PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
16790489-11	2006	Consumption of dietary EQ produced the expression of CYP3A, glutathione S-transferase (GST), and uridine diphosphate glucuronosyl-transferase (UDPGT) mRNA during the depuration period.	Ethoxyquin	23-25	cytochrome P450 3A27	Salmo salar	53-58
17207528-4	2007	Our data show that OH-PCB congeners and EE2, decreased AhRalpha and ARNT transcript levels, and CYP1A1, UGT and GST gene expressions, together with CYP3A gene expression.	oh-pcb	19-25	cytochrome P450 3A27	Salmo salar	148-153
21354591-9	2011	While PFOS and PFOA produced an apparent time-dependent increase in kidney CYP3A, CYP1A1 and GST expression, similar effects were only temporary in the liver, significantly increasing at sampling day 2.	perfluorooctane sulfonic acid	6-10	cytochrome P450 3A27	Salmo salar	75-80
21354591-9	2011	While PFOS and PFOA produced an apparent time-dependent increase in kidney CYP3A, CYP1A1 and GST expression, similar effects were only temporary in the liver, significantly increasing at sampling day 2.	perfluorooctanoic acid	15-19	cytochrome P450 3A27	Salmo salar	75-80
21354591-12	2011	Overall, the changes in plasma steroid hormone levels parallel changes in CYP3A mRNA levels.	Steroids	31-46	cytochrome P450 3A27	Salmo salar	74-79
17344101-8	2007	The AhRbeta, CYP3A and uridine diphosphoglucuronosyl transferase (UGT) mRNA expressions were significantly induced after exposure to TBT.	tributyltin	133-136	cytochrome P450 3A27	Salmo salar	13-18
17344101-9	2007	Immunochemical analysis of CYP3A and CYP1A1 protein levels confirmed the TBT effects observed at the transcriptional levels.	tributyltin	73-76	cytochrome P450 3A27	Salmo salar	27-32
17344101-12	2007	The induced expression patterns of CYP3A and UGT mRNA after TBT exposure, suggest the involvement of CYP3A and UGT in TBT metabolism in fish.	tributyltin	60-63	cytochrome P450 3A27	Salmo salar	35-40
17344101-12	2007	The induced expression patterns of CYP3A and UGT mRNA after TBT exposure, suggest the involvement of CYP3A and UGT in TBT metabolism in fish.	tributyltin	60-63	cytochrome P450 3A27	Salmo salar	101-106
17344101-12	2007	The induced expression patterns of CYP3A and UGT mRNA after TBT exposure, suggest the involvement of CYP3A and UGT in TBT metabolism in fish.	tributyltin	118-121	cytochrome P450 3A27	Salmo salar	35-40
17344101-12	2007	The induced expression patterns of CYP3A and UGT mRNA after TBT exposure, suggest the involvement of CYP3A and UGT in TBT metabolism in fish.	tributyltin	118-121	cytochrome P450 3A27	Salmo salar	101-106
17344101-13	2007	The effect of TBT on CYP3A is proposed to represent another hormonal effect of TBT not previously reported in any fish or lower vertebrate.	tributyltin	14-17	cytochrome P450 3A27	Salmo salar	21-26
17344101-13	2007	The effect of TBT on CYP3A is proposed to represent another hormonal effect of TBT not previously reported in any fish or lower vertebrate.	tributyltin	79-82	cytochrome P450 3A27	Salmo salar	21-26
16790489-12	2006	A similar pattern of effect was observed for both CYP3A and phase II genes and supports our previous postulation of common regulation of these enzymes by the same inducer, namely EQ metabolites.	Ethoxyquin	179-181	cytochrome P450 3A27	Salmo salar	50-55
16475368-1	2005	Gene expression patterns for key brain steroidogenic (StAR, P450scc, CYP11beta) and xenobiotic- and steroid-metabolizing enzymes (CYP1A1 and CYP3A) have been investigated in waterborne nonylphenol (5, 15, and 50 microg/ L) treated juvenile Atlantic salmon (Salmo salar), in addition to carrier vehicle (ethanol) exposed fish, sampled at different time intervals (0, 3, and 7 days) after exposure.	nonylphenol	185-196	cytochrome P450 3A27	Salmo salar	141-146
16406821-0	2006	The xenoestrogen 4-nonylphenol modulates hepatic gene expression of pregnane X receptor, aryl hydrocarbon receptor, CYP3A and CYP1A1 in juvenile Atlantic salmon (Salmo salar).	4-nonylphenol	17-30	cytochrome P450 3A27	Salmo salar	116-121
16406821-3	2006	Nonylphenol interacts with xenobiotic- and drug-metabolizing CYP forms, including members of the CYP3A and CYP1A1 subfamilies in fish.	nonylphenol	0-11	cytochrome P450 3A27	Salmo salar	97-102
16406821-5	2006	Previously in our laboratory, we have shown that nonylphenol, in addition to inducing plasma egg-yolk and eggshell proteins, also modulates hepatic CYP3A- and CYP1A1-mediated enzyme activities in juvenile Atlantic salmon.	nonylphenol	49-60	cytochrome P450 3A27	Salmo salar	148-153
16406821-7	2006	Our data show that nonylphenol-induced CYP3A and CYP1A1 mRNA levels correlate with PXR and AhR at day 7 post-exposure to 5 and 15 microg NP/L.	nonylphenol	19-30	cytochrome P450 3A27	Salmo salar	39-44
16406821-12	2006	This is the first study that simultaneously examined CYP3A, CYP1A1, PXR and AhR transcripts following nonylphenol treatment in any aquatic species or earlier diverging vertebrates.	nonylphenol	102-113	cytochrome P450 3A27	Salmo salar	53-58
16764480-0	2006	The persistent DDT metabolite, 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene, alters thyroid hormone-dependent genes, hepatic cytochrome P4503A, and pregnane X receptor gene expressions in Atlantic salmon (Salmo salar) Parr.	DDT	15-18	cytochrome P450 3A27	Salmo salar	125-131
16764480-0	2006	The persistent DDT metabolite, 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene, alters thyroid hormone-dependent genes, hepatic cytochrome P4503A, and pregnane X receptor gene expressions in Atlantic salmon (Salmo salar) Parr.	Dichlorodiphenyl Dichloroethylene	31-75	cytochrome P450 3A27	Salmo salar	125-131
16764480-8	2006	Exposure to T4 and DDE, both singly and in combination, resulted in a parallel pattern of CYP3A and PXR mRNA induction in the liver.	Dichlorodiphenyl Dichloroethylene	19-22	cytochrome P450 3A27	Salmo salar	90-95
16764480-10	2006	The hepatic modulation of CYP3A and PXR transcript levels by DDE represents a novel aspect of DDE toxicity that, to our knowledge, has not been demonstrated previously in fish.	Dichlorodiphenyl Dichloroethylene	61-64	cytochrome P450 3A27	Salmo salar	26-31
16764480-10	2006	The hepatic modulation of CYP3A and PXR transcript levels by DDE represents a novel aspect of DDE toxicity that, to our knowledge, has not been demonstrated previously in fish.	Dichlorodiphenyl Dichloroethylene	94-97	cytochrome P450 3A27	Salmo salar	26-31
16475368-8	2005	CYP3A mRNA was significantly induced by all nonylphenol exposure concentrations at day 7.	nonylphenol	44-55	cytochrome P450 3A27	Salmo salar	0-5
16475368-9	2005	When exposed groups were compared, CYP3A transcript was significantly induced between 5 and 15 microg of nonylphenol/ L, and decreased between 15 and 50 microg of nonylphenol/ L. The ethanol control showed a significant reduction of CYP3A mRNA at day 3 postexposure.	nonylphenol	105-116	cytochrome P450 3A27	Salmo salar	35-40
16475368-9	2005	When exposed groups were compared, CYP3A transcript was significantly induced between 5 and 15 microg of nonylphenol/ L, and decreased between 15 and 50 microg of nonylphenol/ L. The ethanol control showed a significant reduction of CYP3A mRNA at day 3 postexposure.	nonylphenol	163-174	cytochrome P450 3A27	Salmo salar	35-40
16475368-9	2005	When exposed groups were compared, CYP3A transcript was significantly induced between 5 and 15 microg of nonylphenol/ L, and decreased between 15 and 50 microg of nonylphenol/ L. The ethanol control showed a significant reduction of CYP3A mRNA at day 3 postexposure.	nonylphenol	163-174	cytochrome P450 3A27	Salmo salar	233-238
16475368-9	2005	When exposed groups were compared, CYP3A transcript was significantly induced between 5 and 15 microg of nonylphenol/ L, and decreased between 15 and 50 microg of nonylphenol/ L. The ethanol control showed a significant reduction of CYP3A mRNA at day 3 postexposure.	Ethanol	183-190	cytochrome P450 3A27	Salmo salar	35-40
16475368-9	2005	When exposed groups were compared, CYP3A transcript was significantly induced between 5 and 15 microg of nonylphenol/ L, and decreased between 15 and 50 microg of nonylphenol/ L. The ethanol control showed a significant reduction of CYP3A mRNA at day 3 postexposure.	Ethanol	183-190	cytochrome P450 3A27	Salmo salar	233-238
28959541-7	2016	ARA and gamma-tocopherol strengthened the contaminant-induced response, ARA by contributing to an additive and synergistic induction of CYP1A, CYP3A and CPT2, and gamma-tocopherol by synergistically increasing ACOX1.	Arabinose	0-3	cytochrome P450 3A27	Salmo salar	143-148
28959541-7	2016	ARA and gamma-tocopherol strengthened the contaminant-induced response, ARA by contributing to an additive and synergistic induction of CYP1A, CYP3A and CPT2, and gamma-tocopherol by synergistically increasing ACOX1.	gamma-Tocopherol	8-24	cytochrome P450 3A27	Salmo salar	143-148