PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
15509780-8	2004	Furthermore, TRE17 cooperates with Arf6 GEFs to induce GTP loading of Arf6 in vivo.	Guanosine Triphosphate	55-58	TRE17	Homo sapiens	13-18
20418905-4	2010	TRE17 encodes a ubiquitin-specific protease (USP), and a TBC domain that mediates binding to the Arf6 GTPase.	Tubercidin	57-60	TRE17	Homo sapiens	0-5
25179595-3	2014	Here, we show that co-expression of the ubiquitin-specific protease TRE17/USP6 counteracts the MARCH-dependent targeting of CIE cargo proteins, but not that of transferrin receptor, to lysosomes, leading to recovery of the stability and cell surface level of the proteins.	chlorimuron ethyl	124-127	TRE17	Homo sapiens	68-73
25179595-5	2014	The effects of TRE17 were dependent on its deubiquitylating activity and expression of TRE17 alone led to a stabilization of surface major histocompatibility complex class I (MHCI) molecules, a CIE cargo, suggesting that deubiquitylation of endogenous CIE cargo proteins promotes their stability.	chlorimuron ethyl	194-197	TRE17	Homo sapiens	87-92
22081069-7	2012	TRE17 stimulates phosphorylation of p65 at serine 536, a modification that has been associated with enhanced transcriptional activity and nuclear retention.	Serine	43-49	TRE17	Homo sapiens	0-5
16127172-4	2005	In the current study, we identified the ubiquitous calcium (Ca2+)-binding protein calmodulin (CaM) as a novel binding partner for TRE17.	Calcium	51-58	TRE17	Homo sapiens	130-135
16127172-11	2005	Interestingly, the calcium ionophore A23187 induced accumulation of a polyubiquitinated TRE17 species.	Calcium	19-26	TRE17	Homo sapiens	88-93
16127172-11	2005	Interestingly, the calcium ionophore A23187 induced accumulation of a polyubiquitinated TRE17 species.	Calcimycin	37-43	TRE17	Homo sapiens	88-93
16127172-12	2005	The effect of A23187 was attenuated in CaM binding-deficient mutants of TRE17.	Calcimycin	14-20	TRE17	Homo sapiens	72-77
15509780-5	2004	TRE17 associates directly with Arf6 in its GDP- but not GTP-bound state.	Guanosine Diphosphate	43-46	TRE17	Homo sapiens	0-5