PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
22516715-3	2012	ZaUCP4 shows a high similarity to predicted insect UCP4 isoforms and known mammalian UCP4s, both at the nucleotide and amino acid sequence levels.	zaucp4	0-6	solute carrier family 25 member 27	Homo sapiens	51-55
20000716-7	2010	Binding of UCP4 to purine nucleotides was also different from other UCPs.	Purine Nucleotides	19-37	solute carrier family 25 member 27	Homo sapiens	11-15
19526295-2	2009	We previously reported that neural cells expressing the brain uncoupling protein UCP4 exhibit enhanced dependency on glucose for support of cellular bioenergetics and survival.	Glucose	117-124	solute carrier family 25 member 27	Homo sapiens	81-85
19526295-6	2009	Pharmacological inhibition of ERKs not only abrogated bioenergetics adaptation but also reduced the activation of cAMP-responsive element-binding (CREB) protein suggesting that CREB protein signaling contributes in part to UCP4-dependent cell death rescue from 3-nitropropionic acid-induced toxicity.	3-nitropropionic acid	261-282	solute carrier family 25 member 27	Homo sapiens	223-227
17035241-0	2006	Mitochondrial uncoupling protein-4 regulates calcium homeostasis and sensitivity to store depletion-induced apoptosis in neural cells.	Calcium	45-52	solute carrier family 25 member 27	Homo sapiens	0-34
17035241-5	2006	PC12 neural cells expressing human UCP4 exhibit reduced Ca(2+) entry in response to thapsigargin-induced endoplasmic reticulum Ca(2+) store depletion.	Thapsigargin	84-96	solute carrier family 25 member 27	Homo sapiens	35-39
17035241-6	2006	The elevations of cytoplasmic and intramitochondrial Ca(2+) concentrations and mitochondrial oxidative stress induced by thapsigargin were attenuated in cells expressing UCP4.	Thapsigargin	121-133	solute carrier family 25 member 27	Homo sapiens	170-174
17035241-7	2006	The stabilization of Ca(2+) homeostasis and preservation of mitochondrial function by UCP4 was correlated with reduced mitochondrial reactive oxygen species generation, oxidative stress, and Gadd153 up-regulation and increased resistance of the cells to death.	Reactive Oxygen Species	133-156	solute carrier family 25 member 27	Homo sapiens	86-90
17035241-8	2006	Reduced Ca(2+)-dependent cytosolic phospholipase A2 activation and oxidative metabolism of arachidonic acid also contributed to the stabilization of mitochondrial function in cells expressing human UCP4.	Arachidonic Acid	91-107	solute carrier family 25 member 27	Homo sapiens	198-202
15948157-5	2005	The increase in ROS production may be attenuated by UCP4 and UCP5 up-regulation.	Reactive Oxygen Species	16-19	solute carrier family 25 member 27	Homo sapiens	52-56
12729589-8	2003	We have found that UCP-4 protects neurons against apoptosis by a mechanism involving suppression of oxyradical production and stabilization of cellular calcium homeostasis.	Calcium	152-159	solute carrier family 25 member 27	Homo sapiens	19-24
35431771-5	2022	We identified Primary bile acid biosynthesis as the major biochemical pathway to be perturbed in the frontal lobe of PD sufferers, and the metabolite taurine (p-value = 5.91E-06) as being positively correlated with CpG cg14286187 (SLC25A27; CYP39A1) (FDR q = 0.002), highlighting previously unreported biochemical changes associated with PD pathogenesis.	Bile Acids and Salts	22-31	solute carrier family 25 member 27	Homo sapiens	231-239
35431771-5	2022	We identified Primary bile acid biosynthesis as the major biochemical pathway to be perturbed in the frontal lobe of PD sufferers, and the metabolite taurine (p-value = 5.91E-06) as being positively correlated with CpG cg14286187 (SLC25A27; CYP39A1) (FDR q = 0.002), highlighting previously unreported biochemical changes associated with PD pathogenesis.	Taurine	150-157	solute carrier family 25 member 27	Homo sapiens	231-239
29315581-6	2018	We found that UCP4 was up-regulated upon 1-methyl-4-phenylpyridinium (MPP+ ) stimulation in SH-SY5Y cells, which was enhanced by wild type DJ-1 and alleviated by DJ-1 knockdown.	1-Methyl-4-phenylpyridinium	41-68	solute carrier family 25 member 27	Homo sapiens	14-18
29315581-6	2018	We found that UCP4 was up-regulated upon 1-methyl-4-phenylpyridinium (MPP+ ) stimulation in SH-SY5Y cells, which was enhanced by wild type DJ-1 and alleviated by DJ-1 knockdown.	mangion-purified polysaccharide (Candida albicans)	70-74	solute carrier family 25 member 27	Homo sapiens	14-18
26934480-2	2016	Uncoupling protein 4 (UCP4) can protect cells against oxidative stress via reducing ROS production and cell apoptosis.	Reactive Oxygen Species	84-87	solute carrier family 25 member 27	Homo sapiens	0-20
26934480-2	2016	Uncoupling protein 4 (UCP4) can protect cells against oxidative stress via reducing ROS production and cell apoptosis.	Reactive Oxygen Species	84-87	solute carrier family 25 member 27	Homo sapiens	22-26
26934480-3	2016	Here, silencing of UCP4 in primary chondrocytes significantly inhibited cell survival, but induced ROS production and cell apoptosis.	Reactive Oxygen Species	99-102	solute carrier family 25 member 27	Homo sapiens	19-23
26934480-8	2016	In conclusion, UCP4, whose expression was suppressed by leptin, may be involved in the ROS production and apoptosis of chondrocytes, thus contributing to the OA pathogenesis.	Reactive Oxygen Species	87-90	solute carrier family 25 member 27	Homo sapiens	15-19
26548865-0	2016	Activation of Mitochondrial Uncoupling Protein 4 and ATP-Sensitive Potassium Channel Cumulatively Decreases Superoxide Production in Insect Mitochondria.	Superoxides	108-118	solute carrier family 25 member 27	Homo sapiens	14-48
26548865-1	2016	It has been evidenced that mitochondrial uncoupling protein 4 (UCP4) and ATP-regulated potassium channel (mKATP channel) of insect Gromphadorhina coqereliana mitochondria decrease superoxide anion production.	Superoxides	180-196	solute carrier family 25 member 27	Homo sapiens	27-61
26548865-1	2016	It has been evidenced that mitochondrial uncoupling protein 4 (UCP4) and ATP-regulated potassium channel (mKATP channel) of insect Gromphadorhina coqereliana mitochondria decrease superoxide anion production.	Superoxides	180-196	solute carrier family 25 member 27	Homo sapiens	63-67
26548865-3	2016	Our data show that the simultaneous activation of UCP4 by palmitic acid and mKATP channel by pinacidil revealed a cumulative effect on weakening mitochondrial superoxide formation.	Palmitic Acid	58-71	solute carrier family 25 member 27	Homo sapiens	50-54
26548865-3	2016	Our data show that the simultaneous activation of UCP4 by palmitic acid and mKATP channel by pinacidil revealed a cumulative effect on weakening mitochondrial superoxide formation.	Pinacidil	93-102	solute carrier family 25 member 27	Homo sapiens	50-54
26548865-3	2016	Our data show that the simultaneous activation of UCP4 by palmitic acid and mKATP channel by pinacidil revealed a cumulative effect on weakening mitochondrial superoxide formation.	Superoxides	159-169	solute carrier family 25 member 27	Homo sapiens	50-54
26548865-4	2016	The inhibition of UCP4 by GTP (and/or ATP) and mKATP channel by ATP elevated superoxide production.	Guanosine Triphosphate	26-29	solute carrier family 25 member 27	Homo sapiens	18-22
26548865-4	2016	The inhibition of UCP4 by GTP (and/or ATP) and mKATP channel by ATP elevated superoxide production.	Adenosine Triphosphate	38-41	solute carrier family 25 member 27	Homo sapiens	18-22
26548865-4	2016	The inhibition of UCP4 by GTP (and/or ATP) and mKATP channel by ATP elevated superoxide production.	Adenosine Triphosphate	49-52	solute carrier family 25 member 27	Homo sapiens	18-22
26548865-4	2016	The inhibition of UCP4 by GTP (and/or ATP) and mKATP channel by ATP elevated superoxide production.	Superoxides	77-87	solute carrier family 25 member 27	Homo sapiens	18-22
25237189-8	2014	In brief, we found that UCP4 regulates the intramitochondrial pH of astrocytes, which acidifies as a consequence of glutamate uptake, with the main consequence of reducing efficiency of mitochondrial ATP production.	Glutamic Acid	116-125	solute carrier family 25 member 27	Homo sapiens	24-28
25237189-8	2014	In brief, we found that UCP4 regulates the intramitochondrial pH of astrocytes, which acidifies as a consequence of glutamate uptake, with the main consequence of reducing efficiency of mitochondrial ATP production.	Adenosine Triphosphate	200-203	solute carrier family 25 member 27	Homo sapiens	24-28
25237189-11	2014	We show that astrocytes expressing more UCP4 produced more lactate, which is used as an energy source by neurons, and had the ability to enhance neuronal survival.	Lactic Acid	59-66	solute carrier family 25 member 27	Homo sapiens	40-44
19361273-4	2009	It was found that UCP2 and UCP4 protein levels were upregulated in neo but downregulated in APP and APPsw cells by the superoxide anion.	Superoxides	119-135	solute carrier family 25 member 27	Homo sapiens	27-31
19361273-5	2009	Our results show that the superoxide anion can regulate protein levels of UCP2 and UCP4 in SH-SY5Y cells, and the mitochondrial free Ca(2+) shifted their levels, tightly coupled with the protein levels of UCPs.	Superoxides	26-42	solute carrier family 25 member 27	Homo sapiens	83-87
19150400-0	2009	Mitochondrial UCP4 attenuates MPP+ - and dopamine-induced oxidative stress, mitochondrial depolarization, and ATP deficiency in neurons and is interlinked with UCP2 expression.	Dopamine	41-49	solute carrier family 25 member 27	Homo sapiens	14-18
19150400-0	2009	Mitochondrial UCP4 attenuates MPP+ - and dopamine-induced oxidative stress, mitochondrial depolarization, and ATP deficiency in neurons and is interlinked with UCP2 expression.	Adenosine Triphosphate	110-113	solute carrier family 25 member 27	Homo sapiens	14-18
19150400-2	2009	We explored the neuroprotective role of UCP4 with its stable overexpression in SH-SY5Y cells, after exposure to either MPP(+) or dopamine to induce ATP deficiency and oxidative stress.	Dopamine	129-137	solute carrier family 25 member 27	Homo sapiens	40-44
19150400-3	2009	Cells overexpressing UCP4 proliferated faster in normal cultures and after exposure to MPP(+) and dopamine.	Dopamine	98-106	solute carrier family 25 member 27	Homo sapiens	21-25
19150400-5	2009	Contrary to the mild uncoupling hypothesis, UCP4 overexpression resulted in increased absolute ATP levels (with ADP/ATP ratios similar to those of controls under normal conditions and ADP supplementation) associated with increased respiration rate.	Adenosine Triphosphate	95-98	solute carrier family 25 member 27	Homo sapiens	44-48
19150400-5	2009	Contrary to the mild uncoupling hypothesis, UCP4 overexpression resulted in increased absolute ATP levels (with ADP/ATP ratios similar to those of controls under normal conditions and ADP supplementation) associated with increased respiration rate.	Adenosine Diphosphate	112-115	solute carrier family 25 member 27	Homo sapiens	44-48
19150400-5	2009	Contrary to the mild uncoupling hypothesis, UCP4 overexpression resulted in increased absolute ATP levels (with ADP/ATP ratios similar to those of controls under normal conditions and ADP supplementation) associated with increased respiration rate.	Adenosine Triphosphate	116-119	solute carrier family 25 member 27	Homo sapiens	44-48
19150400-5	2009	Contrary to the mild uncoupling hypothesis, UCP4 overexpression resulted in increased absolute ATP levels (with ADP/ATP ratios similar to those of controls under normal conditions and ADP supplementation) associated with increased respiration rate.	Adenosine Diphosphate	184-187	solute carrier family 25 member 27	Homo sapiens	44-48
19150400-6	2009	Under MPP(+) toxicity, UCP4 overexpression preserved ATP levels and mitochondrial membrane potential (MMP) and reduced oxidative stress; the preserved ATP level was not due to increased glycolysis.	Adenosine Triphosphate	53-56	solute carrier family 25 member 27	Homo sapiens	23-27
19150400-6	2009	Under MPP(+) toxicity, UCP4 overexpression preserved ATP levels and mitochondrial membrane potential (MMP) and reduced oxidative stress; the preserved ATP level was not due to increased glycolysis.	Adenosine Triphosphate	151-154	solute carrier family 25 member 27	Homo sapiens	23-27
19150400-9	2009	UCP4 overexpression increases cell survival by inducing oxidative phosphorylation, preserving ATP synthesis and MMP, and reducing oxidative stress.	Adenosine Triphosphate	94-97	solute carrier family 25 member 27	Homo sapiens	0-4
31054074-4	2019	DJ-1 increases the expression of two mitochondrial uncoupling proteins (UCP 4 and UCP5), that decrease mitochondrial membrane potential and leads to the suppression of ROS production, optimizes of a number of mitochondrial functions, and is regarded as protection for the neuronal cell survival.	ros	168-171	solute carrier family 25 member 27	Homo sapiens	72-77
22580300-1	2012	Mitochondrial uncoupling protein-4 (UCP4) enhances neuronal survival in 1-methyl-4-phenylpyridinium (MPP(+)) toxicity by suppressing oxidative stress and preserving intracellular ATP and mitochondrial membrane potential (MMP).	mangion-purified polysaccharide (Candida albicans)	101-104	solute carrier family 25 member 27	Homo sapiens	36-40
22580300-1	2012	Mitochondrial uncoupling protein-4 (UCP4) enhances neuronal survival in 1-methyl-4-phenylpyridinium (MPP(+)) toxicity by suppressing oxidative stress and preserving intracellular ATP and mitochondrial membrane potential (MMP).	Adenosine Triphosphate	179-182	solute carrier family 25 member 27	Homo sapiens	0-34
22580300-1	2012	Mitochondrial uncoupling protein-4 (UCP4) enhances neuronal survival in 1-methyl-4-phenylpyridinium (MPP(+)) toxicity by suppressing oxidative stress and preserving intracellular ATP and mitochondrial membrane potential (MMP).	1-Methyl-4-phenylpyridinium	72-99	solute carrier family 25 member 27	Homo sapiens	0-34
22580300-1	2012	Mitochondrial uncoupling protein-4 (UCP4) enhances neuronal survival in 1-methyl-4-phenylpyridinium (MPP(+)) toxicity by suppressing oxidative stress and preserving intracellular ATP and mitochondrial membrane potential (MMP).	1-Methyl-4-phenylpyridinium	72-99	solute carrier family 25 member 27	Homo sapiens	36-40
22580300-1	2012	Mitochondrial uncoupling protein-4 (UCP4) enhances neuronal survival in 1-methyl-4-phenylpyridinium (MPP(+)) toxicity by suppressing oxidative stress and preserving intracellular ATP and mitochondrial membrane potential (MMP).	Adenosine Triphosphate	179-182	solute carrier family 25 member 27	Homo sapiens	36-40
22580300-1	2012	Mitochondrial uncoupling protein-4 (UCP4) enhances neuronal survival in 1-methyl-4-phenylpyridinium (MPP(+)) toxicity by suppressing oxidative stress and preserving intracellular ATP and mitochondrial membrane potential (MMP).	mangion-purified polysaccharide (Candida albicans)	101-104	solute carrier family 25 member 27	Homo sapiens	0-34
22580300-7	2012	Electrophoretic mobility shift assay showed that H(2)O(2) increased NF-kappaB binding to the UCP4 promoter and that NF-kappaB complexes were composed of p50/p50 and p50/c-Rel dimers.	Hydrogen Peroxide	49-57	solute carrier family 25 member 27	Homo sapiens	93-97
22580300-8	2012	Under H(2)O(2)-induced oxidative stress, UCP4 knockdown significantly increased superoxide levels, decreased reduced glutathione (GSH) levels, and increased oxidized glutathione levels, compared to controls.	Hydrogen Peroxide	6-14	solute carrier family 25 member 27	Homo sapiens	41-45
22580300-8	2012	Under H(2)O(2)-induced oxidative stress, UCP4 knockdown significantly increased superoxide levels, decreased reduced glutathione (GSH) levels, and increased oxidized glutathione levels, compared to controls.	Superoxides	80-90	solute carrier family 25 member 27	Homo sapiens	41-45
22580300-8	2012	Under H(2)O(2)-induced oxidative stress, UCP4 knockdown significantly increased superoxide levels, decreased reduced glutathione (GSH) levels, and increased oxidized glutathione levels, compared to controls.	Glutathione	117-128	solute carrier family 25 member 27	Homo sapiens	41-45
22580300-8	2012	Under H(2)O(2)-induced oxidative stress, UCP4 knockdown significantly increased superoxide levels, decreased reduced glutathione (GSH) levels, and increased oxidized glutathione levels, compared to controls.	Glutathione	130-133	solute carrier family 25 member 27	Homo sapiens	41-45
22580300-8	2012	Under H(2)O(2)-induced oxidative stress, UCP4 knockdown significantly increased superoxide levels, decreased reduced glutathione (GSH) levels, and increased oxidized glutathione levels, compared to controls.	Glutathione	166-177	solute carrier family 25 member 27	Homo sapiens	41-45
22580300-9	2012	UCP4 expression induced by c-Rel overexpression significantly decreased superoxide levels and preserved GSH levels and MMP under similar stress.	Superoxides	72-82	solute carrier family 25 member 27	Homo sapiens	0-4
22580300-9	2012	UCP4 expression induced by c-Rel overexpression significantly decreased superoxide levels and preserved GSH levels and MMP under similar stress.	Glutathione	104-107	solute carrier family 25 member 27	Homo sapiens	0-4
22580300-10	2012	These protective effects of c-Rel overexpression in H(2)O(2)-induced oxidative stress were significantly reduced after UCP4 knockdown, indicating that UCP4 is a target effector gene of the NF-kappaB c-Rel prosurvival pathway to mitigate the effects of oxidative stress.	Hydrogen Peroxide	52-60	solute carrier family 25 member 27	Homo sapiens	119-123
22580300-10	2012	These protective effects of c-Rel overexpression in H(2)O(2)-induced oxidative stress were significantly reduced after UCP4 knockdown, indicating that UCP4 is a target effector gene of the NF-kappaB c-Rel prosurvival pathway to mitigate the effects of oxidative stress.	Hydrogen Peroxide	52-60	solute carrier family 25 member 27	Homo sapiens	151-155
21332312-7	2011	However, one haplotype spanning UCP4 was found to be significantly under-represented in URS patients.	Peptichemio	88-91	solute carrier family 25 member 27	Homo sapiens	32-36
22427795-0	2012	Uncoupling protein-4 (UCP4) increases ATP supply by interacting with mitochondrial Complex II in neuroblastoma cells.	Adenosine Triphosphate	38-41	solute carrier family 25 member 27	Homo sapiens	0-20
22427795-0	2012	Uncoupling protein-4 (UCP4) increases ATP supply by interacting with mitochondrial Complex II in neuroblastoma cells.	Adenosine Triphosphate	38-41	solute carrier family 25 member 27	Homo sapiens	22-26
22427795-1	2012	Mitochondrial uncoupling protein-4 (UCP4) protects against Complex I deficiency as induced by 1-methyl-4-phenylpyridinium (MPP(+)), but how UCP4 affects mitochondrial function is unclear.	1-Methyl-4-phenylpyridinium	94-121	solute carrier family 25 member 27	Homo sapiens	0-34
22427795-1	2012	Mitochondrial uncoupling protein-4 (UCP4) protects against Complex I deficiency as induced by 1-methyl-4-phenylpyridinium (MPP(+)), but how UCP4 affects mitochondrial function is unclear.	1-Methyl-4-phenylpyridinium	94-121	solute carrier family 25 member 27	Homo sapiens	36-40
22427795-1	2012	Mitochondrial uncoupling protein-4 (UCP4) protects against Complex I deficiency as induced by 1-methyl-4-phenylpyridinium (MPP(+)), but how UCP4 affects mitochondrial function is unclear.	mangion-purified polysaccharide (Candida albicans)	123-126	solute carrier family 25 member 27	Homo sapiens	0-34
22427795-1	2012	Mitochondrial uncoupling protein-4 (UCP4) protects against Complex I deficiency as induced by 1-methyl-4-phenylpyridinium (MPP(+)), but how UCP4 affects mitochondrial function is unclear.	mangion-purified polysaccharide (Candida albicans)	123-126	solute carrier family 25 member 27	Homo sapiens	36-40
22427795-3	2012	Cells stably overexpressing UCP4 exhibited higher oxygen consumption (10.1%, p<0.01), with 20% greater proton leak than vector controls (p<0.01).	Oxygen	50-56	solute carrier family 25 member 27	Homo sapiens	28-32
22427795-4	2012	Increased ATP supply was observed in UCP4-overexpressing cells compared to controls (p<0.05).	Adenosine Triphosphate	10-13	solute carrier family 25 member 27	Homo sapiens	37-41
22427795-6	2012	Mitochondrial ADP consumption by succinate-induced respiration was 26% higher in UCP4-overexpressing cells, with 20% higher ADP:O ratio (p<0.05).	Adenosine Diphosphate	14-17	solute carrier family 25 member 27	Homo sapiens	81-85
22427795-6	2012	Mitochondrial ADP consumption by succinate-induced respiration was 26% higher in UCP4-overexpressing cells, with 20% higher ADP:O ratio (p<0.05).	Succinic Acid	33-42	solute carrier family 25 member 27	Homo sapiens	81-85
22427795-6	2012	Mitochondrial ADP consumption by succinate-induced respiration was 26% higher in UCP4-overexpressing cells, with 20% higher ADP:O ratio (p<0.05).	Adenosine Diphosphate	124-127	solute carrier family 25 member 27	Homo sapiens	81-85
22427795-9	2012	Our findings elucidate how UCP4 overexpression increases ATP synthesis by specifically interacting with Complex II.	Adenosine Triphosphate	57-60	solute carrier family 25 member 27	Homo sapiens	27-31
22427795-10	2012	This highlights a unique role of UCP4 as a potential regulatory target to modulate mitochondrial Complex II and ATP output in preserving existing neurons against energy crisis.	Adenosine Triphosphate	112-115	solute carrier family 25 member 27	Homo sapiens	33-37
21997226-10	2011	LC-MS/MS analyses revealed 100% sequence identities for peptides obtained from GcUCP to UCP4 isoforms from D. melanogaster (the highest homology), human, rat or other insect mitochondria.	Peptides	56-64	solute carrier family 25 member 27	Homo sapiens	88-92
21332312-9	2011	CONCLUSION: Although our sample is of limited size and not representative of schizophrenia as a whole, the association found between the URS group and the UCP4 haplotype is noteworthy as it may influence treatment outcome in schizophrenia.	Peptichemio	137-140	solute carrier family 25 member 27	Homo sapiens	155-159
20385226-0	2010	Transcriptional regulation of UCP4 by NF-kappaB and its role in mediating protection against MPP+ toxicity.	mangion-purified polysaccharide (Candida albicans)	93-96	solute carrier family 25 member 27	Homo sapiens	30-34
20385226-1	2010	Mitochondrial uncoupling protein-4 (UCP4) enhances neuronal cell survival in MPP(+)-induced toxicity by suppressing oxidative stress and preserving intracellular ATP and mitochondrial membrane potential.	mangion-purified polysaccharide (Candida albicans)	77-83	solute carrier family 25 member 27	Homo sapiens	0-34
20385226-1	2010	Mitochondrial uncoupling protein-4 (UCP4) enhances neuronal cell survival in MPP(+)-induced toxicity by suppressing oxidative stress and preserving intracellular ATP and mitochondrial membrane potential.	mangion-purified polysaccharide (Candida albicans)	77-83	solute carrier family 25 member 27	Homo sapiens	36-40
20385226-1	2010	Mitochondrial uncoupling protein-4 (UCP4) enhances neuronal cell survival in MPP(+)-induced toxicity by suppressing oxidative stress and preserving intracellular ATP and mitochondrial membrane potential.	Adenosine Triphosphate	162-165	solute carrier family 25 member 27	Homo sapiens	0-34
20385226-1	2010	Mitochondrial uncoupling protein-4 (UCP4) enhances neuronal cell survival in MPP(+)-induced toxicity by suppressing oxidative stress and preserving intracellular ATP and mitochondrial membrane potential.	Adenosine Triphosphate	162-165	solute carrier family 25 member 27	Homo sapiens	36-40
20385226-8	2010	Activation of NF-kappaB by TNFalpha or cycloheximide increased, whereas its inhibition by 4-hydroxy-2-nonenal or transfection of pIkappaBalphaM suppressed, UCP4 promoter activity.	Cycloheximide	39-52	solute carrier family 25 member 27	Homo sapiens	156-160
20385226-8	2010	Activation of NF-kappaB by TNFalpha or cycloheximide increased, whereas its inhibition by 4-hydroxy-2-nonenal or transfection of pIkappaBalphaM suppressed, UCP4 promoter activity.	4-hydroxy-2-nonenal	90-109	solute carrier family 25 member 27	Homo sapiens	156-160
20385226-8	2010	Activation of NF-kappaB by TNFalpha or cycloheximide increased, whereas its inhibition by 4-hydroxy-2-nonenal or transfection of pIkappaBalphaM suppressed, UCP4 promoter activity.	pikappabalpham	129-143	solute carrier family 25 member 27	Homo sapiens	156-160
20490313-10	2010	On the other hand, our study has shown that UCP2 and UCP4 have important impact on mitochondrial calcium concentration of nerve cells, suggesting that their abnormal expression may involve in the pathogenesis of Alzheimer"s disease.	Calcium	97-104	solute carrier family 25 member 27	Homo sapiens	53-57