PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 33061425-12 2020 Paclitaxel treatment inhibited the expression of circ-BIRC6 and YWHAZ while promoted the expression of miR-877-5p. Paclitaxel 0-10 baculoviral IAP repeat-containing 6 Mus musculus 54-59 33061425-13 2020 Circ-BIRC6 overexpression or miR-877-5p interference reversed the inhibitory effect of paclitaxel on HCC tumorigenesis. Paclitaxel 87-97 baculoviral IAP repeat-containing 6 Mus musculus 5-10 33061425-14 2020 Moreover, miR-877-5p could specially bind to YWHAZ, and its knockdown abated the suppressive effect of circ-BIRC6 depletion on HCC tumorigenesis. mir-877-5p 10-20 baculoviral IAP repeat-containing 6 Mus musculus 108-113 33061425-17 2020 Conclusion: Paclitaxel limited HCC tumorigenesis via modulating circ-BIRC6/miR-877-5p/YWHAZ axis, providing a novel therapeutic approach for the treatment of HCC. Paclitaxel 12-22 baculoviral IAP repeat-containing 6 Mus musculus 69-74 25196217-11 2015 The in vivo study showed that BIRC6 knockdown inhibited xenograft tumor growth and increased the sensitivity of tumor cells to sorafenib in nude mice. Sorafenib 127-136 baculoviral IAP repeat-containing 6 Mus musculus 30-35 21091633-8 2011 Targeted knockdown of Apollon sensitized CML cells to nilotinib-induced apoptosis, indicating that this is an important factor underlying MLN8237"s ability to increase the efficacy of nilotinib. nilotinib 54-63 baculoviral IAP repeat-containing 6 Mus musculus 22-29 21091633-8 2011 Targeted knockdown of Apollon sensitized CML cells to nilotinib-induced apoptosis, indicating that this is an important factor underlying MLN8237"s ability to increase the efficacy of nilotinib. nilotinib 184-193 baculoviral IAP repeat-containing 6 Mus musculus 22-29 33815677-2 2021 BRUCE facilitates DNA damage repair to protect the mouse liver against the hepatocarcinogen diethylnitrosamine (DEN)-dependent acute liver injury and carcinogenesis. Diethylnitrosamine 92-110 baculoviral IAP repeat-containing 6 Mus musculus 0-5 33815677-2 2021 BRUCE facilitates DNA damage repair to protect the mouse liver against the hepatocarcinogen diethylnitrosamine (DEN)-dependent acute liver injury and carcinogenesis. Diethylnitrosamine 112-115 baculoviral IAP repeat-containing 6 Mus musculus 0-5