PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
35042574-1	2021	Insulin-induced gene 2 (INSIG2) is a recently identified gene that is implicated in the regulation of cholesterol metabolism and lipogenesis in mammals.	Cholesterol	102-113	insulin-induced gene 2 protein	Capra hircus	0-22
35042574-1	2021	Insulin-induced gene 2 (INSIG2) is a recently identified gene that is implicated in the regulation of cholesterol metabolism and lipogenesis in mammals.	Cholesterol	102-113	insulin-induced gene 2 protein	Capra hircus	24-30
35042574-6	2021	The response to overexpressing INSIG2 included down-regulation of SREBP, PPARG, FASN, ELOVL6, SCD, APGAT6 and TIP47 coupled with a decrease in content of triacylglycerol (TAG).	Triglycerides	154-169	insulin-induced gene 2 protein	Capra hircus	31-37
30594361-8	2019	The marked decrease in content of TAG and TC in response to overexpression of INSIG2, along with a modest decrease in content of TAG when INSIG1 was overexpressed, suggested that TAG synthesis is mainly regulated by INSIG2, whereas TC synthesis is equally regulated by INSIG2 and INSIG1.	Technetium	42-44	insulin-induced gene 2 protein	Capra hircus	78-84
30594361-10	2019	However, in response to simultaneous interference of INSIG1 and INSIG2, the marked increase in content of TAG and TC and accumulation of lipids along with significant upregulation of SREBF1, ACACA, SCD1, AGPAT6, and DGAT2 suggested that INSIG1 and INSIG2 synergistically regulate milk fat synthesis in GMEC.	gmec	302-306	insulin-induced gene 2 protein	Capra hircus	64-70
30594361-7	2019	Responses to overexpressing INSIG1 or INSIG2 included downregulation of SREBF1, ACACA, FASN, SCD1, GPAM, DGAT2, ATGL, and HSL coupled with a decrease in content of triacylglycerol (TAG), total cholesterol (TC), and lipid droplet accumulation.	Triglycerides	164-179	insulin-induced gene 2 protein	Capra hircus	38-44
30594361-7	2019	Responses to overexpressing INSIG1 or INSIG2 included downregulation of SREBF1, ACACA, FASN, SCD1, GPAM, DGAT2, ATGL, and HSL coupled with a decrease in content of triacylglycerol (TAG), total cholesterol (TC), and lipid droplet accumulation.	Cholesterol	193-204	insulin-induced gene 2 protein	Capra hircus	38-44
30594361-7	2019	Responses to overexpressing INSIG1 or INSIG2 included downregulation of SREBF1, ACACA, FASN, SCD1, GPAM, DGAT2, ATGL, and HSL coupled with a decrease in content of triacylglycerol (TAG), total cholesterol (TC), and lipid droplet accumulation.	Technetium	206-208	insulin-induced gene 2 protein	Capra hircus	38-44