(-1) x min(-1) significantly increases blood flow in all renal compartments, thus improving the resistive and pulsatility indexes starting at a dose of 0.1 microg x kg(-1) x min(-1).	Fenoldopam	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	70-76
20103330-8	2010	RESULTS: Fenoldopam infusion at doses more than 0.1 microg x kg(-1) x min(-1) significantly increases blood flow in all renal compartments, thus improving the resistive and pulsatility indexes starting at a dose of 0.1 microg x kg(-1) x min(-1).	Fenoldopam	9-19	CD59 molecule (CD59 blood group)	Homo sapiens	237-243
20103330-12	2010	CONCLUSIONS: In hemodynamically stable patients undergoing cardiac surgery with preserved renal function, fenoldopam shows a pharmacodynamic dose-dependent profile: it significantly increases renal flow and reduces the resistances of the renal circulation starting at a dose of 0.1 microg x kg(-1) x min(-1).	Fenoldopam	106-116	CD59 molecule (CD59 blood group)	Homo sapiens	300-306
20384131-2	2010	The optimizing experimental conditions were as follows: the mixture of ionic liquid 1-hexyl-3-methylimidazo lium hexafluorophosphats and ethyl acetate ([Hmim] PF6-EA, phi = 1/0.9) can be used as flotation solvent, Fe(III) ion was as trapping agent, pH of test solution was 7.6, the gas flow rate was 40 mL x min(-1), and the flotation time was 50 min.	1-hexyl-3-methylimidazo lium hexafluorophosphats	84-132	CD59 molecule (CD59 blood group)	Homo sapiens	308-314
19927033-4	2010	RESULTS: Both analyses (cross-sectional data followed by longitudinal data) showed a significant decline in peak oxygen consumption with age (0.03 and 0.04 L x min(-1) x yr(-1)), which was related to an age-associated decline in HRmax (0.97 and 0.81 beats per year) and peak oxygen pulse (0.13 and 0.08 mL per beat per year).	Oxygen	113-119	CD59 molecule (CD59 blood group)	Homo sapiens	160-166
20039082-3	2010	Continuous administration of landiolol hydrochloride at a dose of 0.005 mg kg(-1) min(-1) after a loading dose of 0.04 mg kg(-1) min(-1) for 1 min resulted in control of heart rate without a decrease in blood pressure.	landiolol	29-52	CD59 molecule (CD59 blood group)	Homo sapiens	82-88
20039082-3	2010	Continuous administration of landiolol hydrochloride at a dose of 0.005 mg kg(-1) min(-1) after a loading dose of 0.04 mg kg(-1) min(-1) for 1 min resulted in control of heart rate without a decrease in blood pressure.	landiolol	29-52	CD59 molecule (CD59 blood group)	Homo sapiens	129-135
20078813-5	2010	After induction with propofol, anesthesia was maintained with 150 microg x kg(-1) x min(-1) propofol infusion.	Propofol	92-100	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
20078813-6	2010	The propofol infusion rate was altered by 20 microg x kg(-1) x min(-1) to maintain the systolic blood pressure within 20% of the baseline (SP group) or BIS value between 45 and 60 (BIS group).	Propofol	4-12	CD59 molecule (CD59 blood group)	Homo sapiens	63-69
20608209-7	2010	RESULTS: Mean cardiac output measured by thermodilution [CO(S-G)] was 4.59 +/- 2.5 L min(-1), compared to 4.49 +/- 1.14 L min(-1) obtained from contour wave [CO(CW)] and 4.57 +/- 1.29 L min(-1) from continuous-wave [CO(PW)] analysis.	co(s-g)	57-64	CD59 molecule (CD59 blood group)	Homo sapiens	85-91
19779734-3	2010	Exogenous glucose oxidation peaked at ~200 mg min(-1) at the lowest glucose ingestion rate (~400 mg min(-1)).	Glucose	10-17	CD59 molecule (CD59 blood group)	Homo sapiens	46-52
19779734-3	2010	Exogenous glucose oxidation peaked at ~200 mg min(-1) at the lowest glucose ingestion rate (~400 mg min(-1)).	Glucose	10-17	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
19779734-3	2010	Exogenous glucose oxidation peaked at ~200 mg min(-1) at the lowest glucose ingestion rate (~400 mg min(-1)).	Glucose	68-75	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
19138863-7	2009	Vertical impulse over the extension phase was lower (p&lt;0.05) while backward horizontal impulse was higher (p&lt;0.05) during unloaded condition than those extrapolated to 0 W. Oxygen consumptions were higher during unloaded condition than extrapolated to 0 W (750+/-147 vs. 529+/-297 mLO(2) x min(-1); p&lt;0.05).	Oxygen	179-185	CD59 molecule (CD59 blood group)	Homo sapiens	296-302
20169954-9	2010	RESULTS: The dose of propofol was less in the PR group than in the PF group (0.10 +/- 0.04 mg x kg(-1) x min(-1) vs. 0.14 +/- 0.04 mg x kg(-1) x min(-1), P = 0.025).	Propofol	21-29	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
20169954-9	2010	RESULTS: The dose of propofol was less in the PR group than in the PF group (0.10 +/- 0.04 mg x kg(-1) x min(-1) vs. 0.14 +/- 0.04 mg x kg(-1) x min(-1), P = 0.025).	Propofol	21-29	CD59 molecule (CD59 blood group)	Homo sapiens	145-151
20054739-10	2010	The mean difference in VO(2max) change from pre to post between groups (quercetin vs. placebo) was 0.139 ml x kg(-1) x min(-1) (P = 0.780).	Quercetin	72-81	CD59 molecule (CD59 blood group)	Homo sapiens	119-125
20106363-6	2010	The high lactate group showed significantly lower weight-indexed cardiopulmonary bypass flow rate (101 + or - 6.5 mL/kg(-1)/min(-1) vs 131 + or - 6.0 mL/kg(-1)/min(-1), P = .0013), oxygen delivery during cardiopulmonary bypass (mean 12.7 + or - 0.	Lactic Acid	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	124-130
20106363-6	2010	The high lactate group showed significantly lower weight-indexed cardiopulmonary bypass flow rate (101 + or - 6.5 mL/kg(-1)/min(-1) vs 131 + or - 6.0 mL/kg(-1)/min(-1), P = .0013), oxygen delivery during cardiopulmonary bypass (mean 12.7 + or - 0.	Lactic Acid	9-16	CD59 molecule (CD59 blood group)	Homo sapiens	160-166
20077774-4	2010	RESULTS: The patients in PR group were infused remifentanil by 0.22 +/- 0.06 microg x kg(-1) x min(-1) and all needed controlled ventilation with laryngeal mask airway.	Remifentanil	47-59	CD59 molecule (CD59 blood group)	Homo sapiens	95-101
19825011-7	2010	Remifentanil pharmacokinetics was described with a two-compartment model, parameter estimates were 2.99 l x min(-1) x 70 kg(-1) for clearance and 16.23 l x 70 kg(-1) for steady state volume of distribution.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
20418617-4	2010	Residual oxygen was rapidly consumed at a rate, r(O(2)), of 0.35 mg O(2) l(-1) min(-1).	Oxygen	9-15	CD59 molecule (CD59 blood group)	Homo sapiens	79-85
21351457-5	2010	The K(m), V(max), CL(int) and T1/2 of thienorphine obtained from human liver microsomes were (4.00 +/- 0.59) micromol x L(-1), (0.21 +/- 0.06) micromol x L(-1) x min(-1), (117 +/- 3.19) mL x min(-1) x kg(-1) and (223 +/- 6.10) min, respectively.	thienorphine	38-50	CD59 molecule (CD59 blood group)	Homo sapiens	162-168
21351457-5	2010	The K(m), V(max), CL(int) and T1/2 of thienorphine obtained from human liver microsomes were (4.00 +/- 0.59) micromol x L(-1), (0.21 +/- 0.06) micromol x L(-1) x min(-1), (117 +/- 3.19) mL x min(-1) x kg(-1) and (223 +/- 6.10) min, respectively.	thienorphine	38-50	CD59 molecule (CD59 blood group)	Homo sapiens	191-197
19660889-5	2009	Experimental conditions were 40 degrees C for temperature, 11 MPa for pressure, and a CO2 flow rate of 30 ml min(-1).	N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide	86-89	CD59 molecule (CD59 blood group)	Homo sapiens	109-115
19958870-4	2009	METHODS: A computerized algorithm was implemented in January 2006 to calculate appropriate eptifibatide infusion dose (1 microg kg(-1) min(-1) for creatinine clearance &lt;50 mL/min or 2 microg kg(-1) min(-1) for creatinine clearance &gt;or=50 mL/min) using the Cockroft-Gault formula.	Creatinine	147-157	CD59 molecule (CD59 blood group)	Homo sapiens	135-141
19952445-6	2009	The second-order rate constants (k") for the caffeine inhibited reactions lie in the range of 0.13 to 5.10x10(-3) M(-1) min(-1).	Caffeine	45-53	CD59 molecule (CD59 blood group)	Homo sapiens	120-126
20187399-3	2009	N2 stripping was used to remove H2S produced in the reactor, and the average diameter of granular sludge increased to 1.51 mm quickly when N2 stripping with the flux of 60 mL x min(-1) was used, but it decreased when the flux of N2 improved to 100 mL x min(-1).	Nitrogen	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	177-183
20187399-3	2009	N2 stripping was used to remove H2S produced in the reactor, and the average diameter of granular sludge increased to 1.51 mm quickly when N2 stripping with the flux of 60 mL x min(-1) was used, but it decreased when the flux of N2 improved to 100 mL x min(-1).	Nitrogen	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	253-259
20187399-3	2009	N2 stripping was used to remove H2S produced in the reactor, and the average diameter of granular sludge increased to 1.51 mm quickly when N2 stripping with the flux of 60 mL x min(-1) was used, but it decreased when the flux of N2 improved to 100 mL x min(-1).	Nitrogen	139-141	CD59 molecule (CD59 blood group)	Homo sapiens	177-183
20187399-3	2009	N2 stripping was used to remove H2S produced in the reactor, and the average diameter of granular sludge increased to 1.51 mm quickly when N2 stripping with the flux of 60 mL x min(-1) was used, but it decreased when the flux of N2 improved to 100 mL x min(-1).	Nitrogen	139-141	CD59 molecule (CD59 blood group)	Homo sapiens	253-259
19940820-9	2009	The mean propofol dose was higher in the PVB group (52.03+/-19.32 [35-73] mg x kg x min-1) than in the SA group (44.0+/-18.8 [33-70] mg x kg x min-1) (P=0.002).	Propofol	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
19940820-9	2009	The mean propofol dose was higher in the PVB group (52.03+/-19.32 [35-73] mg x kg x min-1) than in the SA group (44.0+/-18.8 [33-70] mg x kg x min-1) (P=0.002).	Propofol	9-17	CD59 molecule (CD59 blood group)	Homo sapiens	143-148
19940820-9	2009	The mean propofol dose was higher in the PVB group (52.03+/-19.32 [35-73] mg x kg x min-1) than in the SA group (44.0+/-18.8 [33-70] mg x kg x min-1) (P=0.002).	pvb	41-44	CD59 molecule (CD59 blood group)	Homo sapiens	84-89
19570607-4	2009	Photocatalytic removal of phenol was maximum at the circulative flow rate of 600 ml min(-1) and the transmittance of 0.3%.	Phenol	26-32	CD59 molecule (CD59 blood group)	Homo sapiens	84-90
19463836-4	2009	After treatment with ethyl methanesulfonate (EMS) many cells have an intermediate level of CD59 staining.	Ethyl Methanesulfonate	21-43	CD59 molecule (CD59 blood group)	Homo sapiens	91-95
19463836-7	2009	Interestingly, about 60% of the CD59 negative clones were actually GPI mutants determined by staining with the GPI specific fluorescently labeled bacterial toxin aerolysin (FLAER).	Glycosylphosphatidylinositols	67-70	CD59 molecule (CD59 blood group)	Homo sapiens	32-36
19570607-5	2009	Integration of circulative photocatalytic treatment and titanium dioxide separation and continuous use of titanium dioxide could be performed effectively at low inflow of 10 ml min(-1).	titanium dioxide	56-72	CD59 molecule (CD59 blood group)	Homo sapiens	177-183
19570607-5	2009	Integration of circulative photocatalytic treatment and titanium dioxide separation and continuous use of titanium dioxide could be performed effectively at low inflow of 10 ml min(-1).	titanium dioxide	106-122	CD59 molecule (CD59 blood group)	Homo sapiens	177-183
19801779-3	2009	By applying an average laser power of 50 W and pulse durations below 10 ps, up to 5 mg min(-1) of nanoparticles have been generated directly in acetone, marking a breakthrough in productivity of ultra-short-pulsed laser ablation in liquids.	Acetone	144-151	CD59 molecule (CD59 blood group)	Homo sapiens	87-93
19713250-11	2009	k(e)(0) values for desflurane (P(K) based: 0.30 +/- 0.17min(-1); area based: 0.32 +/- 0.25 min(-1)) were significantly higher than for isoflurane and sevoflurane.	Desflurane	19-29	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
19841299-5	2009	Iloprost 1 ng kg(-1) min(-1) or placebo was administered intravenously beginning 30 to 90 minutes before and ending 4 hours after the procedure.	Iloprost	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	21-27
19841299-9	2009	In the iloprost group, the estimated glomerular filtration rate increased marginally from 47.5+/-14.5 to 48.6+/-16.1 mL min(-1) 1.73 m(-2) (P=0.26).	Iloprost	7-15	CD59 molecule (CD59 blood group)	Homo sapiens	120-126
19841299-10	2009	The mean absolute estimated glomerular filtration rate decline in the control group was greater than its change in the iloprost group (difference, 4.2 mL min(-1) 1.73 m(-2); 95% confidence interval, 1.1 to 7.3; P=0.008).	Iloprost	119-127	CD59 molecule (CD59 blood group)	Homo sapiens	154-160
19916996-6	2009	Median oxazepam apparent oral clearance was significantly lower in 85YY subjects (1.62 ml min(-1) kg(-1)) compared with 85DD subjects (3.35 ml min(-1) kg(-1); P= 0.003, Student-Newman-Keuls test), whereas 85DY subjects were intermediate (2.34 ml min(-1) kg(-1); P= 0.018 vs. 85DD, P= 0.034 vs. 85YY).	Oxazepam	7-15	CD59 molecule (CD59 blood group)	Homo sapiens	90-96
19667975-6	2009	During the tests, choreic dyskinesias were associated with a central levodopa influx of 10 x 10(-3) nmol min(-1) g(-1) or greater, and foot dystonia occurred with a central levodopa influx less than 9 x 10(-3) nmol min(-1) g(-1).	Levodopa	69-77	CD59 molecule (CD59 blood group)	Homo sapiens	105-114
19567476-6	2009	L-NMMA-induced renal vasoconstriction was more pronounced in females compared to males (-89 +/- 69 versus -60 +/- 52 ml/min/1.73 m(2), P = 0.03).	omega-N-Methylarginine	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	120-125
19567476-7	2009	After administration of L-arginine to restore baseline perfusion, the co-infusion of vitamin C led to a lesser increase of RPF in females than in males (+37 +/- 86 versus +60 +/- 52 ml/min/1.73 m(2), P = 0.05).	Ascorbic Acid	85-94	CD59 molecule (CD59 blood group)	Homo sapiens	185-190
20006797-4	2009	In a subsample of this cohort without renal disease, followed up to 23 years, creatinine clearance declined by a mean of -0.75 mL/min/1.73 m(2) per year.	Creatinine	78-88	CD59 molecule (CD59 blood group)	Homo sapiens	130-135
19805651-13	2009	Valsartan reduced estimated glomerular filtration rate compared with placebo to a similar extent (P=0.52) in the subgroups with CKD (mean reduction -3.6 mL x min(-1) x 1.73 m(-2)) and without CKD (mean reduction -4.0 mL x min(-1) x 1.73 m(-2)) and by -3.8 mL x min(-1) x 1.73 m(-2) in both groups combined.	Valsartan	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	158-164
19805651-13	2009	Valsartan reduced estimated glomerular filtration rate compared with placebo to a similar extent (P=0.52) in the subgroups with CKD (mean reduction -3.6 mL x min(-1) x 1.73 m(-2)) and without CKD (mean reduction -4.0 mL x min(-1) x 1.73 m(-2)) and by -3.8 mL x min(-1) x 1.73 m(-2) in both groups combined.	Valsartan	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	222-228
19805651-13	2009	Valsartan reduced estimated glomerular filtration rate compared with placebo to a similar extent (P=0.52) in the subgroups with CKD (mean reduction -3.6 mL x min(-1) x 1.73 m(-2)) and without CKD (mean reduction -4.0 mL x min(-1) x 1.73 m(-2)) and by -3.8 mL x min(-1) x 1.73 m(-2) in both groups combined.	Valsartan	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	222-228
19767764-8	2009	The Km and Vmax values for cardamonin hydroxylation were calculated as 32 micromol/L and 35 pmol x min(-1) x mg(-1), respectively.	cardamonin	27-37	CD59 molecule (CD59 blood group)	Homo sapiens	99-105
19657101-8	2009	However, following heat acclimation, the pilocarpine-induced sweat rate in the control arm increased 18% to 0.77 +/- 0.21 mg x cm(-2) x min(-1) (P = 0.021) but decreased 52% to 0.32 +/- 0.18 mg x cm(-2) x min(-1) (P &lt; 0.001) in the BOTOX-treated arm.	Pilocarpine	41-52	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
19657101-8	2009	However, following heat acclimation, the pilocarpine-induced sweat rate in the control arm increased 18% to 0.77 +/- 0.21 mg x cm(-2) x min(-1) (P = 0.021) but decreased 52% to 0.32 +/- 0.18 mg x cm(-2) x min(-1) (P &lt; 0.001) in the BOTOX-treated arm.	Pilocarpine	41-52	CD59 molecule (CD59 blood group)	Homo sapiens	205-211
19727688-2	2009	An optimum loading flow rate of 2.25 mL min(-1) for 2 min and an elution flow rate of 2.25 mL min(-1) for 1 min gave an enrichment factor of 15 for nickel.	Nickel	148-154	CD59 molecule (CD59 blood group)	Homo sapiens	40-46
19727688-2	2009	An optimum loading flow rate of 2.25 mL min(-1) for 2 min and an elution flow rate of 2.25 mL min(-1) for 1 min gave an enrichment factor of 15 for nickel.	Nickel	148-154	CD59 molecule (CD59 blood group)	Homo sapiens	94-100
19727688-3	2009	However, a low dynamic capacity and/or rate for adsorption and desorption was found for lead ionic imprinted polymer and a flow rate of 3.00 mL min(-1) for 4-min loading and a flow rate of 2.25 mL min(-1) for 1-min elution gave a enrichment factor of 5.	Polymers	109-116	CD59 molecule (CD59 blood group)	Homo sapiens	197-203
19735400-6	2009	Both mean and maximum blood flow increased significantly in the anastomosed artery at dobutamine infusions of 4 and 6 microg x kg(-1) x min(-1) and this was accompanied by increased cardiac output.	Dobutamine	86-96	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
19660275-8	2009	When long-term survival of patient groups was compared with expected survival, only patients with a creatinine clearance less than 30 mL x min(-1) showed a worse outcome.	Creatinine	100-110	CD59 molecule (CD59 blood group)	Homo sapiens	139-145
19660275-9	2009	Patients with a creatinine clearance between 60 and 90 mL x min(-1) had a long-term survival exceeding the expected survival.	Creatinine	16-26	CD59 molecule (CD59 blood group)	Homo sapiens	60-66
19968085-3	2009	At the background of administration of the heparin at a dose of 0.2-0.3 U x kg(-1) min(-1), urokinase was intravenously administered with a loading dose of 15-20 U x kg(-1) x min(-1) and a locked time period of 30 minutes, and then the dose was incessantly decreased to 4-10 U x kg(-1) x min(-1).	Heparin	43-50	CD59 molecule (CD59 blood group)	Homo sapiens	83-89
19860224-4	2009	In R group, remifentanil was administered at 0.2 microg x kg(-1) x min(-1) from the induction of anesthesia.	Remifentanil	12-24	CD59 molecule (CD59 blood group)	Homo sapiens	67-73
19702213-3	2009	Anesthesia was induced with propofol, suxamethonium and remifentanil 0.26 microg x kg(-1) x min(-1).	Remifentanil	56-68	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
19860242-11	2009	SpO2 was 85-93% with O2 inhalation at 1l x min(-1) during the operation.	spo2	0-4	CD59 molecule (CD59 blood group)	Homo sapiens	43-49
19860242-11	2009	SpO2 was 85-93% with O2 inhalation at 1l x min(-1) during the operation.	Oxygen	2-4	CD59 molecule (CD59 blood group)	Homo sapiens	43-49
19639375-11	2009	CONCLUSIONS: An infusion rate of 120 microg x kg(-1) x min(-1) is clinically practical and capable of achieving experimental cardioprotective propofol concentrations at reperfusion.	Propofol	142-150	CD59 molecule (CD59 blood group)	Homo sapiens	55-61
19608703-5	2009	Compared with the control group, decline in CrCl was slower with bicarbonate supplementation (5.93 versus 1.88 ml/min 1.73 m(2); P &lt; 0.0001).	Bicarbonates	65-76	CD59 molecule (CD59 blood group)	Homo sapiens	114-119
19494026-5	2009	The plasma inositol concentration was 175.74 (59.71-300.60) micromol/L and Ra was 1.06 (0.33-1.75) micromol x kg(-1).min(-1) (1521 micromol x kg(-1) x d(-1)).	Inositol	11-19	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
19494026-5	2009	The plasma inositol concentration was 175.74 (59.71-300.60) micromol/L and Ra was 1.06 (0.33-1.75) micromol x kg(-1).min(-1) (1521 micromol x kg(-1) x d(-1)).	Radium	75-77	CD59 molecule (CD59 blood group)	Homo sapiens	117-123
19360725-3	2009	Polylactide (PLA)-drug nanoparticles with average diameters of around 200 nm are achieved in a stable cone-jet mode with a flow rate of 4 microL min(-1), polymer concentration of 1%, and ammonium hydroxide content of 0.05%.	poly(lactide)	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	145-151
19418417-10	2009	For example, at a blood glucose concentration of 11 mmol x l(-1) renal glucose excretion ranged from 163 micromol x min(-1) to 25 micromol x min(-1) in subjects exhibiting a low to high VRT (G), thus showing a variability &gt;factor 6.	Glucose	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	116-122
19418417-10	2009	For example, at a blood glucose concentration of 11 mmol x l(-1) renal glucose excretion ranged from 163 micromol x min(-1) to 25 micromol x min(-1) in subjects exhibiting a low to high VRT (G), thus showing a variability &gt;factor 6.	Glucose	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	141-147
19454587-7	2009	210 min(-1)) the EAA ingestion.	Amino Acids, Essential	17-20	CD59 molecule (CD59 blood group)	Homo sapiens	4-10
19512873-4	2009	Neuromuscular blockade was induced by bolus injection of 0.6 mg/kg rocuronium followed by continuous infusion of 7 microg x kg(-1) x min(-1) rocuronium adjusted to maintain a neuromuscular blockade depth of zero response to train-of-four and a posttetanic count of no more than 10 responses.	Rocuronium	141-151	CD59 molecule (CD59 blood group)	Homo sapiens	133-139
19307230-7	2009	Alcohol intake of &gt;or=30 g/day was associated with an increased risk of albuminuria after adjustment for age, sex and baseline kidney function (OR = 1.59, 95% CI 1.07-2.36), but a reduced risk of eGFR &lt;60 mL/min/1.73 m(2) (OR = 0.59, 95% CI 0.37-0.95), compared with consumption of &lt;10 g/day.	Alcohols	0-7	CD59 molecule (CD59 blood group)	Homo sapiens	214-219
19053964-4	2009	RESULTS: Arterial lactate and cardiac output increased to 15.3 +/- 4.2 mM and 20.8 +/- 1.5 L min(-1) respectively (mean +/- SD).	Lactic Acid	18-25	CD59 molecule (CD59 blood group)	Homo sapiens	93-99
19053964-6	2009	Propranolol reduced resting heart rate (58 +/- 6 vs. 69 +/- 8 beats min(-1)) and at exercise exhaustion, cardiac output (16.6 +/- 3.6 L min(-1)) and arterial lactate (9.4 +/- 3.7 mM) were attenuated with a reduction in exercise capacity from 239 +/- 42 to 209 +/- 31 W (all P &lt; 0.05).	Propranolol	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
19053964-6	2009	Propranolol reduced resting heart rate (58 +/- 6 vs. 69 +/- 8 beats min(-1)) and at exercise exhaustion, cardiac output (16.6 +/- 3.6 L min(-1)) and arterial lactate (9.4 +/- 3.7 mM) were attenuated with a reduction in exercise capacity from 239 +/- 42 to 209 +/- 31 W (all P &lt; 0.05).	Propranolol	0-11	CD59 molecule (CD59 blood group)	Homo sapiens	136-142
19577083-7	2009	In contrast, left ventricular ejection fraction and cardiac index in the PAH group (50.9% +/- 3.7%, 2.66 +/- 0.12 L x min(-1) x m(-2)) were still significantly lower than in the non-PAH group (65.4% +/- 2.8%, 3.13 +/- 0.15 L x min(-1) x m(-2)) (P = .0038, .037).	p-Aminohippuric Acid	73-76	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
19577083-7	2009	In contrast, left ventricular ejection fraction and cardiac index in the PAH group (50.9% +/- 3.7%, 2.66 +/- 0.12 L x min(-1) x m(-2)) were still significantly lower than in the non-PAH group (65.4% +/- 2.8%, 3.13 +/- 0.15 L x min(-1) x m(-2)) (P = .0038, .037).	p-Aminohippuric Acid	73-76	CD59 molecule (CD59 blood group)	Homo sapiens	227-233
19715926-11	2009	Mean serum creatinine was 1.44 mg/dL with Modification of Diet in Renal Disease (MDRD) clearance of 76 mL/min/1.73 m(2).	Creatinine	11-21	CD59 molecule (CD59 blood group)	Homo sapiens	106-111
19411667-4	2009	METHODS: Seventy women were randomized in two groups to receive either phenylephrine at a rate of 16.6 microg min(-1) (concentration 1microg ml(-1)) or ephedrine at a rate of 1.5 mg min(-1) (concentration 90 microg ml(-1)).	Phenylephrine	71-84	CD59 molecule (CD59 blood group)	Homo sapiens	110-116
19615129-10	2009	In PSV group, the area under receiver operating characteristic (ROC) curve of RSBI was 0.747+/-0.045 (P = 0.000); when RSBI =75 breaths x min(-1) x L(-1), the diagnostic accuracy was 87%; the area under ROC curve of Delta RSBI was 0.709+/-0.065 (P = 0.001), and when Delta RSBI=90%, the diagnostic accuracy was 82%.	alpha-D-Psicofuranose	3-6	CD59 molecule (CD59 blood group)	Homo sapiens	138-144
19386604-7	2009	Treatment with H(2)O(2) reduced surface expression of the complement inhibitors DAF, CD55, and CD59, and impaired regulation at the cell surface by factor H present within the serum.	Hydrogen Peroxide	15-23	CD59 molecule (CD59 blood group)	Homo sapiens	95-99
19458858-8	2009	With an applied voltage of 2.5 V, the maximum pumping rate for DI water and whole blood were 121 nl min(-1) and 88 nl min(-1), respectively, with a channel cross section of 100 x 50 microm.	Water	66-71	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
19458858-8	2009	With an applied voltage of 2.5 V, the maximum pumping rate for DI water and whole blood were 121 nl min(-1) and 88 nl min(-1), respectively, with a channel cross section of 100 x 50 microm.	Water	66-71	CD59 molecule (CD59 blood group)	Homo sapiens	118-124
19413822-6	2009	At a flow of 2 l x min(-1), oxygen concentrations exceeded 23% only within a few centimetres of the nasal cannula.	Oxygen	28-34	CD59 molecule (CD59 blood group)	Homo sapiens	19-25
19384212-7	2009	The mean (sd) norepinephrine dose increased from 0.18 (0.18) microg x kg(-1) x min(-1) at 60 mm Hg to 0.41 (0.26) microg x kg(-1) x min(-1) at 90 mm Hg (p &lt; 0.0001).	Norepinephrine	14-28	CD59 molecule (CD59 blood group)	Homo sapiens	79-85
19384212-7	2009	The mean (sd) norepinephrine dose increased from 0.18 (0.18) microg x kg(-1) x min(-1) at 60 mm Hg to 0.41 (0.26) microg x kg(-1) x min(-1) at 90 mm Hg (p &lt; 0.0001).	Norepinephrine	14-28	CD59 molecule (CD59 blood group)	Homo sapiens	132-138
19294410-4	2009	Over the first period, maximal oxygen uptake (VO(2max)) remained above 6 l min(-1) which is an outstanding value.	Oxygen	31-37	CD59 molecule (CD59 blood group)	Homo sapiens	75-81
21383461-7	2009	Characteristic (median) values for breath isoprene concentration and molar flow, i.e., the amount of isoprene exhaled per minute are 100 ppb and 29 nmol min(-1), respectively, with some intra-individual day-to-day variation.	isoprene	42-50	CD59 molecule (CD59 blood group)	Homo sapiens	153-159
21383461-7	2009	Characteristic (median) values for breath isoprene concentration and molar flow, i.e., the amount of isoprene exhaled per minute are 100 ppb and 29 nmol min(-1), respectively, with some intra-individual day-to-day variation.	isoprene	101-109	CD59 molecule (CD59 blood group)	Homo sapiens	153-159
19403604-6	2009	Total body noradrenaline spillover was 605.8 ng min(-1) +/- 34.4 ng min(-1).	Norepinephrine	11-24	CD59 molecule (CD59 blood group)	Homo sapiens	48-54
19403604-6	2009	Total body noradrenaline spillover was 605.8 ng min(-1) +/- 34.4 ng min(-1).	Norepinephrine	11-24	CD59 molecule (CD59 blood group)	Homo sapiens	68-74
19522262-4	2009	Remifentanil at the rate of 0.5 microg x kg(-1) x min(-1) was administrated continuously, and tracheal intubation was performed by each anesthesiologist, at various times after administration of remifentanil.	Remifentanil	0-12	CD59 molecule (CD59 blood group)	Homo sapiens	50-56
19522262-10	2009	CONCLUSIONS: During sevoflurane anesthesia, remifentanil infusion at 0.5 microg x kg(-1) x min(-1) for more than 210 sec could provide the effective blocking of the sympathetic response to tracheal intubation with more than 50% probability.	Remifentanil	44-56	CD59 molecule (CD59 blood group)	Homo sapiens	91-97
19522267-5	2009	Infusion rate of remifentanil at the beginning of surgery was 0.24+/-0.02 microg x kg(-1) x min(-1), and minimal and maximal rate were 0.06+/-0.03 and 0.26+/-0.03 microg x kg(-1) min(-1).	Remifentanil	17-29	CD59 molecule (CD59 blood group)	Homo sapiens	92-98
19522267-5	2009	Infusion rate of remifentanil at the beginning of surgery was 0.24+/-0.02 microg x kg(-1) x min(-1), and minimal and maximal rate were 0.06+/-0.03 and 0.26+/-0.03 microg x kg(-1) min(-1).	Remifentanil	17-29	CD59 molecule (CD59 blood group)	Homo sapiens	179-185
19155536-6	2009	RESULTS: The progression rate for regular users of acetaminophen was slower than that for non-regular users (regular users progressed 0.93 mL/min/1.73 m(2) per year slower than non-regular users; 95% CI 0.03, 1.8).	Acetaminophen	51-64	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
19155536-7	2009	For regular users of aspirin, the progression rate was significantly slower than that for non-regular users (regular users progressed 0.80 mL/min/1.73 m(2) per year slower than non-regular users; 95% CI 0.1, 1.5).	Aspirin	21-28	CD59 molecule (CD59 blood group)	Homo sapiens	142-147
19424617-5	2009	Furthermore, treatment of herceptin combined with chemo-agents had advantages over chemotherapy alone, while CD55 and CD59 expression levels both declined remarkably in A549 and H157 cell lines after incubation with IC50 cisplatin for 72 h. Our data indicated that overexpression of mCRPs on tumor cells contributes to herceptin"s acquisition of resistance to NSCLC, and its anticancer efficacy was enhanced when mCRPs were neutralized or cisplatin could be used to down-regulate their expression.	Cisplatin	221-230	CD59 molecule (CD59 blood group)	Homo sapiens	118-122
19260097-4	2009	The annual decline in Fdopa influx constant (Ki, unit x 10(-3) min(-1)) was on average 0.5 during the first 2 years and 0.2 during the subsequent 3 years (P = 0.002) in the contralateral putamen.	fluorodopa F 18	22-27	CD59 molecule (CD59 blood group)	Homo sapiens	63-70
19406336-8	2009	Gadolinium-based MR contrast media should be avoided in the presence of advanced renal failure with estimated glomerular filtration rate below 30 ml/min/1.73 m2, unless the diagnostic information is essential and not available with noncontrast magnetic resonance imaging techniques.	Gadolinium	0-10	CD59 molecule (CD59 blood group)	Homo sapiens	149-154
19468264-7	2009	Oxygen uptake decreased significantly after hormone replacement (24.1+/-6.3 vs 17.1+/-4.2 ml x kg x min(-1); p=0.03).Minute ventilation also showed an enhanced performance in treated patients (28.0+/-8.1 vs 23.5+/-5.6 l x min(-1); p=0.03), as did the heart rate (128+/-17 vs 121+/-17 bpm; p=0.03).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	100-106
19468264-7	2009	Oxygen uptake decreased significantly after hormone replacement (24.1+/-6.3 vs 17.1+/-4.2 ml x kg x min(-1); p=0.03).Minute ventilation also showed an enhanced performance in treated patients (28.0+/-8.1 vs 23.5+/-5.6 l x min(-1); p=0.03), as did the heart rate (128+/-17 vs 121+/-17 bpm; p=0.03).	Oxygen	0-6	CD59 molecule (CD59 blood group)	Homo sapiens	222-228
19462805-3	2009	Anesthesia was induced with bolus infusion of propofol 1 mg x kg(-1) and continuous infusion of remifentanil at 0.15 microg x kg(-1) x min(-1) was started.	Remifentanil	96-108	CD59 molecule (CD59 blood group)	Homo sapiens	135-141
19462805-5	2009	Anesthesia was maintained with sevoflurane (0.4-1.0%), air and oxygen (33-50%) and with continuous infusion of 0.1-0.15 microg x kg(-1) x min(-1) of remifentanil without any muscle relaxant.	Remifentanil	149-161	CD59 molecule (CD59 blood group)	Homo sapiens	138-144
19462805-6	2009	The circulatory status was maintained with 1-5 microg x kg(-1) x min(-1) of dopamine depending on changes of CVP and BP.	Dopamine	76-84	CD59 molecule (CD59 blood group)	Homo sapiens	65-71
19556622-3	2009	The VO2SC was significantly higher in CE (180.5 +/- 155.8 ml x min-1) than in TR (113.0 +/- 84.2 ml x min-1).	vo2sc	4-9	CD59 molecule (CD59 blood group)	Homo sapiens	63-68
19556622-3	2009	The VO2SC was significantly higher in CE (180.5 +/- 155.8 ml x min-1) than in TR (113.0 +/- 84.2 ml x min-1).	vo2sc	4-9	CD59 molecule (CD59 blood group)	Homo sapiens	102-107
19326878-4	2009	The observed rate constants (k(obs) approximately 10(-3) min(-1) for Li(+) and NH(4)(+)) are approximately 1000-fold lower than that in the presence of 10 mM Mg(2+), and approximately 200,000-fold slower than that in the presence of 100 microM Pb(2+).	Lead	244-246	CD59 molecule (CD59 blood group)	Homo sapiens	57-63
19622297-2	2009	This study was to investigate the anti-complement capacity of mutant CD59 (at the W40 site), and its inhibitory effect on ovarian cancer cell line A2780 in combination with lip polysaccharide (LPS).	lip polysaccharide	173-191	CD59 molecule (CD59 blood group)	Homo sapiens	69-73
19299779-6	2009	During emergence, the remifentanil group (infusion rate 0.014 +/- 0.011 microg x kg(-1) x min(-1)) had a significantly lower incidence (40% vs 80%, P = 0.002) and less severe coughing compared with the control group, as well as a lower incidence of nonpurposeful movement (3.3% vs 30%, P = 0.006) and slower heart rates.	Remifentanil	22-34	CD59 molecule (CD59 blood group)	Homo sapiens	90-96