PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
11106738-6	2000	Cisplatin-induced DSBs restored Rad51/Dmc1 foci and promoted synapsis.	Cisplatin	0-9	DNA meiotic recombinase 1	Mus musculus	38-42
11106738-6	2000	Cisplatin-induced DSBs restored Rad51/Dmc1 foci and promoted synapsis.	dsbs	18-22	DNA meiotic recombinase 1	Mus musculus	38-42
9660954-2	1998	The DMC1 protein was detected in leptotene-to-zygotene spermatocytes, when homolog pairing likely initiates.	leptotene	33-42	DNA meiotic recombinase 1	Mus musculus	4-8
9660954-2	1998	The DMC1 protein was detected in leptotene-to-zygotene spermatocytes, when homolog pairing likely initiates.	zygotene	46-54	DNA meiotic recombinase 1	Mus musculus	4-8
34936917-11	2022	The recombination markers, including DMC1 and RAD51, and crossover marker MLH1 were decreased during spermatogenesis after exposure to BDE-209.	decabromobiphenyl ether	135-142	DNA meiotic recombinase 1	Mus musculus	37-41
35001532-5	2022	Decreased expressions of germ cell proliferation-associated protein PCNA and meiosis-related protein SYCP3 induced by PTX were determined by Western blot, while MLT ameliorated this effect and increased the expressions of PCNA, SYCP3, DMC1, STRA8 and fertility-related protein of HSPA2, resulting in significantly improved spermatogenesis and sperm quality levels.	Paclitaxel	118-121	DNA meiotic recombinase 1	Mus musculus	235-239
32460033-0	2020	Meiosis-Specific C19orf57/4930432K21Rik/BRME1 Modulates Localization of RAD51 and DMC1 to DSBs in Mouse Meiotic Recombination.	1,2-di-(4-sulfamidophenyl)-4-butylpyrazolidine-3,5-dione	90-94	DNA meiotic recombinase 1	Mus musculus	82-86
31210146-7	2020	In GC-1 cells cultured in vitro, Shp2 knockdown suppressed the retinoic acid (RA)-induced phosphorylation of extracellular-regulated protein kinase (Erk) and protein kinase B (Akt/PKB) and the expression of target genes such as synaptonemal complex protein 3 (Sycp3) and Dmc1.	Tretinoin	63-76	DNA meiotic recombinase 1	Mus musculus	271-275
31210146-7	2020	In GC-1 cells cultured in vitro, Shp2 knockdown suppressed the retinoic acid (RA)-induced phosphorylation of extracellular-regulated protein kinase (Erk) and protein kinase B (Akt/PKB) and the expression of target genes such as synaptonemal complex protein 3 (Sycp3) and Dmc1.	Tretinoin	78-80	DNA meiotic recombinase 1	Mus musculus	271-275
31682623-5	2019	MEK1/2 inhibitor (U0126) treatment suppressed the mRNA expressions of RA-induced Stra8 and meiotic marker genes (Rec8, Spo11, Dmc1, and Sycp3) in both XX and XY fetal germ cells.	U 0126	18-23	DNA meiotic recombinase 1	Mus musculus	126-130
31682623-5	2019	MEK1/2 inhibitor (U0126) treatment suppressed the mRNA expressions of RA-induced Stra8 and meiotic marker genes (Rec8, Spo11, Dmc1, and Sycp3) in both XX and XY fetal germ cells.	Tretinoin	70-72	DNA meiotic recombinase 1	Mus musculus	126-130
30668564-5	2019	From leptotene to early pachytene, exogenous damage triggered the massive presence of gammaH2AX throughout the nucleus, which was associated with DNA repair mediated by HR components (DMC1 and RAD51).	pachytene	24-33	DNA meiotic recombinase 1	Mus musculus	184-188
30592461-4	2018	A single injection of chemotherapeutic drug cisplatin increased frequency of RPA and DMC1 foci at the zygotene stage of sterile hybrids, enhanced homolog recognition and increased the proportion of spermatocytes with fully synapsed homologs at pachytene.	Cisplatin	44-53	DNA meiotic recombinase 1	Mus musculus	85-89
32212460-12	2018	The expressions of the spermatocyte markers DMC1 and SYCP3 were markedly lower in the model control than in the high- and low-dose QP groups (P < 0.05 or P < 0.01), and higher in the high-dose than in the low-dose QP group (P < 0.05 or P < 0.01).	SCHEMBL5970696	131-133	DNA meiotic recombinase 1	Mus musculus	44-48
27480068-2	2016	Experiments in extensive species of eukaryotes have indicated the independent role of DMC1 in repairing double strand breaks (DSBs) produced during meiosis I. Mutation of dmc1 in mice and human often leads to obstacles in spermatogenesis and male sterility.	dsbs	126-130	DNA meiotic recombinase 1	Mus musculus	171-175
26440409-7	2016	Conversely, DMC1 foci number is increased at pachynema, suggesting that under these experimental conditions, DSBs are likely made with delayed kinetics at zygonema.	dsbs	109-113	DNA meiotic recombinase 1	Mus musculus	12-16
23636811-5	2013	Finally, we found that RA induced Stra8, Sycp3, Dmc1, and Rec8 transcripts, promoting meiotic entry in culture also in pregonadal 10.5-dpc PGCs of both sexes.	Tretinoin	23-25	DNA meiotic recombinase 1	Mus musculus	48-52
23160479-8	2013	TgSCAR induced premature postnatal spermatogenic development, shown by increased levels of meiotic (Dmc1 and Spo11) and postmeiotic (Capza3 and Prm1) germ cell transcripts, elevated meiotic-postmeiotic germ:Sertoli cell ratios, and accelerated spermatid development.	tgscar	0-6	DNA meiotic recombinase 1	Mus musculus	100-104
21085687-8	2010	Finally, analysis of the DNA methylation state of the Dmc1, Paqr6, and Rims3 promoters by bisulfite sequencing revealed that these genes are highly methylated in Sp3wt MEFs but are unmethylated in Sp3E(553)D MEFs linking SUMOylation of Sp3 to tissue-specific CpG methylation.	hydrogen sulfite	90-99	DNA meiotic recombinase 1	Mus musculus	54-58
16236763-2	2005	In mammals, HR requires the activities of the RAD51 family (RAD51, RAD51B, RAD51C, RAD51D, XRCC2, XRCC3 and DMC1), each of which contains conserved ATP binding sequences (Walker Motifs A and B).	Adenosine Triphosphate	148-151	DNA meiotic recombinase 1	Mus musculus	108-112