PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
31329173-4	2019	We detail here a method for purifying a glutathione S-transferase (GST) and poly-histidine tagged Drosophila atlastin by two rounds of affinity chromatography.	polyhistidine	76-90	atlastin	Drosophila melanogaster	109-117
21690399-5	2011	Drosophila atlastin dimerizes in the presence of GTPgammaS but is monomeric with GDP or without nucleotide.	Guanosine Diphosphate	81-84	atlastin	Drosophila melanogaster	11-19
25407413-3	2015	Here, we determined the preliminary crystal structure of the cytosolic segment of Drosophila ATL in a GDP-bound state.	Guanosine Diphosphate	102-105	atlastin	Drosophila melanogaster	93-96
25407413-9	2015	These results suggest that GDP-bound ATLs may adopt multiple conformations and the in vitro fusion activity of ATL cannot be achieved by a simple collection of functional domains.	Guanosine Diphosphate	27-30	atlastin	Drosophila melanogaster	37-40
23684613-4	2013	Atlastin depletion in Drosophila fat bodies also reduced LD size and decreased triglycerides in whole animals, sensitizing them to starvation.	Triglycerides	79-92	atlastin	Drosophila melanogaster	0-8
30287684-6	2018	Here, we examined several Drosophila-human atlastin chimeras to identify functional domains of human atlastin-1 in vitro Although all chimeras could hydrolyze GTP, only chimeras containing the human C-terminal tail, hydrophobic segments, or both could fuse membranes in vitro We also determined that co-reconstitution of atlastin with reticulon does not influence GTPase activity or membrane fusion.	Guanosine Triphosphate	159-162	atlastin	Drosophila melanogaster	101-109
21690399-9	2011	GTP-dependent dimerization of atlastin generates an enzymatically active protein that drives membrane fusion after nucleotide hydrolysis and conformational reorganization.	Guanosine Triphosphate	0-3	atlastin	Drosophila melanogaster	30-38
19633650-5	2009	In vitro experiments confirm that Atlastin autonomously drives membrane fusion in a GTP-dependent fashion.	Guanosine Triphosphate	84-87	atlastin	Drosophila melanogaster	34-42
19341724-10	2009	Finally, we demonstrate that the microtubule-destabilizing drug vinblastine alleviates synapse and muscle defects in atl mutants.	Vinblastine	64-75	atlastin	Drosophila melanogaster	117-120