PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
8761454-6	1996	In addition, iron-induced increases in ferritin mRNA abundance were the same as wild-type plants in abi1 and abi2 mutants of A. thaliana, both affected in the abscisic acid response in vegetative tissues.	Iron	13-17	Protein phosphatase 2C family protein	Arabidopsis thaliana	109-113
9165752-0	1997	The Arabidopsis ABSCISIC ACID-INSENSITIVE2 (ABI2) and ABI1 genes encode homologous protein phosphatases 2C involved in abscisic acid signal transduction.	Abscisic Acid	119-132	Protein phosphatase 2C family protein	Arabidopsis thaliana	16-42
9165752-0	1997	The Arabidopsis ABSCISIC ACID-INSENSITIVE2 (ABI2) and ABI1 genes encode homologous protein phosphatases 2C involved in abscisic acid signal transduction.	Abscisic Acid	119-132	Protein phosphatase 2C family protein	Arabidopsis thaliana	44-48
9165752-4	1997	One such homolog turned out to be the ABI2 locus, whose abi2-1 mutation was previously known to decrease ABA sensitivity.	Abscisic Acid	105-108	Protein phosphatase 2C family protein	Arabidopsis thaliana	38-42
9165752-4	1997	One such homolog turned out to be the ABI2 locus, whose abi2-1 mutation was previously known to decrease ABA sensitivity.	Abscisic Acid	105-108	Protein phosphatase 2C family protein	Arabidopsis thaliana	56-60
9165752-7	1997	In vitro assays and functional complementation studies in yeast confirmed that the ABI2 protein is an active protein phosphatase 2C and that the abi2-1 mutation reduced phosphatase activity as well as affinity to Mg2+.	magnesium ion	213-217	Protein phosphatase 2C family protein	Arabidopsis thaliana	83-87
9165752-7	1997	In vitro assays and functional complementation studies in yeast confirmed that the ABI2 protein is an active protein phosphatase 2C and that the abi2-1 mutation reduced phosphatase activity as well as affinity to Mg2+.	magnesium ion	213-217	Protein phosphatase 2C family protein	Arabidopsis thaliana	145-149
9165752-9	1997	Thus, the homologous ABI1 and ABI2 phosphatases appear to assume partially redundant functions in ABA signaling, which may provide a mechanism to maintain informational homeostasis.	Abscisic Acid	98-101	Protein phosphatase 2C family protein	Arabidopsis thaliana	30-34
9468303-0	1998	ABI2, a second protein phosphatase 2C involved in abscisic acid signal transduction in Arabidopsis.	Abscisic Acid	50-63	Protein phosphatase 2C family protein	Arabidopsis thaliana	0-4
9468303-1	1998	The abi2-1 (abscisic acid insensitive) mutant of Arabidopsis thaliana shows abscisic acid (ABA) insensitivity with respect to seed germination and vegetative ABA responses.	Abscisic Acid	12-25	Protein phosphatase 2C family protein	Arabidopsis thaliana	4-8
9468303-1	1998	The abi2-1 (abscisic acid insensitive) mutant of Arabidopsis thaliana shows abscisic acid (ABA) insensitivity with respect to seed germination and vegetative ABA responses.	Abscisic Acid	76-89	Protein phosphatase 2C family protein	Arabidopsis thaliana	4-8
9468303-1	1998	The abi2-1 (abscisic acid insensitive) mutant of Arabidopsis thaliana shows abscisic acid (ABA) insensitivity with respect to seed germination and vegetative ABA responses.	Abscisic Acid	91-94	Protein phosphatase 2C family protein	Arabidopsis thaliana	4-8
9468303-1	1998	The abi2-1 (abscisic acid insensitive) mutant of Arabidopsis thaliana shows abscisic acid (ABA) insensitivity with respect to seed germination and vegetative ABA responses.	Abscisic Acid	158-161	Protein phosphatase 2C family protein	Arabidopsis thaliana	4-8
9468303-3	1998	The ABI2 protein shows 80% amino acid sequence identity to ABI1, a protein phosphatase 2C (PP2C) involved in ABA signaling.	Abscisic Acid	109-112	Protein phosphatase 2C family protein	Arabidopsis thaliana	4-8
9276963-1	1997	We show that guard cells from Arabidopsis thaliana plants carrying the abscisic acid-insensitive mutations abi1 and abi2 fail to respond to CO2 and extracellular calcium.	Abscisic Acid	71-84	Protein phosphatase 2C family protein	Arabidopsis thaliana	116-120
9276963-1	1997	We show that guard cells from Arabidopsis thaliana plants carrying the abscisic acid-insensitive mutations abi1 and abi2 fail to respond to CO2 and extracellular calcium.	Calcium	162-169	Protein phosphatase 2C family protein	Arabidopsis thaliana	116-120
9090884-0	1997	Differential abscisic acid regulation of guard cell slow anion channels in Arabidopsis wild-type and abi1 and abi2 mutants.	Abscisic Acid	13-26	Protein phosphatase 2C family protein	Arabidopsis thaliana	110-114
9090884-8	1997	These data provide cell biological evidence that the abi2 locus disrupts early ABA signaling, that abi1 and abi2 affect ABA signaling at different steps in the cascade, and that protein kinases act as negative regulators of ABA signaling in Arabidopsis.	Abscisic Acid	79-82	Protein phosphatase 2C family protein	Arabidopsis thaliana	53-57
9090884-8	1997	These data provide cell biological evidence that the abi2 locus disrupts early ABA signaling, that abi1 and abi2 affect ABA signaling at different steps in the cascade, and that protein kinases act as negative regulators of ABA signaling in Arabidopsis.	Abscisic Acid	120-123	Protein phosphatase 2C family protein	Arabidopsis thaliana	53-57
9090884-8	1997	These data provide cell biological evidence that the abi2 locus disrupts early ABA signaling, that abi1 and abi2 affect ABA signaling at different steps in the cascade, and that protein kinases act as negative regulators of ABA signaling in Arabidopsis.	Abscisic Acid	120-123	Protein phosphatase 2C family protein	Arabidopsis thaliana	108-112
9090884-8	1997	These data provide cell biological evidence that the abi2 locus disrupts early ABA signaling, that abi1 and abi2 affect ABA signaling at different steps in the cascade, and that protein kinases act as negative regulators of ABA signaling in Arabidopsis.	Abscisic Acid	120-123	Protein phosphatase 2C family protein	Arabidopsis thaliana	53-57
9090884-8	1997	These data provide cell biological evidence that the abi2 locus disrupts early ABA signaling, that abi1 and abi2 affect ABA signaling at different steps in the cascade, and that protein kinases act as negative regulators of ABA signaling in Arabidopsis.	Abscisic Acid	120-123	Protein phosphatase 2C family protein	Arabidopsis thaliana	108-112
8761454-6	1996	In addition, iron-induced increases in ferritin mRNA abundance were the same as wild-type plants in abi1 and abi2 mutants of A. thaliana, both affected in the abscisic acid response in vegetative tissues.	Abscisic Acid	159-172	Protein phosphatase 2C family protein	Arabidopsis thaliana	109-113
1834244-7	1991	Our data indicate that the ABA-induced expression of three ABA-regulated Arabidopsis cor genes was unaffected in the abi2, abi3, and aba-1 mutants, but was dramatically impaired in the abi1 mutant.	Abscisic Acid	27-30	Protein phosphatase 2C family protein	Arabidopsis thaliana	117-121
8787023-4	1996	Arabidopsis ABA mutants (aba1 and abi2) displayed reduced Adh mRNA induction levels following either dehydration treatment or exogenous application of ABA.	Abscisic Acid	12-15	Protein phosphatase 2C family protein	Arabidopsis thaliana	34-38
8492808-3	1993	In contrast, the abi1 and abi2 mutants showed a very slight reduction of ABA inducibility in 8-day-old plants, while the responses of aba and abi3 mutants were comparable to that of wild type.	Abscisic Acid	73-76	Protein phosphatase 2C family protein	Arabidopsis thaliana	26-30
8771791-6	1996	Induction levels in two ABA-insensitive mutants abi2 and abi3 were similar to the wild-type response.	Abscisic Acid	24-27	Protein phosphatase 2C family protein	Arabidopsis thaliana	48-52
12232276-3	1994	The effects of the abi1 and abi2 mutations on ABA sensitivity of seed germination ranged from recessive to nearly fully dominant, depending on the parental source of the mutant allele.	Abscisic Acid	46-49	Protein phosphatase 2C family protein	Arabidopsis thaliana	28-32
34932819-8	2022	Our results reveal that ABA signaling regulates actin reorganization to maintain stomatal closure during drought stress and the feedback regulation of PYL1, ABI1 and ABI2 by the CKL2 kinase might fine-tune ABA signaling and affect plant ABA responses.	Abscisic Acid	24-27	Protein phosphatase 2C family protein	Arabidopsis thaliana	166-170
1688209-10	1991	In order to use the system to isolate genes involved in the signal transduction of abscisic acid, we fine-mapped the mutant loci abi-1 and abi-2, which confer abscisic acid insensitivity, relative to RFLPs and isolated the corresponding YACs.	Abscisic Acid	83-96	Protein phosphatase 2C family protein	Arabidopsis thaliana	139-144
1688209-10	1991	In order to use the system to isolate genes involved in the signal transduction of abscisic acid, we fine-mapped the mutant loci abi-1 and abi-2, which confer abscisic acid insensitivity, relative to RFLPs and isolated the corresponding YACs.	Abscisic Acid	159-172	Protein phosphatase 2C family protein	Arabidopsis thaliana	139-144
16667813-1	1990	Wild type and three abscisic acid (ABA)-insensitive mutants of Arabidopsis (ABI1, ABI2, and ABI3) were compared for their ability to respond to ABA for a variety of ABA-inducible responses throughout the life cycle of the plants.	Abscisic Acid	144-147	Protein phosphatase 2C family protein	Arabidopsis thaliana	82-86
16667813-1	1990	Wild type and three abscisic acid (ABA)-insensitive mutants of Arabidopsis (ABI1, ABI2, and ABI3) were compared for their ability to respond to ABA for a variety of ABA-inducible responses throughout the life cycle of the plants.	Abscisic Acid	144-147	Protein phosphatase 2C family protein	Arabidopsis thaliana	82-86
16667813-3	1990	The abi1 and abi2 mutants showed reduced sensitivity to ABA for inhibition of seedling growth, induction of proline accumulation, and alterations in protein synthesis patterns during vegetative growth, but had wild type levels of storage reserves.	Abscisic Acid	56-59	Protein phosphatase 2C family protein	Arabidopsis thaliana	13-17
16667813-3	1990	The abi1 and abi2 mutants showed reduced sensitivity to ABA for inhibition of seedling growth, induction of proline accumulation, and alterations in protein synthesis patterns during vegetative growth, but had wild type levels of storage reserves.	Proline	108-115	Protein phosphatase 2C family protein	Arabidopsis thaliana	13-17
34932819-8	2022	Our results reveal that ABA signaling regulates actin reorganization to maintain stomatal closure during drought stress and the feedback regulation of PYL1, ABI1 and ABI2 by the CKL2 kinase might fine-tune ABA signaling and affect plant ABA responses.	Abscisic Acid	206-209	Protein phosphatase 2C family protein	Arabidopsis thaliana	166-170
34932819-8	2022	Our results reveal that ABA signaling regulates actin reorganization to maintain stomatal closure during drought stress and the feedback regulation of PYL1, ABI1 and ABI2 by the CKL2 kinase might fine-tune ABA signaling and affect plant ABA responses.	Abscisic Acid	237-240	Protein phosphatase 2C family protein	Arabidopsis thaliana	166-170
34099554-5	2021	TMK1 inhibits the phosphatase activity of ABI2 by direct phosphorylation of threonine 321 (T321), a conserved phosphorylation site in ABI2 proteins, whose phosphorylation status is important for both auxin and ABA responses.	Indoleacetic Acids	200-205	Protein phosphatase 2C family protein	Arabidopsis thaliana	42-46
34099554-5	2021	TMK1 inhibits the phosphatase activity of ABI2 by direct phosphorylation of threonine 321 (T321), a conserved phosphorylation site in ABI2 proteins, whose phosphorylation status is important for both auxin and ABA responses.	Indoleacetic Acids	200-205	Protein phosphatase 2C family protein	Arabidopsis thaliana	134-138
34099554-5	2021	TMK1 inhibits the phosphatase activity of ABI2 by direct phosphorylation of threonine 321 (T321), a conserved phosphorylation site in ABI2 proteins, whose phosphorylation status is important for both auxin and ABA responses.	Threonine	76-85	Protein phosphatase 2C family protein	Arabidopsis thaliana	42-46
34099554-5	2021	TMK1 inhibits the phosphatase activity of ABI2 by direct phosphorylation of threonine 321 (T321), a conserved phosphorylation site in ABI2 proteins, whose phosphorylation status is important for both auxin and ABA responses.	Threonine	76-85	Protein phosphatase 2C family protein	Arabidopsis thaliana	134-138
34099554-5	2021	TMK1 inhibits the phosphatase activity of ABI2 by direct phosphorylation of threonine 321 (T321), a conserved phosphorylation site in ABI2 proteins, whose phosphorylation status is important for both auxin and ABA responses.	Abscisic Acid	210-213	Protein phosphatase 2C family protein	Arabidopsis thaliana	42-46
34099554-5	2021	TMK1 inhibits the phosphatase activity of ABI2 by direct phosphorylation of threonine 321 (T321), a conserved phosphorylation site in ABI2 proteins, whose phosphorylation status is important for both auxin and ABA responses.	Abscisic Acid	210-213	Protein phosphatase 2C family protein	Arabidopsis thaliana	134-138
31708935-6	2019	Bimolecular fluorescence complementation assays showed that AtPR5K2 physically interacted with the type 2C protein phosphatases ABA-insensitive 1 (ABI1) and ABI2 and the SNF1-related protein kinase 2 (SnRK2.6) proteins, all of which are involved in the initiation of abscisic acid (ABA) signaling; however, these interactions were inhibited by treatments of exogenous ABA.	Abscisic Acid	267-280	Protein phosphatase 2C family protein	Arabidopsis thaliana	157-161
32933749-4	2020	qRT-PCR assays indicated that NRT1.2 over-production in 7-days-old seedlings up-regulated the expression of ABA-responsive genes: ABI1, ABI2, ABI3, ABI4, ABI5, RAB18, RD29A, and RD29B and PHOSPHOLIPASE Dalpha1 (PLDalpha1).	Abscisic Acid	108-111	Protein phosphatase 2C family protein	Arabidopsis thaliana	136-140
35610574-7	2022	Furthermore, the expression levels of stress/ABA-responsive marker genes, including ABI1, ABI2, ABI4, ABI5 and RD29B, in the GsERF1 transgenic lines were affected by AlCl3 treatment, unlike those in the wild type.	Abscisic Acid	45-48	Protein phosphatase 2C family protein	Arabidopsis thaliana	90-94
35610574-7	2022	Furthermore, the expression levels of stress/ABA-responsive marker genes, including ABI1, ABI2, ABI4, ABI5 and RD29B, in the GsERF1 transgenic lines were affected by AlCl3 treatment, unlike those in the wild type.	Aluminum Chloride	166-171	Protein phosphatase 2C family protein	Arabidopsis thaliana	90-94
33487349-6	2021	Glucose treatment of the abscisic acid (ABA)-related mutants indicated that glucose-triggered upregulation of FMOGS-OX2 and FMOGS-OX4 was partially regulated by ABA through the key negative regulators ABI1 and ABI2, and the positive regulator SnRK2, but not via the transcription factor ABI5.	Glucose	0-7	Protein phosphatase 2C family protein	Arabidopsis thaliana	210-214
33487349-6	2021	Glucose treatment of the abscisic acid (ABA)-related mutants indicated that glucose-triggered upregulation of FMOGS-OX2 and FMOGS-OX4 was partially regulated by ABA through the key negative regulators ABI1 and ABI2, and the positive regulator SnRK2, but not via the transcription factor ABI5.	Abscisic Acid	25-38	Protein phosphatase 2C family protein	Arabidopsis thaliana	210-214
33487349-6	2021	Glucose treatment of the abscisic acid (ABA)-related mutants indicated that glucose-triggered upregulation of FMOGS-OX2 and FMOGS-OX4 was partially regulated by ABA through the key negative regulators ABI1 and ABI2, and the positive regulator SnRK2, but not via the transcription factor ABI5.	Abscisic Acid	40-43	Protein phosphatase 2C family protein	Arabidopsis thaliana	210-214
33487349-6	2021	Glucose treatment of the abscisic acid (ABA)-related mutants indicated that glucose-triggered upregulation of FMOGS-OX2 and FMOGS-OX4 was partially regulated by ABA through the key negative regulators ABI1 and ABI2, and the positive regulator SnRK2, but not via the transcription factor ABI5.	Glucose	76-83	Protein phosphatase 2C family protein	Arabidopsis thaliana	210-214
33487349-6	2021	Glucose treatment of the abscisic acid (ABA)-related mutants indicated that glucose-triggered upregulation of FMOGS-OX2 and FMOGS-OX4 was partially regulated by ABA through the key negative regulators ABI1 and ABI2, and the positive regulator SnRK2, but not via the transcription factor ABI5.	Abscisic Acid	161-164	Protein phosphatase 2C family protein	Arabidopsis thaliana	210-214
32619606-7	2020	ABT interacts with PYR1/PYL/RCAR and PP2C proteins, and interferes with the interaction between PYR1/PYL4 and ABI1/ABI2 and hampers the inhibition of ABI1/ABI2 by ABA-bound PYR1/PYL4, thereby terminates ABA signaling.	abt	0-3	Protein phosphatase 2C family protein	Arabidopsis thaliana	115-119
32619606-7	2020	ABT interacts with PYR1/PYL/RCAR and PP2C proteins, and interferes with the interaction between PYR1/PYL4 and ABI1/ABI2 and hampers the inhibition of ABI1/ABI2 by ABA-bound PYR1/PYL4, thereby terminates ABA signaling.	abt	0-3	Protein phosphatase 2C family protein	Arabidopsis thaliana	155-159
31708935-6	2019	Bimolecular fluorescence complementation assays showed that AtPR5K2 physically interacted with the type 2C protein phosphatases ABA-insensitive 1 (ABI1) and ABI2 and the SNF1-related protein kinase 2 (SnRK2.6) proteins, all of which are involved in the initiation of abscisic acid (ABA) signaling; however, these interactions were inhibited by treatments of exogenous ABA.	Abscisic Acid	128-131	Protein phosphatase 2C family protein	Arabidopsis thaliana	157-161
31708935-6	2019	Bimolecular fluorescence complementation assays showed that AtPR5K2 physically interacted with the type 2C protein phosphatases ABA-insensitive 1 (ABI1) and ABI2 and the SNF1-related protein kinase 2 (SnRK2.6) proteins, all of which are involved in the initiation of abscisic acid (ABA) signaling; however, these interactions were inhibited by treatments of exogenous ABA.	Abscisic Acid	282-285	Protein phosphatase 2C family protein	Arabidopsis thaliana	157-161
31708935-8	2019	Taken together, these results suggest that AtPR5K2 participates in ABA-dependent drought-stress signaling through the phosphorylation of ABI1 and ABI2.	Abscisic Acid	67-70	Protein phosphatase 2C family protein	Arabidopsis thaliana	146-150
28874521-2	2017	Key players of the ABA-signaling pathway are the ABA-binding receptors (RCAR/PYR1/PYL), which, together with a plant-specific subclade of protein phosphatase 2C (PP2C), form functional holoreceptors.	Abscisic Acid	19-22	Protein phosphatase 2C family protein	Arabidopsis thaliana	138-160
29490615-10	2018	Importantly, NCED3, ABI2, PP2CA, and major ABA-responsive marker genes, such as RD20 and RD29B, were down-regulated at both the transcript and protein levels in conjunction with lower contents of ABA and changes in the expression of a subset of LEA proteins in sahy9/apum23 mutants under salt stress.	Abscisic Acid	43-46	Protein phosphatase 2C family protein	Arabidopsis thaliana	20-24
29490615-10	2018	Importantly, NCED3, ABI2, PP2CA, and major ABA-responsive marker genes, such as RD20 and RD29B, were down-regulated at both the transcript and protein levels in conjunction with lower contents of ABA and changes in the expression of a subset of LEA proteins in sahy9/apum23 mutants under salt stress.	Abscisic Acid	196-199	Protein phosphatase 2C family protein	Arabidopsis thaliana	20-24
29335506-8	2018	Take ABI1 and ABI2, key negative regulators in ABA signal pathway, as examples, homologous alignment and a phylogenetic tree in various species showed that ABI1 and ABI2 are highly conserved among various species.	Abscisic Acid	47-50	Protein phosphatase 2C family protein	Arabidopsis thaliana	165-169
28174577-0	2017	A Novel RNA-Binding Protein Involves ABA Signaling by Post-transcriptionally Repressing ABI2.	alisol B 23-acetate	37-40	Protein phosphatase 2C family protein	Arabidopsis thaliana	88-92
28174577-10	2017	Together, it is suggested that SRP1 is involved in the ABA signaling by post-transcriptionally repressing ABI2 expression in Arabidopsis.	alisol B 23-acetate	55-58	Protein phosphatase 2C family protein	Arabidopsis thaliana	106-110
25917608-2	2015	Endogenous ABA levels are increased in response to a decrease in water availability in cells, and ABA sensing and signaling are thought to be mediated according to the current model established in Arabidopsis thaliana, which involves pyrabactin resistance 1 (PYR)/PYR1-like (PYL)/regulatory components of ABA receptor (RCAR), protein phosphatase 2C (PP2C) and sucrose non-fermenting-1 (SNF1)-related protein kinase 2 (SnRK2).	Abscisic Acid	98-101	Protein phosphatase 2C family protein	Arabidopsis thaliana	326-348
27566404-4	2016	In our previous work, we have shown that FER, through activation of the guanine nucleotide exchange factor 1 (GEF1)/4/10-Rho of Plant 11 (ROP11) pathway, enhances the activity of the phosphatase ABA Insensitive 2 (ABI2), a negative regulator of ABA signaling, thereby inhibiting ABA response.	Abscisic Acid	195-198	Protein phosphatase 2C family protein	Arabidopsis thaliana	214-218
27566404-4	2016	In our previous work, we have shown that FER, through activation of the guanine nucleotide exchange factor 1 (GEF1)/4/10-Rho of Plant 11 (ROP11) pathway, enhances the activity of the phosphatase ABA Insensitive 2 (ABI2), a negative regulator of ABA signaling, thereby inhibiting ABA response.	Abscisic Acid	245-248	Protein phosphatase 2C family protein	Arabidopsis thaliana	195-212
27566404-4	2016	In our previous work, we have shown that FER, through activation of the guanine nucleotide exchange factor 1 (GEF1)/4/10-Rho of Plant 11 (ROP11) pathway, enhances the activity of the phosphatase ABA Insensitive 2 (ABI2), a negative regulator of ABA signaling, thereby inhibiting ABA response.	Abscisic Acid	245-248	Protein phosphatase 2C family protein	Arabidopsis thaliana	214-218
27566404-8	2016	Several other ABI2-like phosphatases also function in this pathway, and ABA-dependent FER activation required PYRABACTIN RESISTANCE (PYR)/PYR1-LIKE (PYL)/REGULATORY COMPONENTS OF ABA RECEPTORS (RCAR)-A-type protein phosphatase type 2C (PP2CA) modules.	Abscisic Acid	72-75	Protein phosphatase 2C family protein	Arabidopsis thaliana	14-18
27566404-8	2016	Several other ABI2-like phosphatases also function in this pathway, and ABA-dependent FER activation required PYRABACTIN RESISTANCE (PYR)/PYR1-LIKE (PYL)/REGULATORY COMPONENTS OF ABA RECEPTORS (RCAR)-A-type protein phosphatase type 2C (PP2CA) modules.	pyrabactin	110-120	Protein phosphatase 2C family protein	Arabidopsis thaliana	14-18
27406784-6	2016	We further showed that WRKY18, WRKY40 and WRKY60 transcription factors repress the expression of CRK5, and that CRK5 likely functions upstream of ABI2 in ABA signaling.	Abscisic Acid	154-157	Protein phosphatase 2C family protein	Arabidopsis thaliana	146-150
26491145-3	2015	Here, we report that a rice ortholog of AtABI1 and AtABI2, named OsABI-LIKE2 (OsABIL2), plays a negative role in rice ABA signaling.	alisol B 23-acetate	118-121	Protein phosphatase 2C family protein	Arabidopsis thaliana	51-57
27566404-0	2016	FERONIA interacts with ABI2-type phosphatases to facilitate signaling cross-talk between abscisic acid and RALF peptide in Arabidopsis.	Abscisic Acid	89-102	Protein phosphatase 2C family protein	Arabidopsis thaliana	23-27
26974851-4	2016	We proposed that ORA47 acts as a connection between ABA INSENSITIVE1 (ABI1) and ABI2 and mediates an ABI1-ORA47-ABI2 positive feedback loop.	Abscisic Acid	52-55	Protein phosphatase 2C family protein	Arabidopsis thaliana	80-84
26974851-4	2016	We proposed that ORA47 acts as a connection between ABA INSENSITIVE1 (ABI1) and ABI2 and mediates an ABI1-ORA47-ABI2 positive feedback loop.	Abscisic Acid	52-55	Protein phosphatase 2C family protein	Arabidopsis thaliana	112-116
23658427-8	2013	CIPK26 was found to interact with the ABA signalling components ABI1, ABI2, and ABI5.	Abscisic Acid	38-41	Protein phosphatase 2C family protein	Arabidopsis thaliana	70-74
25266633-8	2014	However, the Arabidopsis clade-A PROTEIN PHOSPHATASE2C mutant abscisic acid-insensitive1 (abi1-1) does not close the stomata when epidermal strips were treated with H2S, suggesting that H2S required a functional ABI1.	Abscisic Acid	62-75	Protein phosphatase 2C family protein	Arabidopsis thaliana	33-54
25266633-8	2014	However, the Arabidopsis clade-A PROTEIN PHOSPHATASE2C mutant abscisic acid-insensitive1 (abi1-1) does not close the stomata when epidermal strips were treated with H2S, suggesting that H2S required a functional ABI1.	Hydrogen Sulfide	186-189	Protein phosphatase 2C family protein	Arabidopsis thaliana	33-54
24808098-7	2014	Analysis of genetic interactions with phytochrome and abi mutants indicates that ZFP3 enhances red light signaling by photoreceptors other than phytochrome A and additively increases ABA insensitivity conferred by the abi2, abi4, and abi5 mutations.	Abscisic Acid	183-186	Protein phosphatase 2C family protein	Arabidopsis thaliana	218-222
25943353-0	2015	Nitrate sensing and uptake in Arabidopsis are enhanced by ABI2, a phosphatase inactivated by the stress hormone abscisic acid.	Nitrates	0-7	Protein phosphatase 2C family protein	Arabidopsis thaliana	58-62
25943353-0	2015	Nitrate sensing and uptake in Arabidopsis are enhanced by ABI2, a phosphatase inactivated by the stress hormone abscisic acid.	Abscisic Acid	112-125	Protein phosphatase 2C family protein	Arabidopsis thaliana	58-62
25943353-5	2015	We identified two additional components that regulate nitrate transport, sensing, and signaling: the calcium sensor CBL1 and protein phosphatase 2C family member ABI2, which is inhibited by the stress-response hormone abscisic acid.	Nitrates	54-61	Protein phosphatase 2C family protein	Arabidopsis thaliana	162-166
25943353-5	2015	We identified two additional components that regulate nitrate transport, sensing, and signaling: the calcium sensor CBL1 and protein phosphatase 2C family member ABI2, which is inhibited by the stress-response hormone abscisic acid.	Calcium	101-108	Protein phosphatase 2C family protein	Arabidopsis thaliana	162-166
25943353-5	2015	We identified two additional components that regulate nitrate transport, sensing, and signaling: the calcium sensor CBL1 and protein phosphatase 2C family member ABI2, which is inhibited by the stress-response hormone abscisic acid.	Abscisic Acid	218-231	Protein phosphatase 2C family protein	Arabidopsis thaliana	162-166
25943353-8	2015	These findings suggest that ABI2 may functionally link stress-regulated control of growth and nitrate uptake and utilization, which are energy-expensive processes.	Nitrates	94-101	Protein phosphatase 2C family protein	Arabidopsis thaliana	28-32
25758810-3	2015	We previously developed 3"-hexylsulfanyl-ABA (AS6), whose S-hexyl chain blocks protein phosphatase 2C (PP2C) binding by steric hindrance.	3"-hexylsulfanyl-aba	24-44	Protein phosphatase 2C family protein	Arabidopsis thaliana	79-101
25758810-3	2015	We previously developed 3"-hexylsulfanyl-ABA (AS6), whose S-hexyl chain blocks protein phosphatase 2C (PP2C) binding by steric hindrance.	4-O-carboxymethylascochlorin	46-49	Protein phosphatase 2C family protein	Arabidopsis thaliana	79-101
22908257-0	2012	FERONIA receptor kinase pathway suppresses abscisic acid signaling in Arabidopsis by activating ABI2 phosphatase.	Abscisic Acid	43-56	Protein phosphatase 2C family protein	Arabidopsis thaliana	96-100
23483290-9	2013	Moreover, the transcript levels of ABA biosynthesis (ABA1, ABA2), ABA signaling (ABI1, ABI2) and stress-responsive genes, including RD29A and CBF3, were generally higher in GmNFYA3 plants than in wild-type controls under normal conditions.	Abscisic Acid	35-38	Protein phosphatase 2C family protein	Arabidopsis thaliana	87-91
23660402-3	2013	Following NaCl treatment, the expressions of ABI1, ABI2 and AtPP2CA, which encode type 2C serine/threonine protein phosphatases (PP2Cs) that act as negative regulators in abscisic acid (ABA) signaling, were suppressed in AtMYB20-OX but induced in AtMYB20-SRDX.	Sodium Chloride	10-14	Protein phosphatase 2C family protein	Arabidopsis thaliana	51-55
23660402-3	2013	Following NaCl treatment, the expressions of ABI1, ABI2 and AtPP2CA, which encode type 2C serine/threonine protein phosphatases (PP2Cs) that act as negative regulators in abscisic acid (ABA) signaling, were suppressed in AtMYB20-OX but induced in AtMYB20-SRDX.	Abscisic Acid	171-184	Protein phosphatase 2C family protein	Arabidopsis thaliana	51-55
23660402-3	2013	Following NaCl treatment, the expressions of ABI1, ABI2 and AtPP2CA, which encode type 2C serine/threonine protein phosphatases (PP2Cs) that act as negative regulators in abscisic acid (ABA) signaling, were suppressed in AtMYB20-OX but induced in AtMYB20-SRDX.	Abscisic Acid	186-189	Protein phosphatase 2C family protein	Arabidopsis thaliana	51-55
23606412-6	2013	Moreover, microarray and qRT-PCR assays showed that GsWRKY20 mediated ABA signalling by promoting the expression of negative regulators of ABA signalling, such as AtWRKY40, ABI1, and ABI2, while repressing the expression of the positive regulators of ABA, for example ABI5, ABI4, and ABF4.	Abscisic Acid	70-73	Protein phosphatase 2C family protein	Arabidopsis thaliana	183-187
23606412-6	2013	Moreover, microarray and qRT-PCR assays showed that GsWRKY20 mediated ABA signalling by promoting the expression of negative regulators of ABA signalling, such as AtWRKY40, ABI1, and ABI2, while repressing the expression of the positive regulators of ABA, for example ABI5, ABI4, and ABF4.	Abscisic Acid	139-142	Protein phosphatase 2C family protein	Arabidopsis thaliana	183-187
23606412-6	2013	Moreover, microarray and qRT-PCR assays showed that GsWRKY20 mediated ABA signalling by promoting the expression of negative regulators of ABA signalling, such as AtWRKY40, ABI1, and ABI2, while repressing the expression of the positive regulators of ABA, for example ABI5, ABI4, and ABF4.	Abscisic Acid	139-142	Protein phosphatase 2C family protein	Arabidopsis thaliana	183-187
23483290-9	2013	Moreover, the transcript levels of ABA biosynthesis (ABA1, ABA2), ABA signaling (ABI1, ABI2) and stress-responsive genes, including RD29A and CBF3, were generally higher in GmNFYA3 plants than in wild-type controls under normal conditions.	Abscisic Acid	53-56	Protein phosphatase 2C family protein	Arabidopsis thaliana	87-91
22908257-3	2012	Here, we report a cross-talk mechanism that enables a receptor-like kinase, FERONIA (FER), a positive regulator of auxin-promoted growth, to suppress the abscisic acid (ABA) response through activation of ABI2, a negative regulator of ABA signaling.	Abscisic Acid	154-167	Protein phosphatase 2C family protein	Arabidopsis thaliana	205-209
22908257-3	2012	Here, we report a cross-talk mechanism that enables a receptor-like kinase, FERONIA (FER), a positive regulator of auxin-promoted growth, to suppress the abscisic acid (ABA) response through activation of ABI2, a negative regulator of ABA signaling.	Abscisic Acid	169-172	Protein phosphatase 2C family protein	Arabidopsis thaliana	205-209
22908257-3	2012	Here, we report a cross-talk mechanism that enables a receptor-like kinase, FERONIA (FER), a positive regulator of auxin-promoted growth, to suppress the abscisic acid (ABA) response through activation of ABI2, a negative regulator of ABA signaling.	Abscisic Acid	235-238	Protein phosphatase 2C family protein	Arabidopsis thaliana	205-209
22908257-6	2012	In search of the target for the FER pathway, we found that the ROP11/ARAC10 protein physically interacted with the ABI2 phosphatase and enhanced its activity, thereby linking the FER pathway with the inhibition of ABA signaling.	Abscisic Acid	214-217	Protein phosphatase 2C family protein	Arabidopsis thaliana	115-119
22121246-0	2012	Molecular and physiological characterization of the Arabidopsis thaliana Oxidation-related Zinc Finger 2, a plasma membrane protein involved in ABA and salt stress response through the ABI2-mediated signaling pathway.	alisol B 23-acetate	144-147	Protein phosphatase 2C family protein	Arabidopsis thaliana	185-189
22730405-7	2012	Our study identifies a critical component in ABA and H2O2 signaling that is involved in stomatal movement and resolves a long-standing mystery about the differential functions of ABI1 and ABI2 in this process.	Abscisic Acid	45-48	Protein phosphatase 2C family protein	Arabidopsis thaliana	188-192
22730405-7	2012	Our study identifies a critical component in ABA and H2O2 signaling that is involved in stomatal movement and resolves a long-standing mystery about the differential functions of ABI1 and ABI2 in this process.	Hydrogen Peroxide	53-57	Protein phosphatase 2C family protein	Arabidopsis thaliana	188-192
22705253-8	2012	Negative ABA signaling regulators, such as ABI1 and ABI2, were up-regulated in over-expression lines, while positive ABA signaling regulators, such as ABF4, ABI5, GTG1, GTG2, PYR1/RCAR11, PYL2/RCAR13, SnRK2.2 and SnRK2.3, were down-regulated, in comparison to wild type plants.	alisol B 23-acetate	9-12	Protein phosphatase 2C family protein	Arabidopsis thaliana	52-56
22368268-8	2012	The expression of ABA-responsive genes, ABI1 and ABI2, was increased in hda6, hd2c, and hda6/hd2c-1 double mutant plants, which was associated with increased histone H3K9K14 acetylation and decreased histone H3K9 dimethylation.	alisol B 23-acetate	18-21	Protein phosphatase 2C family protein	Arabidopsis thaliana	49-53
22404835-0	2012	Functional roles of the protein phosphatase 2C, AtAIP1, in abscisic acid signaling and sugar tolerance in Arabidopsis.	Abscisic Acid	59-72	Protein phosphatase 2C family protein	Arabidopsis thaliana	24-46
22404835-0	2012	Functional roles of the protein phosphatase 2C, AtAIP1, in abscisic acid signaling and sugar tolerance in Arabidopsis.	Sugars	87-92	Protein phosphatase 2C family protein	Arabidopsis thaliana	24-46
22404835-3	2012	ABA is linked to ABA receptors and protein phosphatase 2C (PP2C) members.	Abscisic Acid	0-3	Protein phosphatase 2C family protein	Arabidopsis thaliana	35-57
22121246-9	2012	Interestingly, in the presence of ABA and salt stress, the transcript level of ABA insensitive 2 (ABI2), but not that of ABI1, in AtOZF2-overexpressing plants was lower than that in the wild type, whereas the expression of ABI2 in atozf2 was significantly enhanced.	alisol B 23-acetate	34-37	Protein phosphatase 2C family protein	Arabidopsis thaliana	79-96
22121246-9	2012	Interestingly, in the presence of ABA and salt stress, the transcript level of ABA insensitive 2 (ABI2), but not that of ABI1, in AtOZF2-overexpressing plants was lower than that in the wild type, whereas the expression of ABI2 in atozf2 was significantly enhanced.	alisol B 23-acetate	34-37	Protein phosphatase 2C family protein	Arabidopsis thaliana	98-102
22121246-9	2012	Interestingly, in the presence of ABA and salt stress, the transcript level of ABA insensitive 2 (ABI2), but not that of ABI1, in AtOZF2-overexpressing plants was lower than that in the wild type, whereas the expression of ABI2 in atozf2 was significantly enhanced.	Salts	42-46	Protein phosphatase 2C family protein	Arabidopsis thaliana	79-96
22121246-9	2012	Interestingly, in the presence of ABA and salt stress, the transcript level of ABA insensitive 2 (ABI2), but not that of ABI1, in AtOZF2-overexpressing plants was lower than that in the wild type, whereas the expression of ABI2 in atozf2 was significantly enhanced.	Salts	42-46	Protein phosphatase 2C family protein	Arabidopsis thaliana	98-102
22121246-10	2012	Thus, AtOZF2 is involved in the ABA and salt stress response through the ABI2-mediated signaling pathway.	alisol B 23-acetate	32-35	Protein phosphatase 2C family protein	Arabidopsis thaliana	73-77
22128331-10	2011	Endogenous ABA decreased along with positive ABA signaling as expression of ABI2, ABI4, and ABA catabolism (CYP707A2) and GA synthesis (GA3ox1) genes increased.	Abscisic Acid	11-14	Protein phosphatase 2C family protein	Arabidopsis thaliana	76-80
22128331-10	2011	Endogenous ABA decreased along with positive ABA signaling as expression of ABI2, ABI4, and ABA catabolism (CYP707A2) and GA synthesis (GA3ox1) genes increased.	Abscisic Acid	45-48	Protein phosphatase 2C family protein	Arabidopsis thaliana	76-80
22128331-10	2011	Endogenous ABA decreased along with positive ABA signaling as expression of ABI2, ABI4, and ABA catabolism (CYP707A2) and GA synthesis (GA3ox1) genes increased.	Abscisic Acid	45-48	Protein phosphatase 2C family protein	Arabidopsis thaliana	76-80
21976481-7	2011	The ABA conjugate and precursors showed negligible activity as a regulatory ligand of the ABI2/RCAR receptor complexes.	Abscisic Acid	4-7	Protein phosphatase 2C family protein	Arabidopsis thaliana	90-94
21885535-0	2011	Identification of an important site for function of the type 2C protein phosphatase ABI2 in abscisic acid signalling in Arabidopsis.	Abscisic Acid	92-105	Protein phosphatase 2C family protein	Arabidopsis thaliana	84-88
21885535-1	2011	It is known that the clade A protein phosphatase 2Cs (PP2Cs), including ABI1 and ABI2 and other PP2C members, are key players that function directly downstream of the PYR/PYL/RCAR abscisic acid (ABA) receptors.	Abscisic Acid	180-193	Protein phosphatase 2C family protein	Arabidopsis thaliana	81-85
21885535-1	2011	It is known that the clade A protein phosphatase 2Cs (PP2Cs), including ABI1 and ABI2 and other PP2C members, are key players that function directly downstream of the PYR/PYL/RCAR abscisic acid (ABA) receptors.	Abscisic Acid	195-198	Protein phosphatase 2C family protein	Arabidopsis thaliana	81-85
21885535-2	2011	Here, identification of a crucial site for function of ABI2 protein phosphatase in ABA signalling is reported.	Abscisic Acid	83-86	Protein phosphatase 2C family protein	Arabidopsis thaliana	55-59
21885535-4	2011	Further, genetic evidence was provided to demonstrate that this CPL is required for the function of ABI2 to mediate ABA signalling.	Abscisic Acid	116-119	Protein phosphatase 2C family protein	Arabidopsis thaliana	100-104
21885535-5	2011	These data reveal that this CPL is an important site necessary for both the phosphatase activity of ABI2 and the functional interaction between ABI2 and PYL5/9 ABA receptors, providing new information to understand primary events of ABA signal transduction.	Abscisic Acid	160-163	Protein phosphatase 2C family protein	Arabidopsis thaliana	100-104
21885535-5	2011	These data reveal that this CPL is an important site necessary for both the phosphatase activity of ABI2 and the functional interaction between ABI2 and PYL5/9 ABA receptors, providing new information to understand primary events of ABA signal transduction.	Abscisic Acid	160-163	Protein phosphatase 2C family protein	Arabidopsis thaliana	144-148
21525137-8	2011	Expression levels of abscisic acid-related genes ABI1, ABI2, RAB18, PP2CA, and SOT12 were substantially reduced in salt-treated npc4 plants.	Abscisic Acid	21-34	Protein phosphatase 2C family protein	Arabidopsis thaliana	55-59
21821598-7	2011	In this study, transcriptome analysis reveals that the M6PR transgene activated the downstream abscisic acid (ABA) pathway by up-regulation of ABA receptor genes (PYL4, PYL5, and PYL6) and down-regulation of protein phosphatase 2C genes (ABI1 and ABI2).	Abscisic Acid	95-108	Protein phosphatase 2C family protein	Arabidopsis thaliana	247-251
21821598-7	2011	In this study, transcriptome analysis reveals that the M6PR transgene activated the downstream abscisic acid (ABA) pathway by up-regulation of ABA receptor genes (PYL4, PYL5, and PYL6) and down-regulation of protein phosphatase 2C genes (ABI1 and ABI2).	Abscisic Acid	110-113	Protein phosphatase 2C family protein	Arabidopsis thaliana	247-251
21525137-8	2011	Expression levels of abscisic acid-related genes ABI1, ABI2, RAB18, PP2CA, and SOT12 were substantially reduced in salt-treated npc4 plants.	Salts	115-119	Protein phosphatase 2C family protein	Arabidopsis thaliana	55-59
21478367-6	2011	Genetic analyses support that, like RHA2a, the RHA2b action in ABA signaling is downstream of a protein phosphatase 2C, ABA-INSENSITIVE2 (ABI2), and in parallel with that of the ABI transcription factors ABI3/4/5.	Abscisic Acid	63-66	Protein phosphatase 2C family protein	Arabidopsis thaliana	120-136
21478367-6	2011	Genetic analyses support that, like RHA2a, the RHA2b action in ABA signaling is downstream of a protein phosphatase 2C, ABA-INSENSITIVE2 (ABI2), and in parallel with that of the ABI transcription factors ABI3/4/5.	Abscisic Acid	63-66	Protein phosphatase 2C family protein	Arabidopsis thaliana	138-142
20930557-4	2010	Compared with wild-type plants, the expression of ABA responsive genes, ABI1, ABI2, KAT1, KAT2, and RD29B, was decreased in hda19-1 plants when treated with ABA.	alisol B 23-acetate	50-53	Protein phosphatase 2C family protein	Arabidopsis thaliana	78-82
20930557-4	2010	Compared with wild-type plants, the expression of ABA responsive genes, ABI1, ABI2, KAT1, KAT2, and RD29B, was decreased in hda19-1 plants when treated with ABA.	alisol B 23-acetate	157-160	Protein phosphatase 2C family protein	Arabidopsis thaliana	78-82
20519338-6	2010	Compared with wild-type plants, the expression of the ABA and abiotic stress-responsive genes, ABI1, ABI2, KAT1, KAT2, DREB2A, RD29A, and RD29B, was decreased in axe1-5 and HDA6 RNA-interfering plants when treated with ABA or salt stress.	alisol B 23-acetate	54-57	Protein phosphatase 2C family protein	Arabidopsis thaliana	101-105
20803085-5	2010	We detected that salt-induced expressions of a transcriptional repressor gene, AtERF4, and some Ser/Thr protein phosphatase2C genes, ABI1, ABI2 and AtPP2CA, were suppressed in BrERF4-overexpressing Arabidopsis plants.	Salts	17-21	Protein phosphatase 2C family protein	Arabidopsis thaliana	139-143
20519338-6	2010	Compared with wild-type plants, the expression of the ABA and abiotic stress-responsive genes, ABI1, ABI2, KAT1, KAT2, DREB2A, RD29A, and RD29B, was decreased in axe1-5 and HDA6 RNA-interfering plants when treated with ABA or salt stress.	alisol B 23-acetate	219-222	Protein phosphatase 2C family protein	Arabidopsis thaliana	101-105
20519338-6	2010	Compared with wild-type plants, the expression of the ABA and abiotic stress-responsive genes, ABI1, ABI2, KAT1, KAT2, DREB2A, RD29A, and RD29B, was decreased in axe1-5 and HDA6 RNA-interfering plants when treated with ABA or salt stress.	Salts	226-230	Protein phosphatase 2C family protein	Arabidopsis thaliana	101-105
19407143-2	2009	Key players in ABA signal transduction include the type 2C protein phosphatases (PP2Cs) ABI1 and ABI2, which act by negatively regulating ABA responses.	Abscisic Acid	15-18	Protein phosphatase 2C family protein	Arabidopsis thaliana	97-101
20488890-9	2010	In addition, the response of ABA-inducible genes such as ABI1, ABI2, RD29A, and Erd10 was reduced in the mutant plants.	Abscisic Acid	29-32	Protein phosphatase 2C family protein	Arabidopsis thaliana	63-67
19624469-8	2009	PYL5 and other members of its protein family inhibited HAB1, ABI1 and ABI2 phosphatase activity in an ABA-dependent manner.	Abscisic Acid	102-105	Protein phosphatase 2C family protein	Arabidopsis thaliana	70-74
19769575-7	2010	RCAR3 was identified in a screen for interactors of the PP2Cs ABI1 and ABI2, which are key regulators of ABA responses.	Abscisic Acid	105-108	Protein phosphatase 2C family protein	Arabidopsis thaliana	71-75
19769575-10	2010	In addition, regulation of the protein phosphatase activity by RCAR1 and RCAR3 was more sensitive to ABA for ABI1 than for ABI2.	Abscisic Acid	101-104	Protein phosphatase 2C family protein	Arabidopsis thaliana	123-127
19855047-6	2009	Furthermore, HAB1 and the related PP2Cs ABI1 and ABI2 interact with OST1 in vivo, and mutations in the corresponding genes strongly affect OST1 activation by ABA.	Abscisic Acid	158-161	Protein phosphatase 2C family protein	Arabidopsis thaliana	49-53
19407143-2	2009	Key players in ABA signal transduction include the type 2C protein phosphatases (PP2Cs) ABI1 and ABI2, which act by negatively regulating ABA responses.	Abscisic Acid	138-141	Protein phosphatase 2C family protein	Arabidopsis thaliana	97-101
19407143-5	2009	RCAR1 was shown to bind ABA, to mediate ABA-dependent inactivation of ABI1 or ABI2 in vitro, and to antagonize PP2C action in planta.	Abscisic Acid	40-43	Protein phosphatase 2C family protein	Arabidopsis thaliana	78-82
19407143-6	2009	Other RCARs also mediated ABA-dependent regulation of ABI1 and ABI2, consistent with a combinatorial assembly of receptor complexes.	Abscisic Acid	26-29	Protein phosphatase 2C family protein	Arabidopsis thaliana	63-67
18278579-12	2008	Mutant analysis further identified the ABA response pathway genes ENHANCED RESPONSE TO ABA1 (ERA1) and ABI2 as intermediates in glucose signalling.	Abscisic Acid	39-42	Protein phosphatase 2C family protein	Arabidopsis thaliana	103-107
18278579-12	2008	Mutant analysis further identified the ABA response pathway genes ENHANCED RESPONSE TO ABA1 (ERA1) and ABI2 as intermediates in glucose signalling.	Glucose	128-135	Protein phosphatase 2C family protein	Arabidopsis thaliana	103-107
16365038-1	2006	ABI1 and ABI2 encode PP2C-type protein phosphatases and are thought to negatively regulate many aspects of abscisic acid (ABA) signaling, including stomatal closure in Arabidopsis.	Abscisic Acid	107-120	Protein phosphatase 2C family protein	Arabidopsis thaliana	9-13
16998070-7	2006	The reduced form of ABI2 was converted to the oxidized form by the addition of oxidized ATGPX3 in vitro, which might mediate ABA and oxidative signaling.	Abscisic Acid	125-128	Protein phosphatase 2C family protein	Arabidopsis thaliana	20-24
18162593-7	2008	Microarray analysis and northern blots revealed that salt-induced activation of the genes that encode a group of serine/threonine protein phosphatases 2C (PP2Cs), such as ABI1, ABI2, AtPP2CA, HAB1, and HAB2, was diminished in transgenic plants overexpressing AtMYB44.	Salts	53-57	Protein phosphatase 2C family protein	Arabidopsis thaliana	177-181
17766402-7	2007	Overexpression of the Arabidopsis NAE degrading enzyme fatty acid amide hydrolase resulted in seedlings that were hypersensitive to ABA, whereas the ABA-insensitive mutants, abi1-1, abi2-1, and abi3-1, exhibited reduced sensitivity to NAE.	N-acylethanolamines	34-37	Protein phosphatase 2C family protein	Arabidopsis thaliana	182-186
16571665-4	2006	ABA induces fibrillin accumulation, and the ABA response regulators ABI1 and ABI2 regulate fibrillin expression.	Abscisic Acid	44-47	Protein phosphatase 2C family protein	Arabidopsis thaliana	77-81
16571665-9	2006	Thus, ABI1 and ABI2 seem to control fibrillin expression that is involved in mediating ABA-induced photoprotection.	Abscisic Acid	87-90	Protein phosphatase 2C family protein	Arabidopsis thaliana	15-19
16365038-1	2006	ABI1 and ABI2 encode PP2C-type protein phosphatases and are thought to negatively regulate many aspects of abscisic acid (ABA) signaling, including stomatal closure in Arabidopsis.	Abscisic Acid	122-125	Protein phosphatase 2C family protein	Arabidopsis thaliana	9-13
16339784-6	2006	Quantification of low water potential-induced ABA and Pro accumulation in five ABA-insensitive mutants, abi1-1, abi2-1, abi3, abi4, and abi5, revealed that abi4 had increased Pro accumulation at low water potential, but a reduced response to exogenous ABA.	Water	22-27	Protein phosphatase 2C family protein	Arabidopsis thaliana	112-116
11208021-0	2001	The ABI1 and ABI2 protein phosphatases 2C act in a negative feedback regulatory loop of the abscisic acid signalling pathway.	Abscisic Acid	92-105	Protein phosphatase 2C family protein	Arabidopsis thaliana	13-17
16021341-10	2005	The expression of the ABA responsive genes, ABI2, rd29B and rab18, was decreased in the 35S:AtERF4-GFP transgenic plants.	Abscisic Acid	22-25	Protein phosphatase 2C family protein	Arabidopsis thaliana	44-48
15599761-0	2005	The ABI2-dependent abscisic acid signalling controls HrpN-induced drought tolerance in Arabidopsis.	Abscisic Acid	19-32	Protein phosphatase 2C family protein	Arabidopsis thaliana	4-8
15599761-9	2005	Thus, an ABI2-dependent ABA signalling pathway is responsible for the induction of DT but does not affect pathogen defence under the circumstances of this study.	Abscisic Acid	24-27	Protein phosphatase 2C family protein	Arabidopsis thaliana	9-13
15599761-9	2005	Thus, an ABI2-dependent ABA signalling pathway is responsible for the induction of DT but does not affect pathogen defence under the circumstances of this study.	Thymidine	83-85	Protein phosphatase 2C family protein	Arabidopsis thaliana	9-13
12662310-3	2003	Based on germination in the presence of exogenous ABA, the ABI1 and ABI2 phosphatases act at or upstream of the ERA1 farnesyl transferase and the ABI3 and ABI5 transcription factors act at or downstream of ERA1.	Abscisic Acid	50-53	Protein phosphatase 2C family protein	Arabidopsis thaliana	68-72
16339784-9	2006	It was also observed that abi1-1 and abi2-1 had increased ABA accumulation.	Abscisic Acid	58-61	Protein phosphatase 2C family protein	Arabidopsis thaliana	37-41
16339800-0	2006	ABA-hypersensitive germination3 encodes a protein phosphatase 2C (AtPP2CA) that strongly regulates abscisic acid signaling during germination among Arabidopsis protein phosphatase 2Cs.	Abscisic Acid	99-112	Protein phosphatase 2C family protein	Arabidopsis thaliana	42-64
15923322-6	2005	Abscisic acid (ABA) signaling mutants (abi1 and abi2) and the UV-sensitive mutant, uvh6, showed the strongest defects in acquired thermotolerance of root growth and seedling survival.	Abscisic Acid	0-13	Protein phosphatase 2C family protein	Arabidopsis thaliana	48-52
15923322-6	2005	Abscisic acid (ABA) signaling mutants (abi1 and abi2) and the UV-sensitive mutant, uvh6, showed the strongest defects in acquired thermotolerance of root growth and seedling survival.	Abscisic Acid	15-18	Protein phosphatase 2C family protein	Arabidopsis thaliana	48-52
12970489-8	2003	Finally, the Glc-mediated regulation of ABI4 and ABI5 is affected in mutants displaying Glc-insensitive phenotypes such as gins, abas, abi4, abi5, and ctr1 but not in abi1-1, abi2-1, and abi3-1, which do not show a Glc-insensitive phenotype.	Glucose	13-16	Protein phosphatase 2C family protein	Arabidopsis thaliana	175-179
12857845-7	2003	ABA induction of ABI1 and ABI2, negative regulators of ABA signaling, was strongly inhibited by VP1, revealing a second pathway of feed-forward regulation.	Abscisic Acid	0-3	Protein phosphatase 2C family protein	Arabidopsis thaliana	26-30
12857845-7	2003	ABA induction of ABI1 and ABI2, negative regulators of ABA signaling, was strongly inhibited by VP1, revealing a second pathway of feed-forward regulation.	Abscisic Acid	55-58	Protein phosphatase 2C family protein	Arabidopsis thaliana	26-30
12514244-2	2002	Two protein phosphatase genes, ABI1 and ABI2, are known to regulate these signaling pathways in Arabidopsis: The identity of ABA-activated protein kinases required for the ABA signaling, however, remains to be elucidated.	alisol B 23-acetate	125-128	Protein phosphatase 2C family protein	Arabidopsis thaliana	40-44
12034902-4	2002	By screening a two-hybrid cDNA library, we isolated a protein phosphatase 2C (AtPP2CA) involved in abscisic acid signaling as a putative partner of AKT2.	Abscisic Acid	99-112	Protein phosphatase 2C family protein	Arabidopsis thaliana	54-76
11882947-0	2002	The sensitivity of ABI2 to hydrogen peroxide links the abscisic acid-response regulator to redox signalling.	Hydrogen Peroxide	27-44	Protein phosphatase 2C family protein	Arabidopsis thaliana	19-23
11882947-0	2002	The sensitivity of ABI2 to hydrogen peroxide links the abscisic acid-response regulator to redox signalling.	Abscisic Acid	55-68	Protein phosphatase 2C family protein	Arabidopsis thaliana	19-23
11882947-4	2002	Analysis of the enzymatic properties of ABI2 revealed high sensitivities towards protons and unsaturated fatty acids.	Fatty Acids, Unsaturated	93-116	Protein phosphatase 2C family protein	Arabidopsis thaliana	40-44
11882947-5	2002	Furthermore, the protein phosphatase activity of ABI2 is very sensitive to H2O2, which has recently emerged as a secondary messenger of ABA signalling.	Hydrogen Peroxide	75-79	Protein phosphatase 2C family protein	Arabidopsis thaliana	49-53
11882947-5	2002	Furthermore, the protein phosphatase activity of ABI2 is very sensitive to H2O2, which has recently emerged as a secondary messenger of ABA signalling.	Abscisic Acid	136-139	Protein phosphatase 2C family protein	Arabidopsis thaliana	49-53
11882947-6	2002	Upon H2O2 challenge, ABI2 is rapidly inactivated with an IC50 value of 50 microM in the presence of reduced glutathione.	Hydrogen Peroxide	5-9	Protein phosphatase 2C family protein	Arabidopsis thaliana	21-25
11882947-6	2002	Upon H2O2 challenge, ABI2 is rapidly inactivated with an IC50 value of 50 microM in the presence of reduced glutathione.	Glutathione	108-119	Protein phosphatase 2C family protein	Arabidopsis thaliana	21-25
11882947-7	2002	Inhibitor studies with phenylarsine oxide and manipulation of the redox status of ABI2 in vitro indicate that oxidation of critical cysteine residue(s) is responsible for inactivation.	Cysteine	132-140	Protein phosphatase 2C family protein	Arabidopsis thaliana	82-86
11882947-8	2002	The levels of the major cellular thiol compounds cysteine and glutathione in leaves and seedlings of A. thaliana are compatible with a physiological role of H2O2 in regulating ABI2 activity.	Sulfhydryl Compounds	33-38	Protein phosphatase 2C family protein	Arabidopsis thaliana	176-180
11882947-8	2002	The levels of the major cellular thiol compounds cysteine and glutathione in leaves and seedlings of A. thaliana are compatible with a physiological role of H2O2 in regulating ABI2 activity.	Cysteine	49-57	Protein phosphatase 2C family protein	Arabidopsis thaliana	176-180
11882947-8	2002	The levels of the major cellular thiol compounds cysteine and glutathione in leaves and seedlings of A. thaliana are compatible with a physiological role of H2O2 in regulating ABI2 activity.	Hydrogen Peroxide	157-161	Protein phosphatase 2C family protein	Arabidopsis thaliana	176-180
11882947-9	2002	ABI2 is considered to exert negative regulation on ABA action.	Abscisic Acid	51-54	Protein phosphatase 2C family protein	Arabidopsis thaliana	0-4
11208021-2	2001	These genes have been originally identified by the dominant mutations abi1--1 and abi2--1, which reduce the plant"s responsiveness to the hormone abscisic acid (ABA).	Abscisic Acid	146-159	Protein phosphatase 2C family protein	Arabidopsis thaliana	82-86
11208021-2	2001	These genes have been originally identified by the dominant mutations abi1--1 and abi2--1, which reduce the plant"s responsiveness to the hormone abscisic acid (ABA).	Abscisic Acid	161-164	Protein phosphatase 2C family protein	Arabidopsis thaliana	82-86
11208021-6	2001	Abi2--1R1 plants displayed a wild-type ABA sensitivity.	Abscisic Acid	39-42	Protein phosphatase 2C family protein	Arabidopsis thaliana	0-4
11208021-7	2001	However, doubly mutant plants combining the abi2--1R1 allele and a loss-of-function allele at the ABI1 locus were more responsive to ABA than each of the parental single mutants.	Abscisic Acid	133-136	Protein phosphatase 2C family protein	Arabidopsis thaliana	44-48
11208021-8	2001	These data indicate that the wild-type ABI2 phosphatase is a negative regulator of ABA signalling, and that the ABI1 and ABI2 phosphatases have overlapping roles in controlling ABA action.	Abscisic Acid	83-86	Protein phosphatase 2C family protein	Arabidopsis thaliana	39-43
11208021-8	2001	These data indicate that the wild-type ABI2 phosphatase is a negative regulator of ABA signalling, and that the ABI1 and ABI2 phosphatases have overlapping roles in controlling ABA action.	Abscisic Acid	177-180	Protein phosphatase 2C family protein	Arabidopsis thaliana	121-125
11208021-9	2001	Measurements of PP2C activity in plant extracts showed that the phosphatase activity of ABI1 and ABI2 increases in response to ABA.	Abscisic Acid	127-130	Protein phosphatase 2C family protein	Arabidopsis thaliana	97-101
11208021-10	2001	These results suggest that ABI1 and ABI2 act in a negative feedback regulatory loop of the ABA signalling pathway.	Abscisic Acid	91-94	Protein phosphatase 2C family protein	Arabidopsis thaliana	36-40
10872217-5	2000	To facilitate quantitative analysis of the genetic control of tissue-specific ABA- and desiccation-response pathways, we analyzed ABA- and mannitol-inducible expression of a carrot (Daucus carota L.) Dc3 promoter:uidA (beta-glucuronidase; GUS) chimaeric reporter (Dc3-GUS) in transgenic wild-type, ABA-deficient aba1, and ABA-insensitive abi1 and abi2 mutants.	Mannitol	139-147	Protein phosphatase 2C family protein	Arabidopsis thaliana	347-351
10872217-0	2000	The genes ABI1 and ABI2 are involved in abscisic acid- and drought-inducible expression of the Daucus carota L. Dc3 promoter in guard cells of transgenic Arabidopsis thaliana (L.) Heynh.	Abscisic Acid	40-53	Protein phosphatase 2C family protein	Arabidopsis thaliana	19-23
10872217-8	2000	Quantitative fluorometric GUS assays of leaf extracts showed that abi2 mutants responded less to exogenous ABA than did abi1 mutants, and abi2 mutants responded more to mannitol than did abi1 mutants.	Abscisic Acid	107-110	Protein phosphatase 2C family protein	Arabidopsis thaliana	66-70
10872217-1	2000	The ABA INSENSITIVE1 (ABI1) and ABI2 genes encode homologous type-2C protein phosphatases with redundant yet distinct functions in abscisic acid (ABA) responses.	Abscisic Acid	4-7	Protein phosphatase 2C family protein	Arabidopsis thaliana	32-36
10872217-1	2000	The ABA INSENSITIVE1 (ABI1) and ABI2 genes encode homologous type-2C protein phosphatases with redundant yet distinct functions in abscisic acid (ABA) responses.	Abscisic Acid	131-144	Protein phosphatase 2C family protein	Arabidopsis thaliana	32-36
10872217-8	2000	Quantitative fluorometric GUS assays of leaf extracts showed that abi2 mutants responded less to exogenous ABA than did abi1 mutants, and abi2 mutants responded more to mannitol than did abi1 mutants.	Mannitol	169-177	Protein phosphatase 2C family protein	Arabidopsis thaliana	138-142
10872217-1	2000	The ABA INSENSITIVE1 (ABI1) and ABI2 genes encode homologous type-2C protein phosphatases with redundant yet distinct functions in abscisic acid (ABA) responses.	Abscisic Acid	146-149	Protein phosphatase 2C family protein	Arabidopsis thaliana	32-36
10872217-2	2000	Results from Northern blot analysis showed that ABA- and mannitol-inducible expression of the COR47 and COR78/LTI78/RD29A (COR78) genes was more impaired in the abi2 mutant of Arabidopsis thaliana (L.) Heynh than in the abi1 mutant.	Abscisic Acid	48-51	Protein phosphatase 2C family protein	Arabidopsis thaliana	161-165
10872217-9	2000	We conclude that Dc3-GUS Arabidopsis is a tractable system in which to study tissue-specific ABA and drought signalling and suggest that ABI2 functions predominantly over ABI1 in COR78 and COR47 gene expression and guard-cell Dc3-GUS expression.	Abscisic Acid	93-96	Protein phosphatase 2C family protein	Arabidopsis thaliana	137-141
10872217-2	2000	Results from Northern blot analysis showed that ABA- and mannitol-inducible expression of the COR47 and COR78/LTI78/RD29A (COR78) genes was more impaired in the abi2 mutant of Arabidopsis thaliana (L.) Heynh than in the abi1 mutant.	Mannitol	57-65	Protein phosphatase 2C family protein	Arabidopsis thaliana	161-165
9869399-5	1998	For instance, the ABI1/ABI2 PP2Cs are central components in abscisic acid (ABA) signal transduction.	Abscisic Acid	60-73	Protein phosphatase 2C family protein	Arabidopsis thaliana	23-27
10787063-6	2000	The abi1 fca-1 and abi2 fca-1 double mutants flowered earlier than fca-1 implying a role for abscisic acid in floral repression.	Abscisic Acid	93-106	Protein phosphatase 2C family protein	Arabidopsis thaliana	19-23
9869399-5	1998	For instance, the ABI1/ABI2 PP2Cs are central components in abscisic acid (ABA) signal transduction.	Abscisic Acid	75-78	Protein phosphatase 2C family protein	Arabidopsis thaliana	23-27
9869399-6	1998	Arabidopsis mutants containing a single amino acid exchange in ABI1 or ABI2 show a reduced response to ABA.	Abscisic Acid	103-106	Protein phosphatase 2C family protein	Arabidopsis thaliana	71-75