PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 8728408-1 1996 In order to identify dipole generators of the N20/P20 and P25, we employed second-order-differentiation in the temporal dimension (temporal-second-order-differentiation; TSOD) with delta t = 2 msec. dipole 21-27 tubulin polymerization promoting protein family member 3 Homo sapiens 46-61 8662843-5 1996 Following a cleavage of p45 at a site that becomes the COOH terminus of p20, a more active intermediate is formed which migrates on SDS-polyacrylamide gel electrophoresis with an molecular mass of 35 kDa (ED50 of approximately 0.1 microM L-742,395 labeling versus 5 microM for p45). Sodium Dodecyl Sulfate 132-135 tubulin polymerization promoting protein family member 3 Homo sapiens 72-75 8662843-5 1996 Following a cleavage of p45 at a site that becomes the COOH terminus of p20, a more active intermediate is formed which migrates on SDS-polyacrylamide gel electrophoresis with an molecular mass of 35 kDa (ED50 of approximately 0.1 microM L-742,395 labeling versus 5 microM for p45). polyacrylamide 136-150 tubulin polymerization promoting protein family member 3 Homo sapiens 72-75 8662843-9 1996 Less than 50% of the p45 is cleaved down to active p20 or p22 ICE as determined by band shift on SDS-polyacrylamide gel electrophoresis of the biotinylated fragments, indicating that the in vitro activation is highly inefficient. Sodium Dodecyl Sulfate 97-100 tubulin polymerization promoting protein family member 3 Homo sapiens 51-54 8662843-9 1996 Less than 50% of the p45 is cleaved down to active p20 or p22 ICE as determined by band shift on SDS-polyacrylamide gel electrophoresis of the biotinylated fragments, indicating that the in vitro activation is highly inefficient. polyacrylamide 101-115 tubulin polymerization promoting protein family member 3 Homo sapiens 51-54 8662843-11 1996 Cleavage of p45 by exogenous p20/p10 ICE differs from that of the endogenous p45 cleavage activity in that the p20/p10 activity is more salt sensitive, and it produces a different pattern of cleavage fragments, principally 35- and 12-kDa fragments. Salts 136-140 tubulin polymerization promoting protein family member 3 Homo sapiens 29-32 8662843-11 1996 Cleavage of p45 by exogenous p20/p10 ICE differs from that of the endogenous p45 cleavage activity in that the p20/p10 activity is more salt sensitive, and it produces a different pattern of cleavage fragments, principally 35- and 12-kDa fragments. Salts 136-140 tubulin polymerization promoting protein family member 3 Homo sapiens 111-114 7766829-14 1995 P20, with 8 Aib residues, also shows looser packing of alpha-helices. 2-aminoisobutyric acid 12-15 tubulin polymerization promoting protein family member 3 Homo sapiens 0-3 8561965-1 1995 14.3.3 protein, a brain-specific protein, is an activator of tyrosine and tryptophan hydroxylases, key enzymes for biosynthesis of dopamine and serotonin. Dopamine 131-139 tubulin polymerization promoting protein family member 3 Homo sapiens 18-40 8561965-1 1995 14.3.3 protein, a brain-specific protein, is an activator of tyrosine and tryptophan hydroxylases, key enzymes for biosynthesis of dopamine and serotonin. Serotonin 144-153 tubulin polymerization promoting protein family member 3 Homo sapiens 18-40 8195168-2 1994 p20 co-eluted with alpha B crystallin and HSP27/28 during column chromatography on DEAE-Sepharose and on Bio-Gel A-5m. deae-sepharose 83-97 tubulin polymerization promoting protein family member 3 Homo sapiens 0-3 8044845-2 1994 The crystal structure at 2.5 A resolution of a recombinant human ICE-tetrapeptide chloromethylketone complex reveals that the holoenzyme is a homodimer of catalytic domains, each of which contains a p20 and a p10 subunit. chloromethylketone 82-100 tubulin polymerization promoting protein family member 3 Homo sapiens 199-202 8195168-3 1994 p20 was separated from alpha B crystallin and HSP27/28 and was resolved into two fractions, a minor first peak and a major second peak, by column chromatography on S-Sepharose in the presence of 7 M urea. Sepharose 166-175 tubulin polymerization promoting protein family member 3 Homo sapiens 0-3 8195168-3 1994 p20 was separated from alpha B crystallin and HSP27/28 and was resolved into two fractions, a minor first peak and a major second peak, by column chromatography on S-Sepharose in the presence of 7 M urea. Urea 199-203 tubulin polymerization promoting protein family member 3 Homo sapiens 0-3 8091393-6 1994 Heparin and sera from patients with HAT stimulated GT platelets in the same manner as determined by 14C-serotonin release and the changes in phosphorylation of p20 and p47. Heparin 0-7 tubulin polymerization promoting protein family member 3 Homo sapiens 160-163 7976012-3 1994 The amplitudes of the three major peaks (P20, N50, and P90) of the cortical somatosensory EP were significantly reduced following interruption of the contralateral DC. Deoxycytidine 164-166 tubulin polymerization promoting protein family member 3 Homo sapiens 41-44 1899476-0 1991 Regulation of binding of rhoB p20 to membranes by its specific regulatory protein, GDP dissociation inhibitor. Guanosine Diphosphate 83-86 tubulin polymerization promoting protein family member 3 Homo sapiens 30-33 8220907-18 1993 Beta-gamma-Methylene ATP, a selective P20 agonist, was approximately 100 times more potent than ATP as a vasoconstrictor, but only caused transient increases in perfusion pressure.6. beta-gamma-methylene atp 0-24 tubulin polymerization promoting protein family member 3 Homo sapiens 38-41 8220907-18 1993 Beta-gamma-Methylene ATP, a selective P20 agonist, was approximately 100 times more potent than ATP as a vasoconstrictor, but only caused transient increases in perfusion pressure.6. Adenosine Triphosphate 21-24 tubulin polymerization promoting protein family member 3 Homo sapiens 38-41 8446594-7 1993 Expression in Escherichia coli of a truncated cDNA encoding Asn119-His402 generated active enzyme, which was autocatalytically processed at three internal Asp-Xaa bonds to generate a p20 subunit (Asn119-Asp296) complexed with either p11 (Ala309-His402) or p10. xanthenone-4-acetic acid 159-162 tubulin polymerization promoting protein family member 3 Homo sapiens 183-186 1382425-5 1992 Tyrphostins inhibited the thrombin-elicited early phosphorylation of p43 and p20, substrates for protein kinase C (PKC) and myosin light chain kinase, respectively, at short times of activation. Tyrphostins 0-11 tubulin polymerization promoting protein family member 3 Homo sapiens 77-80 1382425-9 1992 The ability of tyrphostins to inhibit phosphorylation of p43 and p20 when induced by thrombin but not when induced by PMA confirms that PTKs may be involved subsequent to PKC activation. Tyrphostins 15-26 tubulin polymerization promoting protein family member 3 Homo sapiens 65-68 1899476-4 1991 Both the GDP- and GTP-bound forms of rhoB p20 bound to the membranes. Guanosine Diphosphate 9-12 tubulin polymerization promoting protein family member 3 Homo sapiens 42-45 1899476-4 1991 Both the GDP- and GTP-bound forms of rhoB p20 bound to the membranes. Guanosine Triphosphate 18-21 tubulin polymerization promoting protein family member 3 Homo sapiens 42-45 1899476-6 1991 rho GDI inhibited the binding of the GDP-bound form of rhoB p20, but not that of the GTP-bound form, to the membranes. Guanosine Diphosphate 37-40 tubulin polymerization promoting protein family member 3 Homo sapiens 60-63 1899476-7 1991 Moreover, rho GDI induced the dissociation of the GDP-bound form, but not that of the GTP-bound form, of rhoB p20 exogenously bound to the membranes from them. Guanosine Diphosphate 50-53 tubulin polymerization promoting protein family member 3 Homo sapiens 110-113 2174010-7 1990 On the contrary, P20 and P47 phosphorylation induced by 50 nM of 12-O-tetradecanoylphorbol-13-acetate, an activator of protein kinase C, was significantly decreased in the DM-A group. Tetradecanoylphorbol Acetate 65-101 tubulin polymerization promoting protein family member 3 Homo sapiens 17-20 34610423-2 2021 A novel series of compounds bearing a benzo(d)isoxazole scaffold was developed as PD-1/PD-L1 inhibitors, among them, compound P20 exhibited the most potent inhibitory activity, with an IC50 value of 26.8 nM. benzo(d)isoxazole 38-55 tubulin polymerization promoting protein family member 3 Homo sapiens 126-129 33798474-5 2021 When TrpRS was immobilized on Streptavidin (SA) sensor chip, the substrate competitive inhibitor indolmycin exhibited the best binding affinity in HBS-P (10 mM HEPES, 150 mM NaCl, 0.05% surfactant P-20, pH 7.4), 1 mM ATP and MgCl2, with a KD (dissociation equilibrium constant) value of 0.6 +- 0.1 muM. indolmycin 97-107 tubulin polymerization promoting protein family member 3 Homo sapiens 197-201 34710506-5 2021 IFN-gamma (100 ng/mL) plus poly (dA:dT) (2 mg/mL) induced the increased AURKA, secretion of IL-1beta, IL-18 and the active form of caspase-1 (p20). poly(dA) 27-36 tubulin polymerization promoting protein family member 3 Homo sapiens 142-145 34710506-5 2021 IFN-gamma (100 ng/mL) plus poly (dA:dT) (2 mg/mL) induced the increased AURKA, secretion of IL-1beta, IL-18 and the active form of caspase-1 (p20). Thymidine 36-39 tubulin polymerization promoting protein family member 3 Homo sapiens 142-145 34492927-5 2021 Besides, both 3-MA and CQ addition increased NLRP3, Caspase-1, NEK7, ASC, GSDMA, GSDME, IL-1beta, IL-18 mRNA levels, NLRP3, Caspase-1 p20, ASC, GSDMD protein and ROS levels, and NO, LDH, IL-1beta, IL-18 releases. 3-methyladenine 14-18 tubulin polymerization promoting protein family member 3 Homo sapiens 134-137 34598017-4 2021 3) Increased nuclear localization of pro-caspase-1 by a new NES peptide inhibitor upregulates inflammatory genes in oxidative stress and Th17 pathways; and SUMO activator N106 enhances nuclear localization of pro-caspase-1 and caspase-1 activation (p20) in the nucleus. N-(4-methoxybenzo[d]thiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine 171-175 tubulin polymerization promoting protein family member 3 Homo sapiens 249-252 34636999-6 2021 Finally, a discussion of the intramolecular force constants for cisplatin is carried out, with the calculated bond and angles force constants with P20 and P22 protocols being recommended for the parameterization of the force field of cisplatin. Cisplatin 234-243 tubulin polymerization promoting protein family member 3 Homo sapiens 147-150 34492927-5 2021 Besides, both 3-MA and CQ addition increased NLRP3, Caspase-1, NEK7, ASC, GSDMA, GSDME, IL-1beta, IL-18 mRNA levels, NLRP3, Caspase-1 p20, ASC, GSDMD protein and ROS levels, and NO, LDH, IL-1beta, IL-18 releases. Chloroquine 23-25 tubulin polymerization promoting protein family member 3 Homo sapiens 134-137 2538842-6 1989 However, the effect of analogs of cAMP on P9, P19, and P20 was not altered by inclusion of Co2+. Cyclic AMP 34-38 tubulin polymerization promoting protein family member 3 Homo sapiens 55-58 35145428-10 2021 SA as DA performed at P20 and P30 induces a bradycardia. sa 0-2 tubulin polymerization promoting protein family member 3 Homo sapiens 22-25 35145428-10 2021 SA as DA performed at P20 and P30 induces a bradycardia. da 6-8 tubulin polymerization promoting protein family member 3 Homo sapiens 22-25 2506853-0 1989 Kinetic analysis of the binding of guanine nucleotides to bovine brain rhoB p20, a ras p21-like GTP-binding protein. Guanine Nucleotides 35-54 tubulin polymerization promoting protein family member 3 Homo sapiens 76-79 2506853-0 1989 Kinetic analysis of the binding of guanine nucleotides to bovine brain rhoB p20, a ras p21-like GTP-binding protein. Guanosine Triphosphate 96-99 tubulin polymerization promoting protein family member 3 Homo sapiens 76-79 2506853-1 1989 We have investigated the kinetics of the binding of guanine nucleotides to bovine brain rhoB p20, a ras p21-like GTP-binding protein with GTPase activity. Guanine Nucleotides 52-71 tubulin polymerization promoting protein family member 3 Homo sapiens 93-96 2506853-1 1989 We have investigated the kinetics of the binding of guanine nucleotides to bovine brain rhoB p20, a ras p21-like GTP-binding protein with GTPase activity. Guanosine Triphosphate 113-116 tubulin polymerization promoting protein family member 3 Homo sapiens 93-96 2506853-2 1989 The initial velocities of the binding of guanosine 5"-(3-O-thio)triphosphate (GTP gamma S) to GDP-bound rhoB p20 and the dissociation of GDP from this protein were markedly increased by decreasing Mg2+ concentrations. Guanosine 5'-O-(3-Thiotriphosphate) 41-76 tubulin polymerization promoting protein family member 3 Homo sapiens 109-112 2506853-2 1989 The initial velocities of the binding of guanosine 5"-(3-O-thio)triphosphate (GTP gamma S) to GDP-bound rhoB p20 and the dissociation of GDP from this protein were markedly increased by decreasing Mg2+ concentrations. Guanosine Triphosphate 78-81 tubulin polymerization promoting protein family member 3 Homo sapiens 109-112 2420700-3 1986 P20 in the form of a single loop created by a disulphide based between residue 306 and an additional cysteine at position 330 was able to activate the helper T cells in the presence of accessory cells but unable to induce tolerance. disulphide 46-56 tubulin polymerization promoting protein family member 3 Homo sapiens 0-3 2538439-7 1989 PDGF also completely prevented phosphorylation of P43 and P20, as a result of protein kinase C activation consecutive to phosphoinositide metabolism. Phosphatidylinositols 121-137 tubulin polymerization promoting protein family member 3 Homo sapiens 58-61 3039999-2 1987 After a lag phase of 35 sec the mAb ALB6 induced a transient decrease in 32P-polyphosphoinositides, synthesis of 32P-phosphatidate (PA), phosphorylation of myosin light chain (P20) and of 43 KDa protein (P43) and the release reaction. alb6 36-40 tubulin polymerization promoting protein family member 3 Homo sapiens 176-179 2435534-2 1987 MN-SEPs in both frontal leads were characterized by an N18, P20, N24, P28 complex showing maximal amplitude at contralateral parasagittal sites. mn-seps 0-7 tubulin polymerization promoting protein family member 3 Homo sapiens 60-63 2427324-2 1986 It was found that when the contralateral parietal N20 negativity peaks there is a synchronous frontal P20 positivity, supporting the view of a tangentially orientated dipolar generator for this couple of scalp SEPs components. seps 210-214 tubulin polymerization promoting protein family member 3 Homo sapiens 102-105 2506853-2 1989 The initial velocities of the binding of guanosine 5"-(3-O-thio)triphosphate (GTP gamma S) to GDP-bound rhoB p20 and the dissociation of GDP from this protein were markedly increased by decreasing Mg2+ concentrations. Sulfur 88-89 tubulin polymerization promoting protein family member 3 Homo sapiens 109-112 2506853-2 1989 The initial velocities of the binding of guanosine 5"-(3-O-thio)triphosphate (GTP gamma S) to GDP-bound rhoB p20 and the dissociation of GDP from this protein were markedly increased by decreasing Mg2+ concentrations. Guanosine Diphosphate 94-97 tubulin polymerization promoting protein family member 3 Homo sapiens 109-112 2506853-2 1989 The initial velocities of the binding of guanosine 5"-(3-O-thio)triphosphate (GTP gamma S) to GDP-bound rhoB p20 and the dissociation of GDP from this protein were markedly increased by decreasing Mg2+ concentrations. magnesium ion 197-201 tubulin polymerization promoting protein family member 3 Homo sapiens 109-112 2506853-3 1989 The initial velocity of the binding of GTP gamma S to GDP-free rhoB p20 was not affected by changing Mg2+ concentrations. Guanosine Triphosphate 39-42 tubulin polymerization promoting protein family member 3 Homo sapiens 68-71 2506853-3 1989 The initial velocity of the binding of GTP gamma S to GDP-free rhoB p20 was not affected by changing Mg2+ concentrations. Guanosine Diphosphate 54-57 tubulin polymerization promoting protein family member 3 Homo sapiens 68-71 2506853-4 1989 These results indicate that the dissociation of GDP from rhoB p20 limits the binding of GTP to this protein, and suggest that there is a factor stimulating the dissociation of GDP from rhoB p20 and thereby stimulating the binding of GTP to this protein in mammalian tissues. Guanosine Diphosphate 48-51 tubulin polymerization promoting protein family member 3 Homo sapiens 62-65 2506853-4 1989 These results indicate that the dissociation of GDP from rhoB p20 limits the binding of GTP to this protein, and suggest that there is a factor stimulating the dissociation of GDP from rhoB p20 and thereby stimulating the binding of GTP to this protein in mammalian tissues. Guanosine Diphosphate 48-51 tubulin polymerization promoting protein family member 3 Homo sapiens 190-193 2506853-4 1989 These results indicate that the dissociation of GDP from rhoB p20 limits the binding of GTP to this protein, and suggest that there is a factor stimulating the dissociation of GDP from rhoB p20 and thereby stimulating the binding of GTP to this protein in mammalian tissues. Guanosine Triphosphate 88-91 tubulin polymerization promoting protein family member 3 Homo sapiens 62-65 2506853-4 1989 These results indicate that the dissociation of GDP from rhoB p20 limits the binding of GTP to this protein, and suggest that there is a factor stimulating the dissociation of GDP from rhoB p20 and thereby stimulating the binding of GTP to this protein in mammalian tissues. Guanosine Triphosphate 88-91 tubulin polymerization promoting protein family member 3 Homo sapiens 190-193 2506853-4 1989 These results indicate that the dissociation of GDP from rhoB p20 limits the binding of GTP to this protein, and suggest that there is a factor stimulating the dissociation of GDP from rhoB p20 and thereby stimulating the binding of GTP to this protein in mammalian tissues. Guanosine Diphosphate 176-179 tubulin polymerization promoting protein family member 3 Homo sapiens 62-65 2506853-4 1989 These results indicate that the dissociation of GDP from rhoB p20 limits the binding of GTP to this protein, and suggest that there is a factor stimulating the dissociation of GDP from rhoB p20 and thereby stimulating the binding of GTP to this protein in mammalian tissues. Guanosine Diphosphate 176-179 tubulin polymerization promoting protein family member 3 Homo sapiens 190-193 2506853-4 1989 These results indicate that the dissociation of GDP from rhoB p20 limits the binding of GTP to this protein, and suggest that there is a factor stimulating the dissociation of GDP from rhoB p20 and thereby stimulating the binding of GTP to this protein in mammalian tissues. Guanosine Triphosphate 233-236 tubulin polymerization promoting protein family member 3 Homo sapiens 62-65 2506853-4 1989 These results indicate that the dissociation of GDP from rhoB p20 limits the binding of GTP to this protein, and suggest that there is a factor stimulating the dissociation of GDP from rhoB p20 and thereby stimulating the binding of GTP to this protein in mammalian tissues. Guanosine Triphosphate 233-236 tubulin polymerization promoting protein family member 3 Homo sapiens 190-193 2506853-5 1989 Consistently, the factor stimulating the dissociation of GDP, but not of GTP gamma S, from rhoB p20 was detected in bovine brain cytosol. Guanosine Diphosphate 57-60 tubulin polymerization promoting protein family member 3 Homo sapiens 96-99 2454792-1 1988 The topography of early frontal SEPs (P20 and N26) to left median nerve stimulation was studied in 30 normal subjects and 3 patients with the left frontal bone defect. seps 32-36 tubulin polymerization promoting protein family member 3 Homo sapiens 38-41 2420700-3 1986 P20 in the form of a single loop created by a disulphide based between residue 306 and an additional cysteine at position 330 was able to activate the helper T cells in the presence of accessory cells but unable to induce tolerance. Cysteine 101-109 tubulin polymerization promoting protein family member 3 Homo sapiens 0-3 2420700-6 1986 Furthermore the retro-D-p20 isomer which has the same side chain topography as L-p20 but with a reversal of amino and carboxyl acid groups also failed to stimulate or tolerize. l 79-80 tubulin polymerization promoting protein family member 3 Homo sapiens 81-84 7002020-4 1980 In both sporadic and familial Alzheimer disease, sodium dodecylsulfate-polyacrylamide gel electrophoresis revealed marked augmentation of a 20,000 mw protein (P20) in neuronal fractions from affected cortex compared to Huntington disease patients and controls. Sodium Dodecyl Sulfate 49-71 tubulin polymerization promoting protein family member 3 Homo sapiens 159-162 3705017-3 1986 In the same condition, the degree of myosin light chain (P20) phosphorylation, however, was well correlated with ATP secretion and [Ca2+]i, when platelets were stimulated by lower dose of thrombin. Adenosine Triphosphate 113-116 tubulin polymerization promoting protein family member 3 Homo sapiens 57-60 6477519-6 1984 In permeabilized platelets, as in the intact cells, release of serotonin was associated with the Ca2+-dependent phosphorylation of 47 000 and 20 000 Da polypeptides (P47 and P20). Serotonin 63-72 tubulin polymerization promoting protein family member 3 Homo sapiens 174-177 6429882-4 1984 In the presence of ionophore, significant increases occurred in the phosphorylation of two polypeptides of 43,000 and 20,000 molecular weight ( P43 and P20) in a concentration dependent manner, and this was accompanied by an increase in the 14C-5HT release. 14c-5ht 241-248 tubulin polymerization promoting protein family member 3 Homo sapiens 152-155 6429882-5 1984 The 32P-labelling of P43 and P20 reaches a peak within 1 min of platelet activation and is followed by a rapid dephosphorylation over the next 2-10 min. Phosphorus-32 4-7 tubulin polymerization promoting protein family member 3 Homo sapiens 29-32 7002020-4 1980 In both sporadic and familial Alzheimer disease, sodium dodecylsulfate-polyacrylamide gel electrophoresis revealed marked augmentation of a 20,000 mw protein (P20) in neuronal fractions from affected cortex compared to Huntington disease patients and controls. polyacrylamide gels 71-89 tubulin polymerization promoting protein family member 3 Homo sapiens 159-162 216130-3 1978 Studies on the phosphorylation of proteins in intact 32P-labelled platelets showed that PGE1 increased the phosphorylation of a membrane-bound polypeptide (P24) and prevented the increased phosphorylation of other polypeptides (P47 and P20) that occurred on addition of inducers of the release reaction. Alprostadil 88-92 tubulin polymerization promoting protein family member 3 Homo sapiens 236-239 20221126-2 1980 The CO(2) lidar was used to measure the ratio of transmission of the P(38) to the P(20) lines in the 10-microm band of CO(2). co(2) 4-9 tubulin polymerization promoting protein family member 3 Homo sapiens 82-87 20221126-2 1980 The CO(2) lidar was used to measure the ratio of transmission of the P(38) to the P(20) lines in the 10-microm band of CO(2). co(2) 119-124 tubulin polymerization promoting protein family member 3 Homo sapiens 82-87 20212653-1 1979 A new analysis is presented for the atmospheric transmission of the CO(2)(P-20) line, which includes pressure shift, bleaching, and tuning off-line center. co(2) 68-73 tubulin polymerization promoting protein family member 3 Homo sapiens 74-78 375934-18 1979 of 47000 and 20000 (P47 and P20) caused by ionophore A23187, which may therefore short-circuit cyclic AMP-dependent mechanisms that decrease the Ca(2+) concentration in the platelet cytosol. Calcimycin 53-59 tubulin polymerization promoting protein family member 3 Homo sapiens 28-31 375934-18 1979 of 47000 and 20000 (P47 and P20) caused by ionophore A23187, which may therefore short-circuit cyclic AMP-dependent mechanisms that decrease the Ca(2+) concentration in the platelet cytosol. Cyclic AMP 95-105 tubulin polymerization promoting protein family member 3 Homo sapiens 28-31 216130-4 1978 It is suggested that the cyclic AMP-dependent phosphorylation of P24 stimulates the active transport of Ca(2+) out of the platelet cytosol, so preventing phosphorylation of P47 and P20, reactions which may be involved in the release mechanism. Cyclic AMP 25-35 tubulin polymerization promoting protein family member 3 Homo sapiens 181-184 20076365-0 1970 The Temperature Dependence of the Self-Broadened Half-Width of the P-20 Line in the 001-100 Band of CO(2). co(2) 100-105 tubulin polymerization promoting protein family member 3 Homo sapiens 67-71 710399-1 1978 The amino acid sequence of a brain-specific protein, S-100, has been determined by the analysis of four cyanogen bromide peptides and fourteen tryptic peptides derived from the protein. cyanogen bromide peptides 104-129 tubulin polymerization promoting protein family member 3 Homo sapiens 29-51 849537-1 1977 The duration of intraocular pressure reduction by Ocusert Pilocarpine was found to be 10 days for P20 and 12 days for P40. Pilocarpine 58-69 tubulin polymerization promoting protein family member 3 Homo sapiens 98-101 33433347-5 2021 Simultaneously, Mo or/and Cd upregulated ASC, NLRP3, NEK7, Caspase-1, GSDMA, GSDME, IL-18 and IL-1beta mRNA levels and Caspase-1 p20, NLRP3, ASC, GSDMD protein levels, increased the percentage of pyroptotic cells, LDH, NO, IL-18 and IL-1beta releases as well as relative conductivity. Cadmium 26-28 tubulin polymerization promoting protein family member 3 Homo sapiens 129-132 20068838-0 1968 Atmospheric absorption at the line center of P(20) CO(2) laser radiation. co(2) 51-56 tubulin polymerization promoting protein family member 3 Homo sapiens 45-50 20068838-1 1968 Atmospheric CO(2) absorption at the line center of P(20) CO(2) laser radiation has been calculated at different altitudes by using the relationship 1 - exp(-integral(l)(2)(l)(1) kdl). co(2) 12-17 tubulin polymerization promoting protein family member 3 Homo sapiens 51-56 20068838-1 1968 Atmospheric CO(2) absorption at the line center of P(20) CO(2) laser radiation has been calculated at different altitudes by using the relationship 1 - exp(-integral(l)(2)(l)(1) kdl). co(2) 57-62 tubulin polymerization promoting protein family member 3 Homo sapiens 51-56 33930507-4 2021 Full-length BAP31 can be anti-apoptotic, but can also mediate activation of caspase-8, and itself be cleaved by caspase-8 into p20-BAP31, which promotes apoptosis by mobilizing ER calcium stores at MAMs. Calcium 180-187 tubulin polymerization promoting protein family member 3 Homo sapiens 127-130 31915969-7 2020 The MAPE and P20 of Calvert-CKD-EPI-cysC were the lowest. ICE protocol 1 32-40 tubulin polymerization promoting protein family member 3 Homo sapiens 13-16 33898200-5 2021 When assessing the effect of flexoelectricity with a curvature of 1/20, the I pv of the curved KNN/PVDF-TrFE (20%) (K/P-20) composite increased by 13.9% compared to that of the flat K/P-20 nanocomposite. polyvinylidene fluoride 99-103 tubulin polymerization promoting protein family member 3 Homo sapiens 118-122 33898200-5 2021 When assessing the effect of flexoelectricity with a curvature of 1/20, the I pv of the curved KNN/PVDF-TrFE (20%) (K/P-20) composite increased by 13.9% compared to that of the flat K/P-20 nanocomposite. polyvinylidene fluoride 99-103 tubulin polymerization promoting protein family member 3 Homo sapiens 185-189 33898200-5 2021 When assessing the effect of flexoelectricity with a curvature of 1/20, the I pv of the curved KNN/PVDF-TrFE (20%) (K/P-20) composite increased by 13.9% compared to that of the flat K/P-20 nanocomposite. trfe 104-108 tubulin polymerization promoting protein family member 3 Homo sapiens 118-122 33898200-5 2021 When assessing the effect of flexoelectricity with a curvature of 1/20, the I pv of the curved KNN/PVDF-TrFE (20%) (K/P-20) composite increased by 13.9% compared to that of the flat K/P-20 nanocomposite. trfe 104-108 tubulin polymerization promoting protein family member 3 Homo sapiens 185-189 33497945-4 2020 Simultaneously, Cd also markedly upregulated NLRP3, Caspase-1, ASC, NEK7, IL-1beta and IL-18 mRNA levels and NLRP3, Caspase-1 p20, GSDMD and ASC protein levels. Cadmium 16-18 tubulin polymerization promoting protein family member 3 Homo sapiens 126-129 33082910-0 2020 Interaction of TPPP3 with VDAC1 Promotes Endothelial Injury through Activation of Reactive Oxygen Species. Oxygen 91-97 tubulin polymerization promoting protein family member 3 Homo sapiens 15-20 33082910-3 2020 The study is aimed at investigating the role of tubulin polymerization-promoting protein family member 3 (TPPP3) in palmitic acid- (PA-) induced endothelial injury. Palmitic Acid 116-129 tubulin polymerization promoting protein family member 3 Homo sapiens 48-104 33082910-3 2020 The study is aimed at investigating the role of tubulin polymerization-promoting protein family member 3 (TPPP3) in palmitic acid- (PA-) induced endothelial injury. Palmitic Acid 116-129 tubulin polymerization promoting protein family member 3 Homo sapiens 106-111 33082910-3 2020 The study is aimed at investigating the role of tubulin polymerization-promoting protein family member 3 (TPPP3) in palmitic acid- (PA-) induced endothelial injury. Protactinium 132-134 tubulin polymerization promoting protein family member 3 Homo sapiens 48-104 33082910-3 2020 The study is aimed at investigating the role of tubulin polymerization-promoting protein family member 3 (TPPP3) in palmitic acid- (PA-) induced endothelial injury. Protactinium 132-134 tubulin polymerization promoting protein family member 3 Homo sapiens 106-111 33082910-4 2020 The effect of TPPP3 on human umbilical vein endothelial cells (HUVECs) was determined by evaluating apoptosis, tube formation, and reactive oxygen species (ROS) production. Reactive Oxygen Species 131-154 tubulin polymerization promoting protein family member 3 Homo sapiens 14-19 33082910-4 2020 The effect of TPPP3 on human umbilical vein endothelial cells (HUVECs) was determined by evaluating apoptosis, tube formation, and reactive oxygen species (ROS) production. Reactive Oxygen Species 156-159 tubulin polymerization promoting protein family member 3 Homo sapiens 14-19 33082910-5 2020 TPPP3 silencing inhibited PA overload-induced apoptosis and production of ROS, along with the alteration of apoptosis-related key proteins such as BCL-2 and Bax. Protactinium 26-28 tubulin polymerization promoting protein family member 3 Homo sapiens 0-5 33082910-5 2020 TPPP3 silencing inhibited PA overload-induced apoptosis and production of ROS, along with the alteration of apoptosis-related key proteins such as BCL-2 and Bax. Reactive Oxygen Species 74-77 tubulin polymerization promoting protein family member 3 Homo sapiens 0-5 33082910-7 2020 Further studies indicated that TPPP3 could promote apoptosis, ROS production, tube formation, and proapoptotic protein expression and reduce antiapoptotic protein expression through increasing VDAC1 expression under mildly elevated levels of PA. Reactive Oxygen Species 62-65 tubulin polymerization promoting protein family member 3 Homo sapiens 31-36 33082910-8 2020 Collectively, these results demonstrated that TPPP3 could promote PA-induced oxidative damage in HUVECs via a VDAC1-dependent pathway, suggesting that TPPP3 might be considered as a potential therapeutic target in vascular disease. Protactinium 66-68 tubulin polymerization promoting protein family member 3 Homo sapiens 46-51 33082910-8 2020 Collectively, these results demonstrated that TPPP3 could promote PA-induced oxidative damage in HUVECs via a VDAC1-dependent pathway, suggesting that TPPP3 might be considered as a potential therapeutic target in vascular disease. Protactinium 66-68 tubulin polymerization promoting protein family member 3 Homo sapiens 151-156 30923531-1 2019 Orthocaspases are prokaryotic caspase homologs - proteases, which cleave their substrates after positively charged residues using a conserved histidine - cysteine (HC) dyad situated in a catalytic p20 domain. histidine - cysteine 142-162 tubulin polymerization promoting protein family member 3 Homo sapiens 197-200 31775905-8 2019 Furthermore, SAA stimulation induced cleaved caspase-1 (p20) secretion from human neutrophils, and this release was suppressed by HCQ pretreatment. Hydroxychloroquine 130-133 tubulin polymerization promoting protein family member 3 Homo sapiens 56-59 30945564-8 2019 Mechanistically, we show that vildagliptin suppresses FFA-induced expression of proteins of the NLRP3 inflammasome complex, including NLRP3, ASC, p20 and HMGB-1, and mitigates FFA-induced inactivation of the AMPK pathway. Vildagliptin 30-42 tubulin polymerization promoting protein family member 3 Homo sapiens 146-149 30945564-8 2019 Mechanistically, we show that vildagliptin suppresses FFA-induced expression of proteins of the NLRP3 inflammasome complex, including NLRP3, ASC, p20 and HMGB-1, and mitigates FFA-induced inactivation of the AMPK pathway. Fatty Acids, Nonesterified 54-57 tubulin polymerization promoting protein family member 3 Homo sapiens 146-149 30157949-9 2018 Tofacitinib, which inhibits GM-CSF-induced Janus kinase 2 (Jak2)-mediated signal transduction, completely abrogated GM-CSF-induced IL-1beta and caspase-1 (p20) secretion from neutrophils. tofacitinib 0-11 tubulin polymerization promoting protein family member 3 Homo sapiens 155-158 27876652-5 2017 When combining the two age groups (P20+P40), the animals exposed to isoflurane had 3.6 times as many apoptotic cells as the control animals. Isoflurane 68-78 tubulin polymerization promoting protein family member 3 Homo sapiens 35-38 28642458-6 2017 Very high concentrations of boron (x 1), give rise to a soft (Vickers hardness of ~8 GPa) and unstable hP20-WB4 structure that can be considered to be built of quasi-planar boron alpha-sheets separated by graphitic tungsten layers. Boron 28-33 tubulin polymerization promoting protein family member 3 Homo sapiens 105-109 28642458-6 2017 Very high concentrations of boron (x 1), give rise to a soft (Vickers hardness of ~8 GPa) and unstable hP20-WB4 structure that can be considered to be built of quasi-planar boron alpha-sheets separated by graphitic tungsten layers. Boron 175-180 tubulin polymerization promoting protein family member 3 Homo sapiens 105-109 29084149-4 2017 H2O2 generation underwent progressive increases in MEM1-incubated P20 and P30 cells, peaking in the latter, but was gradually lowered in those incubated with MEM2-MEM8, reaching its lowest values when cells were incubated with MEM7 and MEM8. Hydrogen Peroxide 0-4 tubulin polymerization promoting protein family member 3 Homo sapiens 66-69 27287014-5 2016 Hydroxytyrosol-treated P20 cells significantly (P < 0.05) increased expression of genes involved in inhibition of adipogenesis, such as GATA2, GATA3, WNT3A, SFRP5, HES1, and SIRT1. 3,4-dihydroxyphenylethanol 0-14 tubulin polymerization promoting protein family member 3 Homo sapiens 23-26 27876872-4 2016 The TGA results indicated that the PM produced by P20 had the highest moisture and volatility contents and the fastest oxidation rate of solid carbon followed by P10 and P0 derived PM. Carbon 143-149 tubulin polymerization promoting protein family member 3 Homo sapiens 50-53 27287014-4 2016 The treatment with hydroxytyrosol extract significantly (P < 0.001) increased apoptosis in P10 and P20 cells in comparison to control and A7 cells; significantly (P < 0.001) reduced triglyceride accumulation in P20 cells compared to P10 and control cells; and significantly (P < 0.001) increased lipolysis in P20 cells in comparison to control cells and A7 mature adipocytes. 3,4-dihydroxyphenylethanol 19-33 tubulin polymerization promoting protein family member 3 Homo sapiens 102-105 25564485-6 2015 Moreover, maitotoxin, which increases intracellular calcium levels and activates calpain activity, induced the intracellular proteolysis of p34 into p20, p26 and p28 and the cleavage of p43, p50 and p84 into p38 and a novel protein, p34c. maitotoxin 10-20 tubulin polymerization promoting protein family member 3 Homo sapiens 149-152 27287014-4 2016 The treatment with hydroxytyrosol extract significantly (P < 0.001) increased apoptosis in P10 and P20 cells in comparison to control and A7 cells; significantly (P < 0.001) reduced triglyceride accumulation in P20 cells compared to P10 and control cells; and significantly (P < 0.001) increased lipolysis in P20 cells in comparison to control cells and A7 mature adipocytes. 3,4-dihydroxyphenylethanol 19-33 tubulin polymerization promoting protein family member 3 Homo sapiens 217-220 27287014-4 2016 The treatment with hydroxytyrosol extract significantly (P < 0.001) increased apoptosis in P10 and P20 cells in comparison to control and A7 cells; significantly (P < 0.001) reduced triglyceride accumulation in P20 cells compared to P10 and control cells; and significantly (P < 0.001) increased lipolysis in P20 cells in comparison to control cells and A7 mature adipocytes. 3,4-dihydroxyphenylethanol 19-33 tubulin polymerization promoting protein family member 3 Homo sapiens 217-220 26909644-7 2016 P20 peptide caused dose-dependent relaxation of carbachol-precontracted ASM and blocked carbachol-induced contraction. Carbachol 48-57 tubulin polymerization promoting protein family member 3 Homo sapiens 0-3 26909644-7 2016 P20 peptide caused dose-dependent relaxation of carbachol-precontracted ASM and blocked carbachol-induced contraction. Carbachol 88-97 tubulin polymerization promoting protein family member 3 Homo sapiens 0-3 27540349-6 2016 Treatments with CF, DHA and OL significantly incremented lipolysis in P20 cells in comparison to other compounds and in CTRL cells. Docosahexaenoic Acids 20-23 tubulin polymerization promoting protein family member 3 Homo sapiens 70-73 27540349-6 2016 Treatments with CF, DHA and OL significantly incremented lipolysis in P20 cells in comparison to other compounds and in CTRL cells. oleuropein 28-30 tubulin polymerization promoting protein family member 3 Homo sapiens 70-73 26865578-3 2016 Baicalin at 50 microg/ml and 100 microg/ml could inhibit the production of ROS, TNF-alpha, IL-1beta and IL-18, and down-regulate mRNA expression of IL-1beta, IL-18, TNF-alpha and NLRP3, as well as expression of cleaved caspase-1 p20. baicalin 0-8 tubulin polymerization promoting protein family member 3 Homo sapiens 229-232 25471594-6 2015 RESULTS: In the overall group, the combination creatinine and cystatin C equation had 69% of results within 20% of GFR (P20), a sensitivity of 86.3% and a specificity of 73.1% to detect reduced GFR at <90 mL/min/1.73 m(2), and a concordance of 78%. Creatinine 47-57 tubulin polymerization promoting protein family member 3 Homo sapiens 120-123 24491357-6 2014 By immunoblot analysis, we found that the levels of procaspases-3 and -7 were lower in TBTO-treated cells; in contrast, the level of p20, the active form of caspase 3, was relatively higher in the treated cells compared to that of control cells. bis(tri-n-butyltin)oxide 87-91 tubulin polymerization promoting protein family member 3 Homo sapiens 133-136 25064367-7 2014 Furthermore, the domains responsible for CP and p20 self-interactions were mapped at the CP amino acids sites 41-84 and p20 amino acids sites 1-21 by Y2H. cp amino acids 89-103 tubulin polymerization promoting protein family member 3 Homo sapiens 48-51 22911690-7 2012 Nicotine increased P20 amplitude, while DHbetaE blocked nicotine-induced enhancements in P20 amplitude. Nicotine 0-8 tubulin polymerization promoting protein family member 3 Homo sapiens 19-22 24794451-6 2014 RESULTS: there were statistically significant differences in P20 group in MAP, pH, HCO3 and BE, but within normal limits. Bicarbonates 83-87 tubulin polymerization promoting protein family member 3 Homo sapiens 61-64 24794451-6 2014 RESULTS: there were statistically significant differences in P20 group in MAP, pH, HCO3 and BE, but within normal limits. Beryllium 92-94 tubulin polymerization promoting protein family member 3 Homo sapiens 61-64 22679876-1 2012 The objective of this study was to investigate the effects of three fragrance fixatives, Glucam P-20, Vanillin, and Fixolide, on the mosquito repellent property of citronella oil lotions. citronella oil 164-178 tubulin polymerization promoting protein family member 3 Homo sapiens 96-100 24613657-11 2014 Finally, MK128 reduced the quantity of p20 caspase-1 produced in the culture medium. mk128 9-14 tubulin polymerization promoting protein family member 3 Homo sapiens 39-42 23551718-1 2013 Injury of the CA1 subregion induced by a single injection of kainic acid (1 x KA) in juvenile animals (P20) is attenuated in animals with two prior sustained neonatal seizures on P6 and P9. Kainic Acid 61-72 tubulin polymerization promoting protein family member 3 Homo sapiens 103-106 21965537-4 2012 Recombinant P20 (rP20) was phosphorylated by host cellular kinase(s) in vitro, and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and mutational analyses revealed Ser-11 as the phosphorylation site. Serine 193-196 tubulin polymerization promoting protein family member 3 Homo sapiens 12-15 22911690-7 2012 Nicotine increased P20 amplitude, while DHbetaE blocked nicotine-induced enhancements in P20 amplitude. Dihydro-beta-Erythroidine 40-47 tubulin polymerization promoting protein family member 3 Homo sapiens 89-92 22911690-7 2012 Nicotine increased P20 amplitude, while DHbetaE blocked nicotine-induced enhancements in P20 amplitude. Nicotine 56-64 tubulin polymerization promoting protein family member 3 Homo sapiens 89-92 22911690-12 2012 CONCLUSIONS/SIGNIFICANCE: These results support findings showing that nicotine-induced augmentation of P20 amplitude occurs via a DHbetaE sensitive mechanism, but suggests that this does not occur through activation of alpha4beta2 receptors. Nicotine 70-78 tubulin polymerization promoting protein family member 3 Homo sapiens 103-106 21869626-11 2011 A significant postexercise decrease was observed for alpha-tocopherol (p < 0.05) at P20 for judokas and at P5 for sedentary subjects. alpha-Tocopherol 53-69 tubulin polymerization promoting protein family member 3 Homo sapiens 87-90 22911690-12 2012 CONCLUSIONS/SIGNIFICANCE: These results support findings showing that nicotine-induced augmentation of P20 amplitude occurs via a DHbetaE sensitive mechanism, but suggests that this does not occur through activation of alpha4beta2 receptors. Dihydro-beta-Erythroidine 130-137 tubulin polymerization promoting protein family member 3 Homo sapiens 103-106 22378001-4 2012 Under the conditions of Ca/P 2.0, pH 8.5 and 10 mg P/L, the phosphate crystallization occurred during 12 h. The quartz sand and ceramsite did not improve the phosphate crystallization, but steel slag was an effective seed crystal. Phosphates 60-69 tubulin polymerization promoting protein family member 3 Homo sapiens 27-32 21499934-6 2011 Pure oxygen was experimentally shown, for the first time, to affect the human brain activation, at the beginning of early P20 sensory cortical activation and late N100 auditory perception. Oxygen 5-11 tubulin polymerization promoting protein family member 3 Homo sapiens 122-125 21527846-5 2011 Berberine also led to the generation of the p20 cleavage fragment of BAP31, involved in directing proapoptotic signals between the endoplasmic reticulum and the mitochondria. Berberine 0-9 tubulin polymerization promoting protein family member 3 Homo sapiens 44-47 21291934-7 2011 Interestingly, when p20 was tested against the very aggressive bacterial pathogen Piscirickettsia salmonis, a common co-infectant of IPNV in salmonid fish, the specific activity of the novel peptide was significantly higher than that displayed for bactericidal fish farm antibiotics such as oxolinic acid, flumequine and florfenicol, which are commonly used to control Piscirickettsiosis in the field. Oxolinic Acid 291-304 tubulin polymerization promoting protein family member 3 Homo sapiens 20-23 21291934-7 2011 Interestingly, when p20 was tested against the very aggressive bacterial pathogen Piscirickettsia salmonis, a common co-infectant of IPNV in salmonid fish, the specific activity of the novel peptide was significantly higher than that displayed for bactericidal fish farm antibiotics such as oxolinic acid, flumequine and florfenicol, which are commonly used to control Piscirickettsiosis in the field. flumequine 306-316 tubulin polymerization promoting protein family member 3 Homo sapiens 20-23 21291934-7 2011 Interestingly, when p20 was tested against the very aggressive bacterial pathogen Piscirickettsia salmonis, a common co-infectant of IPNV in salmonid fish, the specific activity of the novel peptide was significantly higher than that displayed for bactericidal fish farm antibiotics such as oxolinic acid, flumequine and florfenicol, which are commonly used to control Piscirickettsiosis in the field. florfenicol 321-332 tubulin polymerization promoting protein family member 3 Homo sapiens 20-23 20695836-5 2010 MATERIAL AND METHODS: Expression of the non-structural norovirus protein p20 in the epithelial cell line HT-29/B6 was activated through a tetracycline sensitive promoter. Tetracycline 138-150 tubulin polymerization promoting protein family member 3 Homo sapiens 73-76 20829366-7 2010 In multivariate regression analyses, adjusting for maternal and child characteristics, higher newborn TSH concentrations showed a decrease of 3.51 and 3.15 points on the MSCA general cognitive and executive function scores respectively and were associated with a higher risk of scoring below the 20th percentile (P20) on the quantitative score (odds ratio (OR)=2.64). Thyrotropin 102-105 tubulin polymerization promoting protein family member 3 Homo sapiens 313-316 18164959-6 2008 RESULTS: We show that RSVL cleaved the immature caspase-3 (35 kDa) into the active fragments (p12, p17, p20) in a dose- and time-dependent manner. Resveratrol 22-26 tubulin polymerization promoting protein family member 3 Homo sapiens 104-107 18687314-3 2008 A previous study using an animal model, deficient P20-N40 (which corresponds to the human P50) inhibitory processing in DBA/2 mice found that sensory inhibition was improved by clozapine, the prototypical atypical antipsychotic, but not by haloperidol, a typical antipsychotic. Clozapine 177-186 tubulin polymerization promoting protein family member 3 Homo sapiens 50-53 18687314-3 2008 A previous study using an animal model, deficient P20-N40 (which corresponds to the human P50) inhibitory processing in DBA/2 mice found that sensory inhibition was improved by clozapine, the prototypical atypical antipsychotic, but not by haloperidol, a typical antipsychotic. Haloperidol 240-251 tubulin polymerization promoting protein family member 3 Homo sapiens 50-53 18687314-7 2008 All doses of olanzapine produced improved P20-N40 inhibitory processing in DBA/2 mice. Olanzapine 13-23 tubulin polymerization promoting protein family member 3 Homo sapiens 42-45 17554035-5 2007 In contrast, peptides bearing Glu-Gly at the scissile bond (p20/VPg and 3C(pro)/3D(pol) junctions) were resistant to trans-cleavage by 3C(pro) and 3CD(propol). Glutamic Acid 30-33 tubulin polymerization promoting protein family member 3 Homo sapiens 60-63 17651747-3 2007 Derivatives of P20 were prepared by conjugation to bovine serum albumin (BSA-P20ACM) or biotin (Biot-P20ACM). Biotin 88-94 tubulin polymerization promoting protein family member 3 Homo sapiens 15-18 17974980-8 2007 Edelfosine treatment led to the generation of the p20 caspase-8 cleavage fragment of BAP31, directing proapoptotic signals between the ER and the mitochondria. edelfosine 0-10 tubulin polymerization promoting protein family member 3 Homo sapiens 50-53 17554035-5 2007 In contrast, peptides bearing Glu-Gly at the scissile bond (p20/VPg and 3C(pro)/3D(pol) junctions) were resistant to trans-cleavage by 3C(pro) and 3CD(propol). Glycine 34-37 tubulin polymerization promoting protein family member 3 Homo sapiens 60-63 16678050-0 2006 HYTAD1-p20: a new paclitaxel-hyaluronic acid hydrosoluble bioconjugate for treatment of superficial bladder cancer. Paclitaxel 18-28 tubulin polymerization promoting protein family member 3 Homo sapiens 7-10 17651747-3 2007 Derivatives of P20 were prepared by conjugation to bovine serum albumin (BSA-P20ACM) or biotin (Biot-P20ACM). biot-p20acm 96-107 tubulin polymerization promoting protein family member 3 Homo sapiens 15-18 16838788-0 2006 The arginine-rich motif of Bamboo mosaic virus satellite RNA-encoded P20 mediates self-interaction, intracellular targeting, and cell-to-cell movement. Arginine 4-12 tubulin polymerization promoting protein family member 3 Homo sapiens 69-72 16838788-4 2006 Domain mapping, using the bacterial two-hybrid system, indicated that the self-interacting domain overlaps the RNA-binding domain in the N-terminal arginine-rich motif (ARM) of P20. Arginine 148-156 tubulin polymerization promoting protein family member 3 Homo sapiens 177-180 16678050-0 2006 HYTAD1-p20: a new paclitaxel-hyaluronic acid hydrosoluble bioconjugate for treatment of superficial bladder cancer. hyaluronic acid hydrosoluble 29-57 tubulin polymerization promoting protein family member 3 Homo sapiens 7-10 16678050-1 2006 OBJECTIVE: To report the development of a new water-soluble paclitaxel-hyaluronic acid bioconjugate, HYTAD1-p20, for intravesical treatment of superficial bladder cancer. Water 46-51 tubulin polymerization promoting protein family member 3 Homo sapiens 108-111 16678050-1 2006 OBJECTIVE: To report the development of a new water-soluble paclitaxel-hyaluronic acid bioconjugate, HYTAD1-p20, for intravesical treatment of superficial bladder cancer. Paclitaxel 60-70 tubulin polymerization promoting protein family member 3 Homo sapiens 108-111 16678050-1 2006 OBJECTIVE: To report the development of a new water-soluble paclitaxel-hyaluronic acid bioconjugate, HYTAD1-p20, for intravesical treatment of superficial bladder cancer. Hyaluronic Acid 71-86 tubulin polymerization promoting protein family member 3 Homo sapiens 108-111 16678050-2 2006 MATERIALS AND METHODS: HYTAD1-p20 was synthesized by carboxyl esterification of hyaluronic acid with paclitaxel, and its physicochemical and biologic properties were characterized. Hyaluronic Acid 80-95 tubulin polymerization promoting protein family member 3 Homo sapiens 30-33 16678050-2 2006 MATERIALS AND METHODS: HYTAD1-p20 was synthesized by carboxyl esterification of hyaluronic acid with paclitaxel, and its physicochemical and biologic properties were characterized. Paclitaxel 101-111 tubulin polymerization promoting protein family member 3 Homo sapiens 30-33 16678050-8 2006 CONCLUSIONS: These data suggest that HYTAD1-p20 significantly improved results obtained with conventional paclitaxel in terms of hydrosolubility, in vitro activity against human bladder cancer cells, and in vivo biocompatibility. Paclitaxel 106-116 tubulin polymerization promoting protein family member 3 Homo sapiens 44-47 16169517-1 2005 A CYP2D7 brain-specific protein metabolizing codeine and encoded by an alternate mRNA has recently been described in Indian subjects. Codeine 45-52 tubulin polymerization promoting protein family member 3 Homo sapiens 9-31 16343612-4 2006 In this report the laminin fragments CDPGYIGSR (p31) and RNIAEIIKDI (p20) are used as dopants in electropolymerization of the conducting polymer polypyrrole (PPy). polypyrrole 145-156 tubulin polymerization promoting protein family member 3 Homo sapiens 69-72 16343612-4 2006 In this report the laminin fragments CDPGYIGSR (p31) and RNIAEIIKDI (p20) are used as dopants in electropolymerization of the conducting polymer polypyrrole (PPy). Polymers 104-111 tubulin polymerization promoting protein family member 3 Homo sapiens 69-72 15358169-2 2004 Proline substitution of single residues in the P16-P20 region (situated at the proximal hinge of the reactive site loop) of wild-type PAI-1 (wtPAI-1) and a stabilized PAI-1-variant (PAI-1-stab; N150H, K154T, Q301P, Q319L, and M354I, t(1/2)=150), respectively, resulted in two series of PAI-1-variants with different properties. Proline 0-7 tubulin polymerization promoting protein family member 3 Homo sapiens 51-54 12243905-3 2002 Only three Pseudomonas strains were able to transfer electrons resulting from specific oxidation of phenol to the electrode by means of mediators; ferrocene, duroquinone and dimethyferrocene were successfully used with the strains 394 (p20), 74-III and 83-IV (working names), respectively. ferrocene 147-156 tubulin polymerization promoting protein family member 3 Homo sapiens 236-239 12529377-2 2003 Upon Fas/CD95 stimulation, BAP31 is cleaved within its cytosolic domain, generating proapoptotic p20 BAP31. ammonium ferrous sulfate 5-8 tubulin polymerization promoting protein family member 3 Homo sapiens 97-100 12588350-4 2003 Serine and threonine phosphorylations of the myosin light chain (P20) and pleckstrin (P47) do not behave similarly, although they are both recognized as the result of phospholipase C pathway stimulation triggered by the P2Y1 receptor. Serine 0-6 tubulin polymerization promoting protein family member 3 Homo sapiens 65-68 12588350-4 2003 Serine and threonine phosphorylations of the myosin light chain (P20) and pleckstrin (P47) do not behave similarly, although they are both recognized as the result of phospholipase C pathway stimulation triggered by the P2Y1 receptor. Threonine 11-20 tubulin polymerization promoting protein family member 3 Homo sapiens 65-68 12243905-3 2002 Only three Pseudomonas strains were able to transfer electrons resulting from specific oxidation of phenol to the electrode by means of mediators; ferrocene, duroquinone and dimethyferrocene were successfully used with the strains 394 (p20), 74-III and 83-IV (working names), respectively. dimethyferrocene 174-190 tubulin polymerization promoting protein family member 3 Homo sapiens 236-239 12243905-4 2002 The lower limits for detection of phenol were 1 micro M for the strain 74-III and 10 micro M for the strain 83-IV and 394 (p20). Phenol 34-40 tubulin polymerization promoting protein family member 3 Homo sapiens 123-126 12133589-5 2002 After lorazepam administration, conventional scalp SEPs showed a significant amplitude decrease of all cortical components including the primary N20/P20 response, while the subcortical P14 response remained substantially unchanged. Lorazepam 6-15 tubulin polymerization promoting protein family member 3 Homo sapiens 149-152 11981240-6 2002 SSEP changes resulting from amantadine sulfate treatment were observed in the P20-N30 amplitude as follows: Mean P20-N30 amplitudes before and after treatment were 2.15 +/- 1.11 microV and 3.06 +/- 1.19 microV respectively (p = 0.000), whereas mean N30-P40 amplitude increased from 2.7 +/- 1.6 microV to 3.9 +/- 1.3 microV after treatment (p = 0.000). Amantadine 28-46 tubulin polymerization promoting protein family member 3 Homo sapiens 78-81 11981240-6 2002 SSEP changes resulting from amantadine sulfate treatment were observed in the P20-N30 amplitude as follows: Mean P20-N30 amplitudes before and after treatment were 2.15 +/- 1.11 microV and 3.06 +/- 1.19 microV respectively (p = 0.000), whereas mean N30-P40 amplitude increased from 2.7 +/- 1.6 microV to 3.9 +/- 1.3 microV after treatment (p = 0.000). Amantadine 28-46 tubulin polymerization promoting protein family member 3 Homo sapiens 113-116 11880018-5 2002 INTERVENTIONS: After epidural anesthesia, propofol was infused at 20 mg/kg/hr (P20) for 4 to 5 minutes followed by 5 mg/kg/hr (P5), and nasal continuous positive airway pressure (CPAP) 8 cm H(2)O and BiPAP 14/8 cm H(2)O was applied. Propofol 42-50 tubulin polymerization promoting protein family member 3 Homo sapiens 75-82 11880018-5 2002 INTERVENTIONS: After epidural anesthesia, propofol was infused at 20 mg/kg/hr (P20) for 4 to 5 minutes followed by 5 mg/kg/hr (P5), and nasal continuous positive airway pressure (CPAP) 8 cm H(2)O and BiPAP 14/8 cm H(2)O was applied. Propofol 42-50 tubulin polymerization promoting protein family member 3 Homo sapiens 75-78 11181841-5 2001 Reaction of human recombinant tau with tau protein kinase II (cdk5/p20) resulted in the formation of two major species containing either five or six phosphate groups. Phosphates 149-158 tubulin polymerization promoting protein family member 3 Homo sapiens 67-70 11475894-4 2001 After introducing a methylene group into the hydrophilic moiety of the trapencaine molecule (stereoisomers P-18, P-20), there was a loss of antiradical activity, but the cis-isomer is more effective than the transisomer. pentacaine 71-82 tubulin polymerization promoting protein family member 3 Homo sapiens 113-117 11512838-2 2001 In this study, pitch-based activated carbon fibers (P20) were modified with nickel oxide particles. Carbon 37-43 tubulin polymerization promoting protein family member 3 Homo sapiens 52-55 11512838-2 2001 In this study, pitch-based activated carbon fibers (P20) were modified with nickel oxide particles. nickel monoxide 76-88 tubulin polymerization promoting protein family member 3 Homo sapiens 52-55 11512838-3 2001 The adsorptive properties and micropore structures of NiO dispersed P20 (NiO-P20) were investigated by nitrogen adsorption isotherms at 77 K. The isotherm was of type 1, suggesting that the NiO-P20 has microporosity. Nitrogen 103-111 tubulin polymerization promoting protein family member 3 Homo sapiens 68-71 11512838-4 2001 The micropore volume and surface area for NiO-dispersed P20 were smaller than that of P20 by about 15%. nio 42-45 tubulin polymerization promoting protein family member 3 Homo sapiens 56-59 11512838-6 2001 The local structure of the NiO particles on the P20 showed some different features compared with the local structure of powdered NiO. nio 27-30 tubulin polymerization promoting protein family member 3 Homo sapiens 48-51 11181841-7 2001 Based on these experiments, we conclude that tau protein kinase II (cdk5/p20) can phosphorylate human tau at Thr(181), Thr(205), Thr(212), Thr(217), Ser(396) and Ser(404). Threonine 109-112 tubulin polymerization promoting protein family member 3 Homo sapiens 73-76 11181841-7 2001 Based on these experiments, we conclude that tau protein kinase II (cdk5/p20) can phosphorylate human tau at Thr(181), Thr(205), Thr(212), Thr(217), Ser(396) and Ser(404). Threonine 119-122 tubulin polymerization promoting protein family member 3 Homo sapiens 73-76 11181841-7 2001 Based on these experiments, we conclude that tau protein kinase II (cdk5/p20) can phosphorylate human tau at Thr(181), Thr(205), Thr(212), Thr(217), Ser(396) and Ser(404). Threonine 119-122 tubulin polymerization promoting protein family member 3 Homo sapiens 73-76 11181841-7 2001 Based on these experiments, we conclude that tau protein kinase II (cdk5/p20) can phosphorylate human tau at Thr(181), Thr(205), Thr(212), Thr(217), Ser(396) and Ser(404). Threonine 119-122 tubulin polymerization promoting protein family member 3 Homo sapiens 73-76 11181841-7 2001 Based on these experiments, we conclude that tau protein kinase II (cdk5/p20) can phosphorylate human tau at Thr(181), Thr(205), Thr(212), Thr(217), Ser(396) and Ser(404). Serine 149-152 tubulin polymerization promoting protein family member 3 Homo sapiens 73-76 11181841-7 2001 Based on these experiments, we conclude that tau protein kinase II (cdk5/p20) can phosphorylate human tau at Thr(181), Thr(205), Thr(212), Thr(217), Ser(396) and Ser(404). Serine 162-165 tubulin polymerization promoting protein family member 3 Homo sapiens 73-76 10934034-8 2000 In the presence of z-DEVD-FMK or Ac-YVAD-CMK, caspase-3 was processed to both the p17 and p20 fragments in staurosporine-treated cells, but only to p20 fragment in the presence of z-VAD-FMK. benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone 19-29 tubulin polymerization promoting protein family member 3 Homo sapiens 148-151 10934034-8 2000 In the presence of z-DEVD-FMK or Ac-YVAD-CMK, caspase-3 was processed to both the p17 and p20 fragments in staurosporine-treated cells, but only to p20 fragment in the presence of z-VAD-FMK. benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone 19-29 tubulin polymerization promoting protein family member 3 Homo sapiens 90-93 11078888-4 2000 Interestingly, Ac-DEVD-CHO, a caspase-3-like protease inhibitor, blocked not only the decreases in caspase-2 and -7, but also the formation of p17 from p20 in caspase-3 induced by NO, suggesting that caspase-3 exists upstream of caspase-2 and -7. acetyl-aspartyl-glutamyl-valyl-aspartal 15-26 tubulin polymerization promoting protein family member 3 Homo sapiens 152-155 10934034-8 2000 In the presence of z-DEVD-FMK or Ac-YVAD-CMK, caspase-3 was processed to both the p17 and p20 fragments in staurosporine-treated cells, but only to p20 fragment in the presence of z-VAD-FMK. ac-yvad 33-40 tubulin polymerization promoting protein family member 3 Homo sapiens 90-93 10934034-8 2000 In the presence of z-DEVD-FMK or Ac-YVAD-CMK, caspase-3 was processed to both the p17 and p20 fragments in staurosporine-treated cells, but only to p20 fragment in the presence of z-VAD-FMK. ac-yvad 33-40 tubulin polymerization promoting protein family member 3 Homo sapiens 148-151 10934034-8 2000 In the presence of z-DEVD-FMK or Ac-YVAD-CMK, caspase-3 was processed to both the p17 and p20 fragments in staurosporine-treated cells, but only to p20 fragment in the presence of z-VAD-FMK. Staurosporine 107-120 tubulin polymerization promoting protein family member 3 Homo sapiens 90-93 10658410-5 1999 Thirty min after the treatment on the cuffs, P20 of the tubes with lidocaine spray significantly decreased than that of the control tubes with normal saline. Lidocaine 67-76 tubulin polymerization promoting protein family member 3 Homo sapiens 45-48 9870481-3 1998 We have previously demonstrated an enhancement of agonist-mediated platelet activation by cyclosporine and tacrolimus which was associated with increased phosphorylation of two intracellular platelet proteins, p20 and p40. Cyclosporine 90-102 tubulin polymerization promoting protein family member 3 Homo sapiens 210-213 10318842-4 1999 p35-C/EBPbeta activates transcription of the SRE in an SRF-dependent fashion, whereas p20-C/EBPbeta, which initiates at an internal in-frame methionine, lacks a transactivation domain and inhibits transcription. Methionine 141-151 tubulin polymerization promoting protein family member 3 Homo sapiens 86-89 9870481-3 1998 We have previously demonstrated an enhancement of agonist-mediated platelet activation by cyclosporine and tacrolimus which was associated with increased phosphorylation of two intracellular platelet proteins, p20 and p40. Tacrolimus 107-117 tubulin polymerization promoting protein family member 3 Homo sapiens 210-213 9771651-4 1998 Incubation of sperm in vitro for various periods of time induced an increase of tyrosine phosphorylation of p20, p93, and p175. Tyrosine 80-88 tubulin polymerization promoting protein family member 3 Homo sapiens 108-111 9771651-5 1998 The tyrosine phosphorylation of p93, p175, and several other sperm proteins was up-regulated in a concentration-dependent manner following treatment of the sperm with dbcAMP, caffeine, or IBMX alone, or with combinations of caffeine and IBMX, respectively, with dbcAMP; the tyrosine phosphorylation of p20 was not correlated with treatment of sperm with cAMP-elevating reagents. Tyrosine 4-12 tubulin polymerization promoting protein family member 3 Homo sapiens 302-305 9771651-5 1998 The tyrosine phosphorylation of p93, p175, and several other sperm proteins was up-regulated in a concentration-dependent manner following treatment of the sperm with dbcAMP, caffeine, or IBMX alone, or with combinations of caffeine and IBMX, respectively, with dbcAMP; the tyrosine phosphorylation of p20 was not correlated with treatment of sperm with cAMP-elevating reagents. Bucladesine 167-173 tubulin polymerization promoting protein family member 3 Homo sapiens 302-305 9771651-5 1998 The tyrosine phosphorylation of p93, p175, and several other sperm proteins was up-regulated in a concentration-dependent manner following treatment of the sperm with dbcAMP, caffeine, or IBMX alone, or with combinations of caffeine and IBMX, respectively, with dbcAMP; the tyrosine phosphorylation of p20 was not correlated with treatment of sperm with cAMP-elevating reagents. Caffeine 175-183 tubulin polymerization promoting protein family member 3 Homo sapiens 302-305 9771651-5 1998 The tyrosine phosphorylation of p93, p175, and several other sperm proteins was up-regulated in a concentration-dependent manner following treatment of the sperm with dbcAMP, caffeine, or IBMX alone, or with combinations of caffeine and IBMX, respectively, with dbcAMP; the tyrosine phosphorylation of p20 was not correlated with treatment of sperm with cAMP-elevating reagents. 1-Methyl-3-isobutylxanthine 188-192 tubulin polymerization promoting protein family member 3 Homo sapiens 302-305 9771651-11 1998 On the other hand, the tyrosine phosphorylation of p20 (and potentially other triton-soluble substrates) might not strictly require such cAMP up-regulation. Tyrosine 23-31 tubulin polymerization promoting protein family member 3 Homo sapiens 51-54 9771651-11 1998 On the other hand, the tyrosine phosphorylation of p20 (and potentially other triton-soluble substrates) might not strictly require such cAMP up-regulation. Cyclic AMP 137-141 tubulin polymerization promoting protein family member 3 Homo sapiens 51-54 9628417-7 1998 The second perirolandic dipole showed an initial peak of activity slightly earlier than that of the N20/P20 dipolar source and, later, it was active at the same latency as the central P22 potential. perirolandic dipole 11-30 tubulin polymerization promoting protein family member 3 Homo sapiens 104-107 9357850-8 1997 Additionally, an increased formation of the active p20 fragments of ICE and Ich-1L as well as degradation of the inactive zymogen form of cpp32beta protein were observed in silica-treated human alveolar macrophages, indicating activation of these proteases. Silicon Dioxide 173-179 tubulin polymerization promoting protein family member 3 Homo sapiens 51-54 9378547-7 1997 c-myc can also form transcriptionally active heterodimeric complexes with the nuclear phosphoproteins p20/p22 max: thus, TPA treatment resulted in down-regulation of the p20 form of max in TUR cells. Tetradecanoylphorbol Acetate 121-124 tubulin polymerization promoting protein family member 3 Homo sapiens 102-105 9378547-7 1997 c-myc can also form transcriptionally active heterodimeric complexes with the nuclear phosphoproteins p20/p22 max: thus, TPA treatment resulted in down-regulation of the p20 form of max in TUR cells. Tetradecanoylphorbol Acetate 121-124 tubulin polymerization promoting protein family member 3 Homo sapiens 170-173 9201980-3 1997 We have recently described the isolation of a protein p20-CGGBP that binds sequence-specifically to the double-stranded trinucleotide repeat 5"-d(CGG)-3" (Deissler, H., Behn-Krappa, A., and Doerfler, W. (1996) J. Biol. trinucleotide 120-133 tubulin polymerization promoting protein family member 3 Homo sapiens 54-57