PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
30629404-6	2019	Focusing on amino acid positions and chemical features, we first analyzed dephosphorylation of the peptide pTyr residues within the microarrayed library by the human dual-specificity phosphatases (DUSP) DUSP14 and DUSP22, as well as by PTPases from poxviruses (VH1) and Yersinia pestis (YopH).	Phosphotyrosine	107-111	dual specificity phosphatase 22	Homo sapiens	214-220
15138252-2	2004	Similar to VHR-related MKPX (VHX) (DUSP22), the predicted protein has an N-terminal myristoylation recognition sequence, and we show here that both are indeed modified by the attachment of a myristate to Gly-2.	Glycine	204-207	dual specificity phosphatase 22	Homo sapiens	11-27
15138252-2	2004	Similar to VHR-related MKPX (VHX) (DUSP22), the predicted protein has an N-terminal myristoylation recognition sequence, and we show here that both are indeed modified by the attachment of a myristate to Gly-2.	Glycine	204-207	dual specificity phosphatase 22	Homo sapiens	29-32
15138252-2	2004	Similar to VHR-related MKPX (VHX) (DUSP22), the predicted protein has an N-terminal myristoylation recognition sequence, and we show here that both are indeed modified by the attachment of a myristate to Gly-2.	Glycine	204-207	dual specificity phosphatase 22	Homo sapiens	35-41
33053837-4	2020	In this study, DUSP22 is used to investigate the importance of the DPN-triloop interaction in active site formation.	NAD	67-70	dual specificity phosphatase 22	Homo sapiens	15-21
30093402-7	2018	DUSP22-rearranged ALCLs also overexpressed immunogenic cancer-testis antigen (CTA) genes and showed marked DNA hypomethylation by reduced representation bisulfate sequencing and DNA methylation arrays.	hydrogen sulfate	153-162	dual specificity phosphatase 22	Homo sapiens	0-6
29544137-8	2018	Among the top five DMRs ranked by the lowest P-values that were associated with exposure to PFOS and PFOA, in addition to ZFP57, DMRs in the CYP2E1, SMAD3, SLC17A9, GFPT2, DUSP22, and TCERG1L genes showed the same direction of effect in the replication cohort.	perfluorooctane sulfonic acid	92-96	dual specificity phosphatase 22	Homo sapiens	172-178
29544137-8	2018	Among the top five DMRs ranked by the lowest P-values that were associated with exposure to PFOS and PFOA, in addition to ZFP57, DMRs in the CYP2E1, SMAD3, SLC17A9, GFPT2, DUSP22, and TCERG1L genes showed the same direction of effect in the replication cohort.	perfluorooctanoic acid	101-105	dual specificity phosphatase 22	Homo sapiens	172-178
22796920-0	2012	Hypomethylation of dual specificity phosphatase 22 promoter correlates with duration of service in firefighters and is inducible by low-dose benzo[a]pyrene.	Benzo(a)pyrene	141-155	dual specificity phosphatase 22	Homo sapiens	19-50
25664796-0	2015	Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate.	Phosphotyrosine	78-93	dual specificity phosphatase 22	Homo sapiens	29-60
24721094-5	2014	After precipitation with ethanol at final concentration of 40%, 60% and 80% in turn, three polysaccharide fractions of JSP1, JSP2 and JSP3 were obtained from JSP, respectively.	Polysaccharides	91-105	dual specificity phosphatase 22	Homo sapiens	119-123
20018849-4	2010	JKAP efficiently removed tyrosine phosphorylation of several proteins.	Tyrosine	25-33	dual specificity phosphatase 22	Homo sapiens	0-4
20018849-6	2010	Overexpression of JKAP, but not JKAP mutant lacking catalytic activity, decreased FAK phosphorylation at tyrosines 397, 576, and 577 in H1299 cells.	Tyrosine	105-114	dual specificity phosphatase 22	Homo sapiens	18-22
17303416-0	2007	Quinoxalinylurea derivatives as a novel class of JSP-1 inhibitors.	quinoxalinylurea	0-16	dual specificity phosphatase 22	Homo sapiens	49-54
17384676-0	2007	DUSP22/LMW-DSP2 regulates estrogen receptor-alpha-mediated signaling through dephosphorylation of Ser-118.	Serine	98-101	dual specificity phosphatase 22	Homo sapiens	0-6
17384676-0	2007	DUSP22/LMW-DSP2 regulates estrogen receptor-alpha-mediated signaling through dephosphorylation of Ser-118.	Serine	98-101	dual specificity phosphatase 22	Homo sapiens	7-15
17384676-2	2007	In this study, we show beta-estradiol (E2)-induced DUSP22 mRNA expression in estrogen receptor alpha (ERalpha)-positive breast cancer cells, whereas E2-induced phosphorylation and activation of ERalpha was suppressed by overexpression of DUSP22 but not catalytically inactive mutants.	Estradiol	23-37	dual specificity phosphatase 22	Homo sapiens	51-57
17384676-2	2007	In this study, we show beta-estradiol (E2)-induced DUSP22 mRNA expression in estrogen receptor alpha (ERalpha)-positive breast cancer cells, whereas E2-induced phosphorylation and activation of ERalpha was suppressed by overexpression of DUSP22 but not catalytically inactive mutants.	Estradiol	23-37	dual specificity phosphatase 22	Homo sapiens	238-244
17303416-1	2007	A series of quinoxalinylurea-based inhibitors are synthesized and shown to be the novel and potent inhibitors against Jnk Stimulatory Phosphatase-1 (JSP-1), which is a special member of dual-specificity protein phosphatase (DSP) family.	quinoxalinylurea	12-28	dual specificity phosphatase 22	Homo sapiens	118-147
17303416-1	2007	A series of quinoxalinylurea-based inhibitors are synthesized and shown to be the novel and potent inhibitors against Jnk Stimulatory Phosphatase-1 (JSP-1), which is a special member of dual-specificity protein phosphatase (DSP) family.	quinoxalinylurea	12-28	dual specificity phosphatase 22	Homo sapiens	149-154
17068812-5	2007	In the binary complex structure of JSP-1 with MES, the conformations of three important segments in regard to the catalytic mechanism are not similar to those in PTP1B.	2-(N-morpholino)ethanesulfonic acid	46-49	dual specificity phosphatase 22	Homo sapiens	35-40
17068812-6	2007	JSP-1 has no loop corresponding to the Lys120-loop of PTP1B, and tryptophan residue corresponding to the substrate-stacking in PTP1B is substituted by alanine residue in JSP-1.	Alanine	151-158	dual specificity phosphatase 22	Homo sapiens	0-5
17068812-6	2007	JSP-1 has no loop corresponding to the Lys120-loop of PTP1B, and tryptophan residue corresponding to the substrate-stacking in PTP1B is substituted by alanine residue in JSP-1.	Alanine	151-158	dual specificity phosphatase 22	Homo sapiens	170-175
18007403-0	2006	Preparation of 6-substituted quinoxaline JSP-1 inhibitors by microwave accelerated nucleophilic substitution.	6-substituted quinoxaline	15-40	dual specificity phosphatase 22	Homo sapiens	41-46
15961311-0	2005	Rhodanine derivatives as inhibitors of JSP-1.	Rhodanine	0-9	dual specificity phosphatase 22	Homo sapiens	39-44
15961311-2	2005	A series of rhodanine-based inhibitors was synthesized and shown to be novel, potent, and selective inhibitors against the DSP family member JNK-stimulating phosphatase-1 (JSP-1).	Rhodanine	12-21	dual specificity phosphatase 22	Homo sapiens	141-170
15961311-2	2005	A series of rhodanine-based inhibitors was synthesized and shown to be novel, potent, and selective inhibitors against the DSP family member JNK-stimulating phosphatase-1 (JSP-1).	Rhodanine	12-21	dual specificity phosphatase 22	Homo sapiens	172-177