PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
33131190-0	2021	Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans.	Sucrose	59-66	dual specificity phosphatase 8	Mus musculus	26-31
33131190-5	2021	RESULTS: Dusp8 KO mice showed a comparable preference for sucrose, but consumed more sucrose compared to WT mice.	Sucrose	58-65	dual specificity phosphatase 8	Mus musculus	9-14
33131190-5	2021	RESULTS: Dusp8 KO mice showed a comparable preference for sucrose, but consumed more sucrose compared to WT mice.	Sucrose	85-92	dual specificity phosphatase 8	Mus musculus	9-14
33131190-6	2021	In a progressive ratio task, Dusp8 KO females switched to a "trial and error" strategy to find sucrose while control Dusp8 WT mice kept their previously established seeking pattern.	Sucrose	95-102	dual specificity phosphatase 8	Mus musculus	29-34
33131190-9	2021	CONCLUSION: Our data suggest a novel role for Dusp8 in the perception of sweet high caloric food as well as in the control of sucrose consumption and foraging in mice and humans.	Sucrose	126-133	dual specificity phosphatase 8	Mus musculus	46-51
32780722-5	2020	Accordingly, global Jnk1 ablation, AAV-mediated Dusp8 overexpression in the mediobasal hypothalamus, or metyrapone-induced chemical adrenalectomy rescued the impaired glucose homeostasis of obese male Dusp8-KO mice, respectively.	Metyrapone	104-114	dual specificity phosphatase 8	Mus musculus	201-206
32780722-6	2020	The sex-specific role of murine Dusp8 in governing hypothalamic Jnk signaling, insulin sensitivity, and systemic glucose tolerance was consistent with functional MRI data in human volunteers that revealed an association of the DUSP8 rs2334499 risk variant with hypothalamic insulin resistance in men.	Glucose	113-120	dual specificity phosphatase 8	Mus musculus	32-37
23637839-6	2013	Results clearly link the effects of CBD and THC to inflammatory signaling pathways and identify new cannabinoid targets in the MAPK pathway (Dusp1, Dusp8, Dusp2), cell cycle related (Cdkn2b, Gadd45a) as well as JAK/STAT regulatory molecules (Socs3, Cish, Stat1).	Cannabinoids	100-111	dual specificity phosphatase 8	Mus musculus	148-153
23032483-11	2013	Thus, rosiglitazone"s neuroprotective effect after ischemia is mediated by blocking JNK phosphorylation induced by ischemia via DUSP8 upregulation.	Rosiglitazone	6-19	dual specificity phosphatase 8	Mus musculus	128-133
23032483-8	2013	Furthermore, we observed that rosiglitazone increased expression of the dual-specificity phosphatase 8 (DUSP8) protein and messenger RNA in ischemic brain tissue.	Rosiglitazone	30-43	dual specificity phosphatase 8	Mus musculus	72-102
23032483-8	2013	Furthermore, we observed that rosiglitazone increased expression of the dual-specificity phosphatase 8 (DUSP8) protein and messenger RNA in ischemic brain tissue.	Rosiglitazone	30-43	dual specificity phosphatase 8	Mus musculus	104-109
23032483-10	2013	Another key finding of the present study was that knockdown of DUSP8 in primary cultured cortical neurons that were subjected to oxygen-glucose deprivation diminished rosiglitazone"s effect on downregulation of JNK phosphorylation.	oxygen-glucose	129-143	dual specificity phosphatase 8	Mus musculus	63-68
23032483-10	2013	Another key finding of the present study was that knockdown of DUSP8 in primary cultured cortical neurons that were subjected to oxygen-glucose deprivation diminished rosiglitazone"s effect on downregulation of JNK phosphorylation.	Rosiglitazone	167-180	dual specificity phosphatase 8	Mus musculus	63-68