PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
33922251-3	2021	GENERAL CONTROL NON-REPRESSIBLE 5 (GCN5), a well-known enzymatic protein responsible for the lysine acetylation of histone H3 and H4, is a universal and crucial histone acetyltransferase involved in gene transcription and plant development.	Lysine	93-99	general control non-repressible 5	Arabidopsis thaliana	0-33
33922251-3	2021	GENERAL CONTROL NON-REPRESSIBLE 5 (GCN5), a well-known enzymatic protein responsible for the lysine acetylation of histone H3 and H4, is a universal and crucial histone acetyltransferase involved in gene transcription and plant development.	Lysine	93-99	general control non-repressible 5	Arabidopsis thaliana	35-39
33922251-5	2021	In terms of exogenous stress conditions, GCN5 is also involved in the responses to heat stress, cold stress, and nutrient element deficiency by regulating the related gene expression to maintain the homeostasis of some key metabolites (e.g., cellulose) or ions (e.g., phosphate, iron); in addition, GCN5 is involved in the phytohormone pathways such as ethylene, auxin, and salicylic acid to play various roles during the plant lifecycle.	Phosphates	268-277	general control non-repressible 5	Arabidopsis thaliana	41-45
33922251-5	2021	In terms of exogenous stress conditions, GCN5 is also involved in the responses to heat stress, cold stress, and nutrient element deficiency by regulating the related gene expression to maintain the homeostasis of some key metabolites (e.g., cellulose) or ions (e.g., phosphate, iron); in addition, GCN5 is involved in the phytohormone pathways such as ethylene, auxin, and salicylic acid to play various roles during the plant lifecycle.	Iron	279-283	general control non-repressible 5	Arabidopsis thaliana	41-45
33922251-5	2021	In terms of exogenous stress conditions, GCN5 is also involved in the responses to heat stress, cold stress, and nutrient element deficiency by regulating the related gene expression to maintain the homeostasis of some key metabolites (e.g., cellulose) or ions (e.g., phosphate, iron); in addition, GCN5 is involved in the phytohormone pathways such as ethylene, auxin, and salicylic acid to play various roles during the plant lifecycle.	ethylene	353-361	general control non-repressible 5	Arabidopsis thaliana	41-45
33922251-5	2021	In terms of exogenous stress conditions, GCN5 is also involved in the responses to heat stress, cold stress, and nutrient element deficiency by regulating the related gene expression to maintain the homeostasis of some key metabolites (e.g., cellulose) or ions (e.g., phosphate, iron); in addition, GCN5 is involved in the phytohormone pathways such as ethylene, auxin, and salicylic acid to play various roles during the plant lifecycle.	Indoleacetic Acids	363-368	general control non-repressible 5	Arabidopsis thaliana	41-45
33922251-5	2021	In terms of exogenous stress conditions, GCN5 is also involved in the responses to heat stress, cold stress, and nutrient element deficiency by regulating the related gene expression to maintain the homeostasis of some key metabolites (e.g., cellulose) or ions (e.g., phosphate, iron); in addition, GCN5 is involved in the phytohormone pathways such as ethylene, auxin, and salicylic acid to play various roles during the plant lifecycle.	Salicylic Acid	374-388	general control non-repressible 5	Arabidopsis thaliana	41-45
27500884-0	2016	Histone acetyltransferase general control non-repressed protein 5 (GCN5) affects the fatty acid composition of Arabidopsis thaliana seeds by acetylating fatty acid desaturase3 (FAD3).	Fatty Acids	85-95	general control non-repressible 5	Arabidopsis thaliana	67-71
30394596-4	2019	The levels of GCN5 mRNA are increased in response to salt stress.	Salts	53-57	general control non-repressible 5	Arabidopsis thaliana	14-18
30394596-9	2019	In addition, the expression of the wheat TaGCN5 gene in Arabidopsis gcn5 mutant plants complemented the salt tolerance and cell wall integrity phenotypes, suggesting that GCN5-mediated salt tolerance is conserved between Arabidopsis and wheat.	Salts	104-108	general control non-repressible 5	Arabidopsis thaliana	43-47
30394596-9	2019	In addition, the expression of the wheat TaGCN5 gene in Arabidopsis gcn5 mutant plants complemented the salt tolerance and cell wall integrity phenotypes, suggesting that GCN5-mediated salt tolerance is conserved between Arabidopsis and wheat.	Salts	185-189	general control non-repressible 5	Arabidopsis thaliana	43-47
30394596-10	2019	Taken together, our data indicate that GCN5 plays a key role in the preservation of salt tolerance via versatile regulation in plants.	Salts	84-88	general control non-repressible 5	Arabidopsis thaliana	39-43
29506042-0	2018	GCN5 contributes to stem cuticular wax biosynthesis by histone acetylation of CER3 in Arabidopsis.	Waxes	35-38	general control non-repressible 5	Arabidopsis thaliana	0-4
27500884-4	2016	Here, we demonstrate that a mutation of the histone acetyltransferase GCN5 can decrease the ratio of alpha-linolenic acid (ALA) to linoleic acid (LA) in seed oil.	alpha-Linolenic Acid	101-121	general control non-repressible 5	Arabidopsis thaliana	70-74
27500884-4	2016	Here, we demonstrate that a mutation of the histone acetyltransferase GCN5 can decrease the ratio of alpha-linolenic acid (ALA) to linoleic acid (LA) in seed oil.	alpha-Linolenic Acid	123-126	general control non-repressible 5	Arabidopsis thaliana	70-74
27500884-4	2016	Here, we demonstrate that a mutation of the histone acetyltransferase GCN5 can decrease the ratio of alpha-linolenic acid (ALA) to linoleic acid (LA) in seed oil.	Linoleic Acid	131-144	general control non-repressible 5	Arabidopsis thaliana	70-74
27500884-6	2016	Notably, the GCN5-dependent H3K9/14 acetylation of FAD3 determined the expression levels of FAD3 in Arabidopsis thaliana seeds, and the ratio of ALA/LA in the gcn5 mutant was rescued to the wild-type levels through the overexpression of FAD3.	alpha-Linolenic Acid	145-148	general control non-repressible 5	Arabidopsis thaliana	13-17
26596766-7	2016	Surprisingly, the clv1-1 gcn5-1 double mutant exhibited constitutive ethylene responses, suggesting that GCN5 and CLV signaling act synergistically to inhibit ethylene responses in Arabidopsis.	ethylene	69-77	general control non-repressible 5	Arabidopsis thaliana	25-29
26596766-0	2016	Synergistic action of histone acetyltransferase GCN5 and receptor CLAVATA1 negatively affects ethylene responses in Arabidopsis thaliana.	ethylene	94-102	general control non-repressible 5	Arabidopsis thaliana	48-52
26596766-7	2016	Surprisingly, the clv1-1 gcn5-1 double mutant exhibited constitutive ethylene responses, suggesting that GCN5 and CLV signaling act synergistically to inhibit ethylene responses in Arabidopsis.	ethylene	159-167	general control non-repressible 5	Arabidopsis thaliana	25-29
26596766-1	2016	GENERAL CONTROL NON-REPRESSIBLE 5 (GCN5) is a histone acetyltransferase (HAT) and the catalytic subunit of several multicomponent HAT complexes that acetylate lysine residues of histone H3.	Lysine	159-165	general control non-repressible 5	Arabidopsis thaliana	0-33
26596766-7	2016	Surprisingly, the clv1-1 gcn5-1 double mutant exhibited constitutive ethylene responses, suggesting that GCN5 and CLV signaling act synergistically to inhibit ethylene responses in Arabidopsis.	ethylene	159-167	general control non-repressible 5	Arabidopsis thaliana	105-109
26596766-1	2016	GENERAL CONTROL NON-REPRESSIBLE 5 (GCN5) is a histone acetyltransferase (HAT) and the catalytic subunit of several multicomponent HAT complexes that acetylate lysine residues of histone H3.	Lysine	159-165	general control non-repressible 5	Arabidopsis thaliana	35-39
26596766-9	2016	Our data suggest that signals from the CLV transduction pathway reach the GCN5-containing complexes in the nucleus and alter the histone acetylation status of ethylene-responsive genes, thus translating the CLV information to transcriptional activity and uncovering a link between histone acetylation and SAM maintenance in the complex mode of ethylene signaling.	ethylene	159-167	general control non-repressible 5	Arabidopsis thaliana	74-78
26596766-9	2016	Our data suggest that signals from the CLV transduction pathway reach the GCN5-containing complexes in the nucleus and alter the histone acetylation status of ethylene-responsive genes, thus translating the CLV information to transcriptional activity and uncovering a link between histone acetylation and SAM maintenance in the complex mode of ethylene signaling.	ethylene	344-352	general control non-repressible 5	Arabidopsis thaliana	74-78
26332346-7	2015	We find that TaGAMyb physically interacts with the wheat histone acetyltransferase TaGCN5 and also interacts with Arabidopsis thaliana AtGCN5.	tagamyb	13-20	general control non-repressible 5	Arabidopsis thaliana	135-141
26332346-10	2015	These results demonstrate that TaGAMyb plays a dual role in activating expression of glutenin gene by directly binding to the TaGLU promoter and by recruiting GCN5 to modulate histone acetylation during wheat endosperm development.	tagamyb	31-38	general control non-repressible 5	Arabidopsis thaliana	159-163
26002909-0	2015	GENERAL CONTROL NONREPRESSED PROTEIN5-Mediated Histone Acetylation of FERRIC REDUCTASE DEFECTIVE3 Contributes to Iron Homeostasis in Arabidopsis.	Iron	113-117	general control non-repressible 5	Arabidopsis thaliana	0-37
26002909-2	2015	Here, we report that a mutation in GENERAL CONTROL NONREPRESSED PROTEIN5 (GCN5) impaired iron translocation from the root to the shoot in Arabidopsis (Arabidopsis thaliana).	Iron	89-93	general control non-repressible 5	Arabidopsis thaliana	35-72
26002909-2	2015	Here, we report that a mutation in GENERAL CONTROL NONREPRESSED PROTEIN5 (GCN5) impaired iron translocation from the root to the shoot in Arabidopsis (Arabidopsis thaliana).	Iron	89-93	general control non-repressible 5	Arabidopsis thaliana	74-78
26002909-3	2015	Illumina high-throughput sequencing revealed 879 GCN5-regulated candidate genes potentially involved in iron homeostasis.	Iron	104-108	general control non-repressible 5	Arabidopsis thaliana	49-53
26002909-4	2015	Chromatin immunoprecipitation assays indicated that five genes (At3G08040, At2G01530, At2G39380, At2G47160, and At4G05200) are direct targets of GCN5 in iron homeostasis regulation.	Iron	153-157	general control non-repressible 5	Arabidopsis thaliana	145-149
26002909-5	2015	Notably, GCN5-mediated acetylation of histone 3 lysine 9 and histone 3 lysine 14 of FERRIC REDUCTASE DEFECTIVE3 (FRD3) determined the dynamic expression of FRD3.	Lysine	48-54	general control non-repressible 5	Arabidopsis thaliana	9-13
26002909-8	2015	Collectively, these data suggest that GCN5 plays a critical role in FRD3-mediated iron homeostasis.	Iron	82-86	general control non-repressible 5	Arabidopsis thaliana	38-42