PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
19952001-8	2010	Knockouts of SDG8 (carotenoid and chloroplast regulation (ccr1)) and CRTISO (ccr2) result in altered carotenoid composition and this could be restored in ccr2 using the CaMV35s or CRTISO promoters.	Carotenoids	19-29	CRINKLY4 related 2	Arabidopsis thaliana	154-158
19952001-8	2010	Knockouts of SDG8 (carotenoid and chloroplast regulation (ccr1)) and CRTISO (ccr2) result in altered carotenoid composition and this could be restored in ccr2 using the CaMV35s or CRTISO promoters.	Carotenoids	101-111	CRINKLY4 related 2	Arabidopsis thaliana	77-81
19952001-8	2010	Knockouts of SDG8 (carotenoid and chloroplast regulation (ccr1)) and CRTISO (ccr2) result in altered carotenoid composition and this could be restored in ccr2 using the CaMV35s or CRTISO promoters.	Carotenoids	101-111	CRINKLY4 related 2	Arabidopsis thaliana	154-158
18046574-6	2008	The expression of CCR2, a CCR gene usually involved in plant defense, was increased in the mutants and could account for the biosynthesis of lignins in the CCR1-knockout plants.	Lignin	141-148	CRINKLY4 related 2	Arabidopsis thaliana	18-22
7513083-1	1994	We have characterized the expression of two members of a class of Arabidopsis thaliana glycine-rich, putative RNA-binding proteins that we denote Ccr1 and Ccr2.	Glycine	87-94	CRINKLY4 related 2	Arabidopsis thaliana	155-159
7513083-6	1994	Levels of Ccr1 and Ccr2 mRNAs were unchanged in wounded plants, increased at least 4-fold in cold-stressed plants, and decreased 2- to 3-fold in abscisic acid-treated plants.	Abscisic Acid	145-158	CRINKLY4 related 2	Arabidopsis thaliana	19-23
27354553-3	2016	Genome-wide basal and induced transcriptome changes regulated by SDG8 and/or SDG25 showed that two genes of the SDG-dependent transcriptome, CAROTENOID ISOMERASE2 (CCR2) and ECERIFERUM3 (CER3), were also required for plant immunity, establishing mechanisms in defense functions for SDG8 and SDG25.	secoisolariciresinol diglucoside	65-68	CRINKLY4 related 2	Arabidopsis thaliana	164-168
27354553-4	2016	CCR2 catalyzes the biosynthesis of carotenoids, whereas CER3 is involved in the biosynthesis of cuticular wax.	Carotenoids	35-46	CRINKLY4 related 2	Arabidopsis thaliana	0-4
27354553-6	2016	Loss of immunity in sdg mutants was attributed to altered global and CCR2- and CER3-specific histone lysine methylation (HLM).	secoisolariciresinol diglucoside	20-23	CRINKLY4 related 2	Arabidopsis thaliana	69-73
20829305-0	2011	The simultaneous repression of CCR and CAD, two enzymes of the lignin biosynthetic pathway, results in sterility and dwarfism in Arabidopsis thaliana.	Lignin	63-69	CRINKLY4 related 2	Arabidopsis thaliana	31-34
20829305-1	2011	Cinnamoyl CoA reductase (CCR) and cinnamyl alcohol dehydrogenase (CAD) catalyze the last steps of monolignol biosynthesis.	monolignol	98-108	CRINKLY4 related 2	Arabidopsis thaliana	25-28
32689394-7	2007	Herbicide treatments that inhibit carotenoid biosynthetic enzymes in wildtype and ccr2 etiolated seedlings were used to demonstrate that the loss of the PLB in ccr2 mutants is a result of perturbations in carotenoid accumulation, not indirect secondary effects, as PLB formation could be restored in ccr2 mutants treated with norflurazon.	Carotenoids	34-44	CRINKLY4 related 2	Arabidopsis thaliana	160-164
32689394-7	2007	Herbicide treatments that inhibit carotenoid biosynthetic enzymes in wildtype and ccr2 etiolated seedlings were used to demonstrate that the loss of the PLB in ccr2 mutants is a result of perturbations in carotenoid accumulation, not indirect secondary effects, as PLB formation could be restored in ccr2 mutants treated with norflurazon.	Carotenoids	34-44	CRINKLY4 related 2	Arabidopsis thaliana	160-164
32689394-7	2007	Herbicide treatments that inhibit carotenoid biosynthetic enzymes in wildtype and ccr2 etiolated seedlings were used to demonstrate that the loss of the PLB in ccr2 mutants is a result of perturbations in carotenoid accumulation, not indirect secondary effects, as PLB formation could be restored in ccr2 mutants treated with norflurazon.	norflurazone	326-337	CRINKLY4 related 2	Arabidopsis thaliana	160-164
32689394-7	2007	Herbicide treatments that inhibit carotenoid biosynthetic enzymes in wildtype and ccr2 etiolated seedlings were used to demonstrate that the loss of the PLB in ccr2 mutants is a result of perturbations in carotenoid accumulation, not indirect secondary effects, as PLB formation could be restored in ccr2 mutants treated with norflurazon.	norflurazone	326-337	CRINKLY4 related 2	Arabidopsis thaliana	160-164
20876124-3	2010	CCR1 exhibits preference for feruloyl CoA, but CCR2 prefers caffeoyl and 4-coumaroyl CoAs, exhibits sigmoidal kinetics with these substrates, and is substrate-inhibited by feruloyl and sinapoyl CoAs.	caffeoyl	60-68	CRINKLY4 related 2	Arabidopsis thaliana	47-51
20876124-3	2010	CCR1 exhibits preference for feruloyl CoA, but CCR2 prefers caffeoyl and 4-coumaroyl CoAs, exhibits sigmoidal kinetics with these substrates, and is substrate-inhibited by feruloyl and sinapoyl CoAs.	4-coumaroyl-coenzyme A	73-89	CRINKLY4 related 2	Arabidopsis thaliana	47-51
20876124-3	2010	CCR1 exhibits preference for feruloyl CoA, but CCR2 prefers caffeoyl and 4-coumaroyl CoAs, exhibits sigmoidal kinetics with these substrates, and is substrate-inhibited by feruloyl and sinapoyl CoAs.	feruloyl and	172-184	CRINKLY4 related 2	Arabidopsis thaliana	47-51
20876124-3	2010	CCR1 exhibits preference for feruloyl CoA, but CCR2 prefers caffeoyl and 4-coumaroyl CoAs, exhibits sigmoidal kinetics with these substrates, and is substrate-inhibited by feruloyl and sinapoyl CoAs.	sinapoyl-coenzyme A	185-198	CRINKLY4 related 2	Arabidopsis thaliana	47-51
20876124-4	2010	M. truncatula lines harboring transposon insertions in CCR1 exhibit drastically reduced growth and lignin content, whereas CCR2 knockouts grow normally with moderate reduction in lignin levels.	Lignin	179-185	CRINKLY4 related 2	Arabidopsis thaliana	123-127
20876124-7	2010	These observations suggest that CCR2 is involved in a route to monolignols in Medicago whereby coniferaldehyde is formed via caffeyl aldehyde which then is 3-O-methylated by caffeic acid O-methyltransferase.	coniferaldehyde	95-110	CRINKLY4 related 2	Arabidopsis thaliana	32-36
20876124-7	2010	These observations suggest that CCR2 is involved in a route to monolignols in Medicago whereby coniferaldehyde is formed via caffeyl aldehyde which then is 3-O-methylated by caffeic acid O-methyltransferase.	Caffeic aldehyde	125-141	CRINKLY4 related 2	Arabidopsis thaliana	32-36
20876124-7	2010	These observations suggest that CCR2 is involved in a route to monolignols in Medicago whereby coniferaldehyde is formed via caffeyl aldehyde which then is 3-O-methylated by caffeic acid O-methyltransferase.	3-o	156-159	CRINKLY4 related 2	Arabidopsis thaliana	32-36