PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
22105792-2	2012	In this study, we found that vitamin C (Vc) was capable of inducing telomerase activity in periodontal ligament stem cells (PDLSCs), leading to the up-regulated expression of extracellular matrix type I collagen, fibronectin, and integrin beta1, stem cell markers Oct4, Sox2, and Nanog as well as osteogenic markers RUNX2, ALP, OCN.	Ascorbic Acid	29-38	homeobox protein NANOG	Sus scrofa	280-285
22785354-11	2012	Finally, blastocysts derived following treatment with 3-MA or rapamycin exhibited significantly decreased expression of selected transcription factors, including Pou5f1, Sox2 and Nanog.	3-methyladenine	54-58	homeobox protein NANOG	Sus scrofa	179-184
22785354-11	2012	Finally, blastocysts derived following treatment with 3-MA or rapamycin exhibited significantly decreased expression of selected transcription factors, including Pou5f1, Sox2 and Nanog.	Sirolimus	62-71	homeobox protein NANOG	Sus scrofa	179-184
19502222-4	2009	We showed that porcine iPS cells expressed alkaline phosphatase, SSEA3, SSEA4, Tra-1-60, Tra-1-81, Oct3/4, Nanog, Sox2, Rex1 and CDH1.	IPS	23-26	homeobox protein NANOG	Sus scrofa	107-112
29412739-7	2018	In addition, MC1568 treatment stimulated expression of the development-related genes OCT4, CDX2, SOX2, and NANOG in SCNT blastocysts.	MC1568	13-19	homeobox protein NANOG	Sus scrofa	107-112
26604326-5	2016	BIX-01294 treatment significantly decreased the levels of H3K9me2 and H3K9me at the 2- and 4-cell stages, which are associated with embryo genetic activation, and increased the transcriptional expression of the pluripotency genes SOX2, NANOG and OCT4 in cloned blastocysts.	BIX 01294	0-9	homeobox protein NANOG	Sus scrofa	236-241
26053519-5	2015	When 5-aza-2"-deoxycytidine (5-aza-dC) or trichostatin A (TSA) enhanced the development of porcine cloned embryos, Nanog methylation reprogramming was also improved, similar to that detected in fertilized counterparts.	Decitabine	5-27	homeobox protein NANOG	Sus scrofa	115-120
26053519-5	2015	When 5-aza-2"-deoxycytidine (5-aza-dC) or trichostatin A (TSA) enhanced the development of porcine cloned embryos, Nanog methylation reprogramming was also improved, similar to that detected in fertilized counterparts.	Decitabine	29-37	homeobox protein NANOG	Sus scrofa	115-120
26053519-5	2015	When 5-aza-2"-deoxycytidine (5-aza-dC) or trichostatin A (TSA) enhanced the development of porcine cloned embryos, Nanog methylation reprogramming was also improved, similar to that detected in fertilized counterparts.	trichostatin A	42-56	homeobox protein NANOG	Sus scrofa	115-120
26053519-5	2015	When 5-aza-2"-deoxycytidine (5-aza-dC) or trichostatin A (TSA) enhanced the development of porcine cloned embryos, Nanog methylation reprogramming was also improved, similar to that detected in fertilized counterparts.	trichostatin A	58-61	homeobox protein NANOG	Sus scrofa	115-120
26053519-7	2015	In conclusion, our results demonstrated that the epigenetic modification agent 5-aza-dC or TSA improved Nanog methylation reprogramming and the expression patterns of pluripotent transcription factors, thereby resulting in the enhanced expression of Nanog and high development of porcine cloned embryos.	Decitabine	79-87	homeobox protein NANOG	Sus scrofa	104-109
26053519-7	2015	In conclusion, our results demonstrated that the epigenetic modification agent 5-aza-dC or TSA improved Nanog methylation reprogramming and the expression patterns of pluripotent transcription factors, thereby resulting in the enhanced expression of Nanog and high development of porcine cloned embryos.	Decitabine	79-87	homeobox protein NANOG	Sus scrofa	250-255
26053519-7	2015	In conclusion, our results demonstrated that the epigenetic modification agent 5-aza-dC or TSA improved Nanog methylation reprogramming and the expression patterns of pluripotent transcription factors, thereby resulting in the enhanced expression of Nanog and high development of porcine cloned embryos.	trichostatin A	91-94	homeobox protein NANOG	Sus scrofa	104-109
26053519-7	2015	In conclusion, our results demonstrated that the epigenetic modification agent 5-aza-dC or TSA improved Nanog methylation reprogramming and the expression patterns of pluripotent transcription factors, thereby resulting in the enhanced expression of Nanog and high development of porcine cloned embryos.	trichostatin A	91-94	homeobox protein NANOG	Sus scrofa	250-255
32070424-8	2020	Activin A directly regulates the expression of pig NANOG via SMAD2/3; inhibition of this pathway by SB431542 resulted in inhibition of NANOG expression.	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	100-108	homeobox protein NANOG	Sus scrofa	135-140
31298467-1	2019	The present study sought to examine whether trichostatin A (TSA)-assisted epigenetic transformation of porcine bone marrow (BM)-derived mesenchymal stem cells (BM-MSCs) affects the transcriptional activities of pluripotency-related genes (Oct4, Nanog, c-Myc, Sox2 and Rex1), multipotent stemness-related gene (Nestin) and anti-apoptotic/anti-senescence-related gene (Survivin).	trichostatin A	44-58	homeobox protein NANOG	Sus scrofa	245-250
31298467-1	2019	The present study sought to examine whether trichostatin A (TSA)-assisted epigenetic transformation of porcine bone marrow (BM)-derived mesenchymal stem cells (BM-MSCs) affects the transcriptional activities of pluripotency-related genes (Oct4, Nanog, c-Myc, Sox2 and Rex1), multipotent stemness-related gene (Nestin) and anti-apoptotic/anti-senescence-related gene (Survivin).	trichostatin A	60-63	homeobox protein NANOG	Sus scrofa	245-250
31298467-4	2019	This has been confirmed by the relative abundances for Nanog, c-Myc Rex1, Sox2 and Survivin mRNAs in TSA-exposed BM-MSCs that turned out to be significantly higher than those of TSA-unexposed BM-MSCs.	trichostatin A	101-104	homeobox protein NANOG	Sus scrofa	55-60
31298467-6	2019	In conclusion, the considerably elevated quantitative profiles of Sox2, Rex1, c-Myc, Nanog and Survivin mRNA transcripts seem to trigger improved reprogrammability of TSA-treated BM-MSC nuclei in cloned pig embryos that thereby displayed remarkably increased blastocyst formation rates as compared to those noticed for embryos derived from TSA-untreated BM-MSCs.	trichostatin A	167-170	homeobox protein NANOG	Sus scrofa	85-90