PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
2981392-2	1985	In the present research we have extended our work on the presence of binding sites for prolactin in the rabbit brain focusing our attention on the brain areas with high dopamine cell bodies density.	Dopamine	169-177	prolactin	Oryctolagus cuniculus	87-96
6512768-0	1984	Prolactin as a factor in the uterine response to progesterone in rabbits.	Progesterone	49-61	prolactin	Oryctolagus cuniculus	0-9
6512768-7	1984	These results suggest that prolactin acts as an essential factor in the rabbit uterine response to progesterone, perhaps by the modulation of progesterone receptor activity.	Progesterone	99-111	prolactin	Oryctolagus cuniculus	27-36
6432592-4	1984	However, in spite of no changes in LH and FSH, short-term PRL administration lowered the serum testosterone (T) in intact animals.	Testosterone	95-107	prolactin	Oryctolagus cuniculus	58-61
6432592-7	1984	All of these studies indicate that PRL interferes with the testicular response to LH.	Luteinizing Hormone	82-84	prolactin	Oryctolagus cuniculus	35-38
6432592-8	1984	The fact that LH and FSH did not rise in response to the lowered T in intact animals suggested that PRL also altered the steroid feedback control of LH and FSH secretion.	Steroids	121-128	prolactin	Oryctolagus cuniculus	100-103
6432592-11	1984	These studies indicate that PRL acts at at least two sites in the reproductive system in rabbits: (1) directly at a gonadal level by interfering with gonadotropin action and (2) at a hypothalamic-pituitary central level by preventing the expected rise in gonadotropins in response to low gonadal steroids.	Steroids	296-304	prolactin	Oryctolagus cuniculus	28-31
6690286-8	1984	Suckling failed to elicit any PRL release on day 30, but the administration of fluphenazine, a dopamine antagonist, did cause a rise in plasma PRL.	Fluphenazine	79-91	prolactin	Oryctolagus cuniculus	143-146
6690286-8	1984	Suckling failed to elicit any PRL release on day 30, but the administration of fluphenazine, a dopamine antagonist, did cause a rise in plasma PRL.	Dopamine	95-103	prolactin	Oryctolagus cuniculus	143-146
6889009-0	1983	Prolactin: a hormonal regulator of the neonatal tissue water reservoir.	Water	55-60	prolactin	Oryctolagus cuniculus	0-9
6714651-1	1984	Prolactin from chinook salmon pituitaries was purified by acid acetone extraction, saline precipitation, chromatofocusing, and gel filtration.	acid acetone	58-70	prolactin	Oryctolagus cuniculus	0-9
6714651-1	1984	Prolactin from chinook salmon pituitaries was purified by acid acetone extraction, saline precipitation, chromatofocusing, and gel filtration.	Sodium Chloride	83-89	prolactin	Oryctolagus cuniculus	0-9
6714651-2	1984	This procedure allowed us to recover highly purified prolactin as demonstrated by the presence of a single NH2-terminal amino acid and a single band in sodium dodecyl sulfate gel electrophoresis.	Sodium Dodecyl Sulfate	152-174	prolactin	Oryctolagus cuniculus	53-62
6714651-5	1984	The prolactin character of the purified protein was established by its lactogenic activity in the rabbit mammary gland in vitro and its sodium-retaining activity in hypophysectomized Fundulus heteroclitus.	Sodium	136-142	prolactin	Oryctolagus cuniculus	4-13
6644231-3	1983	Prolactin degradation was followed after intravenous injection of 125I-labelled ovine prolactin.	Iodine-125	66-70	prolactin	Oryctolagus cuniculus	0-9
6644231-3	1983	Prolactin degradation was followed after intravenous injection of 125I-labelled ovine prolactin.	Iodine-125	66-70	prolactin	Oryctolagus cuniculus	86-95
6466748-1	1984	We treated neonatal rabbits from birth with exogenous prolactin or the prolactin secretagogue fluphenazine.	Fluphenazine	94-106	prolactin	Oryctolagus cuniculus	71-80
6655409-0	1983	Effect of nigericin and varying potassium concentrations on the prolactin-stimulated synthesis of milk fat in explants of mammary alveolar tissue from rabbits.	Nigericin	10-19	prolactin	Oryctolagus cuniculus	64-73
6655409-0	1983	Effect of nigericin and varying potassium concentrations on the prolactin-stimulated synthesis of milk fat in explants of mammary alveolar tissue from rabbits.	Potassium	32-41	prolactin	Oryctolagus cuniculus	64-73
6655409-4	1983	Increase in the rate of fatty acid synthesis in the presence of prolactin was used as a marker of prolactin stimulation.	Fatty Acids	24-34	prolactin	Oryctolagus cuniculus	98-107
6655409-5	1983	At low K+ concentrations prolactin-stimulated fatty acid synthesis decreased with the decrease in K+ concentration of the media, whereas there was no similar trend in the rate of protein synthesis.	Fatty Acids	46-56	prolactin	Oryctolagus cuniculus	25-34
6889009-1	1983	Groups of newborn rabbits were treated with exogenous prolactin, with fluphenazine (a stimulant of endogenous prolactin secretion) with bromocriptine (a blocker of endogenous prolactin secretion), or with bromocriptine plus exogenous prolactin, and lean body hydration in these animals was compared with that of untreated controls.	Fluphenazine	70-82	prolactin	Oryctolagus cuniculus	110-119
6889009-1	1983	Groups of newborn rabbits were treated with exogenous prolactin, with fluphenazine (a stimulant of endogenous prolactin secretion) with bromocriptine (a blocker of endogenous prolactin secretion), or with bromocriptine plus exogenous prolactin, and lean body hydration in these animals was compared with that of untreated controls.	Fluphenazine	70-82	prolactin	Oryctolagus cuniculus	110-119
6889009-1	1983	Groups of newborn rabbits were treated with exogenous prolactin, with fluphenazine (a stimulant of endogenous prolactin secretion) with bromocriptine (a blocker of endogenous prolactin secretion), or with bromocriptine plus exogenous prolactin, and lean body hydration in these animals was compared with that of untreated controls.	Fluphenazine	70-82	prolactin	Oryctolagus cuniculus	110-119
6889009-2	1983	Animals treated with prolactin or fluphenazine retained more water than did the controls.	Water	61-66	prolactin	Oryctolagus cuniculus	21-30
6889009-4	1983	Exogenous prolactin abolished the effect of bromocriptine.	Bromocriptine	44-57	prolactin	Oryctolagus cuniculus	10-19
6299794-0	1983	Effect of sodium butyrate on the stimulation of casein gene expression by prolactin.	Butyric Acid	10-25	prolactin	Oryctolagus cuniculus	74-83
6299794-1	1983	Sodium butyrate, but not isobutyrate, inhibits prolactin action on the induction of casein synthesis and casein mRNA accumulation in rabbit mammary explants.	Butyric Acid	0-15	prolactin	Oryctolagus cuniculus	47-56
6299794-2	1983	Sodium butyrate specifically prevents the generation of the prolactin relay which can be released from isolated membranes incubated with prolactin and which stimulates directly casein gene transcription when added to isolated mammary nuclei.	Butyric Acid	0-15	prolactin	Oryctolagus cuniculus	60-69
6299794-2	1983	Sodium butyrate specifically prevents the generation of the prolactin relay which can be released from isolated membranes incubated with prolactin and which stimulates directly casein gene transcription when added to isolated mammary nuclei.	Butyric Acid	0-15	prolactin	Oryctolagus cuniculus	137-146
6404170-1	1983	In the rabbit model of the ovarian hyperstimulation syndrome, animals given ovine prolactin with human menopausal gonadotropins (hMGs), as compared to animals receiving hMGs alone, demonstrated an increase in the formation of ascitic fluid, a decrease in mean plasma estradiol, and an increase in the mean plasma progesterone concentrations.	Progesterone	313-325	prolactin	Oryctolagus cuniculus	82-91
6188649-1	1983	A highly purified prolactin (PRL) was isolated from the chum salmon pituitary by extraction with acid acetone, gel filtration on Sephadex G-25 and ion-exchange chromatography on CM-Sephadex C-25 with a yield of 1 mg/g of wet tissue.	acid acetone	97-109	prolactin	Oryctolagus cuniculus	29-32
6188649-1	1983	A highly purified prolactin (PRL) was isolated from the chum salmon pituitary by extraction with acid acetone, gel filtration on Sephadex G-25 and ion-exchange chromatography on CM-Sephadex C-25 with a yield of 1 mg/g of wet tissue.	sephadex	129-142	prolactin	Oryctolagus cuniculus	29-32
6188649-1	1983	A highly purified prolactin (PRL) was isolated from the chum salmon pituitary by extraction with acid acetone, gel filtration on Sephadex G-25 and ion-exchange chromatography on CM-Sephadex C-25 with a yield of 1 mg/g of wet tissue.	sephadex c-25	181-194	prolactin	Oryctolagus cuniculus	29-32
6188649-3	1983	The salmon PRL emerged as a single and symmetrical peak on Sephadex G-100 with Ve/Vo = 2.0.	sephadex	59-73	prolactin	Oryctolagus cuniculus	11-14
6188649-7	1983	The salmon PRL had a molecular weight of 23,400 daltons by gel filtration and 22,300 daltons by sodium dodecyl sulfate gel electrophoresis, with a single NH2-terminal residue, isoleucine, and a single COOH-terminal residue, half-cystine.	Sodium Dodecyl Sulfate	96-118	prolactin	Oryctolagus cuniculus	11-14
6188649-7	1983	The salmon PRL had a molecular weight of 23,400 daltons by gel filtration and 22,300 daltons by sodium dodecyl sulfate gel electrophoresis, with a single NH2-terminal residue, isoleucine, and a single COOH-terminal residue, half-cystine.	Isoleucine	176-186	prolactin	Oryctolagus cuniculus	11-14
6188649-7	1983	The salmon PRL had a molecular weight of 23,400 daltons by gel filtration and 22,300 daltons by sodium dodecyl sulfate gel electrophoresis, with a single NH2-terminal residue, isoleucine, and a single COOH-terminal residue, half-cystine.	Carbonic Acid	201-205	prolactin	Oryctolagus cuniculus	11-14
6188649-7	1983	The salmon PRL had a molecular weight of 23,400 daltons by gel filtration and 22,300 daltons by sodium dodecyl sulfate gel electrophoresis, with a single NH2-terminal residue, isoleucine, and a single COOH-terminal residue, half-cystine.	Cystine	229-236	prolactin	Oryctolagus cuniculus	11-14
7086239-5	1982	These findings suggest that PRL activates TG synthesis in liver and consequently increases serum TG levels.	Triglycerides	42-44	prolactin	Oryctolagus cuniculus	28-31
6827904-6	1983	Plasma prolactin concentrations increased after injection of both chlorpromazine and sulpiride.	Chlorpromazine	66-80	prolactin	Oryctolagus cuniculus	7-16
6827904-6	1983	Plasma prolactin concentrations increased after injection of both chlorpromazine and sulpiride.	Sulpiride	85-94	prolactin	Oryctolagus cuniculus	7-16
6424745-4	1983	The Ca2+ channel blocking agent D600 (6 micrograms/ml) decreases the stimulatory effect of prolactin on casein secretion, but does not interfere in the stimulatory effect of arachidonic acid.	Gallopamil	32-36	prolactin	Oryctolagus cuniculus	91-100
6424745-5	1983	The calmodulin inhibitor trifluoperazine (100 microM) inhibits stimulation of casein secretion by both prolactin and arachidonic acid.	Trifluoperazine	25-40	prolactin	Oryctolagus cuniculus	103-112
6424745-7	1983	However, stimulation by prolactin, but not stimulation by arachidonic acid, requires Ca2+ movement through calcium pathways.	Calcium	107-114	prolactin	Oryctolagus cuniculus	24-33
6306227-2	1983	Ouabain-sensitive 86Rb+ uptake in slices of lactating rabbit mammary gland significantly increased after 20 min or 1 hr of incubation with ovine prolactin (NIH-P-S12; 1 microgram/ml.).	Rubidium-86	18-23	prolactin	Oryctolagus cuniculus	145-154
7139336-0	1982	Ovine prolactin administration modifies [3H]spiperone binding to striatal membranes of rabbits.	Tritium	41-43	prolactin	Oryctolagus cuniculus	6-15
7139336-0	1982	Ovine prolactin administration modifies [3H]spiperone binding to striatal membranes of rabbits.	Spiperone	44-53	prolactin	Oryctolagus cuniculus	6-15
6763497-5	1982	These prolactin effects are amplified by glucocorticoids which are not per se inducers and they are inhibited by progesterone.	Progesterone	113-125	prolactin	Oryctolagus cuniculus	6-15
7086239-5	1982	These findings suggest that PRL activates TG synthesis in liver and consequently increases serum TG levels.	Triglycerides	97-99	prolactin	Oryctolagus cuniculus	28-31
7086239-6	1982	The serum levels of TG, free fatty acid, cholesterol and glucose significantly rose in rabbits" fetuses after the administration of o-PRL intraperitoneally.	Glucose	57-64	prolactin	Oryctolagus cuniculus	134-137
7238502-7	1981	In the absence of prolactin (a situation obtained by injecting simultaneously CB 154, a drug which inhibits pituitary prolactin secretion) glucocorticoids exhibit no effect.	Bromocriptine	78-84	prolactin	Oryctolagus cuniculus	118-127
7086239-3	1982	Serum TG levels in non-pregnant adult rabbits were elevated in feeded states by the administration of o-PRL.	Triglycerides	6-8	prolactin	Oryctolagus cuniculus	104-107
7086239-4	1982	Marked changes were not observed in the activity of plasma lipoprotein lipase in rabbits by the administration of o-PRL, but in in vitro experiments, the up-take of 14C-acetate into lipid fraction of rabbit liver slice significantly increased by the addition of o-PRL.	14c-acetate	165-176	prolactin	Oryctolagus cuniculus	116-119
7086239-4	1982	Marked changes were not observed in the activity of plasma lipoprotein lipase in rabbits by the administration of o-PRL, but in in vitro experiments, the up-take of 14C-acetate into lipid fraction of rabbit liver slice significantly increased by the addition of o-PRL.	14c-acetate	165-176	prolactin	Oryctolagus cuniculus	264-267
7031659-2	1981	The incubation mixture was centrifuged and the supernatant was incubated with isolated mammary cell nuclei from lactating rabbits treated for 4 days by bromocryptin to antagonize prolactin and to deinduce casein gene transcription.	Bromocriptine	152-164	prolactin	Oryctolagus cuniculus	179-188
7264523-11	1981	When pseudopregnancy was induced with injection of an ovulating dose of LH, plasma prolactin rose in a similar manner as during early gestation or mating-induced pseudopregnancy.	Luteinizing Hormone	72-74	prolactin	Oryctolagus cuniculus	83-92
7264523-13	1981	The secretion of prolactin during gestation seems to be controlled entirely by ovarian steroids, probably progesterone.	Steroids	87-95	prolactin	Oryctolagus cuniculus	17-26
7264523-13	1981	The secretion of prolactin during gestation seems to be controlled entirely by ovarian steroids, probably progesterone.	Progesterone	106-118	prolactin	Oryctolagus cuniculus	17-26
6263136-3	1981	Increased saturated phosphatidylcholine (SPC) synthesis without an increase in synthesis of total PC, and increased SPC/PC, was observed after exposure to Sigma prolactin.	saturated phosphatidylcholine	10-39	prolactin	Oryctolagus cuniculus	161-170
6263136-3	1981	Increased saturated phosphatidylcholine (SPC) synthesis without an increase in synthesis of total PC, and increased SPC/PC, was observed after exposure to Sigma prolactin.	spc	41-44	prolactin	Oryctolagus cuniculus	161-170
6263136-3	1981	Increased saturated phosphatidylcholine (SPC) synthesis without an increase in synthesis of total PC, and increased SPC/PC, was observed after exposure to Sigma prolactin.	Phosphatidylcholines	42-44	prolactin	Oryctolagus cuniculus	161-170
515010-0	1979	Prolactin receptors in organ culture of rabbit mammary gland: effect of cycloheximide and prolactin.	Cycloheximide	72-85	prolactin	Oryctolagus cuniculus	0-9
6773590-0	1980	[Effect of indomethacin on the lactogenic action of prolactin].	Indomethacin	11-23	prolactin	Oryctolagus cuniculus	52-61
6773590-1	1980	The action of indomethacin on the lactogenic activity of prolactin has been evaluated usind the technique of rabbit mammary gland organ culture.	Indomethacin	14-26	prolactin	Oryctolagus cuniculus	57-66
6296934-2	1980	We have shown here that, after a single IV injection of PRL to lactating rabbits, total prolactin-receptor levels (measured after in vitro desaturation of injected prolactin by a MgCl2 treatment of the membranes) decreased from 41.6 to 18.4 p. 100 (specific binding) in 6 hrs.	Magnesium Chloride	179-184	prolactin	Oryctolagus cuniculus	88-97
6296934-3	1980	The same results were obtained in organ-culture of the rabbit mammary gland in the presence of prolactin; in addition, the down-regulation of prolactin receptors could be counteracted by lysosomotropic agents (chloroquine NH4Cl) in vitro.	Chloroquine	210-221	prolactin	Oryctolagus cuniculus	95-104
6296934-3	1980	The same results were obtained in organ-culture of the rabbit mammary gland in the presence of prolactin; in addition, the down-regulation of prolactin receptors could be counteracted by lysosomotropic agents (chloroquine NH4Cl) in vitro.	Chloroquine	210-221	prolactin	Oryctolagus cuniculus	142-151
6296934-3	1980	The same results were obtained in organ-culture of the rabbit mammary gland in the presence of prolactin; in addition, the down-regulation of prolactin receptors could be counteracted by lysosomotropic agents (chloroquine NH4Cl) in vitro.	Ammonium Chloride	222-227	prolactin	Oryctolagus cuniculus	95-104
6296934-3	1980	The same results were obtained in organ-culture of the rabbit mammary gland in the presence of prolactin; in addition, the down-regulation of prolactin receptors could be counteracted by lysosomotropic agents (chloroquine NH4Cl) in vitro.	Ammonium Chloride	222-227	prolactin	Oryctolagus cuniculus	142-151
118820-3	1979	Converse-y, colchicine totally blocked the lactogenic action of prolactin without altering the down-regulation of the receptor.	Colchicine	12-22	prolactin	Oryctolagus cuniculus	64-73
7026234-2	1981	Colchicine, which has been shown to block the prolactin signal, totally prevented the accumulation of beta-casein mRNA, when injected with the hormone.	Colchicine	0-10	prolactin	Oryctolagus cuniculus	46-55
7026234-4	1981	The effect of prolactin injected with colchicine on casein synthesis was totally abrogated by progesterone administered simultaneously and it was essentially unmodified by glucocorticoids.	Colchicine	38-48	prolactin	Oryctolagus cuniculus	14-23
7026234-4	1981	The effect of prolactin injected with colchicine on casein synthesis was totally abrogated by progesterone administered simultaneously and it was essentially unmodified by glucocorticoids.	Progesterone	94-106	prolactin	Oryctolagus cuniculus	14-23
6161010-3	1980	Five microtubule disrupting drugs, colchicine, colcemid, vinblastin, podophyllotoxin and nocodazole inhibited the induction of casein and DNA synthesis by prolactin whereas two inactive analogues, trimethylcolchicinic acid and lumicolchicine had no effect.	Colchicine	35-45	prolactin	Oryctolagus cuniculus	155-164
6161010-3	1980	Five microtubule disrupting drugs, colchicine, colcemid, vinblastin, podophyllotoxin and nocodazole inhibited the induction of casein and DNA synthesis by prolactin whereas two inactive analogues, trimethylcolchicinic acid and lumicolchicine had no effect.	Vinblastine	57-67	prolactin	Oryctolagus cuniculus	155-164
6161010-3	1980	Five microtubule disrupting drugs, colchicine, colcemid, vinblastin, podophyllotoxin and nocodazole inhibited the induction of casein and DNA synthesis by prolactin whereas two inactive analogues, trimethylcolchicinic acid and lumicolchicine had no effect.	Podophyllotoxin	69-84	prolactin	Oryctolagus cuniculus	155-164
6161010-3	1980	Five microtubule disrupting drugs, colchicine, colcemid, vinblastin, podophyllotoxin and nocodazole inhibited the induction of casein and DNA synthesis by prolactin whereas two inactive analogues, trimethylcolchicinic acid and lumicolchicine had no effect.	Nocodazole	89-99	prolactin	Oryctolagus cuniculus	155-164
6161010-3	1980	Five microtubule disrupting drugs, colchicine, colcemid, vinblastin, podophyllotoxin and nocodazole inhibited the induction of casein and DNA synthesis by prolactin whereas two inactive analogues, trimethylcolchicinic acid and lumicolchicine had no effect.	trimethylcolchicinic acid	197-222	prolactin	Oryctolagus cuniculus	155-164
6161010-3	1980	Five microtubule disrupting drugs, colchicine, colcemid, vinblastin, podophyllotoxin and nocodazole inhibited the induction of casein and DNA synthesis by prolactin whereas two inactive analogues, trimethylcolchicinic acid and lumicolchicine had no effect.	lumicolchicine	227-241	prolactin	Oryctolagus cuniculus	155-164
7374766-6	1980	However, high levels of prolactin decreased progesterone production.	Progesterone	44-56	prolactin	Oryctolagus cuniculus	24-33
6247227-0	1980	Effects of lysosomotropic agents, cytochalasin B and colchicine on the "down-regulation" of prolactin receptors in mammary gland explants.	Cytochalasin B	34-48	prolactin	Oryctolagus cuniculus	92-101
6247227-0	1980	Effects of lysosomotropic agents, cytochalasin B and colchicine on the "down-regulation" of prolactin receptors in mammary gland explants.	Colchicine	53-63	prolactin	Oryctolagus cuniculus	92-101
6247227-3	1980	In the present experiments, lysosomotropic agents, chloroquine, ammonium chloride and methylamine, in the presence of prolactin are capable of almost completely preventing this down-regulation.	Chloroquine	51-62	prolactin	Oryctolagus cuniculus	118-127
6247227-3	1980	In the present experiments, lysosomotropic agents, chloroquine, ammonium chloride and methylamine, in the presence of prolactin are capable of almost completely preventing this down-regulation.	Ammonium Chloride	64-81	prolactin	Oryctolagus cuniculus	118-127
6247227-3	1980	In the present experiments, lysosomotropic agents, chloroquine, ammonium chloride and methylamine, in the presence of prolactin are capable of almost completely preventing this down-regulation.	methylamine	86-97	prolactin	Oryctolagus cuniculus	118-127
118820-4	1979	Cytochalasin B inhibited only partly the lactogenic action of prolactin while it has no effect on the down-regulation of the receptor.	Cytochalasin B	0-14	prolactin	Oryctolagus cuniculus	62-71
105878-5	1978	Gel filtration of rabbit pituitary PRL and rabbit serum on Sephadex G-100 revealed coincident peaks of activity measured by RIA and by PRL radioreceptor assay.	sephadex	59-73	prolactin	Oryctolagus cuniculus	35-38
567478-11	1978	By contrast, the stimulatory effect of prolactin on protein synthesis was diminished and the induction of medium-chain fatty acid synthesis by prolactin was almost abolished.	medium-chain fatty acid	106-129	prolactin	Oryctolagus cuniculus	143-152
105878-5	1978	Gel filtration of rabbit pituitary PRL and rabbit serum on Sephadex G-100 revealed coincident peaks of activity measured by RIA and by PRL radioreceptor assay.	sephadex	59-73	prolactin	Oryctolagus cuniculus	135-138
105878-7	1978	Serum PRL levels increased after the injection of both TRH and chlorpromazine and were reduced by CB154 (Bromocriptine).	Chlorpromazine	63-77	prolactin	Oryctolagus cuniculus	6-9
105878-7	1978	Serum PRL levels increased after the injection of both TRH and chlorpromazine and were reduced by CB154 (Bromocriptine).	Bromocriptine	98-103	prolactin	Oryctolagus cuniculus	6-9
105878-7	1978	Serum PRL levels increased after the injection of both TRH and chlorpromazine and were reduced by CB154 (Bromocriptine).	Bromocriptine	105-118	prolactin	Oryctolagus cuniculus	6-9
633132-0	1978	Sodium and water metabolism under the influence of prolactin, aldosterone, and antidiuretic hormone.	Sodium	0-6	prolactin	Oryctolagus cuniculus	51-60
630590-4	1978	When prolactin is added immediately after a pulse labelling of proteins (3 min with 3H-L-leucine), the amount of labelled caseins secreted during one hour is significantly increased.	Leucine	84-96	prolactin	Oryctolagus cuniculus	5-14
633132-0	1978	Sodium and water metabolism under the influence of prolactin, aldosterone, and antidiuretic hormone.	Water	11-16	prolactin	Oryctolagus cuniculus	51-60
633132-13	1978	Prolactin (200 i.u./day) caused a reduction in urine volume and in renal sodium excretion and since there were no compensatory changes in water and sodium intake, this led to substantial accumulation of both water and sodium.	Sodium	73-79	prolactin	Oryctolagus cuniculus	0-9
633132-13	1978	Prolactin (200 i.u./day) caused a reduction in urine volume and in renal sodium excretion and since there were no compensatory changes in water and sodium intake, this led to substantial accumulation of both water and sodium.	Water	208-213	prolactin	Oryctolagus cuniculus	0-9
4430400-0	1974	The effects of prolactin on the renal excretion of water, sodium, potassium and calcium in the rabbit.	Water	51-56	prolactin	Oryctolagus cuniculus	15-24
576871-0	1977	The effect of prolactin on the lecithin content of fetal rabbit lung.	Lecithins	31-39	prolactin	Oryctolagus cuniculus	14-23
576871-4	1977	Analysis of lung tissue composition yielded the following results: (a) the prolactin-treated group of fetuses showed 40% higher total lung phospholipid content (17.0 +/- 0.8 micronmol/g) than the control group (12.2 +/- 0.5 micronmol/g); (b) the prolactin-treated group had a 67% higher lung lecithin content (8.7 +/- 0.8 micronmol/g) than the control group (5.2 +/- 0.4 micronmol/g); (c) dipalmitoyllecithin accounted for 67% of total lung lecithin in the prolactin-treated group and 44% in the control group.	Phospholipids	139-151	prolactin	Oryctolagus cuniculus	75-84
576871-4	1977	Analysis of lung tissue composition yielded the following results: (a) the prolactin-treated group of fetuses showed 40% higher total lung phospholipid content (17.0 +/- 0.8 micronmol/g) than the control group (12.2 +/- 0.5 micronmol/g); (b) the prolactin-treated group had a 67% higher lung lecithin content (8.7 +/- 0.8 micronmol/g) than the control group (5.2 +/- 0.4 micronmol/g); (c) dipalmitoyllecithin accounted for 67% of total lung lecithin in the prolactin-treated group and 44% in the control group.	Lecithins	292-300	prolactin	Oryctolagus cuniculus	75-84
576871-4	1977	Analysis of lung tissue composition yielded the following results: (a) the prolactin-treated group of fetuses showed 40% higher total lung phospholipid content (17.0 +/- 0.8 micronmol/g) than the control group (12.2 +/- 0.5 micronmol/g); (b) the prolactin-treated group had a 67% higher lung lecithin content (8.7 +/- 0.8 micronmol/g) than the control group (5.2 +/- 0.4 micronmol/g); (c) dipalmitoyllecithin accounted for 67% of total lung lecithin in the prolactin-treated group and 44% in the control group.	1,2-Dipalmitoylphosphatidylcholine	389-408	prolactin	Oryctolagus cuniculus	75-84
59378-3	1976	The binding of both fluorescein labeled prolactin and estradiol to a variety of whole cells or to microsomal fragments has been observed by fluorescence microscopy.	Fluorescein	20-31	prolactin	Oryctolagus cuniculus	40-49
1255073-0	1976	Proceedings: Water and sodium accumulation in rabbits after administration of prolactin.	Water	13-18	prolactin	Oryctolagus cuniculus	78-87
1255073-0	1976	Proceedings: Water and sodium accumulation in rabbits after administration of prolactin.	Sodium	23-29	prolactin	Oryctolagus cuniculus	78-87
1214226-5	1975	Prolactin treatment increased milk [lactose] and [K] and decreased [Na] and [Cl] in late lactation, and thus reversed the normal changes in late lactation, but had no significant effect in established lactation.	Lactose	36-43	prolactin	Oryctolagus cuniculus	0-9
1214226-7	1975	[14C]sucrose movements from blood to milk were significantly decreased to levels characteristic of established lactation, following prolactin treatment in late lactation.	Carbon-14	1-4	prolactin	Oryctolagus cuniculus	132-141
1214226-7	1975	[14C]sucrose movements from blood to milk were significantly decreased to levels characteristic of established lactation, following prolactin treatment in late lactation.	Sucrose	5-12	prolactin	Oryctolagus cuniculus	132-141
1214226-11	1975	It is suggested that prolactin in some way affects paracellular movements of ions and small molecules like lactose across the mammary epithelium, and that this mechanism is responsible for the changes in the composition of the aqueous phase of milk.	Lactose	107-114	prolactin	Oryctolagus cuniculus	21-30
1193000-2	1975	The addition of ovine prolactin (NIH-P-S-10) to the perfusate in a concentration of 50 ng/ml produced rapid increases in both the amplitude and rate of contraction in 33 adult male hearts studied in winter.	nih-p-s-10	33-43	prolactin	Oryctolagus cuniculus	22-31
1193000-4	1975	Pretreatment for 10 days with 2.5 mg/day testosterone propionate led to minimal inotropic but not chronotropic responses in 2 out of 4 prepubertal males and 2 out of 4 adult females to prolactin.	Testosterone Propionate	41-64	prolactin	Oryctolagus cuniculus	185-194
1193000-5	1975	Clear responses to prolactin were seen in 5 adult males pretreated with reserpine.	Reserpine	72-81	prolactin	Oryctolagus cuniculus	19-28
1193000-6	1975	Propanolol consistently reversed both the inotropic and chronotropic actions of prolactin.	Propranolol	0-10	prolactin	Oryctolagus cuniculus	80-89
4430400-0	1974	The effects of prolactin on the renal excretion of water, sodium, potassium and calcium in the rabbit.	Calcium	80-87	prolactin	Oryctolagus cuniculus	15-24
4673877-0	1972	The localization of prolactin labelled with radioactive iodine in rabbit mammary tissue.	radioactive iodine	44-62	prolactin	Oryctolagus cuniculus	20-29
18762820-2	2008	Fragments of ewe hypophysis and lactating rabbit mammary gland incubated in vitro in the presence of pectic acid secreted more PRL and caseins compared to the controls.	polygalacturonic acid	101-112	prolactin	Oryctolagus cuniculus	127-130
30177141-9	2018	The area under the curve (AUC0-2h) calculated for GGT, LDH, and lactates was significantly higher after perfusion with the HTK than with HTK with the addition of PRL.	Lactates	64-72	prolactin	Oryctolagus cuniculus	162-165
17164431-6	2007	Cells secreted PRL consititutively and at increased rates in response to CCh.	Carbachol	73-76	prolactin	Oryctolagus cuniculus	15-18
17904551-13	2007	Endocytosed PRL was stored in intact form and released in response to stimulation with carbachol.	Carbachol	87-96	prolactin	Oryctolagus cuniculus	12-15
10704922-2	2000	Recently, we have shown that under conditions of lipid deprivation, perturbed prolactin traffic paralleled changes in the membrane phospholipid composition and in the cytosol versus membrane distribution of annexin VI (Ollivier-Bousquet et al., 1997).	Phospholipids	131-143	prolactin	Oryctolagus cuniculus	78-87
11012839-2	2000	Bromocriptine (1 mg/kg/day), given to intact mothers across postpartum days 1-5, decreased serum concentrations of prolactin to undetectable levels, reduced crouching, and increased time inside the nest.	Bromocriptine	0-13	prolactin	Oryctolagus cuniculus	115-124
15649326-9	2005	A maximum in median eminence 5HT concentration occurred at 21:00 h whereas adenohypophysial 5HT peaked at 13:00 h. Median eminence 5HT concentration and circulating prolactin correlated inversely.	Serotonin	92-95	prolactin	Oryctolagus cuniculus	165-174
15649326-9	2005	A maximum in median eminence 5HT concentration occurred at 21:00 h whereas adenohypophysial 5HT peaked at 13:00 h. Median eminence 5HT concentration and circulating prolactin correlated inversely.	Serotonin	92-95	prolactin	Oryctolagus cuniculus	165-174
15649326-11	2005	Median eminence GABA concentration correlated inversely with circulating prolactin.	gamma-Aminobutyric Acid	16-20	prolactin	Oryctolagus cuniculus	73-82
15649326-13	2005	In the adenohypophysis, minimal taurine levels coincided with the major plasma prolactin peak (at 01:00 h).	Taurine	32-39	prolactin	Oryctolagus cuniculus	79-88
15667449-0	2004	Intracerebroventricular injections of prolactin counteract the antagonistic effect of bromocriptine on rabbit maternal behaviour.	Bromocriptine	86-99	prolactin	Oryctolagus cuniculus	38-47
15794342-10	2004	It was found that administration of prolactin during 2 h of perfusion led to a significant decrease of ALT, ALP and lactate concentrations in the eluate.	Lactic Acid	116-123	prolactin	Oryctolagus cuniculus	36-45
15794342-11	2004	In addition, increase of calcium concentration in the liver was significantly lower with the prolactin group.	Calcium	25-32	prolactin	Oryctolagus cuniculus	93-102
12198246-12	2002	Site-directed mutagenesis and transient transfection assays showed the RUSH motif mediates the ability of PRL to augment progesterone-dependent uteroglobin transcription.	Progesterone	121-133	prolactin	Oryctolagus cuniculus	106-109
11804403-5	2001	The results showed that the vaginal ring of bromocriptine mesilate significantly decreased the plasma prolactin level of the test group (P < 0.001-0.05) compared with the control and placebo groups.	Bromocriptine	44-57	prolactin	Oryctolagus cuniculus	102-111
11804403-6	2001	It was concluded that bromocriptine mesilate was effectively absorbed from rabbit vagina and that this controlled release intravaginal ring preparation of bromocriptine mesilate was effective in decreasing the plasma prolactin level in rabbits for ten days.	Bromocriptine	22-44	prolactin	Oryctolagus cuniculus	217-226
11804403-6	2001	It was concluded that bromocriptine mesilate was effectively absorbed from rabbit vagina and that this controlled release intravaginal ring preparation of bromocriptine mesilate was effective in decreasing the plasma prolactin level in rabbits for ten days.	Bromocriptine	155-177	prolactin	Oryctolagus cuniculus	217-226
8986134-11	1996	Staurosporine, but not GF 109203X, prevented the induction of the casein gene by prolactin.	Staurosporine	0-13	prolactin	Oryctolagus cuniculus	81-90
9718072-0	1998	Effect of naloxone on serum prolactin levels in adult male rabbits.	Naloxone	10-18	prolactin	Oryctolagus cuniculus	28-37
9718072-1	1998	In order to clarify the possible physiological role of endogenous opioid peptides (EOP), we studied the effect of low doses of naloxone (specific opiate antagonist) on plasma prolactin levels in male rabbits.	Naloxone	127-135	prolactin	Oryctolagus cuniculus	175-184
9305538-3	1997	Following SDS-PAGE, this factor displayed an apparent Mr of 17 kDa, which is different from the Mr of most known endogenous factors having an inhibiting activity on pituitary prolactin secretion, suggesting that this may be a yet-to-be identified novel molecule.	Sodium Dodecyl Sulfate	10-13	prolactin	Oryctolagus cuniculus	175-184
8953467-7	1996	A significant increase in PRL plasma levels was observed on day 9 in does given EB plus 2 mg P/day and at two days following P withdrawal in does given EB plus 10 mg P/day.	estradiol 3-benzoate	80-82	prolactin	Oryctolagus cuniculus	26-29
8953467-7	1996	A significant increase in PRL plasma levels was observed on day 9 in does given EB plus 2 mg P/day and at two days following P withdrawal in does given EB plus 10 mg P/day.	estradiol 3-benzoate	152-154	prolactin	Oryctolagus cuniculus	26-29
8953467-8	1996	When such ovx EB/P-treated does were given bromocriptine to block PRL release (1 or 3 mg/Kg/day, from days 11 to 21) the expression of digging was unmodified.	Bromocriptine	43-56	prolactin	Oryctolagus cuniculus	66-69
8953467-10	1996	The addition of ovine PRL to ovx EB/P-treated does given bromocriptine reduced the expression of digging, did not restore straw-carrying or hair-pulling, and provoked a sharp decline in food intake.	Bromocriptine	57-70	prolactin	Oryctolagus cuniculus	22-25
9568361-2	1996	In vivo, a single injection of 1 mg of ovine prolactin induces increased plasma glycerol and nonesterified fatty acids concentrations within 30 min (P < 0.01).	Glycerol	80-88	prolactin	Oryctolagus cuniculus	45-54
9568361-2	1996	In vivo, a single injection of 1 mg of ovine prolactin induces increased plasma glycerol and nonesterified fatty acids concentrations within 30 min (P < 0.01).	Fatty Acids, Nonesterified	93-118	prolactin	Oryctolagus cuniculus	45-54
1915421-11	1991	These results show that intracellular transport of prolactin and secretagogue effect of the hormone does not proceed at 25 degrees C. However, secretory mechanisms of the cell are always able to be stimulated by exogenous arachidonic acid at this temperature.	Arachidonic Acid	222-238	prolactin	Oryctolagus cuniculus	51-60
8016168-8	1994	We have also analyzed tyrosine phosphorylation induced by PRL.	Tyrosine	22-30	prolactin	Oryctolagus cuniculus	58-61
8016168-9	1994	In CHO cells stably transfected with PRL receptor cDNA, PRL induced a very rapid and transient tyrosine phosphorylation of a 100-kDa protein which is most probably the PRL receptor.	Tyrosine	95-103	prolactin	Oryctolagus cuniculus	37-40
8016168-9	1994	In CHO cells stably transfected with PRL receptor cDNA, PRL induced a very rapid and transient tyrosine phosphorylation of a 100-kDa protein which is most probably the PRL receptor.	Tyrosine	95-103	prolactin	Oryctolagus cuniculus	56-59
8016168-9	1994	In CHO cells stably transfected with PRL receptor cDNA, PRL induced a very rapid and transient tyrosine phosphorylation of a 100-kDa protein which is most probably the PRL receptor.	Tyrosine	95-103	prolactin	Oryctolagus cuniculus	56-59
8016168-11	1994	Whereas tyrosine kinase inhibitors genistein and lavendustin were without effect, PRL stimulation of milk protein gene promoters was partially inhibited by 2 microM herbimycin in CHO cells co-transfected with PRL receptor cDNA and the beta lactoglobulin CAT construct.	herbimycin	165-175	prolactin	Oryctolagus cuniculus	82-85
8016168-11	1994	Whereas tyrosine kinase inhibitors genistein and lavendustin were without effect, PRL stimulation of milk protein gene promoters was partially inhibited by 2 microM herbimycin in CHO cells co-transfected with PRL receptor cDNA and the beta lactoglobulin CAT construct.	herbimycin	165-175	prolactin	Oryctolagus cuniculus	209-212
16727287-0	1993	Effects of naloxone, metaclopramide and domperidone on plasma levels of prolactin and LH following suckling in the female rabbit.	Domperidone	40-51	prolactin	Oryctolagus cuniculus	72-81
16727287-4	1993	The increase in prolactin concentration was similar in does given saline and naloxone, but it was significantly enhanced in does given metaclopramide; with domperidone the increase was intermediate and not significantly different from that following treatment with saline.	Sodium Chloride	66-72	prolactin	Oryctolagus cuniculus	16-25
16727287-4	1993	The increase in prolactin concentration was similar in does given saline and naloxone, but it was significantly enhanced in does given metaclopramide; with domperidone the increase was intermediate and not significantly different from that following treatment with saline.	Naloxone	77-85	prolactin	Oryctolagus cuniculus	16-25
16727287-4	1993	The increase in prolactin concentration was similar in does given saline and naloxone, but it was significantly enhanced in does given metaclopramide; with domperidone the increase was intermediate and not significantly different from that following treatment with saline.	Metoclopramide	135-149	prolactin	Oryctolagus cuniculus	16-25
1292481-1	1992	The secretagogue effect of prolactin (PRL) on casein release by epithelial mammary cells has been previously related to stimulation of the phospholipase A2-arachidonic acid cascade.	Arachidonic Acid	156-172	prolactin	Oryctolagus cuniculus	27-36
1292481-1	1992	The secretagogue effect of prolactin (PRL) on casein release by epithelial mammary cells has been previously related to stimulation of the phospholipase A2-arachidonic acid cascade.	Arachidonic Acid	156-172	prolactin	Oryctolagus cuniculus	38-41
1292481-3	1992	Phorbol ester (20 nm TPA and 1-oleoyl-2-acetyl-sn-glycerol (10 microM (OAG) stimulated newly synthesized casein secretion and potentiated the PRL secretatogue effect.	Phorbol Esters	0-13	prolactin	Oryctolagus cuniculus	142-145
1292481-3	1992	Phorbol ester (20 nm TPA and 1-oleoyl-2-acetyl-sn-glycerol (10 microM (OAG) stimulated newly synthesized casein secretion and potentiated the PRL secretatogue effect.	Tetradecanoylphorbol Acetate	21-24	prolactin	Oryctolagus cuniculus	142-145
1292481-3	1992	Phorbol ester (20 nm TPA and 1-oleoyl-2-acetyl-sn-glycerol (10 microM (OAG) stimulated newly synthesized casein secretion and potentiated the PRL secretatogue effect.	1-oleoyl-2-acetylglycerol	29-58	prolactin	Oryctolagus cuniculus	142-145
1292481-3	1992	Phorbol ester (20 nm TPA and 1-oleoyl-2-acetyl-sn-glycerol (10 microM (OAG) stimulated newly synthesized casein secretion and potentiated the PRL secretatogue effect.	1-oleoyl-2-acetylglycerol	71-74	prolactin	Oryctolagus cuniculus	142-145
7799305-0	1994	Effects of anoestrus and bromocryptine treatment on the expression of prolactin and LH receptors in the rabbit ovary during lactation.	Bromocriptine	25-38	prolactin	Oryctolagus cuniculus	70-79
2294009-5	1990	Sodium dodecyl sulfate treatment revealed inhibition of connective tissue disruption at the apex of the follicle wall in PRL-treated ovaries.	Sodium Dodecyl Sulfate	0-22	prolactin	Oryctolagus cuniculus	121-124
1995853-6	1991	From this survey it was apparent that uteroglobin secretion could be induced by exogenous oestradiol and progesterone in rabbits treated as early as 14 days of age, and that the added supplementation of prolactin enhanced the response to the ovarian steroids.	Estradiol	90-100	prolactin	Oryctolagus cuniculus	203-212
1995853-6	1991	From this survey it was apparent that uteroglobin secretion could be induced by exogenous oestradiol and progesterone in rabbits treated as early as 14 days of age, and that the added supplementation of prolactin enhanced the response to the ovarian steroids.	Progesterone	105-117	prolactin	Oryctolagus cuniculus	203-212
1995853-6	1991	From this survey it was apparent that uteroglobin secretion could be induced by exogenous oestradiol and progesterone in rabbits treated as early as 14 days of age, and that the added supplementation of prolactin enhanced the response to the ovarian steroids.	Steroids	250-258	prolactin	Oryctolagus cuniculus	203-212
1995853-8	1991	Prolactin modified the response of the juvenile rabbit uterus to oestradiol + progesterone for all parameters tested.	Estradiol	65-75	prolactin	Oryctolagus cuniculus	0-9
1995853-8	1991	Prolactin modified the response of the juvenile rabbit uterus to oestradiol + progesterone for all parameters tested.	Progesterone	78-90	prolactin	Oryctolagus cuniculus	0-9
2390059-5	1990	The delta S++ for dissociation was negative, and the enthalpy of activation for dissociation was about 20.3 kJ.mol-1 larger than that for association, indicating that the PRL-receptor complex is further stabilized by contributions of hydrogen bonds and van der Waals contacts after the initial interaction.	delta s++	4-13	prolactin	Oryctolagus cuniculus	171-174
2390059-5	1990	The delta S++ for dissociation was negative, and the enthalpy of activation for dissociation was about 20.3 kJ.mol-1 larger than that for association, indicating that the PRL-receptor complex is further stabilized by contributions of hydrogen bonds and van der Waals contacts after the initial interaction.	Hydrogen	234-242	prolactin	Oryctolagus cuniculus	171-174
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Sodium Chloride	128-132	prolactin	Oryctolagus cuniculus	21-30
2295424-1	1990	A highly purified prolactin (PRL) was obtained from pituitary glands of newts, Cynops pyrrhogaster, by extraction of acetone-dried powder with acid acetone and high-performance liquid chromatography (HPLC) on Mono-Q (anion exchange), Superose-12 (gel filtration), and TSK-gel ODS-120T (reverse-phase) columns with a yield of 4.5 mg per 325 mg of protein starting material.	Acetone	117-124	prolactin	Oryctolagus cuniculus	29-32
2295424-1	1990	A highly purified prolactin (PRL) was obtained from pituitary glands of newts, Cynops pyrrhogaster, by extraction of acetone-dried powder with acid acetone and high-performance liquid chromatography (HPLC) on Mono-Q (anion exchange), Superose-12 (gel filtration), and TSK-gel ODS-120T (reverse-phase) columns with a yield of 4.5 mg per 325 mg of protein starting material.	acid acetone	143-155	prolactin	Oryctolagus cuniculus	29-32
2295424-1	1990	A highly purified prolactin (PRL) was obtained from pituitary glands of newts, Cynops pyrrhogaster, by extraction of acetone-dried powder with acid acetone and high-performance liquid chromatography (HPLC) on Mono-Q (anion exchange), Superose-12 (gel filtration), and TSK-gel ODS-120T (reverse-phase) columns with a yield of 4.5 mg per 325 mg of protein starting material.	Mono Q	209-215	prolactin	Oryctolagus cuniculus	29-32
2295424-3	1990	Newt PRL thus obtained has a molecular weight of 23,000 as determined by SDS-PAGE.	Sodium Dodecyl Sulfate	73-76	prolactin	Oryctolagus cuniculus	5-8
2299270-4	1990	This rise of prolactin at the end of pregnancy was not due to mating stimuli and occurred at a time when progesterone levels were still high (159 nmol/l).	Progesterone	105-117	prolactin	Oryctolagus cuniculus	13-22
2299270-5	1990	The injection of a slow-release preparation of bromocriptine (5 mg s.c.), which reduces prolactin secretion at the end of pregnancy, did not impair parturition.	Bromocriptine	47-60	prolactin	Oryctolagus cuniculus	88-97
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Sodium Chloride	128-132	prolactin	Oryctolagus cuniculus	32-35
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Potassium Chloride	134-137	prolactin	Oryctolagus cuniculus	21-30
2620667-1	1989	The influence of NaCl, KCl, CaCl2, and MgCl2 on the binding of prolactin (PRL) to its receptor was investigated.	Magnesium Chloride	39-44	prolactin	Oryctolagus cuniculus	63-72
2620667-1	1989	The influence of NaCl, KCl, CaCl2, and MgCl2 on the binding of prolactin (PRL) to its receptor was investigated.	Magnesium Chloride	39-44	prolactin	Oryctolagus cuniculus	74-77
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Potassium Chloride	134-137	prolactin	Oryctolagus cuniculus	32-35
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Calcium Chloride	139-144	prolactin	Oryctolagus cuniculus	21-30
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Calcium Chloride	139-144	prolactin	Oryctolagus cuniculus	32-35
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Magnesium Chloride	146-151	prolactin	Oryctolagus cuniculus	21-30
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Magnesium Chloride	146-151	prolactin	Oryctolagus cuniculus	32-35
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Glycerol	153-161	prolactin	Oryctolagus cuniculus	21-30
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Glucose	163-170	prolactin	Oryctolagus cuniculus	21-30
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Glucose	163-170	prolactin	Oryctolagus cuniculus	32-35
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Sucrose	172-179	prolactin	Oryctolagus cuniculus	21-30
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Sucrose	172-179	prolactin	Oryctolagus cuniculus	32-35
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Urea	184-188	prolactin	Oryctolagus cuniculus	21-30
2620666-1	1989	The binding assay of prolactin (PRL) to the receptor in the rabbit mammary gland was carried out with varying concentrations of NaCl, KCl, CaCl2, MgCl2, glycerol, glucose, sucrose and urea.	Urea	184-188	prolactin	Oryctolagus cuniculus	32-35
2620666-5	1989	Among the agents examined, chaotropic salts (CaCl2 and MgCl2) inhibited the binding of PRL greatly, and were the most effective in decreasing the k+1.	Calcium Chloride	45-50	prolactin	Oryctolagus cuniculus	87-90
2620666-5	1989	Among the agents examined, chaotropic salts (CaCl2 and MgCl2) inhibited the binding of PRL greatly, and were the most effective in decreasing the k+1.	Magnesium Chloride	55-60	prolactin	Oryctolagus cuniculus	87-90
2620666-6	1989	Both hydrogen- and hydrophobic bonds are involved in the interaction between PRL and the receptor.	Hydrogen	5-13	prolactin	Oryctolagus cuniculus	77-80
2620667-1	1989	The influence of NaCl, KCl, CaCl2, and MgCl2 on the binding of prolactin (PRL) to its receptor was investigated.	Sodium Chloride	17-21	prolactin	Oryctolagus cuniculus	63-72
2620667-1	1989	The influence of NaCl, KCl, CaCl2, and MgCl2 on the binding of prolactin (PRL) to its receptor was investigated.	Sodium Chloride	17-21	prolactin	Oryctolagus cuniculus	74-77
2620667-1	1989	The influence of NaCl, KCl, CaCl2, and MgCl2 on the binding of prolactin (PRL) to its receptor was investigated.	Potassium Chloride	23-26	prolactin	Oryctolagus cuniculus	63-72
2620667-1	1989	The influence of NaCl, KCl, CaCl2, and MgCl2 on the binding of prolactin (PRL) to its receptor was investigated.	Calcium Chloride	28-33	prolactin	Oryctolagus cuniculus	63-72
2620667-1	1989	The influence of NaCl, KCl, CaCl2, and MgCl2 on the binding of prolactin (PRL) to its receptor was investigated.	Calcium Chloride	28-33	prolactin	Oryctolagus cuniculus	74-77
3184037-0	1988	Variability in the response of the rabbit uterus to progesterone as influenced by prolactin.	Progesterone	52-64	prolactin	Oryctolagus cuniculus	82-91
2792190-2	1989	The treatment of aged rabbits for 30 days with S-adenosyl-L-methionine (SAM) restored the number of PRL binding sites to levels found in the hypothalamus and substantia nigra from young animals.	S-Adenosylmethionine	47-70	prolactin	Oryctolagus cuniculus	100-103
3360296-1	1988	The binding of 125I-labeled ovine prolactin (125I-oPRL) to membranes from different brain regions of pigeon, rabbit, rat, pig, calf, horse, and ewe was studied.	Iodine-125	15-19	prolactin	Oryctolagus cuniculus	34-43
2834771-2	1988	13-[14C]AA was incorporated in all classes of lipids and PRL increased transiently the percentage of free fatty acid after 1 and 5 min.	Fatty Acids, Nonesterified	101-116	prolactin	Oryctolagus cuniculus	57-60
2834771-5	1988	Fourteen microM indomethacin inhibited PGF2 alpha and LTC4 production and PRL-stimulated casein secretion.	Indomethacin	16-28	prolactin	Oryctolagus cuniculus	74-77
2834771-6	1988	Ten microM NdgA (nordihydroguaiaretic acid) an inhibitor of lipoxygenase pathway, inhibited LTB4 and LTC4 production, increased basal level of casein secretion and inhibited PRL-stimulated casein secretion.	Masoprocol	11-15	prolactin	Oryctolagus cuniculus	174-177
2834771-6	1988	Ten microM NdgA (nordihydroguaiaretic acid) an inhibitor of lipoxygenase pathway, inhibited LTB4 and LTC4 production, increased basal level of casein secretion and inhibited PRL-stimulated casein secretion.	Masoprocol	17-42	prolactin	Oryctolagus cuniculus	174-177
2834771-7	1988	Hundred microM caffeic acid, an inhibitor of glutathione-S-transferase (GST), a class of enzymes implied in the transformation of LTA4 into LTC4, had the same effect that NDGA on basal and PRL-stimulated casein secretion.	caffeic acid	15-27	prolactin	Oryctolagus cuniculus	189-192
3184037-3	1988	Treatment with prolactin (at 1 mg/day) plus progesterone generally induced higher levels of uteroglobin production than did treatment with progesterone alone.	Progesterone	139-151	prolactin	Oryctolagus cuniculus	15-24
3614549-14	1987	We conclude that, in the adult male rabbit, PRL modulates LH pulsation.	Luteinizing Hormone	58-60	prolactin	Oryctolagus cuniculus	44-47
3669658-2	1987	The antiprogesterone and antiglucocorticoid compound RU 486 added to pregnant rabbit mammary gland explant cultures had no effect alone but significantly stimulated casein production in the presence of ovine prolactin (PRL) in a dose dependent manner.	Mifepristone	53-59	prolactin	Oryctolagus cuniculus	219-222
3669658-4	1987	When the explants were cultured for 5 days with two changes of medium, to eliminate all steroids, and hormones added afterwards, the effect of PRL was potentiated, Pg was no longer inhibitory and RU 486 had no effect, RU 486 also could inhibit the stimulatory action of glucocorticoids added to the cultures along with PRL.	Steroids	88-96	prolactin	Oryctolagus cuniculus	143-146
3618948-0	1987	[Accumulation of adenosine-5"-triphosphate by cell membranes of rabbit mammae after administration of prolactin and its possible value for hormonal signal conduction].	Adenosine Triphosphate	17-42	prolactin	Oryctolagus cuniculus	102-111
3572889-0	1987	Differences in the rabbit uterine response to progesterone as influenced by growth hormone or prolactin.	Progesterone	46-58	prolactin	Oryctolagus cuniculus	94-103
3572889-7	1987	It is concluded that the action of prolactin in the rabbit uterus is no generally somatogenic; rather, prolactin increases the concentration of progesterone receptor and thereby enhances the uterine response to progesterone.	Progesterone	144-156	prolactin	Oryctolagus cuniculus	35-44
3572889-7	1987	It is concluded that the action of prolactin in the rabbit uterus is no generally somatogenic; rather, prolactin increases the concentration of progesterone receptor and thereby enhances the uterine response to progesterone.	Progesterone	144-156	prolactin	Oryctolagus cuniculus	103-112
2957009-0	1987	Effect of tubulozole, a new synthetic microtubule inhibitor, on the induction of casein gene expression by prolactin.	tubulazole	10-20	prolactin	Oryctolagus cuniculus	107-116
2965935-0	1987	Effects of estramustine, a new anti-microtubule drug, on the induction of casein gene expression by prolactin.	Estramustine	11-23	prolactin	Oryctolagus cuniculus	100-109
2965935-6	1987	These data also suggest that other anti-microtubule drugs such as colchicine which prevent prolactin action act through their binding to tubulin molecule unrelated to microtubule structures.	Colchicine	66-76	prolactin	Oryctolagus cuniculus	91-100
3519707-6	1986	In synergism with steroid and thyroid hormones, protein hormones of the prolactin and growth hormone family play a crucial role in stimulating the development of the mammary gland, the differentiation and function of mammary cells to secrete milk, and in the systemic adjustments in maternal metabolism in pregnancy and lactation.	Steroids	18-25	prolactin	Oryctolagus cuniculus	72-81
2430784-6	1986	Two of the IgG subclass antibodies were able to inhibit the binding of [125I] iodo-oPL to PRL receptors(s) and to GH receptor(s) in rabbit mammary gland and liver, respectively.	iodo-opl	78-86	prolactin	Oryctolagus cuniculus	90-93
3800907-2	1986	Prl receptors in the presence of 7.5 mM-Chaps were separated into two different fractions (Fr.	3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate	39-45	prolactin	Oryctolagus cuniculus	0-3
3800907-11	1986	Sucrose-gradient-centrifugation analysis showed that the Prl-receptor complexes in the presence of 5 mM-Chaps were sedimented between gamma-globulin and bovine serum albumin (5.56 +/- 0.22 S).	Sucrose	0-7	prolactin	Oryctolagus cuniculus	57-60
3800907-11	1986	Sucrose-gradient-centrifugation analysis showed that the Prl-receptor complexes in the presence of 5 mM-Chaps were sedimented between gamma-globulin and bovine serum albumin (5.56 +/- 0.22 S).	3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate	104-109	prolactin	Oryctolagus cuniculus	57-60
3800907-12	1986	As the Chaps concentration was increased to 7.5 mM, a further peak of the Prl-receptor complexes (4.01 +/- 0.23 S) appeared below ovalbumin.	3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate	7-12	prolactin	Oryctolagus cuniculus	74-77
3519707-14	1986	In maintaining lactation the greatest contrast is between ruminants, in which growth hormone is of particular importance, and other mammals, in which reduction of prolactin secretion with bromocriptine rapidly suppresses milk synthesis and secretion.	Bromocriptine	188-201	prolactin	Oryctolagus cuniculus	163-172
3945641-0	1986	Effect of various catecholamine antagonists on prolactin secretion in conscious male rabbits.	Catecholamines	18-31	prolactin	Oryctolagus cuniculus	47-56
3088690-1	1986	Phospholipase A2 and arachidonic acid mimic the stimulatory effect of prolactin on casein exocytosis.	Arachidonic Acid	21-37	prolactin	Oryctolagus cuniculus	70-79
2863827-0	1985	Effect of various catecholamine antagonists on prolactin secretion in conscious male rabbits.	Catecholamines	18-31	prolactin	Oryctolagus cuniculus	47-56
2995334-6	1985	One mAb (A917) was able to mimic the action of PRL on both casein and DNA ([3H]thymidine incorporation) synthesis, whereas the other two mAbs were without any stimulatory effect.	Tritium	76-78	prolactin	Oryctolagus cuniculus	47-50
2995334-6	1985	One mAb (A917) was able to mimic the action of PRL on both casein and DNA ([3H]thymidine incorporation) synthesis, whereas the other two mAbs were without any stimulatory effect.	Thymidine	79-88	prolactin	Oryctolagus cuniculus	47-50
3088690-2	1986	We suggest that prolactin by activating phospholipase A2, induces a release of arachidonic acid which is metabolized by a cyclooxygenase pathway leading to prostaglandins, prostacyclins and thromboxanes, a lipoxygenase pathway leading to hydroperoxides and leukotrienes and an epoxygenase pathway.	Arachidonic Acid	79-95	prolactin	Oryctolagus cuniculus	16-25
3088690-2	1986	We suggest that prolactin by activating phospholipase A2, induces a release of arachidonic acid which is metabolized by a cyclooxygenase pathway leading to prostaglandins, prostacyclins and thromboxanes, a lipoxygenase pathway leading to hydroperoxides and leukotrienes and an epoxygenase pathway.	Prostaglandins	156-170	prolactin	Oryctolagus cuniculus	16-25
3088690-2	1986	We suggest that prolactin by activating phospholipase A2, induces a release of arachidonic acid which is metabolized by a cyclooxygenase pathway leading to prostaglandins, prostacyclins and thromboxanes, a lipoxygenase pathway leading to hydroperoxides and leukotrienes and an epoxygenase pathway.	Prostaglandins I	172-185	prolactin	Oryctolagus cuniculus	16-25
3088690-2	1986	We suggest that prolactin by activating phospholipase A2, induces a release of arachidonic acid which is metabolized by a cyclooxygenase pathway leading to prostaglandins, prostacyclins and thromboxanes, a lipoxygenase pathway leading to hydroperoxides and leukotrienes and an epoxygenase pathway.	Thromboxanes	190-202	prolactin	Oryctolagus cuniculus	16-25
3088690-2	1986	We suggest that prolactin by activating phospholipase A2, induces a release of arachidonic acid which is metabolized by a cyclooxygenase pathway leading to prostaglandins, prostacyclins and thromboxanes, a lipoxygenase pathway leading to hydroperoxides and leukotrienes and an epoxygenase pathway.	Hydrogen Peroxide	238-252	prolactin	Oryctolagus cuniculus	16-25
3088690-2	1986	We suggest that prolactin by activating phospholipase A2, induces a release of arachidonic acid which is metabolized by a cyclooxygenase pathway leading to prostaglandins, prostacyclins and thromboxanes, a lipoxygenase pathway leading to hydroperoxides and leukotrienes and an epoxygenase pathway.	Leukotrienes	257-269	prolactin	Oryctolagus cuniculus	16-25
3088690-6	1986	Nor-dihydroguaiaretic acid (10 microM), an inhibitor of lipoxygenases, increased PGF2 alpha synthesis in the presence of prolactin.	Masoprocol	0-26	prolactin	Oryctolagus cuniculus	121-130
3088690-6	1986	Nor-dihydroguaiaretic acid (10 microM), an inhibitor of lipoxygenases, increased PGF2 alpha synthesis in the presence of prolactin.	Dinoprost	81-91	prolactin	Oryctolagus cuniculus	121-130
3893560-1	1985	Pregnant rabbit mammary gland explants cultured with insulin, prolactin and cortisol synthesize and secrete transferrin radiolabelled with [3H]leucine or [3H]mannose.	Tritium	140-142	prolactin	Oryctolagus cuniculus	62-71
3893560-1	1985	Pregnant rabbit mammary gland explants cultured with insulin, prolactin and cortisol synthesize and secrete transferrin radiolabelled with [3H]leucine or [3H]mannose.	Leucine	143-150	prolactin	Oryctolagus cuniculus	62-71
3893560-1	1985	Pregnant rabbit mammary gland explants cultured with insulin, prolactin and cortisol synthesize and secrete transferrin radiolabelled with [3H]leucine or [3H]mannose.	Tritium	155-157	prolactin	Oryctolagus cuniculus	62-71
3893560-1	1985	Pregnant rabbit mammary gland explants cultured with insulin, prolactin and cortisol synthesize and secrete transferrin radiolabelled with [3H]leucine or [3H]mannose.	Mannose	158-165	prolactin	Oryctolagus cuniculus	62-71