PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 2515762-1 1989 Calbindin 28K and calretinin are very similar calcium binding proteins which are both present in the central nervous system (CNS). Calcium 46-53 calbindin 2 Homo sapiens 18-28 13763469-0 1961 The concentration of I-131 in the bronchial tree after oral administration of tagged Cal-2 and KI. Iodine-131 21-26 calbindin 2 Homo sapiens 85-90 32890773-11 2020 By comparing several human control fetuses with a fetus chronically exposed to alcohol revealed that alcohol exposure led to mispositioning of the calretinin-positive interneurons, whose density was decreased in the superficial cortical layers II-III and increased in deepest layers. Alcohols 79-86 calbindin 2 Homo sapiens 147-157 32890773-11 2020 By comparing several human control fetuses with a fetus chronically exposed to alcohol revealed that alcohol exposure led to mispositioning of the calretinin-positive interneurons, whose density was decreased in the superficial cortical layers II-III and increased in deepest layers. Alcohols 101-108 calbindin 2 Homo sapiens 147-157 32972010-8 2020 Vitamin D in tissues or brain cells can also modulate calbindin-D28K, parvalbumin, and calretinin, and is involved in immune function, thanks also to the combination with curcumin. Vitamin D 0-9 calbindin 2 Homo sapiens 87-97 32565162-9 2020 Furthermore, miR-30b-3p exerted an inhibitory effect on odontoblast differentiation, which could be reversed by lncRNA CALB2. mir-30b-3p 13-23 calbindin 2 Homo sapiens 119-124 33897185-1 2020 Background: Calretinin is a calcium-binding protein of 29-kilodalton (kDa), which is widely expressed in normal human tissues and tumorigenic tissues. Calcium 28-35 calbindin 2 Homo sapiens 12-22 32350587-2 2020 PCP mechanisms are responsible for the organization of hair cell morphologic polarization vectors, and are thought to be responsible for the postsynaptic expression of the calcium-binding protein calretinin that defines the utricular striola and cristae central zone. Calcium 172-179 calbindin 2 Homo sapiens 196-206 31509615-0 2020 Serum calretinin as an independent predictor for platinum resistance and prognosis in ovarian cancer. Platinum 49-57 calbindin 2 Homo sapiens 6-16 31509615-1 2020 Calretinin (CRT) is a calcium-binding protein that controls intracellular calcium signaling. Calcium 22-29 calbindin 2 Homo sapiens 0-10 31509615-1 2020 Calretinin (CRT) is a calcium-binding protein that controls intracellular calcium signaling. Calcium 22-29 calbindin 2 Homo sapiens 12-15 31509615-1 2020 Calretinin (CRT) is a calcium-binding protein that controls intracellular calcium signaling. Calcium 74-81 calbindin 2 Homo sapiens 0-10 31509615-1 2020 Calretinin (CRT) is a calcium-binding protein that controls intracellular calcium signaling. Calcium 74-81 calbindin 2 Homo sapiens 12-15 31713514-3 2019 This study used an optogenetic approach to selectively activate spinal interneurons that express the calcium-binding protein calretinin (CR). Calcium 101-108 calbindin 2 Homo sapiens 125-135 32174951-9 2020 An in vitro Cd binding experiment revealed that CAL2 has Cd chelation activity. Cadmium 12-14 calbindin 2 Homo sapiens 48-52 32174951-9 2020 An in vitro Cd binding experiment revealed that CAL2 has Cd chelation activity. Cadmium 57-59 calbindin 2 Homo sapiens 48-52 31663141-2 2020 The well-known penta-atomic 18 valence electron (ve) species C Al 4 2 - and its Al- /Si or Al/Si+ isoelectronically replaced clusters CAl3 Si- , CAl2 Si2 , C AlSi 3 - , and C Si 4 2 + , all possess the same anti-van"t Hoff/Le Bel skeletons, that is, nontraditional planar tetracoordinate carbon (ptC) structure. Aluminum 61-65 calbindin 2 Homo sapiens 147-151 31663141-7 2020 Inclusion of chloride ion would further stabilize the ptC of CAl2 SiAl+ and CAl2 SiGa+ . Chlorides 13-21 calbindin 2 Homo sapiens 61-65 31663141-7 2020 Inclusion of chloride ion would further stabilize the ptC of CAl2 SiAl+ and CAl2 SiGa+ . Chlorides 13-21 calbindin 2 Homo sapiens 76-80 31663141-7 2020 Inclusion of chloride ion would further stabilize the ptC of CAl2 SiAl+ and CAl2 SiGa+ . leucite 66-70 calbindin 2 Homo sapiens 61-65 31663141-8 2020 The unexpectedly disclosed CAl2 SiAl+ and CAl2 SiGa+ represent the first type of 16ve-cationic ptCs with multiple bonds. leucite 32-36 calbindin 2 Homo sapiens 27-31 31052285-4 2019 In this review, we will summarize some of the evidence that expression of the EF-hand calcium-binding proteins, calbindin, calretinin and parvalbumin, may influence the susceptibility of distinct neuronal subpopulations to disease processes. Calcium 86-93 calbindin 2 Homo sapiens 123-133 31671889-0 2019 Modulation of Calretinin Expression in Human Mesothelioma Cells Reveals the Implication of the FAK and Wnt Signaling Pathways in Conferring Chemoresistance towards Cisplatin. Cisplatin 164-173 calbindin 2 Homo sapiens 14-24 31671889-3 2019 Calretinin is a Ca2+-binding protein expressed during MM tumorigenesis that activates the FAK signaling pathway, promoting invasion and epithelial-to-mesenchymal transition. Calcium 16-19 calbindin 2 Homo sapiens 0-10 31671889-5 2019 In order to evaluate early molecular events occurring during calretinin downregulation, we generated a tightly controlled IPTG-inducible expression system to modulate calretinin levels in vitro. Isopropyl Thiogalactoside 122-126 calbindin 2 Homo sapiens 61-71 31671889-5 2019 In order to evaluate early molecular events occurring during calretinin downregulation, we generated a tightly controlled IPTG-inducible expression system to modulate calretinin levels in vitro. Isopropyl Thiogalactoside 122-126 calbindin 2 Homo sapiens 167-177 30939888-1 2019 Histochemical diagnosis of Hirschsprung s disease at our institution was introduced in the 1970s, calretinin imunohistochemistry on formalin fixed tissue was newly added in 2015. Formaldehyde 132-140 calbindin 2 Homo sapiens 98-108 31081806-5 2019 Our novel protocol of immunostaining for calretinin, S100 protein, and protein gene product 9.5 (PGP9.5), which we conducted on RSBs, exhibits high sensitivity and specificity rates of 96.49% (95% confidence interval, 0.88-0.99) and 100% (95% confidence interval, 0.97-1.00), respectively. rsbs 128-132 calbindin 2 Homo sapiens 41-51 30460553-6 2019 Co-injection of the calb2a and calb2b morpholino oligonucleotide cocktail with human CALB2 mRNA leads to the rescue of the strong phenotype. Morpholinos 38-64 calbindin 2 Homo sapiens 85-90 30545133-1 2018 Calretinin (CR; CALB2) belonging to the family of EF-hand Ca2+-binding proteins (CaBP) is widely used as a positive marker for the identification of human malignant mesothelioma (MM) and functionally was suggested to play a critical role during carcinogenesis of this highly aggressive asbestos-associated neoplasm. Asbestos 286-294 calbindin 2 Homo sapiens 0-10 30545133-1 2018 Calretinin (CR; CALB2) belonging to the family of EF-hand Ca2+-binding proteins (CaBP) is widely used as a positive marker for the identification of human malignant mesothelioma (MM) and functionally was suggested to play a critical role during carcinogenesis of this highly aggressive asbestos-associated neoplasm. Asbestos 286-294 calbindin 2 Homo sapiens 12-14 30545133-1 2018 Calretinin (CR; CALB2) belonging to the family of EF-hand Ca2+-binding proteins (CaBP) is widely used as a positive marker for the identification of human malignant mesothelioma (MM) and functionally was suggested to play a critical role during carcinogenesis of this highly aggressive asbestos-associated neoplasm. Asbestos 286-294 calbindin 2 Homo sapiens 16-21 28508695-2 2018 At our institution, calretinin immunohistochemistry (CAL) is frequently requested by clinicians on rectal mucosal biopsies (RMBs) taken during colonoscopy in older children in whom suspicion for HD is low. rmbs 124-128 calbindin 2 Homo sapiens 20-30 29873281-6 2018 RESULTS: Nine of 10 (90%) cases of AR showed positive staining for inhibin and negative staining for calretinin, PAX2 and PAX8. Argon 35-37 calbindin 2 Homo sapiens 101-111 29510209-9 2018 VPA-exposed animals have reduced CB and CR immunolabeling and a lower density of dopaminergic terminals. Valproic Acid 0-3 calbindin 2 Homo sapiens 40-42 29534357-13 2018 Whereas GLUT1, calretinin and WT1 is the best for differential diagnosis between reactive mesothelium and mesothelioma in serous effusions. reactive mesothelium 81-101 calbindin 2 Homo sapiens 15-25 29417440-5 2018 Phenobarbital also reduced expression of neuronal markers (doublecortin (DCX), calretinin, NeuN), neuronal transcription factors (Pax6, Sox2, Tbr1/2, Prox1), and neurotrophins (NGF, BDNF, NT-3) up to 24 h after the last administration. Phenobarbital 0-13 calbindin 2 Homo sapiens 79-89 28544176-3 2017 We hypothesized that polymorphisms in five calcium-regulating genes (SLC8A1, ATP2B1, CALB1, CALB2, and CABP1) interact with calcium intake in relation to the risk of colorectal neoplasia. Calcium 43-50 calbindin 2 Homo sapiens 92-97 28544176-3 2017 We hypothesized that polymorphisms in five calcium-regulating genes (SLC8A1, ATP2B1, CALB1, CALB2, and CABP1) interact with calcium intake in relation to the risk of colorectal neoplasia. Calcium 124-131 calbindin 2 Homo sapiens 92-97 27990638-5 2017 Calcium homeostasis and signaling rely on many calcium-binding proteins including calretinin, of the "EF-hand" protein family. Calcium 0-7 calbindin 2 Homo sapiens 82-92 27990638-5 2017 Calcium homeostasis and signaling rely on many calcium-binding proteins including calretinin, of the "EF-hand" protein family. Calcium 47-54 calbindin 2 Homo sapiens 82-92 28849877-5 2017 Separate groups of neurons differ in the content of neuronal calcium-binding proteins, such as calbindin, calretinin and parvalbumin and neurofilaments: low molecular weight, a medium molecular weight and high molecular weight. Calcium 61-68 calbindin 2 Homo sapiens 106-116 28174028-1 2017 The immunohistochemical expression of the calcium-binding protein calretinin during human cerebellar development has been investigated in this study. Calcium 42-49 calbindin 2 Homo sapiens 66-76 28174028-9 2017 Moreover, given the critical role of calcium in a great variety of neuronal processes in the central nervous system, our findings suggest that calretinin may play a pivotal role in the regulation of neuronal excitability during intrauterine cerebellar development. Calcium 37-44 calbindin 2 Homo sapiens 143-153 27670960-1 2016 BACKGROUND: The study investigates the diagnostic value of calretinin immunohistochemical staining (CIS) on rectal suction biopsies (RSB) in Hirschsprung"s disease (HD). (1S,5S,6R)-10-(benzo[d]thiazol-6-ylsulfonyl)-5-(methoxymethyl)-3-(pyridin-2-ylethyl)-3,10-diazabicyclo[4.3.1]decan-2-one 133-136 calbindin 2 Homo sapiens 59-69 28042835-6 2016 According to the photoluminescence (PL) intensities spectra, the solubility parameters of PMMA and polyvinyl acetate (PVAc) are 9.19 cal1/2cm-3/2 and 9.85 cal1/2cm-3/2, respectively. Polymethyl Methacrylate 90-94 calbindin 2 Homo sapiens 133-151 28042835-6 2016 According to the photoluminescence (PL) intensities spectra, the solubility parameters of PMMA and polyvinyl acetate (PVAc) are 9.19 cal1/2cm-3/2 and 9.85 cal1/2cm-3/2, respectively. polyvinyl acetate 99-116 calbindin 2 Homo sapiens 133-151 28042835-6 2016 According to the photoluminescence (PL) intensities spectra, the solubility parameters of PMMA and polyvinyl acetate (PVAc) are 9.19 cal1/2cm-3/2 and 9.85 cal1/2cm-3/2, respectively. polyvinyl acetate 118-122 calbindin 2 Homo sapiens 133-151 28617379-7 2017 Calcium-binding proteins calbindin and calretinin were not found in the majority of nigral cells although calbindin was rarely seen in some neurons of the dorsal part and calretinin in the ventral one. Calcium 0-7 calbindin 2 Homo sapiens 39-49 27369965-5 2016 Calretinin (C) is a calcium-binding protein, expressed in the nervous system. Calcium 20-27 calbindin 2 Homo sapiens 0-10 28855933-11 2016 CONCLUSION: Calretinin IHC overcomes most of the difficulties encountered using the histology hematoxylin-eosin. Hematoxylin 94-105 calbindin 2 Homo sapiens 12-22 28855933-11 2016 CONCLUSION: Calretinin IHC overcomes most of the difficulties encountered using the histology hematoxylin-eosin. Eosine Yellowish-(YS) 106-111 calbindin 2 Homo sapiens 12-22 28514541-1 2016 Calbindin 28 kDa (CB), calretinin (CR) and parvalbumin (PB) are belonged to calcium-binding proteins which are widely distributed in the nervous system and selectively expressed in certain population of neurons. Calcium 76-83 calbindin 2 Homo sapiens 23-33 25824535-0 2016 GABA-Synthesizing Enzymes in Calbindin and Calretinin Neurons in Monkey Prefrontal Cortex. gamma-Aminobutyric Acid 0-4 calbindin 2 Homo sapiens 43-53 25824535-9 2016 These findings suggest that GABA synthesis from CB/GAD67+ and CR/GAD67+ neurons would presumably be more vulnerable to disease-associated deficits in GAD67 expression, such as in schizophrenia, than neurons that also contain GAD65. gamma-Aminobutyric Acid 28-32 calbindin 2 Homo sapiens 62-64 26536416-0 2016 Immunocytochemical localization of the calcium-binding proteins calbindin D28K, calretinin, and parvalbumin in bat visual cortex. Calcium 39-46 calbindin 2 Homo sapiens 80-90 25633096-1 2016 Recently, the Na(+)/Ca(+2) exchanger NCX1 and the calcium binding protein calretinin have emerged as new molecular effectors of delayed preconditioning in the brain. Calcium 50-57 calbindin 2 Homo sapiens 74-84 25633096-7 2016 Collectively, our results indicate that the Na(+)/Ca(+2) exchanger NCX1 and the calcium binding protein calretinin cooperate within the striatum to confer tolerance against cerebral ischemia. Calcium 80-87 calbindin 2 Homo sapiens 104-114 28514541-1 2016 Calbindin 28 kDa (CB), calretinin (CR) and parvalbumin (PB) are belonged to calcium-binding proteins which are widely distributed in the nervous system and selectively expressed in certain population of neurons. Calcium 76-83 calbindin 2 Homo sapiens 35-37 26202929-0 2016 A new monoclonal antibody (CAL2) detects CALRETICULIN mutations in formalin-fixed and paraffin-embedded bone marrow biopsies. Formaldehyde 67-75 calbindin 2 Homo sapiens 27-31 26202929-0 2016 A new monoclonal antibody (CAL2) detects CALRETICULIN mutations in formalin-fixed and paraffin-embedded bone marrow biopsies. Paraffin 86-94 calbindin 2 Homo sapiens 27-31 24185118-1 2014 Calretinin is a member of the EF-hand family of calcium-binding proteins. Calcium 48-55 calbindin 2 Homo sapiens 0-10 25324731-2 2014 CR is a calcium-binding protein expressed mainly by GABAergic interneurons in the hippocampus. Calcium 8-15 calbindin 2 Homo sapiens 0-2 25404384-9 2014 We found that the calcium-binding protein calretinin (CR) is dynamically expressed in L5a excitatory pyramidal neurons of the barrel cortex, and L5a neurons form a unique serrated pattern similar to the distributions of their presynaptic POm axon terminals. Calcium 18-25 calbindin 2 Homo sapiens 42-52 25404384-9 2014 We found that the calcium-binding protein calretinin (CR) is dynamically expressed in L5a excitatory pyramidal neurons of the barrel cortex, and L5a neurons form a unique serrated pattern similar to the distributions of their presynaptic POm axon terminals. Calcium 18-25 calbindin 2 Homo sapiens 54-56 25237298-1 2014 Calretinin is a calcium-binding protein often used as a marker for a subset of inhibitory interneurons in the mammalian neocortex. Calcium 16-23 calbindin 2 Homo sapiens 0-10 25320408-9 2014 Double-immunofluorescence revealed that the percentage of co-localization with GABA-IR cells was 0.0, 0.0, and 10.27% of CB-, CR-, and PV-IR cells, respectively. gamma-Aminobutyric Acid 79-83 calbindin 2 Homo sapiens 126-128 25118725-14 2014 CONCLUSION: Calretinin is a reliable single immune marker for ruling out HD by its specific positive mucosal staining of formalin fixed rectal biopsy. Formaldehyde 121-129 calbindin 2 Homo sapiens 12-22 24583405-6 2014 We found that treatment with ghrelin increased the number of doublecortin, HH3, and calretinin-stained cells in the hippocampus of 5XFAD mice. Ghrelin 29-36 calbindin 2 Homo sapiens 84-94 24917793-5 2014 At CS 21, the "pioneer cortical plate" appears as a radial aggregation of CR+/Tbr1+ neurons, which cover the entire future neocortex and extend the first corticofugal axons. Cesium 3-5 calbindin 2 Homo sapiens 74-76 24917793-10 2014 At CS 21-23, the CR+ SVZ at the PSB is the source of CR+ interneurons migrating into the cortical SVZ. Cesium 3-5 calbindin 2 Homo sapiens 17-19 24917793-10 2014 At CS 21-23, the CR+ SVZ at the PSB is the source of CR+ interneurons migrating into the cortical SVZ. Cesium 3-5 calbindin 2 Homo sapiens 53-55 24262018-1 2013 Calretinin, a calcium-binding protein, is a widely used marker for mesothelial differentiation. Calcium 14-21 calbindin 2 Homo sapiens 0-10 24412512-7 2014 In addition, vinpocetine prevented the loss of calretinin and parvalbumin immunoreactivity following ischaemia suggesting it may indirectly regulate intracellular calcium. vinpocetine 13-24 calbindin 2 Homo sapiens 47-57 24839578-2 2014 Calretinin is a 29 kDa calcium-binding protein of the EF-hand family which is expressed in a variety of normal and tumorigenic tissues. Calcium 23-30 calbindin 2 Homo sapiens 0-10 23649874-10 2013 PC-12 cells incubated in peritoneal fluids of women with endometriosis expressed less calretinin but more calbindin than the control group. PC 12 ester 0-5 calbindin 2 Homo sapiens 86-96 24453443-2 2013 The objective of this study was to determine calretinin expression in heamatoxylin and eosin diagnosed cases of ameloblastoma and non-neoplastic odontogenic cysts. heamatoxylin 70-82 calbindin 2 Homo sapiens 45-55 24453443-2 2013 The objective of this study was to determine calretinin expression in heamatoxylin and eosin diagnosed cases of ameloblastoma and non-neoplastic odontogenic cysts. Eosine Yellowish-(YS) 87-92 calbindin 2 Homo sapiens 45-55 23179862-9 2013 We identified regions within the cytoarchitectonically defined medial vestibular nucleus visualized by immunoreactivity to the calcium-binding proteins calretinin and calbindin as previously shown in other species including human. Calcium 127-134 calbindin 2 Homo sapiens 152-162 23772398-2 2013 By a proteomics-based approach, we compared an SCLC cell line with its CD9 transfectant and found that a calcium-binding neuronal protein, calretinin, is upregulated in CD9-positive SCLC cells. Calcium 105-112 calbindin 2 Homo sapiens 139-149 23595591-3 2013 CR protects against asbestos-induced acute cytotoxicity mediated by the AKT/PI3K pathway, and furthermore, SV40 early region genes are able to upregulate CR in mesothelial cells. Asbestos 20-28 calbindin 2 Homo sapiens 0-2 23595591-3 2013 CR protects against asbestos-induced acute cytotoxicity mediated by the AKT/PI3K pathway, and furthermore, SV40 early region genes are able to upregulate CR in mesothelial cells. Asbestos 20-28 calbindin 2 Homo sapiens 154-156 23696443-6 2013 Double-immunofluorescence labeling revealed that CR-positive terminals lacked the gamma-aminobutyric acid (GABA)-synthesizing enzyme glutamate decarboxylase, which is present in inhibitory afferents to all motoneurons mediating vertical eye movements. gamma-Aminobutyric Acid 107-111 calbindin 2 Homo sapiens 49-51 24094966-10 2013 Immunohistochemical staining for calretinin using paraffin-embedded tissue sections after cryostat sections clearly demonstrated decreased staining intensity compared to MAP-2. Paraffin 50-58 calbindin 2 Homo sapiens 33-43 24066870-1 2013 UNLABELLED: A 34-year-old female, with a history of continued asbestos exposure, presented with a papillary peritoneal mesothelioma with a diffuse, prominent clear foamy cell change, with microvacuolation in its papillary lining, that expressed cytokeratins 7, 5/6 and calretinin as well as nuclear WT-1 and apical membrane staining for thrombomodulin, podoplanin D2-40 and HBME-1. Asbestos 62-70 calbindin 2 Homo sapiens 269-279 23933500-5 2013 The calcium binding protein calretinin (CR) is expressed heavily in mossy fibres terminating throughout the cerebellar cortex, but whether CR is heterogeneously expressed in parasagittal stripes, like ZII, is unknown. Calcium 4-11 calbindin 2 Homo sapiens 28-38 23933500-5 2013 The calcium binding protein calretinin (CR) is expressed heavily in mossy fibres terminating throughout the cerebellar cortex, but whether CR is heterogeneously expressed in parasagittal stripes, like ZII, is unknown. Calcium 4-11 calbindin 2 Homo sapiens 40-42 23696443-3 2013 Recent work in monkey revealed that a subpopulation of premotor neurons of the vertical eye movement system contains the calcium-binding protein calretinin (CR). Calcium 121-128 calbindin 2 Homo sapiens 145-155 23696443-3 2013 Recent work in monkey revealed that a subpopulation of premotor neurons of the vertical eye movement system contains the calcium-binding protein calretinin (CR). Calcium 121-128 calbindin 2 Homo sapiens 157-159 23696443-6 2013 Double-immunofluorescence labeling revealed that CR-positive terminals lacked the gamma-aminobutyric acid (GABA)-synthesizing enzyme glutamate decarboxylase, which is present in inhibitory afferents to all motoneurons mediating vertical eye movements. gamma-Aminobutyric Acid 82-105 calbindin 2 Homo sapiens 49-51 23683882-6 2013 The results on calretinin were in good agreement with AChE according to the kappa index (0.946; P<.001) and presented significantly higher specificity (96.7x63.3; P<.002) and accuracy (97.6x74.4; P<.003) when compared with conventional histology (H&E). Adenosine Monophosphate 258-261 calbindin 2 Homo sapiens 15-25 23798809-4 2013 Calretinin processing was done on the paraffin-embedded blocks after routine histopathological examination. Paraffin 38-46 calbindin 2 Homo sapiens 0-10 23033479-3 2012 Here, we show that calretinin (CR), a Ca(2+)-binding protein highly expressed in subpopulations of neurons in the brain, inhibits CDI and enhances CDF by binding directly to alpha(1)2.1. 4-AMINO-1-{5-O-[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]-ALPHA-D-ARABINOFURANOSYL}PYRIMIDIN-2(1H)-ONE 147-150 calbindin 2 Homo sapiens 19-29 23841354-4 2013 In the considered nitrobenzene medium, it was found that the stability constants of the complexes CaL2(2+), CaL3(2+) and CaL4(2+), where L is DPPMDO, are somewhat higher than those of the corresponding complex species SrL2(2+), SrL3(2+) and SrL4(2+) with the same ligand L. nitrobenzene 18-30 calbindin 2 Homo sapiens 98-102 23841354-4 2013 In the considered nitrobenzene medium, it was found that the stability constants of the complexes CaL2(2+), CaL3(2+) and CaL4(2+), where L is DPPMDO, are somewhat higher than those of the corresponding complex species SrL2(2+), SrL3(2+) and SrL4(2+) with the same ligand L. dppmdo 142-148 calbindin 2 Homo sapiens 98-102 23841354-4 2013 In the considered nitrobenzene medium, it was found that the stability constants of the complexes CaL2(2+), CaL3(2+) and CaL4(2+), where L is DPPMDO, are somewhat higher than those of the corresponding complex species SrL2(2+), SrL3(2+) and SrL4(2+) with the same ligand L. srl4 241-245 calbindin 2 Homo sapiens 98-102 23202791-6 2013 The epithelial component of the PRMC showed positive staining for cytokeratin (CK) 7, CK AE1/3, epithelial membrane antigen, carcinoembryonic antigen, and calretinin. prmc 32-36 calbindin 2 Homo sapiens 89-165 23033479-3 2012 Here, we show that calretinin (CR), a Ca(2+)-binding protein highly expressed in subpopulations of neurons in the brain, inhibits CDI and enhances CDF by binding directly to alpha(1)2.1. 4-AMINO-1-{5-O-[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]-ALPHA-D-ARABINOFURANOSYL}PYRIMIDIN-2(1H)-ONE 147-150 calbindin 2 Homo sapiens 31-33 23033479-7 2012 In HEK293T cells, CR significantly decreased Ca(v)2.1 CDI and increased CDF. 4-AMINO-1-{5-O-[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]-ALPHA-D-ARABINOFURANOSYL}PYRIMIDIN-2(1H)-ONE 72-75 calbindin 2 Homo sapiens 18-20 23033479-8 2012 CR binding to alpha(1)2.1 was required for these effects, because they were not observed upon substitution of the II-III linker of alpha(1)2.1 with that from the Ca(v)1.2 alpha(1) subunit (alpha(1)1.2), which lacks the CRBs. crisamicin B 219-223 calbindin 2 Homo sapiens 0-2 22668856-0 2012 Prenatal dexamethasone selectively decreases calretinin expression in the adult female lateral amygdala. Dexamethasone 9-22 calbindin 2 Homo sapiens 45-55 22531174-1 2012 Calretinin is an intracellular calcium-binding EF-hand protein of the calmodulin superfamily. Calcium 31-38 calbindin 2 Homo sapiens 0-10 22891683-3 2012 To identify novel therapeutic targets, we recently employed the approach of tandem affinity purification and discovered that calretinin (Cr), a member of the EF-hand family of calcium-binding proteins, is preferentially associated with mHtt, although it also interacts with wild-type Htt. Calcium 176-183 calbindin 2 Homo sapiens 125-135 22891683-3 2012 To identify novel therapeutic targets, we recently employed the approach of tandem affinity purification and discovered that calretinin (Cr), a member of the EF-hand family of calcium-binding proteins, is preferentially associated with mHtt, although it also interacts with wild-type Htt. Calcium 176-183 calbindin 2 Homo sapiens 137-139 22891683-4 2012 These observations were supported by coimmunoprecipitation and by colocalization of Cr with mHtt in neuronal cultures. mhtt 92-96 calbindin 2 Homo sapiens 84-86 22891683-5 2012 Over- expression of Cr reduced mHtt-caused cytotoxicity in both non-neuronal and neuronal cell models of HD, whereas knockdown of Cr expression in the cells enhanced mHtt-caused neuronal cell death. mhtt 31-35 calbindin 2 Homo sapiens 20-22 22891683-5 2012 Over- expression of Cr reduced mHtt-caused cytotoxicity in both non-neuronal and neuronal cell models of HD, whereas knockdown of Cr expression in the cells enhanced mHtt-caused neuronal cell death. mhtt 166-170 calbindin 2 Homo sapiens 130-132 22891683-6 2012 In addition, over-expression of Cr was also associated with reduction of intracellular free calcium and activation of Akt. Calcium 92-99 calbindin 2 Homo sapiens 32-34 22668856-3 2012 Therefore, in the present study we investigated the effects of prenatal treatment with the glucocorticoid receptor agonist dexamethasone (DEX) on expression of calbindin and calretinin in brain areas critical to emotional regulation (basolateral/lateral amygdala and hippocampal CA1 and CA3 regions). Dexamethasone 123-136 calbindin 2 Homo sapiens 174-184 22668856-3 2012 Therefore, in the present study we investigated the effects of prenatal treatment with the glucocorticoid receptor agonist dexamethasone (DEX) on expression of calbindin and calretinin in brain areas critical to emotional regulation (basolateral/lateral amygdala and hippocampal CA1 and CA3 regions). Dexamethasone 138-141 calbindin 2 Homo sapiens 174-184 22668856-4 2012 Late gestational treatment with DEX (gestational days 18-22) significantly decreased the density of calretinin immunoreactive cells in the lateral amygdala of adult female offspring with no differences in the basolateral amygdala, hippocampal CA1, or CA3 regions. Dexamethasone 32-35 calbindin 2 Homo sapiens 100-110 22668856-7 2012 Together these findings indicate that late gestational DEX treatment causes a targeted reduction of calretinin within the lateral amygdala of females and this may be one mechanism through which developmental glucocorticoid exposure contributes to lasting alterations in emotional behavior. Dexamethasone 55-58 calbindin 2 Homo sapiens 100-110 21394464-1 2012 Calretinin is thought to be the main endogenous calcium buffer in cerebellar granule cells (GrCs). Calcium 48-55 calbindin 2 Homo sapiens 0-10 24061262-2 2012 Further, the stability constant of the electroneutral complex species CaL2 in water-saturated nitrobenzene was calculated for a temperature of 25 C : log betanb (CaL2) = 11.0 +- 0.2. water-saturated nitrobenzene 78-106 calbindin 2 Homo sapiens 70-74 24061262-2 2012 Further, the stability constant of the electroneutral complex species CaL2 in water-saturated nitrobenzene was calculated for a temperature of 25 C : log betanb (CaL2) = 11.0 +- 0.2. water-saturated nitrobenzene 78-106 calbindin 2 Homo sapiens 163-167 24061262-2 2012 Further, the stability constant of the electroneutral complex species CaL2 in water-saturated nitrobenzene was calculated for a temperature of 25 C : log betanb (CaL2) = 11.0 +- 0.2. betanb 155-161 calbindin 2 Homo sapiens 70-74 24061262-2 2012 Further, the stability constant of the electroneutral complex species CaL2 in water-saturated nitrobenzene was calculated for a temperature of 25 C : log betanb (CaL2) = 11.0 +- 0.2. betanb 155-161 calbindin 2 Homo sapiens 163-167 22343111-1 2012 Calretinin is a calcium-binding protein member of the EF-hand family. Calcium 16-23 calbindin 2 Homo sapiens 0-10 22798111-5 2012 RESULTS: Immunohistochemistry for calretinin provided highly compatible results with hematoxylin-eosin findings in Hirschsprung"s disease and non-Hirschsprung"s disease patients, except in one Hirschsprung"s disease patient with very rare nerve stainings at the distal surgical margin. Hematoxylin 85-96 calbindin 2 Homo sapiens 34-44 21226980-2 2011 Subgroups of GABA interneurons exert differential inhibitory control on principal pyramidal neurons and can be identified based on the non-overlapping expression of the calcium-binding proteins parvalbumin (PV) or calretinin (CR) or the neuropeptide somatostatin (SST). gamma-Aminobutyric Acid 13-17 calbindin 2 Homo sapiens 214-224 22272358-3 2012 Among them, GABAergic interneurons are the most abundant, and can be sorted in three populations according to their content in the calcium binding proteins calretinin (CR), parvalbumin (PV) and calbindin (CB). Calcium 131-138 calbindin 2 Homo sapiens 156-166 22020045-10 2011 CONCLUSIONS: Calretinin appears to be a useful marker to distinguish ONBs from other SRBCTs of the sinonasal tract, particularly when staining is moderate/strong and extensive. onbs 69-73 calbindin 2 Homo sapiens 13-23 23023339-4 2012 The aim of our study was to analyze the expression of calcium-binding proteins (calbindin, calretinin, parvalbumin) in cortical neurons of the cerebellum in patients diagnosed with Alzheimer"s disease (experimental group) and in a control group (patients without Alzheimer"s disease). Calcium 54-61 calbindin 2 Homo sapiens 91-101 21226980-2 2011 Subgroups of GABA interneurons exert differential inhibitory control on principal pyramidal neurons and can be identified based on the non-overlapping expression of the calcium-binding proteins parvalbumin (PV) or calretinin (CR) or the neuropeptide somatostatin (SST). gamma-Aminobutyric Acid 13-17 calbindin 2 Homo sapiens 226-228 21044398-4 2011 This study therefore examined immunohistochemically two calcium-binding proteins, calretinin and parvalbumin, which have been demonstrated to bind to two distinct GABAergic interneuron subpopulations, within the dorsolateral prefrontal cortex (DLPFC) of elderly depressed patients, against age-matched controls. Calcium 56-63 calbindin 2 Homo sapiens 82-92 21600703-5 2011 The tumor cells were positive for calretinin with strong nuclear and cytoplasmic expression together with podoplanin (D2-40) and some cytokeratins, but were negative for hepatocyte paraffin 1 and other adenocarcinoma markers. podoplanin 106-116 calbindin 2 Homo sapiens 34-44 21325508-5 2011 CalR(+) and GABA(+) cells were apparent for the first time after 3 d in vitro, and their number increased in subsequent days, consistent with the gradual transition of RG cells into CalR(+) or GABA(+) cells. gamma-Aminobutyric Acid 193-197 calbindin 2 Homo sapiens 0-4 21629658-0 2011 Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway. Fluorouracil 30-44 calbindin 2 Homo sapiens 0-11 21629658-4 2011 Further investigation revealed that CALB2 translocated to the mitochondria following 5-FU treatment and that 5-FU-induced loss of mitochondrial membrane potential (Deltapsi(m)) was abrogated in CALB2-silenced cells. Fluorouracil 109-113 calbindin 2 Homo sapiens 194-199 21629658-0 2011 Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway. Fluorouracil 30-44 calbindin 2 Homo sapiens 13-18 21629658-5 2011 Furthermore, CALB2 silencing decreased 5-FU-induced cytochrome c and smac release from the mitochondria and also decreased 5-FU-induced activation of caspases 9 and 3/7. Fluorouracil 39-43 calbindin 2 Homo sapiens 13-18 21629658-5 2011 Furthermore, CALB2 silencing decreased 5-FU-induced cytochrome c and smac release from the mitochondria and also decreased 5-FU-induced activation of caspases 9 and 3/7. Fluorouracil 123-127 calbindin 2 Homo sapiens 13-18 21629658-6 2011 Of note, co-silencing of XIAP overcame 5-FU resistance in CALB2-silenced cells. Fluorouracil 39-43 calbindin 2 Homo sapiens 58-63 21629658-7 2011 Collectively, these results suggest that following 5-FU treatment in CRC cell lines, CALB2 is involved in apoptosis induction through the intrinsic mitochondrial pathway. Fluorouracil 51-55 calbindin 2 Homo sapiens 85-90 21629658-8 2011 This indicates that CALB2 may be an important mediator of 5-FU-induced cell death. Fluorouracil 58-62 calbindin 2 Homo sapiens 20-25 21629658-9 2011 Moreover, down-regulation of CALB2 in response to 5-FU may represent an intrinsic mechanism of resistance to this anti-cancer drug. Fluorouracil 50-54 calbindin 2 Homo sapiens 29-34 21629658-1 2011 The role of the calcium binding protein, Calbindin 2 (CALB2), in regulating the response of colorectal cancer (CRC) cells to 5-Fluorouracil (5-FU) was investigated. Calcium 16-23 calbindin 2 Homo sapiens 41-52 21629658-1 2011 The role of the calcium binding protein, Calbindin 2 (CALB2), in regulating the response of colorectal cancer (CRC) cells to 5-Fluorouracil (5-FU) was investigated. Calcium 16-23 calbindin 2 Homo sapiens 54-59 21629658-1 2011 The role of the calcium binding protein, Calbindin 2 (CALB2), in regulating the response of colorectal cancer (CRC) cells to 5-Fluorouracil (5-FU) was investigated. Fluorouracil 125-139 calbindin 2 Homo sapiens 41-52 21629658-1 2011 The role of the calcium binding protein, Calbindin 2 (CALB2), in regulating the response of colorectal cancer (CRC) cells to 5-Fluorouracil (5-FU) was investigated. Fluorouracil 125-139 calbindin 2 Homo sapiens 54-59 21629658-1 2011 The role of the calcium binding protein, Calbindin 2 (CALB2), in regulating the response of colorectal cancer (CRC) cells to 5-Fluorouracil (5-FU) was investigated. Fluorouracil 141-145 calbindin 2 Homo sapiens 41-52 21629658-1 2011 The role of the calcium binding protein, Calbindin 2 (CALB2), in regulating the response of colorectal cancer (CRC) cells to 5-Fluorouracil (5-FU) was investigated. Fluorouracil 141-145 calbindin 2 Homo sapiens 54-59 21629658-2 2011 Real-time RT-PCR and Western blot analysis revealed that CALB2 mRNA and protein expression were down-regulated in p53 wild-type and p53 null isogenic HCT116 CRC cell lines following 48 h and 72 h 5-FU treatment. Fluorouracil 196-200 calbindin 2 Homo sapiens 57-62 21629658-3 2011 Moreover, 5-FU-induced apoptosis was significantly reduced in HCT116 and LS174T CRC cell lines in which CALB2 expression had been silenced. Fluorouracil 10-14 calbindin 2 Homo sapiens 104-109 21629658-4 2011 Further investigation revealed that CALB2 translocated to the mitochondria following 5-FU treatment and that 5-FU-induced loss of mitochondrial membrane potential (Deltapsi(m)) was abrogated in CALB2-silenced cells. Fluorouracil 85-89 calbindin 2 Homo sapiens 36-41 21629658-4 2011 Further investigation revealed that CALB2 translocated to the mitochondria following 5-FU treatment and that 5-FU-induced loss of mitochondrial membrane potential (Deltapsi(m)) was abrogated in CALB2-silenced cells. Fluorouracil 85-89 calbindin 2 Homo sapiens 194-199 21629658-4 2011 Further investigation revealed that CALB2 translocated to the mitochondria following 5-FU treatment and that 5-FU-induced loss of mitochondrial membrane potential (Deltapsi(m)) was abrogated in CALB2-silenced cells. Fluorouracil 109-113 calbindin 2 Homo sapiens 36-41 20715566-1 2010 Immunoreactivity of the calcium binging protein calretinin is often used as a marker of olfactory neurons. Calcium 24-31 calbindin 2 Homo sapiens 48-58 19830430-5 2010 We would like to report on a case of PMAC with the special feature of positive calretinin immunohistochemical staining. Phenylmercuric Acetate 37-41 calbindin 2 Homo sapiens 79-89 20509881-7 2010 Stability of spiked-in calretinin in EDTA plasma under different storage conditions was also examined. Edetic Acid 37-41 calbindin 2 Homo sapiens 23-33 20509881-11 2010 Recovery rate experiments confirmed dependence of calretinin antibody recognition on calcium concentration. Calcium 85-92 calbindin 2 Homo sapiens 50-60 20509881-12 2010 Calcium adjustment is necessary for calretinin measurement in EDTA plasma. Calcium 0-7 calbindin 2 Homo sapiens 36-46 20509881-12 2010 Calcium adjustment is necessary for calretinin measurement in EDTA plasma. Edetic Acid 62-66 calbindin 2 Homo sapiens 36-46 20509881-13 2010 Spiked-in calretinin revealed high stability in EDTA plasma when stored at room temperature, 4 degrees C, or after repeated freeze/thaw cycles. Edetic Acid 48-52 calbindin 2 Homo sapiens 10-20 20509881-14 2010 Median calretinin values in healthy volunteers, asbestos workers, and MM patients were 0.20, 0.33, and 0.84 ng/ml, respectively (p < 0.0001 for healthy vs. MM, p = 0.0036 for healthy vs. asbestos-exposed, p < 0.0001 for asbestos-exposed vs. MM). Asbestos 48-56 calbindin 2 Homo sapiens 7-17 20406030-1 2010 In the mammalian neocortex, the calcium-binding protein calretinin is expressed in a subset of cortical interneurons. Calcium 32-39 calbindin 2 Homo sapiens 56-66 20217863-5 2010 All 11 differential spots showed reduced intensity in simvastatin-treated samples and were identified as adipocyte plasma membrane associated protein, enolase, calretinin, coronin 1a, f-actin capping protein alpha1, f-actin capping protein alpha2, heat shock cognate protein 71, malate dehydrogenase, n-myc downregulated gene 1, prohibitin 2, Rab GDP dissociation inhibitor, translationally controlled tumor protein and voltage dependent anion selective channel protein 1. Simvastatin 54-65 calbindin 2 Homo sapiens 160-170 19998412-0 2010 A bipartite butyrate-responsive element in the human calretinin (CALB2) promoter acts as a repressor in colon carcinoma cells but not in mesothelioma cells. Butyrates 12-20 calbindin 2 Homo sapiens 53-63 19998412-0 2010 A bipartite butyrate-responsive element in the human calretinin (CALB2) promoter acts as a repressor in colon carcinoma cells but not in mesothelioma cells. Butyrates 12-20 calbindin 2 Homo sapiens 65-70 19998412-5 2010 Since CALB2 is one of the genes negatively regulated by butyrate in colon cancer cells and butyrate decreases calretinin protein expression levels in those cells, we investigated whether expression is regulated via putative butyrate-responsive elements (BRE) in the human CALB2 promoter. Butyrates 56-64 calbindin 2 Homo sapiens 6-11 19998412-5 2010 Since CALB2 is one of the genes negatively regulated by butyrate in colon cancer cells and butyrate decreases calretinin protein expression levels in those cells, we investigated whether expression is regulated via putative butyrate-responsive elements (BRE) in the human CALB2 promoter. Butyrates 91-99 calbindin 2 Homo sapiens 110-120 19998412-5 2010 Since CALB2 is one of the genes negatively regulated by butyrate in colon cancer cells and butyrate decreases calretinin protein expression levels in those cells, we investigated whether expression is regulated via putative butyrate-responsive elements (BRE) in the human CALB2 promoter. Butyrates 91-99 calbindin 2 Homo sapiens 110-120 19998412-8 2010 Calretinin expression in colon cancer cells is negatively regulated by butyrate via a bipartite BRE flanking the TATA box and this may be linked to butyrate"s chemopreventive activity. Butyrates 71-79 calbindin 2 Homo sapiens 0-10 19998412-8 2010 Calretinin expression in colon cancer cells is negatively regulated by butyrate via a bipartite BRE flanking the TATA box and this may be linked to butyrate"s chemopreventive activity. Butyrates 148-156 calbindin 2 Homo sapiens 0-10 19645526-7 2009 These changes include a decrease in the amount of parvalbumin (PV-IR) neurons in layer II, an increase of calbindin (CB-IR) neurons in layers III and V, and an increase in calretinin (CR-IR) neurons in layer II. Chromium 184-186 calbindin 2 Homo sapiens 172-182 19728992-3 2009 We have found that expression of the calcium-binding proteins calretinin (CR) and calbindin (CB), and the synthetic enzyme for nitric oxide synthase (nNOS) define subdivisions of the medial vestibular nucleus (MVe) and the nucleus prepositus (PrH), in cat, monkey, and human. Calcium 37-44 calbindin 2 Homo sapiens 62-72 19728992-3 2009 We have found that expression of the calcium-binding proteins calretinin (CR) and calbindin (CB), and the synthetic enzyme for nitric oxide synthase (nNOS) define subdivisions of the medial vestibular nucleus (MVe) and the nucleus prepositus (PrH), in cat, monkey, and human. Calcium 37-44 calbindin 2 Homo sapiens 74-76 19790285-8 2009 The calcium binding proteins calretinin and parvalbumin are found within the InM in partially overlapping populations. Calcium 4-11 calbindin 2 Homo sapiens 29-39 19435792-5 2009 Calretinin alone mediates a significant part of this protective effect because cells stably transfected with calretinin cDNA were clearly more resistant to the toxic effects of crocidolite than mock-transfected control cells. Asbestos, Crocidolite 177-188 calbindin 2 Homo sapiens 0-10 19435792-5 2009 Calretinin alone mediates a significant part of this protective effect because cells stably transfected with calretinin cDNA were clearly more resistant to the toxic effects of crocidolite than mock-transfected control cells. Asbestos, Crocidolite 177-188 calbindin 2 Homo sapiens 109-119 20163769-4 2009 In neocortical interneurons, GABA is also co-localized with calcium-binding proteins (parvalbumin, calbindin, calretinin), with neuropeptides and nitric oxide synthase. gamma-Aminobutyric Acid 29-33 calbindin 2 Homo sapiens 110-120 19028702-7 2009 Treatment with 3-keto-N-(aminoethyl-aminocaproyl-dihydrocinnamoyl)-cyclopamine induced cancer cell apoptosis, suppressed cell growth, mobility and invasiveness and induced cancer cell dedifferentiation with decreased expression of E-cadherin, cytokeratin 7, Snail, calretinin, vimentin, Bcl-2, caspases, beta1 integrin, MT1-MMP and VEGF. 3-keto-n-(aminoethyl-aminocaproyl-dihydrocinnamoyl)-cyclopamine 15-78 calbindin 2 Homo sapiens 265-275 18059437-2 2008 This study tested the hypothesis that PCP-induced developmental apoptosis causes a specific deficit of GABAergic interneurons containing parvalbumin (PV), calretinin (CR), or calbindin (CB). Phencyclidine 38-41 calbindin 2 Homo sapiens 155-165 18059437-2 2008 This study tested the hypothesis that PCP-induced developmental apoptosis causes a specific deficit of GABAergic interneurons containing parvalbumin (PV), calretinin (CR), or calbindin (CB). Phencyclidine 38-41 calbindin 2 Homo sapiens 167-169 18059437-4 2008 Further, CR and CB neurons, which were expressed at the time of PCP administration, showed no colocalization with cellular markers of apoptosis (terminal dUTP nick-end labeling (TUNEL) of broken DNA or cleaved caspase-3), indicating that CR- and CB-containing neurons were protected from the toxic effect of PCP and survived into adulthood. Phencyclidine 64-67 calbindin 2 Homo sapiens 9-11 18410500-6 2008 Both U0126 and the suppression of ERK1/2 expression with small interfering RNA effectively blocked the 4HPR-induced neuronal differentiation of RPE cells and the expression of calretinin. U 0126 5-10 calbindin 2 Homo sapiens 176-186 18558053-1 2008 BACKGROUND: Selective immunostaining for calretinin labels the innermost layer of the outer root sheath of normal hair follicles, which is difficult to distinguish with hematoxylin-eosin staining. Hematoxylin 169-180 calbindin 2 Homo sapiens 41-51 18558053-1 2008 BACKGROUND: Selective immunostaining for calretinin labels the innermost layer of the outer root sheath of normal hair follicles, which is difficult to distinguish with hematoxylin-eosin staining. Eosine Yellowish-(YS) 181-186 calbindin 2 Homo sapiens 41-51 16270201-5 2006 Based on these findings, we propose the following model of calcium secretion in human salivary glands: (1) calcium enters the acinar cell at the basolateral side via calcium channel CaT-Like (calcium influx); (2) intracellular calcium is taken up into the endoplasmic reticulum by SERCA-2 and possibly SERCA3 or bound to calbindin-2 (intracellular calcium pool); and (3) calcium is secreted by PMCAs at the apical plasma membrane (calcium efflux). Calcium 107-114 calbindin 2 Homo sapiens 321-332 18269580-1 2008 AIMS: Calretinin, a calcium-binding protein, is expressed primarily in certain subtypes of neurons. Calcium 20-27 calbindin 2 Homo sapiens 6-16 16270201-5 2006 Based on these findings, we propose the following model of calcium secretion in human salivary glands: (1) calcium enters the acinar cell at the basolateral side via calcium channel CaT-Like (calcium influx); (2) intracellular calcium is taken up into the endoplasmic reticulum by SERCA-2 and possibly SERCA3 or bound to calbindin-2 (intracellular calcium pool); and (3) calcium is secreted by PMCAs at the apical plasma membrane (calcium efflux). Calcium 59-66 calbindin 2 Homo sapiens 321-332 18266860-5 2008 Immunohistochemical analysis showed the inner epithelial layer of the cysts was positive with calretinin.With curettage and CO2 laser therapy, a good cosmetic result was achieved.This is the first case report in the German literature of a rare sporadic form of steatocystoma multiplex with late onset and exclusive localization in the face. N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide 124-127 calbindin 2 Homo sapiens 94-104 18361442-1 2008 Different subclasses of gamma-aminobutyric acid (GABA) cortical neurons can be distinguished by their content of neuropeptides such as somatostatin (SST), or calcium-binding proteins such as calretinin (CR). gamma-Aminobutyric Acid 24-47 calbindin 2 Homo sapiens 191-201 18361442-1 2008 Different subclasses of gamma-aminobutyric acid (GABA) cortical neurons can be distinguished by their content of neuropeptides such as somatostatin (SST), or calcium-binding proteins such as calretinin (CR). gamma-Aminobutyric Acid 49-53 calbindin 2 Homo sapiens 191-201 18361442-1 2008 Different subclasses of gamma-aminobutyric acid (GABA) cortical neurons can be distinguished by their content of neuropeptides such as somatostatin (SST), or calcium-binding proteins such as calretinin (CR). Calcium 158-165 calbindin 2 Homo sapiens 191-201 18297277-1 2008 Parvalbumin (PV) and calretinin (CR) are calcium binding proteins (CBP"s) expressed in discrete GABAergic interneuron populations in the human cortex. Calcium 41-48 calbindin 2 Homo sapiens 21-31 18297277-1 2008 Parvalbumin (PV) and calretinin (CR) are calcium binding proteins (CBP"s) expressed in discrete GABAergic interneuron populations in the human cortex. Calcium 41-48 calbindin 2 Homo sapiens 33-35 18297277-6 2008 Modifications in interneuron parvalbumin or calretinin levels could change calcium buffering capacity, as well as the way these cells respond to neuronal insults. Calcium 75-82 calbindin 2 Homo sapiens 44-54 18044987-14 2007 The Ca2+ binding to calretinin was assessed by measuring the decay of free Ca2+ using a fast fluorescent Ca2+ indicator following rapid (<50-mus rise time) Ca2+ concentration jumps induced by uncaging Ca2+ from DM-nitrophen. DM-nitrophen 214-226 calbindin 2 Homo sapiens 20-30 17188660-6 2007 The close correspondence of blotting analysis, immunocytochemistry and in situ hybridization indicates with no doubt that calretinin, like other calcium-binding proteins previously studied, is also present in the nervous system of cephalopods. Calcium 145-152 calbindin 2 Homo sapiens 122-132 17188660-7 2007 Furthermore, although recent findings localize calretinin also in endocrine glands, the presence of this calcium-binding protein in the brain of octopus indicates that calretinin appeared early in the phylogeny as a neuronal protein already in invertebrates. Calcium 105-112 calbindin 2 Homo sapiens 168-178 16270201-5 2006 Based on these findings, we propose the following model of calcium secretion in human salivary glands: (1) calcium enters the acinar cell at the basolateral side via calcium channel CaT-Like (calcium influx); (2) intracellular calcium is taken up into the endoplasmic reticulum by SERCA-2 and possibly SERCA3 or bound to calbindin-2 (intracellular calcium pool); and (3) calcium is secreted by PMCAs at the apical plasma membrane (calcium efflux). Calcium 107-114 calbindin 2 Homo sapiens 321-332 16270201-5 2006 Based on these findings, we propose the following model of calcium secretion in human salivary glands: (1) calcium enters the acinar cell at the basolateral side via calcium channel CaT-Like (calcium influx); (2) intracellular calcium is taken up into the endoplasmic reticulum by SERCA-2 and possibly SERCA3 or bound to calbindin-2 (intracellular calcium pool); and (3) calcium is secreted by PMCAs at the apical plasma membrane (calcium efflux). Calcium 107-114 calbindin 2 Homo sapiens 321-332 16270201-5 2006 Based on these findings, we propose the following model of calcium secretion in human salivary glands: (1) calcium enters the acinar cell at the basolateral side via calcium channel CaT-Like (calcium influx); (2) intracellular calcium is taken up into the endoplasmic reticulum by SERCA-2 and possibly SERCA3 or bound to calbindin-2 (intracellular calcium pool); and (3) calcium is secreted by PMCAs at the apical plasma membrane (calcium efflux). Calcium 107-114 calbindin 2 Homo sapiens 321-332 16270201-5 2006 Based on these findings, we propose the following model of calcium secretion in human salivary glands: (1) calcium enters the acinar cell at the basolateral side via calcium channel CaT-Like (calcium influx); (2) intracellular calcium is taken up into the endoplasmic reticulum by SERCA-2 and possibly SERCA3 or bound to calbindin-2 (intracellular calcium pool); and (3) calcium is secreted by PMCAs at the apical plasma membrane (calcium efflux). Calcium 107-114 calbindin 2 Homo sapiens 321-332 16270201-5 2006 Based on these findings, we propose the following model of calcium secretion in human salivary glands: (1) calcium enters the acinar cell at the basolateral side via calcium channel CaT-Like (calcium influx); (2) intracellular calcium is taken up into the endoplasmic reticulum by SERCA-2 and possibly SERCA3 or bound to calbindin-2 (intracellular calcium pool); and (3) calcium is secreted by PMCAs at the apical plasma membrane (calcium efflux). Calcium 107-114 calbindin 2 Homo sapiens 321-332 16902759-0 2005 The calcium binding proteins calbindin, parvalbumin, and calretinin have specific patterns of expression in the gray matter of cat spinal cord. Calcium 4-11 calbindin 2 Homo sapiens 57-67 15937279-1 2005 Calretinin, a neuronal protein with well-defined calcium-binding properties, has a poorly defined function. Calcium 49-56 calbindin 2 Homo sapiens 0-10 16338820-4 2005 Expression of calcium binding proteins, calretinin and calbindin-D28K, normally widely seen in dorsal horn interneurons, was up-regulated on the DCP-treated side. diphenylcyclopropenone 145-148 calbindin 2 Homo sapiens 40-50 15937279-3 2005 A drop in pH within the intracellular range (from pH 7.5 to pH 6.5) leads to an increased hydrophobicity of calcium-bound CR and its domains as reported by fluorescence spectroscopy with the hydrophobic probe 2-(p-toluidino)-6-naphthalenesulfonic acid (TNS). Calcium 108-115 calbindin 2 Homo sapiens 122-124 15937279-3 2005 A drop in pH within the intracellular range (from pH 7.5 to pH 6.5) leads to an increased hydrophobicity of calcium-bound CR and its domains as reported by fluorescence spectroscopy with the hydrophobic probe 2-(p-toluidino)-6-naphthalenesulfonic acid (TNS). 2-(4-toluidino)-6-naphthalenesulfonic acid 209-251 calbindin 2 Homo sapiens 122-124 15937279-3 2005 A drop in pH within the intracellular range (from pH 7.5 to pH 6.5) leads to an increased hydrophobicity of calcium-bound CR and its domains as reported by fluorescence spectroscopy with the hydrophobic probe 2-(p-toluidino)-6-naphthalenesulfonic acid (TNS). 2-(4-toluidino)-6-naphthalenesulfonic acid 253-256 calbindin 2 Homo sapiens 122-124 15937279-9 2005 CR may sense and respond to calcium, proton, and other signals, contributing to conflicting data on the proteins role as a calcium sensor or calcium buffer. Calcium 28-35 calbindin 2 Homo sapiens 0-2 15937279-9 2005 CR may sense and respond to calcium, proton, and other signals, contributing to conflicting data on the proteins role as a calcium sensor or calcium buffer. Calcium 123-130 calbindin 2 Homo sapiens 0-2 15937279-9 2005 CR may sense and respond to calcium, proton, and other signals, contributing to conflicting data on the proteins role as a calcium sensor or calcium buffer. Calcium 123-130 calbindin 2 Homo sapiens 0-2 15246702-7 2004 Other early committed neurons expressed the calcium-binding proteins calretinin (CR) or parvalbumin (PV). Calcium 44-51 calbindin 2 Homo sapiens 69-79 15739785-4 2005 UBN synthesize glutamate, calretinin, and metabotropic and ionotropic glutamate receptors. 4-methyl-~{N}-[(~{E})-oct-5-enyl]piperidine-1-carboxamide 0-3 calbindin 2 Homo sapiens 26-36 15297969-7 2004 OSE with a cuboidal morphology had a similar immunoreactivity as omental peritoneum, expressing calretinin, mesothelin, and CD9. serine O-sulfate 0-3 calbindin 2 Homo sapiens 96-106 15561434-2 2005 Different subclasses of GABA-containing neurons can be distinguished by their content of the calcium-binding proteins parvalbumin (PV) and calretinin (CR). gamma-Aminobutyric Acid 24-28 calbindin 2 Homo sapiens 139-149 15561434-2 2005 Different subclasses of GABA-containing neurons can be distinguished by their content of the calcium-binding proteins parvalbumin (PV) and calretinin (CR). gamma-Aminobutyric Acid 24-28 calbindin 2 Homo sapiens 151-153 15561434-2 2005 Different subclasses of GABA-containing neurons can be distinguished by their content of the calcium-binding proteins parvalbumin (PV) and calretinin (CR). Calcium 93-100 calbindin 2 Homo sapiens 151-153 15246702-7 2004 Other early committed neurons expressed the calcium-binding proteins calretinin (CR) or parvalbumin (PV). Calcium 44-51 calbindin 2 Homo sapiens 81-83 14608532-1 2003 Calretinin is a calcium-binding protein expressed in different normal and neoplastic tissues. Calcium 16-23 calbindin 2 Homo sapiens 0-10 15220363-2 2004 A subclass of nerve cell bodies in both submucosa and myenteric ganglia of the human gastrointestinal tract were found to show immunopositivity for calretinin, a calcium binding protein, which plays an important role in the organisation and functioning of the central nervous system. Calcium 162-169 calbindin 2 Homo sapiens 148-158 12821392-1 2003 Calbindin-D(28k) (CB), calretinin (CRT), and parvalbumin (PV) are high-affinity cytosolic calcium (Ca(2+)) binding proteins (CBP) that have been found to regulate intracellular calcium concentrations in neurons through their buffering capacity and to protect neurons from insults that induce elevations of intracellular Ca(2+). Calcium 90-97 calbindin 2 Homo sapiens 23-33 12821392-1 2003 Calbindin-D(28k) (CB), calretinin (CRT), and parvalbumin (PV) are high-affinity cytosolic calcium (Ca(2+)) binding proteins (CBP) that have been found to regulate intracellular calcium concentrations in neurons through their buffering capacity and to protect neurons from insults that induce elevations of intracellular Ca(2+). Calcium 90-97 calbindin 2 Homo sapiens 35-38 12821392-1 2003 Calbindin-D(28k) (CB), calretinin (CRT), and parvalbumin (PV) are high-affinity cytosolic calcium (Ca(2+)) binding proteins (CBP) that have been found to regulate intracellular calcium concentrations in neurons through their buffering capacity and to protect neurons from insults that induce elevations of intracellular Ca(2+). Calcium 177-184 calbindin 2 Homo sapiens 23-33 12821392-1 2003 Calbindin-D(28k) (CB), calretinin (CRT), and parvalbumin (PV) are high-affinity cytosolic calcium (Ca(2+)) binding proteins (CBP) that have been found to regulate intracellular calcium concentrations in neurons through their buffering capacity and to protect neurons from insults that induce elevations of intracellular Ca(2+). Calcium 177-184 calbindin 2 Homo sapiens 35-38 14994582-4 2003 UBN synthesize glutamate, calretinin, contain metabo- and ionotropic glutamate receptors. 4-methyl-~{N}-[(~{E})-oct-5-enyl]piperidine-1-carboxamide 0-3 calbindin 2 Homo sapiens 26-36 12579997-2 2003 Calretinin, a calcium-binding protein related structurally to S-100, and inhibin, a polypeptide hormone secreted primarily by ovarian granulosa cells and testicular Sertoli cells and functioning as an inhibitor for pituitary follicle-stimulating hormone secretion, are potentially useful but not well-evaluated markers for GCTs. Calcium 14-21 calbindin 2 Homo sapiens 0-10 12372661-2 2002 The calcium-binding proteins parvalbumin, calbindin, and calretinin can be used as markers for specific subpopulations of cortical GABAergic interneurons. Calcium 4-11 calbindin 2 Homo sapiens 57-67 12879963-2 2002 Calretinin (CR), calbindin D-28k (CB) and parvalbumin (PV) belong to the large family of EF-hand calcium-binding proteins, which comprises more than 200 members in man. Calcium 97-104 calbindin 2 Homo sapiens 0-10 12879963-2 2002 Calretinin (CR), calbindin D-28k (CB) and parvalbumin (PV) belong to the large family of EF-hand calcium-binding proteins, which comprises more than 200 members in man. Calcium 97-104 calbindin 2 Homo sapiens 12-14 12493841-4 2003 The HSQC spectrum of (15)N-labeled CR is similar to the overlaid spectra of individual (15)N-labeled CR fragments (CR I-II and CR III-VI), also suggesting that these regions do not interact within intact CR. Nitrogen 25-26 calbindin 2 Homo sapiens 35-37 12493841-4 2003 The HSQC spectrum of (15)N-labeled CR is similar to the overlaid spectra of individual (15)N-labeled CR fragments (CR I-II and CR III-VI), also suggesting that these regions do not interact within intact CR. Nitrogen 91-92 calbindin 2 Homo sapiens 101-103 12493841-4 2003 The HSQC spectrum of (15)N-labeled CR is similar to the overlaid spectra of individual (15)N-labeled CR fragments (CR I-II and CR III-VI), also suggesting that these regions do not interact within intact CR. Nitrogen 91-92 calbindin 2 Homo sapiens 101-103 11849731-0 2002 Cell dynamics of calretinin-immunoreactive neurons in the rostral migratory stream after ibotenate-induced lesions in the forebrain. Ibotenic Acid 89-98 calbindin 2 Homo sapiens 17-27 12359331-1 2002 Calretinin (CR) is an EF-hand calcium binding protein expressed at high level in neurons. Calcium 30-37 calbindin 2 Homo sapiens 0-10 12359331-1 2002 Calretinin (CR) is an EF-hand calcium binding protein expressed at high level in neurons. Calcium 30-37 calbindin 2 Homo sapiens 12-14 12209836-4 2002 In all mammalian species so far examined, the vestibulocerebellum is enriched of UBCs that are strongly immunoreactive for the calcium binding protein calretinin (CR) in both the somatodendritic and axonal compartment. ubcs 81-85 calbindin 2 Homo sapiens 151-161 12209836-4 2002 In all mammalian species so far examined, the vestibulocerebellum is enriched of UBCs that are strongly immunoreactive for the calcium binding protein calretinin (CR) in both the somatodendritic and axonal compartment. ubcs 81-85 calbindin 2 Homo sapiens 163-165 12209836-4 2002 In all mammalian species so far examined, the vestibulocerebellum is enriched of UBCs that are strongly immunoreactive for the calcium binding protein calretinin (CR) in both the somatodendritic and axonal compartment. Calcium 127-134 calbindin 2 Homo sapiens 151-161 12209836-4 2002 In all mammalian species so far examined, the vestibulocerebellum is enriched of UBCs that are strongly immunoreactive for the calcium binding protein calretinin (CR) in both the somatodendritic and axonal compartment. Calcium 127-134 calbindin 2 Homo sapiens 163-165 12051635-5 2002 We evaluated calretinin reactivity in formalin-fixed, paraffin-embedded sections of 10 LCT, three SCT, five Leydig cell hyperplasia, two Sertoli cell adenomas, eight seminomatous tumors, five nonseminomatous germ cell tumors (mixed tumor), one adenomatoid tumor, and two normal testes using a standard immunohistochemical technique with a microwave-mediated epitope retrieval. Formaldehyde 38-46 calbindin 2 Homo sapiens 13-23 12051635-5 2002 We evaluated calretinin reactivity in formalin-fixed, paraffin-embedded sections of 10 LCT, three SCT, five Leydig cell hyperplasia, two Sertoli cell adenomas, eight seminomatous tumors, five nonseminomatous germ cell tumors (mixed tumor), one adenomatoid tumor, and two normal testes using a standard immunohistochemical technique with a microwave-mediated epitope retrieval. Paraffin 54-62 calbindin 2 Homo sapiens 13-23 11849731-5 2002 Two days after ibotenate injections, massive degeneration of calretinin (+) cells occurred in the RMS and its adjacent forebrains. Ibotenic Acid 15-24 calbindin 2 Homo sapiens 61-71 11849731-6 2002 Thereafter, calretinin (+) cells gradually increased in the RMS and reached above their control value 2 weeks after ibotenate injections. Ibotenic Acid 116-125 calbindin 2 Homo sapiens 12-22 11849731-8 2002 Autoradiographic experiments using (3)H-thymidine showed that calretinin (+) cells were continually generated in the RMS and underwent neuronal turnover within 8 weeks in a normal condition. h-thymidine 38-49 calbindin 2 Homo sapiens 62-72 11478931-4 2001 We tested, directly, the capacity of the three calcium-binding proteins calretinin (CR), calbindin D-28k (CB) and parvalbumin (PV) to buffer [Ca(2+)], and to protect cells against excitotoxic death. Calcium 47-54 calbindin 2 Homo sapiens 72-82 12236093-1 2002 Recent studies have demonstrated that antibodies against the calcium-binding proteins (CaBPs) parvalbumin (PV), calbindin (CB), and calretinin (CR) are appropriate tools for demonstrating transient features and developmental changes of human fetal brain organization as well as for detecting specific alterations in pathologically altered specimens. Calcium 61-68 calbindin 2 Homo sapiens 144-146 11478931-9 2001 CR- and CB-expressing cells were protected from death during the first 2 h of exposure to NMDA. N-Methylaspartate 90-94 calbindin 2 Homo sapiens 0-2 11438383-0 2001 An unusual population of pyramidal neurons in the anterior cingulate cortex of hominids contains the calcium-binding protein calretinin. Calcium 101-108 calbindin 2 Homo sapiens 125-135 11461122-0 2001 Calretinin and calretinin-22k increase resistance toward sodium butyrate-induced differentiation in CaCo-2 colon adenocarcinoma cells. Butyric Acid 57-72 calbindin 2 Homo sapiens 0-10 11461122-0 2001 Calretinin and calretinin-22k increase resistance toward sodium butyrate-induced differentiation in CaCo-2 colon adenocarcinoma cells. Butyric Acid 57-72 calbindin 2 Homo sapiens 15-25 11461122-5 2001 Down-regulation of calretinins in WiDr cells by antisense oligonucleotides leads to growth inhibition and treatment with sodium butyrate (NaBt, an inducer of differentiation) leads to a blockage of the cell cycle and, in parallel, to down-regulation of CR. Butyric Acid 121-136 calbindin 2 Homo sapiens 253-255 11461122-5 2001 Down-regulation of calretinins in WiDr cells by antisense oligonucleotides leads to growth inhibition and treatment with sodium butyrate (NaBt, an inducer of differentiation) leads to a blockage of the cell cycle and, in parallel, to down-regulation of CR. NABT 138-142 calbindin 2 Homo sapiens 253-255 11461122-8 2001 CR-22k was down-regulated in NaBt-treated cells and the normally cytoplasmic protein was preferentially localized in the nucleus either as a result of translocation or selective nuclear maintenance, a process more pronounced than in the case of CR. NABT 29-33 calbindin 2 Homo sapiens 0-2 11461122-11 2001 The CR-expressing clones were almost completely resistant to treatment with 0.5 mM NaBt, a concentration significantly reducing cell growth in control cells. NABT 83-87 calbindin 2 Homo sapiens 4-6 11218063-4 2001 This study is aimed at providing a detailed account of the distribution of three calcium-binding proteins: calretinin (CR), calbindin (CB), and parvalbumin (PV), which are known to be expressed in distinct neuronal populations. Calcium 81-88 calbindin 2 Homo sapiens 107-117 11318896-1 2001 AIMS: Calretinin, a 29-kDa calcium-binding protein is expressed widely in normal human tissues and tumours including both unicystic and solid and multicystic ameloblastomas. Calcium 27-34 calbindin 2 Homo sapiens 6-16 11218063-4 2001 This study is aimed at providing a detailed account of the distribution of three calcium-binding proteins: calretinin (CR), calbindin (CB), and parvalbumin (PV), which are known to be expressed in distinct neuronal populations. Calcium 81-88 calbindin 2 Homo sapiens 119-121 10942575-0 2000 Association between the calcium-binding protein calretinin and cytoskeletal components in the human colon adenocarcinoma cell line WiDr. Calcium 24-31 calbindin 2 Homo sapiens 48-58 10942575-4 2000 It has been shown previously that combined treatment with an inducer of differentiation sodium butyrate (NaBt) and a cell growth inhibitor hexamethylene bisacetamide (HMBA) or treatment with CR antisense oligonucleotides is down-regulating CR in parallel with a decrease of cell growth, suggesting a possible involvement of CR in maintaining the undifferentiated phenotype of WiDr cells. Butyric Acid 88-103 calbindin 2 Homo sapiens 240-242 11440160-0 2001 Cation binding properties of calretinin, an EF-hand calcium-binding protein. Calcium 52-59 calbindin 2 Homo sapiens 29-39 11440160-1 2001 Calretinin (CR) is a neuronal EF-hand protein previously characterized as a calcium (micromolar affinity) binding protein. Calcium 76-83 calbindin 2 Homo sapiens 0-10 11275783-2 2001 This study is aimed at investigating alterations of interneurons which can be immunolabelled by antibodies against the calcium-binding proteins calretinin (CR), calbindin (CB) and parvalbumin (PV). Calcium 119-126 calbindin 2 Homo sapiens 144-154 11275783-2 2001 This study is aimed at investigating alterations of interneurons which can be immunolabelled by antibodies against the calcium-binding proteins calretinin (CR), calbindin (CB) and parvalbumin (PV). Calcium 119-126 calbindin 2 Homo sapiens 156-158 10752489-3 2000 As an example of how this method can be used, teratocarcinoma cells were transfected with the neuron-specific calcium binding protein calretinin (CR) tagged with green fluorescent protein (GFP). Calcium 110-117 calbindin 2 Homo sapiens 134-144 10896333-3 2000 Calretinin, a calcium-binding protein, has been reported to be a selective marker for mesothelioma and largely is absent from adenocarcinoma on histologic material. Calcium 14-21 calbindin 2 Homo sapiens 0-10 10942575-4 2000 It has been shown previously that combined treatment with an inducer of differentiation sodium butyrate (NaBt) and a cell growth inhibitor hexamethylene bisacetamide (HMBA) or treatment with CR antisense oligonucleotides is down-regulating CR in parallel with a decrease of cell growth, suggesting a possible involvement of CR in maintaining the undifferentiated phenotype of WiDr cells. Butyric Acid 88-103 calbindin 2 Homo sapiens 240-242 10942575-4 2000 It has been shown previously that combined treatment with an inducer of differentiation sodium butyrate (NaBt) and a cell growth inhibitor hexamethylene bisacetamide (HMBA) or treatment with CR antisense oligonucleotides is down-regulating CR in parallel with a decrease of cell growth, suggesting a possible involvement of CR in maintaining the undifferentiated phenotype of WiDr cells. NABT 105-109 calbindin 2 Homo sapiens 240-242 10942575-4 2000 It has been shown previously that combined treatment with an inducer of differentiation sodium butyrate (NaBt) and a cell growth inhibitor hexamethylene bisacetamide (HMBA) or treatment with CR antisense oligonucleotides is down-regulating CR in parallel with a decrease of cell growth, suggesting a possible involvement of CR in maintaining the undifferentiated phenotype of WiDr cells. NABT 105-109 calbindin 2 Homo sapiens 240-242 10942575-4 2000 It has been shown previously that combined treatment with an inducer of differentiation sodium butyrate (NaBt) and a cell growth inhibitor hexamethylene bisacetamide (HMBA) or treatment with CR antisense oligonucleotides is down-regulating CR in parallel with a decrease of cell growth, suggesting a possible involvement of CR in maintaining the undifferentiated phenotype of WiDr cells. hexamethylene bisacetamide 139-165 calbindin 2 Homo sapiens 240-242 10942575-4 2000 It has been shown previously that combined treatment with an inducer of differentiation sodium butyrate (NaBt) and a cell growth inhibitor hexamethylene bisacetamide (HMBA) or treatment with CR antisense oligonucleotides is down-regulating CR in parallel with a decrease of cell growth, suggesting a possible involvement of CR in maintaining the undifferentiated phenotype of WiDr cells. hexamethylene bisacetamide 139-165 calbindin 2 Homo sapiens 240-242 10942575-4 2000 It has been shown previously that combined treatment with an inducer of differentiation sodium butyrate (NaBt) and a cell growth inhibitor hexamethylene bisacetamide (HMBA) or treatment with CR antisense oligonucleotides is down-regulating CR in parallel with a decrease of cell growth, suggesting a possible involvement of CR in maintaining the undifferentiated phenotype of WiDr cells. hexamethylene bisacetamide 167-171 calbindin 2 Homo sapiens 240-242 10942575-4 2000 It has been shown previously that combined treatment with an inducer of differentiation sodium butyrate (NaBt) and a cell growth inhibitor hexamethylene bisacetamide (HMBA) or treatment with CR antisense oligonucleotides is down-regulating CR in parallel with a decrease of cell growth, suggesting a possible involvement of CR in maintaining the undifferentiated phenotype of WiDr cells. hexamethylene bisacetamide 167-171 calbindin 2 Homo sapiens 240-242 10397400-5 1999 At midgestation, the calcium binding protein calretinin stained in the marginal zone numerous neurons, including the Cajal-Retzius cells and their processes. Calcium 21-28 calbindin 2 Homo sapiens 45-55 10614581-0 1999 Most calretinin-containing amacrine cells in the rabbit retina co-localize glycine. Glycine 75-82 calbindin 2 Homo sapiens 5-15 10614581-7 1999 Since calretinin-positive cells in the ganglion cell layer have been identified as ganglion cells based on soma size and presence of calretinin-positive axons in the optic nerve fiber layer, this population may represent a class of ganglion cell which contains glycine. Glycine 261-268 calbindin 2 Homo sapiens 6-16 10614581-9 1999 Rather, calretinin, just as other calcium-binding proteins, is distributed in a species-specific manner. Calcium 34-41 calbindin 2 Homo sapiens 8-18 10783640-9 1999 The sensitivity (100%) and specificity (100%) of reactivity for Calretinin and Ber-EP4 showed that the immunocytochemical results on paraffin embedded material from cavity effusions are very reliable, so that the tested immunocytochemical panel can be useful in cytological differential diagnosis between reactive mesothelial hyperplasia/mesothelioma and metastatic carcinoma. Paraffin 133-141 calbindin 2 Homo sapiens 64-74 10595711-0 1999 A polyclonal goat antiserum against the calcium-binding protein calretinin is a versatile tool for various immunochemical techniques. Calcium 40-47 calbindin 2 Homo sapiens 64-74 10441237-7 1999 Second, the percentage of CB-, CR-, and PV-ir neurons receiving multiple contacts on their somata and proximal dendrites from other calcium-binding protein neurons varied between 22% and 85%. Calcium 132-139 calbindin 2 Homo sapiens 31-33 10492135-1 1999 The pattern of distribution and colocalization of nitric oxide synthase and the calcium-binding protein calretinin in myenteric neurons and nerve fibers were examined in the human small intestine from preterm fetuses (14-17 weeks of gestation), normal adults (mean age 50 years old), old age (mean age 80 years old), and Crohn"s disease patients (mean age 30 years old) using NADPH-diaphorase histochemistry and immunohistochemical techniques. Calcium 80-87 calbindin 2 Homo sapiens 104-114 10402268-1 1999 The distribution patterns of the calcium-binding proteins calbindin and calretinin, both expressed early during development within the various amygdaloid nuclei and areas, have been investigated. Calcium 33-40 calbindin 2 Homo sapiens 72-82 10086235-5 1999 Calretinin is a calcium-binding protein within the family of EF-hand proteins. Calcium 16-23 calbindin 2 Homo sapiens 0-10 10215153-1 1999 Immunohistochemical studies have shown that the three calcium-binding proteins (calbindin-D28k, calretinin and parvalbumin) are heterogeneously distributed in the mammalian brain and are useful for delineating nuclear boundaries. Calcium 54-61 calbindin 2 Homo sapiens 96-106 10082975-0 1999 Measurements of [Ca2+] using fura-2 in glioma C6 cells expressing calretinin with GFP as a marker of transfection: no Ca2+-buffering provided by calretinin. Fura-2 29-35 calbindin 2 Homo sapiens 66-76 10086235-13 1999 Twenty-seven percent of RMC, 58% of MMs, and 31% of ACAs immunoreacted with anti-calretinin. rmc 24-27 calbindin 2 Homo sapiens 81-91 10223310-0 1999 Cellular distribution of the calcium-binding proteins parvalbumin, calbindin, and calretinin in the neocortex of mammals: phylogenetic and developmental patterns. Calcium 29-36 calbindin 2 Homo sapiens 82-92 10425647-1 1999 Calretinin (CR) is a 31.5 kDa EF-hand calcium binding protein. Calcium 38-45 calbindin 2 Homo sapiens 0-10 10425647-1 1999 Calretinin (CR) is a 31.5 kDa EF-hand calcium binding protein. Calcium 38-45 calbindin 2 Homo sapiens 12-14 10425647-4 1999 It is often postulated that the presence of CR correlates with an increased survival ability of cells under pathological conditions connected with increased intracellular calcium levels. Calcium 171-178 calbindin 2 Homo sapiens 44-46 10425647-6 1999 Recent results concerning CR function are discussed and the conclusion is proposed that CR acts as a calcium modulator rather than a calcium buffer. Calcium 101-108 calbindin 2 Homo sapiens 88-90 10223310-1 1999 The three calcium-binding proteins parvalbumin, calbindin, and calretinin are found in morphologically distinct classes of inhibitory interneurons as well as in some pyramidal neurons in the mammalian neocortex. Calcium 10-17 calbindin 2 Homo sapiens 63-73 9930892-5 1999 Horizontally oriented neurons in the molecular layer of the hippocampal formation have been visualized by antibodies against the calcium-binding proteins calretinin and calbindin D-28k. Calcium 129-136 calbindin 2 Homo sapiens 154-164 10336058-2 1999 A comparison is made of the cellular distribution of calretinin with two other calcium-binding proteins, calbindin and parvalbumin, recently reported by us in the human retina, and by parallel labeling with both antisera in the same tissues. Calcium 79-86 calbindin 2 Homo sapiens 53-63 10338273-1 1999 Among the dopaminergic neurons in substantia nigra pars compacta and in the ventral tegmental area, subpopulations express the calcium-binding proteins calbindin (CB) and calretinin (CR), and the CB-containing neurons are supposed to be less prone to degeneration in Parkinson"s disease. Calcium 127-134 calbindin 2 Homo sapiens 183-185 10197772-6 1999 Further, a marked heterogeneity was noted with regard to the expression of the messenger RNA"s encoding the three calcium-binding proteins; this elliptical nucleus was highly enriched in parvalbumin messenger RNA-positive neurons and calretinin mRNA-positive cells but not calbindin messenger RNA-positive cells. Calcium 114-121 calbindin 2 Homo sapiens 234-244 10340147-1 1999 WiDr cells from a human colon adenocarcinoma cultivated in vitro express the calcium binding protein calretinin. Calcium 77-84 calbindin 2 Homo sapiens 101-111 10340147-5 1999 The percentage of the calretinin immunoreactive cells increases after the addition of colchicine to the medium while the immunoblot analysis shows a higher calretinin content in the cells treated with taxol. Colchicine 86-96 calbindin 2 Homo sapiens 22-32 10340147-5 1999 The percentage of the calretinin immunoreactive cells increases after the addition of colchicine to the medium while the immunoblot analysis shows a higher calretinin content in the cells treated with taxol. Paclitaxel 201-206 calbindin 2 Homo sapiens 22-32 10340147-5 1999 The percentage of the calretinin immunoreactive cells increases after the addition of colchicine to the medium while the immunoblot analysis shows a higher calretinin content in the cells treated with taxol. Paclitaxel 201-206 calbindin 2 Homo sapiens 156-166 10197772-10 1999 The unique patterns of calcium-binding protein gene expression were similarly reflected at the protein level; an abundance of parvalbumin- and calretinin-immunopositive neurons were observed whereas only occasional intensely-labelled calbindin-immunopositive fibres were seen, no calbindin-immunopositive cells were detected. Calcium 23-30 calbindin 2 Homo sapiens 143-153 9450535-1 1998 An immunohistochemical approach was used to characterize the morphological phenotype of neurons containing the calcium-binding proteins calretinin (CR), parvalbumin (PV), or calbindin-D28k (CB) in the normal human striatum. Calcium 111-118 calbindin 2 Homo sapiens 136-146 9526028-1 1998 The localization and levels of expression of the calcium-binding protein calretinin (CR) in the human thalamus was studied with an in situ hybridization method applied to formalin-fixed postmortem material from normal individuals. Calcium 49-56 calbindin 2 Homo sapiens 73-83 9526028-1 1998 The localization and levels of expression of the calcium-binding protein calretinin (CR) in the human thalamus was studied with an in situ hybridization method applied to formalin-fixed postmortem material from normal individuals. Calcium 49-56 calbindin 2 Homo sapiens 85-87 9526028-1 1998 The localization and levels of expression of the calcium-binding protein calretinin (CR) in the human thalamus was studied with an in situ hybridization method applied to formalin-fixed postmortem material from normal individuals. Formaldehyde 171-179 calbindin 2 Homo sapiens 73-83 9526028-10 1998 The data also demonstrate that the presence of CR gene transcript can easily be detected on formalin-fixed sections of the human brain. Formaldehyde 92-100 calbindin 2 Homo sapiens 47-49 10430473-1 1999 We recently reported the existence of medium and large intemeurons immunoreactive for the calcium-binding protein calretinin in the human striatum. Calcium 90-97 calbindin 2 Homo sapiens 114-124 9776132-1 1998 We recently reported the existence of a new class of aspiny interneurons characterized by their immunoreactivity for the calcium-binding protein calretinin (CR) in human striatum. Calcium 121-128 calbindin 2 Homo sapiens 145-155 9539224-1 1998 The distribution of the calcium-binding protein calretinin in the thalamus of normal human individuals was studied with immunohistochemistry. Calcium 24-31 calbindin 2 Homo sapiens 48-58 9539224-10 1998 The pattern of distribution of calretinin, as delineated in the present study, suggests that this calcium-binding protein may participate in various subcortical and cortical thalamic systems involved in the modulation of emotional and motivational states. Calcium 98-105 calbindin 2 Homo sapiens 31-41 9509411-0 1997 Immunocytochemical localization of calcium-binding protein calretinin containing neurons in cat visual cortex. Calcium 35-42 calbindin 2 Homo sapiens 59-69 9452956-1 1998 Calretinin is a calcium-binding protein which is primarily expressed by certain cells of the nervous system, both central and peripheral. Calcium 16-23 calbindin 2 Homo sapiens 0-10 9842634-3 1998 Efficient results in histological differential diagnosis of malignant mesothelioma versus lung-adenocarcinoma applying a novel antiserum against the calcium binding protein calretinin inspirated us to investigate the value of anti-calretinin antibody in effusion cytology combined with an epithelial marker. Calcium 149-156 calbindin 2 Homo sapiens 173-183 9509411-8 1997 These results indicate that the calcium-binding protein calretinin is contained both in specific layers and selective cell types in the cat primary visual cortex. Calcium 32-39 calbindin 2 Homo sapiens 56-66 9412906-1 1997 We have examined the distribution of double bouquet cell axons, immunocytochemically stained for the calcium-binding proteins calretinin and calbindin D-28k in the human temporal neocortex, in relation to bundles of myelinated axons (originating from pyramidal cells) and the colocalization of these calcium-binding proteins. Calcium 101-108 calbindin 2 Homo sapiens 126-136 9368033-6 1997 Limited proteolysis and thiol reactivity suggest that that the C terminus of full-length CR, but not of CR-22k, is in close proximity of site I leading to mutual shielding. Sulfhydryl Compounds 24-29 calbindin 2 Homo sapiens 89-91 9368033-8 1997 The optical properties are very similar for CR-22k and CR, even though CR-22k possesses one additional Trp at the C-terminal end, and revealed that the Trp residues are organized into a hydrophobic core in the metal-free proteins and become even better shielded from the aqueous environment upon binding of Ca2+. Tryptophan 152-155 calbindin 2 Homo sapiens 44-46 9364239-1 1997 Parvalbumin, calretinin, and calbindin-D28k are calcium-binding proteins that are located in largely nonoverlapping neuronal populations in the brain. Calcium 48-55 calbindin 2 Homo sapiens 13-23 9390137-2 1997 OBJECTIVE: To document that a polyclonal antiserum to calretinin, a 29-kd calcium-binding protein, consistently decorates normal and tumor mesothelial cells in cytologic preparations. Calcium 74-81 calbindin 2 Homo sapiens 54-64 9136798-1 1997 The calcium-binding protein calretinin (CR) is present in a subpopulation of local-circuit neurons in the mammalian cerebral cortex containing gamma-aminobutyric acid. gamma-Aminobutyric Acid 143-166 calbindin 2 Homo sapiens 28-38 9185552-1 1997 Previous immunocytochemical studies in the cerebral cortex of various species have shown that the calcium-binding protein calretinin (CR) labels specific subpopulations of nonspiny nonpyramidal cells (interneurons). Calcium 98-105 calbindin 2 Homo sapiens 122-132 9185552-1 1997 Previous immunocytochemical studies in the cerebral cortex of various species have shown that the calcium-binding protein calretinin (CR) labels specific subpopulations of nonspiny nonpyramidal cells (interneurons). Calcium 98-105 calbindin 2 Homo sapiens 134-136 9136798-1 1997 The calcium-binding protein calretinin (CR) is present in a subpopulation of local-circuit neurons in the mammalian cerebral cortex containing gamma-aminobutyric acid. gamma-Aminobutyric Acid 143-166 calbindin 2 Homo sapiens 40-42 9147483-0 1997 Calretinin in the cat retina: colocalizations with other calcium-binding proteins, GABA and glycine. Calcium 57-64 calbindin 2 Homo sapiens 0-10 16465248-1 1997 The calcium-binding protein calretinin and the alternatively spliced form calretinin-22k are expressed in the colon adenocarcinoma cell line WiDr. Calcium 4-11 calbindin 2 Homo sapiens 28-38 16465248-3 1997 The addition of 1,25-dihydroxy vitamin D3 (10(-8) M) led to a transient translocation of calretinin-22k into the nucleus, while the cell growth was not affected. Calcitriol 16-41 calbindin 2 Homo sapiens 89-99 16465248-4 1997 The addition of sodium butyrate and hexamethylene bisacteamide which induce markers of enterocyte differentiation decreased the levels of both forms of calretinin more than 90%. Butyric Acid 16-31 calbindin 2 Homo sapiens 152-162 16465248-4 1997 The addition of sodium butyrate and hexamethylene bisacteamide which induce markers of enterocyte differentiation decreased the levels of both forms of calretinin more than 90%. hexamethylene bisacteamide 36-62 calbindin 2 Homo sapiens 152-162 9147483-12 1997 The possibility remains that calretinin and other calcium-binding proteins may play a role in neurotransmission through interactions with receptors or second-messenger agents. Calcium 50-57 calbindin 2 Homo sapiens 29-39 9147483-0 1997 Calretinin in the cat retina: colocalizations with other calcium-binding proteins, GABA and glycine. gamma-Aminobutyric Acid 83-87 calbindin 2 Homo sapiens 0-10 9147483-0 1997 Calretinin in the cat retina: colocalizations with other calcium-binding proteins, GABA and glycine. Glycine 92-99 calbindin 2 Homo sapiens 0-10 9147483-1 1997 Immunocytochemical techniques were used to determine the distribution of the calcium-binding protein calretinin in the cat retina. Calcium 77-84 calbindin 2 Homo sapiens 101-111 8864572-1 1996 An alternatively spliced mRNA for the calcium-binding protein calretinin (CR) is present in the colon adenocarcinoma cell line WiDr. Calcium 38-45 calbindin 2 Homo sapiens 62-72 8898855-4 1996 Treatment of HT29-18 cells with galactose led to a drop in the calretinin mRNA level and in protein expression as evidenced by immunocytochemical staining and Western blot analysis of cytosolic cell extracts. Galactose 32-41 calbindin 2 Homo sapiens 63-73 8896701-1 1996 Calretinin is an "EF-hand" calcium-binding protein involved in the maintenance of intracellular calcium ion homeostasis. Calcium 27-34 calbindin 2 Homo sapiens 0-10 8885200-22 1996 The complex temporal developmental patterns found in this study suggested that viewing PV, CaB, and CaR simply as calcium-buffering proteins severely underestimates their functional roles during visual system maturation. Calcium 114-121 calbindin 2 Homo sapiens 100-103 9042211-0 1996 Heterogeneity of expression of the calcium-binding protein calretinin in human colonic cancer cell lines. Calcium 35-42 calbindin 2 Homo sapiens 59-69 9042211-2 1996 We were able to demonstrate that calretinin is expressed in the cell lines HT-29, WiDr, LoVo, LS180, CO112, CO115. co112 101-106 calbindin 2 Homo sapiens 33-43 9042211-2 1996 We were able to demonstrate that calretinin is expressed in the cell lines HT-29, WiDr, LoVo, LS180, CO112, CO115. co115 108-113 calbindin 2 Homo sapiens 33-43 8914086-2 1996 We recently reported the existence of a new class of interneurons characterized by their immunoreactivity for the calcium-binding protein calretinin in the human striatum. Calcium 114-121 calbindin 2 Homo sapiens 138-148 8864572-1 1996 An alternatively spliced mRNA for the calcium-binding protein calretinin (CR) is present in the colon adenocarcinoma cell line WiDr. Calcium 38-45 calbindin 2 Homo sapiens 74-76 8743426-2 1996 Double labeling immunocytochemical studies of CalB, CalR, and GABA in experimental animals have shown that CalB and CalR are present in separate subpopulations of neurons. gamma-Aminobutyric Acid 62-66 calbindin 2 Homo sapiens 116-120 8841885-1 1996 Neurofilament protein and calcium-binding proteins parvalbumin, calbindin, and calretinin are present in morphologically distinct neuronal subpopulations in the mammalian cerebral cortex. Calcium 26-33 calbindin 2 Homo sapiens 79-89 8743426-7 1996 A relatively large proportion of CalB- and CalR-immunoreactive cells (approximately 71% and 74%, respectively) were found to be immunoreactive for GABA. gamma-Aminobutyric Acid 147-151 calbindin 2 Homo sapiens 43-47 8692714-0 1996 The calcium binding protein calretinin is a selective marker for malignant pleural mesotheliomas of the epithelial type. Calcium 4-11 calbindin 2 Homo sapiens 28-38 8660929-3 1996 Treatment of WiDr cells with phosphorothioate antisense oligodeoxynucleotides (AS-ODNs) led to a drop in calretinin expression, as evidenced by immunohistochemical staining of WiDr cells and Western blot analysis of cytosolic cell extracts. Parathion 29-45 calbindin 2 Homo sapiens 105-115 8660929-3 1996 Treatment of WiDr cells with phosphorothioate antisense oligodeoxynucleotides (AS-ODNs) led to a drop in calretinin expression, as evidenced by immunohistochemical staining of WiDr cells and Western blot analysis of cytosolic cell extracts. Oligodeoxyribonucleotides 56-77 calbindin 2 Homo sapiens 105-115 8660929-3 1996 Treatment of WiDr cells with phosphorothioate antisense oligodeoxynucleotides (AS-ODNs) led to a drop in calretinin expression, as evidenced by immunohistochemical staining of WiDr cells and Western blot analysis of cytosolic cell extracts. as-odns 79-86 calbindin 2 Homo sapiens 105-115 8720880-1 1996 Neurons immunoreactive for the calcium-binding protein calretinin (CR) were visualized in the substantia nigra (SN) pars compacta (SNc), reticulata (SNr) and lateralis (SNl), the ventral tegmental area (VTA) and the subthalamic nucleus (STN) of squirrel monkeys. Calcium 31-38 calbindin 2 Homo sapiens 55-65 8720880-1 1996 Neurons immunoreactive for the calcium-binding protein calretinin (CR) were visualized in the substantia nigra (SN) pars compacta (SNc), reticulata (SNr) and lateralis (SNl), the ventral tegmental area (VTA) and the subthalamic nucleus (STN) of squirrel monkeys. Calcium 31-38 calbindin 2 Homo sapiens 67-69 8592150-4 1996 Calretinin, calbindin D28k, and parvalbumin incubated in high calcium were recognized by antisera better than when they were incubated in low calcium. Calcium 62-69 calbindin 2 Homo sapiens 0-10 8592150-4 1996 Calretinin, calbindin D28k, and parvalbumin incubated in high calcium were recognized by antisera better than when they were incubated in low calcium. Calcium 142-149 calbindin 2 Homo sapiens 0-10 8592150-7 1996 The calretinin antiserum appeared to recognize a portion of the molecule previously shown to undergo calcium-dependent conformational changes. Calcium 101-108 calbindin 2 Homo sapiens 4-14 8592150-8 1996 A calcium-insensitive antiserum was made to a different fragment of calretinin. Calcium 2-9 calbindin 2 Homo sapiens 68-78 8852935-11 1996 This finding adds to the hypothesis that in pinealocytes of some species calretinin plays a role in calcium-mediated signal transduction which eventually is linked to melatonin synthesis. Calcium 100-107 calbindin 2 Homo sapiens 73-83 8872563-12 1996 Calretinin may be involved in signal processing in the cerebellum, perhaps regulating the amount and form of intracellular calcium. Calcium 123-130 calbindin 2 Homo sapiens 0-10 8821449-3 1996 Cortical interneurons were identified immunocytochemically by the expression of the calcium binding proteins calretinin (CR), parvalbumin (PV) and calbindin D-28k (CB). Calcium 84-91 calbindin 2 Homo sapiens 109-119 8852935-11 1996 This finding adds to the hypothesis that in pinealocytes of some species calretinin plays a role in calcium-mediated signal transduction which eventually is linked to melatonin synthesis. Melatonin 167-176 calbindin 2 Homo sapiens 73-83 8682939-1 1995 The development of the calcium-binding protein calretinin (CaR) and its co-localization with GABA was studied in the striate cortex of Macaca monkeys from fetal day (Fd) 45 to adult. Calcium 23-30 calbindin 2 Homo sapiens 47-57 8682939-13 1995 CaR-immunoreactivity is colocalized with GABA in almost all CaR+ cells with the exception of Cajal-Retzius cells in the MZ and some large cells observed at Fd70-101 in the VZ. gamma-Aminobutyric Acid 41-45 calbindin 2 Homo sapiens 0-3 8682939-14 1995 The band of CaR+ fibers in the IZ is GABA-. gamma-Aminobutyric Acid 37-41 calbindin 2 Homo sapiens 12-15 8682939-1 1995 The development of the calcium-binding protein calretinin (CaR) and its co-localization with GABA was studied in the striate cortex of Macaca monkeys from fetal day (Fd) 45 to adult. Calcium 23-30 calbindin 2 Homo sapiens 59-62 8682939-15 1995 At Fd90, almost all (> 96%) CaR+ cells are GABA+ in the CP and the first developed layers V/VI. gamma-Aminobutyric Acid 46-50 calbindin 2 Homo sapiens 31-34 8550898-3 1995 AII cells of the monkey retina were stained immunocytochemically with antibodies against the calcium-binding protein calretinin. Calcium 93-100 calbindin 2 Homo sapiens 117-127 8682939-16 1995 This percentage declines later, so that on average 80% of CaR+ cells are GABA+ in adult cortex. gamma-Aminobutyric Acid 73-77 calbindin 2 Homo sapiens 58-61 8682939-17 1995 At Fd135, 53% of GABA+ neurons located in layers II/III are CaR+; this percentage declines to 37% in the adult. gamma-Aminobutyric Acid 17-21 calbindin 2 Homo sapiens 60-63 8682939-18 1995 These double-label patterns suggest that early in fetal development the majority of GABA+ cells stain for CaR and that expression of CaR may be related to the migration of these neurons into the cortical plate. gamma-Aminobutyric Acid 84-88 calbindin 2 Homo sapiens 106-109 8682939-19 1995 Once they attain their final position in the cortex many GABA+ cells loose CaR-immunoreactivity, so that in postnatal life only a minority of GABA+ neurons contain this calcium-binding protein. gamma-Aminobutyric Acid 57-61 calbindin 2 Homo sapiens 75-78 8576712-1 1995 This paper reports a double-labelling immunocytochemical study of the three calcium-binding proteins calretinin, parvalbumin, and calbindin-D28k in developing and adult Macaca primary visual cortex. Calcium 76-83 calbindin 2 Homo sapiens 101-111 8557843-11 1995 These colocalizations of calcium-binding proteins in the CRc differed from the other nonpyramidal cortical neurons where calbindin, calretinin, and parvalbumin are contained in different (mutually exclusive) neuronal populations. Calcium 25-32 calbindin 2 Homo sapiens 132-142 7865754-2 1994 At variance with this idea is the present finding that calretinin (CR), a calcium binding protein, occurs only in a subset of pallidal neurones in squirrel monkeys. Calcium 74-81 calbindin 2 Homo sapiens 55-65 7607211-1 1995 cDNA clones for calretinin, a member of the troponin-C family of calcium-binding proteins, were isolated from a cDNA library of the human colon carcinoma cell line WiDr. Calcium 65-72 calbindin 2 Homo sapiens 16-26 7607211-6 1995 The truncated proteins were able to bind calcium, as evidenced by a calcium blot of the delta 8 form (calretinin-20k) and delta 8,9 form (calretinin-22k) expressed in Escherichia coli. Calcium 41-48 calbindin 2 Homo sapiens 102-112 7607211-6 1995 The truncated proteins were able to bind calcium, as evidenced by a calcium blot of the delta 8 form (calretinin-20k) and delta 8,9 form (calretinin-22k) expressed in Escherichia coli. Calcium 41-48 calbindin 2 Homo sapiens 138-148 7796115-1 1995 The human striatum contains two types of neurons displaying immunoreactivity for the calcium-binding protein calretinin (CR): (1) large (22, 44 microns>), multipolar neurons with 5-7 long, aspiny and tightly branched dendrites, and (2) medium-sized (9-18 microns), round-to-oval neurons with 2-3 long, varicose and poorly branched dendrites. Calcium 85-92 calbindin 2 Homo sapiens 109-119 7704619-0 1994 Does the calcium binding protein calretinin protect dopaminergic neurons against degeneration in Parkinson"s disease? Calcium 9-16 calbindin 2 Homo sapiens 33-43 7891886-1 1994 In squirrel monkeys, the calcium-binding protein calretinin (CR) was found to be distributed according to strikingly different patterns in striatal patch/matrix compartments, as visualized on adjacent sections immunostained for another calcium-binding protein, calbindin D-28k. Calcium 236-243 calbindin 2 Homo sapiens 49-59 7891886-1 1994 In squirrel monkeys, the calcium-binding protein calretinin (CR) was found to be distributed according to strikingly different patterns in striatal patch/matrix compartments, as visualized on adjacent sections immunostained for another calcium-binding protein, calbindin D-28k. Calcium 236-243 calbindin 2 Homo sapiens 61-63 7743217-2 1995 We report that cultured hippocampal neurons exhibiting immunoreactivity for the calcium binding protein calretinin are relatively resistant to degeneration resulting from exposure to either beta 25-35 or beta 1-42. Calcium 80-87 calbindin 2 Homo sapiens 104-114 7743217-3 1995 These findings suggest that intrinsic characteristics of calretinin cells, possibly including enhanced calcium buffering capacity, underlie the resistance of these cells to A beta toxicity in vitro and perhaps similar insults in Alzheimer"s disease. Calcium 103-110 calbindin 2 Homo sapiens 57-67 7891886-1 1994 In squirrel monkeys, the calcium-binding protein calretinin (CR) was found to be distributed according to strikingly different patterns in striatal patch/matrix compartments, as visualized on adjacent sections immunostained for another calcium-binding protein, calbindin D-28k. Calcium 25-32 calbindin 2 Homo sapiens 49-59 7891886-1 1994 In squirrel monkeys, the calcium-binding protein calretinin (CR) was found to be distributed according to strikingly different patterns in striatal patch/matrix compartments, as visualized on adjacent sections immunostained for another calcium-binding protein, calbindin D-28k. Calcium 25-32 calbindin 2 Homo sapiens 61-63 7865754-2 1994 At variance with this idea is the present finding that calretinin (CR), a calcium binding protein, occurs only in a subset of pallidal neurones in squirrel monkeys. Calcium 74-81 calbindin 2 Homo sapiens 67-69 8201027-1 1994 In the subcortical auditory system of Rhinolophus rouxi, antibodies directed against the calcium-binding proteins parvalbumin, calbindin D-28k, and calretinin yield partly overlapping and partly complementary labeling patterns which are described in detail for each nucleus. Calcium 89-96 calbindin 2 Homo sapiens 148-158 8006226-2 1994 The calcium-binding proteins, calretinin, calbindin, and parvalbumin, are expressed in a variety of cortical local circuit neurons. Calcium 4-11 calbindin 2 Homo sapiens 30-40 8006226-7 1994 In addition, although the animals studied were adults, immunoreactivity for both calretinin and calbindin was found in Cajal-Retzius neurons of layer I. Dual labeling studies confirmed that with the exception of the Cajal-Retzius neurons, each calcium-binding protein was expressed in separate populations of prefrontal cortical neurons. Calcium 244-251 calbindin 2 Homo sapiens 81-91 8149593-1 1993 Calretinin, a cytosolic calcium-binding protein, is widely expressed in mammalian and chicken neurons, including subpopulations of dorsal root ganglion neurons. Calcium 24-31 calbindin 2 Homo sapiens 0-10 7941970-1 1994 The distribution of the calcium-binding protein calretinin was investigated by immunohistochemistry in the hippocampus, the subicular areas, and the entorhinal cortex in patients with Alzheimer"s disease and in control subjects. Calcium 24-31 calbindin 2 Homo sapiens 48-58 8515868-4 1993 Using a polyclonal antibody to the calcium-binding protein calretinin, we analyzed the possible changes in the subset of interneurons containing this protein in two neocortical areas that are generally devastated in Alzheimer"s disease. Calcium 35-42 calbindin 2 Homo sapiens 59-69 8515868-7 1993 These data suggest that calretinin-immunoreactive neurons, like other calcium-binding protein-containing interneurons, are resistant to degeneration in Alzheimer"s disease. Calcium 70-77 calbindin 2 Homo sapiens 24-34 1420337-1 1992 Calretinin is a cytosolic calcium-binding protein of the calmodulin superfamily, with high homology with calbindin D28k. Calcium 26-33 calbindin 2 Homo sapiens 0-10 1397083-0 1992 Expression of the calcium binding protein calretinin in WiDr cells and its correlation to their cell cycle. Calcium 18-25 calbindin 2 Homo sapiens 42-52 2001709-1 1991 Calbindin D28k and calretinin are two closely related intracellular calcium-binding proteins belonging to the troponin C superfamily. Calcium 68-75 calbindin 2 Homo sapiens 19-29 1384200-1 1992 Among the many calcium-binding proteins in the nervous system, parvalbumin, calbindin-D28K and calretinin are particularly striking in their abundance and in the specificity of their distribution. Calcium 15-22 calbindin 2 Homo sapiens 95-105 2001709-5 1991 Calretinin contains five presumably active and one presumably inactive calcium-binding domains. Calcium 71-78 calbindin 2 Homo sapiens 0-10 2001709-8 1991 Recombinant calretinin was expressed in Escherichia coli, and the calcium-binding properties were confirmed on both the natural and the recombinant proteins. Calcium 66-73 calbindin 2 Homo sapiens 12-22 34324145-3 2022 Calretinin (CR) is one of the three major types of calcium-binding proteins present in inhibitory GABAergic neurons. Calcium 51-58 calbindin 2 Homo sapiens 0-10 11900465-7 2002 Finally, we show that the calcium-binding protein Calretinin is expressed in some of these tangentially migrating cells. Calcium 26-33 calbindin 2 Homo sapiens 50-60 34768395-12 2021 Calretinin is a useful biomarker that can distinguish MM from other asbestos-related diseases and could, therefore, contribute to an earlier non-invasive diagnosis of MM. Asbestos 68-76 calbindin 2 Homo sapiens 0-10 1906795-1 1991 The genes encoding calbindin D28k (CALB1) and calretinin (CALB2), two closely related calcium-binding proteins, were mapped by in situ hybridization to the 8q21.3----q22.1 and 16q22----q23 regions of the human genome, respectively. Calcium 86-93 calbindin 2 Homo sapiens 46-56 1906795-1 1991 The genes encoding calbindin D28k (CALB1) and calretinin (CALB2), two closely related calcium-binding proteins, were mapped by in situ hybridization to the 8q21.3----q22.1 and 16q22----q23 regions of the human genome, respectively. Calcium 86-93 calbindin 2 Homo sapiens 58-63 34875924-5 2021 The maximum distance between the distal border of the TZ and the proximal border of the TZ, defined by ganglion cells in a normal density on H&E stained sections, a strong calretinin expression on mucosal nerve fibers and in >80% of submucosal and myenteric ganglion cells, with no nerve hypertrophy and absence of ganglionitis was 60 mm. Thiazoles 54-56 calbindin 2 Homo sapiens 172-182 34324145-3 2022 Calretinin (CR) is one of the three major types of calcium-binding proteins present in inhibitory GABAergic neurons. Calcium 51-58 calbindin 2 Homo sapiens 12-14 35513609-2 2022 Calretinin staining of RSB is increasingly used by experienced pathologists due to non-complex examination and comparable diagnostic accuracy with acetylcholinesterase (AChE). (1S,5S,6R)-10-(benzo[d]thiazol-6-ylsulfonyl)-5-(methoxymethyl)-3-(pyridin-2-ylethyl)-3,10-diazabicyclo[4.3.1]decan-2-one 23-26 calbindin 2 Homo sapiens 0-10 35513609-14 2022 Therefore, we recommend to use calretinin as the standard technique for staining RSB in diagnosing HD. (1S,5S,6R)-10-(benzo[d]thiazol-6-ylsulfonyl)-5-(methoxymethyl)-3-(pyridin-2-ylethyl)-3,10-diazabicyclo[4.3.1]decan-2-one 81-84 calbindin 2 Homo sapiens 31-41