PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
33801563-4	2021	Exposure to 100 mg/L SiO2NPs significantly upregulated expression of HSP70, TNF-alpha, IL-1beta, and IL-8 genes in the gills as compared to the control group.	sio2nps	21-28	interleukin-8	Oreochromis niloticus	101-105
33801563-5	2021	Moreover, exposure to 100 mg/L SiO2NPs significantly upregulated the expression SOD, HSP70, IL-1beta, IL-8, and TNF-alpha genes in the hepatic tissues as compared to the control group.	sio2nps	31-38	interleukin-8	Oreochromis niloticus	102-106
34203916-9	2021	The transcription of IL-1beta and IL-8 genes were also decreased by DMT exposure, while fish fed synbiotics showed upregulated levels.	decamethrin	68-71	interleukin-8	Oreochromis niloticus	34-38
33845121-7	2021	Similarly, the up-regulation of IL1, IL8, and LBP gene expressions were also detected in fish fed PAPP diets, with the maximum value was found in 10 g kg-1 PAPP fed fish.	LY 165163	98-102	interleukin-8	Oreochromis niloticus	37-40
33845121-7	2021	Similarly, the up-regulation of IL1, IL8, and LBP gene expressions were also detected in fish fed PAPP diets, with the maximum value was found in 10 g kg-1 PAPP fed fish.	LY 165163	156-160	interleukin-8	Oreochromis niloticus	37-40
32977486-9	2020	The proinflammatory cytokine (IL-8 and IFN-gamma) transcript expression was upregulated in B-MOS more than B-GLY reared groups.	Glycerol	109-112	interleukin-8	Oreochromis niloticus	30-34
31972291-6	2020	Additionally, DLM toxicity caused downregulation in antioxidant (CAT and GPx) and immune (IL-1beta and IL-8) related gene expressions, while and IFN-gamma, HSP70 and CASP3 were upregulated.	decamethrin	14-17	interleukin-8	Oreochromis niloticus	103-107
33022381-4	2021	TCE significantly (P < 0.05) ameliorated the toxic effects caused by TNP by increasing the endogenous antioxidant (CAT, SOD, and GPx) activity and decreasing the levels of serum marker enzymes (ALT, AST, ALP, and ACP), macromolecular oxidation, excessive ROS production, and pro-inflammatory cytokines (IL-1beta, IL-6, IL-8, INF-gamma, TNF-alpha, and PGE-2).	Trichloroethylene	0-3	interleukin-8	Oreochromis niloticus	319-323
31730927-10	2020	Furthermore, we also found that addition of 200 mmol/L sodium acetate mainly inhibited p38 mitogen-activated protein kinase (p38MAPK) and NF-kappaB phosphorylation to decrease the expression level of inflammation cytokines (IL-8, IL-12, TNF-alpha and IL-1beta) in the intestine.	Sodium Acetate	55-69	interleukin-8	Oreochromis niloticus	224-228
31838306-7	2020	Additionally, DLM toxicity downregulated the transcription of immune genes (IL-1beta and IL-8), while upregulated the stress related genes (HSP70 and CASP3).	decamethrin	14-17	interleukin-8	Oreochromis niloticus	89-93
31352117-8	2019	The mRNA expression profile of both interleukin 8 (IL-8), interleukin 1, beta (IL-1beta) encoding genes showed an up-regulation that was found in all Zn- supplemented groups, but more pronounced in nZnO60-supplemented group.	Zinc	150-152	interleukin-8	Oreochromis niloticus	36-49
31352117-8	2019	The mRNA expression profile of both interleukin 8 (IL-8), interleukin 1, beta (IL-1beta) encoding genes showed an up-regulation that was found in all Zn- supplemented groups, but more pronounced in nZnO60-supplemented group.	Zinc	150-152	interleukin-8	Oreochromis niloticus	51-55
31069608-4	2019	The group reared at 16-ppt salt showed better performance than that of 20 ppt, as they have lower morality % and higher expression of ion-regulated gene (Na+/K+-ATPase alpha1-b), stress-related genes (GST, HSP27, and HSP70) of the gills and also GST, inflammatory-related genes (IL-1beta and IL8), and TLR in the liver tissue.	16-ppt salt	20-31	interleukin-8	Oreochromis niloticus	292-295
28882806-7	2017	However, with the challenged group, 0.2% beta-Glucans showed better effect than 0.1% at day one post challenge through significant up-regulation of GST, HSP, IL8, TNF-alpha, CXC, and MHC-IIbeta, meanwhile, the effect of 0.1% was only on the expression of HSP70, MHC-IIbeta, and TLR7 at day 3 post challenge.	beta-Glucans	41-53	interleukin-8	Oreochromis niloticus	158-161