PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 35167730-0 2022 The MIEL1-ABI5/MYB30 regulatory module fine tunes abscisic acid signaling during seed germination. Abscisic Acid 50-63 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 4-9 28838126-6 2017 Genetic analysis reveals that wax accumulation of the miel1 mutant is compromised by myb96 or myb30 mutation, but MYB96 is mainly epistatic to MIEL1, playing a predominant role in cuticular wax deposition. Waxes 30-33 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 54-59 27615387-0 2016 The Arabidopsis MIEL1 E3 ligase negatively regulates ABA signalling by promoting protein turnover of MYB96. Abscisic Acid 53-56 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 16-21 27615387-3 2016 Here we show that the RING-type E3 ligase MYB30-INTERACTING E3 LIGASE 1 (MIEL1) regulates ABA sensitivity by promoting MYB96 turnover in Arabidopsis. Abscisic Acid 90-93 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 42-71 27615387-3 2016 Here we show that the RING-type E3 ligase MYB30-INTERACTING E3 LIGASE 1 (MIEL1) regulates ABA sensitivity by promoting MYB96 turnover in Arabidopsis. Abscisic Acid 90-93 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 73-78 27615387-4 2016 Germination of MIEL1-deficient mutant seeds is hypersensitive to ABA, whereas MIEL1-overexpressing transgenic seeds are less sensitive. Abscisic Acid 65-68 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 15-20 27615387-5 2016 MIEL1 can interact with MYB96, a regulator of ABA signalling, and stimulate its ubiquitination and degradation. Abscisic Acid 46-49 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 0-5 27615387-6 2016 Genetic analysis shows that MYB96 is epistatic to MIEL1 in the control of ABA sensitivity in seeds. Abscisic Acid 74-77 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 50-55 27615387-8 2016 We find that ABA regulates the expression of MYB30-responsive genes during pathogen infection and this regulation is partly dependent on MIEL1. Abscisic Acid 13-16 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 137-142 27615387-9 2016 These results suggest that MIEL1 may facilitate crosstalk between ABA and biotic stress signalling. Abscisic Acid 66-69 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 27-32 35167730-3 2022 Here, we report that the ubiquitin E3 ligase MIEL1 and its target transcription factor MYB30 modulate ABA responses in Arabidopsis thaliana during seed germination and seedling establishment via the precise regulation of ABI5. Abscisic Acid 102-105 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 45-50 35167730-7 2022 ABA treatment induces the degradation of MIEL1 and represses the interaction between MIEL1 and ABI5/MYB30, thus releasing both ABI5 and MYB30. Abscisic Acid 0-3 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 41-46 35167730-7 2022 ABA treatment induces the degradation of MIEL1 and represses the interaction between MIEL1 and ABI5/MYB30, thus releasing both ABI5 and MYB30. Abscisic Acid 0-3 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 85-90 35167730-8 2022 Our results demonstrate that MIEL1 directly mediates the proteasomal degradation of ABI5 and inhibits its activity via the release of its target protein MYB30, thus ensuring precise ABA signaling during seed germination and seedling establishment. Abscisic Acid 182-185 CHY-type/CTCHY-type/RING-type Zinc finger protein Arabidopsis thaliana 29-34