PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 32277787-9 2020 Esrrb and Tfcp2l1 are key downstream targets of LincQ and Sox2, since overexpression of Esrrb and Tfcp2l1 can restore the loss of embryonic stem cell pluripotency that is induced by LincQ depletion. lincq 48-53 estrogen related receptor, beta Mus musculus 0-5 11297507-0 2001 Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR beta. Diethylstilbestrol 0-18 estrogen related receptor, beta Mus musculus 106-114 11297507-2 2001 Here, we show that the synthetic estrogen diethylstilbestrol (DES) promotes coactivator release from ERR beta and inhibits its transcriptional activity. Diethylstilbestrol 42-60 estrogen related receptor, beta Mus musculus 101-109 11297507-2 2001 Here, we show that the synthetic estrogen diethylstilbestrol (DES) promotes coactivator release from ERR beta and inhibits its transcriptional activity. Diethylstilbestrol 62-65 estrogen related receptor, beta Mus musculus 101-109 34077681-4 2021 Our results showed that fruquintinib-treated cells expressed higher levels of pluripotent markers, including Oct4, Nanog, Sox2, and Esrrb under serum and leukemia inhibitory factor (LIF) condition, whereas the expression of phosphorylated Erk1/2 was restricted. HMPL-013 24-36 estrogen related receptor, beta Mus musculus 132-137 32277787-9 2020 Esrrb and Tfcp2l1 are key downstream targets of LincQ and Sox2, since overexpression of Esrrb and Tfcp2l1 can restore the loss of embryonic stem cell pluripotency that is induced by LincQ depletion. lincq 48-53 estrogen related receptor, beta Mus musculus 88-93 31492838-0 2019 Next-generation unnatural monosaccharides reveal that ESRRB O-GlcNAcylation regulates pluripotency of mouse embryonic stem cells. Monosaccharides 26-41 estrogen related receptor, beta Mus musculus 54-59 31492838-7 2019 Mechanistically, ESRRB is O-GlcNAcylated by O-GlcNAc transferase at serine 25, which stabilizes ESRRB, promotes its transcription activity and facilitates its interactions with two master pluripotency regulators, OCT4 and NANOG. Serine 68-74 estrogen related receptor, beta Mus musculus 17-22 31492838-7 2019 Mechanistically, ESRRB is O-GlcNAcylated by O-GlcNAc transferase at serine 25, which stabilizes ESRRB, promotes its transcription activity and facilitates its interactions with two master pluripotency regulators, OCT4 and NANOG. Serine 68-74 estrogen related receptor, beta Mus musculus 96-101 28130335-4 2017 Isolated adult cardiomyocytes from the MHC-ERRB KO mice showed an increase in calcium sensitivity and impaired cardiomyocyte contractility, which preceded echocardiographic cardiac remodeling and dysfunction by several months. Calcium 78-85 estrogen related receptor, beta Mus musculus 43-47 31126612-5 2019 We revealed no changes in ERRs expression but alterations in ERRbeta and gamma localization in G-15-treated cells when compared to control. G-15 95-99 estrogen related receptor, beta Mus musculus 61-68 24053666-6 2013 Sox2-Cre:Errbeta+/lox heterozygotes were obese, had increased Npy and Agrp gene expression in the arcuate nucleus of the hypothalamus, and secreted more corticosterone in response to stress. Corticosterone 153-167 estrogen related receptor, beta Mus musculus 9-16 24481529-10 2014 Cardiac-specific overexpression of Errbeta led to glycogen storage, cardiac dilation, and sudden cardiac death around 3-4 weeks of age. Glycogen 50-58 estrogen related receptor, beta Mus musculus 35-42 28169326-4 2017 Alanine scanning mutation of Epep revealed residues critical for Tbx3, Klf4 and Esrrb transcript repression, cell-cell contact abrogation, cell survival in suspension, STAT3 phosphorylation and water solubility. Alanine 0-7 estrogen related receptor, beta Mus musculus 80-85 25491368-10 2015 Vitamin C also promoted DNA demethylation, including of pluripotency gene promoters (Tbx3, Tcl1, and Esrrb) and ESC-specific miRNA promoters (miR-290-295 and miR-17-92 clusters), and DNA hydroxymethylation, including of the intergenic differentially methylated region of the Dlk1-Dio3 region. Ascorbic Acid 0-9 estrogen related receptor, beta Mus musculus 101-106 23395962-9 2013 Co-expression of NANOG and TET1 increases 5-hydroxymethylcytosine levels at the top-ranked common target loci Esrrb and Oct4 (also called Pou5f1), resulting in priming of their expression before reprogramming to naive pluripotency. 5-hydroxymethylcytosine 42-65 estrogen related receptor, beta Mus musculus 110-115 22457827-7 2012 Conversely, stimulation of ERRbeta with a selective agonist (GSK4716) in a TAL cell line stimulated NKCC2 expression. GSK 4716 61-68 estrogen related receptor, beta Mus musculus 27-34 20534447-5 2010 ERRbeta coordinates expression of multiple genes that are rate-limiting regulators of ATP generation and consumption in photoreceptors. Adenosine Triphosphate 86-89 estrogen related receptor, beta Mus musculus 0-7 19136965-3 2009 Here we show that the orphan nuclear receptor Esrrb functions in conjunction with Oct4 and Sox2 to mediate reprogramming of mouse embryonic fibroblasts (MEFs) to iPS cells. IPS 162-165 estrogen related receptor, beta Mus musculus 46-51