PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
34286514-0	2021	LncRNA PCGEM1 mediates oxaliplatin resistance in hepatocellular carcinoma via miR-129-5p/ETV1 axis in vitro.	Oxaliplatin	23-34	PCGEM1 prostate-specific transcript	Homo sapiens	7-13
34286514-3	2021	OBJECTIVES: Our research aimed to explore the function and molecular mechanism of lncRNA PCGEM1 on oxaliplatin resistance of HCC in vitro.	Oxaliplatin	99-110	PCGEM1 prostate-specific transcript	Homo sapiens	89-95
34286514-4	2021	MATERIAL AND METHODS: Expression of the lncRNA PCGEM1, together with miR-129-5p, and the mRNA level of ETV1 and drug resistance-related genes including LRPA, MDR1 and MDR3 were determined using quantitative real-time polymerase chain reaction (RT-qPCR) in an oxaliplatin-resistant HCC cell line (Hep3B/OXA).	Oxaliplatin	259-270	PCGEM1 prostate-specific transcript	Homo sapiens	47-53
34286514-10	2021	CONCLUSIONS: Our findings demonstrated that PCGEM1 modulated oxaliplatin resistance by targeting the miR-129-5p/ETV1 pathway in HCC in vitro, suggesting a potential strategy for the treatment of chemoresistant HCC.	Oxaliplatin	61-72	PCGEM1 prostate-specific transcript	Homo sapiens	44-50
32787827-10	2020	MiR-433-3p was proven be sponged by PCGEM1.	mir-433-3p	0-10	PCGEM1 prostate-specific transcript	Homo sapiens	36-42
34261474-10	2021	MiR-590-3p was confirmed to be a downstream gene of PCGEM1.	mir-590-3p	0-10	PCGEM1 prostate-specific transcript	Homo sapiens	52-58
35109849-14	2022	miR-506-3p may interact with PCGEM1 or TRIAP1, and the suppressive effect of PCGEM1 knockdown was reversed when TRIAP1 or a miR-506-3p inhibitor was cotransfected.	mir-506-3p	0-10	PCGEM1 prostate-specific transcript	Homo sapiens	29-35
35109849-14	2022	miR-506-3p may interact with PCGEM1 or TRIAP1, and the suppressive effect of PCGEM1 knockdown was reversed when TRIAP1 or a miR-506-3p inhibitor was cotransfected.	mir-506-3p	0-10	PCGEM1 prostate-specific transcript	Homo sapiens	77-83
35109849-14	2022	miR-506-3p may interact with PCGEM1 or TRIAP1, and the suppressive effect of PCGEM1 knockdown was reversed when TRIAP1 or a miR-506-3p inhibitor was cotransfected.	-506-3p	127-134	PCGEM1 prostate-specific transcript	Homo sapiens	77-83
34160339-0	2021	Fibroblast-like Synoviocytes-derived Exosomal PCGEM1 Accelerates IL-1beta-induced Apoptosis and Cartilage Matrix Degradation by miR-142-5p/RUNX2 in Chondrocytes.	mir-142-5p	128-138	PCGEM1 prostate-specific transcript	Homo sapiens	46-52
34160339-11	2021	MiR-142-5p inhibitor offset exosomal PCGEM1 knockdown-mediated effects on the apoptosis and cartilage matrix degradation of IL-1beta-induced chondrocytes.	mir-142-5p	0-10	PCGEM1 prostate-specific transcript	Homo sapiens	37-43
34160339-12	2021	RUNX2 overexpression counteracted the suppressive effect of miR-142-5p mimic on apoptosis and cartilage matrix degradation of IL-1beta-induced chondrocytes.Conclusion: Exosomal PCGEM1 from OA-FLSs facilitated IL-1beta-induced apoptosis and cartilage matrix degradation in chondrocytes by sequestering miR-142-5p and upregulating RUNX2, which offered new insights into the pathogenesis of OA.	mir-142-5p	60-70	PCGEM1 prostate-specific transcript	Homo sapiens	177-183
34160339-12	2021	RUNX2 overexpression counteracted the suppressive effect of miR-142-5p mimic on apoptosis and cartilage matrix degradation of IL-1beta-induced chondrocytes.Conclusion: Exosomal PCGEM1 from OA-FLSs facilitated IL-1beta-induced apoptosis and cartilage matrix degradation in chondrocytes by sequestering miR-142-5p and upregulating RUNX2, which offered new insights into the pathogenesis of OA.	mir-142-5p	301-311	PCGEM1 prostate-specific transcript	Homo sapiens	177-183
32787827-13	2020	CONCLUSIONS: PCGEM1 accelerates NSCLC progression via sponging miR-433-3p to upregulate WTAP.	mir-433	63-70	PCGEM1 prostate-specific transcript	Homo sapiens	13-19
32445497-4	2020	And LV3-shRNA-PCGEM1 was able to increase the baicalein-induced inhibitory effects on LNCaP cells, and the susceptibility was 2.3 fold higher than that of baicalein alone.	baicalein	46-55	PCGEM1 prostate-specific transcript	Homo sapiens	14-20
32445497-4	2020	And LV3-shRNA-PCGEM1 was able to increase the baicalein-induced inhibitory effects on LNCaP cells, and the susceptibility was 2.3 fold higher than that of baicalein alone.	baicalein	155-164	PCGEM1 prostate-specific transcript	Homo sapiens	14-20
32520202-11	2020	PCGEM1 overexpression enhanced the anti-inflammatory effects and promoted effects on pulmonary function of montelukast sodium in CVA children and OVA-sensitized asthmatic mice.	montelukast	107-125	PCGEM1 prostate-specific transcript	Homo sapiens	0-6
32520202-13	2020	This study demonstrated the anti-inflammatory and lung-protective effects of montelukast sodium on CVA, which was strengthened by overexpression of PCGEM1.	montelukast	77-95	PCGEM1 prostate-specific transcript	Homo sapiens	148-154
25512540-5	2014	PCGEM1 promotes glucose uptake for aerobic glycolysis, coupling with the pentose phosphate shunt to facilitate biosynthesis of nucleotide and lipid, and generates NADPH for redox homeostasis.	Glucose	16-23	PCGEM1 prostate-specific transcript	Homo sapiens	0-6
32520202-0	2020	lncRNA PCGEM1 strengthens anti-inflammatory and lung protective effects of montelukast sodium in children with cough-variant asthma.	montelukast	75-93	PCGEM1 prostate-specific transcript	Homo sapiens	7-13
25619388-0	2015	gamma-Oryzanol reduces caveolin-1 and PCGEM1 expression, markers of aggressiveness in prostate cancer cell lines.	gamma-oryzanol	0-14	PCGEM1 prostate-specific transcript	Homo sapiens	38-44
25619388-4	2015	There are evidences showing that some of the components of gamma-oryzanol can modulate genes involved in the development and progression of prostate cancer, as caveolin-1 (Cav-1) and prostate specific androgen-regulated gene (PCGEM1).	gamma-oryzanol	59-73	PCGEM1 prostate-specific transcript	Homo sapiens	226-232
25512540-5	2014	PCGEM1 promotes glucose uptake for aerobic glycolysis, coupling with the pentose phosphate shunt to facilitate biosynthesis of nucleotide and lipid, and generates NADPH for redox homeostasis.	Pentosephosphates	73-90	PCGEM1 prostate-specific transcript	Homo sapiens	0-6
25512540-5	2014	PCGEM1 promotes glucose uptake for aerobic glycolysis, coupling with the pentose phosphate shunt to facilitate biosynthesis of nucleotide and lipid, and generates NADPH for redox homeostasis.	NADP	163-168	PCGEM1 prostate-specific transcript	Homo sapiens	0-6
25512540-6	2014	We show that PCGEM1 regulates metabolism at a transcriptional level that affects multiple metabolic pathways, including glucose and glutamine metabolism, the pentose phosphate pathway, nucleotide and fatty acid biosynthesis, and the tricarboxylic acid cycle.	Glucose	120-127	PCGEM1 prostate-specific transcript	Homo sapiens	13-19
25512540-6	2014	We show that PCGEM1 regulates metabolism at a transcriptional level that affects multiple metabolic pathways, including glucose and glutamine metabolism, the pentose phosphate pathway, nucleotide and fatty acid biosynthesis, and the tricarboxylic acid cycle.	Glutamine	132-141	PCGEM1 prostate-specific transcript	Homo sapiens	13-19
25512540-6	2014	We show that PCGEM1 regulates metabolism at a transcriptional level that affects multiple metabolic pathways, including glucose and glutamine metabolism, the pentose phosphate pathway, nucleotide and fatty acid biosynthesis, and the tricarboxylic acid cycle.	Pentosephosphates	158-175	PCGEM1 prostate-specific transcript	Homo sapiens	13-19
25512540-6	2014	We show that PCGEM1 regulates metabolism at a transcriptional level that affects multiple metabolic pathways, including glucose and glutamine metabolism, the pentose phosphate pathway, nucleotide and fatty acid biosynthesis, and the tricarboxylic acid cycle.	Fatty Acids	200-210	PCGEM1 prostate-specific transcript	Homo sapiens	13-19
25512540-6	2014	We show that PCGEM1 regulates metabolism at a transcriptional level that affects multiple metabolic pathways, including glucose and glutamine metabolism, the pentose phosphate pathway, nucleotide and fatty acid biosynthesis, and the tricarboxylic acid cycle.	Tricarboxylic Acids	233-251	PCGEM1 prostate-specific transcript	Homo sapiens	13-19
19186008-1	2009	BACKGROUND: The purpose of our study was to show the apoptotic and anti-proliferative effects of phytosterols as distinct from cholesterol effects on prostate cancer cell lines, and also their differential expression of caveolin-1, and a prostate specific gene, PCGEM1.	Phytosterols	97-109	PCGEM1 prostate-specific transcript	Homo sapiens	262-268
19186008-8	2009	We demonstrated for the first time that cholesterols upregulated the expression of PCGEM1 even in androgen-insensitive prostate cancer cell lines.	Cholesterol	40-52	PCGEM1 prostate-specific transcript	Homo sapiens	83-89
19186008-10	2009	CONCLUSIONS: Phytosterol inhibition of PCGEM1 and cell growth and the overexpression of caveolin-1, suggests that poor disease prognosis anchors on the ability of caveolin-1 to regulate downstream oncogene(s) and apoptosis genes.	Phytosterols	13-24	PCGEM1 prostate-specific transcript	Homo sapiens	39-45
19186008-12	2009	Sterol regulation of PCGEM1 expression suggests its potential as biomarker for prediction of neoplasms that would be responsive to chemoprevention by phytosterols.	Phytosterols	150-162	PCGEM1 prostate-specific transcript	Homo sapiens	21-27
16569192-4	2006	This study demonstrates that PCGEM1 overexpression in LNCaP cell culture model results in the inhibition of apoptosis induced by doxorubicin (DOX).	Doxorubicin	129-140	PCGEM1 prostate-specific transcript	Homo sapiens	29-35
16569192-4	2006	This study demonstrates that PCGEM1 overexpression in LNCaP cell culture model results in the inhibition of apoptosis induced by doxorubicin (DOX).	Doxorubicin	142-145	PCGEM1 prostate-specific transcript	Homo sapiens	29-35
16569192-5	2006	Induction of p53 and p21(Waf1/Cip1) by DOX were delayed in LNCaP cells stably overexpressing PCGEM1 (LNCaP-PCGEM1 cells) compared to control LNCaP cells.	Doxorubicin	39-42	PCGEM1 prostate-specific transcript	Homo sapiens	93-99
16569192-5	2006	Induction of p53 and p21(Waf1/Cip1) by DOX were delayed in LNCaP cells stably overexpressing PCGEM1 (LNCaP-PCGEM1 cells) compared to control LNCaP cells.	Doxorubicin	39-42	PCGEM1 prostate-specific transcript	Homo sapiens	107-113
16569192-8	2006	The inhibition of PARP cleavage by PCGEM1 overexpression was also observed in LNCaP-PCGEM1 cells incubated with etoposide and sodium selenite.	Etoposide	112-121	PCGEM1 prostate-specific transcript	Homo sapiens	35-41
16569192-8	2006	The inhibition of PARP cleavage by PCGEM1 overexpression was also observed in LNCaP-PCGEM1 cells incubated with etoposide and sodium selenite.	Etoposide	112-121	PCGEM1 prostate-specific transcript	Homo sapiens	84-90
16569192-8	2006	The inhibition of PARP cleavage by PCGEM1 overexpression was also observed in LNCaP-PCGEM1 cells incubated with etoposide and sodium selenite.	Sodium Selenite	126-141	PCGEM1 prostate-specific transcript	Homo sapiens	35-41
16569192-8	2006	The inhibition of PARP cleavage by PCGEM1 overexpression was also observed in LNCaP-PCGEM1 cells incubated with etoposide and sodium selenite.	Sodium Selenite	126-141	PCGEM1 prostate-specific transcript	Homo sapiens	84-90
16569192-9	2006	Fluorescence-Activated Cell Sorter Annexin-V analysis revealed significantly lower percentage of apoptotic cells in DOX-treated LNCaP-PCGEM1 cells compared to control LNCaP cells.	Doxorubicin	116-119	PCGEM1 prostate-specific transcript	Homo sapiens	134-140