PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 33776618-4 2021 Objective: We investigated the effects of water extract from AAL on high-fat-diet (HFD)-induced obese mice and 3T3-L1 adipocytes to develop a new functional food material. Water 42-47 active avoidance learning Mus musculus 61-64 12757412-1 2003 An antitumour lectin (named AAL) consisting of two identical subunits of 15.8 kDa was isolated from the fruiting bodies of the edible mushroom Agrocybe aegerita using a procedure which involved precipitating the extract by addition of (NH(4))(2)SO(4), ion exchange chromatography on DEAE-Sepharose Fast Flow, gel filtration chromatography on Sephacryl S-200 HR and finally purification on a GF-250 HPLC column. deae-sepharose 283-297 active avoidance learning Mus musculus 28-31 12757412-1 2003 An antitumour lectin (named AAL) consisting of two identical subunits of 15.8 kDa was isolated from the fruiting bodies of the edible mushroom Agrocybe aegerita using a procedure which involved precipitating the extract by addition of (NH(4))(2)SO(4), ion exchange chromatography on DEAE-Sepharose Fast Flow, gel filtration chromatography on Sephacryl S-200 HR and finally purification on a GF-250 HPLC column. sephacryl s 342-353 active avoidance learning Mus musculus 28-31 12757412-5 2003 Analysis by Hoechst 33258 staining, MitoSensor Kit and flow cytometry showed that AAL induced apoptosis in HeLa cells. hoechst 12-19 active avoidance learning Mus musculus 82-85 12689522-9 2003 The result of IEF suggested that AAL attached to TMV particles. tmv 49-52 active avoidance learning Mus musculus 33-36 33776618-12 2021 AAL also reduced serum cholesterol, triglyceride, and LDL-C and increased HDL-C levels. Cholesterol 23-34 active avoidance learning Mus musculus 0-3 33776618-12 2021 AAL also reduced serum cholesterol, triglyceride, and LDL-C and increased HDL-C levels. Triglycerides 36-48 active avoidance learning Mus musculus 0-3 33776618-14 2021 In vitro, Oil Red O staining showed that AAL inhibited adipose differentiation by down-regulating the gene and protein expression of PPARgamma and C/EBPalpha. oil red O 10-19 active avoidance learning Mus musculus 41-44 33776618-16 2021 Conclusion: AAL water-soluble extract has a significant anti-adipogenic effect in the HFD-induced obese mice model. Water 16-21 active avoidance learning Mus musculus 12-15 32014631-2 2020 We found the methanol extract of Acalypha australis L. (AAL) to be the most effective. Methanol 13-21 active avoidance learning Mus musculus 56-59 26638121-3 2016 The hemagglutinating activity of AAL was maintained after incubation at a wide range of temperature (40 to 70 C) and pH, was shown to be dependent on divalent cations, and was inhibited by d-mannose and d-sucrose. Mannose 190-199 active avoidance learning Mus musculus 33-36 26638121-3 2016 The hemagglutinating activity of AAL was maintained after incubation at a wide range of temperature (40 to 70 C) and pH, was shown to be dependent on divalent cations, and was inhibited by d-mannose and d-sucrose. Sucrose 204-213 active avoidance learning Mus musculus 33-36 26638121-4 2016 AAL showed an electrophoretic profile in sodium dodecyl sulfate-polyacrylamide gel electrophoresis similar to other lectins of the tribe Dalbergieae, presenting a double band of molecular weight with approximately 20 kDa and other minor bands of 17, 15, and 13 kDa, being the smaller fragment glycosylated. Sodium Dodecyl Sulfate 41-63 active avoidance learning Mus musculus 0-3 26638121-4 2016 AAL showed an electrophoretic profile in sodium dodecyl sulfate-polyacrylamide gel electrophoresis similar to other lectins of the tribe Dalbergieae, presenting a double band of molecular weight with approximately 20 kDa and other minor bands of 17, 15, and 13 kDa, being the smaller fragment glycosylated. polyacrylamide 64-78 active avoidance learning Mus musculus 0-3 26638121-5 2016 AAL injected by intravenous route in mice showed antinociceptive activity in two behavioral tests (writhing and formalin). Formaldehyde 112-120 active avoidance learning Mus musculus 0-3 26638121-6 2016 In the writhing test induced by acetic acid, AAL showed inhibitory effect at 0.01 mg/kg (68%), 0.1 mg/kg (46%) and 1 mg/kg (74%). Acetic Acid 32-43 active avoidance learning Mus musculus 45-48 26638121-7 2016 In the formalin test, AAL (0.1 mg/kg) inhibited by 48% the licking time in the inflammatory phase, an effect that was recovered by the lectin association with mannose. Formaldehyde 7-15 active avoidance learning Mus musculus 22-25 26638121-7 2016 In the formalin test, AAL (0.1 mg/kg) inhibited by 48% the licking time in the inflammatory phase, an effect that was recovered by the lectin association with mannose. Mannose 159-166 active avoidance learning Mus musculus 22-25