PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 34996504-3 2022 METHODS: We performed RNA sequencing (RNA-seq) on samples from patients who were resistant or sensitive to nab-paclitaxel, and identified Zinc Finger Protein 64 (ZFP64) as critical for nab-paclitaxel resistance in GC. nab 107-110 ZFP64 zinc finger protein Homo sapiens 138-160 35219791-10 2022 Notably, Go6976, a protein kinase inhibitor, and lenvatinib, a multi-kinase inhibitor, reset the tumor microenvironment and restore sensitivity to anti-PD1 by blocking the PKCalpha/ZFP64/CSF1 axis. Go 6976 9-15 ZFP64 zinc finger protein Homo sapiens 181-186 35219791-10 2022 Notably, Go6976, a protein kinase inhibitor, and lenvatinib, a multi-kinase inhibitor, reset the tumor microenvironment and restore sensitivity to anti-PD1 by blocking the PKCalpha/ZFP64/CSF1 axis. lenvatinib 49-59 ZFP64 zinc finger protein Homo sapiens 181-186 35219791-11 2022 CONCLUSIONS: We propose that PKCalpha/ZFP64/CSF1 axis is critical for triggering immune evasion and anti-PD1 tolerance, and that inhibiting this axis with Go6976 or lenvatinib overcame anti-PD1 resistance in HCC. Go 6976 155-161 ZFP64 zinc finger protein Homo sapiens 38-43 35219791-11 2022 CONCLUSIONS: We propose that PKCalpha/ZFP64/CSF1 axis is critical for triggering immune evasion and anti-PD1 tolerance, and that inhibiting this axis with Go6976 or lenvatinib overcame anti-PD1 resistance in HCC. lenvatinib 165-175 ZFP64 zinc finger protein Homo sapiens 38-43 34996504-3 2022 METHODS: We performed RNA sequencing (RNA-seq) on samples from patients who were resistant or sensitive to nab-paclitaxel, and identified Zinc Finger Protein 64 (ZFP64) as critical for nab-paclitaxel resistance in GC. nab 185-188 ZFP64 zinc finger protein Homo sapiens 138-160 34996504-3 2022 METHODS: We performed RNA sequencing (RNA-seq) on samples from patients who were resistant or sensitive to nab-paclitaxel, and identified Zinc Finger Protein 64 (ZFP64) as critical for nab-paclitaxel resistance in GC. nab 185-188 ZFP64 zinc finger protein Homo sapiens 162-167 34996504-3 2022 METHODS: We performed RNA sequencing (RNA-seq) on samples from patients who were resistant or sensitive to nab-paclitaxel, and identified Zinc Finger Protein 64 (ZFP64) as critical for nab-paclitaxel resistance in GC. Paclitaxel 189-199 ZFP64 zinc finger protein Homo sapiens 138-160 34996504-3 2022 METHODS: We performed RNA sequencing (RNA-seq) on samples from patients who were resistant or sensitive to nab-paclitaxel, and identified Zinc Finger Protein 64 (ZFP64) as critical for nab-paclitaxel resistance in GC. nab 107-110 ZFP64 zinc finger protein Homo sapiens 162-167 34996504-3 2022 METHODS: We performed RNA sequencing (RNA-seq) on samples from patients who were resistant or sensitive to nab-paclitaxel, and identified Zinc Finger Protein 64 (ZFP64) as critical for nab-paclitaxel resistance in GC. Paclitaxel 189-199 ZFP64 zinc finger protein Homo sapiens 162-167 34996504-3 2022 METHODS: We performed RNA sequencing (RNA-seq) on samples from patients who were resistant or sensitive to nab-paclitaxel, and identified Zinc Finger Protein 64 (ZFP64) as critical for nab-paclitaxel resistance in GC. Paclitaxel 111-121 ZFP64 zinc finger protein Homo sapiens 138-160 34996504-3 2022 METHODS: We performed RNA sequencing (RNA-seq) on samples from patients who were resistant or sensitive to nab-paclitaxel, and identified Zinc Finger Protein 64 (ZFP64) as critical for nab-paclitaxel resistance in GC. Paclitaxel 111-121 ZFP64 zinc finger protein Homo sapiens 162-167 33054540-9 2021 However, Notch inhibitor MK-0752 inhibited the effects of overexpressed ZFP64 on H1975 cell viability, cell cycle, migration, EMT progress, and Notch pathway activation. 3-(4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid 25-32 ZFP64 zinc finger protein Homo sapiens 72-77