PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
20530691-5	2010	TNIK, but not its catalytically inactive mutant, phosphorylated the conserved serine 154 residue of TCF4.	Serine	78-84	TRAF2 and NCK interacting kinase	Mus musculus	0-4
34677004-5	2022	A targeted siRNA screen was performed using immunofluorescence to detect changes in intracellular procollagen I. Tumor necrosis factor receptor associated factor 2 and noncatalytic region of tyrosine kinase-interacting kinase (TNIK) was identified and interrogated in vitro and in vivo using the TNIK kinase inhibitor NCB-0846 or RNA interference-mediated knockdown.	NCB-0846	318-326	TRAF2 and NCK interacting kinase	Mus musculus	191-225
34677004-6	2022	Our siRNA screen identified nine genes whose knockdown promoted procollagen I retention, including the serine/threonine kinase TNIK.	Serine	103-109	TRAF2 and NCK interacting kinase	Mus musculus	127-131
34677004-7	2022	Genetic deletion or pharmacologic inhibition of TNIK through the small molecule inhibitor NCB-0846 disrupted procollagen I trafficking and secretion without impacting procollagen I expression.	NCB-0846	90-98	TRAF2 and NCK interacting kinase	Mus musculus	48-52
34985886-0	2022	Discovery of 3,4-Dihydrobenzo(f)(1,4)oxazepin-5(2H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects.	3,4-dihydrobenzo(f)(1,4)oxazepin-5(2h)	13-51	TRAF2 and NCK interacting kinase	Mus musculus	96-100
34985886-2	2022	Herein, we report the discovery of a series of 3,4-dihydrobenzo(f)(1,4)oxazepin-5(2H)-one derivatives as a new class of TNIK inhibitors.	3,4-dihydrobenzo(f)(1,4)oxazepin-5(2h)-	47-86	TRAF2 and NCK interacting kinase	Mus musculus	120-124
31308798-7	2019	In the hippocampus, memantine significantly altered the expression levels of 233 proteins, among which PCNT, ATAXIN2, TNIK, and NOL3 were up-regulated, and FLNA, MARK 2 and BRAF were down-regulated.	Memantine	20-29	TRAF2 and NCK interacting kinase	Mus musculus	118-122
27562646-3	2016	Consistent with this, Tnik-deficient mice are resistant to azoxymethane-induced colon tumorigenesis, and Tnik(-/-)/Apc(min/+) mutant mice develop significantly fewer intestinal tumours.	Azoxymethane	59-71	TRAF2 and NCK interacting kinase	Mus musculus	22-26