PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 17466351-9 2007 Both 3,6-BPQ and 1,6-BPQ induced oxidative stress-associated genes (HMOX1, GCLC, GCLM, and SLC7A11), phase 2 enzyme genes (NQO1, NQO2, ALDH3A1), PAH metabolizing genes (CYP1B1, EPHX1, AKR1C1), and certain EGF receptor-associated genes (EGFR, IER3, ING1, SQSTM1 and TRIM16). benzo(a)pyrene-3,6-quinone 5-12 epoxide hydrolase 1 Homo sapiens 177-182 19547151-1 2007 We report two emission bands corresponding to the spectral line narrowing (SLN) of the conjugated polymer [2-methoxy-5-(2"-ethylhexyloxy)-1, 4-phenylenevinylene] (MEH-PPV) in films. Polymers 98-105 epoxide hydrolase 1 Homo sapiens 163-166 19547151-1 2007 We report two emission bands corresponding to the spectral line narrowing (SLN) of the conjugated polymer [2-methoxy-5-(2"-ethylhexyloxy)-1, 4-phenylenevinylene] (MEH-PPV) in films. 2-methoxy-5-(2"-ethylhexyloxy)-1, 4-phenylenevinylene] 107-161 epoxide hydrolase 1 Homo sapiens 163-166 17466351-9 2007 Both 3,6-BPQ and 1,6-BPQ induced oxidative stress-associated genes (HMOX1, GCLC, GCLM, and SLC7A11), phase 2 enzyme genes (NQO1, NQO2, ALDH3A1), PAH metabolizing genes (CYP1B1, EPHX1, AKR1C1), and certain EGF receptor-associated genes (EGFR, IER3, ING1, SQSTM1 and TRIM16). 1,6-bpq 17-24 epoxide hydrolase 1 Homo sapiens 177-182 17082176-1 2007 NADP(H):quinone oxidoreductase 1 (NQO1) and microsomal epoxide hydrolase (EPHX1, also mEH) are attractive candidate enzymes for association with colorectal neoplasia because they metabolize a number of compounds including polycyclic aromatic hydrocarbons (PAHs) that have been linked with colorectal carcinogenesis. Polycyclic Aromatic Hydrocarbons 222-254 epoxide hydrolase 1 Homo sapiens 44-72 17492880-1 2007 Photoexcitation kinetics and interfacial electronic structures of poly[2-methoxy-5(2-ethylhexyloxy)-p-phenylene vinylene] (MEH-PPV) film on gold have been investigated using two-photon photoemission spectroscopy (2PPE). poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 66-121 epoxide hydrolase 1 Homo sapiens 123-126 17492880-6 2007 The work function of MEH-PPV/Au is measured to be 3.9 eV, 1.2 eV downshift from the clean gold, attributable to interface dipole effects. Gold 29-31 epoxide hydrolase 1 Homo sapiens 21-24 17082176-1 2007 NADP(H):quinone oxidoreductase 1 (NQO1) and microsomal epoxide hydrolase (EPHX1, also mEH) are attractive candidate enzymes for association with colorectal neoplasia because they metabolize a number of compounds including polycyclic aromatic hydrocarbons (PAHs) that have been linked with colorectal carcinogenesis. Polycyclic Aromatic Hydrocarbons 222-254 epoxide hydrolase 1 Homo sapiens 74-79 17082176-1 2007 NADP(H):quinone oxidoreductase 1 (NQO1) and microsomal epoxide hydrolase (EPHX1, also mEH) are attractive candidate enzymes for association with colorectal neoplasia because they metabolize a number of compounds including polycyclic aromatic hydrocarbons (PAHs) that have been linked with colorectal carcinogenesis. Polycyclic Aromatic Hydrocarbons 256-260 epoxide hydrolase 1 Homo sapiens 44-72 17082176-1 2007 NADP(H):quinone oxidoreductase 1 (NQO1) and microsomal epoxide hydrolase (EPHX1, also mEH) are attractive candidate enzymes for association with colorectal neoplasia because they metabolize a number of compounds including polycyclic aromatic hydrocarbons (PAHs) that have been linked with colorectal carcinogenesis. Polycyclic Aromatic Hydrocarbons 256-260 epoxide hydrolase 1 Homo sapiens 74-79 17291185-1 2007 A combination of single-molecule spectroscopy and analysis with simulations is used to provide detailed information about the structural and dynamic properties of a fluorescent polymer MEH-PPV (poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene]) immersed in a nematic and smectic solvent. poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene 194-251 epoxide hydrolase 1 Homo sapiens 185-188 17279712-0 2007 Thin film fabrication of PMMA/MEH-PPV immiscible blends by corona discharge coating and its application to polymer light emitting diodes. Polymers 107-114 epoxide hydrolase 1 Homo sapiens 30-33 17279712-1 2007 We introduce a new and facile process, corona discharge coating (CDC), to fabricate thin polymer films of the immiscible poly[2-methoxy-5-(2"-ethylhexyloxy)-p-phenylenevinylene] (MEH-PPV) and poly(methyl methacrylate) (PMMA) blends. Polymers 89-96 epoxide hydrolase 1 Homo sapiens 179-182 17279712-1 2007 We introduce a new and facile process, corona discharge coating (CDC), to fabricate thin polymer films of the immiscible poly[2-methoxy-5-(2"-ethylhexyloxy)-p-phenylenevinylene] (MEH-PPV) and poly(methyl methacrylate) (PMMA) blends. poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 121-177 epoxide hydrolase 1 Homo sapiens 179-182 17078101-4 2006 Analysis of the effect of pairs of genes showed that for a fixed GSTT1 genotype, the SCE level increased with an increasing number of Tyr alleles in EPHX codon 113. Tyrosine 134-137 epoxide hydrolase 1 Homo sapiens 149-153 17181237-4 2006 The difference in average modulation depth can be explained in terms of lower field-induced exciton dissociation rates in the MEH-PPV/polystyrene system compared to MEH-PPV/PMMA because of a lack of suitable acceptor sites. Polystyrenes 134-145 epoxide hydrolase 1 Homo sapiens 126-129 17136272-3 2006 We present a series of photoluminescence spectra of thin films of the conjugated polymer poly(2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene-vinylene) (MEH-PPV) with a wide range of varying thickness. poly(2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene-vinylene) 89-149 epoxide hydrolase 1 Homo sapiens 151-154 17375979-13 2007 Likewise, the active metabolite of carbamazepine, carbamazepine-10,11-epoxide, is transformed by the microsomal epoxide hydrolase, an enzyme that is also highly polymorphic, but the pharmacokinetic and clinical consequences still need to be evaluated. Carbamazepine 35-48 epoxide hydrolase 1 Homo sapiens 101-129 17375979-13 2007 Likewise, the active metabolite of carbamazepine, carbamazepine-10,11-epoxide, is transformed by the microsomal epoxide hydrolase, an enzyme that is also highly polymorphic, but the pharmacokinetic and clinical consequences still need to be evaluated. carbamazepine epoxide 50-77 epoxide hydrolase 1 Homo sapiens 101-129 17078101-5 2006 We found that among GSTT1(+) individuals the DEB-induced SCE level was significantly lower when the EPHX 139 codon was His/Arg rather than His/His. Histidine 119-122 epoxide hydrolase 1 Homo sapiens 100-104 17078101-5 2006 We found that among GSTT1(+) individuals the DEB-induced SCE level was significantly lower when the EPHX 139 codon was His/Arg rather than His/His. Arginine 123-126 epoxide hydrolase 1 Homo sapiens 100-104 17361701-0 2006 [Investigation on the photoconductive properties of MEH-PPV/CdSe nanocomposite devices]. cdse 60-64 epoxide hydrolase 1 Homo sapiens 52-55 16872732-5 2006 Both soluble and microsomal epoxide hydrolase inhibitors dramatically enhanced styrene toxicity. Styrene 79-86 epoxide hydrolase 1 Homo sapiens 17-45 17159790-7 2006 CONCLUSIONS: Our results suggest that GSTP1*105Val allele and low EPHX1 activity genotype may be protective for people occupationally exposed to asbestos. Asbestos 145-153 epoxide hydrolase 1 Homo sapiens 66-71 16963132-6 2006 Like trout CYP1A1, cDNA-expressed zCYP1A was found to oxidize BaP to phenols, quinones and diols (BaP-7,8-diol and BaP-9,10-diol) in the presence of exogenous human microsomal epoxide hydrolase (hEH). Benzo(a)pyrene 62-65 epoxide hydrolase 1 Homo sapiens 165-193 17031969-2 2006 In low ionic strength acetonitrile solutions, diffusion of a positively charged species (Fe(bpy)(3)(2+)) is electrostatically blocked with approximately 100% efficiency by UV light-induced conversion of the neutral surface-bound spiropyran to its protonated merocyanine form (MEH+). acetonitrile 22-34 epoxide hydrolase 1 Homo sapiens 276-279 21727606-3 2006 The hybrid solar cells based on the obtained spherical CdSe NCs as an acceptor and Poly(2-methoxy-5-(2"-ethylhexoxy)-p-phenylenevinylene) (MEH-PPV) as a donor show an energy conversion efficiency (ECE) as high as 0.85%, three times higher than that reported before for spherical CdSe NCs/conjugated polymer hybrid solar cells. poly(2-methoxy-5-(2"-ethylhexoxy)-p-phenylenevinylene) 83-137 epoxide hydrolase 1 Homo sapiens 139-142 16963132-6 2006 Like trout CYP1A1, cDNA-expressed zCYP1A was found to oxidize BaP to phenols, quinones and diols (BaP-7,8-diol and BaP-9,10-diol) in the presence of exogenous human microsomal epoxide hydrolase (hEH). diols 91-96 epoxide hydrolase 1 Homo sapiens 165-193 16509700-9 2006 The bulky PPV copolymers showed that both the luminescence intensity (in film) and quantum yields (in solution) increased with an increase in the extent of BTCD incorporation in the MEH-PPV and attained a maximum for 50% BTCD. copolymers 14-24 epoxide hydrolase 1 Homo sapiens 182-185 21727535-2 2006 Herein, the nanocrystals acted as electron acceptors, and poly(2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene) (MEH-PPV) was used as an electron donor. poly(2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene) 58-118 epoxide hydrolase 1 Homo sapiens 120-123 16961213-2 2006 In the present article, we get SSCL under sinusoidal alternating-current voltage with a structure of ITO/SiO2/MEH-PPV/SiO2/Al. sscl 31-35 epoxide hydrolase 1 Homo sapiens 110-113 16961213-2 2006 In the present article, we get SSCL under sinusoidal alternating-current voltage with a structure of ITO/SiO2/MEH-PPV/SiO2/Al. Silicon Dioxide 118-122 epoxide hydrolase 1 Homo sapiens 110-113 16961213-2 2006 In the present article, we get SSCL under sinusoidal alternating-current voltage with a structure of ITO/SiO2/MEH-PPV/SiO2/Al. Aluminum 123-125 epoxide hydrolase 1 Homo sapiens 110-113 16610868-1 2006 Electrofluorescence (Stark) spectroscopy has been used to measure the trace of the change in polarizability (trDeltaalpha) and the absolute value of the change in dipole moment ( Deltamu ) of the electroluminescent polymer poly[2-methoxy,5-(2"-ethyl-hexoxy)-1,4-phenylene vinylene] (MEH-PPV) and several model oligomers in solvent glass matrixes. Polymers 215-222 epoxide hydrolase 1 Homo sapiens 283-286 16630050-0 2006 Expression of microsomal epoxide hydrolase is elevated in Alzheimer"s hippocampus and induced by exogenous beta-amyloid and trimethyl-tin. beta-amyloid 107-119 epoxide hydrolase 1 Homo sapiens 14-42 16630050-0 2006 Expression of microsomal epoxide hydrolase is elevated in Alzheimer"s hippocampus and induced by exogenous beta-amyloid and trimethyl-tin. trimethyltin 124-137 epoxide hydrolase 1 Homo sapiens 14-42 16836118-2 2006 The photoluminescence efficiency of double layer sample PEDOT/MEH-PPV was enhanced by doping one-dimensional nanomaterials (TiO2 nanotube and ZnO nanorod) into PEDOT layer. titanium dioxide 124-128 epoxide hydrolase 1 Homo sapiens 62-65 16836118-2 2006 The photoluminescence efficiency of double layer sample PEDOT/MEH-PPV was enhanced by doping one-dimensional nanomaterials (TiO2 nanotube and ZnO nanorod) into PEDOT layer. Zinc Oxide 142-145 epoxide hydrolase 1 Homo sapiens 62-65 16484233-4 2006 BaP exposure also increased both CYP1A1/1B1 and microsomal epoxide hydrolase (mEH) enzyme activities with a maximum 10-fold increase at 48 h. BaP induced CYP1A1 protein and mRNA levels maximally after 48 h. In contrast, although CYP1B1 mRNA was rapidly induced, its protein expression showed a very poor response. Benzo(a)pyrene 0-3 epoxide hydrolase 1 Homo sapiens 48-76 16484233-4 2006 BaP exposure also increased both CYP1A1/1B1 and microsomal epoxide hydrolase (mEH) enzyme activities with a maximum 10-fold increase at 48 h. BaP induced CYP1A1 protein and mRNA levels maximally after 48 h. In contrast, although CYP1B1 mRNA was rapidly induced, its protein expression showed a very poor response. Benzo(a)pyrene 142-145 epoxide hydrolase 1 Homo sapiens 48-76 16456143-11 2006 SNPs in EPHX1 were associated with carbon monoxide diffusing capacity (p < or = 0.04). Carbon Monoxide 35-50 epoxide hydrolase 1 Homo sapiens 8-13 16125881-4 2005 The subjects" genetic polymorphisms in the genes that encode the styrene-metabolizing enzymes CYP2E1, CYP2B6, EPHX1, GSTM1, GSTT1 and GSTP1 were determined. Styrene 65-72 epoxide hydrolase 1 Homo sapiens 110-115 16424821-5 2006 The possible influence of genetic polymorphisms of xenobiotic-metabolizing enzymes involved in styrene biotransformation (EPHX1, GSTT1, GSTM1, GSTP1) and NAT2 on the cytogenetic endpoints was investigated. Styrene 95-102 epoxide hydrolase 1 Homo sapiens 122-127 16472005-6 2006 A number of late transition metal complexes were found to successfully catalyze polymerization of MeH2SiSiH2Me toward soluble, linear poly(methylsilane). Metals 28-33 epoxide hydrolase 1 Homo sapiens 98-101 16472005-6 2006 A number of late transition metal complexes were found to successfully catalyze polymerization of MeH2SiSiH2Me toward soluble, linear poly(methylsilane). poly(methylsilane) 134-152 epoxide hydrolase 1 Homo sapiens 98-101 16826896-1 2006 Organic-inorganic single quantum well with organic heterojunction ITO\SiO2 (60 nm)\MEH-PPV(40 nm)\Alq3 (40 nm)\SiO2 (60 nm)\Al has been fabricated. tris-(8-hydroxyquinoline)aluminum 98-102 epoxide hydrolase 1 Homo sapiens 83-86 16125881-9 2005 When the combined influence of the CYP2B6 genotype and the predicted activity of EPHX1 were examined, urinary metabolites in subjects with low enzyme activity were lower than in those with medium or high activity after high styrene exposure (>or=50 ppm). Styrene 224-231 epoxide hydrolase 1 Homo sapiens 81-86 16351200-1 2005 This study reports the fabrication and characterization of nanoscale organic light-emitting diodes (nano-OLEDs) based on poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV). poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] 121-180 epoxide hydrolase 1 Homo sapiens 182-185 16852213-1 2005 Single molecule fluorescence correlation spectroscopy has been used to investigate the photodynamics of isolated single multichromophoric polymer chains of the conjugated polymers MEH-PPV and F8BT on the microsecond to millisecond time scale. Polymers 138-145 epoxide hydrolase 1 Homo sapiens 180-183 16224763-1 2005 Herein, we continue our investigation of the single-molecule spectroscopy of the conjugated polymer poly[2-methoxy,5-(2"-ethylhexyloxy)-p-phenylene-vinylene] (MEH-PPV) at cryogenic temperatures. Polymers 92-99 epoxide hydrolase 1 Homo sapiens 159-162 16224763-1 2005 Herein, we continue our investigation of the single-molecule spectroscopy of the conjugated polymer poly[2-methoxy,5-(2"-ethylhexyloxy)-p-phenylene-vinylene] (MEH-PPV) at cryogenic temperatures. poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 100-157 epoxide hydrolase 1 Homo sapiens 159-162 16224763-2 2005 First, the low temperature microsecond dynamics of single MEH-PPV conjugated polymer molecules are compared to the dynamics at room temperature revealing no detectible temperature dependence. Polymers 77-84 epoxide hydrolase 1 Homo sapiens 58-61 16853293-1 2005 The photophysics of MEH-PPV incorporated into the pores of periodic silica hosts has been investigated in an effort to understand the role played by interchain aggregation and chain morphology in polaron production. Silicon Dioxide 68-74 epoxide hydrolase 1 Homo sapiens 20-23 16853293-2 2005 In this work, guest/host interactions were used to incorporate MEH-PPV into the straight, homogeneous pores of hexagonal surfactant- or polymer-templated mesoporous silicas of varying pore diameters. Silicon Dioxide 165-172 epoxide hydrolase 1 Homo sapiens 63-66 16095381-1 2005 We study electrochemical p- and n-type doping in the well-known light-emitting polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV). Polymers 79-86 epoxide hydrolase 1 Homo sapiens 146-149 16095381-1 2005 We study electrochemical p- and n-type doping in the well-known light-emitting polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV). poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 87-144 epoxide hydrolase 1 Homo sapiens 146-149 15826809-0 2005 Molecular modelling of human microsomal epoxide hydrolase (EH) by homology with a fungal (Aspergillus niger) EH crystal structure of 1.8 A resolution: structure-activity relationships in epoxides inhibiting EH activity. Epoxy Compounds 187-195 epoxide hydrolase 1 Homo sapiens 29-57 16853463-1 2005 The fluorescence of single chains of the conductive polymer poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV) was studied by means of single-molecule spectroscopy at 15 K. MEH-PPV was deposited onto a surface from a toluene solution and covered with a polymer cap layer of poly(vinyl alcohol) spin-coated from an aqueous solution for protection against air. Polymers 52-59 epoxide hydrolase 1 Homo sapiens 121-124 16853463-1 2005 The fluorescence of single chains of the conductive polymer poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV) was studied by means of single-molecule spectroscopy at 15 K. MEH-PPV was deposited onto a surface from a toluene solution and covered with a polymer cap layer of poly(vinyl alcohol) spin-coated from an aqueous solution for protection against air. Polymers 52-59 epoxide hydrolase 1 Homo sapiens 192-195 16853463-1 2005 The fluorescence of single chains of the conductive polymer poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV) was studied by means of single-molecule spectroscopy at 15 K. MEH-PPV was deposited onto a surface from a toluene solution and covered with a polymer cap layer of poly(vinyl alcohol) spin-coated from an aqueous solution for protection against air. poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene 60-118 epoxide hydrolase 1 Homo sapiens 121-124 16853463-1 2005 The fluorescence of single chains of the conductive polymer poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV) was studied by means of single-molecule spectroscopy at 15 K. MEH-PPV was deposited onto a surface from a toluene solution and covered with a polymer cap layer of poly(vinyl alcohol) spin-coated from an aqueous solution for protection against air. poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene 60-118 epoxide hydrolase 1 Homo sapiens 192-195 16853463-1 2005 The fluorescence of single chains of the conductive polymer poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV) was studied by means of single-molecule spectroscopy at 15 K. MEH-PPV was deposited onto a surface from a toluene solution and covered with a polymer cap layer of poly(vinyl alcohol) spin-coated from an aqueous solution for protection against air. Toluene 236-243 epoxide hydrolase 1 Homo sapiens 121-124 16853463-1 2005 The fluorescence of single chains of the conductive polymer poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV) was studied by means of single-molecule spectroscopy at 15 K. MEH-PPV was deposited onto a surface from a toluene solution and covered with a polymer cap layer of poly(vinyl alcohol) spin-coated from an aqueous solution for protection against air. Polymers 272-279 epoxide hydrolase 1 Homo sapiens 121-124 16853463-1 2005 The fluorescence of single chains of the conductive polymer poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV) was studied by means of single-molecule spectroscopy at 15 K. MEH-PPV was deposited onto a surface from a toluene solution and covered with a polymer cap layer of poly(vinyl alcohol) spin-coated from an aqueous solution for protection against air. Polyvinyl Alcohol 293-312 epoxide hydrolase 1 Homo sapiens 121-124 15900282-0 2005 Common genetic variants of microsomal epoxide hydrolase affect warfarin dose requirements beyond the effect of cytochrome P450 2C9. Warfarin 63-71 epoxide hydrolase 1 Homo sapiens 27-55 16852072-3 2005 A decrease in the photoluminescence lifetime of MEH-PPV is also observed in the thin film nanocrystal-polymer composite materials. Polymers 102-109 epoxide hydrolase 1 Homo sapiens 48-51 15884078-0 2005 Single chromophore spectroscopy of MEH-PPV: homing-in on the elementary emissive species in conjugated polymers. Polymers 103-111 epoxide hydrolase 1 Homo sapiens 35-38 15884078-2 2005 We demonstrate this with the example of one of the most commonly studied polymers, poly(2-methoxy-5-(2"-ethylhexoxy)-1,4-phenylenevinylene), MEH-PPV, which is shown to exhibit sharp fluorescence signatures over one hundred times narrower than the ensemble. Polymers 73-81 epoxide hydrolase 1 Homo sapiens 141-144 15884078-2 2005 We demonstrate this with the example of one of the most commonly studied polymers, poly(2-methoxy-5-(2"-ethylhexoxy)-1,4-phenylenevinylene), MEH-PPV, which is shown to exhibit sharp fluorescence signatures over one hundred times narrower than the ensemble. poly(2-methoxy-5-(2"-ethylhexoxy)-1,4-phenylenevinylene) 83-139 epoxide hydrolase 1 Homo sapiens 141-144 15716486-2 2005 In humans, these epoxides are detoxified predominantly by hydrolysis, a reaction mediated by the microsomal epoxide hydrolase (mEH; EPHX1) enzyme. Epoxy Compounds 17-25 epoxide hydrolase 1 Homo sapiens 97-125 15986152-2 2005 The system has been used to examine the effects of shear flow on dilute solutions of two commercially available samples of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) in toluene and xylene. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 123-180 epoxide hydrolase 1 Homo sapiens 182-185 15986152-6 2005 In contrast, MEH-PPV dispersed in a concentrated polystyrene solution showed evidence of shear-induced orientation and rheochromism. Polystyrenes 49-60 epoxide hydrolase 1 Homo sapiens 13-16 15716486-2 2005 In humans, these epoxides are detoxified predominantly by hydrolysis, a reaction mediated by the microsomal epoxide hydrolase (mEH; EPHX1) enzyme. Epoxy Compounds 17-25 epoxide hydrolase 1 Homo sapiens 132-137 15692831-0 2005 Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients. carbamazepine epoxide 69-96 epoxide hydrolase 1 Homo sapiens 24-29 15692831-3 2005 METHODS: SNPs of EPHX1 were analyzed by means of polymerase chain reaction amplification and DNA sequencing using DNA extracted from the blood leukocytes of 96 Japanese epileptic patients, including 58 carbamazepine-administered patients. Carbamazepine 202-215 epoxide hydrolase 1 Homo sapiens 17-22 15692831-1 2005 OBJECTIVE: Microsomal epoxide hydrolase (mEH) is an enzyme that detoxifies reactive epoxides and catalyzes the biotransformation of carbamazepine-10,11-epoxide (CBZ-epoxide) to carbamazepine-10,11-diol (CBZ-diol). reactive epoxides 75-92 epoxide hydrolase 1 Homo sapiens 11-39 15692831-11 2005 CONCLUSION: These results show that some EPHX1 haplotypes are associated with altered CBZ-epoxide metabolism. carbamazepine epoxide 86-97 epoxide hydrolase 1 Homo sapiens 41-46 15692831-1 2005 OBJECTIVE: Microsomal epoxide hydrolase (mEH) is an enzyme that detoxifies reactive epoxides and catalyzes the biotransformation of carbamazepine-10,11-epoxide (CBZ-epoxide) to carbamazepine-10,11-diol (CBZ-diol). carbamazepine epoxide 132-159 epoxide hydrolase 1 Homo sapiens 11-39 15692831-1 2005 OBJECTIVE: Microsomal epoxide hydrolase (mEH) is an enzyme that detoxifies reactive epoxides and catalyzes the biotransformation of carbamazepine-10,11-epoxide (CBZ-epoxide) to carbamazepine-10,11-diol (CBZ-diol). carbamazepine epoxide 161-172 epoxide hydrolase 1 Homo sapiens 11-39 15692831-1 2005 OBJECTIVE: Microsomal epoxide hydrolase (mEH) is an enzyme that detoxifies reactive epoxides and catalyzes the biotransformation of carbamazepine-10,11-epoxide (CBZ-epoxide) to carbamazepine-10,11-diol (CBZ-diol). 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide 177-201 epoxide hydrolase 1 Homo sapiens 11-39 15692831-1 2005 OBJECTIVE: Microsomal epoxide hydrolase (mEH) is an enzyme that detoxifies reactive epoxides and catalyzes the biotransformation of carbamazepine-10,11-epoxide (CBZ-epoxide) to carbamazepine-10,11-diol (CBZ-diol). 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide 203-211 epoxide hydrolase 1 Homo sapiens 11-39 15466980-2 2004 Cytochrome P450, glutathione S-transferase, microsomal epoxide hydrolase, NAD(P)H:quinone oxidoreductase, and N-acetyltransferase are PAH-metabolizing enzymes. Polycyclic Aromatic Hydrocarbons 134-137 epoxide hydrolase 1 Homo sapiens 44-72 15668489-2 2005 Microsomal epoxide hydrolase (EPHX1) metabolizes polycyclic aromatic hydrocarbons, carcinogens found in cigarette smoke. Polycyclic Aromatic Hydrocarbons 49-81 epoxide hydrolase 1 Homo sapiens 0-28 15668489-2 2005 Microsomal epoxide hydrolase (EPHX1) metabolizes polycyclic aromatic hydrocarbons, carcinogens found in cigarette smoke. Polycyclic Aromatic Hydrocarbons 49-81 epoxide hydrolase 1 Homo sapiens 30-35 15668489-3 2005 Nonsynonymous variants of EPHX1 at Tyr(113)His (exon 3) and His(139)Arg (exon 4) are associated, respectively, with low ((113)His) and high ((139)Arg) predicted activity. Histidine 43-46 epoxide hydrolase 1 Homo sapiens 26-31 15668489-3 2005 Nonsynonymous variants of EPHX1 at Tyr(113)His (exon 3) and His(139)Arg (exon 4) are associated, respectively, with low ((113)His) and high ((139)Arg) predicted activity. Arginine 68-71 epoxide hydrolase 1 Homo sapiens 26-31 16201204-0 2005 Polymorphisms of microsomal epoxide hydrolase in French vinyl chloride workers. Vinyl Chloride 56-70 epoxide hydrolase 1 Homo sapiens 17-45 16201204-1 2005 OBJECTIVES: The purpose of this study was to determine if polymorphisms in microsomal epoxide hydrolase, an enzyme involved in the metabolism of reactive intermediates of vinyl chloride (VC), contribute to the variable susceptibility to the mutagenic effects of vinyl chloride among exposed workers. Vinyl Chloride 171-185 epoxide hydrolase 1 Homo sapiens 75-103 16201204-1 2005 OBJECTIVES: The purpose of this study was to determine if polymorphisms in microsomal epoxide hydrolase, an enzyme involved in the metabolism of reactive intermediates of vinyl chloride (VC), contribute to the variable susceptibility to the mutagenic effects of vinyl chloride among exposed workers. Vinyl Chloride 187-189 epoxide hydrolase 1 Homo sapiens 75-103 16201204-1 2005 OBJECTIVES: The purpose of this study was to determine if polymorphisms in microsomal epoxide hydrolase, an enzyme involved in the metabolism of reactive intermediates of vinyl chloride (VC), contribute to the variable susceptibility to the mutagenic effects of vinyl chloride among exposed workers. Vinyl Chloride 262-276 epoxide hydrolase 1 Homo sapiens 75-103 16851127-6 2005 The reported results suggest that such MEH-PPV/TiO(2) heterojunctions may be exploited as potential active layers in future photovoltaic and photoelectrochemical devices. titanium dioxide 47-53 epoxide hydrolase 1 Homo sapiens 39-42 15465926-1 2005 Microsomal epoxide hydrolase (EPHX1) catalyzes hydration reactions that determine the cellular disposition of reactive epoxide derivatives. reactive epoxide 110-126 epoxide hydrolase 1 Homo sapiens 0-28 15465926-1 2005 Microsomal epoxide hydrolase (EPHX1) catalyzes hydration reactions that determine the cellular disposition of reactive epoxide derivatives. reactive epoxide 110-126 epoxide hydrolase 1 Homo sapiens 30-35 15535985-1 2004 Human microsomal epoxide hydrolase (EPHX1) is active in the metabolism of many potentially carcinogenic or otherwise genotoxic epoxides, such as those derived from the oxidation of polyaromatic hydrocarbons. Epoxy Compounds 127-135 epoxide hydrolase 1 Homo sapiens 6-34 15535985-1 2004 Human microsomal epoxide hydrolase (EPHX1) is active in the metabolism of many potentially carcinogenic or otherwise genotoxic epoxides, such as those derived from the oxidation of polyaromatic hydrocarbons. Epoxy Compounds 127-135 epoxide hydrolase 1 Homo sapiens 36-41 15535985-1 2004 Human microsomal epoxide hydrolase (EPHX1) is active in the metabolism of many potentially carcinogenic or otherwise genotoxic epoxides, such as those derived from the oxidation of polyaromatic hydrocarbons. Hydrocarbons 194-206 epoxide hydrolase 1 Homo sapiens 6-34 15535985-1 2004 Human microsomal epoxide hydrolase (EPHX1) is active in the metabolism of many potentially carcinogenic or otherwise genotoxic epoxides, such as those derived from the oxidation of polyaromatic hydrocarbons. Hydrocarbons 194-206 epoxide hydrolase 1 Homo sapiens 36-41 15169428-1 2004 We determine the efficiencies for the formation of excitons and charge carriers following ultrafast photoexcitation of a semiconducting polymer (MEH-PPV). Polymers 136-143 epoxide hydrolase 1 Homo sapiens 145-148 15584438-3 2004 As regards exposure to benzene, also relevant is the influence of epoxydohydrolase (EPHX) and NAD(P)H quinone oxidoreductase (NQO1) on the urinary excretion of t,t-muconic and phenylmercapturic acids. Benzene 23-30 epoxide hydrolase 1 Homo sapiens 84-88 15584438-3 2004 As regards exposure to benzene, also relevant is the influence of epoxydohydrolase (EPHX) and NAD(P)H quinone oxidoreductase (NQO1) on the urinary excretion of t,t-muconic and phenylmercapturic acids. t,t-muconic 160-171 epoxide hydrolase 1 Homo sapiens 84-88 15584438-3 2004 As regards exposure to benzene, also relevant is the influence of epoxydohydrolase (EPHX) and NAD(P)H quinone oxidoreductase (NQO1) on the urinary excretion of t,t-muconic and phenylmercapturic acids. S-phenyl-N-acetylcysteine 176-199 epoxide hydrolase 1 Homo sapiens 84-88 15584438-4 2004 With respect to occupational exposure to styrene, EPHX significantly influences the levels of Chromosome Aberrations (CAs), strongly predictive genotoxic biomarkers of cancer risk. Styrene 41-48 epoxide hydrolase 1 Homo sapiens 50-54 15150264-1 2004 Microsomal epoxide hydrolase (mEH) plays a central role in xenobiotic metabolism as well as mediating the sodium-dependent uptake of bile acids into the liver, where these compounds regulate numerous biological processes such as cholesterol metabolism and hepatocyte signaling pathways. Sodium 106-112 epoxide hydrolase 1 Homo sapiens 0-28 15150264-1 2004 Microsomal epoxide hydrolase (mEH) plays a central role in xenobiotic metabolism as well as mediating the sodium-dependent uptake of bile acids into the liver, where these compounds regulate numerous biological processes such as cholesterol metabolism and hepatocyte signaling pathways. Bile Acids and Salts 133-143 epoxide hydrolase 1 Homo sapiens 0-28 15150264-1 2004 Microsomal epoxide hydrolase (mEH) plays a central role in xenobiotic metabolism as well as mediating the sodium-dependent uptake of bile acids into the liver, where these compounds regulate numerous biological processes such as cholesterol metabolism and hepatocyte signaling pathways. Cholesterol 229-240 epoxide hydrolase 1 Homo sapiens 0-28 15766072-1 2004 The authors investigated the property of cathodluminescence-like (CL-like) emission in the device of MEH-PPV sandwiched between two SiO2 layers. Silicon Dioxide 132-136 epoxide hydrolase 1 Homo sapiens 101-104 15760013-0 2004 [Electroluminescence property of MEH-PPV/ZnO nano-crystal structure]. Zinc Oxide 41-44 epoxide hydrolase 1 Homo sapiens 33-36 15760013-3 2004 And a new peak at 620 nm was found in the ITO/MEH-PPV/ZnO/Al structure"s electroluminescence spectrum, which should resulted from ZnO layer. Zinc Oxide 54-57 epoxide hydrolase 1 Homo sapiens 46-49 15760013-3 2004 And a new peak at 620 nm was found in the ITO/MEH-PPV/ZnO/Al structure"s electroluminescence spectrum, which should resulted from ZnO layer. Aluminum 58-60 epoxide hydrolase 1 Homo sapiens 46-49 15760013-3 2004 And a new peak at 620 nm was found in the ITO/MEH-PPV/ZnO/Al structure"s electroluminescence spectrum, which should resulted from ZnO layer. Zinc Oxide 130-133 epoxide hydrolase 1 Homo sapiens 46-49 15760013-4 2004 In addition, the turning-on voltage of the two-layer structure decreased from 9 V of the single layer structure to 4 V. From the I-V curve, the authors concluded that the emitting area was around the interface of MEH-PPV/ZnO and the combination area could shift with changing the voltage. Zinc Oxide 221-224 epoxide hydrolase 1 Homo sapiens 213-216 15379526-1 2004 Morphological effects in luminescence properties of a representative semiconducting polymer, poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene) (MEH-PPV), has recently attracted much attention. poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene) 93-151 epoxide hydrolase 1 Homo sapiens 153-156 15355699-0 2004 [Effect of genetic polymorphisms of microsomal epoxide hydrolase on urinary 1-hydroxypyrene levels in coke oven workers]. 1-hydroxypyrene 76-91 epoxide hydrolase 1 Homo sapiens 36-64 15256148-0 2004 [Relationship of genetic polymorphism of microsomal epoxide hydrolase with susceptibility of chronic benzene poisoning]. Benzene 101-108 epoxide hydrolase 1 Homo sapiens 41-69 15256148-1 2004 OBJECTIVE: To explore the relationship between genetic polymorphisms of microsomal epoxide hydrolase (mEH) and susceptibility of chronic benzene poisoning (BP). Benzene 137-144 epoxide hydrolase 1 Homo sapiens 72-100 15256148-1 2004 OBJECTIVE: To explore the relationship between genetic polymorphisms of microsomal epoxide hydrolase (mEH) and susceptibility of chronic benzene poisoning (BP). Benzo(a)pyrene 156-158 epoxide hydrolase 1 Homo sapiens 72-100 14726935-2 2004 The glutathione-S-transferases (GST) family and microsomal epoxide hydrolase (mEPHx) enzymes detoxify ROS, and genetic polymorphisms alter this detoxification. Reactive Oxygen Species 102-105 epoxide hydrolase 1 Homo sapiens 48-76 15053595-4 2004 The fluorescence (photoluminescence) of isolated MEH-PPV conjugated polymer molecules imbedded in the device was observed to exhibit diverse time- and electrical bias-dependent effects. Polymers 68-75 epoxide hydrolase 1 Homo sapiens 49-52 15036120-0 2004 Lack of increased genetic damage in 1,3-butadiene-exposed Chinese workers studied in relation to EPHX1 and GST genotypes. 1,3-butadiene 36-49 epoxide hydrolase 1 Homo sapiens 97-102 14984931-1 2004 Microsomal epoxide hydrolase (mEH) is a bifunctional protein that plays a crucial role in the metabolism of numerous xenobiotics as well as in mediating the hepatic sodium-dependent uptake of bile acids that are involved in numerous physiological processes including the regulation of cholesterol metabolism. Sodium 165-171 epoxide hydrolase 1 Homo sapiens 0-28 14984931-1 2004 Microsomal epoxide hydrolase (mEH) is a bifunctional protein that plays a crucial role in the metabolism of numerous xenobiotics as well as in mediating the hepatic sodium-dependent uptake of bile acids that are involved in numerous physiological processes including the regulation of cholesterol metabolism. Bile Acids and Salts 192-202 epoxide hydrolase 1 Homo sapiens 0-28 14984931-1 2004 Microsomal epoxide hydrolase (mEH) is a bifunctional protein that plays a crucial role in the metabolism of numerous xenobiotics as well as in mediating the hepatic sodium-dependent uptake of bile acids that are involved in numerous physiological processes including the regulation of cholesterol metabolism. Cholesterol 285-296 epoxide hydrolase 1 Homo sapiens 0-28 14751678-0 2004 Occupational exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 and GSTP1. Styrene 25-32 epoxide hydrolase 1 Homo sapiens 146-151 14669306-1 2003 AIM: To investigate the possible association of microsomal epoxide hydrolase (mEH) Tyr113His polymorphism with susceptibility to esophageal squamous cell carcinoma (ESCC) in a population of North China. tyr113his 83-92 epoxide hydrolase 1 Homo sapiens 48-76 14669306-8 2003 CONCLUSION: MEH Tyr113His polymorphism may not be used as a stratification marker in screening individuals at a high risk of ESCC. tyr113his 16-25 epoxide hydrolase 1 Homo sapiens 12-15 14624602-0 2003 Electrospun MEH-PPV/SBA-15 composite nanofibers using a dual syringe method. SBA-15 20-26 epoxide hydrolase 1 Homo sapiens 12-15 12655032-2 2003 Polymorphisms in human microsomal epoxide hydrolase (mEH) are associated with an increased risk of developing leukemia, specifically those associated with benzene. Benzene 155-162 epoxide hydrolase 1 Homo sapiens 23-51 12878321-1 2003 Microsomal epoxide hydrolase (mEH) is a bifunctional protein that plays a central role in carcinogen metabolism and is also able to mediate the sodium-dependent uptake of bile acids into hepatocytes. Sodium 144-150 epoxide hydrolase 1 Homo sapiens 0-28 12878321-1 2003 Microsomal epoxide hydrolase (mEH) is a bifunctional protein that plays a central role in carcinogen metabolism and is also able to mediate the sodium-dependent uptake of bile acids into hepatocytes. Bile Acids and Salts 171-181 epoxide hydrolase 1 Homo sapiens 0-28 12605384-0 2003 Variability in human sensitivity to 1,3-butadiene: Influence of the allelic variants of the microsomal epoxide hydrolase gene. 1,3-butadiene 36-49 epoxide hydrolase 1 Homo sapiens 92-120 12745870-8 2003 An intermediary metabolite, epoxy-2n-propylquinoline, formed by CYP was also biotransformed by microsomal epoxide hydrolase into dihydroxy-2n-propylquinoline. epoxy-2n-propylquinoline 28-52 epoxide hydrolase 1 Homo sapiens 95-123 12745870-8 2003 An intermediary metabolite, epoxy-2n-propylquinoline, formed by CYP was also biotransformed by microsomal epoxide hydrolase into dihydroxy-2n-propylquinoline. dihydroxy-2n-propylquinoline 129-157 epoxide hydrolase 1 Homo sapiens 95-123 12745870-15 2003 The results indicate that 2nPQ metabolites are 3"- and 1"-hydroxylated by human liver microsomes and an epoxy-2n-propylquinoline is biotransformed into a dihydroxy-2n-propylquinoline by microsomal epoxide hydrolase. 2-propylquinoline 26-30 epoxide hydrolase 1 Homo sapiens 186-214 12745870-15 2003 The results indicate that 2nPQ metabolites are 3"- and 1"-hydroxylated by human liver microsomes and an epoxy-2n-propylquinoline is biotransformed into a dihydroxy-2n-propylquinoline by microsomal epoxide hydrolase. epoxy-2n-propylquinoline 104-128 epoxide hydrolase 1 Homo sapiens 186-214 12745870-15 2003 The results indicate that 2nPQ metabolites are 3"- and 1"-hydroxylated by human liver microsomes and an epoxy-2n-propylquinoline is biotransformed into a dihydroxy-2n-propylquinoline by microsomal epoxide hydrolase. dihydroxy-2n-propylquinoline 154-182 epoxide hydrolase 1 Homo sapiens 186-214 12605384-2 2003 In humans, these epoxides are detoxified predominantly by hydrolysis, a reaction mediated by the microsomal epoxide hydrolase (mEH) enzyme. Epoxy Compounds 17-25 epoxide hydrolase 1 Homo sapiens 97-125 12938356-1 2002 In this paper, we studied the optical properties of the charge transfer system in poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene](MEH-PPV), which was doped by C60 with different consistence, by means of ultraviolet-visible absorption spectrum, steady-state photoluminescence (PL) and time-resolved photoluminescence (TRPL). poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] 82-142 epoxide hydrolase 1 Homo sapiens 143-146 12234472-0 2002 Detection of polymorphisms at exons 3 (Tyr113-->His) and 4 (His139-->Arg) of the microsomal epoxide hydrolase gene using fluorescence PCR method combined with melting curves analysis. Histidine 51-54 epoxide hydrolase 1 Homo sapiens 87-115 12234472-0 2002 Detection of polymorphisms at exons 3 (Tyr113-->His) and 4 (His139-->Arg) of the microsomal epoxide hydrolase gene using fluorescence PCR method combined with melting curves analysis. Arginine 75-78 epoxide hydrolase 1 Homo sapiens 87-115 12029283-3 2002 RESULTS: At Ephx1 (microsomal epoxide hydrolase) codon 113, an overrepresentation of the greater activity genotype (Tyr/Tyr) was observed for male ever-smokers alone, both male and female ever-smokers, female never-smokers alone, and in both male and female never-smokers, compared with a control population sample. Tyrosine 116-119 epoxide hydrolase 1 Homo sapiens 12-17 12029283-3 2002 RESULTS: At Ephx1 (microsomal epoxide hydrolase) codon 113, an overrepresentation of the greater activity genotype (Tyr/Tyr) was observed for male ever-smokers alone, both male and female ever-smokers, female never-smokers alone, and in both male and female never-smokers, compared with a control population sample. Tyrosine 116-119 epoxide hydrolase 1 Homo sapiens 19-47 11752683-0 2002 Expression of human microsomal epoxide hydrolase in Saccharomyces cerevisiae reveals a functional role in aflatoxin B1 detoxification. Aflatoxin B1 106-118 epoxide hydrolase 1 Homo sapiens 20-48 12029283-3 2002 RESULTS: At Ephx1 (microsomal epoxide hydrolase) codon 113, an overrepresentation of the greater activity genotype (Tyr/Tyr) was observed for male ever-smokers alone, both male and female ever-smokers, female never-smokers alone, and in both male and female never-smokers, compared with a control population sample. Tyrosine 120-123 epoxide hydrolase 1 Homo sapiens 12-17 12029283-3 2002 RESULTS: At Ephx1 (microsomal epoxide hydrolase) codon 113, an overrepresentation of the greater activity genotype (Tyr/Tyr) was observed for male ever-smokers alone, both male and female ever-smokers, female never-smokers alone, and in both male and female never-smokers, compared with a control population sample. Tyrosine 120-123 epoxide hydrolase 1 Homo sapiens 19-47 12029283-7 2002 CONCLUSION: The Ephx1 codon 113 Tyr/Tyr variant, as well as homozygosity for the GSTT1 null allele, is associated with oropharyngeal carcinogenesis. Tyrosine 32-35 epoxide hydrolase 1 Homo sapiens 16-21 12029283-7 2002 CONCLUSION: The Ephx1 codon 113 Tyr/Tyr variant, as well as homozygosity for the GSTT1 null allele, is associated with oropharyngeal carcinogenesis. Tyrosine 36-39 epoxide hydrolase 1 Homo sapiens 16-21 11849215-4 2002 We tested the hypothesis that smoking as well as genetic polymorphisms in the microsomal epoxide hydrolase gene (HYL1), an enzyme involved in benzene metabolism, could be risk factors for AML with defined chromosomal abnormalities. Benzene 142-149 epoxide hydrolase 1 Homo sapiens 78-106 11489754-1 2001 Microsomal epoxide hydrolase (mEH) metabolizes polycyclic aromatic hydrocarbons, carcinogens found in cigarette smoke and cooked meat. Polycyclic Aromatic Hydrocarbons 47-79 epoxide hydrolase 1 Homo sapiens 0-28 11597790-1 2001 Human microsomal epoxide hydrolase (mEH) catalyzes a key step in the biotransformation of benzo[a]pyrene that yields the highly mutagenic (+)-anti-7,8-diol-9,10 epoxide (BPDE). Benzo(a)pyrene 90-104 epoxide hydrolase 1 Homo sapiens 6-34 11597790-1 2001 Human microsomal epoxide hydrolase (mEH) catalyzes a key step in the biotransformation of benzo[a]pyrene that yields the highly mutagenic (+)-anti-7,8-diol-9,10 epoxide (BPDE). 7,8-diol-9,10 epoxide 147-168 epoxide hydrolase 1 Homo sapiens 6-34 11597790-1 2001 Human microsomal epoxide hydrolase (mEH) catalyzes a key step in the biotransformation of benzo[a]pyrene that yields the highly mutagenic (+)-anti-7,8-diol-9,10 epoxide (BPDE). 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 170-174 epoxide hydrolase 1 Homo sapiens 6-34 11597790-8 2001 The 113 Tyr/Tyr EPHX1 encodes for a high-activity mEH. Tyrosine 8-11 epoxide hydrolase 1 Homo sapiens 16-21 11721893-3 2001 Images of MEH-PPV were obtained with comparable spatial resolution in both air and water. Water 83-88 epoxide hydrolase 1 Homo sapiens 10-13 11692079-3 2001 The microsomal (EPHX1) and soluble (EPHX2) epoxide hydrolases function to regulate the oxidation status of a wide range of xenobiotic- and lipid-derived substrates; therefore, interindividual variation in these pathways may mitigate epoxide-related cellular injury. Epoxy Compounds 43-50 epoxide hydrolase 1 Homo sapiens 16-21 23889309-7 2001 Logistic regression analysis indicated that occupational exposure, wild-type CYP1A1*1/*1 allele and the combination of GSTM1 null genotype+EHPX genotypes associated with predicted low enzyme activity were significant predictors of BPDE-SA adducts. bpde-sa 231-238 epoxide hydrolase 1 Homo sapiens 139-143 11437638-5 2001 The results indicate enzymatically catalyzed GSH conjugation via cytosolic glutathione S-transferase (cGST) and hydrolysis via microsomal epoxide hydrolase (mEH) occur in both rodents and humans. Glutathione 45-48 epoxide hydrolase 1 Homo sapiens 127-155 11238181-0 2001 Human sensitivity to 1,3-butadiene: role of microsomal epoxide hydrolase polymorphisms. 1,3-butadiene 21-34 epoxide hydrolase 1 Homo sapiens 44-72 11764998-13 2001 There is now evidence that human microsomal epoxide hydrolase (mEH) could play a role in protecting human DNA from the genotoxic effects of AFB, although the importance of this detoxification pathway, relative to mu class GSTs, remains to be elucidated. afb 140-143 epoxide hydrolase 1 Homo sapiens 33-61 23889309-0 2001 Benzo(a)pyrene diolepoxide adducts to albumin in workers exposed to polycyclic aromatic hydrocarbons: association with specific CYP1A1, GSTM1, GSTP1 and EHPX genotypes. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 0-26 epoxide hydrolase 1 Homo sapiens 153-157 23889309-0 2001 Benzo(a)pyrene diolepoxide adducts to albumin in workers exposed to polycyclic aromatic hydrocarbons: association with specific CYP1A1, GSTM1, GSTP1 and EHPX genotypes. Polycyclic Aromatic Hydrocarbons 68-100 epoxide hydrolase 1 Homo sapiens 153-157 11471167-4 2001 Microsomal epoxide hydrolase (mEH; gene symbol EPHX1) catalyzes hydrolysis of epoxides. Epoxy Compounds 78-86 epoxide hydrolase 1 Homo sapiens 0-28 11471167-4 2001 Microsomal epoxide hydrolase (mEH; gene symbol EPHX1) catalyzes hydrolysis of epoxides. Epoxy Compounds 78-86 epoxide hydrolase 1 Homo sapiens 47-52 11471167-6 2001 Recent studies suggest an association between the EPHX1 codon 113 polymorphism or homozygous null GSTM1 allele and the risk of carcinogenesis, emphysema, phenytoin-associated oral clefting, and the risk of spontaneous abortion. Phenytoin 154-163 epoxide hydrolase 1 Homo sapiens 50-55 11758809-1 2001 Microsomal epoxide hydrolase is a biotransformation enzyme which is involved in the hydrolysis of various epoxides and epoxide intermediates. Epoxy Compounds 106-114 epoxide hydrolase 1 Homo sapiens 0-28 11255266-1 2001 Functional significance has been demonstrated in vitro for the exon 3 T-->C Tyr113His amino acid substitution polymorphism of the microsomal epoxide hydrolase (EPHX) gene. tyr113his amino acid 79-99 epoxide hydrolase 1 Homo sapiens 133-161 11134189-0 2001 Microsomal epoxide hydrolase expression as a predictor of tamoxifen response in primary breast cancer: a retrospective exploratory study with long-term follow-up. Tamoxifen 58-67 epoxide hydrolase 1 Homo sapiens 0-28 11255266-1 2001 Functional significance has been demonstrated in vitro for the exon 3 T-->C Tyr113His amino acid substitution polymorphism of the microsomal epoxide hydrolase (EPHX) gene. tyr113his amino acid 79-99 epoxide hydrolase 1 Homo sapiens 163-167 11191882-3 2000 We have found the following frequencies of mutated alleles: CYP1A1-m2, 0.097; CYP2E1-C, 0.077; CYP2E1-c2, 0.023; EPHX(exon 3)-His, 0.381; EPHX(exon 4)-Arg, 0.198; GSTM1-null, 0.51; GSTP1-Val, 0.3; GSTT1-null, 0.164. Histidine 126-129 epoxide hydrolase 1 Homo sapiens 113-117 11191882-3 2000 We have found the following frequencies of mutated alleles: CYP1A1-m2, 0.097; CYP2E1-C, 0.077; CYP2E1-c2, 0.023; EPHX(exon 3)-His, 0.381; EPHX(exon 4)-Arg, 0.198; GSTM1-null, 0.51; GSTP1-Val, 0.3; GSTT1-null, 0.164. Arginine 151-154 epoxide hydrolase 1 Homo sapiens 113-117 11027327-1 2000 Single molecule confocal fluorescence microscopy was used to perform photoluminescence spectroscopy on single, isolated molecules of the conjugated polymer poly[2-methoxy, 5-(2"-ethyl-hexyloxy)-p-phenylene-vinylene] (MEH-PPV). Polymers 148-155 epoxide hydrolase 1 Homo sapiens 217-220 11027327-1 2000 Single molecule confocal fluorescence microscopy was used to perform photoluminescence spectroscopy on single, isolated molecules of the conjugated polymer poly[2-methoxy, 5-(2"-ethyl-hexyloxy)-p-phenylene-vinylene] (MEH-PPV). poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 156-215 epoxide hydrolase 1 Homo sapiens 217-220 10751038-0 2000 Structure activity relationship of human microsomal epoxide hydrolase inhibition by amide and acid analogues of valproic acid. Amides 84-89 epoxide hydrolase 1 Homo sapiens 41-69 10720753-1 2000 Microsomal epoxide hydrolase is a critical biotransformation enzyme that catalyzes the conversion of a broad array of xenobiotic epoxide substrates to more polar diol metabolites. xenobiotic epoxide 118-136 epoxide hydrolase 1 Homo sapiens 0-28 10720753-1 2000 Microsomal epoxide hydrolase is a critical biotransformation enzyme that catalyzes the conversion of a broad array of xenobiotic epoxide substrates to more polar diol metabolites. diol 162-166 epoxide hydrolase 1 Homo sapiens 0-28 10673439-9 2000 CONCLUSIONS: The Aspergillus enzyme provides the first structure of an epoxide hydrolase with strong relationships to the most important enzyme of human epoxide metabolism, the microsomal epoxide hydrolase. Epoxy Compounds 71-78 epoxide hydrolase 1 Homo sapiens 177-205 10751038-1 2000 PURPOSE: The purpose of this study was to evaluate the in vitro inhibitory potency of various amide analogues and derivatives of valproic acid toward human microsomal epoxide hydrolase (mEH). Amides 94-99 epoxide hydrolase 1 Homo sapiens 156-184 10751038-1 2000 PURPOSE: The purpose of this study was to evaluate the in vitro inhibitory potency of various amide analogues and derivatives of valproic acid toward human microsomal epoxide hydrolase (mEH). Valproic Acid 129-142 epoxide hydrolase 1 Homo sapiens 156-184 10958774-0 2000 Unmasking electronic energy transfer of conjugated polymers by suppression of O(2) quenching The photochemistry of poly[2-methoxy, 5-(2"-ethyl-hexyloxy)-p-phenylene-vinylene] (MEH-PPV) has been found to be highly dependent on the presence of O(2), which increases singlet exciton quenching dramatically. Polymers 51-59 epoxide hydrolase 1 Homo sapiens 176-179 10958774-0 2000 Unmasking electronic energy transfer of conjugated polymers by suppression of O(2) quenching The photochemistry of poly[2-methoxy, 5-(2"-ethyl-hexyloxy)-p-phenylene-vinylene] (MEH-PPV) has been found to be highly dependent on the presence of O(2), which increases singlet exciton quenching dramatically. o(2) 78-82 epoxide hydrolase 1 Homo sapiens 176-179 10958774-0 2000 Unmasking electronic energy transfer of conjugated polymers by suppression of O(2) quenching The photochemistry of poly[2-methoxy, 5-(2"-ethyl-hexyloxy)-p-phenylene-vinylene] (MEH-PPV) has been found to be highly dependent on the presence of O(2), which increases singlet exciton quenching dramatically. poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 115-173 epoxide hydrolase 1 Homo sapiens 176-179 10958774-0 2000 Unmasking electronic energy transfer of conjugated polymers by suppression of O(2) quenching The photochemistry of poly[2-methoxy, 5-(2"-ethyl-hexyloxy)-p-phenylene-vinylene] (MEH-PPV) has been found to be highly dependent on the presence of O(2), which increases singlet exciton quenching dramatically. o(2) 242-246 epoxide hydrolase 1 Homo sapiens 176-179 10958774-1 2000 Spectroscopy on isolated single molecules of MEH-PPV in polycarbonate films that exclude O(2) reveals two distinct polymer conformations with fluorescence maxima near 555 and 580 nanometers wavelength, respectively. o(2) 89-93 epoxide hydrolase 1 Homo sapiens 45-48 10958774-1 2000 Spectroscopy on isolated single molecules of MEH-PPV in polycarbonate films that exclude O(2) reveals two distinct polymer conformations with fluorescence maxima near 555 and 580 nanometers wavelength, respectively. Polymers 115-122 epoxide hydrolase 1 Homo sapiens 45-48 10751038-0 2000 Structure activity relationship of human microsomal epoxide hydrolase inhibition by amide and acid analogues of valproic acid. Valproic Acid 112-125 epoxide hydrolase 1 Homo sapiens 41-69 9763414-8 1998 Mechanistic studies using cDNA-expressed CYP1A2 microsomes fortified with microsomal epoxide hydrolase revealed that all three bropirimine oxidative metabolites appear to be the result of a common arene oxide, which serves as a substrate for microsomal epoxide hydrolase to generate the dihydrodiol or rearranges to yield p- and m-hydroxybropirimine. bropirimine 127-138 epoxide hydrolase 1 Homo sapiens 74-102 10576413-1 1999 Microsomal epoxide hydrolase catalyses the hydrolysis of epoxides to water-soluble trans-dihydrodiols. Epoxy Compounds 57-65 epoxide hydrolase 1 Homo sapiens 0-28 10576413-1 1999 Microsomal epoxide hydrolase catalyses the hydrolysis of epoxides to water-soluble trans-dihydrodiols. Water 69-74 epoxide hydrolase 1 Homo sapiens 0-28 10576413-1 1999 Microsomal epoxide hydrolase catalyses the hydrolysis of epoxides to water-soluble trans-dihydrodiols. trans-dihydrodiols 83-101 epoxide hydrolase 1 Homo sapiens 0-28 9763414-8 1998 Mechanistic studies using cDNA-expressed CYP1A2 microsomes fortified with microsomal epoxide hydrolase revealed that all three bropirimine oxidative metabolites appear to be the result of a common arene oxide, which serves as a substrate for microsomal epoxide hydrolase to generate the dihydrodiol or rearranges to yield p- and m-hydroxybropirimine. bropirimine 127-138 epoxide hydrolase 1 Homo sapiens 242-270 9763414-8 1998 Mechanistic studies using cDNA-expressed CYP1A2 microsomes fortified with microsomal epoxide hydrolase revealed that all three bropirimine oxidative metabolites appear to be the result of a common arene oxide, which serves as a substrate for microsomal epoxide hydrolase to generate the dihydrodiol or rearranges to yield p- and m-hydroxybropirimine. Benzene oxide 197-208 epoxide hydrolase 1 Homo sapiens 74-102 9763414-8 1998 Mechanistic studies using cDNA-expressed CYP1A2 microsomes fortified with microsomal epoxide hydrolase revealed that all three bropirimine oxidative metabolites appear to be the result of a common arene oxide, which serves as a substrate for microsomal epoxide hydrolase to generate the dihydrodiol or rearranges to yield p- and m-hydroxybropirimine. Benzene oxide 197-208 epoxide hydrolase 1 Homo sapiens 242-270 9485442-1 1998 Microsomal epoxide hydrolase (MEH) is a member of the alpha/beta-hydrolase fold family of enzymes, each of which has a catalytic triad consisting of a nucleophile involved in the formation of a covalent intermediate and a general base and charge relay carboxylate that catalyze the hydrolysis of the intermediate. carboxylate 252-263 epoxide hydrolase 1 Homo sapiens 0-28 9485442-1 1998 Microsomal epoxide hydrolase (MEH) is a member of the alpha/beta-hydrolase fold family of enzymes, each of which has a catalytic triad consisting of a nucleophile involved in the formation of a covalent intermediate and a general base and charge relay carboxylate that catalyze the hydrolysis of the intermediate. carboxylate 252-263 epoxide hydrolase 1 Homo sapiens 30-33 9485442-2 1998 The rate-limiting step in the catalytic mechanism of MEH is hydrolysis of the ester intermediate. Esters 78-83 epoxide hydrolase 1 Homo sapiens 53-56 9525271-1 1998 Microsomal epoxide hydrolase (mEH) catalyses the hydrolysis of xenobiotic epoxides, including various epoxide derivatives of the procarcinogenic polyaromatic hydrocarbons. xenobiotic epoxides 63-82 epoxide hydrolase 1 Homo sapiens 0-28 9525271-1 1998 Microsomal epoxide hydrolase (mEH) catalyses the hydrolysis of xenobiotic epoxides, including various epoxide derivatives of the procarcinogenic polyaromatic hydrocarbons. polyaromatic hydrocarbons 145-170 epoxide hydrolase 1 Homo sapiens 0-28 9435884-0 1997 Recombinant expression of human microsomal epoxide hydrolase protects V79 Chinese hamster cells from styrene oxide- but not from ethylene oxide-induced DNA strand breaks. styrene oxide 101-114 epoxide hydrolase 1 Homo sapiens 32-60 9280411-1 1997 Incubations of butadiene monoxide (BMO) with mouse, rat, and human liver microsomes or cDNA-expressed human microsomal epoxide hydrolase led to 3-buten-1,2-diol (BDD) detection; the BDD peak exhibited a GC/MS fragmentation pattern similar to that of reference material. 3,4-epoxy-1-butene 15-33 epoxide hydrolase 1 Homo sapiens 108-136 9280411-1 1997 Incubations of butadiene monoxide (BMO) with mouse, rat, and human liver microsomes or cDNA-expressed human microsomal epoxide hydrolase led to 3-buten-1,2-diol (BDD) detection; the BDD peak exhibited a GC/MS fragmentation pattern similar to that of reference material. 3,4-epoxy-1-butene 35-38 epoxide hydrolase 1 Homo sapiens 108-136 9280411-1 1997 Incubations of butadiene monoxide (BMO) with mouse, rat, and human liver microsomes or cDNA-expressed human microsomal epoxide hydrolase led to 3-buten-1,2-diol (BDD) detection; the BDD peak exhibited a GC/MS fragmentation pattern similar to that of reference material. 3-buten-1,2-diol 144-160 epoxide hydrolase 1 Homo sapiens 108-136 9280411-1 1997 Incubations of butadiene monoxide (BMO) with mouse, rat, and human liver microsomes or cDNA-expressed human microsomal epoxide hydrolase led to 3-buten-1,2-diol (BDD) detection; the BDD peak exhibited a GC/MS fragmentation pattern similar to that of reference material. 7,7'-dimethoxy-(4,4'-bi-1,3-benzodioxole)-5,5'-dicarboxylic acid dimethyl ester 162-165 epoxide hydrolase 1 Homo sapiens 108-136 9280411-1 1997 Incubations of butadiene monoxide (BMO) with mouse, rat, and human liver microsomes or cDNA-expressed human microsomal epoxide hydrolase led to 3-buten-1,2-diol (BDD) detection; the BDD peak exhibited a GC/MS fragmentation pattern similar to that of reference material. 7,7'-dimethoxy-(4,4'-bi-1,3-benzodioxole)-5,5'-dicarboxylic acid dimethyl ester 182-185 epoxide hydrolase 1 Homo sapiens 108-136 9224217-2 1997 PAH are converted to carcinogenic molecules through a combination of monoxygenation by cytochrome p450 (CYP) enzymes in the presence of NADPH oxidoreductase (OR) and hydrolysis by microsomal epoxide hydrolase (mEH). Polycyclic Aromatic Hydrocarbons 0-3 epoxide hydrolase 1 Homo sapiens 180-208 9406998-1 1997 Human microsomal epoxide hydrolase (HYL1) plays an important role in the detoxification of environmental compounds and drugs, such as the aromatic anticonvulsants phenytoin, carbamazepine, and phenobarbital, by converting their P450-generated epoxide metabolites into nontoxic diols. Phenytoin 163-172 epoxide hydrolase 1 Homo sapiens 6-34 9406998-1 1997 Human microsomal epoxide hydrolase (HYL1) plays an important role in the detoxification of environmental compounds and drugs, such as the aromatic anticonvulsants phenytoin, carbamazepine, and phenobarbital, by converting their P450-generated epoxide metabolites into nontoxic diols. Carbamazepine 174-187 epoxide hydrolase 1 Homo sapiens 6-34 9406998-1 1997 Human microsomal epoxide hydrolase (HYL1) plays an important role in the detoxification of environmental compounds and drugs, such as the aromatic anticonvulsants phenytoin, carbamazepine, and phenobarbital, by converting their P450-generated epoxide metabolites into nontoxic diols. Phenobarbital 193-206 epoxide hydrolase 1 Homo sapiens 6-34 9406998-1 1997 Human microsomal epoxide hydrolase (HYL1) plays an important role in the detoxification of environmental compounds and drugs, such as the aromatic anticonvulsants phenytoin, carbamazepine, and phenobarbital, by converting their P450-generated epoxide metabolites into nontoxic diols. diols 277-282 epoxide hydrolase 1 Homo sapiens 6-34 9435884-3 1997 In order to study the role of human microsomal epoxide hydrolase (hmEH) in protecting cells against genotoxicity of styrene 7,8-oxide and ethylene oxide, we expressed the cDNA of hmEH in V79 Chinese hamster cells. styrene oxide 116-133 epoxide hydrolase 1 Homo sapiens 36-64 9435884-7 1997 The protection against styrene 7,8-oxide genotoxicity in 92hmEH-V79 cells could be abolished by addition of valpromide, a selective inhibitor of microsomal epoxide hydrolase. styrene oxide 23-40 epoxide hydrolase 1 Homo sapiens 145-173 9435884-7 1997 The protection against styrene 7,8-oxide genotoxicity in 92hmEH-V79 cells could be abolished by addition of valpromide, a selective inhibitor of microsomal epoxide hydrolase. dipropylacetamide 108-118 epoxide hydrolase 1 Homo sapiens 145-173 9014198-1 1996 The metabolism of benzo[a]pyrene (B[a]P) and its proximate mutagen B[a]P-7,8-dihydrodiol (7,8-diol) was investigated in the presence of human microsomal epoxide hydrolase and P450 1A1, 1A2, 2C8, 2C9, 2C18, 2C19, 2D6 and 3A4 expressed in the yeast Saccharomyces cerevisiae. Benzo(a)pyrene 18-32 epoxide hydrolase 1 Homo sapiens 142-170 9014198-1 1996 The metabolism of benzo[a]pyrene (B[a]P) and its proximate mutagen B[a]P-7,8-dihydrodiol (7,8-diol) was investigated in the presence of human microsomal epoxide hydrolase and P450 1A1, 1A2, 2C8, 2C9, 2C18, 2C19, 2D6 and 3A4 expressed in the yeast Saccharomyces cerevisiae. 7,8-dihydrodiol 73-88 epoxide hydrolase 1 Homo sapiens 142-170 9014198-1 1996 The metabolism of benzo[a]pyrene (B[a]P) and its proximate mutagen B[a]P-7,8-dihydrodiol (7,8-diol) was investigated in the presence of human microsomal epoxide hydrolase and P450 1A1, 1A2, 2C8, 2C9, 2C18, 2C19, 2D6 and 3A4 expressed in the yeast Saccharomyces cerevisiae. 7,8-diol 90-98 epoxide hydrolase 1 Homo sapiens 142-170 8819481-1 1996 Microsomal epoxide hydrolase (HYL1) is a single-gene enzyme responsible for the hydrolysis of epoxides derived from the oxidative metabolism of xenobiotics. Epoxy Compounds 94-102 epoxide hydrolase 1 Homo sapiens 0-28 8824525-6 1996 A cDNA-expressed human microsomal epoxide hydrolase, however, efficiently converted the epoxide to the diol and the microsomal epoxide inhibitor cyclohexene oxide inhibited quinoline-5,6-diol formation in rat liver microsomes. diol 103-107 epoxide hydrolase 1 Homo sapiens 23-51 8824525-6 1996 A cDNA-expressed human microsomal epoxide hydrolase, however, efficiently converted the epoxide to the diol and the microsomal epoxide inhibitor cyclohexene oxide inhibited quinoline-5,6-diol formation in rat liver microsomes. cyclohexene oxide 145-162 epoxide hydrolase 1 Homo sapiens 23-51 8824525-6 1996 A cDNA-expressed human microsomal epoxide hydrolase, however, efficiently converted the epoxide to the diol and the microsomal epoxide inhibitor cyclohexene oxide inhibited quinoline-5,6-diol formation in rat liver microsomes. 5,6-Quinolinediol 173-191 epoxide hydrolase 1 Homo sapiens 23-51 8569695-6 1996 Expressed human microsomal epoxide hydrolase and HLM catalyzed the attack of water predominantly (approximately 96%) at C5 of the 5R,6S-oxide, whereas 5S,6R-oxide was attacked less selectivity (approximately 60% at C5). 5s,6r-oxide 151-162 epoxide hydrolase 1 Homo sapiens 16-44 7503783-0 1995 Genetic analysis of microsomal epoxide hydrolase in patients with carbamazepine hypersensitivity. Carbamazepine 66-79 epoxide hydrolase 1 Homo sapiens 20-48 8569695-1 1996 In the present study, we studied the regioselectivity and stereoselectivity of human microsomal epoxide hydrolase-catalyzed hydration of the enantiomers of the polycyclic aza-aromatic hydrocarbon K-region oxide, 7-methylbenz[c]acridine-5,6-oxide. aza-aromatic hydrocarbon k-region oxide 171-210 epoxide hydrolase 1 Homo sapiens 85-113 8569695-1 1996 In the present study, we studied the regioselectivity and stereoselectivity of human microsomal epoxide hydrolase-catalyzed hydration of the enantiomers of the polycyclic aza-aromatic hydrocarbon K-region oxide, 7-methylbenz[c]acridine-5,6-oxide. 7-methylbenz(c)acridine-5,6-oxide 212-245 epoxide hydrolase 1 Homo sapiens 85-113 8569695-2 1996 We used a human microsomal epoxide hydrolase cDNA amplified from a liver cDNA library and expressed in COS-7 cells. carbonyl sulfide 103-106 epoxide hydrolase 1 Homo sapiens 16-44 8569695-4 1996 The determination of the apparent Michaelis-Menten kinetic constants revealed that microsomal epoxide hydrolase, regardless of the source, exhibited enantioselectivity, with the 5S,6R-oxide being the preferred substrate. CHEMBL3739852 178-180 epoxide hydrolase 1 Homo sapiens 83-111 8569695-4 1996 The determination of the apparent Michaelis-Menten kinetic constants revealed that microsomal epoxide hydrolase, regardless of the source, exhibited enantioselectivity, with the 5S,6R-oxide being the preferred substrate. 6r-oxide 181-189 epoxide hydrolase 1 Homo sapiens 83-111 8569695-6 1996 Expressed human microsomal epoxide hydrolase and HLM catalyzed the attack of water predominantly (approximately 96%) at C5 of the 5R,6S-oxide, whereas 5S,6R-oxide was attacked less selectivity (approximately 60% at C5). Water 77-82 epoxide hydrolase 1 Homo sapiens 16-44 8569695-6 1996 Expressed human microsomal epoxide hydrolase and HLM catalyzed the attack of water predominantly (approximately 96%) at C5 of the 5R,6S-oxide, whereas 5S,6R-oxide was attacked less selectivity (approximately 60% at C5). 5r,6s-oxide 130-141 epoxide hydrolase 1 Homo sapiens 16-44 7503783-11 1995 The results of this study suggest that a single mutation within the coding region of the microsomal epoxide hydrolase gene cannot be the sole determinant of the predisposition to carbamazepine hypersensitivity. Carbamazepine 179-192 epoxide hydrolase 1 Homo sapiens 89-117 7503784-0 1995 Kinetic parameters of lymphocyte microsomal epoxide hydrolase in carbamazepine hypersensitive patients. Carbamazepine 65-78 epoxide hydrolase 1 Homo sapiens 33-61 7503784-2 1995 Idiosyncratic hypersensitivity reactions with carbamazepine have been postulated to be due to a deficiency of microsomal epoxide hydrolase (HYL1), although this is based on indirect evidence. Carbamazepine 46-59 epoxide hydrolase 1 Homo sapiens 110-138 7917777-0 1994 Lymphocyte microsomal epoxide hydrolase in patients on carbamazepine therapy. Carbamazepine 55-68 epoxide hydrolase 1 Homo sapiens 11-39 7769232-1 1995 Microsomal epoxide hydrolase is a xenobiotic metabolizing enzyme that catalyzes the conversion of toxic and carcinogenic epoxides to less toxic dihydrodiols. Epoxy Compounds 121-129 epoxide hydrolase 1 Homo sapiens 0-28 7769232-1 1995 Microsomal epoxide hydrolase is a xenobiotic metabolizing enzyme that catalyzes the conversion of toxic and carcinogenic epoxides to less toxic dihydrodiols. trans-1,2-dihydro-1,2-naphthalenediol 144-156 epoxide hydrolase 1 Homo sapiens 0-28 8585611-1 1995 The microfluorometric assay, suitable for measuring microsomal epoxide hydrolase activity in cultured cells, is based on the conversion of benzo[a]pyrene-7,8-epoxide to the corresponding trans-benzo[a]pyrene-7,8-dihydrodiol, a compound that fluoresces at 403 nm when excited at 365 nm. benzo(a)pyrene 7,8-oxide 139-165 epoxide hydrolase 1 Homo sapiens 52-80 8585611-1 1995 The microfluorometric assay, suitable for measuring microsomal epoxide hydrolase activity in cultured cells, is based on the conversion of benzo[a]pyrene-7,8-epoxide to the corresponding trans-benzo[a]pyrene-7,8-dihydrodiol, a compound that fluoresces at 403 nm when excited at 365 nm. benzo(a)pyrene 7,8-dihydrodiol 187-223 epoxide hydrolase 1 Homo sapiens 52-80 7611390-1 1995 Nitrogen (N) balance, fed-state leucine kinetics, and urinary 3-methylhistidine (3-MeH) excretion were examined in 12 men and women, aged 56-80 yr, before and during 12 wk of resistance training (RT). 3-methylhistidine 62-79 epoxide hydrolase 1 Homo sapiens 83-86 7835893-1 1994 Human microsomal epoxide hydrolase (mEH) is a xenobiotic-metabolizing enzyme that detoxifies reactive epoxides to more water soluble dihydrodiol compounds. reactive epoxides 93-110 epoxide hydrolase 1 Homo sapiens 6-34 7835893-1 1994 Human microsomal epoxide hydrolase (mEH) is a xenobiotic-metabolizing enzyme that detoxifies reactive epoxides to more water soluble dihydrodiol compounds. Water 119-124 epoxide hydrolase 1 Homo sapiens 6-34 7835893-1 1994 Human microsomal epoxide hydrolase (mEH) is a xenobiotic-metabolizing enzyme that detoxifies reactive epoxides to more water soluble dihydrodiol compounds. trans-1,2-dihydro-1,2-naphthalenediol 133-144 epoxide hydrolase 1 Homo sapiens 6-34 7917777-2 1994 In order to determine whether carbamazepine is an inducer of lymphocyte microsomal epoxide hydrolase, the activity of the enzyme has been measured in the lymphocytes of 40 patients on continuous drug therapy using [3H]-cis stilbene oxide as a substrate. Carbamazepine 30-43 epoxide hydrolase 1 Homo sapiens 72-100 7917777-12 1994 Lymphocyte microsomal epoxide hydrolase activity was marginally, but significantly (P = 0.02) higher in the patients (28.4 pmol diol min-1 mg-1 protein) than in drug-free controls (23.4 pmol diol min-1 mg-1 protein (95% CI for difference -9 to -0.8)). diol 128-132 epoxide hydrolase 1 Homo sapiens 11-39 7917777-14 1994 The results indicate that at concentrations of carbamazepine which produce marked induction of hepatic CYP3A, an enzyme involved in the metabolism and bioactivation of carbamazepine, there is only a slight increase in lymphocyte microsomal epoxide hydrolase. Carbamazepine 47-60 epoxide hydrolase 1 Homo sapiens 229-257 7920694-2 1994 These drugs are thought to be activated to potentially reactive arene oxide (epoxide) metabolites by cytochrome P450-dependent monooxygenation, while liver microsomal epoxide hydrolase (mEH) plays a detoxifying role by converting such reactive intermediates to non-toxic dihydrodiols. Benzene oxide 64-75 epoxide hydrolase 1 Homo sapiens 156-184 7920694-2 1994 These drugs are thought to be activated to potentially reactive arene oxide (epoxide) metabolites by cytochrome P450-dependent monooxygenation, while liver microsomal epoxide hydrolase (mEH) plays a detoxifying role by converting such reactive intermediates to non-toxic dihydrodiols. trans-1,2-dihydro-1,2-naphthalenediol 271-283 epoxide hydrolase 1 Homo sapiens 156-184 7516776-1 1994 Human microsomal epoxide hydrolase (mEH) is a biotransformation enzyme that metabolizes reactive epoxide intermediates to more water-soluble trans-dihydrodiol derivatives. Water 127-132 epoxide hydrolase 1 Homo sapiens 6-34 7516776-1 1994 Human microsomal epoxide hydrolase (mEH) is a biotransformation enzyme that metabolizes reactive epoxide intermediates to more water-soluble trans-dihydrodiol derivatives. trans-dihydrodiol 141-158 epoxide hydrolase 1 Homo sapiens 6-34 8313504-0 1994 Studies on the importance of microsomal epoxide hydrolase in the detoxification of arene oxides using the heterologous expression of the enzyme in mammalian cells. arene 83-88 epoxide hydrolase 1 Homo sapiens 29-57 8199297-2 1994 The catalytic mechanism of HAD and MEH have been recently shown to involve an ester intermediate formed by alkylation of an active site carboxyl group. Esters 78-83 epoxide hydrolase 1 Homo sapiens 35-38 8222491-4 1993 A mixed competitive and noncompetitive mechanism of inhibition best described the effect of progabide on microsomal epoxide hydrolase; the most potent inhibition was competitive. progabide 92-101 epoxide hydrolase 1 Homo sapiens 105-133 8453849-9 1993 We conclude that distribution of microsomal epoxide hydrolase activity in a study group can be measured pharmacokinetically by use of carbamazepine epoxide. carbamazepine epoxide 134-155 epoxide hydrolase 1 Homo sapiens 33-61 8222491-0 1993 In vivo and in vitro correlation of microsomal epoxide hydrolase inhibition by progabide. progabide 79-88 epoxide hydrolase 1 Homo sapiens 36-64 8222491-1 1993 Progabide was investigated as a potential inhibitor of microsomal epoxide hydrolase as a result of reports of elevated levels of carbamazepine-10,11-epoxide after coadministration of progabide and carbamazepine to patients with epilepsy. progabide 0-9 epoxide hydrolase 1 Homo sapiens 55-83 8222491-3 1993 Therapeutic concentrations of progabide inhibited S (+)-styrene oxide hydrolysis in human liver microsomes (inhibition constant [Ki] = 1.9 mumol/L) and purified human liver microsomal epoxide hydrolase (Ki = 4.4 mumol/L). progabide 30-39 epoxide hydrolase 1 Homo sapiens 173-201 8376374-0 1993 Bile acid transport into hepatocyte smooth endoplasmic reticulum vesicles is mediated by microsomal epoxide hydrolase, a membrane protein exhibiting two distinct topological orientations. Bile Acids and Salts 0-9 epoxide hydrolase 1 Homo sapiens 89-117 8376374-3 1993 The observed transport is mediated by the bifunctional protein, microsomal epoxide hydrolase (mEH) which can also mediate bile acid transport into hepatocytes across the sinusoidal plasma membrane (von Dippe, P., Amoui, M., Alves, C., and Levy, D. (1993) Am. Bile Acids and Salts 122-131 epoxide hydrolase 1 Homo sapiens 64-92 8460705-0 1993 Na(+)-dependent bile acid transport by hepatocytes is mediated by a protein similar to microsomal epoxide hydrolase. Bile Acids and Salts 16-25 epoxide hydrolase 1 Homo sapiens 87-115 1683079-5 1991 Recent work elucidating differences in isoenzyme forms of cytochrome P-450 enzyme systems, glutathione, and microsomal epoxide hydrolase has provided increased interest in the multiple individual pharmacogenetic differences that may be significant factors affecting increased susceptibility to birth defects in individuals and families with fetal exposure to phenytoin. Phenytoin 359-368 epoxide hydrolase 1 Homo sapiens 108-136 1793807-2 1991 cDNAs encoding CYP1A2, CYP2A6, and microsomal epoxide hydrolase (mEH) were introduced by using a vector conferring hygromycin B resistance, and cDNAs encoding CYP2E1 and CYP3A4 were introduced by using a vector conferring resistance to 1-histidinol. Hygromycin B 115-127 epoxide hydrolase 1 Homo sapiens 35-63 1575766-6 1992 Neither compound affected the formation of CBZ-10,11-E. Microsomal epoxide hydrolase (mEH), but not cytosolic epoxide hydrolase, caused a concentration-dependent inhibition of cytotoxicity reaching a maximum of 60% at 100 U of mEH. cbz-10 43-49 epoxide hydrolase 1 Homo sapiens 56-84 1540232-0 1992 Interaction of valproic acid and some analogues with microsomal epoxide hydrolase. Valproic Acid 15-28 epoxide hydrolase 1 Homo sapiens 53-81 2343725-4 1990 The urinary excretion of urea nitrogen and 3-methylhistidine (3-MeH), an indicator of muscle protein breakdown, increased significantly in both groups after surgery, by the same amount (P less than 0.05). 3-methylhistidine 43-60 epoxide hydrolase 1 Homo sapiens 64-67 1976080-0 1990 Unsubstituted amides: new class of potent inhibitors of human microsomal epoxide hydrolase. Amides 14-20 epoxide hydrolase 1 Homo sapiens 62-90 33794079-14 2021 CONCLUSIONS: It was concluded that in Hist139Arg of EPHX gene, fast genotype (Arg-Arg) was associated with impaired ventilatory functions. Arginine 45-48 epoxide hydrolase 1 Homo sapiens 52-56 33794079-9 2021 RESULTS: Significant reduction in forced vital capacity (FVC%) and forced expiratory volume in the first second (FEV1) levels in Tyr-Tyr and Tyr-Hist genotypes of EPHX (exon 3) was observed. tyrosyltyrosine 129-136 epoxide hydrolase 1 Homo sapiens 163-167 33794079-14 2021 CONCLUSIONS: It was concluded that in Hist139Arg of EPHX gene, fast genotype (Arg-Arg) was associated with impaired ventilatory functions. Arginine 78-81 epoxide hydrolase 1 Homo sapiens 52-56 33794079-9 2021 RESULTS: Significant reduction in forced vital capacity (FVC%) and forced expiratory volume in the first second (FEV1) levels in Tyr-Tyr and Tyr-Hist genotypes of EPHX (exon 3) was observed. Tyrosine 129-132 epoxide hydrolase 1 Homo sapiens 163-167 33769964-4 2021 In this research, four devices, including ZnO nanorod (nanotube)/MEH-PPV (CH3NH3PbI3) LEDs are simulated by SILVACO TCAD software. ch3nh3pbi3 74-84 epoxide hydrolase 1 Homo sapiens 65-68 34411648-0 2021 ABCB1 c.3435C>T and EPHX1 c.416A>G polymorphisms influence plasma carbamazepine concentration, metabolism, and pharmacoresistance in epileptic patients. Carbamazepine 66-79 epoxide hydrolase 1 Homo sapiens 20-25 34411648-1 2021 The gene polymorphisms of ABCB1, EPHX1, and SCN1A were found to influence carbamazepine (CBZ) metabolism and resistance in epilepsy patients, but the relevance remains controversial. Carbamazepine 74-87 epoxide hydrolase 1 Homo sapiens 33-38 34411648-1 2021 The gene polymorphisms of ABCB1, EPHX1, and SCN1A were found to influence carbamazepine (CBZ) metabolism and resistance in epilepsy patients, but the relevance remains controversial. Carbamazepine 89-92 epoxide hydrolase 1 Homo sapiens 33-38 34411648-2 2021 To reveal the relationships among the gene polymorphisms of ABCB1, EPHX1, SCN1A and the metabolism and resistance of CBZ, the databases of PubMed, EMBASE, Cochrane Library, Chinese National Knowledge Infrastructure, Chinese Science and Technique Journals, China Biology medicine disc and Wan Fang were retrieved for suitable studies up to April 2021. Carbamazepine 117-120 epoxide hydrolase 1 Homo sapiens 67-72 34411648-6 2021 Therefore, CBZ metabolism and resistance inpatientswithepilepsy may be adjusted by the gene polymorphisms of ABCB1 c.3435C>T and EPHX1 c.416A>G which provides the further scientific basis for clinical individualized therapy of epilepsy. Carbamazepine 11-14 epoxide hydrolase 1 Homo sapiens 129-134 34832783-4 2021 Forster resonance energy transfer (FRET) is more efficient in the binary hybrid of PFO/MDMO-PPV-DMP than in the PFO/MEH-PPV. perfluorooctane sulfonic acid 112-115 epoxide hydrolase 1 Homo sapiens 116-119 34672683-2 2021 The relationship between EPHX1 polymorphisms (Tyr113His and His139Arg) and overall survival (OS) and lung cancer (LC) risk was investigated. tyr113his 46-55 epoxide hydrolase 1 Homo sapiens 25-30 34832783-3 2021 The conjugation length of the PFO was tuned upon addition of acceptors (MEH-PPV or MDMO-PPV-DMP), as proved from shifting the emission and absorption peaks of the binary hybrids toward the acceptor in addition to enhancing the acceptor emission and reducing the absorbance of the PFO. perfluorooctane sulfonic acid 30-33 epoxide hydrolase 1 Homo sapiens 72-75 34708845-0 2021 Correction: Role of defective states in MgO nanoparticles on the photophysical properties and photostability of MEH-PPV/MgO nanocomposite. mgo 40-43 epoxide hydrolase 1 Homo sapiens 112-115 34708845-0 2021 Correction: Role of defective states in MgO nanoparticles on the photophysical properties and photostability of MEH-PPV/MgO nanocomposite. mgo 120-123 epoxide hydrolase 1 Homo sapiens 112-115 34832783-6 2021 Moreover, the tuning of the emission color can be attributed to the cascade of energy transfer from PFO to MEH-PPV, and then to MDMO-PPV-DMP. perfluorooctane sulfonic acid 100-103 epoxide hydrolase 1 Homo sapiens 107-110 34832783-3 2021 The conjugation length of the PFO was tuned upon addition of acceptors (MEH-PPV or MDMO-PPV-DMP), as proved from shifting the emission and absorption peaks of the binary hybrids toward the acceptor in addition to enhancing the acceptor emission and reducing the absorbance of the PFO. perfluorooctane sulfonic acid 280-283 epoxide hydrolase 1 Homo sapiens 72-75 34832783-6 2021 Moreover, the tuning of the emission color can be attributed to the cascade of energy transfer from PFO to MEH-PPV, and then to MDMO-PPV-DMP. mdmo-ppv-dmp 128-140 epoxide hydrolase 1 Homo sapiens 107-110 34769030-6 2021 The distinct metabolism of peptide epoxyketones, which is primarily mediated by microsomal epoxide hydrolase, is highlighted and postulated as a favorable property for the development of this class of compound in chronic conditions. epoxyketones 35-47 epoxide hydrolase 1 Homo sapiens 80-108 34234005-7 2021 Further study in intact hepatocytes and a hepatocellular carcinoma cell line revealed that KZR-616 metabolism was sensitive to an inhibitor of microsomal epoxide hydrolase (mEH) but not inhibitors of cytochrome P450 (CYP) or soluble epoxide hydrolase (sEH). kzr- 91-95 epoxide hydrolase 1 Homo sapiens 143-171 34599257-2 2021 The photochemical upconversion performance of these polymers as emitters are investigated using a palladium tetraphenyltetrabenzoporphyrin triplet sensitizer and MEH-PPV as reference. Polymers 52-60 epoxide hydrolase 1 Homo sapiens 162-165 34610057-0 2021 Role of defective states in MgO nanoparticles on the photophysical properties and photostability of MEH-PPV/MgO nanocomposite. mgo 28-31 epoxide hydrolase 1 Homo sapiens 100-103 34610057-0 2021 Role of defective states in MgO nanoparticles on the photophysical properties and photostability of MEH-PPV/MgO nanocomposite. mgo 108-111 epoxide hydrolase 1 Homo sapiens 100-103 34610057-3 2021 This article presents a detailed investigation on the influence of defective electronic states of MgO nanoparticles on the photophysical properties and photostability of a conjugated polymer, poly(2-methoxy-5-(2-ethylhyxyloxy)-1,4-phenylene vinylene) (MEH-PPV). Polymers 183-190 epoxide hydrolase 1 Homo sapiens 252-255 34610057-3 2021 This article presents a detailed investigation on the influence of defective electronic states of MgO nanoparticles on the photophysical properties and photostability of a conjugated polymer, poly(2-methoxy-5-(2-ethylhyxyloxy)-1,4-phenylene vinylene) (MEH-PPV). poly(2-methoxy-5-(2-ethylhyxyloxy)-1,4-phenylene vinylene) 192-250 epoxide hydrolase 1 Homo sapiens 252-255 34610057-6 2021 The nanocomposites demonstrated photoluminescence (PL) quenching owing to the transfer of electrons from MEH-PPV to the defective energy levels (oxygen vacancies) of MgO. Oxygen 145-151 epoxide hydrolase 1 Homo sapiens 105-108 34610057-6 2021 The nanocomposites demonstrated photoluminescence (PL) quenching owing to the transfer of electrons from MEH-PPV to the defective energy levels (oxygen vacancies) of MgO. mgo 166-169 epoxide hydrolase 1 Homo sapiens 105-108 34610057-8 2021 The MEH-PPV/MgO nanocomposite displayed 23% PL quantum efficiency. mgo 12-15 epoxide hydrolase 1 Homo sapiens 4-7 34610057-8 2021 The MEH-PPV/MgO nanocomposite displayed 23% PL quantum efficiency. pl 44-46 epoxide hydrolase 1 Homo sapiens 4-7 34610057-10 2021 Hence, this work validates the role of oxygen vacancies of MgO nanoparticles in the PL quenching and photostability enhancement of MEH-PPV. Oxygen 39-45 epoxide hydrolase 1 Homo sapiens 131-134 34610057-10 2021 Hence, this work validates the role of oxygen vacancies of MgO nanoparticles in the PL quenching and photostability enhancement of MEH-PPV. mgo 59-62 epoxide hydrolase 1 Homo sapiens 131-134 34612084-6 2021 CBZ daily dose was also influenced by NR1I2-rs3814055 and EPHX1-rs1051740. Carbamazepine 0-3 epoxide hydrolase 1 Homo sapiens 58-63 34612084-7 2021 Conclusion: Interindividual variability in CBZ treatment was partly explained by NR1I2, EPHX1 and SCN1A variants, as well as antiepileptic cotreatment in MM with epilepsy. Carbamazepine 43-46 epoxide hydrolase 1 Homo sapiens 88-93 34415151-3 2021 In this context, we have investigated the conformational disorder effect on the real-time photobleaching kinetics of a poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene) (MEH-PPV)/chloroform solution under deep-blue radiation. poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene) 119-176 epoxide hydrolase 1 Homo sapiens 178-181 34415151-3 2021 In this context, we have investigated the conformational disorder effect on the real-time photobleaching kinetics of a poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene) (MEH-PPV)/chloroform solution under deep-blue radiation. Chloroform 187-197 epoxide hydrolase 1 Homo sapiens 178-181 34415151-7 2021 Consequently, the effective conjugation length of MEH-PPV in chloroform decreases from nine to three coplanar repetitive units after 1 h of excitation, producing a drastic drop in photoluminescence. Chloroform 61-71 epoxide hydrolase 1 Homo sapiens 50-53 34342583-0 2021 EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence. Epoxy Compounds 71-78 epoxide hydrolase 1 Homo sapiens 0-5 34373022-0 2021 Association of EPHX1 polymorphisms with plasma concentration of carbamazepine in epileptic patients: Systematic review and meta-analysis. Carbamazepine 64-77 epoxide hydrolase 1 Homo sapiens 15-20 34373022-2 2021 Increasing evidence suggested that polymorphisms in Epoxide Hydrolase1 (EPHX1) gene are associated with the pharmacokinetics (PK) and pharmacodynamics (PD) of CBZ, albeit the results were inconsistent. Carbamazepine 159-162 epoxide hydrolase 1 Homo sapiens 52-70 34373022-2 2021 Increasing evidence suggested that polymorphisms in Epoxide Hydrolase1 (EPHX1) gene are associated with the pharmacokinetics (PK) and pharmacodynamics (PD) of CBZ, albeit the results were inconsistent. Carbamazepine 159-162 epoxide hydrolase 1 Homo sapiens 72-77 34373022-8 2021 A significant correlation was detected between EPHX1 rs1051740 T > C polymorphisms and decreased plasma concentration of CBZ (TT vs CC: SMD = 0.34, P < 0.001; TC vs CC: SMD = 0.35, P = 0.009). Carbamazepine 121-124 epoxide hydrolase 1 Homo sapiens 47-52 34373022-8 2021 A significant correlation was detected between EPHX1 rs1051740 T > C polymorphisms and decreased plasma concentration of CBZ (TT vs CC: SMD = 0.34, P < 0.001; TC vs CC: SMD = 0.35, P = 0.009). Technetium 159-161 epoxide hydrolase 1 Homo sapiens 47-52 34373022-11 2021 CONCLUSION: EPHX1 rs1051740 T > C and rs2234922 A > G are important genetic variants associated with plasma CBZ concentration. Carbamazepine 108-111 epoxide hydrolase 1 Homo sapiens 12-17 34373022-12 2021 The role of EPHX1 polymorphisms in the interindividual variability of plasma CBZ concentration varied significantly among different ethnic groups, which should be considered during clinical validation and in future studies. Carbamazepine 77-80 epoxide hydrolase 1 Homo sapiens 12-17 34360828-1 2021 The environmental pollutant benzo(a)pyrene (BaP) is a human carcinogen that reacts with DNA after metabolic activation catalysed by cytochromes P450 (CYP) 1A1 and 1B1 together with microsomal epoxide hydrolase. Benzo(a)pyrene 28-42 epoxide hydrolase 1 Homo sapiens 181-209 34360828-1 2021 The environmental pollutant benzo(a)pyrene (BaP) is a human carcinogen that reacts with DNA after metabolic activation catalysed by cytochromes P450 (CYP) 1A1 and 1B1 together with microsomal epoxide hydrolase. Benzo(a)pyrene 44-47 epoxide hydrolase 1 Homo sapiens 181-209 34266094-0 2021 Lasing from MEH-PPV with a refractive index tunable by electron irradiation. lasing 0-6 epoxide hydrolase 1 Homo sapiens 12-15 35506539-4 2022 All of the polymers when highly diluted (c = 0.1 wt %) exhibited massive eta increases after stretching to very large strains (~300-500%) via micronecking, with the rigid polyfluorene (PFO) and semirigid MEH-PPV both manifesting eta 90%, while the most flexible yet regioregular polythiophene (P3HT-rr) exhibited a 10-fold increase to ~21%. Polymers 11-19 epoxide hydrolase 1 Homo sapiens 204-207 34066758-5 2021 Recent findings suggest that other epoxide hydrolases (EHs) such as microsomal epoxide hydrolase (mEH) and epoxide hydrolase-3 (EH3) can contribute significantly to the in vivo metabolism of EpFAs. epfas 191-196 epoxide hydrolase 1 Homo sapiens 68-96 35445643-2 2022 Thus, in the present study, we have comprehensively investigated the associations between SNPs of the Phase II detoxifying genes and its relationship towards platinum-induced toxicity of lung cancer patients.A total of 273 samples were enrolled in this study and polymorphisms of gene NQO1 (609C > T), SULT1A1 (Arg213 His), EPHX1 (Tyr113His, His139Arg), and NAT2 (481C > T, 803A > G, 590 G > A, 857 G > A) were evaluated in our study for their associated adverse events caused due to the administration of platinum-based chemotherapy to the lung cancer patients.For NQO1 609C > T polymorphism, the TT genotype showed reduced risk of constipation (OR =0.10, p=0.04) and anorexia (OR =0.15, p=0.03). Platinum 158-166 epoxide hydrolase 1 Homo sapiens 324-329 35243864-1 2022 An environmentally friendly and highly diastereoselective method for synthesizing indanes has been developed via a metastable-state photoacid system containing catalytic protonated merocyanine (MEH). indan 82-89 epoxide hydrolase 1 Homo sapiens 194-197 35243864-1 2022 An environmentally friendly and highly diastereoselective method for synthesizing indanes has been developed via a metastable-state photoacid system containing catalytic protonated merocyanine (MEH). merocyanine 181-192 epoxide hydrolase 1 Homo sapiens 194-197 35243864-2 2022 Under visible-light irradiation, MEH yields a metastable spiro structure and liberated protons, which facilitates the formation of carbocations from benzyl alcohols, thus delivering diverse molecules in the presence of various nucleophiles. Benzyl Alcohols 149-164 epoxide hydrolase 1 Homo sapiens 33-36 35160502-1 2022 A new copolymer has been studied, which is formed by Poly(2-methoxy-5-(2-ethyl-hexyloxy)-1,4-phenylene-vinylene) (MEH-PPV) and poly(3-hexylthiophene) (P3HT). copolymer 6-15 epoxide hydrolase 1 Homo sapiens 114-117 35160502-1 2022 A new copolymer has been studied, which is formed by Poly(2-methoxy-5-(2-ethyl-hexyloxy)-1,4-phenylene-vinylene) (MEH-PPV) and poly(3-hexylthiophene) (P3HT). poly(2-methoxy-5-(2-ethyl-hexyloxy)-1,4-phenylene-vinylene) 53-112 epoxide hydrolase 1 Homo sapiens 114-117 35160502-1 2022 A new copolymer has been studied, which is formed by Poly(2-methoxy-5-(2-ethyl-hexyloxy)-1,4-phenylene-vinylene) (MEH-PPV) and poly(3-hexylthiophene) (P3HT). poly(3-hexylthiophene) 151-155 epoxide hydrolase 1 Homo sapiens 114-117 2803885-6 1989 Urinary excretion of urea nitrogen and 3-methylhistidine (3-MeH) after surgery was significantly lower in the warmed group compared with the cold group (P less than 0.05). 3-methylhistidine 39-56 epoxide hydrolase 1 Homo sapiens 60-63 2501059-0 1989 Inhibition of human liver microsomal epoxide hydrolase by valproate and valpromide: in vitro/in vivo correlation. Valproic Acid 58-67 epoxide hydrolase 1 Homo sapiens 26-54 2501059-0 1989 Inhibition of human liver microsomal epoxide hydrolase by valproate and valpromide: in vitro/in vivo correlation. dipropylacetamide 72-82 epoxide hydrolase 1 Homo sapiens 26-54 2501059-2 1989 In this study, therapeutic concentrations of valproic acid (less than 1 mmol/L) and valpromide (less than 10 mumol/L) inhibited hydrolysis of carbamazepine epoxide and styrene oxide in human liver microsomes and in preparations of purified human liver microsomal epoxide hydrolase. Valproic Acid 45-58 epoxide hydrolase 1 Homo sapiens 252-280 2501059-2 1989 In this study, therapeutic concentrations of valproic acid (less than 1 mmol/L) and valpromide (less than 10 mumol/L) inhibited hydrolysis of carbamazepine epoxide and styrene oxide in human liver microsomes and in preparations of purified human liver microsomal epoxide hydrolase. dipropylacetamide 84-94 epoxide hydrolase 1 Homo sapiens 252-280 2501059-2 1989 In this study, therapeutic concentrations of valproic acid (less than 1 mmol/L) and valpromide (less than 10 mumol/L) inhibited hydrolysis of carbamazepine epoxide and styrene oxide in human liver microsomes and in preparations of purified human liver microsomal epoxide hydrolase. carbamazepine epoxide 142-163 epoxide hydrolase 1 Homo sapiens 252-280 2501059-2 1989 In this study, therapeutic concentrations of valproic acid (less than 1 mmol/L) and valpromide (less than 10 mumol/L) inhibited hydrolysis of carbamazepine epoxide and styrene oxide in human liver microsomes and in preparations of purified human liver microsomal epoxide hydrolase. styrene oxide 168-181 epoxide hydrolase 1 Homo sapiens 252-280 2501059-6 1989 Valproic acid and valpromide are the first drugs known to inhibit microsomal epoxide hydrolase, an important detoxification enzyme, at therapeutic concentrations. Valproic Acid 0-13 epoxide hydrolase 1 Homo sapiens 66-94 2501059-6 1989 Valproic acid and valpromide are the first drugs known to inhibit microsomal epoxide hydrolase, an important detoxification enzyme, at therapeutic concentrations. dipropylacetamide 18-28 epoxide hydrolase 1 Homo sapiens 66-94 3780165-3 1986 During mouth breathing, temperatures are significantly higher (TI = 28.1 degrees C, TE = 31.5 degrees C) and the amount of expired water larger (MEH2O = 27.8 mg dm-3 BTPS) than during nose breathing (TI = 24.8 degrees C; TE = 29.6 degrees C; MEH2O = 26.6 mg dm-3 BTPS). Water 131-136 epoxide hydrolase 1 Homo sapiens 145-148 2634095-5 1989 4OH-DPT inhibits, but 5OH-DPT enhances, microsomal epoxide hydrolase activity. 4oh-dpt 0-7 epoxide hydrolase 1 Homo sapiens 40-68 2634095-5 1989 4OH-DPT inhibits, but 5OH-DPT enhances, microsomal epoxide hydrolase activity. 5oh-dpt 22-29 epoxide hydrolase 1 Homo sapiens 40-68 2634095-8 1989 Microsomal epoxide hydrolase activity is enhanced by 2-aminothiazole and levamisole in vitro. 2-aminothiazole 53-68 epoxide hydrolase 1 Homo sapiens 0-28 2634095-8 1989 Microsomal epoxide hydrolase activity is enhanced by 2-aminothiazole and levamisole in vitro. Levamisole 73-83 epoxide hydrolase 1 Homo sapiens 0-28 2729567-0 1989 Simultaneous determination of cytosolic glutathione S-transferase and microsomal epoxide hydrolase activity toward benzo[a]pyrene-4,5-oxide by high-performance liquid chromatography. benzo(a)pyrene 4,5-epoxide 115-139 epoxide hydrolase 1 Homo sapiens 70-98 2729567-1 1989 Cytosolic glutathione S-transferase (GST) and microsomal epoxide hydrolase (EH) are important detoxification enzymes for many epoxide xenobiotics. epoxide xenobiotics 126-145 epoxide hydrolase 1 Homo sapiens 46-74 6275561-1 1981 Control SV40-transformed human fibroblasts can be readily adapted to growth on medium containing galactose as sole hexose source (galactose-MEH). Galactose 97-106 epoxide hydrolase 1 Homo sapiens 140-143 6811857-2 1982 Human liver microsomal epoxide hydrolase was purified to apparent homogeneity as judged by a single protein-staining band in sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Sodium Dodecyl Sulfate 125-147 epoxide hydrolase 1 Homo sapiens 12-40 6811857-2 1982 Human liver microsomal epoxide hydrolase was purified to apparent homogeneity as judged by a single protein-staining band in sodium dodecyl sulfate-polyacrylamide gel electrophoresis. polyacrylamide 148-162 epoxide hydrolase 1 Homo sapiens 12-40 6275561-1 1981 Control SV40-transformed human fibroblasts can be readily adapted to growth on medium containing galactose as sole hexose source (galactose-MEH). Galactose 130-139 epoxide hydrolase 1 Homo sapiens 140-143 7311737-2 1981 Analysis of microsomal epoxide hydrolase and phospholipase A2 activity against a phospholipid epoxide commonly encountered in tissues indicated it to be a poor substrate for epoxide hydrolase, but rapidly hydrolyzed by phospholipase A2. phospholipid epoxide 81-101 epoxide hydrolase 1 Homo sapiens 12-40 6790901-1 1981 The urinary excretion of 3-methylhistidine (3 MEH) has been shown to be a reliable index of muscle protein breakdown. 3-methylhistidine 25-42 epoxide hydrolase 1 Homo sapiens 46-49 6790901-12 1981 This was reflected in the 3 MEH to creatinine molar ratio increase from 0.018 for controls to 0.030-0.040 in sepsis and trauma. Creatinine 35-45 epoxide hydrolase 1 Homo sapiens 28-31 7226277-6 1981 Cyclohexene oxide and 1,2-epoxy-3,3,3-trichloropropane, two well known inhibitors of the microsomal epoxide hydrolase(s) caused a marked inhibition, metyrapone had a strong activating effect whereas SKF-525A had no effect. cyclohexene oxide 0-17 epoxide hydrolase 1 Homo sapiens 89-117 7226277-6 1981 Cyclohexene oxide and 1,2-epoxy-3,3,3-trichloropropane, two well known inhibitors of the microsomal epoxide hydrolase(s) caused a marked inhibition, metyrapone had a strong activating effect whereas SKF-525A had no effect. Trichloroepoxypropane 22-54 epoxide hydrolase 1 Homo sapiens 89-117 7226277-6 1981 Cyclohexene oxide and 1,2-epoxy-3,3,3-trichloropropane, two well known inhibitors of the microsomal epoxide hydrolase(s) caused a marked inhibition, metyrapone had a strong activating effect whereas SKF-525A had no effect. Metyrapone 149-159 epoxide hydrolase 1 Homo sapiens 89-117 7226277-6 1981 Cyclohexene oxide and 1,2-epoxy-3,3,3-trichloropropane, two well known inhibitors of the microsomal epoxide hydrolase(s) caused a marked inhibition, metyrapone had a strong activating effect whereas SKF-525A had no effect. Proadifen 199-207 epoxide hydrolase 1 Homo sapiens 89-117 5082499-0 1972 Stereoselective hydrolysis of acyclic olefin oxide to glycols by hepatic microsomal epoxide hydrolase. acyclic olefin oxide 30-50 epoxide hydrolase 1 Homo sapiens 73-101 7228854-0 1981 Enantioselectivity of microsomal epoxide hydrolase toward arene oxide substrates. Benzene oxide 58-69 epoxide hydrolase 1 Homo sapiens 22-50 7228854-1 1981 The enantioselectivity of native and purified hepatic microsomal epoxide hydrolase toward one symmetrical arene oxide, phenanthrene 9,10-oxide, and the resolved enantiomers of the three chiral arene oxide substrates, benzo[a]pyrene 4,5- and 7,8-oxide and benzo[a]anthracene 5,6-oxide was examined. Benzene oxide 106-117 epoxide hydrolase 1 Homo sapiens 54-82 7228854-1 1981 The enantioselectivity of native and purified hepatic microsomal epoxide hydrolase toward one symmetrical arene oxide, phenanthrene 9,10-oxide, and the resolved enantiomers of the three chiral arene oxide substrates, benzo[a]pyrene 4,5- and 7,8-oxide and benzo[a]anthracene 5,6-oxide was examined. 9,10-epoxy-9,10-dihydrophenanthrene 119-142 epoxide hydrolase 1 Homo sapiens 54-82 7228854-1 1981 The enantioselectivity of native and purified hepatic microsomal epoxide hydrolase toward one symmetrical arene oxide, phenanthrene 9,10-oxide, and the resolved enantiomers of the three chiral arene oxide substrates, benzo[a]pyrene 4,5- and 7,8-oxide and benzo[a]anthracene 5,6-oxide was examined. Benzene oxide 193-204 epoxide hydrolase 1 Homo sapiens 54-82 7228854-1 1981 The enantioselectivity of native and purified hepatic microsomal epoxide hydrolase toward one symmetrical arene oxide, phenanthrene 9,10-oxide, and the resolved enantiomers of the three chiral arene oxide substrates, benzo[a]pyrene 4,5- and 7,8-oxide and benzo[a]anthracene 5,6-oxide was examined. benzo[a]pyrene 4,5- and 7,8-oxide 217-250 epoxide hydrolase 1 Homo sapiens 54-82 7228854-1 1981 The enantioselectivity of native and purified hepatic microsomal epoxide hydrolase toward one symmetrical arene oxide, phenanthrene 9,10-oxide, and the resolved enantiomers of the three chiral arene oxide substrates, benzo[a]pyrene 4,5- and 7,8-oxide and benzo[a]anthracene 5,6-oxide was examined. 1a,11b-dihydrotetrapheno[5,6-b]oxirene 255-283 epoxide hydrolase 1 Homo sapiens 54-82 6990840-1 1980 Microsomal epoxide hydrolase (EC 3.3.2.3. ; formerly EC 4.2.1.63) catalyse the hydration of epoxides into trans dihydro-diols, easily excretable hydrophil compounds. Epoxy Compounds 92-100 epoxide hydrolase 1 Homo sapiens 0-28 6990840-1 1980 Microsomal epoxide hydrolase (EC 3.3.2.3. ; formerly EC 4.2.1.63) catalyse the hydration of epoxides into trans dihydro-diols, easily excretable hydrophil compounds. trans dihydro-diols 106-125 epoxide hydrolase 1 Homo sapiens 0-28 508716-2 1979 The amount of 3-methylhistidine (3-MeH) has been measured in eighty-eight samples of tissue taken post-mortem from five adults. 3-methylhistidine 14-31 epoxide hydrolase 1 Homo sapiens 35-38 888785-1 1977 Muscle protein catabolism has been evaluated using the excretion of urinary 3-methylhistidine (3-MEH) is six normal male and six normal female subjects and in four surgical patients, two of whom developed febrile episodes during the course of their study. 3-methylhistidine 76-93 epoxide hydrolase 1 Homo sapiens 97-100 7344487-0 1981 Benzil, a selective inducer and a potent in vitro activator of microsomal epoxide hydrolase. benzil 0-6 epoxide hydrolase 1 Homo sapiens 63-91 4452209-0 1974 Enzymatic hydrolysis of mono-n-alkyl substituted ethylene oxides and their inhibitory effects on hepatic microsomal epoxide hydrolase. mono-n-alkyl substituted ethylene oxides 24-64 epoxide hydrolase 1 Homo sapiens 105-133 5082499-0 1972 Stereoselective hydrolysis of acyclic olefin oxide to glycols by hepatic microsomal epoxide hydrolase. Glycols 54-61 epoxide hydrolase 1 Homo sapiens 73-101 33217013-11 2021 EPHX1-416G/G genotype was a significant covariate for the clearance of carbamazepine 10,11-epoxide. Carbamazepine 71-84 epoxide hydrolase 1 Homo sapiens 0-5 5569111-0 1971 Stereoselective hydrolysis of 2,3-epoxysteroids by hepatic microsomal epoxide hydrolase. 2,3-epoxysteroids 30-47 epoxide hydrolase 1 Homo sapiens 59-87 5116510-0 1971 Stereoselective hydrolysis of cis- and trans-stilbene oxides by hepatic microsomal epoxide hydrolase. cis- and trans-stilbene oxides 30-60 epoxide hydrolase 1 Homo sapiens 72-100 33217013-11 2021 EPHX1-416G/G genotype was a significant covariate for the clearance of carbamazepine 10,11-epoxide. 10,11-epoxide 85-98 epoxide hydrolase 1 Homo sapiens 0-5 33217013-12 2021 CONCLUSION: Our data indicate that carbamazepine clearance was affected by total dose and phenytoin co-administration, but not by genetic factors, while carbamazepine 10,11-epoxide clearance was affected by a variant in the microsomal epoxide hydrolase gene. Carbamazepine 153-166 epoxide hydrolase 1 Homo sapiens 224-252 33217013-12 2021 CONCLUSION: Our data indicate that carbamazepine clearance was affected by total dose and phenytoin co-administration, but not by genetic factors, while carbamazepine 10,11-epoxide clearance was affected by a variant in the microsomal epoxide hydrolase gene. 10,11-epoxide 167-180 epoxide hydrolase 1 Homo sapiens 224-252 33670613-2 2021 The improved energy transfer from PFO to MEH-PPV upon an increment of the STNCs was achieved by examining absorbance, emission (PL) and photoluminescence excitation (PLE) spectra. perfluorooctane sulfonic acid 34-37 epoxide hydrolase 1 Homo sapiens 41-44 33958549-6 2021 Our results showed that 13 SNPs on 6 genes (CYP2C9, VKORC1, ABCB1, PROC, EPHX1 and SETD1A) were associated with the individual stable warfarin dose. Warfarin 134-142 epoxide hydrolase 1 Homo sapiens 73-78 33958549-9 2021 We discovered that, genetic variants in CYP2C9, VKORC1, ABCB1, PROC, EPHX1 and SETD1A may affect the stable warfarin dose requirement in Han Chinese patients with valvular disease. Warfarin 108-116 epoxide hydrolase 1 Homo sapiens 69-74 33923106-1 2021 We investigated the effects of molecular ordering on the electro-optical characteristics of organic light-emitting diodes (OLEDs) with an emission layer (EML) of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV). poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 162-219 epoxide hydrolase 1 Homo sapiens 221-224 33994786-1 2020 Purpose: Soluble epoxide hydrolase (sEH) and microsomal epoxide hydrolase (mEH) both catalyze the metabolism of epoxyeicosatrienoic acids (EETs), lipid signaling molecules that are protective against ischemic brain injury owing to their participation in the regulation of vascular tone and cerebral blood flow. epoxyeicosatrienoic acids 112-137 epoxide hydrolase 1 Homo sapiens 45-73 33994786-1 2020 Purpose: Soluble epoxide hydrolase (sEH) and microsomal epoxide hydrolase (mEH) both catalyze the metabolism of epoxyeicosatrienoic acids (EETs), lipid signaling molecules that are protective against ischemic brain injury owing to their participation in the regulation of vascular tone and cerebral blood flow. eets 139-143 epoxide hydrolase 1 Homo sapiens 45-73 33656311-2 2021 Hybrid films were prepared with a spin-coating method with the mixture solution containing tetraphenylethene (TPE)-integrated polyhedral oligomeric silsesquioxane (POSS) and poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV). tetraphenylethylene 91-108 epoxide hydrolase 1 Homo sapiens 235-238 33656311-2 2021 Hybrid films were prepared with a spin-coating method with the mixture solution containing tetraphenylethene (TPE)-integrated polyhedral oligomeric silsesquioxane (POSS) and poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV). 3'-o-acetylthymidine-(5' diphosphate phenyl ester) 110-113 epoxide hydrolase 1 Homo sapiens 235-238 33656311-7 2021 By modulating introduction ratios of TPE-POSS, dual-emission properties followed by white-light luminescence composed of cyan and orange emissions from TPE-POSS and MEH-PPV, respectively, were accomplished. 3'-o-acetylthymidine-(5' diphosphate phenyl ester) 37-40 epoxide hydrolase 1 Homo sapiens 165-168 33670613-3 2021 The shorter values of the quantum yield (phiDA) and lifetime (tauDA) of the PFO in the hybrid thin films compared with the pure PFO, indicating efficient energy transfer from PFO to MEH-PPV with the increment of STNCs in the hybrid. perfluorooctane sulfonic acid 76-79 epoxide hydrolase 1 Homo sapiens 182-185 33670613-3 2021 The shorter values of the quantum yield (phiDA) and lifetime (tauDA) of the PFO in the hybrid thin films compared with the pure PFO, indicating efficient energy transfer from PFO to MEH-PPV with the increment of STNCs in the hybrid. perfluorooctane sulfonic acid 128-131 epoxide hydrolase 1 Homo sapiens 182-185 33670613-3 2021 The shorter values of the quantum yield (phiDA) and lifetime (tauDA) of the PFO in the hybrid thin films compared with the pure PFO, indicating efficient energy transfer from PFO to MEH-PPV with the increment of STNCs in the hybrid. perfluorooctane sulfonic acid 128-131 epoxide hydrolase 1 Homo sapiens 182-185 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. poly(9,9-di-n-octyl-2,7-fluorene) 127-130 epoxide hydrolase 1 Homo sapiens 148-151 33618338-4 2021 In this research, four devices, including ZnO nanorod (nanotube)/ MEH-PPV (CH3NH3PbI3) LEDs, are simulated by SIVACO TCAD software. ch3nh3pbi3 75-85 epoxide hydrolase 1 Homo sapiens 66-69 33671323-6 2021 The carbamazepine-10,11-epoxide model applies metabolism by epoxide hydroxylase 1 (EPHX1) and glomerular filtration. Carbamazepine 4-17 epoxide hydrolase 1 Homo sapiens 60-81 33671323-6 2021 The carbamazepine-10,11-epoxide model applies metabolism by epoxide hydroxylase 1 (EPHX1) and glomerular filtration. Carbamazepine 4-17 epoxide hydrolase 1 Homo sapiens 83-88 33671323-6 2021 The carbamazepine-10,11-epoxide model applies metabolism by epoxide hydroxylase 1 (EPHX1) and glomerular filtration. 10,11-epoxide 18-31 epoxide hydrolase 1 Homo sapiens 60-81 33671323-6 2021 The carbamazepine-10,11-epoxide model applies metabolism by epoxide hydroxylase 1 (EPHX1) and glomerular filtration. 10,11-epoxide 18-31 epoxide hydrolase 1 Homo sapiens 83-88 33551540-1 2021 An Al/p-Si/poly[2-methoxy-5-(2-ethylhexoxy)-p-phenylenevinylene] (MEH-PPV)/Ag organic heterojunction has been prepared using homemade ultrasonic spray pyrolysis (USP) equipment for deposition of the organic thin film and physical vapor deposition (PVD) for the metallic contacts. Aluminum 3-5 epoxide hydrolase 1 Homo sapiens 66-69 33551540-1 2021 An Al/p-Si/poly[2-methoxy-5-(2-ethylhexoxy)-p-phenylenevinylene] (MEH-PPV)/Ag organic heterojunction has been prepared using homemade ultrasonic spray pyrolysis (USP) equipment for deposition of the organic thin film and physical vapor deposition (PVD) for the metallic contacts. poly[2-methoxy-5-(2-ethylhexoxy)-p-phenylenevinylene] 11-64 epoxide hydrolase 1 Homo sapiens 66-69 33551540-4 2021 The amorphous nature of the MEH-PPV polymer was confirmed by its x-ray diffraction pattern. Polymers 36-43 epoxide hydrolase 1 Homo sapiens 28-31 33105689-1 2020 The triplet energy transfer mechanism of novel poly(9,9-di-n-octylflourenyl-2,7-diyl) (PFO)/poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV)/CsPbBr3 perovskite quantum dot (PQD) hybrid thin films was comprehensively investigated. poly(9,9-di-n-octylflourenyl-2,7-diyl) 47-85 epoxide hydrolase 1 Homo sapiens 151-154 33105689-1 2020 The triplet energy transfer mechanism of novel poly(9,9-di-n-octylflourenyl-2,7-diyl) (PFO)/poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV)/CsPbBr3 perovskite quantum dot (PQD) hybrid thin films was comprehensively investigated. poly(9,9-di-n-octyl-2,7-fluorene) 87-90 epoxide hydrolase 1 Homo sapiens 151-154 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. 1,4-benzoquinone dioxime 139-143 epoxide hydrolase 1 Homo sapiens 80-83 33105689-1 2020 The triplet energy transfer mechanism of novel poly(9,9-di-n-octylflourenyl-2,7-diyl) (PFO)/poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV)/CsPbBr3 perovskite quantum dot (PQD) hybrid thin films was comprehensively investigated. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 92-149 epoxide hydrolase 1 Homo sapiens 151-154 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. poly(9,9-di-n-octyl-2,7-fluorene) 76-79 epoxide hydrolase 1 Homo sapiens 80-83 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. poly(9,9-di-n-octyl-2,7-fluorene) 76-79 epoxide hydrolase 1 Homo sapiens 148-151 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. poly(9,9-di-n-octyl-2,7-fluorene) 76-79 epoxide hydrolase 1 Homo sapiens 148-151 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. DOP protocol 84-87 epoxide hydrolase 1 Homo sapiens 80-83 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. DOP protocol 84-87 epoxide hydrolase 1 Homo sapiens 148-151 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. DOP protocol 84-87 epoxide hydrolase 1 Homo sapiens 148-151 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. 1,4-benzoquinone dioxime 88-92 epoxide hydrolase 1 Homo sapiens 80-83 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. 1,4-benzoquinone dioxime 88-92 epoxide hydrolase 1 Homo sapiens 148-151 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. 1,4-benzoquinone dioxime 88-92 epoxide hydrolase 1 Homo sapiens 148-151 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. poly(9,9-di-n-octyl-2,7-fluorene) 127-130 epoxide hydrolase 1 Homo sapiens 80-83 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. 1,4-benzoquinone dioxime 139-143 epoxide hydrolase 1 Homo sapiens 80-83 33105689-3 2020 The triplet non-radiative Forster resonance energy transfers (FRETs) in the PFO/MEH-PPV/PQDs ternary blend, the dual FRET from PFO to both PQDs and MEH-PPV, and the secondary FRET from PQDs to MEH-PPV were observed. poly(9,9-di-n-octyl-2,7-fluorene) 127-130 epoxide hydrolase 1 Homo sapiens 148-151 33105689-4 2020 The values of the Forster radius (Ro) of FRET from PFO to MEH-PPV in the presence of various PQD contents (Case I) increased from 92.3 to 104.7 A, and they decreased gradually from 68.0 to 39.5 A for FRET from PFO to PQDs in the presence of MEH-PPV (Case II). poly(9,9-di-n-octyl-2,7-fluorene) 51-54 epoxide hydrolase 1 Homo sapiens 58-61 33105689-4 2020 The values of the Forster radius (Ro) of FRET from PFO to MEH-PPV in the presence of various PQD contents (Case I) increased from 92.3 to 104.7 A, and they decreased gradually from 68.0 to 39.5 A for FRET from PFO to PQDs in the presence of MEH-PPV (Case II). poly(9,9-di-n-octyl-2,7-fluorene) 51-54 epoxide hydrolase 1 Homo sapiens 241-244 33105689-4 2020 The values of the Forster radius (Ro) of FRET from PFO to MEH-PPV in the presence of various PQD contents (Case I) increased from 92.3 to 104.7 A, and they decreased gradually from 68.0 to 39.5 A for FRET from PFO to PQDs in the presence of MEH-PPV (Case II). poly(9,9-di-n-octyl-2,7-fluorene) 210-213 epoxide hydrolase 1 Homo sapiens 58-61 33105689-8 2020 To prevent intermolecular transfer in PFO, the concentrations of MEH-PPV (Case I) and PQDs (Case II) should be decreased to a range of 0.57-0.39 mM and increased in the range of 1.42-7.25 mM. poly(9,9-di-n-octyl-2,7-fluorene) 38-41 epoxide hydrolase 1 Homo sapiens 65-68 32067389-0 2020 Proteomic Analysis Reveals That EPHX1 Contributes to 5-Fluorouracil Resistance in a Human Hepatocellular Carcinoma Cell Line. Fluorouracil 53-67 epoxide hydrolase 1 Homo sapiens 32-37 32559398-0 2020 Effects of EPHX1 rs2260863 polymorphisms on warfarin maintenance dose in very elderly, frail Han-Chinese population. Warfarin 44-52 epoxide hydrolase 1 Homo sapiens 11-16 32559398-4 2020 Results & conclusion: EPHX1 rs2260863 nonvariant CC homozygotes required significantly lower daily warfarin dose than GC heterozygotes. Warfarin 99-107 epoxide hydrolase 1 Homo sapiens 22-27 32525314-1 2020 IIn this paper, we report a simple procedure to decouple effects from temperature and volume on the emission properties of thin films of poly[2-methoxy-5-(2 -ethylhexyloxy)-1,4-phenylene-vinylene] (MEH-PPV). poly[2-methoxy-5-(2 -ethylhexyloxy)-1,4-phenylene-vinylene] 137-196 epoxide hydrolase 1 Homo sapiens 198-201 32525314-2 2020 This procedure consists in applying a positive pressure close to the beta-relaxation temperature, Tbeta (~220K), of MEH-PPV, which controls the molecular movement to retain a disordered state for the polymer chains even after the sample is cooled down to room temperature. tbeta 98-103 epoxide hydrolase 1 Homo sapiens 116-119 32967360-4 2020 Through efficient Forster Resonance Energy Transfer (FRET), the desired white emission was achieved with PFO/0.3 wt.% F8BT/0.5 wt.% MEH-PPV ternary blend thin film. poly(9,9-di-n-octyl-2,7-fluorene) 105-108 epoxide hydrolase 1 Homo sapiens 132-135 32784767-0 2020 Effect of Thermal Annealing on Conformation of MEH-PPV Chains in Polymer Matrix: Coexistence of H- and J-Aggregates. DOP protocol 51-54 epoxide hydrolase 1 Homo sapiens 47-50 32784767-0 2020 Effect of Thermal Annealing on Conformation of MEH-PPV Chains in Polymer Matrix: Coexistence of H- and J-Aggregates. Polymers 65-72 epoxide hydrolase 1 Homo sapiens 47-50 32784767-1 2020 In diluted solid solution using poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene) (MEH-PPV) and polymethyl methacrylate (PMMA) or polystyrene (PS), both aggregated and extended conformations could be formed according to the weight ratio. poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene) 32-89 epoxide hydrolase 1 Homo sapiens 91-94 32784767-2 2020 Aggregated conformation in as-cast MEH-PPV/PMMA film presented a J-aggregate-like photoluminescence (PL) emission. Polymethyl Methacrylate 43-47 epoxide hydrolase 1 Homo sapiens 35-38 32784767-5 2020 On the contrary, in MEH-PPV/PS blends, extended conformation dominated in as-cast film with oligomer-like emissions; after annealing at 160 C, both J- and H- aggregate-like PL emissions were observed, indicating the conformation transitioned from extended to aggregated. Polystyrenes 28-30 epoxide hydrolase 1 Homo sapiens 20-23 31893499-5 2020 Inspired by biomineralization, here, C60 single-crystals are prepared in organogel matrix of Poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenvinylene] (MEH-PPV) to form MEH-PPV:C60 composites. fullerene C60 37-40 epoxide hydrolase 1 Homo sapiens 151-154 31813306-0 2020 Re: Boeckstyns MEH, Merser S, Cool P. Reporting implant survival. Rhenium 0-2 epoxide hydrolase 1 Homo sapiens 15-18 31625392-8 2019 The photonic memory behavior was also observed in the blend electrets of PS with the low band gap polymer, MEH-PPV, SY-PPV, or F8BT, by changing the photoresponsive light sources. Polystyrenes 73-75 epoxide hydrolase 1 Homo sapiens 107-110 31808338-3 2020 A two-terminal diode with a configuration of indium tin oxide/2D CMP/hollow MEH-PPV/Al was fabricated by employing the prepared bilayer heterojunction. Aluminum 84-86 epoxide hydrolase 1 Homo sapiens 76-79 31893499-5 2020 Inspired by biomineralization, here, C60 single-crystals are prepared in organogel matrix of Poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenvinylene] (MEH-PPV) to form MEH-PPV:C60 composites. fullerene C60 37-40 epoxide hydrolase 1 Homo sapiens 168-171 31893499-6 2020 Essentially, networks of MEH-PPV are incorporated into growing C60 crystals and penetrate throughout the crystals, resulting in crystal/gel-network inter-penetrating composites. fullerene C60 63-66 epoxide hydrolase 1 Homo sapiens 25-28 31650507-0 2019 Association between EPHX1 polymorphisms and carbamazepine metabolism in epilepsy: a meta-analysis. Carbamazepine 44-57 epoxide hydrolase 1 Homo sapiens 20-25 31650507-2 2019 Aim of the review To obtain a more precise estimation of the associations between EPHX1 polymorphisms and carbamazepine metabolism and resistance. Carbamazepine 106-119 epoxide hydrolase 1 Homo sapiens 82-87 31650507-7 2019 EPHX1 rs1051740 polymorphism was significantly associated with adjusted concentrations of both carbamazepine (CC vs. TT: P = 0.02; CC vs. CT + TT: P = 0.005) and carbamazepine-10,11-epoxide (CC vs. CT + TT: P = 0.03). Carbamazepine 95-108 epoxide hydrolase 1 Homo sapiens 0-5 31650507-7 2019 EPHX1 rs1051740 polymorphism was significantly associated with adjusted concentrations of both carbamazepine (CC vs. TT: P = 0.02; CC vs. CT + TT: P = 0.005) and carbamazepine-10,11-epoxide (CC vs. CT + TT: P = 0.03). carbamazepine epoxide 162-189 epoxide hydrolase 1 Homo sapiens 0-5 31650507-8 2019 Furthermore, EPHX1 rs2234922 polymorphism was also observed to be significantly associated with decreased adjusted concentrations of carbamazepine-10,11-trans dihydrodiol (GG vs. GA + AA: P = 0.04) and CBZD:CBZE ratio (GG vs. AA: P = 0.008; GG vs. GA + AA: P = 0.0008). carbamazepine-10,11-dihydrodiol 133-170 epoxide hydrolase 1 Homo sapiens 13-18 31650507-8 2019 Furthermore, EPHX1 rs2234922 polymorphism was also observed to be significantly associated with decreased adjusted concentrations of carbamazepine-10,11-trans dihydrodiol (GG vs. GA + AA: P = 0.04) and CBZD:CBZE ratio (GG vs. AA: P = 0.008; GG vs. GA + AA: P = 0.0008). 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide 202-206 epoxide hydrolase 1 Homo sapiens 13-18 31650507-10 2019 Conclusion EPHX1 rs1051740 and rs2234922 polymorphisms may affect the carbamazepine metabolism; but carbamazepine resistance was not related to any of the single nucleotide polymorphisms investigated. Carbamazepine 70-83 epoxide hydrolase 1 Homo sapiens 11-16 31465212-3 2019 To identify the controlling features of S-site oxygen uptake, related Ni(mu-EPhX)(mu-S"N2)Fe (E = S or Se, Fe = (eta5-C5H5)FeII(CO)) complexes were electronically tuned by the para-substituent on mu-EPhX (X = CF3, Cl, H, OMe, NMe2) and compared in aspects of communication between Ni and Fe. Oxygen 47-53 epoxide hydrolase 1 Homo sapiens 76-80 31465212-3 2019 To identify the controlling features of S-site oxygen uptake, related Ni(mu-EPhX)(mu-S"N2)Fe (E = S or Se, Fe = (eta5-C5H5)FeII(CO)) complexes were electronically tuned by the para-substituent on mu-EPhX (X = CF3, Cl, H, OMe, NMe2) and compared in aspects of communication between Ni and Fe. Iron 90-92 epoxide hydrolase 1 Homo sapiens 76-80 31465212-4 2019 Both single and double O atom uptake at the chalcogens led to the conversion of the four-membered ring core, Ni(mu-EPhX)(mu-S"N2)Fe, to a five-membered ring Ni-O-E-Fe-S", where an O atom inserts between E and Ni. Nitrogen 124-128 epoxide hydrolase 1 Homo sapiens 115-119 31465212-4 2019 Both single and double O atom uptake at the chalcogens led to the conversion of the four-membered ring core, Ni(mu-EPhX)(mu-S"N2)Fe, to a five-membered ring Ni-O-E-Fe-S", where an O atom inserts between E and Ni. Iron 129-131 epoxide hydrolase 1 Homo sapiens 115-119 31465212-6 2019 Qualitative rates of reaction and ratios of oxygen-uptake products correlate with Hammett parameters of the X substituent on EPhX. Oxygen 44-50 epoxide hydrolase 1 Homo sapiens 125-129 31348278-0 2019 The effect on congenital heart diseases of maternal EPHX1 polymorphisms modified by polycyclic aromatic hydrocarbons exposure. Polycyclic Aromatic Hydrocarbons 84-116 epoxide hydrolase 1 Homo sapiens 52-57 31426537-0 2019 Magneto-Electroluminescence in ITO/MEH-PPV:PEO:LiCF3SO3/Al Polymer Light-Emitting Electrochemical Cells. licf3so3 47-55 epoxide hydrolase 1 Homo sapiens 35-38 31426537-0 2019 Magneto-Electroluminescence in ITO/MEH-PPV:PEO:LiCF3SO3/Al Polymer Light-Emitting Electrochemical Cells. Aluminum 56-58 epoxide hydrolase 1 Homo sapiens 35-38 31426537-0 2019 Magneto-Electroluminescence in ITO/MEH-PPV:PEO:LiCF3SO3/Al Polymer Light-Emitting Electrochemical Cells. Polymers 59-66 epoxide hydrolase 1 Homo sapiens 35-38 31310524-2 2019 We have shown previously that oxetanes are hydrolyzed to diols by human microsomal epoxide hydrolase (mEH). oxetane 30-38 epoxide hydrolase 1 Homo sapiens 72-100 31310524-2 2019 We have shown previously that oxetanes are hydrolyzed to diols by human microsomal epoxide hydrolase (mEH). diols 57-62 epoxide hydrolase 1 Homo sapiens 72-100 31348278-6 2019 A possible modifying effect of PAHs exposure on genetic polymorphisms of EPHX1 was found in susceptibility to CHDs, though no multiplicative-scale interactions between maternal exposure to PAHs and polymorphisms of EPHX1 gene were seento affect the risk of CHDs.The role of EPHX1 gene polymorphisms for CHDs need to be further evaluated, in particularly by interacting with PAHs exposure. Polycyclic Aromatic Hydrocarbons 31-35 epoxide hydrolase 1 Homo sapiens 73-78 31348278-6 2019 A possible modifying effect of PAHs exposure on genetic polymorphisms of EPHX1 was found in susceptibility to CHDs, though no multiplicative-scale interactions between maternal exposure to PAHs and polymorphisms of EPHX1 gene were seento affect the risk of CHDs.The role of EPHX1 gene polymorphisms for CHDs need to be further evaluated, in particularly by interacting with PAHs exposure. Polycyclic Aromatic Hydrocarbons 31-35 epoxide hydrolase 1 Homo sapiens 215-220 31348278-6 2019 A possible modifying effect of PAHs exposure on genetic polymorphisms of EPHX1 was found in susceptibility to CHDs, though no multiplicative-scale interactions between maternal exposure to PAHs and polymorphisms of EPHX1 gene were seento affect the risk of CHDs.The role of EPHX1 gene polymorphisms for CHDs need to be further evaluated, in particularly by interacting with PAHs exposure. Polycyclic Aromatic Hydrocarbons 31-35 epoxide hydrolase 1 Homo sapiens 215-220 30984783-0 2019 Retracted: Influence of Two Common Polymorphisms in the EPHX1 Gene on Warfarin Maintenance Dosage: A Meta-Analysis. Warfarin 70-78 epoxide hydrolase 1 Homo sapiens 56-61 31164100-0 2019 Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population. Carbamazepine 60-73 epoxide hydrolase 1 Homo sapiens 10-15 31164100-0 2019 Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population. Carbamazepine 103-116 epoxide hydrolase 1 Homo sapiens 10-15 31164100-3 2019 Herein, we investigated the association between Carbamazepine-resistant (CBZ-resistant) epilepsy and EPHX1 methylation in a northern Han Chinese population, and conducted an analysis of clinical risk factors for CBZ-resistant epilepsy. Carbamazepine 48-61 epoxide hydrolase 1 Homo sapiens 101-106 30644597-1 2019 Microsomal epoxide hyrolase 1 (EPHX1) is a critical biotransformation enzyme and participants in both the detoxification and activation of potentially genotoxic epoxides. Epoxy Compounds 161-169 epoxide hydrolase 1 Homo sapiens 31-36 30644597-2 2019 In this study, we firstly aimed to investigate the role of EPHX1 in the chemoresistance of acute myeloid leukemic cells to aclarubicin (ACM) and mitoxantrone (MIT). Aclarubicin 123-134 epoxide hydrolase 1 Homo sapiens 59-64 30644597-2 2019 In this study, we firstly aimed to investigate the role of EPHX1 in the chemoresistance of acute myeloid leukemic cells to aclarubicin (ACM) and mitoxantrone (MIT). Mitoxantrone 145-157 epoxide hydrolase 1 Homo sapiens 59-64 30644597-2 2019 In this study, we firstly aimed to investigate the role of EPHX1 in the chemoresistance of acute myeloid leukemic cells to aclarubicin (ACM) and mitoxantrone (MIT). Mitoxantrone 159-162 epoxide hydrolase 1 Homo sapiens 59-64 31503800-0 2019 Low threshold optically pumped lasing from MEH-PPV quasi-periodic photonic crystal microcavity. lasing 31-37 epoxide hydrolase 1 Homo sapiens 43-46 31503800-1 2019 An optically pumped two-dimensional organic quasi-crystal microcavity laser is demonstrated based on conjugated polymer poly(2-methoxy, 5-(2"-3ethylhexyloxy)-1,4-phenylene vinylene) (MEH-PPV). polymer poly(2-methoxy, 5-(2"-3ethylhexyloxy)-1,4-phenylene vinylene) 112-181 epoxide hydrolase 1 Homo sapiens 183-186 31164100-3 2019 Herein, we investigated the association between Carbamazepine-resistant (CBZ-resistant) epilepsy and EPHX1 methylation in a northern Han Chinese population, and conducted an analysis of clinical risk factors for CBZ-resistant epilepsy. Carbamazepine 73-76 epoxide hydrolase 1 Homo sapiens 101-106 31164100-9 2019 However, a significant difference of methylation levels located in NC_000001.11 (225,806,929.....225807108) of the EPHX1 promoter was found in CBZ-resistant patients, which was much higher than CBZ-sensitive and controls. Carbamazepine 143-146 epoxide hydrolase 1 Homo sapiens 115-120 31164100-9 2019 However, a significant difference of methylation levels located in NC_000001.11 (225,806,929.....225807108) of the EPHX1 promoter was found in CBZ-resistant patients, which was much higher than CBZ-sensitive and controls. Carbamazepine 194-197 epoxide hydrolase 1 Homo sapiens 115-120 31164100-10 2019 Additionally, there was a significant positive correlation between seizure frequency, disease course and EPHX1 methylation in CBZ-resistant group. Carbamazepine 126-129 epoxide hydrolase 1 Homo sapiens 105-110 31164100-11 2019 CONCLUSION: Methylation levels in EPHX1 promoter associated with CBZ-resistant epilepsy significantly. Carbamazepine 65-68 epoxide hydrolase 1 Homo sapiens 34-39 31164100-12 2019 EPHX1 methylation may be the potential marker for CBZ resistance prior to the CBZ therapy and potential target for treatments. Carbamazepine 50-53 epoxide hydrolase 1 Homo sapiens 0-5 31164100-12 2019 EPHX1 methylation may be the potential marker for CBZ resistance prior to the CBZ therapy and potential target for treatments. Carbamazepine 78-81 epoxide hydrolase 1 Homo sapiens 0-5 30642448-8 2019 CONCLUSION: Nonsynonymous EPHX1 and TCF7L2 SNVs might be associated with clinically significant crizotinib-associated AEs. Crizotinib 96-106 epoxide hydrolase 1 Homo sapiens 26-31 30724559-4 2019 Compounds 2HH, 2MeH, and 2 protonate to give rare examples of Fe-SH and Fe-S2 hydrides. fe-sh 62-67 epoxide hydrolase 1 Homo sapiens 16-19 30724559-4 2019 Compounds 2HH, 2MeH, and 2 protonate to give rare examples of Fe-SH and Fe-S2 hydrides. fe-s2 hydrides 72-86 epoxide hydrolase 1 Homo sapiens 16-19 30228819-7 2018 As this reactive metabolite is detoxified mainly by enzymatic reactions, involving microsomal epoxide hydrolase and/or GSH-S-transferases and these enzymes are polymorphically expressed in humans, arene oxide toxicity is increased when epoxide hydrolase or GSH-S-transferases is either defective or inhibited or a depletion of intracellular glutathione levels is taking place. Benzene oxide 197-208 epoxide hydrolase 1 Homo sapiens 83-111 30228819-7 2018 As this reactive metabolite is detoxified mainly by enzymatic reactions, involving microsomal epoxide hydrolase and/or GSH-S-transferases and these enzymes are polymorphically expressed in humans, arene oxide toxicity is increased when epoxide hydrolase or GSH-S-transferases is either defective or inhibited or a depletion of intracellular glutathione levels is taking place. Glutathione 341-352 epoxide hydrolase 1 Homo sapiens 83-111 29605894-10 2018 Since EPHX1 enzyme is essential in cellular defense against epoxides, the diminished enzymatic activity conferred by the variant allele C could explain the risk associations found for i-AML. Epoxy Compounds 60-68 epoxide hydrolase 1 Homo sapiens 6-11 30068188-1 2018 The Frenkel-Holstein model in the Born-Oppenheimer regime is used to interpret temperature-dependent photoluminescence spectra of solutions made with the poly(p-phenylene vinylene) derivative MEH-PPV. oppenheimer 39-50 epoxide hydrolase 1 Homo sapiens 192-195 30068188-1 2018 The Frenkel-Holstein model in the Born-Oppenheimer regime is used to interpret temperature-dependent photoluminescence spectra of solutions made with the poly(p-phenylene vinylene) derivative MEH-PPV. poly(4-phenylenevinylene) 154-180 epoxide hydrolase 1 Homo sapiens 192-195 30960725-0 2018 Influence of SiO2/TiO2 Nanocomposite on the Optoelectronic Properties of PFO/MEH-PPV-Based OLED Devices. Silicon Dioxide 13-17 epoxide hydrolase 1 Homo sapiens 77-80 30960725-0 2018 Influence of SiO2/TiO2 Nanocomposite on the Optoelectronic Properties of PFO/MEH-PPV-Based OLED Devices. titanium dioxide 18-22 epoxide hydrolase 1 Homo sapiens 77-80 30960725-5 2018 The enhancement of MEH-PPV electroluminescence peaks in the hybrids in the presence of SiO2/TiO2 nanocomposites is not only a result of the Forster resonance energy transfer, but also of hole-electron recombination, which is of greater significance. Silicon Dioxide 87-91 epoxide hydrolase 1 Homo sapiens 19-22 30960725-5 2018 The enhancement of MEH-PPV electroluminescence peaks in the hybrids in the presence of SiO2/TiO2 nanocomposites is not only a result of the Forster resonance energy transfer, but also of hole-electron recombination, which is of greater significance. titanium dioxide 92-96 epoxide hydrolase 1 Homo sapiens 19-22 29605894-0 2018 EPHX1 rs1051740 T>C (Tyr113His) is strongly associated with acute myeloid leukemia and KMT2A rearrangements in early age. tyr113his 24-33 epoxide hydrolase 1 Homo sapiens 0-5 29996894-13 2018 In the EWAS of the subcohort, 25(OH)D was associated (q < 0.05) with methylation at cg24350360 (EPHX1; p = 3.4 x 10-8), cg06177555 (SPN; p = 9.8 x 10-8), and cg13243168 (SMARCD2; p = 2.9 x 10-7). cg24350360 87-97 epoxide hydrolase 1 Homo sapiens 99-104 29605894-11 2018 In conclusion, EPHX1 rs1051740 plays an important role in i-AML"s genetic susceptibility by modulating the carcinogenic effects of epoxide exposures in the bone marrow. Epoxy Compounds 131-138 epoxide hydrolase 1 Homo sapiens 15-20 29054760-1 2018 The aim of this study was to investigate the possible effects of EPHX1 and VKORC1L1 polymorphisms on variability of responses to warfarin. Warfarin 129-137 epoxide hydrolase 1 Homo sapiens 65-70 29449907-1 2018 Hybrid conjugated polymer/fullerene filaments based on MEH-PPV/PVP/PCBM were prepared by electrospinning, and their properties were assessed by scanning electron, atomic and lateral-force, tunneling, and confocal microscopies, as well as by attenuated-total-reflection Fourier transform infrared spectroscopy, photoluminescence quantum yield, and spatially resolved fluorescence. Polymers 18-25 epoxide hydrolase 1 Homo sapiens 55-58 29449907-1 2018 Hybrid conjugated polymer/fullerene filaments based on MEH-PPV/PVP/PCBM were prepared by electrospinning, and their properties were assessed by scanning electron, atomic and lateral-force, tunneling, and confocal microscopies, as well as by attenuated-total-reflection Fourier transform infrared spectroscopy, photoluminescence quantum yield, and spatially resolved fluorescence. Fullerenes 26-35 epoxide hydrolase 1 Homo sapiens 55-58 29054760-6 2018 Multivariate analysis showed that EPHX1 rs1877724 and VKORC1L1 rs4072879 accounted for 1.5% and 1.3% of the warfarin dose variability. Warfarin 108-116 epoxide hydrolase 1 Homo sapiens 34-39 29054760-0 2018 Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses. Vitamin K 17-26 epoxide hydrolase 1 Homo sapiens 42-47 29054760-8 2018 This study showed that polymorphisms of EPHX1 and VKORC1L1 could be determinants of stable warfarin doses. Warfarin 91-99 epoxide hydrolase 1 Homo sapiens 40-45 28789952-0 2017 The Tyr113His T/C rs1051740 and "very slow" phenotype of the EPHX1 gene alters miR-26b-5p and miR-1207-5p expression in pregnancy. tyr113his 4-13 epoxide hydrolase 1 Homo sapiens 61-66 29292455-4 2018 In this work, we monitored the chain scission of the model polymer MEH-PPV in chloroform solutions under different conditions by assessing its molecular weight using gel permeation chromatography and optical spectral measurements. Chloroform 78-88 epoxide hydrolase 1 Homo sapiens 67-70 28789952-6 2017 RESULTS: Mothers with the Tyr113His SNP had low iron levels [TT vs. TC+CC: mean difference (MD)=0.67g/dl; p=0.0167], LBW [TT vs. TC+CC: MD=189.30g; p=0.0067], and low EPHX1 expression; p<0.0001. tyr113his 26-35 epoxide hydrolase 1 Homo sapiens 167-172 28789952-11 2017 CONCLUSION: The Tyr113His T/C variant of rs1051740 and VS phenotype alters EPHX1, miR-26b-5p and miR-1207-5p expression, and contributes towards low blood iron levels and LBW. tyr113his 16-25 epoxide hydrolase 1 Homo sapiens 75-80 28789952-11 2017 CONCLUSION: The Tyr113His T/C variant of rs1051740 and VS phenotype alters EPHX1, miR-26b-5p and miR-1207-5p expression, and contributes towards low blood iron levels and LBW. Iron 155-159 epoxide hydrolase 1 Homo sapiens 75-80 28820457-0 2017 Role of CYP2C9, CYP2C19 and EPHX Polymorphism in the Pharmacokinetic of Phenytoin: A Study on Uruguayan Caucasian Subjects. Phenytoin 72-81 epoxide hydrolase 1 Homo sapiens 28-32 29041449-4 2017 An conjugated polymer poly (2-methoxy-5-(2"-ethyl-hexyloxy)-p-phenylenevinylene (MEH-PPV) film is coated on the inner surface of glass substrate to dramatically reduce the lasing threshold, which is 20 times lower than that of dye-doped microcavity laser. polymer poly (2-methoxy-5-(2"-ethyl-hexyloxy)-p-phenylenevinylene 14-79 epoxide hydrolase 1 Homo sapiens 81-84 29041449-4 2017 An conjugated polymer poly (2-methoxy-5-(2"-ethyl-hexyloxy)-p-phenylenevinylene (MEH-PPV) film is coated on the inner surface of glass substrate to dramatically reduce the lasing threshold, which is 20 times lower than that of dye-doped microcavity laser. lasing 172-178 epoxide hydrolase 1 Homo sapiens 81-84 28820457-3 2017 This intermediate can also be converted into PHT dihydrodiol by microsomal epoxide hydrolase (EPHX). phenytoin dihydrodiol 45-60 epoxide hydrolase 1 Homo sapiens 64-92 28820457-3 2017 This intermediate can also be converted into PHT dihydrodiol by microsomal epoxide hydrolase (EPHX). phenytoin dihydrodiol 45-60 epoxide hydrolase 1 Homo sapiens 94-98 28820457-10 2017 Apart from being responsible for the production of the dihydrodiol metabolite, EPHX also seemed to contribute to pHPPH formation when its activity is low. trans-1,2-dihydro-1,2-naphthalenediol 55-66 epoxide hydrolase 1 Homo sapiens 79-83 28079798-9 2017 In the limited sample set, we also found that novel genetic predictors (CYP1A2, CYP3A4, APOE, EPHX1, CYP4F2, and VKORC1 rs2884737) may be associated with warfarin dosing. Warfarin 154-162 epoxide hydrolase 1 Homo sapiens 94-99 28600384-0 2017 Oxetane Substrates of Human Microsomal Epoxide Hydrolase. oxetane 0-7 epoxide hydrolase 1 Homo sapiens 28-56 28600384-2 2017 A series of oxetane-containing analogs was studied and we provide the first direct evidence of oxetane hydrolysis by human recombinant microsomal epoxide hydrolase (mEH). oxetane 12-19 epoxide hydrolase 1 Homo sapiens 135-163 28600384-2 2017 A series of oxetane-containing analogs was studied and we provide the first direct evidence of oxetane hydrolysis by human recombinant microsomal epoxide hydrolase (mEH). oxetane 95-102 epoxide hydrolase 1 Homo sapiens 135-163 30023675-7 2017 We use the instrument to characterize the slow photochemical degradation kinetics of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) in o-dichlorobenzene. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 85-142 epoxide hydrolase 1 Homo sapiens 144-147 30023675-7 2017 We use the instrument to characterize the slow photochemical degradation kinetics of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) in o-dichlorobenzene. 2-dichlorobenzene 156-173 epoxide hydrolase 1 Homo sapiens 144-147 30023675-10 2017 We characterize the photochemical degradation kinetics of MEH-PPV in o-dichlorobenzene solutions placed in the cuvette versus that in the capillary fiber. 2-dichlorobenzene 69-86 epoxide hydrolase 1 Homo sapiens 58-61 28221806-0 2017 Absorption and Quantum Yield of Single Conjugated Polymer Poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) Molecules. polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 50-115 epoxide hydrolase 1 Homo sapiens 117-120 28221806-1 2017 We simultaneously measured the absorption and emission of single conjugated polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) molecules in a poly(methyl methacrylate) (PMMA) matrix using near-critical xenon to enhance the photothermal contrast for direct absorption measurements. polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 76-141 epoxide hydrolase 1 Homo sapiens 143-146 28221806-1 2017 We simultaneously measured the absorption and emission of single conjugated polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) molecules in a poly(methyl methacrylate) (PMMA) matrix using near-critical xenon to enhance the photothermal contrast for direct absorption measurements. Polymethyl Methacrylate 167-192 epoxide hydrolase 1 Homo sapiens 143-146 28221806-1 2017 We simultaneously measured the absorption and emission of single conjugated polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) molecules in a poly(methyl methacrylate) (PMMA) matrix using near-critical xenon to enhance the photothermal contrast for direct absorption measurements. Polymethyl Methacrylate 194-198 epoxide hydrolase 1 Homo sapiens 143-146 28221806-1 2017 We simultaneously measured the absorption and emission of single conjugated polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) molecules in a poly(methyl methacrylate) (PMMA) matrix using near-critical xenon to enhance the photothermal contrast for direct absorption measurements. Xenon 227-232 epoxide hydrolase 1 Homo sapiens 143-146 28236031-1 2017 The chromism observed in the MEH-PPV polymer in tetrahydrofuran (THF) solution is discussed as a function of the structural morphology of the backbone chains. tetrahydrofuran 48-63 epoxide hydrolase 1 Homo sapiens 29-32 28236031-1 2017 The chromism observed in the MEH-PPV polymer in tetrahydrofuran (THF) solution is discussed as a function of the structural morphology of the backbone chains. tetrahydrofuran 65-68 epoxide hydrolase 1 Homo sapiens 29-32 28295982-3 2017 Here, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) nanoparticles are prepared from MEH-PPV polymer and the change in photophysical properties upon formation of polymer nanoparticles (PNPs) from the molecular state are investigated by using steady-state and time-resolved spectroscopy. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 6-63 epoxide hydrolase 1 Homo sapiens 65-68 28295982-3 2017 Here, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) nanoparticles are prepared from MEH-PPV polymer and the change in photophysical properties upon formation of polymer nanoparticles (PNPs) from the molecular state are investigated by using steady-state and time-resolved spectroscopy. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 6-63 epoxide hydrolase 1 Homo sapiens 106-109 28295982-3 2017 Here, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) nanoparticles are prepared from MEH-PPV polymer and the change in photophysical properties upon formation of polymer nanoparticles (PNPs) from the molecular state are investigated by using steady-state and time-resolved spectroscopy. Polymers 114-121 epoxide hydrolase 1 Homo sapiens 65-68 28295982-4 2017 Nanocomposites are constructed by adding hexadecylamine-functionalized positively charged MEH-PPV PNPs to a solution of negatively charged r-GO. hexadecylamine 41-55 epoxide hydrolase 1 Homo sapiens 90-93 27698464-1 2016 In this study, hybrid perovskite solar cells are fabricated using poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) and poly(3-hexylthiophene-2,5-diyl) (P3HT) as dopant-free hole-transporting materials (HTMs), and two solution processes (one- and two-step methods, respectively) for preparing methylammonium lead iodide perovskite. perovskite 22-32 epoxide hydrolase 1 Homo sapiens 125-128 29630810-6 2017 This results show that the MEH-PPV/ZnO thin films gives good performance and is relevant for applications in optoelectronic devices such as a negative differential resistance. Zinc Oxide 35-38 epoxide hydrolase 1 Homo sapiens 27-30 27632229-3 2016 We genotyped 12 single nucleotide polymorphisms in genes (CYP2C9, VKORC1, CYP4F2, GGCX, EPHX1, CALU) associated with altered warfarin dose requirements and tested their associations with international normalized ratio variability (INRVAR) and percent time in therapeutic range in European-Americans and African-Americans. Warfarin 125-133 epoxide hydrolase 1 Homo sapiens 88-93 27795752-2 2016 We show that silver-enhancement of gold nanostars reduces the pumping threshold for coherent random lasing substantially for both a typical dye (R6G) and a typical fluorescent polymer (MEH-PPV). Silver 13-19 epoxide hydrolase 1 Homo sapiens 185-188 27795752-2 2016 We show that silver-enhancement of gold nanostars reduces the pumping threshold for coherent random lasing substantially for both a typical dye (R6G) and a typical fluorescent polymer (MEH-PPV). Polymers 176-183 epoxide hydrolase 1 Homo sapiens 185-188 27698464-1 2016 In this study, hybrid perovskite solar cells are fabricated using poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) and poly(3-hexylthiophene-2,5-diyl) (P3HT) as dopant-free hole-transporting materials (HTMs), and two solution processes (one- and two-step methods, respectively) for preparing methylammonium lead iodide perovskite. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 66-123 epoxide hydrolase 1 Homo sapiens 125-128 27698464-3 2016 This result shows that non-doped MEH-PPV is a suitable, low-cost HTM for efficient polymer-based perovskite solar cells. Polymers 83-90 epoxide hydrolase 1 Homo sapiens 33-36 27698464-3 2016 This result shows that non-doped MEH-PPV is a suitable, low-cost HTM for efficient polymer-based perovskite solar cells. perovskite 97-107 epoxide hydrolase 1 Homo sapiens 33-36 27256986-11 2016 The substrate specificity of microsomal epoxide hydrolase should therefore be expanded to include not only epoxides but also the oxetanyl ring system present in AZD1979. AZD1979 161-168 epoxide hydrolase 1 Homo sapiens 29-57 27256986-0 2016 Discovery of a Novel Microsomal Epoxide Hydrolase-Catalyzed Hydration of a Spiro Oxetane. spiro oxetane 75-88 epoxide hydrolase 1 Homo sapiens 21-49 26922413-7 2016 Our study results suggest that genetic polymorphisms of COX2, EPHX1, CAT, and SOD2 modify the association of BPA with liver function. bisphenol A 109-112 epoxide hydrolase 1 Homo sapiens 62-67 27256986-9 2016 The formation of M1 was substantially inhibited by progabide, a microsomal epoxide hydrolase inhibitor, but not by trans-4-[4-(1-adamantylcarbamoylamino)cyclohexyloxy]benzoic acid, a soluble epoxide hydrolase inhibitor. progabide 51-60 epoxide hydrolase 1 Homo sapiens 64-92 27256986-11 2016 The substrate specificity of microsomal epoxide hydrolase should therefore be expanded to include not only epoxides but also the oxetanyl ring system present in AZD1979. Epoxy Compounds 107-115 epoxide hydrolase 1 Homo sapiens 29-57 26602704-1 2016 The coordination chemistry of the 1,2-BN-cyclohexanes 2,2-R2 -1,2-B,N-C4 H10 (R2 =HH, MeH, Me2 ) with Ir and Rh metal fragments has been studied. 1,2-bn-cyclohexanes 34-53 epoxide hydrolase 1 Homo sapiens 86-89 28071611-1 2016 Microsomal epoxide hydrolase (mEH) is a crucial biotransformation enzyme that has capability to metabolize a large number of structurally divergent, highly reactive epoxides, and numerous environmentally exposed carcinogens. Epoxy Compounds 165-173 epoxide hydrolase 1 Homo sapiens 0-28 26840748-2 2016 1,2-Dihydro-1,2-dihydroxynaphthalene (NA-dihydrodiol) is a major metabolite of NA generated by microsomal epoxide hydrolase (mEH). 1,2-Dihydronaphthalene-1,2-diol 0-36 epoxide hydrolase 1 Homo sapiens 95-123 26840748-2 2016 1,2-Dihydro-1,2-dihydroxynaphthalene (NA-dihydrodiol) is a major metabolite of NA generated by microsomal epoxide hydrolase (mEH). na-dihydrodiol 38-52 epoxide hydrolase 1 Homo sapiens 95-123 27276192-0 2016 Effects of EPHX1 and CYP3A4*22 genetic polymorphisms on carbamazepine metabolism and drug response among Tunisian epileptic patients. Carbamazepine 56-69 epoxide hydrolase 1 Homo sapiens 11-16 27276192-1 2016 The aim of this study was to evaluate the impact of polymorphisms in the EPHX1 (c.416A > G, c.337T > C) and CYP3A4*22 genes involved in carbamazepine (CBZ) metabolism and pharmacoresistance among 118 Tunisian patients with epilepsy under maintenance dose of CBZ. Carbamazepine 142-155 epoxide hydrolase 1 Homo sapiens 73-78 27276192-1 2016 The aim of this study was to evaluate the impact of polymorphisms in the EPHX1 (c.416A > G, c.337T > C) and CYP3A4*22 genes involved in carbamazepine (CBZ) metabolism and pharmacoresistance among 118 Tunisian patients with epilepsy under maintenance dose of CBZ. Carbamazepine 157-160 epoxide hydrolase 1 Homo sapiens 73-78 27276192-1 2016 The aim of this study was to evaluate the impact of polymorphisms in the EPHX1 (c.416A > G, c.337T > C) and CYP3A4*22 genes involved in carbamazepine (CBZ) metabolism and pharmacoresistance among 118 Tunisian patients with epilepsy under maintenance dose of CBZ. Carbamazepine 264-267 epoxide hydrolase 1 Homo sapiens 73-78 27276192-4 2016 Both variants of EPHX1 c.416A > G and c.337T > C are significantly associated with higher metabolic ratio CBZ-E:CBZ and seem to decrease the activity of the epoxide hydrolase. cbz-e 112-117 epoxide hydrolase 1 Homo sapiens 17-22 27276192-4 2016 Both variants of EPHX1 c.416A > G and c.337T > C are significantly associated with higher metabolic ratio CBZ-E:CBZ and seem to decrease the activity of the epoxide hydrolase. Carbamazepine 112-115 epoxide hydrolase 1 Homo sapiens 17-22 26655675-11 2016 We found significant gene-environment interaction between PAH and four SNPs (EPHX1, (rs2854461), STAT4 (rs16833215), XPC (rs2228001 and rs2733532)), which became non-significant after adjusting for multiple comparisons. Polycyclic Aromatic Hydrocarbons 58-61 epoxide hydrolase 1 Homo sapiens 77-82 32263361-1 2016 Near-infrared-emitting polymer dots were prepared by encapsulating the dye NIR775 into the matrix of MEH-PPV dots using a nanoscale precipitation method, and their application for long-term tumor cell tracking in vivo is demonstrated for the first time. Polymers 23-30 epoxide hydrolase 1 Homo sapiens 101-104 32263361-1 2016 Near-infrared-emitting polymer dots were prepared by encapsulating the dye NIR775 into the matrix of MEH-PPV dots using a nanoscale precipitation method, and their application for long-term tumor cell tracking in vivo is demonstrated for the first time. nir775 75-81 epoxide hydrolase 1 Homo sapiens 101-104 26653672-0 2016 Encapsulation of MEH-PPV:PCBM Hybrids in the Cores of Block Copolymer Micellar Assemblies: Photoinduced Electron Transfer in a Nanoscale Donor-Acceptor System. PCBM 25-29 epoxide hydrolase 1 Homo sapiens 17-20 26653672-0 2016 Encapsulation of MEH-PPV:PCBM Hybrids in the Cores of Block Copolymer Micellar Assemblies: Photoinduced Electron Transfer in a Nanoscale Donor-Acceptor System. copolymer 60-69 epoxide hydrolase 1 Homo sapiens 17-20 26653672-2 2016 To this end, aqueous dispersions of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) nanoparticles were first prepared by solubilization of the polymer in the cores of poly(oxyethylene)-poly(oxypropylene)-poly(oxyethylene) triblock copolymer, Pluronic F-127 micelles. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 36-93 epoxide hydrolase 1 Homo sapiens 95-98 26653672-6 2016 When MEH-PPV micelles were blended by the addition of controlled amounts of [6,6]-phenyl-C61-butyric acid methyl ester (PCBM), the observed correspondence of photoluminescence emission quenching, quantum yield decreases, and emission lifetime shortening with increasing PCBM concentration indicated efficient photoinduced donor-to-acceptor charge transfer between MEH-PPV and the fullerenes in the cores of the micelles, an assignment that was confirmed by transient absorption spectroscopic monitoring of carrier photogeneration and recombination. (6,6)-phenyl C61-butyric acid methyl ester 76-118 epoxide hydrolase 1 Homo sapiens 5-8 26653672-6 2016 When MEH-PPV micelles were blended by the addition of controlled amounts of [6,6]-phenyl-C61-butyric acid methyl ester (PCBM), the observed correspondence of photoluminescence emission quenching, quantum yield decreases, and emission lifetime shortening with increasing PCBM concentration indicated efficient photoinduced donor-to-acceptor charge transfer between MEH-PPV and the fullerenes in the cores of the micelles, an assignment that was confirmed by transient absorption spectroscopic monitoring of carrier photogeneration and recombination. (6,6)-phenyl C61-butyric acid methyl ester 76-118 epoxide hydrolase 1 Homo sapiens 364-367 26653672-6 2016 When MEH-PPV micelles were blended by the addition of controlled amounts of [6,6]-phenyl-C61-butyric acid methyl ester (PCBM), the observed correspondence of photoluminescence emission quenching, quantum yield decreases, and emission lifetime shortening with increasing PCBM concentration indicated efficient photoinduced donor-to-acceptor charge transfer between MEH-PPV and the fullerenes in the cores of the micelles, an assignment that was confirmed by transient absorption spectroscopic monitoring of carrier photogeneration and recombination. PCBM 120-124 epoxide hydrolase 1 Homo sapiens 5-8 26653672-6 2016 When MEH-PPV micelles were blended by the addition of controlled amounts of [6,6]-phenyl-C61-butyric acid methyl ester (PCBM), the observed correspondence of photoluminescence emission quenching, quantum yield decreases, and emission lifetime shortening with increasing PCBM concentration indicated efficient photoinduced donor-to-acceptor charge transfer between MEH-PPV and the fullerenes in the cores of the micelles, an assignment that was confirmed by transient absorption spectroscopic monitoring of carrier photogeneration and recombination. PCBM 270-274 epoxide hydrolase 1 Homo sapiens 5-8 26653672-6 2016 When MEH-PPV micelles were blended by the addition of controlled amounts of [6,6]-phenyl-C61-butyric acid methyl ester (PCBM), the observed correspondence of photoluminescence emission quenching, quantum yield decreases, and emission lifetime shortening with increasing PCBM concentration indicated efficient photoinduced donor-to-acceptor charge transfer between MEH-PPV and the fullerenes in the cores of the micelles, an assignment that was confirmed by transient absorption spectroscopic monitoring of carrier photogeneration and recombination. Fullerenes 380-390 epoxide hydrolase 1 Homo sapiens 5-8 26602704-1 2016 The coordination chemistry of the 1,2-BN-cyclohexanes 2,2-R2 -1,2-B,N-C4 H10 (R2 =HH, MeH, Me2 ) with Ir and Rh metal fragments has been studied. PARP14 inhibitor H10 73-76 epoxide hydrolase 1 Homo sapiens 86-89 26438977-1 2015 The relationship between photostability and conformation of 2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene (MEH-PPV) conjugated polymers was studied via excitation polarization modulation depth (M) measurements. 2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene 60-112 epoxide hydrolase 1 Homo sapiens 114-117 26555147-0 2015 Polymorphic Variants of SCN1A and EPHX1 Influence Plasma Carbamazepine Concentration, Metabolism and Pharmacoresistance in a Population of Kosovar Albanian Epileptic Patients. Carbamazepine 57-70 epoxide hydrolase 1 Homo sapiens 34-39 26555147-2 2015 MATERIALS & METHODS: Five SNPs in two candidate genes influencing CBZ transport and metabolism, namely ABCB1 or EPHX1, and CBZ response SCN1A (sodium channel) were genotyped in 145 epileptic patients treated with CBZ as monotherapy and 100 age and sex matched healthy controls. Adenosine Monophosphate 11-14 epoxide hydrolase 1 Homo sapiens 116-121 26555147-2 2015 MATERIALS & METHODS: Five SNPs in two candidate genes influencing CBZ transport and metabolism, namely ABCB1 or EPHX1, and CBZ response SCN1A (sodium channel) were genotyped in 145 epileptic patients treated with CBZ as monotherapy and 100 age and sex matched healthy controls. Carbamazepine 70-73 epoxide hydrolase 1 Homo sapiens 116-121 26555147-11 2015 SNPs in EPHX1 gene are influencing CBZ metabolism and disposition. Carbamazepine 35-38 epoxide hydrolase 1 Homo sapiens 8-13 26369059-3 2015 Results showed that the spinning rate of photoactive layer at 2000 rpm obtained the optimum thickness, moreover, solvent annealing firstly then the deposition of the positive electrode, finally thermal annealing at 140 degrees C contributing to the better reorganization for polymer and CuInS2 QDs to form the more stable phase-segregated state in the photovoltaic layer in the MEH-PPV-CuInS2/ZnO-NAs solar cells, obtaining the maximum power conversion efficiency of 2.54% under the monochromic illumination at 470 nm. Polymers 275-282 epoxide hydrolase 1 Homo sapiens 378-381 26556528-2 2015 The nanoparticles are formed by hydrophobic interaction of the semiconducting polymer MEH-PPV (poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene]) with the fullerene PCBM (phenyl-C61-butyric acid methyl ester) in the presence of a non-compatible solvent. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene 95-151 epoxide hydrolase 1 Homo sapiens 86-89 26556528-3 2015 MEH-PPV has a high extinction coefficient that leads to high rates of triplet formation, and efficient charge and energy transfer to the fullerene PCBM. Fullerenes 137-146 epoxide hydrolase 1 Homo sapiens 0-3 26556528-3 2015 MEH-PPV has a high extinction coefficient that leads to high rates of triplet formation, and efficient charge and energy transfer to the fullerene PCBM. PCBM 147-151 epoxide hydrolase 1 Homo sapiens 0-3 26216302-1 2015 Microsomal epoxide hydrolase (EPHX1) is an evolutionarily highly conserved biotransformation enzyme for converting epoxides to diols. Epoxy Compounds 115-123 epoxide hydrolase 1 Homo sapiens 0-28 26216302-1 2015 Microsomal epoxide hydrolase (EPHX1) is an evolutionarily highly conserved biotransformation enzyme for converting epoxides to diols. Epoxy Compounds 115-123 epoxide hydrolase 1 Homo sapiens 30-35 26216302-1 2015 Microsomal epoxide hydrolase (EPHX1) is an evolutionarily highly conserved biotransformation enzyme for converting epoxides to diols. diols 127-132 epoxide hydrolase 1 Homo sapiens 0-28 26216302-1 2015 Microsomal epoxide hydrolase (EPHX1) is an evolutionarily highly conserved biotransformation enzyme for converting epoxides to diols. diols 127-132 epoxide hydrolase 1 Homo sapiens 30-35 25980659-3 2015 A dependence on the conjugation length of the polymer chains which was favored by heating of the film, was observed, and irradiation generated a blue-shift in MEH-PPV and Ru(bpy)3. Polymers 46-53 epoxide hydrolase 1 Homo sapiens 159-162 26016517-6 2015 These observations contrast other conjugated polymers such as MEH-PPV where much slower intrachain energy transfer was reported. Polymers 45-53 epoxide hydrolase 1 Homo sapiens 62-65 26369059-1 2015 This paper reported ternary MEH-PPV-CuInS2/ZnO solar cells, which were fabricated with the mixture of poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene vinylene) (MEH-PPV) and CuInS2 quantum dots (QDs) as photovoltaic layer and ZnO nanorod arrays (ZnO-NAs) as electron acceptor. cuins2 36-42 epoxide hydrolase 1 Homo sapiens 28-31 26369059-1 2015 This paper reported ternary MEH-PPV-CuInS2/ZnO solar cells, which were fabricated with the mixture of poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene vinylene) (MEH-PPV) and CuInS2 quantum dots (QDs) as photovoltaic layer and ZnO nanorod arrays (ZnO-NAs) as electron acceptor. Zinc Oxide 43-46 epoxide hydrolase 1 Homo sapiens 28-31 25893850-2 2015 We have developed the guided in situ polymerization of poly(2-methoxy-5-(2"-ethylhexyloxy)-p-phenylenevinylene) (MEH-PPV) in porous titania films by means of surface functionalization. poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 55-111 epoxide hydrolase 1 Homo sapiens 113-116 26369059-1 2015 This paper reported ternary MEH-PPV-CuInS2/ZnO solar cells, which were fabricated with the mixture of poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene vinylene) (MEH-PPV) and CuInS2 quantum dots (QDs) as photovoltaic layer and ZnO nanorod arrays (ZnO-NAs) as electron acceptor. poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene vinylene) 102-160 epoxide hydrolase 1 Homo sapiens 28-31 26369059-1 2015 This paper reported ternary MEH-PPV-CuInS2/ZnO solar cells, which were fabricated with the mixture of poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene vinylene) (MEH-PPV) and CuInS2 quantum dots (QDs) as photovoltaic layer and ZnO nanorod arrays (ZnO-NAs) as electron acceptor. cuins2 175-181 epoxide hydrolase 1 Homo sapiens 28-31 26369059-1 2015 This paper reported ternary MEH-PPV-CuInS2/ZnO solar cells, which were fabricated with the mixture of poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene vinylene) (MEH-PPV) and CuInS2 quantum dots (QDs) as photovoltaic layer and ZnO nanorod arrays (ZnO-NAs) as electron acceptor. Zinc Oxide 227-230 epoxide hydrolase 1 Homo sapiens 28-31 26369059-1 2015 This paper reported ternary MEH-PPV-CuInS2/ZnO solar cells, which were fabricated with the mixture of poly(2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene vinylene) (MEH-PPV) and CuInS2 quantum dots (QDs) as photovoltaic layer and ZnO nanorod arrays (ZnO-NAs) as electron acceptor. zno-nas 247-254 epoxide hydrolase 1 Homo sapiens 28-31 25280013-0 2015 "Imperfect" conjugated polymer nanoparticles from MEH-PPV for bioimaging and Fe(III) sensing. Polymers 23-30 epoxide hydrolase 1 Homo sapiens 50-53 25280013-0 2015 "Imperfect" conjugated polymer nanoparticles from MEH-PPV for bioimaging and Fe(III) sensing. ferric sulfate 77-84 epoxide hydrolase 1 Homo sapiens 50-53 25280013-1 2015 A simple and effective method was reported for the preparation from MEH-PPV of conjugated polymer nanoparticles (Pdots) that are water-soluble and well dispersed. Polymers 90-97 epoxide hydrolase 1 Homo sapiens 68-71 25280013-1 2015 A simple and effective method was reported for the preparation from MEH-PPV of conjugated polymer nanoparticles (Pdots) that are water-soluble and well dispersed. Water 129-134 epoxide hydrolase 1 Homo sapiens 68-71 25928072-4 2015 NIR-emitting polymer dots were prepared by encapsulating an NIR dye, silicon 2,3-naphthalocyanine bis(trihexylsilyloxide) (NIR775), into a matrix of polymer dots, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV), using a nanoscale precipitation method. Polymers 13-20 epoxide hydrolase 1 Homo sapiens 222-225 25928072-4 2015 NIR-emitting polymer dots were prepared by encapsulating an NIR dye, silicon 2,3-naphthalocyanine bis(trihexylsilyloxide) (NIR775), into a matrix of polymer dots, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV), using a nanoscale precipitation method. Silicon 2,3-naphthalocyanine bis(trihexylsilyloxide) 69-121 epoxide hydrolase 1 Homo sapiens 222-225 25999707-0 2015 Effect of N-acetylcysteine in COPD patients with different microsomal epoxide hydrolase genotypes. Acetylcysteine 10-26 epoxide hydrolase 1 Homo sapiens 59-87 25992604-2 2015 Microsomal epoxide hydrolase (mEH) is a bifunctional protein that plays a central role in the metabolism of numerous xenobiotics as well as mediating the sodium-dependent transport of bile acids into hepatocytes. Bile Acids and Salts 184-194 epoxide hydrolase 1 Homo sapiens 0-28 25992604-5 2015 Studies also identified heterozygous mutations in human EPHX1 that resulted in a 95% decrease in mEH expression levels which was associated with a decrease in bile acid transport and severe hypercholanemia. Bile Acids and Salts 159-168 epoxide hydrolase 1 Homo sapiens 56-61 25992604-6 2015 In the present investigation we demonstrate that EPHX1 transcription is significantly inhibited by two heterozygous mutations observed in the Old Order Amish population that present numerous hypercholanemic subjects in the absence of liver damage suggesting a defect in bile acid transport into the hepatocyte. Bile Acids and Salts 270-279 epoxide hydrolase 1 Homo sapiens 49-54 25992604-7 2015 The identity of the regulatory proteins binding to these sites, established using biotinylated oligonucleotides in conjunction with mass spectrometry was shown to be poly(ADP-ribose)polymerase-1 (PARP-1) bound to the EPHX1 proximal promoter and a linker histone complex, H1.2/Aly, bound to a regulatory intron 1 site. Oligonucleotides 95-111 epoxide hydrolase 1 Homo sapiens 217-222 25992604-2 2015 Microsomal epoxide hydrolase (mEH) is a bifunctional protein that plays a central role in the metabolism of numerous xenobiotics as well as mediating the sodium-dependent transport of bile acids into hepatocytes. Sodium 154-160 epoxide hydrolase 1 Homo sapiens 0-28 25999707-3 2015 The purpose of this study was to evaluate whether different EPHX1 enzyme activity is related to differential therapeutic effects of treatment with NAC in COPD. Acetylcysteine 147-150 epoxide hydrolase 1 Homo sapiens 60-65 25999707-10 2015 CONCLUSION: NAC treatment in COPD patients with extremely slow/slow EPHX1 enzyme activity improves FEV1 and the SGRQ symptom score, especially in those with mild-to-moderate COPD, and polymorphism in the EPHX1 gene may have a significant role in differential responses to treatment with NAC in patients with COPD. Acetylcysteine 12-15 epoxide hydrolase 1 Homo sapiens 68-73 25999707-10 2015 CONCLUSION: NAC treatment in COPD patients with extremely slow/slow EPHX1 enzyme activity improves FEV1 and the SGRQ symptom score, especially in those with mild-to-moderate COPD, and polymorphism in the EPHX1 gene may have a significant role in differential responses to treatment with NAC in patients with COPD. Acetylcysteine 12-15 epoxide hydrolase 1 Homo sapiens 204-209 25999707-10 2015 CONCLUSION: NAC treatment in COPD patients with extremely slow/slow EPHX1 enzyme activity improves FEV1 and the SGRQ symptom score, especially in those with mild-to-moderate COPD, and polymorphism in the EPHX1 gene may have a significant role in differential responses to treatment with NAC in patients with COPD. Acetylcysteine 287-290 epoxide hydrolase 1 Homo sapiens 204-209 25562543-2 2015 The aim of this work was to investigate the effects of polymorphic genes CYP2E1, EPHX1, GSTT1, and GSTM1 on the urinary concentrations of the styrene metabolites mandelic acid (MA), phenylglyoxylic acid (PGA) and on the concentration ratios between (MA+PGA) and urinary styrene (U-Sty) and airborne styrene (A-Sty), in 30 workers from two fiberglass-reinforced plastic manufacturing plants and 26 unexposed controls. Styrene 142-149 epoxide hydrolase 1 Homo sapiens 81-86 25966185-2 2015 Previous studies have suggested conflicting results regarding the association between Tyr113His and His139Arg microsomal epoxide hydrolase (mEH) gene polymorphisms and risk of breast carcinoma. tyr113his 86-95 epoxide hydrolase 1 Homo sapiens 110-138 25923690-5 2015 Overall, the pooled results indicated that the EPHX1 Tyr113His polymorphism was significantly associated with increased HNC risk (Tyr/His vs. Tyr/Tyr, OR = 1.26, 95%1.02-1.57;His/His+ Tyr/His vs. Tyr/Tyr, OR = 1.29, 95% I = 1.03-1.61). Tyrosine 53-56 epoxide hydrolase 1 Homo sapiens 47-52 25923690-5 2015 Overall, the pooled results indicated that the EPHX1 Tyr113His polymorphism was significantly associated with increased HNC risk (Tyr/His vs. Tyr/Tyr, OR = 1.26, 95%1.02-1.57;His/His+ Tyr/His vs. Tyr/Tyr, OR = 1.29, 95% I = 1.03-1.61). Histidine 59-62 epoxide hydrolase 1 Homo sapiens 47-52 25923690-5 2015 Overall, the pooled results indicated that the EPHX1 Tyr113His polymorphism was significantly associated with increased HNC risk (Tyr/His vs. Tyr/Tyr, OR = 1.26, 95%1.02-1.57;His/His+ Tyr/His vs. Tyr/Tyr, OR = 1.29, 95% I = 1.03-1.61). Tyrosine 130-133 epoxide hydrolase 1 Homo sapiens 47-52 25923690-5 2015 Overall, the pooled results indicated that the EPHX1 Tyr113His polymorphism was significantly associated with increased HNC risk (Tyr/His vs. Tyr/Tyr, OR = 1.26, 95%1.02-1.57;His/His+ Tyr/His vs. Tyr/Tyr, OR = 1.29, 95% I = 1.03-1.61). Tyrosine 130-133 epoxide hydrolase 1 Homo sapiens 47-52 25923690-5 2015 Overall, the pooled results indicated that the EPHX1 Tyr113His polymorphism was significantly associated with increased HNC risk (Tyr/His vs. Tyr/Tyr, OR = 1.26, 95%1.02-1.57;His/His+ Tyr/His vs. Tyr/Tyr, OR = 1.29, 95% I = 1.03-1.61). Histidine 134-137 epoxide hydrolase 1 Homo sapiens 47-52 25923690-5 2015 Overall, the pooled results indicated that the EPHX1 Tyr113His polymorphism was significantly associated with increased HNC risk (Tyr/His vs. Tyr/Tyr, OR = 1.26, 95%1.02-1.57;His/His+ Tyr/His vs. Tyr/Tyr, OR = 1.29, 95% I = 1.03-1.61). Histidine 134-137 epoxide hydrolase 1 Homo sapiens 47-52 25923690-5 2015 Overall, the pooled results indicated that the EPHX1 Tyr113His polymorphism was significantly associated with increased HNC risk (Tyr/His vs. Tyr/Tyr, OR = 1.26, 95%1.02-1.57;His/His+ Tyr/His vs. Tyr/Tyr, OR = 1.29, 95% I = 1.03-1.61). Tyrosine 130-133 epoxide hydrolase 1 Homo sapiens 47-52 25923690-5 2015 Overall, the pooled results indicated that the EPHX1 Tyr113His polymorphism was significantly associated with increased HNC risk (Tyr/His vs. Tyr/Tyr, OR = 1.26, 95%1.02-1.57;His/His+ Tyr/His vs. Tyr/Tyr, OR = 1.29, 95% I = 1.03-1.61). Histidine 134-137 epoxide hydrolase 1 Homo sapiens 47-52 25923690-5 2015 Overall, the pooled results indicated that the EPHX1 Tyr113His polymorphism was significantly associated with increased HNC risk (Tyr/His vs. Tyr/Tyr, OR = 1.26, 95%1.02-1.57;His/His+ Tyr/His vs. Tyr/Tyr, OR = 1.29, 95% I = 1.03-1.61). Tyrosine 130-133 epoxide hydrolase 1 Homo sapiens 47-52 25923690-5 2015 Overall, the pooled results indicated that the EPHX1 Tyr113His polymorphism was significantly associated with increased HNC risk (Tyr/His vs. Tyr/Tyr, OR = 1.26, 95%1.02-1.57;His/His+ Tyr/His vs. Tyr/Tyr, OR = 1.29, 95% I = 1.03-1.61). Tyrosine 130-133 epoxide hydrolase 1 Homo sapiens 47-52 25562543-5 2015 A reduction was also detected, in the same group, in subjects carrying the slow allele EPHX1 (codon 113), through the lowering of (MA+PGA)/urinary styrene concentration ratio. ma+pga 131-137 epoxide hydrolase 1 Homo sapiens 87-92 25562543-5 2015 A reduction was also detected, in the same group, in subjects carrying the slow allele EPHX1 (codon 113), through the lowering of (MA+PGA)/urinary styrene concentration ratio. Styrene 147-154 epoxide hydrolase 1 Homo sapiens 87-92 25562543-2 2015 The aim of this work was to investigate the effects of polymorphic genes CYP2E1, EPHX1, GSTT1, and GSTM1 on the urinary concentrations of the styrene metabolites mandelic acid (MA), phenylglyoxylic acid (PGA) and on the concentration ratios between (MA+PGA) and urinary styrene (U-Sty) and airborne styrene (A-Sty), in 30 workers from two fiberglass-reinforced plastic manufacturing plants and 26 unexposed controls. mandelic acid 162-175 epoxide hydrolase 1 Homo sapiens 81-86 26295053-8 2015 In conclusion, GSTs, EPHX1, and XPD are potential genetic factors for arsenic-induced skin cancers. Arsenic 70-77 epoxide hydrolase 1 Homo sapiens 21-26 25714851-1 2015 The microsomal epoxide hydrolase 1 (EPHX1) Tyr113His and His139Arg polymorphisms have been reported to be associated with esophageal cancer (EC) risk, yet the results of these previous results have been inconsistent or controversial. tyr113his 43-52 epoxide hydrolase 1 Homo sapiens 36-41 25714851-2 2015 The objective of this study was to explore whether the EPHX1 Tyr113His and His139Arg polymorphisms confer risk to EC. tyr113his 61-70 epoxide hydrolase 1 Homo sapiens 55-60 25714851-4 2015 The association between the EPHX1 Tyr113His and His139Arg polymorphisms and EC risk was pooled by odds ratios (ORs) together with their 95% confidence intervals (95%CIs). tyr113his 34-43 epoxide hydrolase 1 Homo sapiens 28-33 26065263-0 2015 [EPHX1 Tyr113His polymorphism contributes to hepatocellular carcinoma risk: evidfnce from a meta-analysis]. tyr113his 7-16 epoxide hydrolase 1 Homo sapiens 1-6 26065263-1 2015 To clarify the association between microsomal epoxide hydrolase gene (EPHX1) Tyr113His polymorphism and hepatocellular carcinoma (HCC) risk, a meta-analysis was performed. tyr113his 77-86 epoxide hydrolase 1 Homo sapiens 35-63 26065263-1 2015 To clarify the association between microsomal epoxide hydrolase gene (EPHX1) Tyr113His polymorphism and hepatocellular carcinoma (HCC) risk, a meta-analysis was performed. tyr113his 77-86 epoxide hydrolase 1 Homo sapiens 70-75 26065263-2 2015 Overall, EPHX1 Tyr113His polymorphism was associated with increased risk of HCC. tyr113his 15-24 epoxide hydrolase 1 Homo sapiens 9-14 26065263-6 2015 This meta-analysis suggests that EPHX1 Tyr113His polymorphism contributes to HCC risk. tyr113his 39-48 epoxide hydrolase 1 Homo sapiens 33-38 25579988-2 2015 We verify that the employed semiconducting polymer, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV), controls the self-assembly of CH3NH3PbI3 (MAPbI3) crystalline domains and favors the deposition of a very smooth and homogenous layer in one straightforward step. Polymers 43-50 epoxide hydrolase 1 Homo sapiens 111-114 25579988-2 2015 We verify that the employed semiconducting polymer, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV), controls the self-assembly of CH3NH3PbI3 (MAPbI3) crystalline domains and favors the deposition of a very smooth and homogenous layer in one straightforward step. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 52-109 epoxide hydrolase 1 Homo sapiens 111-114 25579988-2 2015 We verify that the employed semiconducting polymer, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV), controls the self-assembly of CH3NH3PbI3 (MAPbI3) crystalline domains and favors the deposition of a very smooth and homogenous layer in one straightforward step. ch3nh3pbi3 151-161 epoxide hydrolase 1 Homo sapiens 111-114 25574936-0 2015 PFO-DBT:MEH-PPV:PC71BM ternary blend assisted platform as a photodetector. perfluorooctane sulfonic acid 0-3 epoxide hydrolase 1 Homo sapiens 8-11 25574936-1 2015 We present a ternary blend-based bulk heterojunction ITO/PEDOT:PSS/PFO-DBT: MEH-PPV:PC71BM/LiF/Al photodetector. perfluorooctane sulfonic acid 67-70 epoxide hydrolase 1 Homo sapiens 76-79 25574936-1 2015 We present a ternary blend-based bulk heterojunction ITO/PEDOT:PSS/PFO-DBT: MEH-PPV:PC71BM/LiF/Al photodetector. di-n-butyltin 71-74 epoxide hydrolase 1 Homo sapiens 76-79 26295053-2 2015 We hypothesized that glutathione S-transferase (GST M1, T1, and P1), reactive oxygen species (ROS) related metabolic genes (NQO1, EPHX1, and HO-1), and DNA repair genes (XRCC1, XPD, hOGG1, and ATM) together may play a role in arsenic-induced skin carcinogenesis. Reactive Oxygen Species 94-97 epoxide hydrolase 1 Homo sapiens 130-135 26314341-3 2015 RESULTS: Both univariate and multiple regression analyses revealed that carriers of the SCN1A IVS5-91G>A or EPHX1 c.337T>C allele tended to require a higher CBZ dose and a lower CBZ natural logarithmic concentration-dose ratio (lnCDR) than noncarriers (p < 0.05). Carbamazepine 163-166 epoxide hydrolase 1 Homo sapiens 111-116 25629049-0 2015 Influence of two common polymorphisms in the EPHX1 gene on warfarin maintenance dosage: a meta-analysis. Warfarin 59-67 epoxide hydrolase 1 Homo sapiens 45-50 25629049-1 2015 We conducted a meta-analysis to investigate the influence of two common single nucleotide polymorphisms (SNPs) (rs2292566 G>A and rs4653436 A>G) in the EPHX1 gene on warfarin maintenance dosages. Warfarin 172-180 epoxide hydrolase 1 Homo sapiens 158-163 25629049-6 2015 Meta-analysis results illustrated that EPHX1 rs2292566 G>A polymorphism might be strongly correlated with a higher maintenance dose of warfarin. Warfarin 138-146 epoxide hydrolase 1 Homo sapiens 39-44 25629049-8 2015 A further subgroup analysis based on stratification by ethnicity indicated that EPHX1 rs2292566 G>A polymorphism was positively correlated with warfarin maintenance dosage among Caucasians, but not Asians. Warfarin 147-155 epoxide hydrolase 1 Homo sapiens 80-85 25629049-10 2015 Our meta-analysis provides robust and unambiguous evidence that EPHX1 rs2292566 polymorphism may affect the maintenance dose of warfarin in Caucasians. Warfarin 128-136 epoxide hydrolase 1 Homo sapiens 64-69 26314341-3 2015 RESULTS: Both univariate and multiple regression analyses revealed that carriers of the SCN1A IVS5-91G>A or EPHX1 c.337T>C allele tended to require a higher CBZ dose and a lower CBZ natural logarithmic concentration-dose ratio (lnCDR) than noncarriers (p < 0.05). Carbamazepine 184-187 epoxide hydrolase 1 Homo sapiens 111-116 24958911-0 2014 A novel activity of microsomal epoxide hydrolase: metabolism of the endocannabinoid 2-arachidonoylglycerol. Endocannabinoids 68-83 epoxide hydrolase 1 Homo sapiens 20-48 24958911-0 2014 A novel activity of microsomal epoxide hydrolase: metabolism of the endocannabinoid 2-arachidonoylglycerol. glyceryl 2-arachidonate 84-106 epoxide hydrolase 1 Homo sapiens 20-48 24958911-8 2014 These results demonstrate that 2-AG is an endogenous substrate for EPHX1, a potential role of EPHX1 in the endocannabinoid signaling and a new AA biosynthetic pathway. glyceryl 2-arachidonate 31-35 epoxide hydrolase 1 Homo sapiens 67-72 24958911-3 2014 In this study, we present evidence that EPHX1 metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol. Endocannabinoids 71-86 epoxide hydrolase 1 Homo sapiens 40-45 24958911-3 2014 In this study, we present evidence that EPHX1 metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol. glyceryl 2-arachidonate 87-109 epoxide hydrolase 1 Homo sapiens 40-45 24958911-3 2014 In this study, we present evidence that EPHX1 metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol. glyceryl 2-arachidonate 111-115 epoxide hydrolase 1 Homo sapiens 40-45 24958911-3 2014 In this study, we present evidence that EPHX1 metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol. Arachidonic Acid 125-141 epoxide hydrolase 1 Homo sapiens 40-45 24958911-3 2014 In this study, we present evidence that EPHX1 metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol. Glycerol 101-109 epoxide hydrolase 1 Homo sapiens 40-45 24958911-4 2014 The EPHX1 metabolism of 2-AG was demonstrated using commercially available EPHX1 microsomes as well as PC-3 cells overexpressing EPHX1. glyceryl 2-arachidonate 24-28 epoxide hydrolase 1 Homo sapiens 4-9 24958911-4 2014 The EPHX1 metabolism of 2-AG was demonstrated using commercially available EPHX1 microsomes as well as PC-3 cells overexpressing EPHX1. glyceryl 2-arachidonate 24-28 epoxide hydrolase 1 Homo sapiens 75-80 24958911-4 2014 The EPHX1 metabolism of 2-AG was demonstrated using commercially available EPHX1 microsomes as well as PC-3 cells overexpressing EPHX1. glyceryl 2-arachidonate 24-28 epoxide hydrolase 1 Homo sapiens 75-80 24958911-6 2014 A selective EPHX1 inhibitor, 10-hydroxystearamide, inhibited 2-AG metabolism and hydrolysis of a well-known EPHX1 substrate, cis-stilbene oxide. 10-Hydroxystearamide 29-49 epoxide hydrolase 1 Homo sapiens 12-17 24958911-6 2014 A selective EPHX1 inhibitor, 10-hydroxystearamide, inhibited 2-AG metabolism and hydrolysis of a well-known EPHX1 substrate, cis-stilbene oxide. 10-Hydroxystearamide 29-49 epoxide hydrolase 1 Homo sapiens 108-113 24958911-6 2014 A selective EPHX1 inhibitor, 10-hydroxystearamide, inhibited 2-AG metabolism and hydrolysis of a well-known EPHX1 substrate, cis-stilbene oxide. glyceryl 2-arachidonate 61-65 epoxide hydrolase 1 Homo sapiens 12-17 24958911-6 2014 A selective EPHX1 inhibitor, 10-hydroxystearamide, inhibited 2-AG metabolism and hydrolysis of a well-known EPHX1 substrate, cis-stilbene oxide. stilbene oxide 125-143 epoxide hydrolase 1 Homo sapiens 12-17 24958911-6 2014 A selective EPHX1 inhibitor, 10-hydroxystearamide, inhibited 2-AG metabolism and hydrolysis of a well-known EPHX1 substrate, cis-stilbene oxide. stilbene oxide 125-143 epoxide hydrolase 1 Homo sapiens 108-113 24958911-7 2014 Among the inhibitors studied, a serine hydrolase inhibitor, methoxy-arachidonyl fluorophosphate, was the most potent inhibitor of 2-AG metabolism by EPHX1 microsomes. methoxy-arachidonyl fluorophosphate 60-95 epoxide hydrolase 1 Homo sapiens 149-154 24958911-7 2014 Among the inhibitors studied, a serine hydrolase inhibitor, methoxy-arachidonyl fluorophosphate, was the most potent inhibitor of 2-AG metabolism by EPHX1 microsomes. glyceryl 2-arachidonate 130-134 epoxide hydrolase 1 Homo sapiens 149-154 24861996-0 2014 Association of ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms with the risk of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Chinese Han patients with epilepsy. Carbamazepine 95-108 epoxide hydrolase 1 Homo sapiens 30-35 25261893-1 2014 PURPOSE: Previous studies investigating the association between EPHX1 polymorphisms (Tyr113His and His139Arg) and cancer risk have yielded inconsistent results. tyr113his 85-94 epoxide hydrolase 1 Homo sapiens 64-69 25261893-8 2014 CONCLUSION: His/His genotype of EPHX1 Tyr113His polymorphism is a risk factor for developing caner for Asian and mixed population, while no evidence was found for the association between the EPHX1 His139Arg polymorphism and increased cancer risk. tyr113his 38-47 epoxide hydrolase 1 Homo sapiens 32-37 25222243-1 2014 The association between the microsomal epoxide hydrolase 1 gene (EPHX1) Tyr113His polymorphism and lung cancer and breast cancer risk has been reported in many recent studies, but there is no consensus among the results. tyr113his 72-81 epoxide hydrolase 1 Homo sapiens 65-70 25222243-2 2014 Thus, we examined the association between the EPHX1 Tyr113His polymorphism and lung cancer through a meta-analysis. tyr113his 52-61 epoxide hydrolase 1 Homo sapiens 46-51 25222243-8 2014 Our meta-analysis suggested that the EPHX1 Tyr113His polymorphism may be a risk factor for lung cancer in Asians, whereas it may be a decreased risk factor among Caucasians. tyr113his 43-52 epoxide hydrolase 1 Homo sapiens 37-42 24861996-4 2014 RESULTS: We observed statistically significant differences in EPHX1 c.337T>C polymorphisms between patients with CBZ-SJS/TEN and CBZ-tolerant controls in terms of allelic and genotypic frequencies (p = 0.011 and p = 0.007, respectively). Carbamazepine 116-119 epoxide hydrolase 1 Homo sapiens 62-67 24861996-4 2014 RESULTS: We observed statistically significant differences in EPHX1 c.337T>C polymorphisms between patients with CBZ-SJS/TEN and CBZ-tolerant controls in terms of allelic and genotypic frequencies (p = 0.011 and p = 0.007, respectively). Carbamazepine 132-135 epoxide hydrolase 1 Homo sapiens 62-67 24684587-0 2014 Evaporative assembly of MEH-PPV rings using mixed solvents at the air/water interface. Water 70-75 epoxide hydrolase 1 Homo sapiens 24-27 24861996-5 2014 The C allele and the C-G diplotype of EPHX1 may play important roles in increasing the risk of CBZ-SJS/TEN development (odds ratio [OR] 0.478, 95% confidence interval [CI] = 0.267-0.855, p = 0.011; OR = 0.213, 95% CI = 0.049-0.930, p = 0.025, respectively). Carbamazepine 95-98 epoxide hydrolase 1 Homo sapiens 38-43 24861996-8 2014 EPHX1 c.337T>C polymorphisms may contribute to the risk of severe CBZ-SJS/TEN by increasing the concentration of a CBZ metabolite, CBZ-10,11-epoxide, in patients with epilepsy. Carbamazepine 69-72 epoxide hydrolase 1 Homo sapiens 0-5 24861996-8 2014 EPHX1 c.337T>C polymorphisms may contribute to the risk of severe CBZ-SJS/TEN by increasing the concentration of a CBZ metabolite, CBZ-10,11-epoxide, in patients with epilepsy. Carbamazepine 118-121 epoxide hydrolase 1 Homo sapiens 0-5 24861996-8 2014 EPHX1 c.337T>C polymorphisms may contribute to the risk of severe CBZ-SJS/TEN by increasing the concentration of a CBZ metabolite, CBZ-10,11-epoxide, in patients with epilepsy. carbamazepine epoxide 134-151 epoxide hydrolase 1 Homo sapiens 0-5 24684587-2 2014 Here, we describe the self-assembly of a common conjugated polymer, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV), into ringlike structures via solvent evaporation on an air/water interface. Polymers 59-66 epoxide hydrolase 1 Homo sapiens 127-130 24684587-2 2014 Here, we describe the self-assembly of a common conjugated polymer, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV), into ringlike structures via solvent evaporation on an air/water interface. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 68-125 epoxide hydrolase 1 Homo sapiens 127-130 24758376-0 2014 Hepatitis B spliced protein (HBSP) promotes the carcinogenic effects of benzo [alpha] pyrene by interacting with microsomal epoxide hydrolase and enhancing its hydrolysis activity. benzo [alpha] pyrene 72-92 epoxide hydrolase 1 Homo sapiens 113-141 24684587-4 2014 The morphology of the MEH-PPV thin film at the air/water interface can be controlled by the spreading solvent. Water 51-56 epoxide hydrolase 1 Homo sapiens 22-25 24469582-9 2014 Current results indicate that multifunctional fluorene-based material FTC is a potential candidate for selective detection of Fe(3+) and as an effective electron injection layer to enhance the performance of MEH-PPV. fluorene 46-54 epoxide hydrolase 1 Homo sapiens 208-211 24684587-5 2014 By mixing solvents of varying spreading coefficients and evaporation rates, such as chloroform and chlorobenzene, MEH-PPV can be assembled into micrometer-sized ring structures. Chloroform 84-94 epoxide hydrolase 1 Homo sapiens 114-117 24684587-5 2014 By mixing solvents of varying spreading coefficients and evaporation rates, such as chloroform and chlorobenzene, MEH-PPV can be assembled into micrometer-sized ring structures. chlorobenzene 99-112 epoxide hydrolase 1 Homo sapiens 114-117 24817818-0 2014 Effects of EPHX1 and CYP3A4 polymorphisms on carbamazepine metabolism in epileptic patients. Carbamazepine 45-58 epoxide hydrolase 1 Homo sapiens 11-16 24817818-1 2014 BACKGROUND: The aim of this study was to investigate the effect of two genetic polymorphisms in the coding regions (exon 3 and exon 4) of the EPHX1 gene, ie, 337T>C and 416A>G, respectively, on the metabolism of carbamazepine (CBZ) 10,11-epoxide (the active metabolite of CBZ) by evaluating the variation in serum CBZ 10,11-epoxide levels 4 hours after administration of the drug. Carbamazepine 218-231 epoxide hydrolase 1 Homo sapiens 142-147 24817818-1 2014 BACKGROUND: The aim of this study was to investigate the effect of two genetic polymorphisms in the coding regions (exon 3 and exon 4) of the EPHX1 gene, ie, 337T>C and 416A>G, respectively, on the metabolism of carbamazepine (CBZ) 10,11-epoxide (the active metabolite of CBZ) by evaluating the variation in serum CBZ 10,11-epoxide levels 4 hours after administration of the drug. Carbamazepine 233-236 epoxide hydrolase 1 Homo sapiens 142-147 24817818-1 2014 BACKGROUND: The aim of this study was to investigate the effect of two genetic polymorphisms in the coding regions (exon 3 and exon 4) of the EPHX1 gene, ie, 337T>C and 416A>G, respectively, on the metabolism of carbamazepine (CBZ) 10,11-epoxide (the active metabolite of CBZ) by evaluating the variation in serum CBZ 10,11-epoxide levels 4 hours after administration of the drug. 10,11-epoxide 238-251 epoxide hydrolase 1 Homo sapiens 142-147 24817818-1 2014 BACKGROUND: The aim of this study was to investigate the effect of two genetic polymorphisms in the coding regions (exon 3 and exon 4) of the EPHX1 gene, ie, 337T>C and 416A>G, respectively, on the metabolism of carbamazepine (CBZ) 10,11-epoxide (the active metabolite of CBZ) by evaluating the variation in serum CBZ 10,11-epoxide levels 4 hours after administration of the drug. Carbamazepine 278-281 epoxide hydrolase 1 Homo sapiens 142-147 24817818-1 2014 BACKGROUND: The aim of this study was to investigate the effect of two genetic polymorphisms in the coding regions (exon 3 and exon 4) of the EPHX1 gene, ie, 337T>C and 416A>G, respectively, on the metabolism of carbamazepine (CBZ) 10,11-epoxide (the active metabolite of CBZ) by evaluating the variation in serum CBZ 10,11-epoxide levels 4 hours after administration of the drug. carbamazepine epoxide 320-337 epoxide hydrolase 1 Homo sapiens 142-147 24618928-1 2014 Both pendant and main chain conjugated MEH-PPV based polymers have been studied at the level of single chains using confocal and widefield fluorescence microscopy techniques. Polymers 53-61 epoxide hydrolase 1 Homo sapiens 39-42 24618928-4 2014 Surprisingly in polymers with a saturated backbone but containing the same pendant MEH-PPV oligomer on each repeating unit, intra-chain energy transfer to a single emitter is also apparent. Polymers 16-24 epoxide hydrolase 1 Homo sapiens 83-86 24618928-6 2014 Both main chain conjugated and pendant MEH-PPV polymers exhibit changes in orientation of the emission dipole during a fluorescence trajectory of many seconds, whereas a model MEH-PPV oligomer does not. Polymers 47-55 epoxide hydrolase 1 Homo sapiens 39-42 24618928-6 2014 Both main chain conjugated and pendant MEH-PPV polymers exhibit changes in orientation of the emission dipole during a fluorescence trajectory of many seconds, whereas a model MEH-PPV oligomer does not. Polymers 47-55 epoxide hydrolase 1 Homo sapiens 176-179 24618928-6 2014 Both main chain conjugated and pendant MEH-PPV polymers exhibit changes in orientation of the emission dipole during a fluorescence trajectory of many seconds, whereas a model MEH-PPV oligomer does not. dipole 103-109 epoxide hydrolase 1 Homo sapiens 39-42 24457425-1 2014 In this work, we report that the Ag-graphene composite (AGC) can effectively enhance the light harvesting and photoluminescence (PL) quenching efficiency of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene-vinylene] (MEH-PPV). ag-graphene 33-44 epoxide hydrolase 1 Homo sapiens 217-220 24457425-1 2014 In this work, we report that the Ag-graphene composite (AGC) can effectively enhance the light harvesting and photoluminescence (PL) quenching efficiency of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene-vinylene] (MEH-PPV). poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene-vinylene] 157-215 epoxide hydrolase 1 Homo sapiens 217-220 26580196-0 2014 Electronic Excited States in Amorphous MEH-PPV Polymers from Large-Scale First Principles Calculations. Polymers 47-55 epoxide hydrolase 1 Homo sapiens 39-42 26580196-2 2014 We inferred an average conjugation length of ~5-7 monomers for lowest vertical excitations of amorphous MEH-PPV at room temperature and verified that the normal definition of a chromophore in a polymer based on purely geometric "conjugation breaks" is not always valid in amorphous polymers and a rigorous definition can be only on the basis of the evaluation of the polymer excited state wave function. Polymers 194-201 epoxide hydrolase 1 Homo sapiens 104-107 25495409-2 2014 MATERIALS & METHODS: For 210 epileptic patients treated with CBZ as monotherapy, nine SNPs in candidate genes ABCB1, CYP3A4, CYP3A5, POR and EPHX1 were analyzed by PCR-RFLP or direct sequencing. Adenosine Monophosphate 11-14 epoxide hydrolase 1 Homo sapiens 145-150 24505354-9 2014 In addition, knockdown and overexpression experiments in KGN cells showed that EPHX1 can regulate estradiol concentrations, and this indicates a role for EPHX1 in steroidogenesis. Estradiol 98-107 epoxide hydrolase 1 Homo sapiens 79-84 24309146-2 2014 To evaluate the selectivity of sEH inhibition, the inhibition of microsomal epoxide hydrolase (mEH), which plays a critical role in detoxification of toxic epoxides, was determined using human liver microsomes. Epoxy Compounds 156-164 epoxide hydrolase 1 Homo sapiens 65-93 24092646-0 2014 Is there a role for MDR1, EPHX1 and protein Z gene variants in modulation of warfarin dosage? Warfarin 77-85 epoxide hydrolase 1 Homo sapiens 26-31 24092646-4 2014 Genes encoding drug transporters, such as human multidrug resistance (MDR1), as well as epoxide hydrolase 1 (EPHX1), which is a putative subunit of the vitamin K epoxide reductase, and Protein Z (PZ), which is a vitamin K-dependent plasma glycoprotein, are among those candidate genes. Vitamin K 152-161 epoxide hydrolase 1 Homo sapiens 88-107 24092646-4 2014 Genes encoding drug transporters, such as human multidrug resistance (MDR1), as well as epoxide hydrolase 1 (EPHX1), which is a putative subunit of the vitamin K epoxide reductase, and Protein Z (PZ), which is a vitamin K-dependent plasma glycoprotein, are among those candidate genes. Vitamin K 152-161 epoxide hydrolase 1 Homo sapiens 109-114 24092646-5 2014 OBJECTIVE: The purpose of this study was to investigate the contribution of MDR1 C3435T, EPHX1 H139R and PZ A-13G gene polymorphisms in warfarin dose variation in a cohort of the Egyptian population. Warfarin 136-144 epoxide hydrolase 1 Homo sapiens 89-94 24092646-11 2014 However, when these single nucleotide polymorphisms (SNPs) were combined, MDR1 TT/EPHX1 RH,RR/PZ AA subjects showed statistically significant increase in warfarin dose/week when compared with MDR1 CC/EPHX1 RH,RR/PZ AA subjects [median (25th-75th percentiles): 49.0 (42.0-59.5) vs. 35.0 (24.5-42.0) mg/week, respectively] (p = 0.014). Warfarin 154-162 epoxide hydrolase 1 Homo sapiens 82-87 24092646-11 2014 However, when these single nucleotide polymorphisms (SNPs) were combined, MDR1 TT/EPHX1 RH,RR/PZ AA subjects showed statistically significant increase in warfarin dose/week when compared with MDR1 CC/EPHX1 RH,RR/PZ AA subjects [median (25th-75th percentiles): 49.0 (42.0-59.5) vs. 35.0 (24.5-42.0) mg/week, respectively] (p = 0.014). Warfarin 154-162 epoxide hydrolase 1 Homo sapiens 200-205 24092646-12 2014 In contrast, in the presence of wild-type EPHX1 HH, there was a decrease in warfarin dose/week in MDR1 TT subjects when compared with CT and CC subjects [median (25th-75th percentiles): 22.0 (17.5-30.6), 42.0 (35.0-49.0) and 42.0 (28.0-54.3) mg/week, respectively] (p = 0.005 and 0.030, respectively). Warfarin 76-84 epoxide hydrolase 1 Homo sapiens 42-47 24092646-20 2014 CONCLUSION: Warfarin dose/week was significantly influenced by the combined MDR1 C3435T and EPHX1 H139R gene polymorphism since no polymorphism of PZ A-13G SNP was detected in our studied Egyptian population. Warfarin 12-20 epoxide hydrolase 1 Homo sapiens 92-97 24406279-5 2014 On the other hand, in order to explain the differences in the clinical response to CBZ, genetic polymorphisms in phase I (CYP3A4, CYP3A5 and EPHX1) and phase II (UGT2B7) metabolising enzymes have been assessed; additionally, the influence of transporters (ABCB1 and ABCC2), receptors (PXR) and other drug targets (voltage- gated Na+ channels) in CBZ clinical response has been evaluated. Carbamazepine 83-86 epoxide hydrolase 1 Homo sapiens 141-146 25638374-1 2014 OBJECTIVES: Cytochrome P450 (CYP) 1A1 located in the membrane of endoplasmic reticulum is the most important enzyme in both activation and detoxification of carcinogenic benzo[a]pyrene (BaP), in combination with microsomal epoxide hydrolase (mEH). pyrene 178-184 epoxide hydrolase 1 Homo sapiens 212-240 25638374-1 2014 OBJECTIVES: Cytochrome P450 (CYP) 1A1 located in the membrane of endoplasmic reticulum is the most important enzyme in both activation and detoxification of carcinogenic benzo[a]pyrene (BaP), in combination with microsomal epoxide hydrolase (mEH). Benzo(a)pyrene 186-189 epoxide hydrolase 1 Homo sapiens 212-240 24615030-0 2014 EPHX1 Tyr113His and His139Arg polymorphisms in esophageal cancer risk: a meta-analysis. tyr113his 6-15 epoxide hydrolase 1 Homo sapiens 0-5 24615030-1 2014 Microsomal epoxide hydrolase 1 (EPHX1) is an important biological phase II metabolic enzyme that is extensively involved in the metabolism of diverse environmental carcinogens such as polycyclic aromatic hydrocarbons and heterocyclic amines. Polycyclic Aromatic Hydrocarbons 184-216 epoxide hydrolase 1 Homo sapiens 32-37 24615030-1 2014 Microsomal epoxide hydrolase 1 (EPHX1) is an important biological phase II metabolic enzyme that is extensively involved in the metabolism of diverse environmental carcinogens such as polycyclic aromatic hydrocarbons and heterocyclic amines. Amines 234-240 epoxide hydrolase 1 Homo sapiens 32-37 24615030-2 2014 Many articles have reported the association between EPHX1 (Tyr113His and His139Arg) polymorphisms and esophageal cancer risk, but the results are controversial. tyr113his 59-68 epoxide hydrolase 1 Homo sapiens 52-57 24615030-3 2014 This study aimed to identify the association between EPHX1 (Tyr113His and His139Arg) polymorphisms and esophageal cancer risk by meta-analysis. tyr113his 60-69 epoxide hydrolase 1 Homo sapiens 53-58 25495409-2 2014 MATERIALS & METHODS: For 210 epileptic patients treated with CBZ as monotherapy, nine SNPs in candidate genes ABCB1, CYP3A4, CYP3A5, POR and EPHX1 were analyzed by PCR-RFLP or direct sequencing. Carbamazepine 65-68 epoxide hydrolase 1 Homo sapiens 145-150 25495409-7 2014 The EPHX1 c.416A>G and c.128G>C variants were significantly associated with CBZD:CBZE ratio. carbamazepine-10,11-dihydrodiol 82-86 epoxide hydrolase 1 Homo sapiens 4-9 24125961-4 2013 Patients with the variant EPHX1 c.416A>G genotypes had higher adjusted plasma CBZ concentrations compared to those with the wild type genotype (P<0.05). Carbamazepine 81-84 epoxide hydrolase 1 Homo sapiens 26-31 24096572-1 2013 The authors demonstrate a smart and versatile approach for preparing multi-spectral conjugated polymers from a commercial precursor MEH-PPV without tedious synthetic modification. Polymers 95-103 epoxide hydrolase 1 Homo sapiens 132-135 24125961-7 2013 These results suggest that the EPHX1 c.416A>G polymorphism affects CBZ metabolism in Chinese patients with epilepsy. Carbamazepine 70-73 epoxide hydrolase 1 Homo sapiens 31-36 24260161-5 2013 RESULTS: We found positive interaction odds ratios (ORs) for both maternal and paternal smoking during pregnancy, EPHX1 H139R, and childhood brain tumors (P(interaction) = 0.02; 0.10), such that children with the high-risk (greater PAH activation) genotype were at a higher risk of brain tumors relative to children with the low-risk genotype when exposed to tobacco smoke during pregnancy. Polycyclic Aromatic Hydrocarbons 232-235 epoxide hydrolase 1 Homo sapiens 114-119 24070307-0 2013 The red-phase of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV): a disordered HJ-aggregate. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 17-74 epoxide hydrolase 1 Homo sapiens 76-79 24144347-3 2013 Moreover, we found that a low doping of spin radicals in polymer MEH-PPV causes a significant change on the MFC signal: an amplitude increase and a line-shape narrowing under light illumination at room temperature. Polymers 57-64 epoxide hydrolase 1 Homo sapiens 65-68 24099661-1 2013 Blended poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-(1,4-benzo-{2,1",3}-thiadiazole)] (PFBT)/poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) conjugated polymer nanoparticles were prepared and characterized by conventional and single-particle fluorescence spectroscopy. poly((9,9-dioctylfluorenyl-2,7-diyl)-co-(1,4-benzo-(2,1',3)-thiadiazole)) 83-87 epoxide hydrolase 1 Homo sapiens 148-151 24555346-4 2013 And the intensity of near ultraviolet emission from ZnO is stronger than that of the orange-red emission belonging to MEH-PPV. Zinc Oxide 52-55 epoxide hydrolase 1 Homo sapiens 118-121 24002399-0 2013 Steady state and time resolved spectroscopic study of C-dots-MEH-PPV polymer nanoparticles composites. c-dots 54-60 epoxide hydrolase 1 Homo sapiens 61-64 24002399-4 2013 C-dots-MEH-PPV polymer nanoparticles composites are formed by electrostatic interaction between these particles. c-dots 0-6 epoxide hydrolase 1 Homo sapiens 7-10 24002399-4 2013 C-dots-MEH-PPV polymer nanoparticles composites are formed by electrostatic interaction between these particles. Polymers 15-22 epoxide hydrolase 1 Homo sapiens 7-10 23714182-1 2013 Microsomal epoxide hydrolase (mEH) is a bifunctional protein that plays a central role in the metabolism of numerous xenobiotics as well as mediating the sodium-dependent transport of bile acids into hepatocytes where they are involved in cholesterol excretion and metabolism, lipid digestion and regulating numerous signaling pathways. Sodium 154-160 epoxide hydrolase 1 Homo sapiens 0-28 23714182-1 2013 Microsomal epoxide hydrolase (mEH) is a bifunctional protein that plays a central role in the metabolism of numerous xenobiotics as well as mediating the sodium-dependent transport of bile acids into hepatocytes where they are involved in cholesterol excretion and metabolism, lipid digestion and regulating numerous signaling pathways. Bile Acids and Salts 184-194 epoxide hydrolase 1 Homo sapiens 0-28 23714182-4 2013 Bile acids, which inhibit the expression of HNF-4alpha also decrease the expression of EPHX1. Bile Acids and Salts 0-10 epoxide hydrolase 1 Homo sapiens 87-92 24555346-0 2013 [Tunneling electroluminescence of the ZnO nanorods/MEH-PPV heterojunction devices]. Zinc Oxide 38-41 epoxide hydrolase 1 Homo sapiens 51-54 24555346-3 2013 When a reverse bias exceeding 17 volts was applied to the ZnO-NRs/ MEH-PPV heterojunction, both emissions of ZnO and MEH-PPV were detected. Zinc Oxide 58-61 epoxide hydrolase 1 Homo sapiens 67-70 24555346-3 2013 When a reverse bias exceeding 17 volts was applied to the ZnO-NRs/ MEH-PPV heterojunction, both emissions of ZnO and MEH-PPV were detected. Zinc Oxide 58-61 epoxide hydrolase 1 Homo sapiens 117-120 24555346-3 2013 When a reverse bias exceeding 17 volts was applied to the ZnO-NRs/ MEH-PPV heterojunction, both emissions of ZnO and MEH-PPV were detected. Zinc Oxide 109-112 epoxide hydrolase 1 Homo sapiens 67-70 24070307-1 2013 The ratio of the 0-0 to 0-1 peak intensities in the photoluminescence (PL) spectrum of red-phase poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene], better known as MEH-PPV, is significantly enhanced relative to the disordered blue-phase and is practically temperature independent in the range from T = 5 K to 180 K. The PL lifetime is similarly temperature independent. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene 97-153 epoxide hydrolase 1 Homo sapiens 172-175 24070307-8 2013 Interestingly, interchain interactions lead only to about a 30% drop in the PL ratio, suggesting that the MEH-PPV pi-stacks--and strongly disordered HJ-aggregates in general--can masquerade as single (elongated) chains. pl 76-78 epoxide hydrolase 1 Homo sapiens 106-109 24015753-1 2013 A straight synthetic route to fabricate hybrid nanocomposite films of well-dispersed CdS nanocrystals (NCs) in poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV) is reported. poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] 111-171 epoxide hydrolase 1 Homo sapiens 173-176 24015753-4 2013 Photoluminescence spectroscopy measurements performed on CdS/MEH-PPV nanocomposites show that CdS photoluminescence peaks are totally quenched inside MEH-PPV, if compared to CdS/PMMA nanocomposites, as expected due to overlapping of the polymer absorption and CdS emission spectra. Polymethyl Methacrylate 178-182 epoxide hydrolase 1 Homo sapiens 61-64 24015753-4 2013 Photoluminescence spectroscopy measurements performed on CdS/MEH-PPV nanocomposites show that CdS photoluminescence peaks are totally quenched inside MEH-PPV, if compared to CdS/PMMA nanocomposites, as expected due to overlapping of the polymer absorption and CdS emission spectra. Polymers 237-244 epoxide hydrolase 1 Homo sapiens 61-64 23683960-2 2013 Stable aqueous CPN dispersion of poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylvinylene)(MEH-PPV) and regioregular poly(3-octylthiophene)(rr-P3OT) are prepared via reprecipitation technique. cpn 15-18 epoxide hydrolase 1 Homo sapiens 89-92 23867956-4 2013 Both 1-OHP concentration and urinary mutagenicity tested by TA98+S9 were significantly higher in individuals with EPHX1 (exon 4) Arg/Arg genotype than in individuals with other genotype. Oxaliplatin 5-10 epoxide hydrolase 1 Homo sapiens 114-119 23867956-4 2013 Both 1-OHP concentration and urinary mutagenicity tested by TA98+S9 were significantly higher in individuals with EPHX1 (exon 4) Arg/Arg genotype than in individuals with other genotype. Arginine 129-132 epoxide hydrolase 1 Homo sapiens 114-119 23867956-4 2013 Both 1-OHP concentration and urinary mutagenicity tested by TA98+S9 were significantly higher in individuals with EPHX1 (exon 4) Arg/Arg genotype than in individuals with other genotype. Arginine 133-136 epoxide hydrolase 1 Homo sapiens 114-119 24084344-0 2013 Cytogenetic damage in Turkish coke oven workers exposed to polycyclic aromatic hydrocarbons: Association with CYP1A1, CYP1B1, EPHX1, GSTM1, GSTT1, and GSTP1 gene polymorphisms. Polycyclic Aromatic Hydrocarbons 59-91 epoxide hydrolase 1 Homo sapiens 126-131 23648357-11 2013 RESULTS: The EPHX1 low activity diplotype consistently imparts greater susceptibility to bronchitis from second-hand tobacco smoke, polyclic aromatic hydrocarbons (PAH) and PM2.5. polyclic aromatic hydrocarbons 132-162 epoxide hydrolase 1 Homo sapiens 13-18 23648357-11 2013 RESULTS: The EPHX1 low activity diplotype consistently imparts greater susceptibility to bronchitis from second-hand tobacco smoke, polyclic aromatic hydrocarbons (PAH) and PM2.5. p-Aminohippuric Acid 164-167 epoxide hydrolase 1 Homo sapiens 13-18 23683960-2 2013 Stable aqueous CPN dispersion of poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylvinylene)(MEH-PPV) and regioregular poly(3-octylthiophene)(rr-P3OT) are prepared via reprecipitation technique. poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylvinylene) 33-88 epoxide hydrolase 1 Homo sapiens 89-92 23683960-7 2013 The preparation of MEH-PPV nanoparticles from DCM solution provides average size of about 127 nm. Methylene Chloride 46-49 epoxide hydrolase 1 Homo sapiens 19-22 23683960-14 2013 The use of DCM and THF as initial solvents provides the MEH-PPV nanoparticles with green (lambda max=535 nm) and red (lambda max=590 nm) photoemission, respectively. Methylene Chloride 11-14 epoxide hydrolase 1 Homo sapiens 56-59 23683960-14 2013 The use of DCM and THF as initial solvents provides the MEH-PPV nanoparticles with green (lambda max=535 nm) and red (lambda max=590 nm) photoemission, respectively. tetrahydrofuran 19-22 epoxide hydrolase 1 Homo sapiens 56-59 22415791-1 2013 Microsomal epoxide hydrolase (EPHX1) plays an important role in the activation and detoxification of polycyclic aromatic hydrocarbons, carcinogens found in cigarette smoke. Polycyclic Aromatic Hydrocarbons 101-133 epoxide hydrolase 1 Homo sapiens 0-28 22415791-1 2013 Microsomal epoxide hydrolase (EPHX1) plays an important role in the activation and detoxification of polycyclic aromatic hydrocarbons, carcinogens found in cigarette smoke. Polycyclic Aromatic Hydrocarbons 101-133 epoxide hydrolase 1 Homo sapiens 30-35 23742107-8 2013 We found a protective role of G6PD in AFB1-induced cytotoxicity, possibly via providing NADPH for NADPH oxidase to induce epoxide hydrolase 1 (EPHX1), a xenobiotic-metabolizing enzyme. NADP 88-93 epoxide hydrolase 1 Homo sapiens 122-141 23681797-1 2013 Microsomal epoxide hydrolase 1 (EPHX1) plays an important role in the detoxification of carcinogenic polycyclic aromatic hydrocarbons. Polycyclic Aromatic Hydrocarbons 101-133 epoxide hydrolase 1 Homo sapiens 32-37 23681797-10 2013 However, subgroup analysis by ethnicity further showed that there was an obvious association between EPHX1 His139Arg polymorphism and decreased risk of esophageal cancer in Caucasians (ArgArg versus HisArg/HisHis: OR = 0.52, 95 %CI 0.27-0.97, P = 0.041). arginylarginine 185-191 epoxide hydrolase 1 Homo sapiens 101-106 23681797-10 2013 However, subgroup analysis by ethnicity further showed that there was an obvious association between EPHX1 His139Arg polymorphism and decreased risk of esophageal cancer in Caucasians (ArgArg versus HisArg/HisHis: OR = 0.52, 95 %CI 0.27-0.97, P = 0.041). hisarg 199-205 epoxide hydrolase 1 Homo sapiens 101-106 23681797-10 2013 However, subgroup analysis by ethnicity further showed that there was an obvious association between EPHX1 His139Arg polymorphism and decreased risk of esophageal cancer in Caucasians (ArgArg versus HisArg/HisHis: OR = 0.52, 95 %CI 0.27-0.97, P = 0.041). histidylhistidine 206-212 epoxide hydrolase 1 Homo sapiens 101-106 23742107-8 2013 We found a protective role of G6PD in AFB1-induced cytotoxicity, possibly via providing NADPH for NADPH oxidase to induce epoxide hydrolase 1 (EPHX1), a xenobiotic-metabolizing enzyme. NADP 88-93 epoxide hydrolase 1 Homo sapiens 143-148 23797950-0 2013 Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers. Benzene 132-139 epoxide hydrolase 1 Homo sapiens 0-28 23797950-0 2013 Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers. Benzene 132-139 epoxide hydrolase 1 Homo sapiens 30-35 23797950-5 2013 We also observed that an increased number of C allele for rs1051740 in EPHX1 was associated with decreased ERCC3 methylation levels in benzene-exposed workers (P(trend) = 0.001), but not in unexposed controls (P(trend) = 0.379). Benzene 135-142 epoxide hydrolase 1 Homo sapiens 71-76 23797950-6 2013 Interestingly, another EPHX1 SNP (rs2234922) was associated with lower white blood cell (WBC) counts (P(trend) = 0.044) in benzene-exposed workers. Benzene 124-131 epoxide hydrolase 1 Homo sapiens 23-28 23797950-8 2013 Our findings suggest that benzene exposure may be associated with hypermethylation in ERCC3, and that genetic variants in EPHX1 may play an important role in epigenetic changes and hematotoxicity among benzene-exposed workers. Benzene 202-209 epoxide hydrolase 1 Homo sapiens 122-127 23858852-3 2013 The electroluminescent (EL) properties of the resulting polymers as an active layer, were investigated by the fabrication of single-layer LEDs and the devices using OXH-PPV-co-MEH-PPV showed better EL properties than those using pure MEH-PPV. Polymers 56-64 epoxide hydrolase 1 Homo sapiens 176-179 24053912-0 2013 [Influence of genetic polymorphisms of epoxide hydrolase 1 on metabolism of styrene in body]. Styrene 76-83 epoxide hydrolase 1 Homo sapiens 39-58 24053912-1 2013 OBJECTIVE: To investigate the role of genetic polymorphisms of epoxide hydrolase 1 (EPHX1) in the metabolism of styrene in vivo. Styrene 112-119 epoxide hydrolase 1 Homo sapiens 63-82 24053912-1 2013 OBJECTIVE: To investigate the role of genetic polymorphisms of epoxide hydrolase 1 (EPHX1) in the metabolism of styrene in vivo. Styrene 112-119 epoxide hydrolase 1 Homo sapiens 84-89 24053912-8 2013 CONCLUSION: Genetic polymorphisms of EPHX1 play an important role in the metabolic process of styrene in vivo. Styrene 94-101 epoxide hydrolase 1 Homo sapiens 37-42 23561572-7 2013 Exposure to C(2)-AP caused an up-regulation of DAX1 and EPHX, while exposure to NAs caused an up-regulation of ACTHR. c(2)-ap 12-19 epoxide hydrolase 1 Homo sapiens 56-60 23564882-1 2013 Microsomal epoxide hydrolase (mEH, EPHX1) is a critical xenobiotic-metabolizing enzyme, catalyzing both detoxification and bioactivation reactions that direct the disposition of chemical epoxides, including the carcinogenic metabolites of several polycyclic aromatic hydrocarbons. Epoxy Compounds 187-195 epoxide hydrolase 1 Homo sapiens 0-28 23564882-1 2013 Microsomal epoxide hydrolase (mEH, EPHX1) is a critical xenobiotic-metabolizing enzyme, catalyzing both detoxification and bioactivation reactions that direct the disposition of chemical epoxides, including the carcinogenic metabolites of several polycyclic aromatic hydrocarbons. Epoxy Compounds 187-195 epoxide hydrolase 1 Homo sapiens 35-40 23564882-1 2013 Microsomal epoxide hydrolase (mEH, EPHX1) is a critical xenobiotic-metabolizing enzyme, catalyzing both detoxification and bioactivation reactions that direct the disposition of chemical epoxides, including the carcinogenic metabolites of several polycyclic aromatic hydrocarbons. Polycyclic Aromatic Hydrocarbons 247-279 epoxide hydrolase 1 Homo sapiens 0-28 23564882-1 2013 Microsomal epoxide hydrolase (mEH, EPHX1) is a critical xenobiotic-metabolizing enzyme, catalyzing both detoxification and bioactivation reactions that direct the disposition of chemical epoxides, including the carcinogenic metabolites of several polycyclic aromatic hydrocarbons. Polycyclic Aromatic Hydrocarbons 247-279 epoxide hydrolase 1 Homo sapiens 35-40 23631598-0 2013 Experimental determination of the charge neutrality level of poly[2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene] (MEH-PPV). poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 61-117 epoxide hydrolase 1 Homo sapiens 120-123 23631598-1 2013 The charge neutrality level (CNL) of poly[2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene] (MEH-PPV) was determined. poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 37-93 epoxide hydrolase 1 Homo sapiens 96-99 23858852-3 2013 The electroluminescent (EL) properties of the resulting polymers as an active layer, were investigated by the fabrication of single-layer LEDs and the devices using OXH-PPV-co-MEH-PPV showed better EL properties than those using pure MEH-PPV. Polymers 56-64 epoxide hydrolase 1 Homo sapiens 234-237 23858852-3 2013 The electroluminescent (EL) properties of the resulting polymers as an active layer, were investigated by the fabrication of single-layer LEDs and the devices using OXH-PPV-co-MEH-PPV showed better EL properties than those using pure MEH-PPV. el 24-26 epoxide hydrolase 1 Homo sapiens 176-179 23646594-2 2013 The absorption spectra of nanocomposites of PbS CQDs and organic polymers, Poly[2-methoxy-5-(2"-ethylhexyloxy-pphenylenevinylene)] (MEH-PPV) and [6,6]-phenyl-C61-butyric acid methylester (PCBM), are the superposition of those of pristine constituents, indicating the absorption of the PbS CQDs contributes to the effective near-infrared light absorption for the photodiodes. Lead 44-47 epoxide hydrolase 1 Homo sapiens 132-135 26282143-2 2013 We show that an archetypical conjugated polymer, MEH-PPV, enhances its local structural and electronic order upon addition of an electronic acceptor, trinitrofluorenone (TNF). Polymers 40-47 epoxide hydrolase 1 Homo sapiens 49-52 26282143-2 2013 We show that an archetypical conjugated polymer, MEH-PPV, enhances its local structural and electronic order upon addition of an electronic acceptor, trinitrofluorenone (TNF). Trinitrofluorenone 150-168 epoxide hydrolase 1 Homo sapiens 49-52 26282143-3 2013 First, acceptor addition in MEH-PPV results in a highly structured XRD pattern characteristic for semicrystalline conjugated polymers. Polymers 125-133 epoxide hydrolase 1 Homo sapiens 28-31 26105914-8 2013 Furthermore we could show a fourfold reduction to encounter severe course of preeclampsia (defined as occurrence of HELLP-syndrome or eclampsia) in carriers of the EPHX1 polymorphism encoding histidine. Histidine 192-201 epoxide hydrolase 1 Homo sapiens 164-169 23061746-3 2013 The main objective of this study was to determine whether and to what extent variability in warfarin dose requirements was determined by polymorphisms in CYP2C9, VKORC1, CYP4F2 (rs2108622) and EPHX1 (rs2292566) in the Turkish population. Warfarin 92-100 epoxide hydrolase 1 Homo sapiens 193-198 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. PCBM 58-62 epoxide hydrolase 1 Homo sapiens 50-53 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. PCBM 58-62 epoxide hydrolase 1 Homo sapiens 135-138 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. PCBM 58-62 epoxide hydrolase 1 Homo sapiens 135-138 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. Lead 63-66 epoxide hydrolase 1 Homo sapiens 50-53 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. Lead 63-66 epoxide hydrolase 1 Homo sapiens 135-138 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. Lead 63-66 epoxide hydrolase 1 Homo sapiens 135-138 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. Lead 131-134 epoxide hydrolase 1 Homo sapiens 50-53 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. Lead 131-134 epoxide hydrolase 1 Homo sapiens 135-138 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. Lead 131-134 epoxide hydrolase 1 Homo sapiens 135-138 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. Lead 131-134 epoxide hydrolase 1 Homo sapiens 50-53 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. Lead 131-134 epoxide hydrolase 1 Homo sapiens 135-138 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. Lead 131-134 epoxide hydrolase 1 Homo sapiens 135-138 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. PCBM 151-155 epoxide hydrolase 1 Homo sapiens 50-53 23646594-3 2013 The enhanced photocurrent for photodiodes made of MEH-PPV:PCBM:PbS is attributed to the excitons dissociation at the interfaces of PbS/MEH-PPV and PbS/PCBM, as well as charge transport in MEH-PPV and PCBM. PCBM 151-155 epoxide hydrolase 1 Homo sapiens 50-53 23055191-1 2013 Microsomal epoxide hydrolase 1 (EPHX1) plays an important role in both the activation and the detoxification of polycyclic aromatic hydrocarbons and aromatic amines. Polycyclic Aromatic Hydrocarbons 112-144 epoxide hydrolase 1 Homo sapiens 32-37 23055191-1 2013 Microsomal epoxide hydrolase 1 (EPHX1) plays an important role in both the activation and the detoxification of polycyclic aromatic hydrocarbons and aromatic amines. aromatic amines 149-164 epoxide hydrolase 1 Homo sapiens 32-37 24455257-1 2013 MEH IS A CRITICAL BIOTRANSFORMATION ENZYME THAT CATALYZES THE CONVERSION OF XENOBIOTIC EPOXIDE SUBSTRATES INTO MORE POLAR DIOL METABOLITES: it is also capable of inactivating a large number of structurally different molecules. xenobiotic epoxide 76-94 epoxide hydrolase 1 Homo sapiens 0-3 24266295-2 2013 The first phase of xenobiotic biotransformation in the PAH metabolism includes activities of cytochrome P450 from the CYP1 family and microsomal epoxide hydrolase. Polycyclic Aromatic Hydrocarbons 55-58 epoxide hydrolase 1 Homo sapiens 134-162 22959619-4 2013 It has shown that MEH-PPV/Alq3 solutions are specifically sensitive to X-rays, since the effect of radiation on this organic system is strongly correlated with the efficient spectral overlap between Alq3 emission and the absorption of degraded MEH-PPV, which alters the color and photoemission of MEH-PPV/Alq3 mixtures from red to yellow, and then to green. tris-(8-hydroxyquinoline)aluminum 26-30 epoxide hydrolase 1 Homo sapiens 18-21 22959619-4 2013 It has shown that MEH-PPV/Alq3 solutions are specifically sensitive to X-rays, since the effect of radiation on this organic system is strongly correlated with the efficient spectral overlap between Alq3 emission and the absorption of degraded MEH-PPV, which alters the color and photoemission of MEH-PPV/Alq3 mixtures from red to yellow, and then to green. tris-(8-hydroxyquinoline)aluminum 26-30 epoxide hydrolase 1 Homo sapiens 244-247 22959619-4 2013 It has shown that MEH-PPV/Alq3 solutions are specifically sensitive to X-rays, since the effect of radiation on this organic system is strongly correlated with the efficient spectral overlap between Alq3 emission and the absorption of degraded MEH-PPV, which alters the color and photoemission of MEH-PPV/Alq3 mixtures from red to yellow, and then to green. tris-(8-hydroxyquinoline)aluminum 26-30 epoxide hydrolase 1 Homo sapiens 244-247 22959619-4 2013 It has shown that MEH-PPV/Alq3 solutions are specifically sensitive to X-rays, since the effect of radiation on this organic system is strongly correlated with the efficient spectral overlap between Alq3 emission and the absorption of degraded MEH-PPV, which alters the color and photoemission of MEH-PPV/Alq3 mixtures from red to yellow, and then to green. tris-(8-hydroxyquinoline)aluminum 199-203 epoxide hydrolase 1 Homo sapiens 18-21 22959619-4 2013 It has shown that MEH-PPV/Alq3 solutions are specifically sensitive to X-rays, since the effect of radiation on this organic system is strongly correlated with the efficient spectral overlap between Alq3 emission and the absorption of degraded MEH-PPV, which alters the color and photoemission of MEH-PPV/Alq3 mixtures from red to yellow, and then to green. tris-(8-hydroxyquinoline)aluminum 199-203 epoxide hydrolase 1 Homo sapiens 18-21 22959619-5 2013 The rate of this change is more sensitive when MEH-PPV/Alq3 is irradiated in the presence of benzoyl peroxide than when in the presence of hindered phenolic stabilizers, respectively, an accelerator and an inhibitor to activate or inhibit free radical formation. Benzoyl Peroxide 93-109 epoxide hydrolase 1 Homo sapiens 47-50 24455257-1 2013 MEH IS A CRITICAL BIOTRANSFORMATION ENZYME THAT CATALYZES THE CONVERSION OF XENOBIOTIC EPOXIDE SUBSTRATES INTO MORE POLAR DIOL METABOLITES: it is also capable of inactivating a large number of structurally different molecules. diol 122-126 epoxide hydrolase 1 Homo sapiens 0-3 24362093-1 2013 OBJECTIVES: Cytochrome P450 (CYP) 1A1 is the most important enzyme in both activation and detoxification of carcinogenic benzo[a]pyrene (BaP), in combination with microsomal epoxide hydrolase (mEH). Benzo(a)pyrene 121-135 epoxide hydrolase 1 Homo sapiens 163-191 23252947-4 2013 Significant association of EPHX1 SNPs was observed with greater carbamazepine-10,11-trans dihydrodiol:carbamazepine 10-11 epoxide ratios. carbamazepine-10,11-dihydrodiol 64-101 epoxide hydrolase 1 Homo sapiens 27-32 23252947-4 2013 Significant association of EPHX1 SNPs was observed with greater carbamazepine-10,11-trans dihydrodiol:carbamazepine 10-11 epoxide ratios. Carbamazepine 64-77 epoxide hydrolase 1 Homo sapiens 27-32 23252947-2 2013 MATERIALS & METHODS: Twenty-five SNPs within seven CBZ pathway genes, namely CYP3A4, CYP3A5, EPHX1, NR1I2, UGT2B7, ABCB1 and ABCC2, were analyzed for association with CBZ pharmacokinetics in 90 epilepsy patients. Carbamazepine 55-58 epoxide hydrolase 1 Homo sapiens 97-102 22775295-9 2012 This Account summarizes the effects of monomer regioregularity and backbone rigidity, by comparing a regiorandom phenylene vinylene (MEH-PPV) with both a regiorandom and regioregular thiophene (P3HT). phenylene vinylene 113-131 epoxide hydrolase 1 Homo sapiens 133-136 22161138-13 2012 Although with modest limitations and biases, this metaanalysis suggests that EPHX1 Tyr113His and His139Arg, GSTT1, GSTM1, GSTP1 Ile105Val and Ala114Val polymorphisms may be not risk factors for CRA development, while Ser allele of NQO1 Ser187 Pro may be a modest risk factor for CRA development, and may be used with other genetic markers for screening CRA in the future. tyr113his 83-92 epoxide hydrolase 1 Homo sapiens 77-82 23285845-0 2012 [All wavelength picosecond fluorescent anisotropy of aligned MEH-PPV/PVP electrospun fibers]. Povidone 69-72 epoxide hydrolase 1 Homo sapiens 61-64 23030277-0 2012 Controlling morphology and chain aggregation in semiconducting conjugated polymers: the role of solvent on optical gain in MEH-PPV. Polymers 74-82 epoxide hydrolase 1 Homo sapiens 123-126 23030277-1 2012 We report the results of a detailed investigation that addresses the influence of polymer morphology and chain aggregation, as controlled by the chemical nature of the solvent, on the optical gain properties of the conjugated polymer poly[2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene] (MEH-PPV). Polymers 226-233 epoxide hydrolase 1 Homo sapiens 293-296 23030277-1 2012 We report the results of a detailed investigation that addresses the influence of polymer morphology and chain aggregation, as controlled by the chemical nature of the solvent, on the optical gain properties of the conjugated polymer poly[2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene] (MEH-PPV). poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 234-291 epoxide hydrolase 1 Homo sapiens 293-296 22709266-1 2012 The poly(p-phenylene vinylene) derivative MEH-PPV is known to exist as two morphologically distinct species, referred to as red phase and blue phase. poly(4-phenylenevinylene) 4-30 epoxide hydrolase 1 Homo sapiens 42-45 22352736-2 2012 Microsomal epoxide hydrolase (EPHX1) has an important role in the metabolism of polycyclic aromatic hydrocarbons and detoxification of procarcinogens. Polycyclic Aromatic Hydrocarbons 80-112 epoxide hydrolase 1 Homo sapiens 0-28 22352736-2 2012 Microsomal epoxide hydrolase (EPHX1) has an important role in the metabolism of polycyclic aromatic hydrocarbons and detoxification of procarcinogens. Polycyclic Aromatic Hydrocarbons 80-112 epoxide hydrolase 1 Homo sapiens 30-35 22161138-13 2012 Although with modest limitations and biases, this metaanalysis suggests that EPHX1 Tyr113His and His139Arg, GSTT1, GSTM1, GSTP1 Ile105Val and Ala114Val polymorphisms may be not risk factors for CRA development, while Ser allele of NQO1 Ser187 Pro may be a modest risk factor for CRA development, and may be used with other genetic markers for screening CRA in the future. Serine 217-220 epoxide hydrolase 1 Homo sapiens 77-82 21983886-9 2012 In conclusion, individuals with EPHX1 113His/His slow activity genotype may not detoxify reactive carcinogenic epoxides efficiently, binding of reactive epoxides to DNA cause DNA damage. 113his 38-44 epoxide hydrolase 1 Homo sapiens 32-37 21983886-1 2012 Microsomal epoxide hydrolase, EPHX1, plays a central role in the detoxification of potentially genotoxic epoxide intermediates. Epoxy Compounds 11-18 epoxide hydrolase 1 Homo sapiens 30-35 21983886-9 2012 In conclusion, individuals with EPHX1 113His/His slow activity genotype may not detoxify reactive carcinogenic epoxides efficiently, binding of reactive epoxides to DNA cause DNA damage. Histidine 41-44 epoxide hydrolase 1 Homo sapiens 32-37 21983886-9 2012 In conclusion, individuals with EPHX1 113His/His slow activity genotype may not detoxify reactive carcinogenic epoxides efficiently, binding of reactive epoxides to DNA cause DNA damage. Epoxy Compounds 153-161 epoxide hydrolase 1 Homo sapiens 32-37 22196349-0 2012 Surface modification of poly(2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene) (MEH-PPV) by confined photo-catalytic oxidation. poly(2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene) 24-84 epoxide hydrolase 1 Homo sapiens 86-89 21883387-0 2012 Impact of genetic factors (VKORC1, CYP2C9, CYP4F2 and EPHX1) on the anticoagulation response to fluindione. fluindione 96-106 epoxide hydrolase 1 Homo sapiens 54-59 22755128-0 2012 Synthesis of capped TiO2 nanocrystals of controlled shape and their use with MEH-PPV to develop nanocomposite films for photovoltaic applications. titanium dioxide 20-24 epoxide hydrolase 1 Homo sapiens 77-80 22755128-3 2012 In order to develop nanocomposite thin films for photovoltaic cells, these TiO2 NPs were carefully dispersed in 2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene (MEH-PPV) matrix. titanium dioxide 75-79 epoxide hydrolase 1 Homo sapiens 165-168 22196349-1 2012 In this study, the surface of pi-conjugated polymer, poly(2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene) (MEH-PPV), was successfully modified with the sulfate anion (SO(4-)) groups by the confined photo-catalytic oxidation (CPO). Polymers 44-51 epoxide hydrolase 1 Homo sapiens 115-118 22196349-1 2012 In this study, the surface of pi-conjugated polymer, poly(2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene) (MEH-PPV), was successfully modified with the sulfate anion (SO(4-)) groups by the confined photo-catalytic oxidation (CPO). poly(2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene) 53-113 epoxide hydrolase 1 Homo sapiens 115-118 22196349-2 2012 After the surface modification, the water contact angle of MEH-PPV is changed from 95.5 to 82.1 without influence on its optical properties (based on the UV and PL spectra), and the water droplet can be absorbed on the modified MEH-PPV surface without sliding even at substrate tilt angles of 90 and 180 . Water 36-41 epoxide hydrolase 1 Homo sapiens 59-62 22196349-2 2012 After the surface modification, the water contact angle of MEH-PPV is changed from 95.5 to 82.1 without influence on its optical properties (based on the UV and PL spectra), and the water droplet can be absorbed on the modified MEH-PPV surface without sliding even at substrate tilt angles of 90 and 180 . Water 36-41 epoxide hydrolase 1 Homo sapiens 230-233 22196349-2 2012 After the surface modification, the water contact angle of MEH-PPV is changed from 95.5 to 82.1 without influence on its optical properties (based on the UV and PL spectra), and the water droplet can be absorbed on the modified MEH-PPV surface without sliding even at substrate tilt angles of 90 and 180 . Water 184-189 epoxide hydrolase 1 Homo sapiens 59-62 22196349-2 2012 After the surface modification, the water contact angle of MEH-PPV is changed from 95.5 to 82.1 without influence on its optical properties (based on the UV and PL spectra), and the water droplet can be absorbed on the modified MEH-PPV surface without sliding even at substrate tilt angles of 90 and 180 . Water 184-189 epoxide hydrolase 1 Homo sapiens 230-233 22196349-3 2012 The CPO on the MEH-PPV surface is able to further expand the use of MEH-PPV for applications. cpo 4-7 epoxide hydrolase 1 Homo sapiens 15-18 22196349-3 2012 The CPO on the MEH-PPV surface is able to further expand the use of MEH-PPV for applications. cpo 4-7 epoxide hydrolase 1 Homo sapiens 68-71 22196349-4 2012 In addition, the water transport test indicates that the modified MEH-PPV can be a candidate for transporting water droplet. Water 17-22 epoxide hydrolase 1 Homo sapiens 66-69 22196349-4 2012 In addition, the water transport test indicates that the modified MEH-PPV can be a candidate for transporting water droplet. Water 110-115 epoxide hydrolase 1 Homo sapiens 66-69 22200898-9 2012 The analyses also suggested an interaction between three genes involved in benzene metabolism CYP2E1, NQO1, and EPHX1. Benzene 75-82 epoxide hydrolase 1 Homo sapiens 112-117 22118311-1 2011 BACKGROUND/PURPOSE: Microsomal epoxide hydrolase (EPHX) is an important enzyme that metabolizes harmful reactive epoxides from smoking. reactive 104-112 epoxide hydrolase 1 Homo sapiens 20-48 22103900-2 2012 One of these enzymes is microsomal epoxide hydrolase (EPHX1) which metabolizes polycyclic aromatic hydrocarbons, or PAH, carcinogens found in cigarette smoke. Polycyclic Aromatic Hydrocarbons 79-111 epoxide hydrolase 1 Homo sapiens 24-52 22103900-2 2012 One of these enzymes is microsomal epoxide hydrolase (EPHX1) which metabolizes polycyclic aromatic hydrocarbons, or PAH, carcinogens found in cigarette smoke. Polycyclic Aromatic Hydrocarbons 79-111 epoxide hydrolase 1 Homo sapiens 54-59 22103900-2 2012 One of these enzymes is microsomal epoxide hydrolase (EPHX1) which metabolizes polycyclic aromatic hydrocarbons, or PAH, carcinogens found in cigarette smoke. Polycyclic Aromatic Hydrocarbons 116-119 epoxide hydrolase 1 Homo sapiens 24-52 22103900-2 2012 One of these enzymes is microsomal epoxide hydrolase (EPHX1) which metabolizes polycyclic aromatic hydrocarbons, or PAH, carcinogens found in cigarette smoke. Polycyclic Aromatic Hydrocarbons 116-119 epoxide hydrolase 1 Homo sapiens 54-59 22188362-0 2012 Association of polymorphisms in EPHX1, UGT2B7, ABCB1, ABCC2, SCN1A and SCN2A genes with carbamazepine therapy optimization. Carbamazepine 88-101 epoxide hydrolase 1 Homo sapiens 32-37 22188362-4 2012 Results of statistical analysis demonstrated that carriers of the variant SCN1A IVS5-91G>A and EPHX1 c.337T>C allele tended to require higher CBZ dosages and lower ln(concentration-dose ratios) than noncarriers (p < 0.0001) and the homozygous carriers also seemed to require higher CBZ dosages and lower ln(concentration-dose ratios) (p < 0.0001). Carbamazepine 148-151 epoxide hydrolase 1 Homo sapiens 98-103 22188362-4 2012 Results of statistical analysis demonstrated that carriers of the variant SCN1A IVS5-91G>A and EPHX1 c.337T>C allele tended to require higher CBZ dosages and lower ln(concentration-dose ratios) than noncarriers (p < 0.0001) and the homozygous carriers also seemed to require higher CBZ dosages and lower ln(concentration-dose ratios) (p < 0.0001). Carbamazepine 291-294 epoxide hydrolase 1 Homo sapiens 98-103 22188362-5 2012 In addition, the multiple regression model of concentration-dose ratio of CBZ also revealed that genetic variants in SCN1A, EPHX1 and UGT2B7 genes interactively affect the concentration-dose ratio of CBZ (adjusted r(2) = 55%). Carbamazepine 74-77 epoxide hydrolase 1 Homo sapiens 124-129 22188362-5 2012 In addition, the multiple regression model of concentration-dose ratio of CBZ also revealed that genetic variants in SCN1A, EPHX1 and UGT2B7 genes interactively affect the concentration-dose ratio of CBZ (adjusted r(2) = 55%). Carbamazepine 200-203 epoxide hydrolase 1 Homo sapiens 124-129 22047043-1 2011 The aggregation properties of a standard conjugated polymer, poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene) (MEH-PPV), in two distinct solvents (chloroform and toluene) and a range of polymer concentrations (c = 0.1-3 mg/mL) have been unequivocally resolved using combined dynamic and static light scatterings (DLS/SLS). Polymers 52-59 epoxide hydrolase 1 Homo sapiens 121-124 22118311-1 2011 BACKGROUND/PURPOSE: Microsomal epoxide hydrolase (EPHX) is an important enzyme that metabolizes harmful reactive epoxides from smoking. reactive 104-112 epoxide hydrolase 1 Homo sapiens 50-54 22118311-1 2011 BACKGROUND/PURPOSE: Microsomal epoxide hydrolase (EPHX) is an important enzyme that metabolizes harmful reactive epoxides from smoking. Epoxy Compounds 113-121 epoxide hydrolase 1 Homo sapiens 20-48 22118311-1 2011 BACKGROUND/PURPOSE: Microsomal epoxide hydrolase (EPHX) is an important enzyme that metabolizes harmful reactive epoxides from smoking. Epoxy Compounds 113-121 epoxide hydrolase 1 Homo sapiens 50-54 22118311-8 2011 RESULTS: Subjects with EPHX1 113 (His(113)/His(113)) homozygote mutation had a strong correlation with COPD (odds ratio: 2.7, 95% confidence interval: 1.5-5.2). Histidine 34-37 epoxide hydrolase 1 Homo sapiens 23-28 22118311-8 2011 RESULTS: Subjects with EPHX1 113 (His(113)/His(113)) homozygote mutation had a strong correlation with COPD (odds ratio: 2.7, 95% confidence interval: 1.5-5.2). Histidine 43-46 epoxide hydrolase 1 Homo sapiens 23-28 22413223-0 2011 Electroluminescence of zinc selenium (ZnSe) nanocrystals co-doped with poly[2-methoxy-5-(2"-ethylhexyloxy-p-phenylenevinylene)] (MEH-PPV). zinc selenium (znse) 23-43 epoxide hydrolase 1 Homo sapiens 129-132 21586816-1 2011 The hole transport properties of poly(2-methoxy, 5-(2"-ethyl-hexoxy)-p-phenylene vinylene) (MEH-PPV) blended with acid oxidized multiwall carbon nanotubes (COOH-MWCNTs) were investigated in a diode configuration using the time-of-flight (TOF) photocurrent method. poly(2-methoxy, 5-(2"-ethyl-hexoxy)-p-phenylene vinylene) 33-90 epoxide hydrolase 1 Homo sapiens 92-95 22413223-0 2011 Electroluminescence of zinc selenium (ZnSe) nanocrystals co-doped with poly[2-methoxy-5-(2"-ethylhexyloxy-p-phenylenevinylene)] (MEH-PPV). poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 71-127 epoxide hydrolase 1 Homo sapiens 129-132 22413223-2 2011 The synthesized ZnSe nanocrystals were co-doped with poly[2-methoxy-5-(2"-ethylhexyloxy-p-phenylenevinylene)] (MEH-PPV) to fabricate an organic/ inorganic hybrid multilayer light-emitting device (LED). poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 53-109 epoxide hydrolase 1 Homo sapiens 111-114 21812493-1 2011 This paper describes the simultaneous measurement of excitation and emission anisotropy to visualize energy transfer in single chains of the prototypical conjugated polymer MEH-PPV, for samples with >70% of the single chains organized into extended, rod-like conformations. Polymers 165-172 epoxide hydrolase 1 Homo sapiens 173-176 21839197-1 2011 In this work, a novel all-solid-state polymeric membrane Pb(2+)-selective electrode was developed by using for the first time poly(2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene) (MEH-PPV) as solid contact. Lead 57-59 epoxide hydrolase 1 Homo sapiens 185-188 21839197-1 2011 In this work, a novel all-solid-state polymeric membrane Pb(2+)-selective electrode was developed by using for the first time poly(2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene) (MEH-PPV) as solid contact. poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 126-183 epoxide hydrolase 1 Homo sapiens 185-188 21612291-1 2011 The Horner method was used to synthesize random copolymers of poly(2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene) (MEH-PPV) that incorporated different backbone-directing monomers. copolymers 48-58 epoxide hydrolase 1 Homo sapiens 121-124 21612291-1 2011 The Horner method was used to synthesize random copolymers of poly(2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene) (MEH-PPV) that incorporated different backbone-directing monomers. poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 62-119 epoxide hydrolase 1 Homo sapiens 121-124 21586816-1 2011 The hole transport properties of poly(2-methoxy, 5-(2"-ethyl-hexoxy)-p-phenylene vinylene) (MEH-PPV) blended with acid oxidized multiwall carbon nanotubes (COOH-MWCNTs) were investigated in a diode configuration using the time-of-flight (TOF) photocurrent method. Carbon 138-144 epoxide hydrolase 1 Homo sapiens 92-95 21586816-2 2011 While the room temperature hole mobility in pure MEH-PPV films was non-dispersive with positive field dependent mobility, MEH-PPV:COOH-MWCNT blended devices exhibited dispersive transport and negative field dependent mobility. Carbonic Acid 130-134 epoxide hydrolase 1 Homo sapiens 122-125 21586816-2 2011 While the room temperature hole mobility in pure MEH-PPV films was non-dispersive with positive field dependent mobility, MEH-PPV:COOH-MWCNT blended devices exhibited dispersive transport and negative field dependent mobility. mwcnt 135-140 epoxide hydrolase 1 Homo sapiens 122-125 21586816-3 2011 This indicates that the hole mobility in this composite is influenced by positional disorder caused by the presence of COOH-MWCNTs in the MEH-PPV matrix. Carbonic Acid 119-123 epoxide hydrolase 1 Homo sapiens 138-141 23794963-6 2011 All solution processed ambipolar device is fabricated with simple spin coating steps using poly(2-methoxy-5-(2-ethyl-hexyloxy)-1,4-phenylenevinylene) (MEH-PPV) end capped with polyhedral oligomeric silsesquioxanes (POSS) as active layer. poly(2-methoxy-5-(2-ethyl-hexyloxy)-1,4-phenylenevinylene) 91-149 epoxide hydrolase 1 Homo sapiens 151-154 21639946-4 2011 METHODS: Direct sequencing method was used to identify SNPs in CYP2C9, VKORC1, CYP4F2, EPHX1, PROC and GGCX genes in warfarin-treated patients. Warfarin 117-125 epoxide hydrolase 1 Homo sapiens 87-92 21711905-0 2011 Analytical model for the photocurrent-voltage characteristics of bilayer MEH-PPV/TiO2 photovoltaic devices. titanium dioxide 81-85 epoxide hydrolase 1 Homo sapiens 73-76 21711905-4 2011 Bilayer polymer/TiO2 cells consisting of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) and TiO2, with different thicknesses of the polymer and TiO2 films, were prepared for experimental purposes. Polymers 8-15 epoxide hydrolase 1 Homo sapiens 100-103 21711905-5 2011 The experimental results for the prepared bilayer MEH-PPV/TiO2 cells under different conditions are satisfactorily fitted to the model. titanium dioxide 58-62 epoxide hydrolase 1 Homo sapiens 50-53 21183608-6 2011 RESULTS: Children with the EPHX1 Arg/His or Arg/Arg genotypes at codon 139 were significantly associated with increased risks of lifetime asthma (adjusted OR [aOR] = 1.3; 95% CI, 1.1-1.7; and aOR = 1.5; 95% CI, 1.1-2.1, respectively). Arginine 33-36 epoxide hydrolase 1 Homo sapiens 27-32 21183608-6 2011 RESULTS: Children with the EPHX1 Arg/His or Arg/Arg genotypes at codon 139 were significantly associated with increased risks of lifetime asthma (adjusted OR [aOR] = 1.3; 95% CI, 1.1-1.7; and aOR = 1.5; 95% CI, 1.1-2.1, respectively). Histidine 37-40 epoxide hydrolase 1 Homo sapiens 27-32 21183608-8 2011 The risk of EPHX1 139Arg allele and 113Tyr-139Arg diplotype were of greater magnitude in higher compared with lower NO2 communities. Nitrogen Dioxide 116-119 epoxide hydrolase 1 Homo sapiens 12-17 21183608-9 2011 The increase of the effect from the EPHX1 139Arg allele with higher NO2 exposure was most marked in the GSTP1 Val allele and GSTM1 present genotype. Nitrogen Dioxide 68-71 epoxide hydrolase 1 Homo sapiens 36-41 21097530-7 2011 In conclusion, polymorphisms of GSTT1, EPHX1, MTHFR, MTR and NAT2 differentially affect the frequency of CTAs, CSAs and CTGs, showing interaction with smoking and age. csas 111-115 epoxide hydrolase 1 Homo sapiens 39-44 21097530-7 2011 In conclusion, polymorphisms of GSTT1, EPHX1, MTHFR, MTR and NAT2 differentially affect the frequency of CTAs, CSAs and CTGs, showing interaction with smoking and age. ctgs 120-124 epoxide hydrolase 1 Homo sapiens 39-44 21228703-7 2011 An association was found between microsomal epoxide hydrolase and less than 40 years of age at diagnosis of Crohn"s disease and microsomal epoxide hydrolase and azathiporine use in patients with ulcerative colitis. azathiporine 161-173 epoxide hydrolase 1 Homo sapiens 33-61 21472962-1 2011 Single poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV) molecules dispersed in thin poly(methylmethacrylate) films have been investigated by fluorescence emission, excitation and time-resolved spectroscopy at 1.2 K. For the molecular weight studied (~200 kDa) a bimodal distribution of emission maxima is observed. poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] 7-67 epoxide hydrolase 1 Homo sapiens 69-72 21405189-6 2011 For the blends the acceptor emission is in fact a composition of exciplex and MEH PPV emissions, the later being due to Forster energy transfer from PFO. poly(9,9-di-n-octyl-2,7-fluorene) 149-152 epoxide hydrolase 1 Homo sapiens 78-81 21183986-3 2011 In this study, we show that the macromolecular dynamics in solutions of the archetypical conjugated polymer, MEH-PPV, is essentially changed upon addition of an acceptor 2,4,7-trinitrofluorenone (TNF) by using dynamic light scattering (DLS). Polymers 100-107 epoxide hydrolase 1 Homo sapiens 109-112 21183986-3 2011 In this study, we show that the macromolecular dynamics in solutions of the archetypical conjugated polymer, MEH-PPV, is essentially changed upon addition of an acceptor 2,4,7-trinitrofluorenone (TNF) by using dynamic light scattering (DLS). 2,4,7-trinitrofluorenone 170-194 epoxide hydrolase 1 Homo sapiens 109-112 23794963-6 2011 All solution processed ambipolar device is fabricated with simple spin coating steps using poly(2-methoxy-5-(2-ethyl-hexyloxy)-1,4-phenylenevinylene) (MEH-PPV) end capped with polyhedral oligomeric silsesquioxanes (POSS) as active layer. silsesquioxanes 198-213 epoxide hydrolase 1 Homo sapiens 151-154 21228414-7 2011 The weak, nonsignificant overall association between benzene and diffuse large B-cell lymphoma (OR = 1.29, 95% CI: 0.84, 1.98) was increased among women AA for rs2234922 in the microsomal epoxide hydrolase gene, EPHX1 (OR = 1.77, 95% CI: 1.06, 2.97; P(interaction) = 0.06). Benzene 53-60 epoxide hydrolase 1 Homo sapiens 177-205 21228414-7 2011 The weak, nonsignificant overall association between benzene and diffuse large B-cell lymphoma (OR = 1.29, 95% CI: 0.84, 1.98) was increased among women AA for rs2234922 in the microsomal epoxide hydrolase gene, EPHX1 (OR = 1.77, 95% CI: 1.06, 2.97; P(interaction) = 0.06). Benzene 53-60 epoxide hydrolase 1 Homo sapiens 212-217 21139189-1 2011 Multi-layer heterostructure negative differential resistance devices based on poly-[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylenevinylene] (MEH-PPV) conducting polymer and CdSe quantum dots is reported. poly-[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylenevinylene] 78-138 epoxide hydrolase 1 Homo sapiens 140-143 20951227-11 2011 Finally, a more comprehensive study is warranted in order to better elucidate the involvement of EPHX1 genotypes combination in benzene genotoxicity. Benzene 128-135 epoxide hydrolase 1 Homo sapiens 97-102 21113536-3 2011 The study was done on individual poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV) molecules with average molecular weights ranging from 215,000 to 1,440,000 and with narrow weight distributions. poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene 33-92 epoxide hydrolase 1 Homo sapiens 95-98 21261274-6 2011 Compared to multilayer devices without PEO, devices with ITO/PEDOT:PSS/MEH-PPV:PEO blend/Al architecture show a 100 fold increase of luminous efficiency (LE) reaching a maximum of 0.45 cd/A for the blend at a brightness of 400 cd/m(2). DOP protocol 75-78 epoxide hydrolase 1 Homo sapiens 71-74 21261274-7 2011 A similar increase is obtained for the polymer light-emitting diode (PLED) pixels deposited by the LIFT process, although the maximum luminous efficiency only reaches 0.05 cd/A for MEH-PPV:PEO blend, which we have attributed to the fact that LIFT transfer was carried out in an ambient atmosphere. Polymers 39-46 epoxide hydrolase 1 Homo sapiens 181-184 21139189-1 2011 Multi-layer heterostructure negative differential resistance devices based on poly-[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylenevinylene] (MEH-PPV) conducting polymer and CdSe quantum dots is reported. Polymers 160-167 epoxide hydrolase 1 Homo sapiens 140-143 21139189-1 2011 Multi-layer heterostructure negative differential resistance devices based on poly-[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylenevinylene] (MEH-PPV) conducting polymer and CdSe quantum dots is reported. cdse 172-176 epoxide hydrolase 1 Homo sapiens 140-143 21139189-2 2011 The conducting polymer MEH-PPV acts as a barrier while CdSe quantum dots form the well layer. cdse 55-59 epoxide hydrolase 1 Homo sapiens 23-26 20842355-0 2010 VKORC1-1639G>A, CYP2C9, EPHX1691A>G genotype, body weight, and age are important predictors for warfarin maintenance doses in patients with mechanical heart valve prostheses in southwest China. Warfarin 102-110 epoxide hydrolase 1 Homo sapiens 27-31 21734345-7 2011 Analysis of combinations showed a significant association of 113His/His EPHX1/null-GSTM1 (OR=4.07) and null-GSTM1/105Val/Val GSTP1 (OR =3.56) genotypes with increased risk of COPD (respectively P=0.0094 and P=0.0153). 113his 61-67 epoxide hydrolase 1 Homo sapiens 72-77 21734345-7 2011 Analysis of combinations showed a significant association of 113His/His EPHX1/null-GSTM1 (OR=4.07) and null-GSTM1/105Val/Val GSTP1 (OR =3.56) genotypes with increased risk of COPD (respectively P=0.0094 and P=0.0153). Histidine 64-67 epoxide hydrolase 1 Homo sapiens 72-77 21734345-9 2011 Combination of 113His/His EPHX1/null-GSTM1 genotypes showed a significant association with the decrease of Delta FEV1 in patients (P =0.028).In conclusion, our results suggest combined EPHX1, GSTP1, GSTM1 and GSTT1 genetic polymorphisms may play a significant role in the development of COPD, emphysema and decline of the lung function. 113his 15-21 epoxide hydrolase 1 Homo sapiens 185-190 21446494-1 2011 The gravure printed single layer structure and bi-layer structure of MEH-PPV/rubrene organic light emitting diodes (OLEDs) were investigated in this work. rubrene 77-84 epoxide hydrolase 1 Homo sapiens 69-72 21446494-7 2011 The efficiency of the bi-layer MEH-PPV/rubrene structure was improved by a factor of 1.6 approximately 3.2, and the brightness was improved by a factor of 1.9 approximately 2.0 compared to the blended single layer structure. rubrene 39-46 epoxide hydrolase 1 Homo sapiens 31-34 21192345-0 2011 Exon sequencing and association analysis of EPHX1 genetic variants with maintenance warfarin dose in a multiethnic Asian population. Warfarin 85-93 epoxide hydrolase 1 Homo sapiens 44-49 21192345-1 2011 BACKGROUND AND OBJECTIVES: Warfarin inhibits vitamin K epoxide reductase, of which microsomal epoxide hydrolase is a putative member. Warfarin 27-35 epoxide hydrolase 1 Homo sapiens 83-111 21192345-2 2011 Several studies have found signals of association with warfarin maintenance dose in the EPHX1 gene. Warfarin 55-63 epoxide hydrolase 1 Homo sapiens 88-93 21192345-3 2011 The aim of this study was to determine the effects of EPHX1 variants on warfarin maintenance dose in a multiethnic Asian population. Warfarin 72-80 epoxide hydrolase 1 Homo sapiens 54-59 21192345-4 2011 METHODS: We sequenced the exons of EPHX1 using PCR and direct sequencing in 279 patients consisting of three major ethnic groups receiving maintenance warfarin with a stable international normalized ratio. Warfarin 151-159 epoxide hydrolase 1 Homo sapiens 35-40 27713373-6 2010 EPHX1 polymorphisms may be associated with the pharmacokinetics of carbamazepine and the risk of phenytoin-induced congenital malformations. Carbamazepine 67-80 epoxide hydrolase 1 Homo sapiens 0-5 20694242-2 2010 Single chains of conjugated polymers e.g. MEH-PPV (poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene) have become interesting objects for single molecule spectroscopy (SMS) studies. Polymers 28-36 epoxide hydrolase 1 Homo sapiens 42-45 20694242-2 2010 Single chains of conjugated polymers e.g. MEH-PPV (poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene) have become interesting objects for single molecule spectroscopy (SMS) studies. poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene 51-108 epoxide hydrolase 1 Homo sapiens 42-45 20694242-5 2010 It turned out that a sample showing isolated bright spots in fluorescence images could be obtained in a very broad concentration range of MEH-PPV when toluene was used as a solvent and PMMA as a matrix. Toluene 151-158 epoxide hydrolase 1 Homo sapiens 138-141 20694242-5 2010 It turned out that a sample showing isolated bright spots in fluorescence images could be obtained in a very broad concentration range of MEH-PPV when toluene was used as a solvent and PMMA as a matrix. Polymethyl Methacrylate 185-189 epoxide hydrolase 1 Homo sapiens 138-141 20707332-2 2010 Electrofluorescence measurements on isolated chains in a glassy matrix at 77 K show that the quenching efficiency for poly[2-methoxy-5-(2-ethylhexyloxy)-p-phenylenevinylene] (MEH-PPV) is an order of magnitude larger than that for either a ladder-type polymer (MeLPPP) or polyfluorene (PFH). poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 118-173 epoxide hydrolase 1 Homo sapiens 175-178 20707332-2 2010 Electrofluorescence measurements on isolated chains in a glassy matrix at 77 K show that the quenching efficiency for poly[2-methoxy-5-(2-ethylhexyloxy)-p-phenylenevinylene] (MEH-PPV) is an order of magnitude larger than that for either a ladder-type polymer (MeLPPP) or polyfluorene (PFH). Polymers 251-258 epoxide hydrolase 1 Homo sapiens 175-178 20707332-2 2010 Electrofluorescence measurements on isolated chains in a glassy matrix at 77 K show that the quenching efficiency for poly[2-methoxy-5-(2-ethylhexyloxy)-p-phenylenevinylene] (MEH-PPV) is an order of magnitude larger than that for either a ladder-type polymer (MeLPPP) or polyfluorene (PFH). melppp 260-266 epoxide hydrolase 1 Homo sapiens 175-178 20707332-2 2010 Electrofluorescence measurements on isolated chains in a glassy matrix at 77 K show that the quenching efficiency for poly[2-methoxy-5-(2-ethylhexyloxy)-p-phenylenevinylene] (MEH-PPV) is an order of magnitude larger than that for either a ladder-type polymer (MeLPPP) or polyfluorene (PFH). fluorene 271-283 epoxide hydrolase 1 Homo sapiens 175-178 20707332-2 2010 Electrofluorescence measurements on isolated chains in a glassy matrix at 77 K show that the quenching efficiency for poly[2-methoxy-5-(2-ethylhexyloxy)-p-phenylenevinylene] (MEH-PPV) is an order of magnitude larger than that for either a ladder-type polymer (MeLPPP) or polyfluorene (PFH). N-n-Propyl-N-formylhydrazine 285-288 epoxide hydrolase 1 Homo sapiens 175-178 21033690-1 2010 This paper describes the co-self-assembly of a polystyrene-poly(4-vinylpyridine)-poly(ethylene oxide) triblock copolymer with CdSe nanocrystals (quantum dots, QDs) and with a styrene compatible phenylenevinylene conjugated polymer (MEH-PPV) in mixtures of chloroform and 2-propanol. polystyrene-poly(4-vinylpyridine)-poly(ethylene oxide) triblock copolymer 47-120 epoxide hydrolase 1 Homo sapiens 232-235 21033690-1 2010 This paper describes the co-self-assembly of a polystyrene-poly(4-vinylpyridine)-poly(ethylene oxide) triblock copolymer with CdSe nanocrystals (quantum dots, QDs) and with a styrene compatible phenylenevinylene conjugated polymer (MEH-PPV) in mixtures of chloroform and 2-propanol. Styrene 51-58 epoxide hydrolase 1 Homo sapiens 232-235 21033690-1 2010 This paper describes the co-self-assembly of a polystyrene-poly(4-vinylpyridine)-poly(ethylene oxide) triblock copolymer with CdSe nanocrystals (quantum dots, QDs) and with a styrene compatible phenylenevinylene conjugated polymer (MEH-PPV) in mixtures of chloroform and 2-propanol. Polymers 113-120 epoxide hydrolase 1 Homo sapiens 232-235 27713373-6 2010 EPHX1 polymorphisms may be associated with the pharmacokinetics of carbamazepine and the risk of phenytoin-induced congenital malformations. Phenytoin 97-106 epoxide hydrolase 1 Homo sapiens 0-5 20087921-1 2010 Single-molecule spectroscopy techniques are used to investigate time fluctuations of the fluorescence properties of two different types of conjugated polymer, a polythiophene derivative (PDOPT) and a phenylene vinylene derivative (MEH-PPV), at 100 and 293 K. Linear correlation coefficients between fluorescence intensity and polarization are used to characterize fluctuations. Polymers 150-157 epoxide hydrolase 1 Homo sapiens 231-234 20687680-1 2010 In this paper, we examine the second-harmonic generation (SHG) from spin-cast films of the conjugated polymer poly(2-methoxy-5-(2(")-ethylhexyloxy)para-phenylenevinylene) (MEH-PPV). polymer poly(2-methoxy-5-(2(")-ethylhexyloxy)para-phenylenevinylene) 102-170 epoxide hydrolase 1 Homo sapiens 172-175 20827963-1 2010 Bulk heterojunction polymer solar cells based on the blend of MEH-PPV (poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene]) and PCBM (1-(3-mehyloxycarbonyl)propyl-phenyl[6,6]C61) were fabricated. Polymers 20-27 epoxide hydrolase 1 Homo sapiens 62-65 20827963-1 2010 Bulk heterojunction polymer solar cells based on the blend of MEH-PPV (poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene]) and PCBM (1-(3-mehyloxycarbonyl)propyl-phenyl[6,6]C61) were fabricated. poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene 71-128 epoxide hydrolase 1 Homo sapiens 62-65 20358949-1 2010 In this work, a nanoscale thick organic light emitting MEH-PPV (poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene]layer) was realized by gravure printing technology and its roughness was controlled by the solvent printing process. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene 64-120 epoxide hydrolase 1 Homo sapiens 55-58 20358949-6 2010 To control the roughness of the MEH-PPV organic layer, solvent printing was proposed in this work with various solvent mixture of chloroform, chlorobenzene and 1,2-dichlorobenzene on the top of the gravure printed MEH-PPV layers and a significant reduction in roughness was achieved. Chloroform 130-140 epoxide hydrolase 1 Homo sapiens 32-35 20358949-6 2010 To control the roughness of the MEH-PPV organic layer, solvent printing was proposed in this work with various solvent mixture of chloroform, chlorobenzene and 1,2-dichlorobenzene on the top of the gravure printed MEH-PPV layers and a significant reduction in roughness was achieved. chlorobenzene 142-155 epoxide hydrolase 1 Homo sapiens 32-35 20358949-6 2010 To control the roughness of the MEH-PPV organic layer, solvent printing was proposed in this work with various solvent mixture of chloroform, chlorobenzene and 1,2-dichlorobenzene on the top of the gravure printed MEH-PPV layers and a significant reduction in roughness was achieved. 2-dichlorobenzene 160-179 epoxide hydrolase 1 Homo sapiens 32-35 20358949-6 2010 To control the roughness of the MEH-PPV organic layer, solvent printing was proposed in this work with various solvent mixture of chloroform, chlorobenzene and 1,2-dichlorobenzene on the top of the gravure printed MEH-PPV layers and a significant reduction in roughness was achieved. 2-dichlorobenzene 160-179 epoxide hydrolase 1 Homo sapiens 214-217 20383792-0 2010 Microsomal epoxide hydrolase expression in the endometrial uterine corpus is regulated by progesterone during the menstrual cycle. Progesterone 90-102 epoxide hydrolase 1 Homo sapiens 0-28 20383792-1 2010 We have shown previously that high expression levels of microsomal epoxide hydrolase (mEH) correlate with a poor prognosis of breast cancer patients receiving tamoxifen, suggesting that enhanced mEH expression could lead to antiestrogen resistance (Fritz et al. Tamoxifen 159-168 epoxide hydrolase 1 Homo sapiens 56-84 20548994-1 2010 Recent single molecule experiments have suggested the existence of a photochemical funnel in the photophysics of conjugated polymers, like poly[2-methoxy-5-(2"-ethylhexyl)oxy-1,4-phenylenevinylene] (MEH-PPV). Polymers 124-132 epoxide hydrolase 1 Homo sapiens 199-202 20548994-1 2010 Recent single molecule experiments have suggested the existence of a photochemical funnel in the photophysics of conjugated polymers, like poly[2-methoxy-5-(2"-ethylhexyl)oxy-1,4-phenylenevinylene] (MEH-PPV). poly[2-methoxy-5-(2"-ethylhexyl)oxy-1,4-phenylenevinylene] 139-197 epoxide hydrolase 1 Homo sapiens 199-202 21472306-2 2010 Two polymorphic sites have been described in exons 3 and 4 of the microsomal epoxide hydrolase gene that change tyrosine residue 113 to histidine (Tyr113His) and histidine 139 to arginine (His139Arg), respectively. his139arg 189-198 epoxide hydrolase 1 Homo sapiens 66-94 20396825-1 2010 The donor-acceptor ground-state charge-transfer complex (CTC) formed in solution between a conjugated polymer, poly[methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene-vinylene] (MEH-PPV), and a low-molecular-weight organic acceptor, 2,4,7-trinitrofluorenone (TNF), is studied by optical absorption and Raman spectroscopy. poly[methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene-vinylene] 111-168 epoxide hydrolase 1 Homo sapiens 170-173 20087921-1 2010 Single-molecule spectroscopy techniques are used to investigate time fluctuations of the fluorescence properties of two different types of conjugated polymer, a polythiophene derivative (PDOPT) and a phenylene vinylene derivative (MEH-PPV), at 100 and 293 K. Linear correlation coefficients between fluorescence intensity and polarization are used to characterize fluctuations. phenylene vinylene 200-218 epoxide hydrolase 1 Homo sapiens 231-234 20087921-3 2010 Furthermore, the polarization data reveal clear differences in the topology of these two polymers, which is related to the ordered conformation of the MEH-PPV. Polymers 89-97 epoxide hydrolase 1 Homo sapiens 151-154 19957937-1 2010 Chain-grafted Au nanoparticles were synthesized and incorporated into a fluorescent polymer, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV), host. Gold 14-16 epoxide hydrolase 1 Homo sapiens 152-155 19957937-1 2010 Chain-grafted Au nanoparticles were synthesized and incorporated into a fluorescent polymer, poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV), host. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene 93-149 epoxide hydrolase 1 Homo sapiens 152-155 19957937-2 2010 We show that control of the Au nanoparticle distribution within MEH-PPV is achieved by manipulating the enthalpic and entropic interactions between the grafted brush layers and the host chains. Gold 28-30 epoxide hydrolase 1 Homo sapiens 64-67 19957937-3 2010 Further, we show that the fluorescence of these Au/MEH-PPV nanocomposite thin films may be "tailored" by as much as an order of magnitude through changes in the nanoparticle distribution, brush length, and nanoparticle size. Gold 48-50 epoxide hydrolase 1 Homo sapiens 51-54 20210137-0 2009 [Investigation of luminescence mechanism of hybrid MEH-PPV/ SiO2 and super liner characteristic of amorphous SiO2]. Silicon Dioxide 60-64 epoxide hydrolase 1 Homo sapiens 51-54 20173887-3 2010 Both, steady-state fluorescence spectra and time-resolved fluorescence measurements indicate varying energy transfer efficiencies from the host polymer PF to the acceptor polymer MEH-PPV depending on the D-A distances and structural properties of the nanoparticles. polymer pf 144-154 epoxide hydrolase 1 Homo sapiens 179-182 19794411-0 2010 Genetic factors (VKORC1, CYP2C9, EPHX1, and CYP4F2) are predictor variables for warfarin response in very elderly, frail inpatients. Warfarin 80-88 epoxide hydrolase 1 Homo sapiens 33-38 19794411-4 2010 In addition to age, genetic variants of VKORC1, CYP2C9, CYP4F2, and EPHX1 were found to be significant predictor variables for the maintenance dose of warfarin, explaining 26.6% of dose variability. Warfarin 151-159 epoxide hydrolase 1 Homo sapiens 68-73 19952982-0 2010 Maternal EPHX1 polymorphisms and risk of phenytoin-induced congenital malformations. Phenytoin 41-50 epoxide hydrolase 1 Homo sapiens 9-14 19952982-2 2010 The goal of this study was to assess the effect of maternal genotype of functional polymorphisms in two genes involved in phenytoin metabolism, CYP2C9 (R144C, I395L) and EPHX1 (Y113H, H139R), on the presence of major craniofacial abnormalities (CFAs) in the child. Phenytoin 122-131 epoxide hydrolase 1 Homo sapiens 170-175 19952982-6 2010 In a logistic regression model adjusted for history of phenytoin use during the first trimester and maternal epilepsy (N=157 pregnancies), the maternal EPHX1 113 H [per rare allele odds ratio (OR): 2.43, 95% confidence interval (CI): 1.16-5.10, P=0.02] and 139 R (per rare allele OR: 2.33, 95% CI: 1.09-5.00, P=0.03) alleles were associated with CFAs in the child. Phenytoin 55-64 epoxide hydrolase 1 Homo sapiens 152-157 19952982-9 2010 CONCLUSION: Maternal EPHX1 genotype may be associated with risk of fetal anomalies among pregnant women taking phenytoin. Phenytoin 111-120 epoxide hydrolase 1 Homo sapiens 21-26 20210137-1 2009 For electricity induced luminescence of thin film, the heterojunction luminescence devices were produced by compounding the organic polymer of MEH-PPV and inorganic semiconductor SiO2. Polymers 132-139 epoxide hydrolase 1 Homo sapiens 143-146 20210137-3 2009 The obvious feature of electroluminescence in the luminescence device with ITO/SiO2/MEH-PPV/SiO2/Al is that it has two spectral bands. Silicon Dioxide 92-96 epoxide hydrolase 1 Homo sapiens 84-87 20210137-3 2009 The obvious feature of electroluminescence in the luminescence device with ITO/SiO2/MEH-PPV/SiO2/Al is that it has two spectral bands. Aluminum 97-99 epoxide hydrolase 1 Homo sapiens 84-87 19958090-7 2009 In addition, our results showed that CYP2C18, PROC and EPHX1 have small but significant associations with warfarin dose. Warfarin 106-114 epoxide hydrolase 1 Homo sapiens 55-60 19860455-1 2009 Single chains of the conjugated polymer MEH-PPV (poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene)) were studied with wide-field fluorescence microscopy (dispersion in inert polymer matrices) and with fluorescence correlation spectroscopy (chloroform solution). poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene) 49-107 epoxide hydrolase 1 Homo sapiens 40-43 19795866-1 2009 Absolute rate constants were determined for the abstraction of hydrogen atoms from (OC)(3)Fe(mu-SH)(2)Fe(CO)(3) (Fe(2)S(2)H(2)) and (OC)(3)Fe(mu-SCH(3))(mu-SH)Fe(CO)(3) (Fe(2)S(2)MeH) by benzyl radicals in benzene. Hydrogen 63-71 epoxide hydrolase 1 Homo sapiens 179-182 19863138-1 2009 Single-particle fluorescence spectroelectrochemistry was used to investigate the electrochemical oxidation of isolated, immobilized particles of the conjugated polymers BEH-PPV and MEH-PPV at an indium tin oxide (ITO) electrode immersed in an electrolyte solution. indium tin oxide 195-211 epoxide hydrolase 1 Homo sapiens 181-184 19997452-1 2009 Optical-quality, melt processable thick films of a conjugated polymer blend containing poly(2-methoxy-5-(2-ethyl-hexyloxy)-(phenylene vinylene)) (MEH-PPV), a C(60) derivative (PCBM) and a plasticizer (1,2-di-iso-octylphthalate) have been developed and their nonlinear absorption and optical limiting properties have been investigated. Polymers 62-69 epoxide hydrolase 1 Homo sapiens 146-149 19997452-3 2009 The dispersion of the optical limiting figure-of-merit of the MEH-PPV:PCBM:DOP blend shows a peak near the wavelength of the MEH-PPV cation, indicating an important role of one-photon and two-photon induced charge transfer in the nonlinear absorption response. PCBM 70-74 epoxide hydrolase 1 Homo sapiens 62-65 19997452-3 2009 The dispersion of the optical limiting figure-of-merit of the MEH-PPV:PCBM:DOP blend shows a peak near the wavelength of the MEH-PPV cation, indicating an important role of one-photon and two-photon induced charge transfer in the nonlinear absorption response. PCBM 70-74 epoxide hydrolase 1 Homo sapiens 125-128 19997452-3 2009 The dispersion of the optical limiting figure-of-merit of the MEH-PPV:PCBM:DOP blend shows a peak near the wavelength of the MEH-PPV cation, indicating an important role of one-photon and two-photon induced charge transfer in the nonlinear absorption response. Diethylhexyl Phthalate 75-78 epoxide hydrolase 1 Homo sapiens 62-65 19997452-3 2009 The dispersion of the optical limiting figure-of-merit of the MEH-PPV:PCBM:DOP blend shows a peak near the wavelength of the MEH-PPV cation, indicating an important role of one-photon and two-photon induced charge transfer in the nonlinear absorption response. Diethylhexyl Phthalate 75-78 epoxide hydrolase 1 Homo sapiens 125-128 19795866-1 2009 Absolute rate constants were determined for the abstraction of hydrogen atoms from (OC)(3)Fe(mu-SH)(2)Fe(CO)(3) (Fe(2)S(2)H(2)) and (OC)(3)Fe(mu-SCH(3))(mu-SH)Fe(CO)(3) (Fe(2)S(2)MeH) by benzyl radicals in benzene. siderite 102-111 epoxide hydrolase 1 Homo sapiens 179-182 19795866-1 2009 Absolute rate constants were determined for the abstraction of hydrogen atoms from (OC)(3)Fe(mu-SH)(2)Fe(CO)(3) (Fe(2)S(2)H(2)) and (OC)(3)Fe(mu-SCH(3))(mu-SH)Fe(CO)(3) (Fe(2)S(2)MeH) by benzyl radicals in benzene. Iron 90-92 epoxide hydrolase 1 Homo sapiens 179-182 19795866-1 2009 Absolute rate constants were determined for the abstraction of hydrogen atoms from (OC)(3)Fe(mu-SH)(2)Fe(CO)(3) (Fe(2)S(2)H(2)) and (OC)(3)Fe(mu-SCH(3))(mu-SH)Fe(CO)(3) (Fe(2)S(2)MeH) by benzyl radicals in benzene. Iron 102-104 epoxide hydrolase 1 Homo sapiens 179-182 19795866-2 2009 From the temperature-dependent rate data for Fe(2)S(2)H(2), DeltaH(++) and DeltaS(++) were determined to be 2.03 +/- 0.56 kcal/mol and -19.3 +/- 1.7 cal/(mol K), respectively, giving k(abs) = (1.2 +/- 0.49) x 10(7) M(-1) s(-1) at 25 degrees C. For Fe(2)S(2)MeH, DeltaH(++) and DeltaS(++) were determined to be 1.97 +/- 0.46 kcal/mol and -18.1 +/- 1.5 cal/(mol K), respectively, giving k(abs) = (2.3 +/- 0.23) x 10(7) M(-1) s(-1) at 25 degrees C. Temperature-dependent rate data are also reported for hydrogen atom abstraction by benzyl radical from thiophenol (DeltaH(++) = 3.62 +/- 0.43 kcal/mol, DeltaS(++) = -21.7 +/- 1.3 cal/(mol K)) and H(2)S (DeltaH(++) = 5.13 +/- 0.99 kcal/mol, DeltaS(++) = -24.8 +/- 3.2 cal/(mol K)), giving k(abs) at 25 degrees C of (2.5 +/- 0.33) x 10(5) and (4.2 +/- 0.51) x 10(3) M(-1) s(-1), respectively, both having hydrogen atom abstraction rate constants orders of magnitude slower than those of Fe(2)S(2)H(2) and Fe(2)S(2)MeH. deltah 60-66 epoxide hydrolase 1 Homo sapiens 257-260 19795866-2 2009 From the temperature-dependent rate data for Fe(2)S(2)H(2), DeltaH(++) and DeltaS(++) were determined to be 2.03 +/- 0.56 kcal/mol and -19.3 +/- 1.7 cal/(mol K), respectively, giving k(abs) = (1.2 +/- 0.49) x 10(7) M(-1) s(-1) at 25 degrees C. For Fe(2)S(2)MeH, DeltaH(++) and DeltaS(++) were determined to be 1.97 +/- 0.46 kcal/mol and -18.1 +/- 1.5 cal/(mol K), respectively, giving k(abs) = (2.3 +/- 0.23) x 10(7) M(-1) s(-1) at 25 degrees C. Temperature-dependent rate data are also reported for hydrogen atom abstraction by benzyl radical from thiophenol (DeltaH(++) = 3.62 +/- 0.43 kcal/mol, DeltaS(++) = -21.7 +/- 1.3 cal/(mol K)) and H(2)S (DeltaH(++) = 5.13 +/- 0.99 kcal/mol, DeltaS(++) = -24.8 +/- 3.2 cal/(mol K)), giving k(abs) at 25 degrees C of (2.5 +/- 0.33) x 10(5) and (4.2 +/- 0.51) x 10(3) M(-1) s(-1), respectively, both having hydrogen atom abstraction rate constants orders of magnitude slower than those of Fe(2)S(2)H(2) and Fe(2)S(2)MeH. deltah 60-66 epoxide hydrolase 1 Homo sapiens 958-961 19795866-2 2009 From the temperature-dependent rate data for Fe(2)S(2)H(2), DeltaH(++) and DeltaS(++) were determined to be 2.03 +/- 0.56 kcal/mol and -19.3 +/- 1.7 cal/(mol K), respectively, giving k(abs) = (1.2 +/- 0.49) x 10(7) M(-1) s(-1) at 25 degrees C. For Fe(2)S(2)MeH, DeltaH(++) and DeltaS(++) were determined to be 1.97 +/- 0.46 kcal/mol and -18.1 +/- 1.5 cal/(mol K), respectively, giving k(abs) = (2.3 +/- 0.23) x 10(7) M(-1) s(-1) at 25 degrees C. Temperature-dependent rate data are also reported for hydrogen atom abstraction by benzyl radical from thiophenol (DeltaH(++) = 3.62 +/- 0.43 kcal/mol, DeltaS(++) = -21.7 +/- 1.3 cal/(mol K)) and H(2)S (DeltaH(++) = 5.13 +/- 0.99 kcal/mol, DeltaS(++) = -24.8 +/- 3.2 cal/(mol K)), giving k(abs) at 25 degrees C of (2.5 +/- 0.33) x 10(5) and (4.2 +/- 0.51) x 10(3) M(-1) s(-1), respectively, both having hydrogen atom abstraction rate constants orders of magnitude slower than those of Fe(2)S(2)H(2) and Fe(2)S(2)MeH. ammonium ferrous sulfate 45-51 epoxide hydrolase 1 Homo sapiens 257-260 19795866-2 2009 From the temperature-dependent rate data for Fe(2)S(2)H(2), DeltaH(++) and DeltaS(++) were determined to be 2.03 +/- 0.56 kcal/mol and -19.3 +/- 1.7 cal/(mol K), respectively, giving k(abs) = (1.2 +/- 0.49) x 10(7) M(-1) s(-1) at 25 degrees C. For Fe(2)S(2)MeH, DeltaH(++) and DeltaS(++) were determined to be 1.97 +/- 0.46 kcal/mol and -18.1 +/- 1.5 cal/(mol K), respectively, giving k(abs) = (2.3 +/- 0.23) x 10(7) M(-1) s(-1) at 25 degrees C. Temperature-dependent rate data are also reported for hydrogen atom abstraction by benzyl radical from thiophenol (DeltaH(++) = 3.62 +/- 0.43 kcal/mol, DeltaS(++) = -21.7 +/- 1.3 cal/(mol K)) and H(2)S (DeltaH(++) = 5.13 +/- 0.99 kcal/mol, DeltaS(++) = -24.8 +/- 3.2 cal/(mol K)), giving k(abs) at 25 degrees C of (2.5 +/- 0.33) x 10(5) and (4.2 +/- 0.51) x 10(3) M(-1) s(-1), respectively, both having hydrogen atom abstraction rate constants orders of magnitude slower than those of Fe(2)S(2)H(2) and Fe(2)S(2)MeH. ammonium ferrous sulfate 45-51 epoxide hydrolase 1 Homo sapiens 958-961 19795866-5 2009 DFT calculations predict S-H bond strengths of 73.1 and 73.2 kcal/mol for Fe(2)S(2)H(2) and Fe(2)S(2)MeH, respectively. ammonium ferrous sulfate 92-98 epoxide hydrolase 1 Homo sapiens 101-104 19795866-8 2009 The S-H solution bond dissociation free energy (SBDFE) of Fe(2)S(2)MeH was found to be 69.4 +/- 1.7 kcal/mol by determination of its pK(a) (16.0 +/- 0.4) and the potential for the oxidation of the anion, Fe(2)S(2)Me(-), of -0.26 +/- 0.05 V vs ferrocene in acetonitrile (corrected for dimerization of Fe(2)S(2)Me(*)). ammonium ferrous sulfate 58-64 epoxide hydrolase 1 Homo sapiens 67-70 19795866-8 2009 The S-H solution bond dissociation free energy (SBDFE) of Fe(2)S(2)MeH was found to be 69.4 +/- 1.7 kcal/mol by determination of its pK(a) (16.0 +/- 0.4) and the potential for the oxidation of the anion, Fe(2)S(2)Me(-), of -0.26 +/- 0.05 V vs ferrocene in acetonitrile (corrected for dimerization of Fe(2)S(2)Me(*)). ferrocene 243-252 epoxide hydrolase 1 Homo sapiens 67-70 19795866-8 2009 The S-H solution bond dissociation free energy (SBDFE) of Fe(2)S(2)MeH was found to be 69.4 +/- 1.7 kcal/mol by determination of its pK(a) (16.0 +/- 0.4) and the potential for the oxidation of the anion, Fe(2)S(2)Me(-), of -0.26 +/- 0.05 V vs ferrocene in acetonitrile (corrected for dimerization of Fe(2)S(2)Me(*)). acetonitrile 256-268 epoxide hydrolase 1 Homo sapiens 67-70 19791819-0 2009 A new family of color-tunable light-emitting polymers with high quantum yields via the controlled oxidation of MEH-PPV. Polymers 45-53 epoxide hydrolase 1 Homo sapiens 111-114 19795866-8 2009 The S-H solution bond dissociation free energy (SBDFE) of Fe(2)S(2)MeH was found to be 69.4 +/- 1.7 kcal/mol by determination of its pK(a) (16.0 +/- 0.4) and the potential for the oxidation of the anion, Fe(2)S(2)Me(-), of -0.26 +/- 0.05 V vs ferrocene in acetonitrile (corrected for dimerization of Fe(2)S(2)Me(*)). ammonium ferrous sulfate 204-210 epoxide hydrolase 1 Homo sapiens 67-70 19791819-1 2009 We report a new method to generate families of organic fluorophores with any desirable emission wavelengths based upon the controlled oxidation of the light-emitting conjugated polymer, poly[2-methoxy-5-(2"-ethylhexyloxy)-p-phenylenevinylene] (MEH-PPV), with meta-chloroperbenzoic acid (m-CPBA). Polymers 177-184 epoxide hydrolase 1 Homo sapiens 244-247 19795866-9 2009 This SBDFE for Fe(2)S(2)MeH corresponds to a gas-phase bond dissociation enthalpy (BDE) of 74.2 kcal/mol, in satisfactory agreement with the DFT value of 73.2 kcal/mol. sbdfe 5-10 epoxide hydrolase 1 Homo sapiens 24-27 19791819-2 2009 In this method, m-CPBA reacts with ethylene moieties along the MEH-PPV backbone to create conjugation breaks, which gives rise to a gradual and controllable change in the emission wavelength. cpba 18-22 epoxide hydrolase 1 Homo sapiens 63-66 19791819-2 2009 In this method, m-CPBA reacts with ethylene moieties along the MEH-PPV backbone to create conjugation breaks, which gives rise to a gradual and controllable change in the emission wavelength. ethylene 35-43 epoxide hydrolase 1 Homo sapiens 63-66 19795866-10 2009 Replacement of the Fe-Fe bond in Fe(2)S(2)MeH with bridging mu-S (Fe(2)S(3)MeH) or mu-CO (Fe(2)S(2)(CO)MeH) groups leads to (DFT) BDEs of 72.8 and 66.2 kcal/mol, the latter indicating dramatic effects of the choice of bridge structure on S-H bond strengths. Iron 19-21 epoxide hydrolase 1 Homo sapiens 42-45 19795866-10 2009 Replacement of the Fe-Fe bond in Fe(2)S(2)MeH with bridging mu-S (Fe(2)S(3)MeH) or mu-CO (Fe(2)S(2)(CO)MeH) groups leads to (DFT) BDEs of 72.8 and 66.2 kcal/mol, the latter indicating dramatic effects of the choice of bridge structure on S-H bond strengths. Iron 22-24 epoxide hydrolase 1 Homo sapiens 42-45 19795866-10 2009 Replacement of the Fe-Fe bond in Fe(2)S(2)MeH with bridging mu-S (Fe(2)S(3)MeH) or mu-CO (Fe(2)S(2)(CO)MeH) groups leads to (DFT) BDEs of 72.8 and 66.2 kcal/mol, the latter indicating dramatic effects of the choice of bridge structure on S-H bond strengths. ammonium ferrous sulfate 33-39 epoxide hydrolase 1 Homo sapiens 42-45 19795866-10 2009 Replacement of the Fe-Fe bond in Fe(2)S(2)MeH with bridging mu-S (Fe(2)S(3)MeH) or mu-CO (Fe(2)S(2)(CO)MeH) groups leads to (DFT) BDEs of 72.8 and 66.2 kcal/mol, the latter indicating dramatic effects of the choice of bridge structure on S-H bond strengths. ammonium ferrous sulfate 33-39 epoxide hydrolase 1 Homo sapiens 75-78 19795866-10 2009 Replacement of the Fe-Fe bond in Fe(2)S(2)MeH with bridging mu-S (Fe(2)S(3)MeH) or mu-CO (Fe(2)S(2)(CO)MeH) groups leads to (DFT) BDEs of 72.8 and 66.2 kcal/mol, the latter indicating dramatic effects of the choice of bridge structure on S-H bond strengths. ammonium ferrous sulfate 33-39 epoxide hydrolase 1 Homo sapiens 75-78 19787692-0 2009 Effect of PCBM concentration on photoluminescence properties of composite MEH-PPV/PCBM nanoparticles investigated by a Franck-Condon analysis of single-particle emission spectra. PCBM 10-14 epoxide hydrolase 1 Homo sapiens 74-77 19795866-10 2009 Replacement of the Fe-Fe bond in Fe(2)S(2)MeH with bridging mu-S (Fe(2)S(3)MeH) or mu-CO (Fe(2)S(2)(CO)MeH) groups leads to (DFT) BDEs of 72.8 and 66.2 kcal/mol, the latter indicating dramatic effects of the choice of bridge structure on S-H bond strengths. ammonium ferrous sulfate 66-72 epoxide hydrolase 1 Homo sapiens 42-45 19787692-1 2009 The emission of composite conjugated polymer (MEH-PPV)/fullerene (PCBM) nanoparticles is investigated by single particle spectroscopy (SPS), and changes in vibronic structure with nanoparticle composition are evaluated by means of a detailed Franck-Condon analysis. Polymers 37-44 epoxide hydrolase 1 Homo sapiens 46-49 19795866-10 2009 Replacement of the Fe-Fe bond in Fe(2)S(2)MeH with bridging mu-S (Fe(2)S(3)MeH) or mu-CO (Fe(2)S(2)(CO)MeH) groups leads to (DFT) BDEs of 72.8 and 66.2 kcal/mol, the latter indicating dramatic effects of the choice of bridge structure on S-H bond strengths. ammonium ferrous sulfate 66-72 epoxide hydrolase 1 Homo sapiens 42-45 19127076-2 2009 To further understand the molecular mechanism of this adverse reaction, analyses of the genetic variants of human leukocyte antigen (HLA) and of the epoxide hydrolase gene (EPHX1), previously associated with carbamazepine hypersensitivity, were performed. Carbamazepine 208-221 epoxide hydrolase 1 Homo sapiens 173-178 19787692-1 2009 The emission of composite conjugated polymer (MEH-PPV)/fullerene (PCBM) nanoparticles is investigated by single particle spectroscopy (SPS), and changes in vibronic structure with nanoparticle composition are evaluated by means of a detailed Franck-Condon analysis. Sodium phenolsulfonate 135-138 epoxide hydrolase 1 Homo sapiens 46-49 19672545-1 2009 Polarization-sensitive time-resolved visible-infrared pump-probe experiments demonstrate that one can efficiently generate long-lived charges in donor-acceptor charge transfer complex (CTC) of conjugated polymer doped with fullerene, MEH-PPV/dinitroanthraquinone/C(60). Polymers 204-211 epoxide hydrolase 1 Homo sapiens 234-237 19672545-1 2009 Polarization-sensitive time-resolved visible-infrared pump-probe experiments demonstrate that one can efficiently generate long-lived charges in donor-acceptor charge transfer complex (CTC) of conjugated polymer doped with fullerene, MEH-PPV/dinitroanthraquinone/C(60). dinitroanthraquinone 242-262 epoxide hydrolase 1 Homo sapiens 234-237 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. Epoxy Compounds 11-18 epoxide hydrolase 1 Homo sapiens 30-35 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. Phenytoin 159-168 epoxide hydrolase 1 Homo sapiens 0-28 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. Phenytoin 159-168 epoxide hydrolase 1 Homo sapiens 30-35 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. Carbamazepine 173-186 epoxide hydrolase 1 Homo sapiens 0-28 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. Carbamazepine 173-186 epoxide hydrolase 1 Homo sapiens 30-35 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. Epoxy Compounds 211-219 epoxide hydrolase 1 Homo sapiens 0-28 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. Epoxy Compounds 211-219 epoxide hydrolase 1 Homo sapiens 30-35 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. 1,3-butadiene 248-257 epoxide hydrolase 1 Homo sapiens 0-28 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. 1,3-butadiene 248-257 epoxide hydrolase 1 Homo sapiens 30-35 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. Benzene 259-266 epoxide hydrolase 1 Homo sapiens 0-28 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. Benzene 259-266 epoxide hydrolase 1 Homo sapiens 30-35 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. polyaromatic hydrocarbons 285-310 epoxide hydrolase 1 Homo sapiens 0-28 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. polyaromatic hydrocarbons 285-310 epoxide hydrolase 1 Homo sapiens 30-35 21825496-1 2009 Small angle x-ray scattering (SAXS) in a poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV) solution has shown the important role of pi-electron conjugation in controlling the chain conformation and assembly. poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] 41-101 epoxide hydrolase 1 Homo sapiens 103-106 19017876-8 2009 In probands from the Boston Early-Onset COPD Study, SNPs in EPHX1 and in SERPINE2 were associated with the requirement for supplemental oxygen. Oxygen 136-142 epoxide hydrolase 1 Homo sapiens 60-65 19143498-0 2009 Modeling the dynamics of chromophores in conjugated polymers: the case of poly(2-methoxy-5-(2"-ethylhexyl)oxy 1,4-phenylene vinylene) (MEH-PPV). Polymers 52-60 epoxide hydrolase 1 Homo sapiens 135-138 19143498-0 2009 Modeling the dynamics of chromophores in conjugated polymers: the case of poly(2-methoxy-5-(2"-ethylhexyl)oxy 1,4-phenylene vinylene) (MEH-PPV). poly(2-methoxy-5-(2"-ethylhexyl)oxy 1,4-phenylene vinylene) 74-133 epoxide hydrolase 1 Homo sapiens 135-138 19143498-1 2009 By combining force-field approaches to quantum-chemical techniques, we have explored the influence of conformational changes on the nature of the lowest electronic excitations in model chains of poly(2-methoxy-5-(2"-ethylhexyl)oxy 1,4-phenylene vinylene) (MEH-PPV). poly(2-methoxy-5-(2"-ethylhexyl)oxy 1,4-phenylene vinylene) 195-254 epoxide hydrolase 1 Homo sapiens 256-259 19156770-1 2009 The present report describes the use of MEKC in the presence of 35 mM sodium tetraborate, pH 9.0, containing 60 mM SDS for the complete separation and identification of creatinine, 1-methylhistidine (1-MeH) and 3-MeH in human urine. sodium borate 70-88 epoxide hydrolase 1 Homo sapiens 213-216 19156770-1 2009 The present report describes the use of MEKC in the presence of 35 mM sodium tetraborate, pH 9.0, containing 60 mM SDS for the complete separation and identification of creatinine, 1-methylhistidine (1-MeH) and 3-MeH in human urine. Creatinine 169-179 epoxide hydrolase 1 Homo sapiens 213-216 19721221-3 2009 We designed and synthesized a resorufin-based fluorogenic probe, 7-(2-(oxiran-2-yl)ethoxy) resorufin, which was hydrolyzed by microsomal epoxide hydrolase to form the corresponding diol, which upon further treatment with sodium periodate released the strongly fluorescent resorufin. resorufin 30-39 epoxide hydrolase 1 Homo sapiens 126-154 19721221-3 2009 We designed and synthesized a resorufin-based fluorogenic probe, 7-(2-(oxiran-2-yl)ethoxy) resorufin, which was hydrolyzed by microsomal epoxide hydrolase to form the corresponding diol, which upon further treatment with sodium periodate released the strongly fluorescent resorufin. 7-(2-(oxiran-2-yl)ethoxy) resorufin 65-100 epoxide hydrolase 1 Homo sapiens 126-154 19721221-3 2009 We designed and synthesized a resorufin-based fluorogenic probe, 7-(2-(oxiran-2-yl)ethoxy) resorufin, which was hydrolyzed by microsomal epoxide hydrolase to form the corresponding diol, which upon further treatment with sodium periodate released the strongly fluorescent resorufin. diol 181-185 epoxide hydrolase 1 Homo sapiens 126-154 19721221-3 2009 We designed and synthesized a resorufin-based fluorogenic probe, 7-(2-(oxiran-2-yl)ethoxy) resorufin, which was hydrolyzed by microsomal epoxide hydrolase to form the corresponding diol, which upon further treatment with sodium periodate released the strongly fluorescent resorufin. metaperiodate 221-237 epoxide hydrolase 1 Homo sapiens 126-154 19721221-3 2009 We designed and synthesized a resorufin-based fluorogenic probe, 7-(2-(oxiran-2-yl)ethoxy) resorufin, which was hydrolyzed by microsomal epoxide hydrolase to form the corresponding diol, which upon further treatment with sodium periodate released the strongly fluorescent resorufin. resorufin 91-100 epoxide hydrolase 1 Homo sapiens 126-154 19321813-8 2009 Addition of an EPHX1 inhibitor, cyclohexene oxide (CHO) or 1,1,1-trichloropropene 2,3-oxide (TCPO), to the culture medium increased intracellular and extracellular ROS levels of OE-E6/E7 cells and suppressed the beneficial effect of the cells on embryo development; CHO and TCPO at these concentrations had no adverse effect on OE-E6/E7 growth and embryo development in vitro. cyclohexene oxide 32-49 epoxide hydrolase 1 Homo sapiens 15-20 19321813-8 2009 Addition of an EPHX1 inhibitor, cyclohexene oxide (CHO) or 1,1,1-trichloropropene 2,3-oxide (TCPO), to the culture medium increased intracellular and extracellular ROS levels of OE-E6/E7 cells and suppressed the beneficial effect of the cells on embryo development; CHO and TCPO at these concentrations had no adverse effect on OE-E6/E7 growth and embryo development in vitro. Reactive Oxygen Species 164-167 epoxide hydrolase 1 Homo sapiens 15-20 19321813-8 2009 Addition of an EPHX1 inhibitor, cyclohexene oxide (CHO) or 1,1,1-trichloropropene 2,3-oxide (TCPO), to the culture medium increased intracellular and extracellular ROS levels of OE-E6/E7 cells and suppressed the beneficial effect of the cells on embryo development; CHO and TCPO at these concentrations had no adverse effect on OE-E6/E7 growth and embryo development in vitro. Trichloroepoxypropane 274-278 epoxide hydrolase 1 Homo sapiens 15-20 19620853-0 2009 Genetic variants in microsomal epoxide hydrolase influence carbamazepine dosing. Carbamazepine 59-72 epoxide hydrolase 1 Homo sapiens 20-48 19620853-8 2009 However, a multivariate model, incorporating patient age and specific genotypes (c.337T>C, c.416A>G) of the EPHX1 gene encoding microsomal epoxide hydrolase, revealed a significant association with the maintenance dose of carbamazepine (r(2) = 0.362, P= 0.002). Carbamazepine 228-241 epoxide hydrolase 1 Homo sapiens 114-119 19620853-8 2009 However, a multivariate model, incorporating patient age and specific genotypes (c.337T>C, c.416A>G) of the EPHX1 gene encoding microsomal epoxide hydrolase, revealed a significant association with the maintenance dose of carbamazepine (r(2) = 0.362, P= 0.002). Carbamazepine 228-241 epoxide hydrolase 1 Homo sapiens 134-162 19620853-9 2009 CONCLUSIONS: This proof-of-principle study suggests that genetic variants in EPHX1 can be used to predict maintenance doses of carbamazepine. Carbamazepine 127-140 epoxide hydrolase 1 Homo sapiens 77-82 19456168-0 2009 Complex nanoparticle of light-emitting MEH-PPV with Au: enhanced luminescence. Gold 52-54 epoxide hydrolase 1 Homo sapiens 39-42 19456168-1 2009 Complex nanoparticles (NPs) of poly(2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene) (MEH-PPV) NP adsorbed with Au NPs (MEH-PPV/Au NPs) were fabricated through a reprecipitation method. poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 31-88 epoxide hydrolase 1 Homo sapiens 90-93 19456168-1 2009 Complex nanoparticles (NPs) of poly(2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene) (MEH-PPV) NP adsorbed with Au NPs (MEH-PPV/Au NPs) were fabricated through a reprecipitation method. poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 31-88 epoxide hydrolase 1 Homo sapiens 124-127 19456168-3 2009 The laser confocal microscope photoluminescence (PL) efficiency of the complex MEH-PPV/Au single NP dramatically increased compared with that of the MEH-PPV single NP without Au NPs, which was directly confirmed through color charge-coupled device images. Gold 87-89 epoxide hydrolase 1 Homo sapiens 79-82 19456168-3 2009 The laser confocal microscope photoluminescence (PL) efficiency of the complex MEH-PPV/Au single NP dramatically increased compared with that of the MEH-PPV single NP without Au NPs, which was directly confirmed through color charge-coupled device images. Gold 175-177 epoxide hydrolase 1 Homo sapiens 79-82 19456168-5 2009 The strong local field enhancement due to nanogaps between Au NPs in the background of a light-emitting MEH-PPV NP might be another origin of the PL enhancement of the NP complex, as supported by finite difference time domain calculations. Gold 59-61 epoxide hydrolase 1 Homo sapiens 104-107 19456168-5 2009 The strong local field enhancement due to nanogaps between Au NPs in the background of a light-emitting MEH-PPV NP might be another origin of the PL enhancement of the NP complex, as supported by finite difference time domain calculations. pl 146-148 epoxide hydrolase 1 Homo sapiens 104-107 19532918-1 2009 Excellent control in the synthesis of MEH-PPV can be achieved by microwave assisted, ring-opening metathesis polymerisation (ROMP) of [2.2]paracyclophanedienes. [2.2]paracyclophanedienes 134-159 epoxide hydrolase 1 Homo sapiens 38-41 19260669-2 2009 Extensive new fluorescence-voltage single molecule spectroscopy (FV-SMS) measurements were performed on single chains of the archetypical conjugated polymer MEH-PPV embedded in a capacitor device to complement previous studies of the influence of the bias scan rate and optical excitation intensity. Polymers 149-156 epoxide hydrolase 1 Homo sapiens 157-160 19185127-0 2009 Langmuir-Blodgett film based on MEH-PPV for cholesterol biosensor. Cholesterol 44-55 epoxide hydrolase 1 Homo sapiens 32-35 19185127-1 2009 Cholesterol oxidase (ChOx) has been immobilized onto conducting poly[2-methoxy,5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV)/stearic acid (SA) Langmuir-Blodgett film transferred onto octadecanethiol (ODT) modified gold plate. poly[2-methoxy,5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] 64-124 epoxide hydrolase 1 Homo sapiens 126-129 19127076-4 2009 In the hypersensitive patient, 2 genetic factors previously associated with intolerance to carbamazepine were detected: the allele HLA-A*3101 and homozygosity for the variant allele of SNP rs1051740 in EPHX1. Carbamazepine 91-104 epoxide hydrolase 1 Homo sapiens 202-207 18784359-8 2008 In addition, we found that alcohol drinkers with the EPHX1 rs3738047 GA + AA genotypes and non-alcohol drinkers with the GSTP1 rs1695 AA genotype tended to be more susceptible to benzene toxicity. Alcohols 27-34 epoxide hydrolase 1 Homo sapiens 53-58 21832764-0 2008 Traps and performance of MEH-PPV/CdSe(ZnS) nanocomposite-based organic light-emitting diodes. cdse 33-37 epoxide hydrolase 1 Homo sapiens 25-28 21832764-0 2008 Traps and performance of MEH-PPV/CdSe(ZnS) nanocomposite-based organic light-emitting diodes. Zinc 38-41 epoxide hydrolase 1 Homo sapiens 25-28 21832764-1 2008 We report the fabrication and investigations of organic light-emitting diodes (OLEDs) using a composite made by mixing poly[2-methoxy-5(2"-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) with CdSe/ZnS core/shell quantum dots (QDs). poly[2-methoxy-5(2"-ethylhexyloxy)-1,4-phenylenevinylene] 119-176 epoxide hydrolase 1 Homo sapiens 178-181 18680736-8 2008 CONCLUSION: A multiple regression model based on the genetic polymorphisms of VKORC1, CYP2C9, EPHX1 and the non-genetic factors of age and body weight can explain 40.2% of the variance in warfarin dose in Han Chinese patients. Warfarin 188-196 epoxide hydrolase 1 Homo sapiens 94-99 18842009-2 2008 After excitation of the CTC band, an immediate (<100 fs) electron transfer is observed from the polymer chain to the acceptor with the same yield as in the MEH-PPV/PCBM blend. Polymers 99-106 epoxide hydrolase 1 Homo sapiens 159-162 18842009-2 2008 After excitation of the CTC band, an immediate (<100 fs) electron transfer is observed from the polymer chain to the acceptor with the same yield as in the MEH-PPV/PCBM blend. PCBM 167-171 epoxide hydrolase 1 Homo sapiens 159-162 18811882-3 2008 Based chi on the polymorphisms of EPHX1 gene (tyrosine/histidine 113, histidine/arginine 139), the population can be classified into four groups of putative EPHX1 phenotypes (fast, normal, slow and very slow). Tyrosine 46-54 epoxide hydrolase 1 Homo sapiens 34-39 18811882-3 2008 Based chi on the polymorphisms of EPHX1 gene (tyrosine/histidine 113, histidine/arginine 139), the population can be classified into four groups of putative EPHX1 phenotypes (fast, normal, slow and very slow). Histidine 55-64 epoxide hydrolase 1 Homo sapiens 34-39 18811882-3 2008 Based chi on the polymorphisms of EPHX1 gene (tyrosine/histidine 113, histidine/arginine 139), the population can be classified into four groups of putative EPHX1 phenotypes (fast, normal, slow and very slow). Histidine 70-79 epoxide hydrolase 1 Homo sapiens 34-39 18842009-4 2008 For comparison, the recombination efficiency obtained in the MEH-PPV/PCBM blend does not exceed a mere 50%. PCBM 69-73 epoxide hydrolase 1 Homo sapiens 61-64 18842009-6 2008 In contrast, in the MEH-PPV/PCBM blend the dipole moment orientation of the charge-induced transition is less correlated with the polarization of the excitation photon. PCBM 28-32 epoxide hydrolase 1 Homo sapiens 20-23 18842009-7 2008 According to these data, photogeneration and recombination of charges in the CTCs take place locally (i.e., within a single pair of a polymer conjugation segment and an acceptor) while in the MEH-PPV/PCBM blend exciton migration precedes the separation of charges. Polymers 134-141 epoxide hydrolase 1 Homo sapiens 192-195 18842009-7 2008 According to these data, photogeneration and recombination of charges in the CTCs take place locally (i.e., within a single pair of a polymer conjugation segment and an acceptor) while in the MEH-PPV/PCBM blend exciton migration precedes the separation of charges. PCBM 200-204 epoxide hydrolase 1 Homo sapiens 192-195 18842009-8 2008 Results of the ultrafast experiments are supported by photocurrent measurements on the corresponding MEH-PPV/acceptor photodiodes. photodiodes 118-129 epoxide hydrolase 1 Homo sapiens 101-104 18614560-3 2008 To date, most reported findings have been for EPHX1, particularly in relation to functional variants associated with fast and slow metabolism of epoxide intermediates. Epoxy Compounds 145-152 epoxide hydrolase 1 Homo sapiens 46-51 18710232-2 2008 Using ensemble absorption polarization spectroscopy together with single molecule fluorescence polarization measurements, we have determined the order parameter of the conjugated polymer MEH-PPV (poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene]) in the liquid crystal 5CB (4-cyano-4-n-pentylbiphenyl) as a function of polymer chain length. poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene 196-255 epoxide hydrolase 1 Homo sapiens 187-190 18710232-2 2008 Using ensemble absorption polarization spectroscopy together with single molecule fluorescence polarization measurements, we have determined the order parameter of the conjugated polymer MEH-PPV (poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene]) in the liquid crystal 5CB (4-cyano-4-n-pentylbiphenyl) as a function of polymer chain length. 4-cyano-4'-pentylbiphenyl 280-283 epoxide hydrolase 1 Homo sapiens 187-190 18729401-1 2008 A coarse-grained (CG) model and Langevin dynamics scheme are proposed to investigate the material properties in dilute solution of a model semiconducting conjugated polymer, poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene) (MEH-PPV). poly(2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylenevinylene) 174-232 epoxide hydrolase 1 Homo sapiens 234-237 18710232-2 2008 Using ensemble absorption polarization spectroscopy together with single molecule fluorescence polarization measurements, we have determined the order parameter of the conjugated polymer MEH-PPV (poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene]) in the liquid crystal 5CB (4-cyano-4-n-pentylbiphenyl) as a function of polymer chain length. 4-cyano-4'-pentylbiphenyl 285-312 epoxide hydrolase 1 Homo sapiens 187-190 18710232-2 2008 Using ensemble absorption polarization spectroscopy together with single molecule fluorescence polarization measurements, we have determined the order parameter of the conjugated polymer MEH-PPV (poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene]) in the liquid crystal 5CB (4-cyano-4-n-pentylbiphenyl) as a function of polymer chain length. Polymers 179-186 epoxide hydrolase 1 Homo sapiens 187-190 18247500-1 2008 We present the first measurement of the buried surface electronic states of the conjugated polymer poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylenevinylene] (MEH-PPV) using two-dimensional (2D) IR-visible sum frequency generation (SFG). Polymers 91-98 epoxide hydrolase 1 Homo sapiens 160-163 19093542-10 2008 Firstly, we respectively prepared the devices with the polymer MEH-PPV and SiO2, and ZnS, and ZnO, and found that SiO2/ZnS and ZnO/SiO2 are better. Silicon Dioxide 114-118 epoxide hydrolase 1 Homo sapiens 63-66 19093542-10 2008 Firstly, we respectively prepared the devices with the polymer MEH-PPV and SiO2, and ZnS, and ZnO, and found that SiO2/ZnS and ZnO/SiO2 are better. Silicon Dioxide 114-118 epoxide hydrolase 1 Homo sapiens 63-66 18646814-1 2008 Fluorescence emission and excitation spectra of single MEH-PPV polymer molecules dispersed in thin PMMA films have been recorded at 1.2 and 20 K. We observe single as well as multichromophore emission in single chain emission spectra, whereby the relative fractions depend on the two different molecular weights (50 and 350 kDa) studied. Polymers 63-70 epoxide hydrolase 1 Homo sapiens 55-58 18646814-1 2008 Fluorescence emission and excitation spectra of single MEH-PPV polymer molecules dispersed in thin PMMA films have been recorded at 1.2 and 20 K. We observe single as well as multichromophore emission in single chain emission spectra, whereby the relative fractions depend on the two different molecular weights (50 and 350 kDa) studied. Polymethyl Methacrylate 99-103 epoxide hydrolase 1 Homo sapiens 55-58 18646814-7 2008 In accordance with earlier literature data it is argued that linear electron-phonon coupling should be quite strong for MEH-PPV in PMMA, leading to only a small fraction of chromophores exhibiting zero-phonon lines. Polymethyl Methacrylate 131-135 epoxide hydrolase 1 Homo sapiens 120-123 18561348-4 2008 The red-emitting conjugated polymer, MEH-PPV, is confined to the interlayer space of layered SnS(2). Polymers 28-35 epoxide hydrolase 1 Homo sapiens 37-40 18561348-9 2008 The PL spectra of the MEH-PPV incorporated SnS(2) nanocomposites using the different solvents are in good agreement with the PL spectra of the same solutions, indicating that the conformation of the polymer chains in the solutions is retained upon intercalation into the inorganic host. Polymers 199-206 epoxide hydrolase 1 Homo sapiens 22-25 18517256-3 2008 After sectioning the multilayer film, dissolution of the BBL with methanesulfonic acid yielded uniaxially aligned MEH-PPV nanowires with rectangular cross sections, and etching MEH-PPV with an oxygen plasma yielded BBL nanowires. N-Carbobenzyloxy-L-alanine 57-60 epoxide hydrolase 1 Homo sapiens 114-117 18517256-3 2008 After sectioning the multilayer film, dissolution of the BBL with methanesulfonic acid yielded uniaxially aligned MEH-PPV nanowires with rectangular cross sections, and etching MEH-PPV with an oxygen plasma yielded BBL nanowires. N-Carbobenzyloxy-L-alanine 215-218 epoxide hydrolase 1 Homo sapiens 177-180 18425322-8 2008 In addition, increased risk for HNC was associated consistently with the ALDH2*1/*2, p53 codon 72 Pro/Pro and EPHX1 codon 113 Tyr/His and His/His genotypes. Tyrosine 126-129 epoxide hydrolase 1 Homo sapiens 110-115 18331112-1 2008 The temperature dependence of the photoluminescence properties of a thin film of poly[2-methoxy-5-(2(")-ethylhexyloxy)-p-phenylene-vinylene], MEH-PPV, fabricated by spin coating, is analyzed. poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 81-139 epoxide hydrolase 1 Homo sapiens 142-145 18468150-1 2008 Electroluminescence was obtained from an indium-tin-oxide/poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV): ZnSe/2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline (BCP)/ 8-tris-hydroxyquinoline (Alq3)/LiF/Al structured device, in which ZnSe nanocrystals were synthesized in aqueous solution by using mercapto-acetate acid as stabilizer. indium tin oxide 41-57 epoxide hydrolase 1 Homo sapiens 119-122 18468150-1 2008 Electroluminescence was obtained from an indium-tin-oxide/poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV): ZnSe/2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline (BCP)/ 8-tris-hydroxyquinoline (Alq3)/LiF/Al structured device, in which ZnSe nanocrystals were synthesized in aqueous solution by using mercapto-acetate acid as stabilizer. poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] 58-117 epoxide hydrolase 1 Homo sapiens 119-122 18468150-1 2008 Electroluminescence was obtained from an indium-tin-oxide/poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV): ZnSe/2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline (BCP)/ 8-tris-hydroxyquinoline (Alq3)/LiF/Al structured device, in which ZnSe nanocrystals were synthesized in aqueous solution by using mercapto-acetate acid as stabilizer. Selanylidenezinc 129-133 epoxide hydrolase 1 Homo sapiens 119-122 18468150-1 2008 Electroluminescence was obtained from an indium-tin-oxide/poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV): ZnSe/2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline (BCP)/ 8-tris-hydroxyquinoline (Alq3)/LiF/Al structured device, in which ZnSe nanocrystals were synthesized in aqueous solution by using mercapto-acetate acid as stabilizer. bathocuproine 134-179 epoxide hydrolase 1 Homo sapiens 119-122 18468150-1 2008 Electroluminescence was obtained from an indium-tin-oxide/poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV): ZnSe/2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline (BCP)/ 8-tris-hydroxyquinoline (Alq3)/LiF/Al structured device, in which ZnSe nanocrystals were synthesized in aqueous solution by using mercapto-acetate acid as stabilizer. bathocuproine 181-184 epoxide hydrolase 1 Homo sapiens 119-122 18468150-1 2008 Electroluminescence was obtained from an indium-tin-oxide/poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV): ZnSe/2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline (BCP)/ 8-tris-hydroxyquinoline (Alq3)/LiF/Al structured device, in which ZnSe nanocrystals were synthesized in aqueous solution by using mercapto-acetate acid as stabilizer. 8-tris-hydroxyquinoline 187-210 epoxide hydrolase 1 Homo sapiens 119-122 18468150-1 2008 Electroluminescence was obtained from an indium-tin-oxide/poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV): ZnSe/2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline (BCP)/ 8-tris-hydroxyquinoline (Alq3)/LiF/Al structured device, in which ZnSe nanocrystals were synthesized in aqueous solution by using mercapto-acetate acid as stabilizer. tris-(8-hydroxyquinoline)aluminum 212-216 epoxide hydrolase 1 Homo sapiens 119-122 18468150-1 2008 Electroluminescence was obtained from an indium-tin-oxide/poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV): ZnSe/2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline (BCP)/ 8-tris-hydroxyquinoline (Alq3)/LiF/Al structured device, in which ZnSe nanocrystals were synthesized in aqueous solution by using mercapto-acetate acid as stabilizer. Aluminum 212-214 epoxide hydrolase 1 Homo sapiens 119-122 18468150-1 2008 Electroluminescence was obtained from an indium-tin-oxide/poly[2-methoxy-5-(2"-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV): ZnSe/2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline (BCP)/ 8-tris-hydroxyquinoline (Alq3)/LiF/Al structured device, in which ZnSe nanocrystals were synthesized in aqueous solution by using mercapto-acetate acid as stabilizer. mercapto-acetate acid 317-338 epoxide hydrolase 1 Homo sapiens 119-122 18468150-3 2008 The photoluminescence and electroluminescence spectra changed with the mass ratio of ZnSe to MEH-PPV in the composite. Selanylidenezinc 85-89 epoxide hydrolase 1 Homo sapiens 93-96 18311961-1 2008 Thin spin-cast films of poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylenevinylene] (MEH-PPV) were prepared from samples whose weight-average molecular weight (Mw) was varied in the range of 10-1600 kg/mol. poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylenevinylene] 24-83 epoxide hydrolase 1 Homo sapiens 85-88 17544214-0 2008 Electric force microscopy investigation of a MEH-PPV conjugated polymer blend: robustness or frailty? Polymers 64-71 epoxide hydrolase 1 Homo sapiens 45-48 17544214-1 2008 Electric force microscopy (EFM) was employed in the electrical characterization of a blend of thermoplastic polyurethane (TPU) and poly(2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylenevinylene) (MEH-PPV) conjugated polymer. poly(2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylenevinylene) 131-190 epoxide hydrolase 1 Homo sapiens 192-195 18247500-1 2008 We present the first measurement of the buried surface electronic states of the conjugated polymer poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylenevinylene] (MEH-PPV) using two-dimensional (2D) IR-visible sum frequency generation (SFG). poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylenevinylene] 99-158 epoxide hydrolase 1 Homo sapiens 160-163 18247500-2 2008 SFG electronic spectra were obtained by scanning the frequencies of both incident visible and IR beams and used to study the surface electronic transitions associated with the C-C stretching of benzene rings located at the backbone of MEH-PPV. Benzene 194-201 epoxide hydrolase 1 Homo sapiens 235-238 18478996-3 2008 A surfactant was used to transfer the nanocrystals from the aqueous solution to organic solvent, so that ZnSe and MEH-PPV could be mixed sufficiently and were used as an emitting layer in a multilayered electroluminescence device: Glass/ITO/MEH-PPV : ZnSe /BCP/Alq3/LiF/Al. Aluminum 261-263 epoxide hydrolase 1 Homo sapiens 114-117 18478996-3 2008 A surfactant was used to transfer the nanocrystals from the aqueous solution to organic solvent, so that ZnSe and MEH-PPV could be mixed sufficiently and were used as an emitting layer in a multilayered electroluminescence device: Glass/ITO/MEH-PPV : ZnSe /BCP/Alq3/LiF/Al. Selanylidenezinc 105-109 epoxide hydrolase 1 Homo sapiens 241-244 18478996-4 2008 A comparison between absorption spectra and photoluminescence spectra of ZnSe nanocrystals and MEH-PPV thin film exhibits an effective energy transfer from ZnSe nanocrystals to MEH-PPV, which is one reason for the existing difference between photoluminescence spectrum and electroluminescence spectrum of MEH-PPV : ZnSe nanocomposite film. Selanylidenezinc 73-77 epoxide hydrolase 1 Homo sapiens 177-180 18478996-3 2008 A surfactant was used to transfer the nanocrystals from the aqueous solution to organic solvent, so that ZnSe and MEH-PPV could be mixed sufficiently and were used as an emitting layer in a multilayered electroluminescence device: Glass/ITO/MEH-PPV : ZnSe /BCP/Alq3/LiF/Al. Selanylidenezinc 251-255 epoxide hydrolase 1 Homo sapiens 114-117 18478996-3 2008 A surfactant was used to transfer the nanocrystals from the aqueous solution to organic solvent, so that ZnSe and MEH-PPV could be mixed sufficiently and were used as an emitting layer in a multilayered electroluminescence device: Glass/ITO/MEH-PPV : ZnSe /BCP/Alq3/LiF/Al. bcp 257-260 epoxide hydrolase 1 Homo sapiens 114-117 18478996-3 2008 A surfactant was used to transfer the nanocrystals from the aqueous solution to organic solvent, so that ZnSe and MEH-PPV could be mixed sufficiently and were used as an emitting layer in a multilayered electroluminescence device: Glass/ITO/MEH-PPV : ZnSe /BCP/Alq3/LiF/Al. tris-(8-hydroxyquinoline)aluminum 261-265 epoxide hydrolase 1 Homo sapiens 114-117 18478996-4 2008 A comparison between absorption spectra and photoluminescence spectra of ZnSe nanocrystals and MEH-PPV thin film exhibits an effective energy transfer from ZnSe nanocrystals to MEH-PPV, which is one reason for the existing difference between photoluminescence spectrum and electroluminescence spectrum of MEH-PPV : ZnSe nanocomposite film. Selanylidenezinc 73-77 epoxide hydrolase 1 Homo sapiens 177-180 17711870-1 2007 BACKGROUND: Microsomal epoxide hydrolase (EPHX1) metabolises xenobiotics including polyaromatic hydrocarbons (PAHs). polyaromatic hydrocarbons 83-108 epoxide hydrolase 1 Homo sapiens 12-40 18179197-4 2008 The absorbance spectra of poly(2-methoxy-5-(2-ethylhexyloxy))-1,4-phenylenevinylene (MEH-PPV) and BTCD-60 indicated that the films obtained from polymers that were dissolved in aromatic solvents such as toluene were found to possess more pi-stacking as compared to that of films obtained from a good solvent such as THF. poly(2-methoxy-5-(2-ethylhexyloxy))-1,4-phenylenevinylene 26-83 epoxide hydrolase 1 Homo sapiens 85-88 18179197-4 2008 The absorbance spectra of poly(2-methoxy-5-(2-ethylhexyloxy))-1,4-phenylenevinylene (MEH-PPV) and BTCD-60 indicated that the films obtained from polymers that were dissolved in aromatic solvents such as toluene were found to possess more pi-stacking as compared to that of films obtained from a good solvent such as THF. 3-azido-2,7-naphthalene disulfonate 94-97 epoxide hydrolase 1 Homo sapiens 85-88 18179197-6 2008 Concentration dependent excitation spectra of the polymers confirmed the presence of aggregated polymer chains in MEH-PPV, which is the main reason for the quenching of luminescence intensity in the polymer. Polymers 50-58 epoxide hydrolase 1 Homo sapiens 114-117 18179197-6 2008 Concentration dependent excitation spectra of the polymers confirmed the presence of aggregated polymer chains in MEH-PPV, which is the main reason for the quenching of luminescence intensity in the polymer. Polymers 50-57 epoxide hydrolase 1 Homo sapiens 114-117 18179197-7 2008 Solvent induced aggregation studies of polymers in THF and methanol mixture further supports the existence of strong aggregation in MEH-PPV as compared to that of bulky BTCD-60. tetrahydrofuran 51-54 epoxide hydrolase 1 Homo sapiens 132-135 18179197-7 2008 Solvent induced aggregation studies of polymers in THF and methanol mixture further supports the existence of strong aggregation in MEH-PPV as compared to that of bulky BTCD-60. Methanol 59-67 epoxide hydrolase 1 Homo sapiens 132-135 18283809-1 2007 The carrier transport capability and luminescence efficiency of poly(2-methoxy-5-(2-ethyl hexyloxy)-p-phenylene vinylene) (MEH-PPV) films are enhanced by doping with dehydrated nanotubed titanic acid (DNTA). poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) 64-121 epoxide hydrolase 1 Homo sapiens 123-126 18283809-1 2007 The carrier transport capability and luminescence efficiency of poly(2-methoxy-5-(2-ethyl hexyloxy)-p-phenylene vinylene) (MEH-PPV) films are enhanced by doping with dehydrated nanotubed titanic acid (DNTA). titanium hydroxide 187-199 epoxide hydrolase 1 Homo sapiens 123-126 18283809-1 2007 The carrier transport capability and luminescence efficiency of poly(2-methoxy-5-(2-ethyl hexyloxy)-p-phenylene vinylene) (MEH-PPV) films are enhanced by doping with dehydrated nanotubed titanic acid (DNTA). dnta 201-205 epoxide hydrolase 1 Homo sapiens 123-126 18283809-2 2007 MEH-PPV molecules, either wrapped on the outer surface of or encapsulated into DNTA pores, have a more open, straighter conformation than undoped molecules, which induces a longer conjugated backbone and stronger interchain interactions, thereby, enhancing carrier mobility. dnta 79-83 epoxide hydrolase 1 Homo sapiens 0-3 17975912-2 2008 The polymer solute is poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] (or MEH-PPV), and the LC solvent is 5CB. Polymers 4-11 epoxide hydrolase 1 Homo sapiens 87-90 17975912-8 2008 Furthermore, our results suggest that conjugated polymers such as MEH-PPV can be used as sensitive local probes to explore complex (and unknown) structures in anisotropic media. Polymers 49-57 epoxide hydrolase 1 Homo sapiens 66-69 17994663-5 2007 The fast component in the fluorescence decays of MEH-PPV polymers (PPVs), is assigned to resonance energy transfer from short to longer polymer segments. ppvs 67-71 epoxide hydrolase 1 Homo sapiens 49-52 17994663-5 2007 The fast component in the fluorescence decays of MEH-PPV polymers (PPVs), is assigned to resonance energy transfer from short to longer polymer segments. Polymers 57-64 epoxide hydrolase 1 Homo sapiens 49-52 18093316-8 2007 For the high-risk adenomas this positive association was more obvious for the common allele (Tyr allele) of the EPHX1 codon 113 polymorphism. Tyrosine 93-96 epoxide hydrolase 1 Homo sapiens 112-117 17711870-1 2007 BACKGROUND: Microsomal epoxide hydrolase (EPHX1) metabolises xenobiotics including polyaromatic hydrocarbons (PAHs). polyaromatic hydrocarbons 83-108 epoxide hydrolase 1 Homo sapiens 42-47 17711870-1 2007 BACKGROUND: Microsomal epoxide hydrolase (EPHX1) metabolises xenobiotics including polyaromatic hydrocarbons (PAHs). pahs 110-114 epoxide hydrolase 1 Homo sapiens 12-40 17711870-1 2007 BACKGROUND: Microsomal epoxide hydrolase (EPHX1) metabolises xenobiotics including polyaromatic hydrocarbons (PAHs). pahs 110-114 epoxide hydrolase 1 Homo sapiens 42-47 17711870-3 2007 The effects of EPHX1 variants may depend upon exposures from tobacco smoke and traffic emissions that contain PAHs as well as variants in other enzymes in the PAH metabolic pathway such as glutathione S-transferase (GST) genes. pahs 110-114 epoxide hydrolase 1 Homo sapiens 15-20 17711870-3 2007 The effects of EPHX1 variants may depend upon exposures from tobacco smoke and traffic emissions that contain PAHs as well as variants in other enzymes in the PAH metabolic pathway such as glutathione S-transferase (GST) genes. p-Aminohippuric Acid 110-113 epoxide hydrolase 1 Homo sapiens 15-20 17711870-4 2007 A study was undertaken to investigate associations of variants in EPHX1, GSTM1, GSTP1 and GSTT1 with asthma and the relationships between asthma, EPHX1 metabolic phenotypes and exposure to sources of PAHs. pahs 200-204 epoxide hydrolase 1 Homo sapiens 146-151 17867778-1 2007 Intermolecular donor-acceptor charge transfer complex (CTC) formed in the electronic ground state between poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) and 2,4,7-trinitrofluorenone (TNF) has been investigated by Raman and optical absorption spectroscopies. poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] 106-163 epoxide hydrolase 1 Homo sapiens 165-168 17822822-7 2007 Low-dose experiments indicate that the up-regulation of epoxide hydrolase 1 represents the most sensitive transcriptional biomarker of glycidamide exposure. glycidamide 135-146 epoxide hydrolase 1 Homo sapiens 56-75 17560029-4 2007 More specifically, we have employed the variable-force AFM method on organic mixtures, comprising a conjugated polymer (MEH-PPV) and an ion-conducting polymer electrolyte (PEO-XCF(3)SO(3), X=Li, K, Rb), and we demonstrate that it is capable of reversibly sampling such materials not only on the surface, but also (indirectly) in the topmost part of the bulk. Polymers 111-118 epoxide hydrolase 1 Homo sapiens 120-123 17927236-1 2007 The photoluminescence (PL) dynamics of poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV) blended in host polymer (polypropylene, PP) matrix as well as that in the neat film has been studied. poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] 39-99 epoxide hydrolase 1 Homo sapiens 101-104 17927236-1 2007 The photoluminescence (PL) dynamics of poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV) blended in host polymer (polypropylene, PP) matrix as well as that in the neat film has been studied. Polymers 126-133 epoxide hydrolase 1 Homo sapiens 101-104 17927236-1 2007 The photoluminescence (PL) dynamics of poly[2-methoxy-5-(2"-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV) blended in host polymer (polypropylene, PP) matrix as well as that in the neat film has been studied. Polypropylenes 135-148 epoxide hydrolase 1 Homo sapiens 101-104 17927236-2 2007 The concentration of MEH-PPV in the PP blend is designed to be fairly low (0.01 wt %) in order to observe the intrinsic intrachain PL property of MEH-PPV in the solid state. pl 131-133 epoxide hydrolase 1 Homo sapiens 21-24 17927236-2 2007 The concentration of MEH-PPV in the PP blend is designed to be fairly low (0.01 wt %) in order to observe the intrinsic intrachain PL property of MEH-PPV in the solid state. pl 131-133 epoxide hydrolase 1 Homo sapiens 146-149 17927236-11 2007 Finally, based on an argument on the different magnitudes of Stokes shift between the blend sample and the neat film, we conclude that the PL of MEH-PPV in the neat film predominantly occurs at the site of interchain excitations via the interchain migration of excitons. pl 139-141 epoxide hydrolase 1 Homo sapiens 145-148 17867778-1 2007 Intermolecular donor-acceptor charge transfer complex (CTC) formed in the electronic ground state between poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) and 2,4,7-trinitrofluorenone (TNF) has been investigated by Raman and optical absorption spectroscopies. 2,4,7-trinitrofluorenone 178-202 epoxide hydrolase 1 Homo sapiens 165-168 17867778-1 2007 Intermolecular donor-acceptor charge transfer complex (CTC) formed in the electronic ground state between poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) and 2,4,7-trinitrofluorenone (TNF) has been investigated by Raman and optical absorption spectroscopies. 2,4,7-trinitrofluorenone 204-207 epoxide hydrolase 1 Homo sapiens 165-168 17867778-5 2007 We suggest that polymer conjugated segments can form the CTC of variable composition MEH-PPV:TNF=1:X, where X<or=0.5 is per MEH-PPV monomer unit. Polymers 16-23 epoxide hydrolase 1 Homo sapiens 85-88 17867778-5 2007 We suggest that polymer conjugated segments can form the CTC of variable composition MEH-PPV:TNF=1:X, where X<or=0.5 is per MEH-PPV monomer unit. Polymers 16-23 epoxide hydrolase 1 Homo sapiens 127-130 17496169-5 2007 A strong association was found between genetic polymorphisms in six genes, including VKORC1, CYP2C9, PROC, EPHX1, GGCX, and ORM1, and interindividual variability in the anticoagulant effect of warfarin; the strongest predictors were VKORC1 and CYP2C9. Warfarin 193-201 epoxide hydrolase 1 Homo sapiens 107-112 17526865-5 2007 When results were stratified by maternal genotype, passive smoking conferred a significantly negative effect in the EPHX1 Tyr/His113 group (103.5 g, 95% CI: -205.8, -9.2) and in the His/His113 group (687.3 g, 95% CI: -748.3, -178.3). Tyrosine 122-125 epoxide hydrolase 1 Homo sapiens 116-121 17526865-5 2007 When results were stratified by maternal genotype, passive smoking conferred a significantly negative effect in the EPHX1 Tyr/His113 group (103.5 g, 95% CI: -205.8, -9.2) and in the His/His113 group (687.3 g, 95% CI: -748.3, -178.3). Histidine 126-129 epoxide hydrolase 1 Homo sapiens 116-121 21730411-5 2007 The markedly enhanced emission from MEH-PPV is experimentally observed in the composite polymer nanoparticles and attributed to Forster energy transfer from PVK to MEH-PPV for excitation at the absorption maximum of PVK. Polymers 88-95 epoxide hydrolase 1 Homo sapiens 36-39 21730411-5 2007 The markedly enhanced emission from MEH-PPV is experimentally observed in the composite polymer nanoparticles and attributed to Forster energy transfer from PVK to MEH-PPV for excitation at the absorption maximum of PVK. Polymers 88-95 epoxide hydrolase 1 Homo sapiens 164-167 17944393-1 2007 Polymer light-emitting diodes(PLEDs) devices based on MEH-PPV were fabricated. Polymers 0-7 epoxide hydrolase 1 Homo sapiens 54-57 24573875-0 2007 Association of the genetic polymorphism of EPHX1 and EPHX2 with the susceptibility to chronic benzene poisoning. Benzene 94-101 epoxide hydrolase 1 Homo sapiens 43-48 24573875-1 2007 The aim of this study was to explore the association of the genetic polymorphism of EPHX1 and EPHX2 with the susceptibility to chronic benzene poisoning (CBP). Benzene 135-142 epoxide hydrolase 1 Homo sapiens 84-89 24573875-1 2007 The aim of this study was to explore the association of the genetic polymorphism of EPHX1 and EPHX2 with the susceptibility to chronic benzene poisoning (CBP). 4,4'-Bis(N-carbazolyl)-1,1'-biphenyl 154-157 epoxide hydrolase 1 Homo sapiens 84-89 24573875-6 2007 It was also found that there were potential interactions between alcohol consumption and the polymorphism of EPHX1 rs1051741 (chiH (2) = 5.28, P = 0.02) or rs2234922 (chiH (2) = 6.71, P = 0.01). Alcohols 65-72 epoxide hydrolase 1 Homo sapiens 109-114 24573875-10 2007 The genetic polymorphism in EPHX1 may be associated with the risk of CBP in the Chinese occupational population and further research is needed for the association between the genetic polymorphism in EPHX2 and the susceptibility to CBP. 4,4'-Bis(N-carbazolyl)-1,1'-biphenyl 69-72 epoxide hydrolase 1 Homo sapiens 28-33