PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
35022505-0	2022	Ubiquitin-specific protease 35 (USP35) mediates cisplatin-induced apoptosis by stabilizing BIRC3 in non-small cell lung cancer.	Cisplatin	48-57	ubiquitin specific peptidase 35	Homo sapiens	0-30
34131114-5	2021	USP35 promoted the growth of ER+ breast cancer in vitro and in vivo, and reduced the sensitivity of ER+ breast cancer cells to endocrine therapies such as tamoxifen and fulvestrant.	Tamoxifen	155-164	ubiquitin specific peptidase 35	Homo sapiens	0-5
34131114-7	2021	In addition, AKT, a key effector of PI3K, phosphorylated USP35 at Serine613, which promoted USP35 nuclear translocation, ERalpha transcriptional activity, and the growth of ER+ breast cancer cells.	serine613	66-75	ubiquitin specific peptidase 35	Homo sapiens	57-62
34131114-7	2021	In addition, AKT, a key effector of PI3K, phosphorylated USP35 at Serine613, which promoted USP35 nuclear translocation, ERalpha transcriptional activity, and the growth of ER+ breast cancer cells.	serine613	66-75	ubiquitin specific peptidase 35	Homo sapiens	92-97
24001904-1	2013	The United States Pharmacopeia USP35-NF30 contains monographs for adenosine and sodium bicarbonate with imprecise and outdated color comparison assays for ammonia.	Adenosine	66-75	ubiquitin specific peptidase 35	Homo sapiens	31-36
24001904-1	2013	The United States Pharmacopeia USP35-NF30 contains monographs for adenosine and sodium bicarbonate with imprecise and outdated color comparison assays for ammonia.	Sodium Bicarbonate	80-98	ubiquitin specific peptidase 35	Homo sapiens	31-36
24001904-1	2013	The United States Pharmacopeia USP35-NF30 contains monographs for adenosine and sodium bicarbonate with imprecise and outdated color comparison assays for ammonia.	Ammonia	155-162	ubiquitin specific peptidase 35	Homo sapiens	31-36
35022505-0	2022	Ubiquitin-specific protease 35 (USP35) mediates cisplatin-induced apoptosis by stabilizing BIRC3 in non-small cell lung cancer.	Cisplatin	48-57	ubiquitin specific peptidase 35	Homo sapiens	32-37
35022505-3	2022	In this study, we investigated the role and underlying molecular mechanisms of USP35 in chemoresistance of non-small cell lung cancer (NSCLC) to cisplatin.	Cisplatin	145-154	ubiquitin specific peptidase 35	Homo sapiens	79-84
35022505-4	2022	Depletion of USP35 increased the sensitivity of NSCLC to cisplatin-induced apoptosis.	Cisplatin	57-66	ubiquitin specific peptidase 35	Homo sapiens	13-18
35022505-8	2022	USP35 alleviated cisplatin-induced cell apoptosis by regulating BIRC3 levels in NSCLC cells.	Cisplatin	17-26	ubiquitin specific peptidase 35	Homo sapiens	0-5
35022505-10	2022	Taken together, USP35 plays a vital role in resistance to cisplatin-induced cell death through the overexpression of BIRC3.	Cisplatin	58-67	ubiquitin specific peptidase 35	Homo sapiens	16-21
33931967-9	2021	USP35 overexpression did not affect tumorigenesis and ferroptosis under basal conditions, but reduced erastin/RSL3-triggered iron disturbance and ferroptosis, thereby facilitating lung cancer cell growth and tumor progression.	Iron	125-129	ubiquitin specific peptidase 35	Homo sapiens	0-5
33931967-11	2021	More importantly, we observed that USP35 knockdown sensitized lung cancer cells to cisplatin and paclitaxel chemotherapy.	Cisplatin	83-92	ubiquitin specific peptidase 35	Homo sapiens	35-40
33931967-11	2021	More importantly, we observed that USP35 knockdown sensitized lung cancer cells to cisplatin and paclitaxel chemotherapy.	Paclitaxel	97-107	ubiquitin specific peptidase 35	Homo sapiens	35-40
32678307-9	2021	Functionally, we found that knockdown of USP35 sensitizes ovarian cancer cells to the DNA-damage chemotherapeutic drug cisplatin.	Cisplatin	119-128	ubiquitin specific peptidase 35	Homo sapiens	41-46