PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
33372486-9	2021	The NRK combining natural and human factors significantly improved the simulation accuracy of the spatial distribution of soil cadmium, and the addition of human factors as auxiliary variables, especially atmospheric point source pollution emissions, greatly contributed to the improvement of the model accuracy.	Cadmium	127-134	Nik related kinase	Homo sapiens	4-7
17914902-1	2007	The eukaryotic nicotinamide riboside kinase (Nrk) pathway, which is induced in response to nerve damage and promotes replicative life span in yeast, converts nicotinamide riboside to nicotinamide adenine dinucleotide (NAD+) by phosphorylation and adenylylation.	nicotinamide-beta-riboside	15-36	Nik related kinase	Homo sapiens	45-48
17914902-1	2007	The eukaryotic nicotinamide riboside kinase (Nrk) pathway, which is induced in response to nerve damage and promotes replicative life span in yeast, converts nicotinamide riboside to nicotinamide adenine dinucleotide (NAD+) by phosphorylation and adenylylation.	NAD	183-216	Nik related kinase	Homo sapiens	45-48
17914902-1	2007	The eukaryotic nicotinamide riboside kinase (Nrk) pathway, which is induced in response to nerve damage and promotes replicative life span in yeast, converts nicotinamide riboside to nicotinamide adenine dinucleotide (NAD+) by phosphorylation and adenylylation.	NAD	218-222	Nik related kinase	Homo sapiens	45-48
17914902-4	2007	Indeed, nicotinic acid riboside is a specific substrate of human Nrk enzymes and is utilized in yeast in a novel biosynthetic pathway that depends on Nrk and NAD+ synthetase.	nicotinic acid riboside	8-31	Nik related kinase	Homo sapiens	150-153
17914902-4	2007	Indeed, nicotinic acid riboside is a specific substrate of human Nrk enzymes and is utilized in yeast in a novel biosynthetic pathway that depends on Nrk and NAD+ synthetase.	nicotinic acid riboside	8-31	Nik related kinase	Homo sapiens	65-68
12837278-7	2003	Since the phosphorylation at Ser-3 inactivates the actin-depolymerizing activity of cofilin, these results suggest that NRK/NESK induces actin polymerization through cofilin phosphorylation.	Serine	29-32	Nik related kinase	Homo sapiens	120-123
15913957-5	2005	Treatment of NESK-transfected HeLa cells with TNF-alpha in the presence of cycloheximide or with staurosporine induced proteolytic cleavage of NESK.	Cycloheximide	75-88	Nik related kinase	Homo sapiens	13-17
15913957-5	2005	Treatment of NESK-transfected HeLa cells with TNF-alpha in the presence of cycloheximide or with staurosporine induced proteolytic cleavage of NESK.	Cycloheximide	75-88	Nik related kinase	Homo sapiens	143-147
15913957-5	2005	Treatment of NESK-transfected HeLa cells with TNF-alpha in the presence of cycloheximide or with staurosporine induced proteolytic cleavage of NESK.	Staurosporine	97-110	Nik related kinase	Homo sapiens	13-17
15913957-5	2005	Treatment of NESK-transfected HeLa cells with TNF-alpha in the presence of cycloheximide or with staurosporine induced proteolytic cleavage of NESK.	Staurosporine	97-110	Nik related kinase	Homo sapiens	143-147
12837278-7	2003	Since the phosphorylation at Ser-3 inactivates the actin-depolymerizing activity of cofilin, these results suggest that NRK/NESK induces actin polymerization through cofilin phosphorylation.	Serine	29-32	Nik related kinase	Homo sapiens	124-128
8824562-5	1996	Herbimycin A and radicicol, which have been reported to block Src function, suppressed the growth of v-src-transformed NRK and HAG-1 cells on the non-adhesive polyHEMA-surface at concentrations significantly lower than on plastic.	herbimycin	0-12	Nik related kinase	Homo sapiens	119-122
10866047-5	2000	However, these cells, designated NESK beta-cells, have impaired insulin gene transcription responses to glucose.	Glucose	104-111	Nik related kinase	Homo sapiens	33-37
8824562-5	1996	Herbimycin A and radicicol, which have been reported to block Src function, suppressed the growth of v-src-transformed NRK and HAG-1 cells on the non-adhesive polyHEMA-surface at concentrations significantly lower than on plastic.	monorden	17-26	Nik related kinase	Homo sapiens	119-122
35432899-8	2022	Localizing the same NRK dye in different organelles by the hydrazide ligands is found to affect drastically its photodynamic activity, with the most pronounced phototoxic effects in mitochondria and plasma membranes.	hydrazide	59-68	Nik related kinase	Homo sapiens	20-23
35432899-5	2022	We show that dynamic hydrazone bond can be formed between these hydrazide ligands and a ketone-functionalized Nile Red dye (NRK) in situ in model lipid membranes or nanoemulsion droplets.	Hydrazones	21-30	Nik related kinase	Homo sapiens	124-127
35432899-5	2022	We show that dynamic hydrazone bond can be formed between these hydrazide ligands and a ketone-functionalized Nile Red dye (NRK) in situ in model lipid membranes or nanoemulsion droplets.	hydrazide	64-73	Nik related kinase	Homo sapiens	124-127
35432899-5	2022	We show that dynamic hydrazone bond can be formed between these hydrazide ligands and a ketone-functionalized Nile Red dye (NRK) in situ in model lipid membranes or nanoemulsion droplets.	Ketones	88-94	Nik related kinase	Homo sapiens	124-127
35432899-5	2022	We show that dynamic hydrazone bond can be formed between these hydrazide ligands and a ketone-functionalized Nile Red dye (NRK) in situ in model lipid membranes or nanoemulsion droplets.	nile red dye	110-122	Nik related kinase	Homo sapiens	124-127
35432899-6	2022	Fluorescence imaging in live cells reveals that the targeting hydrazide ligands can induce preferential localization of NRK dye and an anti-cancer drug doxorubicin in plasma membranes, mitochondria and lipid droplets.	hydrazide	62-71	Nik related kinase	Homo sapiens	120-123