PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 25264260-4 2014 Here we show that Drosophila Plk4 phosphorylates four conserved serines in the STAN motif of the core centriole protein Ana2 to enable it to bind and recruit its Sas6 partner. Serine 64-71 anastral spindle 2 Drosophila melanogaster 120-124 28202467-4 2017 We showed previously that the Drosophila Ana2 coiled-coil domain (DmCCD) is essential for centriole assembly, but it forms a tight parallel tetramer in vitro that likely precludes an interaction with PB3. dmccd 66-71 anastral spindle 2 Drosophila melanogaster 41-45 21920316-2 2011 Here, we identified a protein complex composed of the tumor suppressor anastral spindle 2 (Ana2), a dynein light-chain protein Cut up (Ctp), and Mushroom body defect (Mud), which regulates mitotic spindle orientation. Cytidine Triphosphate 135-138 anastral spindle 2 Drosophila melanogaster 91-95 24920673-10 2014 LC8 recognizes the signature TQT motif in the first LC8 binding site of Ana2, forming extensive van der Waals contacts and hydrogen bonding with the peptide, whereas the Ana2 site 2 TQC motif forms a uniquely extended beta-strand, not observed in other dynein light chain-target complexes. Hydrogen 123-131 anastral spindle 2 Drosophila melanogaster 72-76 21920316-4 2011 The centriolar protein Ana2 anchors Ctp to centrioles during ACD. Cytidine Triphosphate 36-39 anastral spindle 2 Drosophila melanogaster 23-27