PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 33662400-2 2021 The larger subunits SPTLC1 and SPTLC2/SPTLC3 together form the catalytic core while a smaller third subunit either SSSPTA or SSSPTB has been shown to increase the catalytic efficiency and provide substrate specificity for the fatty acyl-CoA substrates. Acyl Coenzyme A 226-240 serine palmitoyltransferase small subunit B Homo sapiens 125-131 34370101-7 2021 The ADMP-MD simulations show that all oxide molecules remain adsorbed on Ti-benzene complex during the simulations for the temperature range 300-500 K. The Ti-benzene complex shows considerable gas sensing properties at ambient conditions. Oxides 38-43 serine palmitoyltransferase small subunit B Homo sapiens 4-8 34370101-7 2021 The ADMP-MD simulations show that all oxide molecules remain adsorbed on Ti-benzene complex during the simulations for the temperature range 300-500 K. The Ti-benzene complex shows considerable gas sensing properties at ambient conditions. ti-benzene 73-83 serine palmitoyltransferase small subunit B Homo sapiens 4-8 34370101-7 2021 The ADMP-MD simulations show that all oxide molecules remain adsorbed on Ti-benzene complex during the simulations for the temperature range 300-500 K. The Ti-benzene complex shows considerable gas sensing properties at ambient conditions. ti-benzene 156-166 serine palmitoyltransferase small subunit B Homo sapiens 4-8 32330443-2 2020 We apply chemoproteomics to determine that gambogic acid binds to the regulatory small subunit B of the serine palmitoyltransferase complex (SPTSSB). gambogic acid 43-56 serine palmitoyltransferase small subunit B Homo sapiens 141-147 33313495-5 2020 We show that anti-androgens elevate de novo generation of sphingolipids via SPTSSB, a rate-limiting mediator of sphingolipid generation. Sphingolipids 58-71 serine palmitoyltransferase small subunit B Homo sapiens 76-82 33313495-5 2020 We show that anti-androgens elevate de novo generation of sphingolipids via SPTSSB, a rate-limiting mediator of sphingolipid generation. Sphingolipids 58-70 serine palmitoyltransferase small subunit B Homo sapiens 76-82 32330443-2 2020 We apply chemoproteomics to determine that gambogic acid binds to the regulatory small subunit B of the serine palmitoyltransferase complex (SPTSSB). Serine 104-110 serine palmitoyltransferase small subunit B Homo sapiens 141-147 30366192-7 2019 The stability of the SSZ tautomeric forms and their corresponding H-Bonded DMF complexes were examined employing the ADMP molecular dynamics approach. Dimethylformamide 75-78 serine palmitoyltransferase small subunit B Homo sapiens 117-121 30818152-6 2019 Additionally, the stability of OLZ: beta-CD complex was demonstrated employing ADMP molecular dynamic simulations over a timeframe of 500fs. betadex 36-43 serine palmitoyltransferase small subunit B Homo sapiens 79-83 30366192-12 2019 The ADMP-MD results verified that these complexes and the corresponding intra- and intermolecular HBs are stable over a timeframe of 100 femtosecond. femtosecond 137-148 serine palmitoyltransferase small subunit B Homo sapiens 4-8 23426370-4 2013 In combination with analysis of isoform chimera and site-directed mutagenesis, a single amino acid residue in this core (Met(25) in ssSPTa and Val(25) in ssSPTb) was identified which confers specificity for palmitoyl- or stearoyl-CoA, respectively, in both yeast and mammalian cells. Valine 143-146 serine palmitoyltransferase small subunit B Homo sapiens 154-160 28000372-1 2017 2-Azido-1,3-dimethylimidazolinium chloride (ADMC) and its corresponding hexafluorophosphate (ADMP) were found to be efficient diazo-transfer reagents to various organic compounds. 2-azido-1,3-dimethylimidazolinium chloride 0-42 serine palmitoyltransferase small subunit B Homo sapiens 93-97 28000372-1 2017 2-Azido-1,3-dimethylimidazolinium chloride (ADMC) and its corresponding hexafluorophosphate (ADMP) were found to be efficient diazo-transfer reagents to various organic compounds. admc 44-48 serine palmitoyltransferase small subunit B Homo sapiens 93-97 28000372-1 2017 2-Azido-1,3-dimethylimidazolinium chloride (ADMC) and its corresponding hexafluorophosphate (ADMP) were found to be efficient diazo-transfer reagents to various organic compounds. Hexafluorophosphate 72-91 serine palmitoyltransferase small subunit B Homo sapiens 93-97 28000372-4 2017 ADMC and ADMP reacted with 1,3-dicarbonyl compounds under mild basic conditions to give 2-diazo-1,3-dicarbonyl compounds in high yields, which were easily isolated in virtue of the high water solubility of the by-products. 1,3-dicarbonyl compounds 27-51 serine palmitoyltransferase small subunit B Homo sapiens 9-13 28000372-4 2017 ADMC and ADMP reacted with 1,3-dicarbonyl compounds under mild basic conditions to give 2-diazo-1,3-dicarbonyl compounds in high yields, which were easily isolated in virtue of the high water solubility of the by-products. 2-diazo-1,3-dicarbonyl compounds 88-120 serine palmitoyltransferase small subunit B Homo sapiens 9-13 28000372-4 2017 ADMC and ADMP reacted with 1,3-dicarbonyl compounds under mild basic conditions to give 2-diazo-1,3-dicarbonyl compounds in high yields, which were easily isolated in virtue of the high water solubility of the by-products. Water 186-191 serine palmitoyltransferase small subunit B Homo sapiens 9-13 28000372-5 2017 ADMP showed high diazo-transfer ability to primary amines even in the absence of metal salt such as Cu(II). Amines 51-57 serine palmitoyltransferase small subunit B Homo sapiens 0-4 28000372-5 2017 ADMP showed high diazo-transfer ability to primary amines even in the absence of metal salt such as Cu(II). metal salt 81-91 serine palmitoyltransferase small subunit B Homo sapiens 0-4 28000372-5 2017 ADMP showed high diazo-transfer ability to primary amines even in the absence of metal salt such as Cu(II). cu(ii) 100-106 serine palmitoyltransferase small subunit B Homo sapiens 0-4 26511889-7 2016 DFT-based ADMP, dynamic simulations have been performed to explore the dynamics of the protonation processes in LD and CD. Carbidopa 119-121 serine palmitoyltransferase small subunit B Homo sapiens 10-14 23426370-4 2013 In combination with analysis of isoform chimera and site-directed mutagenesis, a single amino acid residue in this core (Met(25) in ssSPTa and Val(25) in ssSPTb) was identified which confers specificity for palmitoyl- or stearoyl-CoA, respectively, in both yeast and mammalian cells. palmitoyl- or 207-220 serine palmitoyltransferase small subunit B Homo sapiens 154-160 23426370-4 2013 In combination with analysis of isoform chimera and site-directed mutagenesis, a single amino acid residue in this core (Met(25) in ssSPTa and Val(25) in ssSPTb) was identified which confers specificity for palmitoyl- or stearoyl-CoA, respectively, in both yeast and mammalian cells. stearoyl-coenzyme A 221-233 serine palmitoyltransferase small subunit B Homo sapiens 154-160 18004849-1 2007 A recently developed extended Lagrangian model employing localized basis functions and nonperiodic boundary conditions (GLOB/ADMP) was applied to the radicals issuing from the homolytic breaking of the C(alpha)-H(alpha) bond of glycine in aqueous solution at different pH values. Glycine 228-235 serine palmitoyltransferase small subunit B Homo sapiens 125-129 8575329-6 1995 Though development of dorsoanterior structures is suppressed when exogenous ADMP is injected, the gene is induced by lithium chloride treatment or activin, both of which are known to produce the opposite effect. Lithium Chloride 117-133 serine palmitoyltransferase small subunit B Homo sapiens 76-80