PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 32905584-4 2020 Here we show that restoration of cytosolic purine nucleotide levels rescues the constitutive autophagy phenotype of rns2-2 seedlings, whereas inhibition of purine synthesis induces autophagy in wild-type seedlings. Purine Nucleotides 43-60 ribonuclease 2 Arabidopsis thaliana 116-120 28961890-12 2017 Elevated levels of reactive oxygen species (ROS) were also measured in rns2-2, and the constitutive autophagy phenotype was blocked by preventing ROS production via NADPH oxidase. Reactive Oxygen Species 19-42 ribonuclease 2 Arabidopsis thaliana 71-75 28961890-12 2017 Elevated levels of reactive oxygen species (ROS) were also measured in rns2-2, and the constitutive autophagy phenotype was blocked by preventing ROS production via NADPH oxidase. Reactive Oxygen Species 44-47 ribonuclease 2 Arabidopsis thaliana 71-75 28961890-13 2017 Conclusions: Lack of rRNA recycling in rns2-2 cells triggers a change in carbon flux, which is redirected through the PPP to produce ribose-5-phosphate for de novo nucleoside synthesis. Carbon 73-79 ribonuclease 2 Arabidopsis thaliana 39-43 28961890-13 2017 Conclusions: Lack of rRNA recycling in rns2-2 cells triggers a change in carbon flux, which is redirected through the PPP to produce ribose-5-phosphate for de novo nucleoside synthesis. ribose-5-phosphate 133-151 ribonuclease 2 Arabidopsis thaliana 39-43 28961890-13 2017 Conclusions: Lack of rRNA recycling in rns2-2 cells triggers a change in carbon flux, which is redirected through the PPP to produce ribose-5-phosphate for de novo nucleoside synthesis. Nucleosides 164-174 ribonuclease 2 Arabidopsis thaliana 39-43 9880376-1 1999 Antisense inhibition of RNS1 or RNS2 elevates anthocyanin accumulation. Anthocyanins 46-57 ribonuclease 2 Arabidopsis thaliana 32-36 9880376-3 1999 Both RNS1 and RNS2 mRNAs have been shown previously to be induced by inorganic phosphate (Pi) starvation. Phosphates 69-88 ribonuclease 2 Arabidopsis thaliana 14-18 8506358-14 1993 Phosphate starvation can also induce the expression of RNS2. Phosphates 0-9 ribonuclease 2 Arabidopsis thaliana 55-59 8506358-15 1993 On the basis of these observations, we suggest that one role of RNS2 in Arabidopsis may be to remobilize phosphate, particularly when cells senesce or when phosphate becomes limiting. Phosphates 105-114 ribonuclease 2 Arabidopsis thaliana 64-68 8506358-15 1993 On the basis of these observations, we suggest that one role of RNS2 in Arabidopsis may be to remobilize phosphate, particularly when cells senesce or when phosphate becomes limiting. Phosphates 156-165 ribonuclease 2 Arabidopsis thaliana 64-68 32905584-4 2020 Here we show that restoration of cytosolic purine nucleotide levels rescues the constitutive autophagy phenotype of rns2-2 seedlings, whereas inhibition of purine synthesis induces autophagy in wild-type seedlings. purine 43-49 ribonuclease 2 Arabidopsis thaliana 116-120 32905584-5 2020 rns2-2 seedlings have reduced activity of the target of rapamycin (TOR) kinase complex, a negative regulator of autophagy, and this phenotype is rescued by addition of inosine to increase purine levels. Inosine 168-175 ribonuclease 2 Arabidopsis thaliana 0-4 32905584-5 2020 rns2-2 seedlings have reduced activity of the target of rapamycin (TOR) kinase complex, a negative regulator of autophagy, and this phenotype is rescued by addition of inosine to increase purine levels. purine 188-194 ribonuclease 2 Arabidopsis thaliana 0-4 32905584-6 2020 Activation of TOR in rns2-2 by exogenous auxin blocks the enhanced autophagy, indicating a possible involvement of the TOR signaling pathway in the activation of autophagy in the rns2-2 mutant. Indoleacetic Acids 41-46 ribonuclease 2 Arabidopsis thaliana 21-25 32905584-6 2020 Activation of TOR in rns2-2 by exogenous auxin blocks the enhanced autophagy, indicating a possible involvement of the TOR signaling pathway in the activation of autophagy in the rns2-2 mutant. Indoleacetic Acids 41-46 ribonuclease 2 Arabidopsis thaliana 179-183