PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
34118875-0	2021	beta-elemene alleviates airway stenosis via the ILK/Akt pathway modulated by MIR143HG sponging miR-1275.	beta-elemene	0-12	microRNA 1275	Homo sapiens	95-103
34118875-6	2021	RESULTS: The hyperactive ILK/Akt pathway and dysregulated LncRNA-MIR143HG, which acted as a miR-1275 ceRNA to modulate ILK expression, were suppressed in beta-elemene-treated airway granulation fibroblasts; beta-elemene suppressed the ILK/Akt pathway via the MIR143HG/miR-1275/ILK axis.	beta-elemene	154-166	microRNA 1275	Homo sapiens	92-100
34118875-6	2021	RESULTS: The hyperactive ILK/Akt pathway and dysregulated LncRNA-MIR143HG, which acted as a miR-1275 ceRNA to modulate ILK expression, were suppressed in beta-elemene-treated airway granulation fibroblasts; beta-elemene suppressed the ILK/Akt pathway via the MIR143HG/miR-1275/ILK axis.	beta-elemene	154-166	microRNA 1275	Homo sapiens	268-276
34118875-6	2021	RESULTS: The hyperactive ILK/Akt pathway and dysregulated LncRNA-MIR143HG, which acted as a miR-1275 ceRNA to modulate ILK expression, were suppressed in beta-elemene-treated airway granulation fibroblasts; beta-elemene suppressed the ILK/Akt pathway via the MIR143HG/miR-1275/ILK axis.	elemene	211-219	microRNA 1275	Homo sapiens	92-100
34118875-6	2021	RESULTS: The hyperactive ILK/Akt pathway and dysregulated LncRNA-MIR143HG, which acted as a miR-1275 ceRNA to modulate ILK expression, were suppressed in beta-elemene-treated airway granulation fibroblasts; beta-elemene suppressed the ILK/Akt pathway via the MIR143HG/miR-1275/ILK axis.	elemene	211-219	microRNA 1275	Homo sapiens	268-276
34118875-8	2021	In vivo application of beta-elemene attenuated airway granulation hyperplasia and alleviated scar stricture, and histological detections suggested that beta-elemene"s effects on the MIR143HG/miR-1275/ILK axis and ILK/Akt pathway were in line with in vitro findings.	beta-elemene	152-164	microRNA 1275	Homo sapiens	191-199
34118875-10	2021	The MIR143HG/miR-1275/ILK axis mediates beta-elemene-induced cell cycle arrest and apoptosis of airway granulation fibroblasts by modulating the ILK/Akt pathway, thereby inhibiting airway granulation proliferation and ultimately alleviating airway stenosis.	beta-elemene	40-52	microRNA 1275	Homo sapiens	13-21
31162799-2	2019	In this study, by performing miRNA genomics and loss- and gain-of-function assays in dibutyryl-cAMP-treated GBM cells, we identified a critical negative regulator, hsa-miR-1275, that modulates a set of genes involved in cancer progression, stem cell maintenance, and cell maturation and differentiation.	Cyclic AMP	95-99	microRNA 1275	Homo sapiens	164-176
33323026-10	2020	Inhibition of miR-1275 suppressed the increased activity of LDH and CK, cell apoptosis, reactive oxygen species (ROS) production, intracellular Ca2+ concentration and sarcoplasmic reticulum (SR) Ca2+ leak induced by OGD/R treatment in cardiomyocytes.	Reactive Oxygen Species	88-111	microRNA 1275	Homo sapiens	14-22
33323026-10	2020	Inhibition of miR-1275 suppressed the increased activity of LDH and CK, cell apoptosis, reactive oxygen species (ROS) production, intracellular Ca2+ concentration and sarcoplasmic reticulum (SR) Ca2+ leak induced by OGD/R treatment in cardiomyocytes.	Reactive Oxygen Species	113-116	microRNA 1275	Homo sapiens	14-22
31162799-4	2019	Of note, tri-methyl-histone H3 (Lys27) (H3K27me3), downstream of the PKA/polycomb repressive complex 2 (PRC2) pathway, accounts for the downregulation of miR-1275.	tri-methyl-histone	9-27	microRNA 1275	Homo sapiens	154-162
31162799-5	2019	Furthermore, decreased miR-1275 expression and induction of GFAP expression were also observed in dibutyryl-cAMP-treated primary cultured GBM cells.	Cyclic AMP	108-112	microRNA 1275	Homo sapiens	23-31
31162799-6	2019	In a patient-derived glioma stem cell tumor model, a cAMP elevator and an inhibitor of H3K27me3 methyltransferase inhibited tumor growth, induced differentiation, and reduced expression of miR-1275.	Cyclic AMP	53-57	microRNA 1275	Homo sapiens	189-197
31162799-7	2019	In summary, our study shows that epigenetic inhibition of miR-1275 by the cAMP/PKA/PRC2/H3K27me3 pathway mediates glial induction of GBM cells, providing a new mechanism and novel targets for differentiation-inducing therapy.	Cyclic AMP	74-78	microRNA 1275	Homo sapiens	58-66
31137016-5	2019	The direct binding between circ-0001649 and miR-127-5p/miR-612/miR-4688 were verified through Dual-luciferase reporter gene assay, RNA Binding Protein Immunoprecipitation (RIP) assay and western blot detection.	circ	27-31	microRNA 1275	Homo sapiens	44-54
31137016-10	2019	Furthermore, we determined that circ-0001649 served as a ceRNA to sponge miR-127-5p, miR-612 and miR-4688, thus activating SHPRH.	circ	32-36	microRNA 1275	Homo sapiens	73-83
27625050-7	2016	RESULTS: MiR-1275 and miR-1246 expression levels were up-regulated by curcumin.	Curcumin	70-78	microRNA 1275	Homo sapiens	9-17
27625050-11	2016	CONCLUSION: Collectively, our findings demonstrate that curcumin inhibited HUVEC proliferation by up-regulation of miR-1275 and miR-1246.	Curcumin	56-64	microRNA 1275	Homo sapiens	115-123