PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 24973709-3 2014 Overexpression of miR-218 inhibited cell growth arrest at G2/M phase, suppressed the protein levels of cyclin A and up-regulated the expression levels of p27 through decreasing the levels of Fbxw8. mir-218 18-25 F-box and WD repeat domain containing 8 Homo sapiens 191-196 24362026-7 2014 In addition, we showed that Thr-355 of HPK1 is a key PP4 dephosphorylation site, through which CUL7/Fbxw8 ubiquitin ligase and PP4 regulates HPK1 stability. Threonine 28-31 F-box and WD repeat domain containing 8 Homo sapiens 100-105 23863152-9 2013 Under conditions of chronic insulin exposure, inactive serine-phosphorylated IRS-1 and Fbw8 co-localize to the cytosol where the former becomes ubiquitylated via CUL7/Fbw8. Serine 55-61 F-box and WD repeat domain containing 8 Homo sapiens 167-171 24083669-5 2013 Ursolic acid (UA) treatment of SNG-2 cells, an endometrial cancer cell line, decreased cyclin D1, pERK1/2, FBXW8, and Cullin1 levels in a dose- and time-dependent manner. ursolic acid 0-12 F-box and WD repeat domain containing 8 Homo sapiens 107-112 24083669-5 2013 Ursolic acid (UA) treatment of SNG-2 cells, an endometrial cancer cell line, decreased cyclin D1, pERK1/2, FBXW8, and Cullin1 levels in a dose- and time-dependent manner. ursolic acid 14-16 F-box and WD repeat domain containing 8 Homo sapiens 107-112 22524683-0 2012 Cullin 7 and Fbxw 8 expression in trophoblastic cells is regulated via oxygen tension: implications for intrauterine growth restriction? Oxygen 71-77 F-box and WD repeat domain containing 8 Homo sapiens 13-19 22524683-8 2012 In vivo, Cul7 and Fbxw8 were detected in syncytiotrophoblast cells, VT, and EVT cells. EVT 76-79 F-box and WD repeat domain containing 8 Homo sapiens 18-23