PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
25070639-2	2014	In this study, using a floral stem cell model in Arabidopsis thaliana, we uncovered a role for TOPOISOMERASE1alpha (TOP1alpha) in Polycomb Group (PcG) protein-mediated histone 3 lysine 27 trimethylation (H3K27me3) at, and transcriptional repression of, the stem cell maintenance gene WUSCHEL (WUS).	Lysine	178-184	DNA topoisomerase I alpha	Arabidopsis thaliana	116-125
9477323-6	1998	The strong allele, stm-5, is epistatic to mgo1, showing that the presence of meristematic cells is essential for MGO1 function.	mgo1	42-46	DNA topoisomerase I alpha	Arabidopsis thaliana	113-117
24992598-3	2014	Through a chemical genetics screen with a luciferase-based DNA methylation reporter, LUCL, we found that camptothecin, a compound with anti-cancer properties that targets DNA topoisomerase 1alpha (TOP1alpha) was able to de-repress LUCL by reducing its DNA methylation and H3K9me2 levels.	lucl	85-89	DNA topoisomerase I alpha	Arabidopsis thaliana	171-206
24992598-3	2014	Through a chemical genetics screen with a luciferase-based DNA methylation reporter, LUCL, we found that camptothecin, a compound with anti-cancer properties that targets DNA topoisomerase 1alpha (TOP1alpha) was able to de-repress LUCL by reducing its DNA methylation and H3K9me2 levels.	Camptothecin	105-117	DNA topoisomerase I alpha	Arabidopsis thaliana	171-206
24992598-3	2014	Through a chemical genetics screen with a luciferase-based DNA methylation reporter, LUCL, we found that camptothecin, a compound with anti-cancer properties that targets DNA topoisomerase 1alpha (TOP1alpha) was able to de-repress LUCL by reducing its DNA methylation and H3K9me2 levels.	lucl	231-235	DNA topoisomerase I alpha	Arabidopsis thaliana	171-206
26969721-5	2016	Loss of TOP1alpha function triggers DNA double-strand breaks in S-phase SSCs and results in their death, which can be partially reversed by the replenishment of SSCs mediated by ETHYLENE RESPONSE FACTOR115 In the quiescent center and root cap meristem, TOP1alpha is epistatic to RETINOBLASTOMA-RELATED (RBR) in the maintenance of undifferentiated state and the number of columella stem cells (CSCs).	ethylene	178-186	DNA topoisomerase I alpha	Arabidopsis thaliana	8-17
26969721-5	2016	Loss of TOP1alpha function triggers DNA double-strand breaks in S-phase SSCs and results in their death, which can be partially reversed by the replenishment of SSCs mediated by ETHYLENE RESPONSE FACTOR115 In the quiescent center and root cap meristem, TOP1alpha is epistatic to RETINOBLASTOMA-RELATED (RBR) in the maintenance of undifferentiated state and the number of columella stem cells (CSCs).	ethylene	178-186	DNA topoisomerase I alpha	Arabidopsis thaliana	253-262