PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 16568240-4 2006 Caveolin-1 phosphorylation at tyrosine residue 14 induces the dissociation of caveolin-1 from TCP-1 and activates actin folding. Tyrosine 30-38 t-complex 1 Homo sapiens 94-99 12502735-3 2002 Here we report that HDAC3 interacts with SMRT only after priming by cellular chaperones including the TCP-1 ring complex (TRiC), which is required for proper folding of HDAC3 in an ATP-dependent process. Adenosine Triphosphate 181-184 t-complex 1 Homo sapiens 102-107 16061661-9 2005 Small interfering RNA inhibition of FRA1, TCP1, and MCM2 expression was associated with reduced growth and FRA1 inhibition with enhanced cisplatin sensitivity. Cisplatin 137-146 t-complex 1 Homo sapiens 42-46 8573069-6 1996 The predicted HsCCT gamma amino acid sequence shares a high degree of sequence similarity with gamma-subunits from the mouse Mus musculus (98% similarity), the yeast Saccharomyces cerevisiae (75% similarity) and the protozoan Tetrahymena pyriformis (76% similarity) as well as with other members of the TF55/TCP-1 family, such as human TCP-1/CCT alpha (55% similarity) and TCP-20/CCT zeta (54% similarity). gamma amino acid 20-36 t-complex 1 Homo sapiens 308-313 11483510-3 2001 Here we find that upon ATP binding, mimicked by the non-hydrolysable analog AMP-PNP (5"-adenylyl-imido-diphosphate), to both CCT-alpha-actin and CCT- beta-tubulin complexes, the chaperonin component undergoes concerted movements of the apical domains, resulting in the cavity being closed off by the helical protrusions of the eight apical domains. Adenosine Triphosphate 23-26 t-complex 1 Homo sapiens 125-134 11483510-3 2001 Here we find that upon ATP binding, mimicked by the non-hydrolysable analog AMP-PNP (5"-adenylyl-imido-diphosphate), to both CCT-alpha-actin and CCT- beta-tubulin complexes, the chaperonin component undergoes concerted movements of the apical domains, resulting in the cavity being closed off by the helical protrusions of the eight apical domains. Adenylyl Imidodiphosphate 76-83 t-complex 1 Homo sapiens 125-134 11483510-3 2001 Here we find that upon ATP binding, mimicked by the non-hydrolysable analog AMP-PNP (5"-adenylyl-imido-diphosphate), to both CCT-alpha-actin and CCT- beta-tubulin complexes, the chaperonin component undergoes concerted movements of the apical domains, resulting in the cavity being closed off by the helical protrusions of the eight apical domains. 5"-adenylyl-imido-diphosphate 85-114 t-complex 1 Homo sapiens 125-134 8573069-6 1996 The predicted HsCCT gamma amino acid sequence shares a high degree of sequence similarity with gamma-subunits from the mouse Mus musculus (98% similarity), the yeast Saccharomyces cerevisiae (75% similarity) and the protozoan Tetrahymena pyriformis (76% similarity) as well as with other members of the TF55/TCP-1 family, such as human TCP-1/CCT alpha (55% similarity) and TCP-20/CCT zeta (54% similarity). gamma amino acid 20-36 t-complex 1 Homo sapiens 336-341 8573069-6 1996 The predicted HsCCT gamma amino acid sequence shares a high degree of sequence similarity with gamma-subunits from the mouse Mus musculus (98% similarity), the yeast Saccharomyces cerevisiae (75% similarity) and the protozoan Tetrahymena pyriformis (76% similarity) as well as with other members of the TF55/TCP-1 family, such as human TCP-1/CCT alpha (55% similarity) and TCP-20/CCT zeta (54% similarity). gamma amino acid 20-36 t-complex 1 Homo sapiens 342-351 33500737-6 2021 An adamantane (ADA)-modified TCP1 peptide-targeting ligand (TCP1) was used as the guest molecule. Adamantane 3-13 t-complex 1 Homo sapiens 29-33 34137161-10 2022 Three of the four types demonstrated bioactive properties (TCP1, TCP2 and TCPA2), that is, precipitation of crystalline hydroxyapatite as was confirmed by X-ray diffraction. Durapatite 120-134 t-complex 1 Homo sapiens 59-63 34845659-3 2021 PROCEDURES: Cell uptake of cyanine 7 (Cy7)-labeled TCP-1 probes (Cy7-PEG4-TCP-1 and Cy7-TCP-1) was investigated in three CRC cell lines (human, HCT116 and HT29; mouse, CT26). cyanine 7 27-36 t-complex 1 Homo sapiens 51-56 34845659-3 2021 PROCEDURES: Cell uptake of cyanine 7 (Cy7)-labeled TCP-1 probes (Cy7-PEG4-TCP-1 and Cy7-TCP-1) was investigated in three CRC cell lines (human, HCT116 and HT29; mouse, CT26). cyanine dye 7 38-41 t-complex 1 Homo sapiens 51-56 34750375-9 2021 Pharmacological inhibition of AKT/mTOR signal particularly activated autophagy and resensitized TCP1-overexpressing HL60 cells to adriamycin. Doxorubicin 130-140 t-complex 1 Homo sapiens 96-100 34158536-5 2021 We find all subunits CCT1-8 are N-terminally processed by combinations of methionine excision and acetylation observed in native human TRiC. Methionine 74-84 t-complex 1 Homo sapiens 21-27 7890169-4 1995 This gene is different from Tcp-1 and the six Tcp-1-related genes reported previously, Tcp-1 (Ccta), Cctb, Cctg, Cctd, Ccte, Cctz and Ccth, which encode subunits of CCT. ccta 94-98 t-complex 1 Homo sapiens 46-51 7890169-4 1995 This gene is different from Tcp-1 and the six Tcp-1-related genes reported previously, Tcp-1 (Ccta), Cctb, Cctg, Cctd, Ccte, Cctz and Ccth, which encode subunits of CCT. ccta 94-98 t-complex 1 Homo sapiens 46-51 7553912-2 1995 Both additional tubulins probably bind GTP but lack GTPase activity, while their synthesis requires the TCP1 chaperonine but is not autoregulated. chaperonine 109-120 t-complex 1 Homo sapiens 104-108 7876352-0 1994 TRiC-P5, a novel TCP1-related protein, is localized in the cytoplasm and in the nuclear matrix. tric-p5 0-7 t-complex 1 Homo sapiens 17-21 7919008-6 1994 Side views from different forms of TCP-1 reveals that upon Mg-ATP binding, the cytoplasmic chaperonin undergoes a structural rearrangement that is confirmed using a new classification method. Adenosine Triphosphate 59-65 t-complex 1 Homo sapiens 35-40 34750375-5 2021 TCP1 showed higher expression in the adriamycin-resistant leukemia cell line HL60/A and K562/A, comparing to their respective parent cells HL60 and K562 cells. Doxorubicin 37-47 t-complex 1 Homo sapiens 0-4 34750375-7 2021 Mechanistic investigations revealed that TCP1 inhibited autophagy and adriamycin-induced cell apoptosis, and TCP1-mediated autophagy inhibition conferred resistance to adriamycin-induced cell apoptosis. Doxorubicin 70-80 t-complex 1 Homo sapiens 41-45 34750375-7 2021 Mechanistic investigations revealed that TCP1 inhibited autophagy and adriamycin-induced cell apoptosis, and TCP1-mediated autophagy inhibition conferred resistance to adriamycin-induced cell apoptosis. Doxorubicin 168-178 t-complex 1 Homo sapiens 109-113 34226146-1 2021 T cell asymmetry upon specific cell-cell interactions during mammalian immunological synapse (IS) contacts requires mammalian target of rapamycin complex (mTORC) activation and chaperones, such as the eukaryotic chaperonin containing TCP1 (CCT) for protein synthesis and folding. Sirolimus 136-145 t-complex 1 Homo sapiens 234-238 33500737-11 2021 Notably, targeted therapy via the co-delivery of 5-FU and miR-34a(m) by TCP1-CD-QD nanocarriers significantly inhibited the growth of PDX tumors. Fluorouracil 49-53 t-complex 1 Homo sapiens 72-76 33500737-6 2021 An adamantane (ADA)-modified TCP1 peptide-targeting ligand (TCP1) was used as the guest molecule. Adamantane 3-13 t-complex 1 Homo sapiens 60-64 33500737-6 2021 An adamantane (ADA)-modified TCP1 peptide-targeting ligand (TCP1) was used as the guest molecule. Adamantane 15-18 t-complex 1 Homo sapiens 29-33 33500737-6 2021 An adamantane (ADA)-modified TCP1 peptide-targeting ligand (TCP1) was used as the guest molecule. Adamantane 15-18 t-complex 1 Homo sapiens 60-64 33500737-7 2021 5-FU and miR-34a(m) were loaded into TCP1-CD-QD nanocarriers, which were used to treat CRC in vitro and in vivo. Fluorouracil 0-4 t-complex 1 Homo sapiens 37-41 33500737-9 2021 Results: 5-FU and miR-34a(m) can be efficiently encapsulated into TCP1-CD-QD nanocarriers and delivered into CRC cells, which led to the inhibition of the proliferation and migration of CRC cells in vitro and suppression of tumor growth in a CRC cell-derived tumor xenograft model. Fluorouracil 9-13 t-complex 1 Homo sapiens 66-70 32505823-5 2020 (b) Matrine inhibited the expression of miR-182-5p and induced the apoptosis of TCP-1 and BCPAP cells in a dose-dependent manner. matrine 4-11 t-complex 1 Homo sapiens 80-85 32780796-9 2020 This suggests that CCTalpha not only displays structural but also functional adaptations to deep water conditions. Water 97-102 t-complex 1 Homo sapiens 19-27 32505823-6 2020 (c) Matrine increased caspase3 expression levels and reduced Bcl-2 expression levels in both TCP-1 and BCPAP cells. matrine 4-11 t-complex 1 Homo sapiens 93-98 32505823-10 2020 In conclusion, these results demonstrate that matrine exerts antitumor effects possibly by inducing the apoptosis of TCP-1 and BCPAP cells, decreasing the level of Bcl-2, activating caspase3 and suppressing PTC tumor growth by downregulating the expression of miR-182-5p. matrine 46-53 t-complex 1 Homo sapiens 117-122 27574992-2 2016 The objective of this study was to characterize c[CTPSPFSHC]OH (TCP-1), a small peptide derived from phage display selection, for targeting human CRC xenografts using technetium-99m ((99m)Tc)-labeled TCP-1 and fluorescent cyanine-7 (Cy7)-labeled form of the peptide (Cy7-TCP-1). c[ctpspfshc]oh 48-62 t-complex 1 Homo sapiens 64-69 30953761-8 2019 The silencing of CCTalpha, the key enzyme in PC synthesis, prevents SFA-mediated NLRP3 activation, demonstrating the essential role of the de novo PC synthesis. Phosphatidylcholines 45-47 t-complex 1 Homo sapiens 17-25 28674660-2 2017 We aimed to study the association between maternal alcohol consumption during pregnancy and the child"s cognitive performance using the Kaufman Assessment Battery for Children, 2nd edition (KABC-II) and the Children"s Category Test Level 1 (CCT-1) in rural Burkina Faso. Alcohols 51-58 t-complex 1 Homo sapiens 207-239 28674660-2 2017 We aimed to study the association between maternal alcohol consumption during pregnancy and the child"s cognitive performance using the Kaufman Assessment Battery for Children, 2nd edition (KABC-II) and the Children"s Category Test Level 1 (CCT-1) in rural Burkina Faso. Alcohols 51-58 t-complex 1 Homo sapiens 241-246 28674660-7 2017 Children whose mothers reported alcohol consumption during pregnancy performed significantly poorly for memory and spatial abilities tests from small effect size difference for "Atlantis" (0.27) and "Triangle" (0.29) to moderate effect size difference for "Number recall" (0.72) compared to children whose mothers did not consume alcohol during pregnancy; the exposed children scored significantly higher errors with a small effect size (0.37) at problem solving (CCT-1) test compared to unexposed children. Alcohols 32-39 t-complex 1 Homo sapiens 464-469 27574992-2 2016 The objective of this study was to characterize c[CTPSPFSHC]OH (TCP-1), a small peptide derived from phage display selection, for targeting human CRC xenografts using technetium-99m ((99m)Tc)-labeled TCP-1 and fluorescent cyanine-7 (Cy7)-labeled form of the peptide (Cy7-TCP-1). cyanine-7 222-231 t-complex 1 Homo sapiens 64-69 27574992-2 2016 The objective of this study was to characterize c[CTPSPFSHC]OH (TCP-1), a small peptide derived from phage display selection, for targeting human CRC xenografts using technetium-99m ((99m)Tc)-labeled TCP-1 and fluorescent cyanine-7 (Cy7)-labeled form of the peptide (Cy7-TCP-1). cyanine dye 7 233-236 t-complex 1 Homo sapiens 64-69 27574992-2 2016 The objective of this study was to characterize c[CTPSPFSHC]OH (TCP-1), a small peptide derived from phage display selection, for targeting human CRC xenografts using technetium-99m ((99m)Tc)-labeled TCP-1 and fluorescent cyanine-7 (Cy7)-labeled form of the peptide (Cy7-TCP-1). c[ctpspfshc]oh 48-62 t-complex 1 Homo sapiens 200-205 27574992-3 2016 (99m)Tc-TCP-1 was generated by modifying TCP-1 with succinimidyl-6-hydrazino-nicotinamide (S-HYNIC) followed by radiolabeling. SCHEMBL15634880 52-89 t-complex 1 Homo sapiens 8-13 27574992-2 2016 The objective of this study was to characterize c[CTPSPFSHC]OH (TCP-1), a small peptide derived from phage display selection, for targeting human CRC xenografts using technetium-99m ((99m)Tc)-labeled TCP-1 and fluorescent cyanine-7 (Cy7)-labeled form of the peptide (Cy7-TCP-1). c[ctpspfshc]oh 48-62 t-complex 1 Homo sapiens 200-205 27574992-3 2016 (99m)Tc-TCP-1 was generated by modifying TCP-1 with succinimidyl-6-hydrazino-nicotinamide (S-HYNIC) followed by radiolabeling. SCHEMBL15634880 52-89 t-complex 1 Homo sapiens 41-46 27574992-2 2016 The objective of this study was to characterize c[CTPSPFSHC]OH (TCP-1), a small peptide derived from phage display selection, for targeting human CRC xenografts using technetium-99m ((99m)Tc)-labeled TCP-1 and fluorescent cyanine-7 (Cy7)-labeled form of the peptide (Cy7-TCP-1). Technetium-99 167-180 t-complex 1 Homo sapiens 64-69 27574992-9 2016 In vitro(99m)Tc-HYNIC-TCP-1 binding assays on HCT 116 cells indicated a mean Kd of 3.04+-0.52nM. Technetium 13-15 t-complex 1 Homo sapiens 22-27 27574992-2 2016 The objective of this study was to characterize c[CTPSPFSHC]OH (TCP-1), a small peptide derived from phage display selection, for targeting human CRC xenografts using technetium-99m ((99m)Tc)-labeled TCP-1 and fluorescent cyanine-7 (Cy7)-labeled form of the peptide (Cy7-TCP-1). Technetium 188-190 t-complex 1 Homo sapiens 64-69 23995979-0 2014 Isolation and characterization of a novel Dehalobacter species strain TCP1 that reductively dechlorinates 2,4,6-trichlorophenol. 2,4,6-trichlorophenol 106-127 t-complex 1 Homo sapiens 70-74 24861627-8 2014 Together, our results indicate that the TCP1 complex binds oligonucleotides with TCP1-beta subunit being a nuclear PS-body component and suggest that the TCP1 complex may facilitate PS-ASO uptake and/or release from the endocytosis pathway. Oligonucleotides 59-75 t-complex 1 Homo sapiens 81-85 24861627-8 2014 Together, our results indicate that the TCP1 complex binds oligonucleotides with TCP1-beta subunit being a nuclear PS-body component and suggest that the TCP1 complex may facilitate PS-ASO uptake and/or release from the endocytosis pathway. ps-aso 182-188 t-complex 1 Homo sapiens 40-44 24861627-8 2014 Together, our results indicate that the TCP1 complex binds oligonucleotides with TCP1-beta subunit being a nuclear PS-body component and suggest that the TCP1 complex may facilitate PS-ASO uptake and/or release from the endocytosis pathway. ps-aso 182-188 t-complex 1 Homo sapiens 81-85 24861627-0 2014 TCP1 complex proteins interact with phosphorothioate oligonucleotides and can co-localize in oligonucleotide-induced nuclear bodies in mammalian cells. Phosphorothioate Oligonucleotides 36-69 t-complex 1 Homo sapiens 0-4 24861627-0 2014 TCP1 complex proteins interact with phosphorothioate oligonucleotides and can co-localize in oligonucleotide-induced nuclear bodies in mammalian cells. Oligonucleotides 53-68 t-complex 1 Homo sapiens 0-4 24861627-4 2014 Here we report that in cells transfected with PS-ASOs, the chaperonin T-complex 1 (TCP1) proteins interact with PS-ASOs and enhance antisense activity. ps-asos 46-53 t-complex 1 Homo sapiens 70-81 24861627-4 2014 Here we report that in cells transfected with PS-ASOs, the chaperonin T-complex 1 (TCP1) proteins interact with PS-ASOs and enhance antisense activity. ps-asos 46-53 t-complex 1 Homo sapiens 83-87 24861627-4 2014 Here we report that in cells transfected with PS-ASOs, the chaperonin T-complex 1 (TCP1) proteins interact with PS-ASOs and enhance antisense activity. ps-asos 112-119 t-complex 1 Homo sapiens 70-81 24861627-4 2014 Here we report that in cells transfected with PS-ASOs, the chaperonin T-complex 1 (TCP1) proteins interact with PS-ASOs and enhance antisense activity. ps-asos 112-119 t-complex 1 Homo sapiens 83-87 24861627-7 2014 Upon free uptake, PS-ASOs co-localize with TCP1 proteins in cytoplasmic foci related to endosomes/lysosomes. ps-asos 18-25 t-complex 1 Homo sapiens 43-47 24861627-8 2014 Together, our results indicate that the TCP1 complex binds oligonucleotides with TCP1-beta subunit being a nuclear PS-body component and suggest that the TCP1 complex may facilitate PS-ASO uptake and/or release from the endocytosis pathway. Oligonucleotides 59-75 t-complex 1 Homo sapiens 40-44 23995979-4 2014 The growth yields of strain TCP1 on TCE and 2,4,6-TCP were 4.14 x 10(13) and 5.77 x 10(13) cells mol(-1) of Cl(-) released, respectively. Trichloroethylene 36-39 t-complex 1 Homo sapiens 28-32 23995979-4 2014 The growth yields of strain TCP1 on TCE and 2,4,6-TCP were 4.14 x 10(13) and 5.77 x 10(13) cells mol(-1) of Cl(-) released, respectively. 2,4,6-trichlorophenol 44-53 t-complex 1 Homo sapiens 28-32 23995979-9 2014 Strain TCP1 can serve as a promising candidate for the bioremediation of 2,4,6-TCP contaminated sites, and its discovery expands our understanding of metabolic capabilities of Dehalobacter species. 2,4,6-trichlorophenol 73-82 t-complex 1 Homo sapiens 7-11 23995979-2 2014 In this study, a Dehalobacter species strain TCP1 was isolated from a digester sludge sample, which is able to dechlorinate 2,4,6-trichlorophenol (2,4,6-TCP) to 4-monochlorophenol (4-MCP) with H2 as the sole electron donor and acetate as the carbon source. 2,4,6-trichlorophenol 124-145 t-complex 1 Homo sapiens 45-49 23995979-2 2014 In this study, a Dehalobacter species strain TCP1 was isolated from a digester sludge sample, which is able to dechlorinate 2,4,6-trichlorophenol (2,4,6-TCP) to 4-monochlorophenol (4-MCP) with H2 as the sole electron donor and acetate as the carbon source. 2,4,6-trichlorophenol 147-156 t-complex 1 Homo sapiens 45-49 23995979-2 2014 In this study, a Dehalobacter species strain TCP1 was isolated from a digester sludge sample, which is able to dechlorinate 2,4,6-trichlorophenol (2,4,6-TCP) to 4-monochlorophenol (4-MCP) with H2 as the sole electron donor and acetate as the carbon source. 4-chlorophenol 161-179 t-complex 1 Homo sapiens 45-49 23995979-2 2014 In this study, a Dehalobacter species strain TCP1 was isolated from a digester sludge sample, which is able to dechlorinate 2,4,6-trichlorophenol (2,4,6-TCP) to 4-monochlorophenol (4-MCP) with H2 as the sole electron donor and acetate as the carbon source. Hydrogen 193-195 t-complex 1 Homo sapiens 45-49 23995979-2 2014 In this study, a Dehalobacter species strain TCP1 was isolated from a digester sludge sample, which is able to dechlorinate 2,4,6-trichlorophenol (2,4,6-TCP) to 4-monochlorophenol (4-MCP) with H2 as the sole electron donor and acetate as the carbon source. Acetates 227-234 t-complex 1 Homo sapiens 45-49 23995979-2 2014 In this study, a Dehalobacter species strain TCP1 was isolated from a digester sludge sample, which is able to dechlorinate 2,4,6-trichlorophenol (2,4,6-TCP) to 4-monochlorophenol (4-MCP) with H2 as the sole electron donor and acetate as the carbon source. Carbon 242-248 t-complex 1 Homo sapiens 45-49 23995979-3 2014 Strain TCP1 also distinguishes itself from other Dehalobacter species with its capability to dechlorinate tetrachloroethene or trichloroethene (TCE) to both cis- and trans-dichloroethenes in a ratio of 5.6 (+-0.2):1. Tetrachloroethylene 106-123 t-complex 1 Homo sapiens 7-11 23995979-3 2014 Strain TCP1 also distinguishes itself from other Dehalobacter species with its capability to dechlorinate tetrachloroethene or trichloroethene (TCE) to both cis- and trans-dichloroethenes in a ratio of 5.6 (+-0.2):1. Trichloroethylene 127-142 t-complex 1 Homo sapiens 7-11 23995979-3 2014 Strain TCP1 also distinguishes itself from other Dehalobacter species with its capability to dechlorinate tetrachloroethene or trichloroethene (TCE) to both cis- and trans-dichloroethenes in a ratio of 5.6 (+-0.2):1. Trichloroethylene 144-147 t-complex 1 Homo sapiens 7-11 23995979-3 2014 Strain TCP1 also distinguishes itself from other Dehalobacter species with its capability to dechlorinate tetrachloroethene or trichloroethene (TCE) to both cis- and trans-dichloroethenes in a ratio of 5.6 (+-0.2):1. cis- and trans-dichloroethenes 157-187 t-complex 1 Homo sapiens 7-11 21924303-7 2012 As leaf senescence is controlled by miR319 regulation of the transcription factor TCP1, we assessed the accumulation of both RNAs in transgenic NSs-expressing and GBNV-infected tomato plants. mir319 36-42 t-complex 1 Homo sapiens 82-86 22133715-6 2012 The CCT1 subunit was engineered to carry a hexa-histidine tag or FLAG tag in the internal loop region. Histidine 48-57 t-complex 1 Homo sapiens 4-8 22621903-2 2012 CCTalpha becomes activated with translocation from the cytoplasm to the nuclear membrane, resulting in increased membrane phospholipids. Phospholipids 122-135 t-complex 1 Homo sapiens 0-8 22621903-4 2012 Here CaMK1 phosphorylates residues within this C-terminus that signals association of CCTalpha with 14-3-3 zeta to initiate calcium-induced nuclear entry. Calcium 124-131 t-complex 1 Homo sapiens 86-94 22230298-3 2012 Numerous differentially expressed proteins were identified with MALDI-TOF/TOF-MS. Cyclophilin A, Catalase, Nucleophosmin and PCNA were decreased exclusively by azacitidine, TCP1 and hnRNP A2/B1 by both drugs; alpha-Enolase and Peroxiredoxin-1 by decitabine. Decitabine 246-256 t-complex 1 Homo sapiens 173-177 20007511-0 2010 14-3-3zeta escorts CCTalpha for calcium-activated nuclear import in lung epithelia. Calcium 32-39 t-complex 1 Homo sapiens 19-27 20007511-2 2010 Phosphatidylcholine, an indispensible membrane component, requires the enzyme CCTalpha for its biosynthesis. Phosphatidylcholines 0-19 t-complex 1 Homo sapiens 78-86 20007511-7 2010 Helix G within the 14-3-3zeta binding groove interacts with a putative molecular signature within the CCTalpha carboxyl-terminal phosphoserine motif (residues 328-343). Phosphoserine 129-142 t-complex 1 Homo sapiens 102-110 20007511-9 2010 Thus, 14-3-3zeta controls CCTalpha nuclear import in response to calcium signals, thereby regulating mammalian phospholipid synthesis. Calcium 65-72 t-complex 1 Homo sapiens 26-34 20007511-9 2010 Thus, 14-3-3zeta controls CCTalpha nuclear import in response to calcium signals, thereby regulating mammalian phospholipid synthesis. Phospholipids 111-123 t-complex 1 Homo sapiens 26-34 20007511-11 2010 B., Schuster, C. C., Houtman, J. C. D., Mallampalli, R. K. 14-3-3zeta escorts CCTalpha for calcium-activated nuclear import in lung epithelia. Calcium 91-98 t-complex 1 Homo sapiens 78-86