PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 15070437-2 2004 The cloning of human Zn transporters ZnT-like transporter 1 (hZTL1)/ZnT5 (SLC30A5) and hZIP4 (SLC39A4) were major advances in the understanding of the molecular mechanisms of dietary Zn absorption. Zinc 21-23 solute carrier family 30 member 5 Homo sapiens 61-66 15070437-2 2004 The cloning of human Zn transporters ZnT-like transporter 1 (hZTL1)/ZnT5 (SLC30A5) and hZIP4 (SLC39A4) were major advances in the understanding of the molecular mechanisms of dietary Zn absorption. Zinc 21-23 solute carrier family 30 member 5 Homo sapiens 68-72 15070437-2 2004 The cloning of human Zn transporters ZnT-like transporter 1 (hZTL1)/ZnT5 (SLC30A5) and hZIP4 (SLC39A4) were major advances in the understanding of the molecular mechanisms of dietary Zn absorption. Zinc 21-23 solute carrier family 30 member 5 Homo sapiens 74-81 15070437-4 2004 hZTL1 mediates Zn uptake when expressed in Xenopus laevis oocytes and hZIP4 is mutated in most cases of the inherited Zn deficiency disease acrodermatitis enteropathica. Zinc 15-17 solute carrier family 30 member 5 Homo sapiens 0-5 15070437-7 2004 Human intestinal Caco-2 cells show a similar response to increasing the Zn2+ concentration of the nutrient medium in relation to the expression of mRNA corresponding to several Zn transporters and that of ZnT1 (SLC30A1) and hZTL1/ZnT5 proteins. Zinc 72-76 solute carrier family 30 member 5 Homo sapiens 224-229 15070437-7 2004 Human intestinal Caco-2 cells show a similar response to increasing the Zn2+ concentration of the nutrient medium in relation to the expression of mRNA corresponding to several Zn transporters and that of ZnT1 (SLC30A1) and hZTL1/ZnT5 proteins. Zinc 72-76 solute carrier family 30 member 5 Homo sapiens 230-234 31852371-4 2020 The mRNA levels of ZnTs (ZnT5-7 & ZnT9), ZIPs (ZIP6-10, ZIP13-14), and MT were significantly (p < 0.05) higher in Saos-2 compared to THP-1 and RD. Zinc 19-23 solute carrier family 30 member 5 Homo sapiens 25-29 32598254-9 2021 After 24 hours, 2 mRNAs were characteristic for this time of incubation cells with salinomycin: TUFT1, MYD88 and after 48 hours, SLC30A5 could also be observed. salinomycin 83-94 solute carrier family 30 member 5 Homo sapiens 129-136 32051055-11 2020 Zinc chelate of hydroxy analogue of methionine increased Zn deposition in the jejunum and the relative mRNA expression of divalent metal transporters 1 and zinc transporter 5 in the duodenum (P < 0.05), indicating that Zn-HMTB may promote the absorption and transportation of Cd and Zn together by upregulating metal element transporters. Hydroxy Acids 16-23 solute carrier family 30 member 5 Homo sapiens 131-174 32051055-11 2020 Zinc chelate of hydroxy analogue of methionine increased Zn deposition in the jejunum and the relative mRNA expression of divalent metal transporters 1 and zinc transporter 5 in the duodenum (P < 0.05), indicating that Zn-HMTB may promote the absorption and transportation of Cd and Zn together by upregulating metal element transporters. Methionine 36-46 solute carrier family 30 member 5 Homo sapiens 131-174 11904301-7 2002 The hZnT-5-derived zinc transport activity was detected using the Golgi-enriched vesicles prepared from hZnT-5-induced HeLa/hZnT-5 cells in which exogenous hZnT-5 expression is inducible by the Tet-on gene regulation system. tetramethylenedisulfotetramine 194-197 solute carrier family 30 member 5 Homo sapiens 4-10 11904301-7 2002 The hZnT-5-derived zinc transport activity was detected using the Golgi-enriched vesicles prepared from hZnT-5-induced HeLa/hZnT-5 cells in which exogenous hZnT-5 expression is inducible by the Tet-on gene regulation system. tetramethylenedisulfotetramine 194-197 solute carrier family 30 member 5 Homo sapiens 104-110 11904301-7 2002 The hZnT-5-derived zinc transport activity was detected using the Golgi-enriched vesicles prepared from hZnT-5-induced HeLa/hZnT-5 cells in which exogenous hZnT-5 expression is inducible by the Tet-on gene regulation system. tetramethylenedisulfotetramine 194-197 solute carrier family 30 member 5 Homo sapiens 104-110 11904301-7 2002 The hZnT-5-derived zinc transport activity was detected using the Golgi-enriched vesicles prepared from hZnT-5-induced HeLa/hZnT-5 cells in which exogenous hZnT-5 expression is inducible by the Tet-on gene regulation system. tetramethylenedisulfotetramine 194-197 solute carrier family 30 member 5 Homo sapiens 104-110 28918363-4 2017 Chronic exposure to Zn accelerated senescence and untreated cells at later passages, where doubling time had increased, displayed relocation of labile Zn and altered expression of genes involved in the response to Zn toxicity, including SLC30A1, SLC39A6, SLC30A5, SLC30A10 and metallothioneins, indicating that senescent cells have altered zinc homeostasis. Zinc 20-22 solute carrier family 30 member 5 Homo sapiens 255-262 27833104-7 2016 Zn-exporters were found to be differentially expressed at the mRNA level, with a significant upregulation of SLC30A1, SLC30A9 and SLC30A10, and downregulation of SLC30A5 and SLC30A6 in PCa, compared to benign prostate. Zinc 0-2 solute carrier family 30 member 5 Homo sapiens 162-169 19245740-3 2009 The Zn transporter ZnT5 may play a key role in the absorption of dietary Zn. Zinc 4-6 solute carrier family 30 member 5 Homo sapiens 19-23 25582195-6 2015 Small interfering RNA (siRNA) targeted to ZNF658 abrogated the zinc-induced, ZTRE-dependent reduction in SLC30A5 (ZnT5 gene), SLC30A10 (ZnT10 gene), and CBWD transcripts in human Caco-2 cells and the ability of zinc to repress reporter gene expression from corresponding promoter-reporter constructs. ztre 77-81 solute carrier family 30 member 5 Homo sapiens 105-112 25582195-6 2015 Small interfering RNA (siRNA) targeted to ZNF658 abrogated the zinc-induced, ZTRE-dependent reduction in SLC30A5 (ZnT5 gene), SLC30A10 (ZnT10 gene), and CBWD transcripts in human Caco-2 cells and the ability of zinc to repress reporter gene expression from corresponding promoter-reporter constructs. ztre 77-81 solute carrier family 30 member 5 Homo sapiens 114-118 27303047-4 2016 In the present study, we found that the di-proline motif (PP-motif) in luminal loop 2 of ZnT5 and ZnT7 is important for TNAP activation. di-proline 40-50 solute carrier family 30 member 5 Homo sapiens 89-93 23811327-11 2013 Expression of the metal transport genes ZNT-1, ZNT-5, and ZIP-8 increased in CCT-LC cells culminating in reduced cadmium accumulation, suggesting adaptation to the metal. Metals 18-23 solute carrier family 30 member 5 Homo sapiens 47-52 23811327-11 2013 Expression of the metal transport genes ZNT-1, ZNT-5, and ZIP-8 increased in CCT-LC cells culminating in reduced cadmium accumulation, suggesting adaptation to the metal. Cadmium 113-120 solute carrier family 30 member 5 Homo sapiens 47-52 19366695-4 2009 Expression of ZnT5 was followed by both accelerated removal of Zn2+ from the cytoplasm and its increased vesicular sequestration. Zinc 63-67 solute carrier family 30 member 5 Homo sapiens 14-18 19245740-10 2009 This premise is being investigated by analysis of additional samples from a human adult cohort to test the hypothesis that methylation of the SLC30A5 promoter region contributes to the age-related decline in Zn status. Zinc 208-210 solute carrier family 30 member 5 Homo sapiens 142-149