PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
21803134-6	2011	Cell exposure to the DL-compounds PCB126 or PCB77 in the 10(-6)-10(-9)M concentration range resulted in a 2-4-fold induction of CYPIA1 and CYP1B1, which was antagonized by alpha-naphthoflavone or PCB153.	3,4,5,3',4'-pentachlorobiphenyl	34-40	cytochrome P450 family 1 subfamily B member 1	Bos taurus	139-145
31722089-7	2020	By contrast, when BH4 or BH5 was co-cultured with previously established bovine liver sinusoidal cell lines and treated with 3-MC, the gene expression levels of CYP1A1, CYP1A2, and CYP1B1 increased by 38~290%, compared with those in BH4 or BH5 cells cultured alone.	sapropterin	18-21	cytochrome P450 family 1 subfamily B member 1	Bos taurus	181-187
31722089-7	2020	By contrast, when BH4 or BH5 was co-cultured with previously established bovine liver sinusoidal cell lines and treated with 3-MC, the gene expression levels of CYP1A1, CYP1A2, and CYP1B1 increased by 38~290%, compared with those in BH4 or BH5 cells cultured alone.	Hydrogen [(1r)-1-Hydroxy-2-(3-Pentadecyl-1h-Imidazol-3-Ium-1-Yl)-1-Phosphonoethyl]phosphonate	25-28	cytochrome P450 family 1 subfamily B member 1	Bos taurus	181-187
31722089-7	2020	By contrast, when BH4 or BH5 was co-cultured with previously established bovine liver sinusoidal cell lines and treated with 3-MC, the gene expression levels of CYP1A1, CYP1A2, and CYP1B1 increased by 38~290%, compared with those in BH4 or BH5 cells cultured alone.	Methylcholanthrene	125-129	cytochrome P450 family 1 subfamily B member 1	Bos taurus	181-187
31722089-7	2020	By contrast, when BH4 or BH5 was co-cultured with previously established bovine liver sinusoidal cell lines and treated with 3-MC, the gene expression levels of CYP1A1, CYP1A2, and CYP1B1 increased by 38~290%, compared with those in BH4 or BH5 cells cultured alone.	sapropterin	233-236	cytochrome P450 family 1 subfamily B member 1	Bos taurus	181-187
31722089-7	2020	By contrast, when BH4 or BH5 was co-cultured with previously established bovine liver sinusoidal cell lines and treated with 3-MC, the gene expression levels of CYP1A1, CYP1A2, and CYP1B1 increased by 38~290%, compared with those in BH4 or BH5 cells cultured alone.	Hydrogen [(1r)-1-Hydroxy-2-(3-Pentadecyl-1h-Imidazol-3-Ium-1-Yl)-1-Phosphonoethyl]phosphonate	240-243	cytochrome P450 family 1 subfamily B member 1	Bos taurus	181-187
31722089-5	2020	A potent carcinogen, 3-methylcholanthrene (3-MC), upregulated gene expression of cytochrome P450 (CYP)1A1, CYP1A2, and CYP1B1 in BH4 and BH5, but only to levels less than one-fifteenth of those in primary cultured bovine hepatocytes.	Methylcholanthrene	21-41	cytochrome P450 family 1 subfamily B member 1	Bos taurus	119-125
31722089-5	2020	A potent carcinogen, 3-methylcholanthrene (3-MC), upregulated gene expression of cytochrome P450 (CYP)1A1, CYP1A2, and CYP1B1 in BH4 and BH5, but only to levels less than one-fifteenth of those in primary cultured bovine hepatocytes.	Methylcholanthrene	43-47	cytochrome P450 family 1 subfamily B member 1	Bos taurus	119-125
31722089-5	2020	A potent carcinogen, 3-methylcholanthrene (3-MC), upregulated gene expression of cytochrome P450 (CYP)1A1, CYP1A2, and CYP1B1 in BH4 and BH5, but only to levels less than one-fifteenth of those in primary cultured bovine hepatocytes.	sapropterin	129-132	cytochrome P450 family 1 subfamily B member 1	Bos taurus	119-125
31722089-5	2020	A potent carcinogen, 3-methylcholanthrene (3-MC), upregulated gene expression of cytochrome P450 (CYP)1A1, CYP1A2, and CYP1B1 in BH4 and BH5, but only to levels less than one-fifteenth of those in primary cultured bovine hepatocytes.	Hydrogen [(1r)-1-Hydroxy-2-(3-Pentadecyl-1h-Imidazol-3-Ium-1-Yl)-1-Phosphonoethyl]phosphonate	137-140	cytochrome P450 family 1 subfamily B member 1	Bos taurus	119-125
21803134-6	2011	Cell exposure to the DL-compounds PCB126 or PCB77 in the 10(-6)-10(-9)M concentration range resulted in a 2-4-fold induction of CYPIA1 and CYP1B1, which was antagonized by alpha-naphthoflavone or PCB153.	3,4,3',4'-tetrachlorobiphenyl	44-49	cytochrome P450 family 1 subfamily B member 1	Bos taurus	139-145
21803134-6	2011	Cell exposure to the DL-compounds PCB126 or PCB77 in the 10(-6)-10(-9)M concentration range resulted in a 2-4-fold induction of CYPIA1 and CYP1B1, which was antagonized by alpha-naphthoflavone or PCB153.	alpha-naphthoflavone	172-192	cytochrome P450 family 1 subfamily B member 1	Bos taurus	139-145
21803134-6	2011	Cell exposure to the DL-compounds PCB126 or PCB77 in the 10(-6)-10(-9)M concentration range resulted in a 2-4-fold induction of CYPIA1 and CYP1B1, which was antagonized by alpha-naphthoflavone or PCB153.	2,4,5,2',4',5'-hexachlorobiphenyl	196-202	cytochrome P450 family 1 subfamily B member 1	Bos taurus	139-145
19167471-0	2009	Differential induction of cytochrome P450 1A1 and 1B1 mRNA in primary cultured bovine hepatocytes treated with TCDD, PBDD/Fs and feed ingredients.	Polychlorinated Dibenzodioxins	111-115	cytochrome P450 family 1 subfamily B member 1	Bos taurus	26-53
19167471-0	2009	Differential induction of cytochrome P450 1A1 and 1B1 mRNA in primary cultured bovine hepatocytes treated with TCDD, PBDD/Fs and feed ingredients.	pbdd/fs	117-124	cytochrome P450 family 1 subfamily B member 1	Bos taurus	26-53
19167471-1	2009	This study investigates the dose-dependent expression of CYP1A1 and CYP1B1 in primary cultured bovine hepatocytes exposed to TCDD, several polybrominated dibenzo-p-dioxins and furans (PBDD/Fs) congeners and fish oil used as animal feed ingredients to identify their dioxin-like potentials.	Polychlorinated Dibenzodioxins	125-129	cytochrome P450 family 1 subfamily B member 1	Bos taurus	68-74
19167471-1	2009	This study investigates the dose-dependent expression of CYP1A1 and CYP1B1 in primary cultured bovine hepatocytes exposed to TCDD, several polybrominated dibenzo-p-dioxins and furans (PBDD/Fs) congeners and fish oil used as animal feed ingredients to identify their dioxin-like potentials.	dibenzo(1,4)dioxin	154-171	cytochrome P450 family 1 subfamily B member 1	Bos taurus	68-74
19167471-1	2009	This study investigates the dose-dependent expression of CYP1A1 and CYP1B1 in primary cultured bovine hepatocytes exposed to TCDD, several polybrominated dibenzo-p-dioxins and furans (PBDD/Fs) congeners and fish oil used as animal feed ingredients to identify their dioxin-like potentials.	Furans	176-182	cytochrome P450 family 1 subfamily B member 1	Bos taurus	68-74
19167471-1	2009	This study investigates the dose-dependent expression of CYP1A1 and CYP1B1 in primary cultured bovine hepatocytes exposed to TCDD, several polybrominated dibenzo-p-dioxins and furans (PBDD/Fs) congeners and fish oil used as animal feed ingredients to identify their dioxin-like potentials.	pbdd/fs	184-191	cytochrome P450 family 1 subfamily B member 1	Bos taurus	68-74
19167471-1	2009	This study investigates the dose-dependent expression of CYP1A1 and CYP1B1 in primary cultured bovine hepatocytes exposed to TCDD, several polybrominated dibenzo-p-dioxins and furans (PBDD/Fs) congeners and fish oil used as animal feed ingredients to identify their dioxin-like potentials.	Dioxins	164-170	cytochrome P450 family 1 subfamily B member 1	Bos taurus	68-74
19167471-3	2009	Quantitative real time polymerase chain reaction analysis (qRT-PCR) showed that relative mRNA levels for CYP1A1 and CYP1B1 exhibited a dose-dependent induction by TCDD.	Polychlorinated Dibenzodioxins	163-167	cytochrome P450 family 1 subfamily B member 1	Bos taurus	116-122
19167471-4	2009	The EC(50) of the TCDD concentration for CYP1A1 expression was approximately 4-fold less than that of CYP1B1.	Polychlorinated Dibenzodioxins	18-22	cytochrome P450 family 1 subfamily B member 1	Bos taurus	102-108