PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
7901008-1	1993	Phosphoglucose isomerase pgi1-deletion mutants of Saccharomyces cerevisiae cannot grow on glucose as the sole carbon source and are even inhibited by glucose.	Glucose	7-14	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	25-29
19711072-1	2010	Phosphoglucose isomerase-deficient (pgi1) strains of Saccharomyces cerevisiae were studied for the production of D-ribose and ribitol from D-glucose via the intermediates of the pentose phosphate pathway.	Ribose	113-121	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	36-40
19711072-1	2010	Phosphoglucose isomerase-deficient (pgi1) strains of Saccharomyces cerevisiae were studied for the production of D-ribose and ribitol from D-glucose via the intermediates of the pentose phosphate pathway.	Ribitol	126-133	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	36-40
19711072-1	2010	Phosphoglucose isomerase-deficient (pgi1) strains of Saccharomyces cerevisiae were studied for the production of D-ribose and ribitol from D-glucose via the intermediates of the pentose phosphate pathway.	Glucose	139-148	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	36-40
19711072-1	2010	Phosphoglucose isomerase-deficient (pgi1) strains of Saccharomyces cerevisiae were studied for the production of D-ribose and ribitol from D-glucose via the intermediates of the pentose phosphate pathway.	Pentosephosphates	178-195	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	36-40
19711072-2	2010	Overexpression of the genes coding for NAD(+)-specific glutamate dehydrogenase (GDH2) of S. cerevisiae or NADPH-utilising glyceraldehyde-3-phosphate dehydrogenase (gapB) of Bacillus subtilis enabled growth of the pgi1 mutant strains on D-glucose.	NAD	39-45	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	213-217
19711072-2	2010	Overexpression of the genes coding for NAD(+)-specific glutamate dehydrogenase (GDH2) of S. cerevisiae or NADPH-utilising glyceraldehyde-3-phosphate dehydrogenase (gapB) of Bacillus subtilis enabled growth of the pgi1 mutant strains on D-glucose.	NADP	106-111	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	213-217
19394900-1	2009	This work describes a mediated amperometric method for simultaneous real-time probing of the NAD(P)H availability in two different phenotypes, fermentative and respiratory, of the phosphoglucose isomerase deletion mutant strain of S. cerevisiae, EBY44 [ENY.WA-1A pgi1-1D::URA3], and its parental strain, ENY.WA-1A.	nad(p)h	93-100	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	263-267
18036177-0	2008	Glucose utilization of strains lacking PGI1 and expressing a transhydrogenase suggests differences in the pentose phosphate capacity among Saccharomyces cerevisiae strains.	Glucose	0-7	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	39-43
18036177-0	2008	Glucose utilization of strains lacking PGI1 and expressing a transhydrogenase suggests differences in the pentose phosphate capacity among Saccharomyces cerevisiae strains.	Pentosephosphates	106-123	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	39-43
18036177-1	2008	Saccharomyces cerevisiae strains lacking phosphoglucose isomerase (pgi1) cannot use the pentose phosphate (PP) pathway to oxidize glucose, which has been explained by the lack of mechanism for reoxidation of the NADPH surplus.	Pentosephosphates	88-105	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	67-71
18036177-1	2008	Saccharomyces cerevisiae strains lacking phosphoglucose isomerase (pgi1) cannot use the pentose phosphate (PP) pathway to oxidize glucose, which has been explained by the lack of mechanism for reoxidation of the NADPH surplus.	NADP	212-217	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	67-71
12427047-1	2002	Deletion of the phosphoglucose isomerase gene, PGI1, in Saccharomyces cerevisiae leads to a phenotype for which glucose is toxic.	Glucose	23-30	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	47-51
12427047-7	2002	Presumably, operation of this enzyme in the reverse direction enabled the transformed S. cerevisiae pgi1 deletion mutant to reoxidize the excess NADPH produced when glucose catabolism was forced through the pentose pathway.	NADP	145-150	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	100-104
12427047-7	2002	Presumably, operation of this enzyme in the reverse direction enabled the transformed S. cerevisiae pgi1 deletion mutant to reoxidize the excess NADPH produced when glucose catabolism was forced through the pentose pathway.	Pentoses	207-214	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	100-104
12123456-4	2002	Mutations in the PGI1 and GND1 genes encoding carbon source utilization enzymes confer enhanced invasive growth that is unaffected by glucose but requires active Snf1.	Carbon	46-52	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	17-21
12123456-4	2002	Mutations in the PGI1 and GND1 genes encoding carbon source utilization enzymes confer enhanced invasive growth that is unaffected by glucose but requires active Snf1.	Glucose	134-141	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	17-21
12112236-2	2002	In S. cerevisiae, the pgi1 null mutation abolishes growth on glucose, whereas K.lactis rag2 null mutants still grow on glucose.	Glucose	61-68	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	22-26
10880465-3	2000	Partial loss-of-function alleles of PGI1, PMI40, PSA1, DPM1, ALG1, MNN10, SPT14, and OCH1, genes required for mannose utilization and protein glycosylation, activated a pheromone-response-pathway-dependent reporter (FUS1) in cells lacking a basal signal (ste4).	Mannose	110-117	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	36-40
10880465-4	2000	Pathway activation was suppressed by the addition of mannose to hexose isomerase mutants pgi1-101 and pmi40-101, which bypassed the requirement for mannose biosynthesis in these mutants.	Mannose	53-60	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	89-93
10880465-4	2000	Pathway activation was suppressed by the addition of mannose to hexose isomerase mutants pgi1-101 and pmi40-101, which bypassed the requirement for mannose biosynthesis in these mutants.	Mannose	148-155	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	89-93
10803891-4	2000	Strains deleted in the promoter of the phosphoglucose isomerase gene (PGI1) - resulting in reduced enzyme activities - increased the ethanol yield by 15%.	Ethanol	133-140	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	70-74
8202080-5	1994	We used oligonucleotide-directed mutagenesis of the PGI1 phosphoglucose isomerase gene to introduce pairs of closely spaced base substitutions that resulted in stop codons in one strand and only silent replacements in the other.	Oligonucleotides	8-23	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	52-56
8202080-6	1994	Introduction of the two stop codons into the PGI1 sense strand caused the same physiological defects as already observed for pgil deletion mutants.	pgil	125-129	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	45-49
7704269-1	1995	Saccharomyces cerevisiae mutants defective in the structural gene PGI1 lack phosphoglucose isomerase and hence cannot grow on glucose.	Glucose	83-90	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	66-70
7901008-1	1993	Phosphoglucose isomerase pgi1-deletion mutants of Saccharomyces cerevisiae cannot grow on glucose as the sole carbon source and are even inhibited by glucose.	Carbon	110-116	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	25-29
7901008-1	1993	Phosphoglucose isomerase pgi1-deletion mutants of Saccharomyces cerevisiae cannot grow on glucose as the sole carbon source and are even inhibited by glucose.	Glucose	90-97	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	25-29
7901008-4	1993	Suppression of the pgi1 deletion by over-expression of GDH2 was abolished in strains with a deletion of the glucose-6-phosphate dehydrogenase gene ZWF1 or gene GDH1 coding for the NADPH-dependent glutamate dehydrogenase.	NADP	180-185	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	19-23
7901008-6	1993	It is proposed that the growth defect of pgi1 deletion mutants on glucose is due to a rapid depletion of NADP which is needed as a cofactor in the oxidative reactions of the pentose phosphate pathway.	Glucose	66-73	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	41-45
7901008-6	1993	It is proposed that the growth defect of pgi1 deletion mutants on glucose is due to a rapid depletion of NADP which is needed as a cofactor in the oxidative reactions of the pentose phosphate pathway.	NADP	105-109	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	41-45
7901008-6	1993	It is proposed that the growth defect of pgi1 deletion mutants on glucose is due to a rapid depletion of NADP which is needed as a cofactor in the oxidative reactions of the pentose phosphate pathway.	Pentosephosphates	174-191	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	41-45
2792108-13	1989	The Km shows the same strong dependence on salt as the rabbit muscle enzyme, although somewhat less than the yeast glucose-6-phosphate isomerase.	Salts	43-47	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	115-144
8508783-4	1993	Fructose pulses administered to the pgi1 strain transiently decreased the glycolytic flux downstream of fructose-1,6-bisphosphate.	fructose-1,6-diphosphate	104-129	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	36-40
8508783-5	1993	Transcriptional induction of the PDC1 gene (encoding pyruvate decarboxylase) was observed after glucose or galactose pulses were applied to the pgi1 strain, demonstrating that metabolism of these sugars beyond glucose 6-phosphate is dispensable for PDC1 induction.	Glucose	96-103	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	144-148
8508783-5	1993	Transcriptional induction of the PDC1 gene (encoding pyruvate decarboxylase) was observed after glucose or galactose pulses were applied to the pgi1 strain, demonstrating that metabolism of these sugars beyond glucose 6-phosphate is dispensable for PDC1 induction.	Galactose	107-116	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	144-148
8508783-5	1993	Transcriptional induction of the PDC1 gene (encoding pyruvate decarboxylase) was observed after glucose or galactose pulses were applied to the pgi1 strain, demonstrating that metabolism of these sugars beyond glucose 6-phosphate is dispensable for PDC1 induction.	Sugars	196-202	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	144-148
8508783-10	1993	The absence of an increased glycolytic flux in the pgi1 mutant after administration of the sugar pulses while the concentrations of sugar and glycolytic intermediates were high, suggests that the initial signal for glucose repression could be linked to an increased glycolytic flux.	Sugars	91-96	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	51-55
8508783-10	1993	The absence of an increased glycolytic flux in the pgi1 mutant after administration of the sugar pulses while the concentrations of sugar and glycolytic intermediates were high, suggests that the initial signal for glucose repression could be linked to an increased glycolytic flux.	Glucose	215-222	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	51-55
8508783-11	1993	The occurrence of PDC1 induction in the pgi1 strain while GAL10/HXKI repression is absent, demonstrates that the initial signals for catabolite induction and catabolite repression are different.	catabolite	133-143	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	40-44
8508783-11	1993	The occurrence of PDC1 induction in the pgi1 strain while GAL10/HXKI repression is absent, demonstrates that the initial signals for catabolite induction and catabolite repression are different.	catabolite	158-168	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	40-44
26271120-2	2015	We present here a finding that a gene, encoding the glycolysis enzyme phosphoglucose isomerase (Pgi1), is critical for the biosynthesis of melanin and capsule, cell wall integrity and resistance to stress conditions.	Melanins	139-146	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	96-100
26271120-8	2015	Furthermore, LZM19 failed to utilize mannose and fructose, suggesting a possible involvement of Pgi1 in the breakdown of these two sugars.	Sugars	131-137	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	96-100
8508783-1	1993	Wild-type Saccharomyces cerevisiae and a strain carrying a deletion in the glucose-6-phosphate-isomerase gene (pgi1) were grown in carbon-limited continuous cultures on a mixture of fructose and galactose.	Carbon	131-137	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	75-104
8508783-1	1993	Wild-type Saccharomyces cerevisiae and a strain carrying a deletion in the glucose-6-phosphate-isomerase gene (pgi1) were grown in carbon-limited continuous cultures on a mixture of fructose and galactose.	Carbon	131-137	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	111-115
8508783-1	1993	Wild-type Saccharomyces cerevisiae and a strain carrying a deletion in the glucose-6-phosphate-isomerase gene (pgi1) were grown in carbon-limited continuous cultures on a mixture of fructose and galactose.	Fructose	182-190	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	111-115
8508783-1	1993	Wild-type Saccharomyces cerevisiae and a strain carrying a deletion in the glucose-6-phosphate-isomerase gene (pgi1) were grown in carbon-limited continuous cultures on a mixture of fructose and galactose.	Galactose	195-204	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	111-115
8508783-3	1993	Glucose and galactose pulses inhibited fructose consumption and thus glycolysis in the pgi1 strain by a combination of competition between glucose and fructose at the uptake and/or phosphorylation level and inhibition of fructose uptake and/or phosphorylation by glucose 6-phosphate.	Fructose	39-47	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	87-91
8508783-3	1993	Glucose and galactose pulses inhibited fructose consumption and thus glycolysis in the pgi1 strain by a combination of competition between glucose and fructose at the uptake and/or phosphorylation level and inhibition of fructose uptake and/or phosphorylation by glucose 6-phosphate.	Glucose	139-146	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	87-91
8508783-3	1993	Glucose and galactose pulses inhibited fructose consumption and thus glycolysis in the pgi1 strain by a combination of competition between glucose and fructose at the uptake and/or phosphorylation level and inhibition of fructose uptake and/or phosphorylation by glucose 6-phosphate.	Fructose	151-159	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	87-91
8508783-3	1993	Glucose and galactose pulses inhibited fructose consumption and thus glycolysis in the pgi1 strain by a combination of competition between glucose and fructose at the uptake and/or phosphorylation level and inhibition of fructose uptake and/or phosphorylation by glucose 6-phosphate.	Fructose	151-159	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	87-91
8508783-3	1993	Glucose and galactose pulses inhibited fructose consumption and thus glycolysis in the pgi1 strain by a combination of competition between glucose and fructose at the uptake and/or phosphorylation level and inhibition of fructose uptake and/or phosphorylation by glucose 6-phosphate.	Glucose-6-Phosphate	263-282	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	87-91
8508783-4	1993	Fructose pulses administered to the pgi1 strain transiently decreased the glycolytic flux downstream of fructose-1,6-bisphosphate.	Fructose	0-8	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	36-40
1856676-5	1991	After a temperature shift-up a cdc30-bearing strain had cell cycle arrested and contained only 8% of the polysaccharide in the wild-type.	Polysaccharides	105-119	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	31-36
1856676-7	1991	Since the cdc30 mutation confers a temperature-sensitive phosphoglucose isomerase, the likely explanation for cell cycle arrest caused by this mutation is that the defective phosphoglucose isomerase results in a reduction of F6-P and hence an inability to synthesize the mannan and chitin needed for cytokinesis and cell separation.	Mannans	271-277	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	10-15
1856676-7	1991	Since the cdc30 mutation confers a temperature-sensitive phosphoglucose isomerase, the likely explanation for cell cycle arrest caused by this mutation is that the defective phosphoglucose isomerase results in a reduction of F6-P and hence an inability to synthesize the mannan and chitin needed for cytokinesis and cell separation.	Chitin	282-288	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	10-15
1856676-8	1991	Revertants of a pgi1-1 bearing strain were selected for their ability to grow on glucose at 25 degrees C and this yielded a number of different phenotypes.	Glucose	81-88	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	16-20
2792108-15	1989	Agaricic acid, a potent inhibitor of various glycosomal enzymes of T. brucei, has also a strong, irreversible effect on glucose-6-phosphate isomerase, while leaving the yeast and mammalian enzymes relatively unaffected.	agaric acid	0-13	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	120-149
2691359-0	1989	Inhibition of hexose transport by glucose in a glucose-6-phosphate isomerase mutant of Saccharomyces cerevisiae.	Hexoses	14-20	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	47-76
2691359-0	1989	Inhibition of hexose transport by glucose in a glucose-6-phosphate isomerase mutant of Saccharomyces cerevisiae.	Glucose	34-41	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	47-76
2691359-1	1989	The rate of hexose transport was approximately 60% lower for both the high- and the low-affinity components of hexose uptake when a glucose-6-phosphate isomerase mutant of Saccharomyces cerevisiae was preincubated with glucose, as compared with preincubation with water.	Hexoses	12-18	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	132-161
2691359-1	1989	The rate of hexose transport was approximately 60% lower for both the high- and the low-affinity components of hexose uptake when a glucose-6-phosphate isomerase mutant of Saccharomyces cerevisiae was preincubated with glucose, as compared with preincubation with water.	Hexoses	111-117	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	132-161
2691359-1	1989	The rate of hexose transport was approximately 60% lower for both the high- and the low-affinity components of hexose uptake when a glucose-6-phosphate isomerase mutant of Saccharomyces cerevisiae was preincubated with glucose, as compared with preincubation with water.	Water	264-269	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	132-161
3352745-5	1988	In our work on the molecular genetics of carbohydrate metabolism we have recently isolated a mouse glucose-6-phosphate isomerase (or phosphoglucose isomerase, PGI) cDNA clone using the yeast PGI gene (PGI 1) as a probe.	Carbohydrates	41-53	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	201-206
3352745-5	1988	In our work on the molecular genetics of carbohydrate metabolism we have recently isolated a mouse glucose-6-phosphate isomerase (or phosphoglucose isomerase, PGI) cDNA clone using the yeast PGI gene (PGI 1) as a probe.	Prostaglandins I	159-162	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	201-206
3352745-5	1988	In our work on the molecular genetics of carbohydrate metabolism we have recently isolated a mouse glucose-6-phosphate isomerase (or phosphoglucose isomerase, PGI) cDNA clone using the yeast PGI gene (PGI 1) as a probe.	Prostaglandins I	191-194	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	201-206
3329972-1	1987	A mutant with a deletion covering the phosphoglucose isomerase gene PGI1, allele pgil delta, can only grow on a medium containing fructose and low concentrations of glucose whereas growth is completely inhibited by glucose concentrations higher than 0.4%.	Fructose	130-138	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	68-72
3329972-1	1987	A mutant with a deletion covering the phosphoglucose isomerase gene PGI1, allele pgil delta, can only grow on a medium containing fructose and low concentrations of glucose whereas growth is completely inhibited by glucose concentrations higher than 0.4%.	Glucose	45-52	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	68-72
3329972-1	1987	A mutant with a deletion covering the phosphoglucose isomerase gene PGI1, allele pgil delta, can only grow on a medium containing fructose and low concentrations of glucose whereas growth is completely inhibited by glucose concentrations higher than 0.4%.	Glucose	165-172	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	68-72
32893576-2	2020	The promoter of phosphoglucose isomerase gene(PGI1) was replaced by that of cytochrome c oxidase subunit VIIa(Cox9)to weaken its expression, aiming to channel more carbon flux into the NADPH-producing pathway.	Carbon	164-170	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	46-50
32893576-2	2020	The promoter of phosphoglucose isomerase gene(PGI1) was replaced by that of cytochrome c oxidase subunit VIIa(Cox9)to weaken its expression, aiming to channel more carbon flux into the NADPH-producing pathway.	NADP	185-190	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	46-50
32893576-6	2020	This study successfully knocked out the CITT2 and MLS1 genes and weakened the PGI1 gene by using CRISPR/CAS9, which directly influenced the production of beta-amyrin and provided some reference for the the metabolic engineering of triterpernoid producing strain.	beta-amyrin	154-165	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	78-82
32893576-6	2020	This study successfully knocked out the CITT2 and MLS1 genes and weakened the PGI1 gene by using CRISPR/CAS9, which directly influenced the production of beta-amyrin and provided some reference for the the metabolic engineering of triterpernoid producing strain.	triterpernoid	231-244	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	78-82
3076183-1	1988	Spontaneous revertants of the cdc30 mutation in Saccharomyces cerevisiae simultaneously regained the ability to grow and divide at 36.5 degrees C on glucose-containing media along with a more thermostable phosphoglucose isomerase (PGI).	Glucose	149-156	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	30-35
3076183-5	1988	Diploid strains homozygous for the cdc30 mutation sporulated poorly in potassium acetate irrespective of whether the cells had previously been cultured at a temperature that was permissive or restrictive for cell cycle progression.	Potassium Acetate	71-88	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	35-40
3309140-1	1987	The cdc30 mutation in the yeast Saccharomyces cerevisiae causes cell cycle arrest late in nuclear division when cells are shifted from the permissive temperature of 25 degrees C to the restrictive temperature of 36.5 degrees C. Cell cycle arrest at 36.5 degrees C is dependent upon the carbon source used: a shift-up in glucose containing media results in cell cycle blockade, whereas a shift-up in ethanol, fructose, glycerol, glycerol plus ethanol, or mannose does not.	Carbon	286-292	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	4-9
3309140-1	1987	The cdc30 mutation in the yeast Saccharomyces cerevisiae causes cell cycle arrest late in nuclear division when cells are shifted from the permissive temperature of 25 degrees C to the restrictive temperature of 36.5 degrees C. Cell cycle arrest at 36.5 degrees C is dependent upon the carbon source used: a shift-up in glucose containing media results in cell cycle blockade, whereas a shift-up in ethanol, fructose, glycerol, glycerol plus ethanol, or mannose does not.	Glucose	320-327	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	4-9
3309140-1	1987	The cdc30 mutation in the yeast Saccharomyces cerevisiae causes cell cycle arrest late in nuclear division when cells are shifted from the permissive temperature of 25 degrees C to the restrictive temperature of 36.5 degrees C. Cell cycle arrest at 36.5 degrees C is dependent upon the carbon source used: a shift-up in glucose containing media results in cell cycle blockade, whereas a shift-up in ethanol, fructose, glycerol, glycerol plus ethanol, or mannose does not.	Ethanol	399-406	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	4-9
3309140-1	1987	The cdc30 mutation in the yeast Saccharomyces cerevisiae causes cell cycle arrest late in nuclear division when cells are shifted from the permissive temperature of 25 degrees C to the restrictive temperature of 36.5 degrees C. Cell cycle arrest at 36.5 degrees C is dependent upon the carbon source used: a shift-up in glucose containing media results in cell cycle blockade, whereas a shift-up in ethanol, fructose, glycerol, glycerol plus ethanol, or mannose does not.	Fructose	408-416	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	4-9
3309140-1	1987	The cdc30 mutation in the yeast Saccharomyces cerevisiae causes cell cycle arrest late in nuclear division when cells are shifted from the permissive temperature of 25 degrees C to the restrictive temperature of 36.5 degrees C. Cell cycle arrest at 36.5 degrees C is dependent upon the carbon source used: a shift-up in glucose containing media results in cell cycle blockade, whereas a shift-up in ethanol, fructose, glycerol, glycerol plus ethanol, or mannose does not.	Glycerol	418-426	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	4-9
3309140-1	1987	The cdc30 mutation in the yeast Saccharomyces cerevisiae causes cell cycle arrest late in nuclear division when cells are shifted from the permissive temperature of 25 degrees C to the restrictive temperature of 36.5 degrees C. Cell cycle arrest at 36.5 degrees C is dependent upon the carbon source used: a shift-up in glucose containing media results in cell cycle blockade, whereas a shift-up in ethanol, fructose, glycerol, glycerol plus ethanol, or mannose does not.	Glycerol	428-436	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	4-9
3309140-1	1987	The cdc30 mutation in the yeast Saccharomyces cerevisiae causes cell cycle arrest late in nuclear division when cells are shifted from the permissive temperature of 25 degrees C to the restrictive temperature of 36.5 degrees C. Cell cycle arrest at 36.5 degrees C is dependent upon the carbon source used: a shift-up in glucose containing media results in cell cycle blockade, whereas a shift-up in ethanol, fructose, glycerol, glycerol plus ethanol, or mannose does not.	Ethanol	442-449	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	4-9
3309140-1	1987	The cdc30 mutation in the yeast Saccharomyces cerevisiae causes cell cycle arrest late in nuclear division when cells are shifted from the permissive temperature of 25 degrees C to the restrictive temperature of 36.5 degrees C. Cell cycle arrest at 36.5 degrees C is dependent upon the carbon source used: a shift-up in glucose containing media results in cell cycle blockade, whereas a shift-up in ethanol, fructose, glycerol, glycerol plus ethanol, or mannose does not.	Mannose	454-461	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	4-9
3309140-2	1987	Metabolite analyses showed accumulation of glucose 6-phosphate in a cdc30-bearing strain after a temperature shift-up in glucose-containing medium.	Glucose-6-Phosphate	43-62	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	68-73
3309140-2	1987	Metabolite analyses showed accumulation of glucose 6-phosphate in a cdc30-bearing strain after a temperature shift-up in glucose-containing medium.	Glucose	43-50	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	68-73
3309140-4	1987	We propose that the gene products of both the CDC30 and PG11 genes are required for cell cycle progression in glucose media and that the PGI1 gene product has a regulatory function over the CDC30 gene product.	Glucose	110-117	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	46-51
3020369-8	1986	Furthermore, pgi1 mutants with residual enzymatic activity grew very slowly on fructose-supplemented media containing up to 2% glucose.	Fructose	79-87	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	13-17
3020369-8	1986	Furthermore, pgi1 mutants with residual enzymatic activity grew very slowly on fructose-supplemented media containing up to 2% glucose.	Glucose	127-134	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	13-17
3020369-10	1986	Also the pgi1 delta strains did not grow in glucose as sole carbon source.	Carbon	60-66	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	9-13
132439-8	1976	The utilization of fructose 6-sulfate as a substrate by yeast glucose-6-phosphate isomerase could not be demonstrated.	fructose 6-sulfate	19-37	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	62-91
29771304-3	2018	To force simultaneous utilisation of xylose and glucose, the genes encoding glucose-6-phosphate isomerase (PGI1) and ribulose-5-phosphate epimerase (RPE1) were deleted in a xylose-isomerase-based xylose-fermenting strain with a modified oxidative pentose-phosphate pathway.	Xylose	37-43	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	76-105
29771304-3	2018	To force simultaneous utilisation of xylose and glucose, the genes encoding glucose-6-phosphate isomerase (PGI1) and ribulose-5-phosphate epimerase (RPE1) were deleted in a xylose-isomerase-based xylose-fermenting strain with a modified oxidative pentose-phosphate pathway.	Xylose	37-43	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	107-111
29771304-3	2018	To force simultaneous utilisation of xylose and glucose, the genes encoding glucose-6-phosphate isomerase (PGI1) and ribulose-5-phosphate epimerase (RPE1) were deleted in a xylose-isomerase-based xylose-fermenting strain with a modified oxidative pentose-phosphate pathway.	Glucose	48-55	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	76-105
29771304-3	2018	To force simultaneous utilisation of xylose and glucose, the genes encoding glucose-6-phosphate isomerase (PGI1) and ribulose-5-phosphate epimerase (RPE1) were deleted in a xylose-isomerase-based xylose-fermenting strain with a modified oxidative pentose-phosphate pathway.	Pentoses	247-254	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	76-105
29771304-3	2018	To force simultaneous utilisation of xylose and glucose, the genes encoding glucose-6-phosphate isomerase (PGI1) and ribulose-5-phosphate epimerase (RPE1) were deleted in a xylose-isomerase-based xylose-fermenting strain with a modified oxidative pentose-phosphate pathway.	Pentoses	247-254	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	107-111
29771304-3	2018	To force simultaneous utilisation of xylose and glucose, the genes encoding glucose-6-phosphate isomerase (PGI1) and ribulose-5-phosphate epimerase (RPE1) were deleted in a xylose-isomerase-based xylose-fermenting strain with a modified oxidative pentose-phosphate pathway.	Phosphates	86-95	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	107-111
20806246-3	2010	Using this strain it was revealed that Stb5p acts as a repressor for PGI1 encoding glucose-6-phosphate isomerase under acetaldehyde stress.	pgi1	69-73	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	83-112
20806246-3	2010	Using this strain it was revealed that Stb5p acts as a repressor for PGI1 encoding glucose-6-phosphate isomerase under acetaldehyde stress.	Acetaldehyde	119-131	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	83-112