PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
31042033-0	2019	Reaction Mechanism for the N-Glycosidic Bond Cleavage of 5-Formylcytosine by Thymine DNA Glycosylase.	5-formylcytosine	57-73	thymine DNA glycosylase	Mus musculus	77-100
32268085-6	2020	These results indicate that TDG functions as a tumor suppressor of HCC by regulating a transcriptional program that protects against the development of glucose intolerance and BA accumulation in the liver.	Bile Acids and Salts	176-178	thymine DNA glycosylase	Mus musculus	28-31
31042033-1	2019	Thymine DNA glycosylase (TDG) initiates the base excision repair mechanism for the deamination and oxidation products of cytosine and 5-methylcytosine.	Cytosine	121-129	thymine DNA glycosylase	Mus musculus	0-23
31042033-1	2019	Thymine DNA glycosylase (TDG) initiates the base excision repair mechanism for the deamination and oxidation products of cytosine and 5-methylcytosine.	Cytosine	121-129	thymine DNA glycosylase	Mus musculus	25-28
31042033-1	2019	Thymine DNA glycosylase (TDG) initiates the base excision repair mechanism for the deamination and oxidation products of cytosine and 5-methylcytosine.	5-Methylcytosine	134-150	thymine DNA glycosylase	Mus musculus	0-23
31042033-1	2019	Thymine DNA glycosylase (TDG) initiates the base excision repair mechanism for the deamination and oxidation products of cytosine and 5-methylcytosine.	5-Methylcytosine	134-150	thymine DNA glycosylase	Mus musculus	25-28
29382419-8	2017	Furthermore, only by a high concentration of alpinetin (1 000 mug/mL), could the synthesis of TDG mRNA be promoted, yet the synthesis of DNMT3alpha and EZH2 were not influenced.	alpinetin	45-54	thymine DNA glycosylase	Mus musculus	94-97
30674989-7	2019	Candidate TDG inhibitors, identified through a high-throughput fluorescence-based screen, reduced viability and clonogenic capacity of melanoma cell lines and increased cellular levels of 5-carboxylcytosine, the last intermediate in DNA demethylation, indicating successful on-target activity.	5-carboxylcytosine	188-206	thymine DNA glycosylase	Mus musculus	10-13
30523148-1	2019	During active DNA demethylation, 5-methylcytosine (5mC) is oxidized by TET proteins to 5-formyl-/5-carboxylcytosine (5fC/5caC) for replacement by unmethylated C by TDG-initiated DNA base excision repair (BER).	5-Methylcytosine	33-49	thymine DNA glycosylase	Mus musculus	164-167
30523148-1	2019	During active DNA demethylation, 5-methylcytosine (5mC) is oxidized by TET proteins to 5-formyl-/5-carboxylcytosine (5fC/5caC) for replacement by unmethylated C by TDG-initiated DNA base excision repair (BER).	5-Methylcytosine	51-54	thymine DNA glycosylase	Mus musculus	164-167
30523148-1	2019	During active DNA demethylation, 5-methylcytosine (5mC) is oxidized by TET proteins to 5-formyl-/5-carboxylcytosine (5fC/5caC) for replacement by unmethylated C by TDG-initiated DNA base excision repair (BER).	5-formyl-/5-carboxylcytosine	87-115	thymine DNA glycosylase	Mus musculus	164-167
30523148-5	2019	Within this TDG-BERosome, SUMO is transferred from XRCC1 and coupled to the SUMO acceptor lysine in TDG, promoting its dissociation while assuring the engagement of the BER machinery to complete demethylation.	Lysine	90-96	thymine DNA glycosylase	Mus musculus	12-15
30523148-5	2019	Within this TDG-BERosome, SUMO is transferred from XRCC1 and coupled to the SUMO acceptor lysine in TDG, promoting its dissociation while assuring the engagement of the BER machinery to complete demethylation.	Lysine	90-96	thymine DNA glycosylase	Mus musculus	100-103
27356509-1	2016	BACKGROUND: Genome-wide methylation of cytosine can be modulated in the presence of TET and thymine DNA glycosylase (TDG) enzymes.	Cytosine	39-47	thymine DNA glycosylase	Mus musculus	92-115
29163805-2	2017	In addition, TDG has an epigenomic function by removing the novel cytosine derivatives 5-formylcytosine and 5-carboxylcytosine (5caC) generated by Ten-Eleven Translocation (TET) enzymes during active DNA demethylation.	Cytosine	66-74	thymine DNA glycosylase	Mus musculus	13-16
29163805-2	2017	In addition, TDG has an epigenomic function by removing the novel cytosine derivatives 5-formylcytosine and 5-carboxylcytosine (5caC) generated by Ten-Eleven Translocation (TET) enzymes during active DNA demethylation.	5-formylcytosine	87-103	thymine DNA glycosylase	Mus musculus	13-16
29163805-2	2017	In addition, TDG has an epigenomic function by removing the novel cytosine derivatives 5-formylcytosine and 5-carboxylcytosine (5caC) generated by Ten-Eleven Translocation (TET) enzymes during active DNA demethylation.	5-carboxylcytosine	108-126	thymine DNA glycosylase	Mus musculus	13-16
27951654-3	2016	We demonstrate that TDG interacts with the CH3 domain of p300 to allosterically promote p300 activity to specific lysines on histone H3 (K18 and K23).	Lysine	114-121	thymine DNA glycosylase	Mus musculus	20-23
27713569-0	2016	Dioxin induces Ahr-dependent robust DNA demethylation of the Cyp1a1 promoter via Tdg in the mouse liver.	Dioxins	0-6	thymine DNA glycosylase	Mus musculus	81-84
27713569-5	2016	A single dose of TCDD administered to adult mice induced Ahr-dependent CpG hypomethylation, changes in histone modifications, and thymine DNA glycosylase (Tdg) recruitment at the Cyp1a1 promoter in the liver within 24 hrs.	Polychlorinated Dibenzodioxins	17-21	thymine DNA glycosylase	Mus musculus	130-153
27713569-5	2016	A single dose of TCDD administered to adult mice induced Ahr-dependent CpG hypomethylation, changes in histone modifications, and thymine DNA glycosylase (Tdg) recruitment at the Cyp1a1 promoter in the liver within 24 hrs.	Polychlorinated Dibenzodioxins	17-21	thymine DNA glycosylase	Mus musculus	155-158
27713569-7	2016	Our demethylation assay using siRNA knockdown and an in vitro methylated plasmid showed that Ahr, Tdg, and the ten-eleven translocation methyldioxygenases Tet2 and Tet3 are required for the TCDD-induced DNA demethylation.	Polychlorinated Dibenzodioxins	190-194	thymine DNA glycosylase	Mus musculus	98-101
27356509-1	2016	BACKGROUND: Genome-wide methylation of cytosine can be modulated in the presence of TET and thymine DNA glycosylase (TDG) enzymes.	Cytosine	39-47	thymine DNA glycosylase	Mus musculus	117-120
27356509-1	2016	BACKGROUND: Genome-wide methylation of cytosine can be modulated in the presence of TET and thymine DNA glycosylase (TDG) enzymes.	tetramethylenedisulfotetramine	84-87	thymine DNA glycosylase	Mus musculus	117-120
27356509-7	2016	Changes in the formylation profile of cytosine upon depletion of TDG suggest TET/TDG-mediated active demethylation occurs preferentially at intron-exon boundaries and reveals a major role for TDG in shaping 5fC distribution at CpG islands.	Cytosine	38-46	thymine DNA glycosylase	Mus musculus	65-68
27356509-7	2016	Changes in the formylation profile of cytosine upon depletion of TDG suggest TET/TDG-mediated active demethylation occurs preferentially at intron-exon boundaries and reveals a major role for TDG in shaping 5fC distribution at CpG islands.	Cytosine	38-46	thymine DNA glycosylase	Mus musculus	81-84
27356509-7	2016	Changes in the formylation profile of cytosine upon depletion of TDG suggest TET/TDG-mediated active demethylation occurs preferentially at intron-exon boundaries and reveals a major role for TDG in shaping 5fC distribution at CpG islands.	Cytosine	38-46	thymine DNA glycosylase	Mus musculus	81-84
27356509-7	2016	Changes in the formylation profile of cytosine upon depletion of TDG suggest TET/TDG-mediated active demethylation occurs preferentially at intron-exon boundaries and reveals a major role for TDG in shaping 5fC distribution at CpG islands.	tetramethylenedisulfotetramine	77-80	thymine DNA glycosylase	Mus musculus	65-68
27356509-7	2016	Changes in the formylation profile of cytosine upon depletion of TDG suggest TET/TDG-mediated active demethylation occurs preferentially at intron-exon boundaries and reveals a major role for TDG in shaping 5fC distribution at CpG islands.	tetramethylenedisulfotetramine	77-80	thymine DNA glycosylase	Mus musculus	81-84
27356509-7	2016	Changes in the formylation profile of cytosine upon depletion of TDG suggest TET/TDG-mediated active demethylation occurs preferentially at intron-exon boundaries and reveals a major role for TDG in shaping 5fC distribution at CpG islands.	tetramethylenedisulfotetramine	77-80	thymine DNA glycosylase	Mus musculus	81-84
27356509-9	2016	CONCLUSIONS: The tissue-specific distribution of 5fC can be regulated by the collective contribution of TET-mediated oxidation and excision by TDG.	tetramethylenedisulfotetramine	104-107	thymine DNA glycosylase	Mus musculus	143-146
25304979-8	2015	When the TDG over-expressed oocytes were blocked at the GV stage, the oocyte chromatin became decondensed, and the histone 3 trimethyl lysine 9 (H3K9me3) and H3K9me2 levels were decreased.	trimethyllysine	125-141	thymine DNA glycosylase	Mus musculus	9-12
26889208-12	2016	Finally, we demonstrate here that ERbeta interacts with TDG and that TDG binds ERbeta-dependently to hypermethylated DMPs.	Unithiol	117-121	thymine DNA glycosylase	Mus musculus	69-72
23820384-0	2013	Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a.	tet	26-29	thymine DNA glycosylase	Mus musculus	60-63
23820384-1	2013	The ten-eleven translocation family of proteins (Tet1/2/3, Tets) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), which can be further oxidized and repaired by thymine DNA glycosylase (TDG), to influence gene transcription in embryonic and adult tissues.	tetramethylenedisulfotetramine	59-63	thymine DNA glycosylase	Mus musculus	178-201
23820384-1	2013	The ten-eleven translocation family of proteins (Tet1/2/3, Tets) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), which can be further oxidized and repaired by thymine DNA glycosylase (TDG), to influence gene transcription in embryonic and adult tissues.	tetramethylenedisulfotetramine	59-63	thymine DNA glycosylase	Mus musculus	203-206
23820384-1	2013	The ten-eleven translocation family of proteins (Tet1/2/3, Tets) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), which can be further oxidized and repaired by thymine DNA glycosylase (TDG), to influence gene transcription in embryonic and adult tissues.	5-Methylcytosine	74-90	thymine DNA glycosylase	Mus musculus	178-201
23820384-1	2013	The ten-eleven translocation family of proteins (Tet1/2/3, Tets) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), which can be further oxidized and repaired by thymine DNA glycosylase (TDG), to influence gene transcription in embryonic and adult tissues.	5-Methylcytosine	74-90	thymine DNA glycosylase	Mus musculus	203-206
23820384-1	2013	The ten-eleven translocation family of proteins (Tet1/2/3, Tets) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), which can be further oxidized and repaired by thymine DNA glycosylase (TDG), to influence gene transcription in embryonic and adult tissues.	5-Methylcytosine	92-95	thymine DNA glycosylase	Mus musculus	178-201
23820384-1	2013	The ten-eleven translocation family of proteins (Tet1/2/3, Tets) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), which can be further oxidized and repaired by thymine DNA glycosylase (TDG), to influence gene transcription in embryonic and adult tissues.	5-Methylcytosine	92-95	thymine DNA glycosylase	Mus musculus	203-206
23820384-1	2013	The ten-eleven translocation family of proteins (Tet1/2/3, Tets) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), which can be further oxidized and repaired by thymine DNA glycosylase (TDG), to influence gene transcription in embryonic and adult tissues.	5-hydroxymethylcytosine	100-123	thymine DNA glycosylase	Mus musculus	178-201
23820384-1	2013	The ten-eleven translocation family of proteins (Tet1/2/3, Tets) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), which can be further oxidized and repaired by thymine DNA glycosylase (TDG), to influence gene transcription in embryonic and adult tissues.	5-hydroxymethylcytosine	100-123	thymine DNA glycosylase	Mus musculus	203-206
23820384-1	2013	The ten-eleven translocation family of proteins (Tet1/2/3, Tets) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), which can be further oxidized and repaired by thymine DNA glycosylase (TDG), to influence gene transcription in embryonic and adult tissues.	5-hydroxymethylcytosine	125-129	thymine DNA glycosylase	Mus musculus	178-201
23820384-1	2013	The ten-eleven translocation family of proteins (Tet1/2/3, Tets) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), which can be further oxidized and repaired by thymine DNA glycosylase (TDG), to influence gene transcription in embryonic and adult tissues.	5-hydroxymethylcytosine	125-129	thymine DNA glycosylase	Mus musculus	203-206
23602152-0	2013	Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics.	5-Methylcytosine	52-68	thymine DNA glycosylase	Mus musculus	38-41
22902005-3	2012	Recent advances have identified key players involved in active demethylation pathways, including oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) by the TET enzymes, and excision of 5fC by the base excision repair enzyme thymine DNA glycosylase (TDG).	tetramethylenedisulfotetramine	182-185	thymine DNA glycosylase	Mus musculus	275-278
22902005-0	2012	Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase.	5-formylcytosine	28-44	thymine DNA glycosylase	Mus musculus	117-140
22124233-2	2011	Interestingly, recent studies have shown that 5hmC can be further oxidized by Tet proteins to generate 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), which can be removed by thymine DNA glycosylase (TDG).	5-hydroxymethylcytosine	46-50	thymine DNA glycosylase	Mus musculus	181-204
22902005-3	2012	Recent advances have identified key players involved in active demethylation pathways, including oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) by the TET enzymes, and excision of 5fC by the base excision repair enzyme thymine DNA glycosylase (TDG).	5-Methylcytidine 5'-monophosphate	110-113	thymine DNA glycosylase	Mus musculus	250-273
22902005-3	2012	Recent advances have identified key players involved in active demethylation pathways, including oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) by the TET enzymes, and excision of 5fC by the base excision repair enzyme thymine DNA glycosylase (TDG).	5-Methylcytidine 5'-monophosphate	110-113	thymine DNA glycosylase	Mus musculus	275-278
22902005-3	2012	Recent advances have identified key players involved in active demethylation pathways, including oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) by the TET enzymes, and excision of 5fC by the base excision repair enzyme thymine DNA glycosylase (TDG).	5-hydroxymethylcytosine	117-140	thymine DNA glycosylase	Mus musculus	250-273
22902005-3	2012	Recent advances have identified key players involved in active demethylation pathways, including oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) by the TET enzymes, and excision of 5fC by the base excision repair enzyme thymine DNA glycosylase (TDG).	5-hydroxymethylcytosine	117-140	thymine DNA glycosylase	Mus musculus	275-278
22902005-3	2012	Recent advances have identified key players involved in active demethylation pathways, including oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) by the TET enzymes, and excision of 5fC by the base excision repair enzyme thymine DNA glycosylase (TDG).	5-hydroxymethylcytosine	142-146	thymine DNA glycosylase	Mus musculus	250-273
22902005-3	2012	Recent advances have identified key players involved in active demethylation pathways, including oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) by the TET enzymes, and excision of 5fC by the base excision repair enzyme thymine DNA glycosylase (TDG).	5-hydroxymethylcytosine	142-146	thymine DNA glycosylase	Mus musculus	275-278
22902005-3	2012	Recent advances have identified key players involved in active demethylation pathways, including oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) by the TET enzymes, and excision of 5fC by the base excision repair enzyme thymine DNA glycosylase (TDG).	5-formylcytosine	152-168	thymine DNA glycosylase	Mus musculus	250-273
22902005-3	2012	Recent advances have identified key players involved in active demethylation pathways, including oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) by the TET enzymes, and excision of 5fC by the base excision repair enzyme thymine DNA glycosylase (TDG).	5-formylcytosine	152-168	thymine DNA glycosylase	Mus musculus	275-278
22902005-3	2012	Recent advances have identified key players involved in active demethylation pathways, including oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) by the TET enzymes, and excision of 5fC by the base excision repair enzyme thymine DNA glycosylase (TDG).	tetramethylenedisulfotetramine	182-185	thymine DNA glycosylase	Mus musculus	250-273
22200605-0	2012	Embryonic lethality in mice lacking mismatch-specific thymine DNA glycosylase is partially prevented by DOPS, a precursor of noradrenaline.	Droxidopa	104-108	thymine DNA glycosylase	Mus musculus	54-77
22200605-0	2012	Embryonic lethality in mice lacking mismatch-specific thymine DNA glycosylase is partially prevented by DOPS, a precursor of noradrenaline.	Norepinephrine	125-138	thymine DNA glycosylase	Mus musculus	54-77
22200605-1	2012	Thymine DNA glycosylase (TDG) is involved in the repair of G:T and G:U mismatches caused by hydrolytic deamination of 5-methylcytosine and cytosine, respectively.	5-Methylcytosine	118-134	thymine DNA glycosylase	Mus musculus	0-23
22200605-1	2012	Thymine DNA glycosylase (TDG) is involved in the repair of G:T and G:U mismatches caused by hydrolytic deamination of 5-methylcytosine and cytosine, respectively.	5-Methylcytosine	118-134	thymine DNA glycosylase	Mus musculus	25-28
22200605-1	2012	Thymine DNA glycosylase (TDG) is involved in the repair of G:T and G:U mismatches caused by hydrolytic deamination of 5-methylcytosine and cytosine, respectively.	Cytosine	126-134	thymine DNA glycosylase	Mus musculus	0-23
22200605-1	2012	Thymine DNA glycosylase (TDG) is involved in the repair of G:T and G:U mismatches caused by hydrolytic deamination of 5-methylcytosine and cytosine, respectively.	Cytosine	126-134	thymine DNA glycosylase	Mus musculus	25-28
22200605-5	2012	On the other hand, the levels of noradrenaline in 10.5 dpc whole embryos, which is necessary for normal embryogenesis, were dramatically reduced in Tdg (-/-) embryos.	Norepinephrine	33-46	thymine DNA glycosylase	Mus musculus	148-151
22200605-6	2012	Consequently, we tested the effect of D, L-threo-3, 4-dihydroxyphenylserine (DOPS), a synthetic precursor of noradrenaline, on the survival of the Tdg (-/-) embryos.	d, l-threo-3, 4-dihydroxyphenylserine	38-75	thymine DNA glycosylase	Mus musculus	147-150
22200605-6	2012	Consequently, we tested the effect of D, L-threo-3, 4-dihydroxyphenylserine (DOPS), a synthetic precursor of noradrenaline, on the survival of the Tdg (-/-) embryos.	Droxidopa	77-81	thymine DNA glycosylase	Mus musculus	147-150
22200605-7	2012	DOPS was given to pregnant Tdg (+/-) mice from 6.5 dpc through drinking water.	Droxidopa	0-4	thymine DNA glycosylase	Mus musculus	27-30
22200605-8	2012	Most of the Tdg (-/-) embryos were alive at 11.5 dpc, and they were partially rescued up to 14.5 dpc by the administration of DOPS.	Droxidopa	126-130	thymine DNA glycosylase	Mus musculus	12-15
22200605-9	2012	In contrast, the administration of L-3, 4-dihydroxyphenylalanine (L-DOPA) had marginal effects on Tdg (-/-) embryonic lethality.	Levodopa	35-64	thymine DNA glycosylase	Mus musculus	98-101
22200605-9	2012	In contrast, the administration of L-3, 4-dihydroxyphenylalanine (L-DOPA) had marginal effects on Tdg (-/-) embryonic lethality.	Levodopa	66-72	thymine DNA glycosylase	Mus musculus	98-101
22200605-11	2012	These results suggest that embryonic lethality in Tdg (-/-) embryos is due, in part, to the reduction of noradrenaline levels.	Norepinephrine	105-118	thymine DNA glycosylase	Mus musculus	50-53
22124233-2	2011	Interestingly, recent studies have shown that 5hmC can be further oxidized by Tet proteins to generate 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), which can be removed by thymine DNA glycosylase (TDG).	5-hydroxymethylcytosine	46-50	thymine DNA glycosylase	Mus musculus	206-209
22124233-2	2011	Interestingly, recent studies have shown that 5hmC can be further oxidized by Tet proteins to generate 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), which can be removed by thymine DNA glycosylase (TDG).	tetramethylenedisulfotetramine	78-81	thymine DNA glycosylase	Mus musculus	181-204
22124233-2	2011	Interestingly, recent studies have shown that 5hmC can be further oxidized by Tet proteins to generate 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), which can be removed by thymine DNA glycosylase (TDG).	tetramethylenedisulfotetramine	78-81	thymine DNA glycosylase	Mus musculus	206-209
22124233-2	2011	Interestingly, recent studies have shown that 5hmC can be further oxidized by Tet proteins to generate 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), which can be removed by thymine DNA glycosylase (TDG).	5-formylcytosine	103-119	thymine DNA glycosylase	Mus musculus	181-204
22124233-2	2011	Interestingly, recent studies have shown that 5hmC can be further oxidized by Tet proteins to generate 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), which can be removed by thymine DNA glycosylase (TDG).	5-formylcytosine	103-119	thymine DNA glycosylase	Mus musculus	206-209
22124233-2	2011	Interestingly, recent studies have shown that 5hmC can be further oxidized by Tet proteins to generate 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), which can be removed by thymine DNA glycosylase (TDG).	5-carboxylcytosine	130-148	thymine DNA glycosylase	Mus musculus	181-204
22124233-2	2011	Interestingly, recent studies have shown that 5hmC can be further oxidized by Tet proteins to generate 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), which can be removed by thymine DNA glycosylase (TDG).	5-carboxylcytosine	130-148	thymine DNA glycosylase	Mus musculus	206-209
7604398-6	1995	To explore the generality of this effect in vesicant action, we measured the protein serine/threonine phosphatase activity in mouse liver cytosol (in the form of the okadaic acid inhibitable increment of p-nitrophenyl phosphate (p-NPP) phosphatase activity) in the presence of aqueous sulfur mustard or its hydrolysis product, bis(hydroxyethyl)sulfide (TDG).	Okadaic Acid	166-178	thymine DNA glycosylase	Mus musculus	353-356
19402749-4	2009	Using genetic and biochemical tools, we found that inactivation of TDG significantly increases resistance of both mouse and human cancer cells towards 5-FU.	Fluorouracil	151-155	thymine DNA glycosylase	Mus musculus	67-70
16417912-1	2006	Thiodiglycol (2,2"-bis-hydroxyethylsulfide, TDG), the hydrolysis product of the chemical warfare agent sulfur mustard, has been implicated in the toxicity of sulfur mustard through the inhibition of protein phosphatases in mouse liver cytosol.	2,2'-thiodiethanol	0-12	thymine DNA glycosylase	Mus musculus	44-47
16417912-1	2006	Thiodiglycol (2,2"-bis-hydroxyethylsulfide, TDG), the hydrolysis product of the chemical warfare agent sulfur mustard, has been implicated in the toxicity of sulfur mustard through the inhibition of protein phosphatases in mouse liver cytosol.	Mustard Gas	103-117	thymine DNA glycosylase	Mus musculus	44-47
16417912-1	2006	Thiodiglycol (2,2"-bis-hydroxyethylsulfide, TDG), the hydrolysis product of the chemical warfare agent sulfur mustard, has been implicated in the toxicity of sulfur mustard through the inhibition of protein phosphatases in mouse liver cytosol.	Mustard Gas	158-172	thymine DNA glycosylase	Mus musculus	44-47
7604398-9	1995	TDG exhibited a direct, concentration-related inhibition of p-NPP hydrolysis between 30 and 300 microM.	nitrophenylphosphate	60-65	thymine DNA glycosylase	Mus musculus	0-3
35285483-7	2022	Expression of each member of the Tet3/Uhrf2/Tdg active demethylation pathway was reduced in Uhrf2-deficient retinae, consistent with locally reduced 5hmC in their gene bodies.	5-hydroxymethylcytosine	149-153	thymine DNA glycosylase	Mus musculus	44-47