PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
29255404-1	2017	Calcium and integrin-binding protein 2 (CIB2) belongs to a protein family with four known members, CIB1 through CIB4, which are characterized by multiple calcium-binding EF-hand domains.	Calcium	154-161	calcium and integrin binding 1 (calmyrin)	Mus musculus	99-103
28939911-0	2017	CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	22-26	calcium and integrin binding 1 (calmyrin)	Mus musculus	0-4
28939911-1	2017	Calcium and integrin binding protein 1 (CIB1) is a calcium-binding protein that was initially identified as a binding partner of platelet integrin alphaIIb.	Calcium	51-58	calcium and integrin binding 1 (calmyrin)	Mus musculus	0-38
28939911-1	2017	Calcium and integrin binding protein 1 (CIB1) is a calcium-binding protein that was initially identified as a binding partner of platelet integrin alphaIIb.	Calcium	51-58	calcium and integrin binding 1 (calmyrin)	Mus musculus	40-44
28939911-3	2017	Here, we show that CIB1 negatively regulates degeneration of dopaminergic neurons in a mouse model of Parkinson"s disease using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	128-172	calcium and integrin binding 1 (calmyrin)	Mus musculus	19-23
28939911-3	2017	Here, we show that CIB1 negatively regulates degeneration of dopaminergic neurons in a mouse model of Parkinson"s disease using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	174-178	calcium and integrin binding 1 (calmyrin)	Mus musculus	19-23
28939911-4	2017	Genetic deficiency of the CIB1 gene enhances MPTP-induced neurotoxicity in dopaminergic neurons in CIB1-/- mice.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	45-49	calcium and integrin binding 1 (calmyrin)	Mus musculus	26-30
28939911-4	2017	Genetic deficiency of the CIB1 gene enhances MPTP-induced neurotoxicity in dopaminergic neurons in CIB1-/- mice.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	45-49	calcium and integrin binding 1 (calmyrin)	Mus musculus	99-103
28939911-5	2017	Furthermore, RNAi-mediated depletion of CIB1 in primary dopaminergic neurons potentiated 1-methyl-4-phenyl pyrinidium (MPP+)-induced neuronal death.	1-methyl-4-phenyl pyrinidium	89-117	calcium and integrin binding 1 (calmyrin)	Mus musculus	40-44
28939911-5	2017	Furthermore, RNAi-mediated depletion of CIB1 in primary dopaminergic neurons potentiated 1-methyl-4-phenyl pyrinidium (MPP+)-induced neuronal death.	mangion-purified polysaccharide (Candida albicans)	119-123	calcium and integrin binding 1 (calmyrin)	Mus musculus	40-44
28939911-6	2017	CIB1 physically associated with apoptosis signal-regulating kinase 1 (ASK1) and thereby inhibited the MPP+-induced stimulation of the ASK1-mediated signaling cascade.	mangion-purified polysaccharide (Candida albicans)	102-106	calcium and integrin binding 1 (calmyrin)	Mus musculus	0-4
28939911-7	2017	These findings suggest that CIB1 plays a protective role in MPTP/MPP+-induced neurotoxicity by blocking ASK1-mediated signaling.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	60-64	calcium and integrin binding 1 (calmyrin)	Mus musculus	28-32
28939911-7	2017	These findings suggest that CIB1 plays a protective role in MPTP/MPP+-induced neurotoxicity by blocking ASK1-mediated signaling.	mangion-purified polysaccharide (Candida albicans)	65-69	calcium and integrin binding 1 (calmyrin)	Mus musculus	28-32
26840179-1	2016	Organic-inorganic nanocomposite, namely chitosan immobilized Bentonite (CIB) with chitosan content of 5% was synthesized in an acetic acid solution (2%).	Chitosan	40-48	calcium and integrin binding 1 (calmyrin)	Mus musculus	72-75
26840179-1	2016	Organic-inorganic nanocomposite, namely chitosan immobilized Bentonite (CIB) with chitosan content of 5% was synthesized in an acetic acid solution (2%).	Bentonite	61-70	calcium and integrin binding 1 (calmyrin)	Mus musculus	72-75
26840179-1	2016	Organic-inorganic nanocomposite, namely chitosan immobilized Bentonite (CIB) with chitosan content of 5% was synthesized in an acetic acid solution (2%).	Chitosan	82-90	calcium and integrin binding 1 (calmyrin)	Mus musculus	72-75
26840179-1	2016	Organic-inorganic nanocomposite, namely chitosan immobilized Bentonite (CIB) with chitosan content of 5% was synthesized in an acetic acid solution (2%).	Acetic Acid	127-138	calcium and integrin binding 1 (calmyrin)	Mus musculus	72-75
26047020-10	2015	The capsaicin group also demonstrated a significant reduction (P < 0.05) in the metastatic burden compared to the controls, which correlated to a reduction in p27(Kip) (1) expression and neuroendocrine differentiation in prostate tumors.	Capsaicin	4-13	calcium and integrin binding 1 (calmyrin)	Mus musculus	166-169
23296617-0	2013	Screening for novel calcium-binding proteins that regulate cardiac hypertrophy: CIB1 as an example.	Calcium	20-27	calcium and integrin binding 1 (calmyrin)	Mus musculus	80-84
23296617-3	2013	In this regard, we have recently identified the calcium-binding protein CIB1 as an important regulator of pathological cardiac hypertrophy and transition to heart failure.	Calcium	48-55	calcium and integrin binding 1 (calmyrin)	Mus musculus	72-76
20823108-6	2010	Western blot analysis revealed that honokiol: (i) inhibited the levels of cyclins D1, D2 and E and associated cyclin-dependent kinases (CDKs)2, CDK4 and CDK6, (ii) upregulated Cip/p21 and Kip/p27 and (iii) inhibited the levels of phosphatidylinositol 3-kinase and the phosphorylation of Akt at Ser(473) in UVB-induced skin tumors.	honokiol	36-44	calcium and integrin binding 1 (calmyrin)	Mus musculus	188-191
19691476-12	2009	Spreading could be restored in Cib1 null platelets by the addition of exogenous ADP.	Adenosine Diphosphate	80-83	calcium and integrin binding 1 (calmyrin)	Mus musculus	31-35
19375524-4	2009	Saikosaponin a also caused G0/G1 arrest of activated T cells through down-regulating the protein levels of CDK6 and Cyclin D3 and up-regulating the protein level of p27(kip).	saikosaponin D	0-14	calcium and integrin binding 1 (calmyrin)	Mus musculus	169-172
19126389-4	2009	The mice were immunized with the polyacrylamide gel particles containing the CIB fusion protein for polyclonal antibody preparation.	polyacrylamide	33-47	calcium and integrin binding 1 (calmyrin)	Mus musculus	77-80
16982698-1	2006	CIB1 is a 22-kDa calcium binding, regulatory protein with approximately 50% homology to calmodulin and calcineurin B.	Calcium	17-24	calcium and integrin binding 1 (calmyrin)	Mus musculus	0-4
12651910-7	2003	The capacity of Snk to induce morphological changes was inhibited by the calcium- and integrin-binding protein CIB.	Calcium	73-80	calcium and integrin binding 1 (calmyrin)	Mus musculus	111-114
12234997-10	2002	Treatment of cells with RU 486, a glucocorticoid receptor blocker, reversed the effects of corticosterone on cell growth and KIP/P27 protein levels suggesting the involvement of the glucocorticoid receptor in accounting for these effects.	Mifepristone	24-30	calcium and integrin binding 1 (calmyrin)	Mus musculus	125-128
12032153-7	2002	Ser(22) is also indispensable for the antiproliferative effect of RA and necessary for the RA-induced down-regulation of p21(CIP) and p27(KIP) CKIs proteins that are known to be involved in the control of cell cycle progression.	Serine	0-3	calcium and integrin binding 1 (calmyrin)	Mus musculus	138-141
11032837-0	2001	Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).	purine	163-169	calcium and integrin binding 1 (calmyrin)	Mus musculus	205-208
11032837-0	2001	Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).	Pyrimidine Nucleosides	174-196	calcium and integrin binding 1 (calmyrin)	Mus musculus	205-208
34808241-7	2022	These results suggest a model where IRE1alpha activation state drives CIB1 binding either to the InsP3R or ASK1 to regulate ER calcium efflux, ROS and DNA repair responses following UV.	Calcium	127-134	calcium and integrin binding 1 (calmyrin)	Mus musculus	70-74
31530712-0	2019	----Calcium-induced dissociation of CIB1 from ASK1 regulates agonist-induced activation of the p38 MAPK pathway in platelets.	Calcium	4-11	calcium and integrin binding 1 (calmyrin)	Mus musculus	36-40