PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
18497752-4	2008	Functional analysis showed that this mutation decreases MgATP hydrolysis by purified maltose-binding protein MBP-NBD1 fusion proteins.	Adenosine Triphosphate	56-61	myelin basic protein	Homo sapiens	109-117
18189317-3	2008	In the present study we show that inhibition of GSL synthesis with fumonisin B1 prevents clustering of MBP in GalC/Sulf-negative oligodendrocytes, suggesting that GSLs are required for the effect.	Glycosphingolipids	48-51	myelin basic protein	Homo sapiens	103-106
18189317-3	2008	In the present study we show that inhibition of GSL synthesis with fumonisin B1 prevents clustering of MBP in GalC/Sulf-negative oligodendrocytes, suggesting that GSLs are required for the effect.	Glycosphingolipids	163-167	myelin basic protein	Homo sapiens	103-106
18189317-1	2008	We showed previously that the addition to cultured oligodendrocytes (OLs) of multivalent carbohydrate in the form of liposomes containing the two major glycosphingolipids (GSLs) of myelin, galactosylceramide (GalC) and cerebroside sulfate (Sulf), or galactose conjugated to bovine serum albumin caused clustering of GalC on the extracellular surface and myelin basic protein (MBP) on the cytosolic surface.	Carbohydrates	89-101	myelin basic protein	Homo sapiens	354-374
18189317-1	2008	We showed previously that the addition to cultured oligodendrocytes (OLs) of multivalent carbohydrate in the form of liposomes containing the two major glycosphingolipids (GSLs) of myelin, galactosylceramide (GalC) and cerebroside sulfate (Sulf), or galactose conjugated to bovine serum albumin caused clustering of GalC on the extracellular surface and myelin basic protein (MBP) on the cytosolic surface.	Carbohydrates	89-101	myelin basic protein	Homo sapiens	376-379
18193902-5	2008	Changes in amino acid-assigned peaks before and after MBP-Ag4 bound maltose were used to assess protein orientation on the surface of silver nanoparticles.	CHEMBL1099124	58-61	myelin basic protein	Homo sapiens	54-57
18481290-2	2008	METHODS: BHT-3009 is a tolerizing DNA vaccine for MS, encoding full-length human myelin basic protein.	Butylated Hydroxytoluene	9-12	myelin basic protein	Homo sapiens	81-101
18227806-2	2008	The presence of citrulline in myelin proteins in particular myelin basic protein (MBP) causes an important change in myelin structure, which destabilizes myelin.	Citrulline	16-26	myelin basic protein	Homo sapiens	60-80
18227806-2	2008	The presence of citrulline in myelin proteins in particular myelin basic protein (MBP) causes an important change in myelin structure, which destabilizes myelin.	Citrulline	16-26	myelin basic protein	Homo sapiens	82-85
18260654-3	2008	Polyaniline was electrodeposited onto the sensors, and this modified surface then utilized to immobilize a biotinylated antibody for MBP using a classical avidin-biotin approach.	polyaniline	0-11	myelin basic protein	Homo sapiens	133-136
18322203-5	2008	The MS drug glatiramer acetate mimics the conformationally labile regions of MBP, interacts in the unfolded state strongly with alpha(M)beta(2), and inhibits the MBP binding to alpha(M)beta(2).	Glatiramer Acetate	12-30	myelin basic protein	Homo sapiens	77-80
18322203-5	2008	The MS drug glatiramer acetate mimics the conformationally labile regions of MBP, interacts in the unfolded state strongly with alpha(M)beta(2), and inhibits the MBP binding to alpha(M)beta(2).	Glatiramer Acetate	12-30	myelin basic protein	Homo sapiens	162-165
18322203-6	2008	Our study reveals a link between MBP, glatiramer acetate, and the alpha(M)beta(2) integrin, and suggests a new model for MS pathogenesis based on the recognition of unfolded MBP by the alpha(M)beta(2) integrin.	Glatiramer Acetate	38-56	myelin basic protein	Homo sapiens	174-177
18345967-9	2008	In a recent clinical trial, BHT-3009, a DNA vaccine encoding full-length human myelin basic protein, was tested in patient with MS. BHT-3009 was safe and well tolerated.	Butylated Hydroxytoluene	28-31	myelin basic protein	Homo sapiens	79-99
18345967-9	2008	In a recent clinical trial, BHT-3009, a DNA vaccine encoding full-length human myelin basic protein, was tested in patient with MS. BHT-3009 was safe and well tolerated.	Butylated Hydroxytoluene	132-135	myelin basic protein	Homo sapiens	79-99
18039685-0	2008	Biochemical characterization of phospholipids, sulfatide and heparin as potent stimulators for autophosphorylation of GSK-3beta and the GSK-3beta-mediated phosphorylation of myelin basic protein in vitro.	Phospholipids	32-45	myelin basic protein	Homo sapiens	174-194
18039685-0	2008	Biochemical characterization of phospholipids, sulfatide and heparin as potent stimulators for autophosphorylation of GSK-3beta and the GSK-3beta-mediated phosphorylation of myelin basic protein in vitro.	Heparin	61-68	myelin basic protein	Homo sapiens	174-194
18039685-2	2008	It was found that (i) both PI and SH highly stimulated the GSK-3beta-mediated phosphorylation of MBP, but not glycogen synthase, and two MBP peptides through their direct binding to these substrates and (ii) both PI and heparin, as compared with sulfatide, highly stimulated autophosphorylation of GSK-3beta.	Heparin	220-227	myelin basic protein	Homo sapiens	97-100
18039685-2	2008	It was found that (i) both PI and SH highly stimulated the GSK-3beta-mediated phosphorylation of MBP, but not glycogen synthase, and two MBP peptides through their direct binding to these substrates and (ii) both PI and heparin, as compared with sulfatide, highly stimulated autophosphorylation of GSK-3beta.	Sulfoglycosphingolipids	246-255	myelin basic protein	Homo sapiens	97-100
18039685-5	2008	These results presented here suggest that these two phospholipids and SH may function as effective stimulators for autophosphorylation of GSK-3beta and for the GSK-3beta-mediated high phosphorylation of SH-binding proteins, including MBP and TP, in the highly accumulated levels of these acidic and sulfated modulators in the brain.	Phospholipids	52-65	myelin basic protein	Homo sapiens	234-237
18053806-6	2008	MEK kinase assay using myelin basic protein (MBP) revealed that TPA-augmented MEK activity in HT-1080 cells and that the augmented MEK activity was diminished by nobiletin treatment.	Tetradecanoylphorbol Acetate	64-67	myelin basic protein	Homo sapiens	23-43
18053806-6	2008	MEK kinase assay using myelin basic protein (MBP) revealed that TPA-augmented MEK activity in HT-1080 cells and that the augmented MEK activity was diminished by nobiletin treatment.	Tetradecanoylphorbol Acetate	64-67	myelin basic protein	Homo sapiens	45-48
18053806-6	2008	MEK kinase assay using myelin basic protein (MBP) revealed that TPA-augmented MEK activity in HT-1080 cells and that the augmented MEK activity was diminished by nobiletin treatment.	nobiletin	162-171	myelin basic protein	Homo sapiens	23-43
18053806-6	2008	MEK kinase assay using myelin basic protein (MBP) revealed that TPA-augmented MEK activity in HT-1080 cells and that the augmented MEK activity was diminished by nobiletin treatment.	nobiletin	162-171	myelin basic protein	Homo sapiens	45-48
18053806-8	2008	Furthermore, when an immunoprecipitated active MEK was incubated with nobiletin under cell-free conditions, nobiletin was found to inhibit the MEK-mediated MBP phosphorylation.	nobiletin	70-79	myelin basic protein	Homo sapiens	156-159
18053806-8	2008	Furthermore, when an immunoprecipitated active MEK was incubated with nobiletin under cell-free conditions, nobiletin was found to inhibit the MEK-mediated MBP phosphorylation.	nobiletin	108-117	myelin basic protein	Homo sapiens	156-159
18193902-5	2008	Changes in amino acid-assigned peaks before and after MBP-Ag4 bound maltose were used to assess protein orientation on the surface of silver nanoparticles.	Maltose	68-75	myelin basic protein	Homo sapiens	54-57
18081283-1	2008	We demonstrate that the Atomic Force Microscope (AFM) can be used to immobilize a dicysteine-terminated protein (Maltose Binding Protein, MBP-cys-cys for short) at well-defined locations directly on gold substrates via nanografting and characterize the in situ bioactivity of these proteins within the fabricated nanopatterns.	Cystine	82-92	myelin basic protein	Homo sapiens	138-141
18067320-0	2008	Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.	Proline	15-22	myelin basic protein	Homo sapiens	39-59
18067320-2	2008	A central segment of MBP is highly conserved in mammals and consists of a membrane surface-associated amphipathic alpha-helix, immediately followed by a proline-rich segment that we hypothesize is an SH3 ligand.	Proline	153-160	myelin basic protein	Homo sapiens	21-24
18067320-8	2008	Molecular docking simulations of the interaction of the putative SH3 ligand of classic MBP with the human Fyn SH3 domain indicate that the strength of the interaction is of the same order of magnitude as with calmodulin and that the molecular recognition and association is mediated by some weak CH...pi interactions between the ligand prolyl residues and the aromatic ones of the SH3 binding site.	Peptide oostatic hormone	336-342	myelin basic protein	Homo sapiens	87-90
18067320-9	2008	One such interaction is well-conserved and involves the stacking of an MBP-peptide prolyl and an SH3 domain tryptophanyl residue, as in most other SH3-ligand complexes.	tryptophanyl	108-120	myelin basic protein	Homo sapiens	71-74
18081283-1	2008	We demonstrate that the Atomic Force Microscope (AFM) can be used to immobilize a dicysteine-terminated protein (Maltose Binding Protein, MBP-cys-cys for short) at well-defined locations directly on gold substrates via nanografting and characterize the in situ bioactivity of these proteins within the fabricated nanopatterns.	Cysteine	84-87	myelin basic protein	Homo sapiens	138-141
18081283-1	2008	We demonstrate that the Atomic Force Microscope (AFM) can be used to immobilize a dicysteine-terminated protein (Maltose Binding Protein, MBP-cys-cys for short) at well-defined locations directly on gold substrates via nanografting and characterize the in situ bioactivity of these proteins within the fabricated nanopatterns.	Cysteine	142-145	myelin basic protein	Homo sapiens	138-141
18081283-3	2008	The maltose-mediated conformational changes within the MBP have been found to change the AFM-tip-protein interaction, therefore causing the frictional signal to change.	Maltose	4-11	myelin basic protein	Homo sapiens	55-58
18081283-6	2008	By measuring the change in the frictional force above the protein nanopatterns as a function of maltose concentration, we determined the dissociation constant for the MBP-cys-cys/maltose system to be kd = (1 +/- 0.04) microM.	Maltose	96-103	myelin basic protein	Homo sapiens	167-170
18081283-6	2008	By measuring the change in the frictional force above the protein nanopatterns as a function of maltose concentration, we determined the dissociation constant for the MBP-cys-cys/maltose system to be kd = (1 +/- 0.04) microM.	Cysteine	171-174	myelin basic protein	Homo sapiens	167-170
18081283-6	2008	By measuring the change in the frictional force above the protein nanopatterns as a function of maltose concentration, we determined the dissociation constant for the MBP-cys-cys/maltose system to be kd = (1 +/- 0.04) microM.	Cysteine	175-178	myelin basic protein	Homo sapiens	167-170
18081283-6	2008	By measuring the change in the frictional force above the protein nanopatterns as a function of maltose concentration, we determined the dissociation constant for the MBP-cys-cys/maltose system to be kd = (1 +/- 0.04) microM.	Maltose	179-186	myelin basic protein	Homo sapiens	167-170
18081283-7	2008	Our results show that the MBP-cys-cys system provides a very sensitive surface-based, protein nanobiosensor for maltose detection at the attogram level (approximately 100 nM concentration).	Cysteine	30-33	myelin basic protein	Homo sapiens	26-29
18081283-7	2008	Our results show that the MBP-cys-cys system provides a very sensitive surface-based, protein nanobiosensor for maltose detection at the attogram level (approximately 100 nM concentration).	Cysteine	34-37	myelin basic protein	Homo sapiens	26-29
18081283-7	2008	Our results show that the MBP-cys-cys system provides a very sensitive surface-based, protein nanobiosensor for maltose detection at the attogram level (approximately 100 nM concentration).	Maltose	112-119	myelin basic protein	Homo sapiens	26-29
18607107-1	2008	BACKGROUND: Copaxone (glatiramer acetate) is a synthetic copolymer mimicking a portion of myelin basic protein, one of several putative autoantigens in multiple sclerosis (MS).	Glatiramer Acetate	12-20	myelin basic protein	Homo sapiens	90-110
18189256-3	2008	With the mono-His6-tagged maltose binding protein (His6-MBP), thermodynamic modeling based on surface plasmon resonance (SPR) titration data showed that the MBP molecules in solution were linked, on average, to Ni.4 in 1:1 stoichiometry.	Maltose	26-33	myelin basic protein	Homo sapiens	56-59
18189256-3	2008	With the mono-His6-tagged maltose binding protein (His6-MBP), thermodynamic modeling based on surface plasmon resonance (SPR) titration data showed that the MBP molecules in solution were linked, on average, to Ni.4 in 1:1 stoichiometry.	Maltose	26-33	myelin basic protein	Homo sapiens	157-160
18189256-4	2008	On the surface, however, the majority of His(6)-MBP was complexed to surface-immobilized beta-CDs through three Ni.4 complexes.	betadex	89-97	myelin basic protein	Homo sapiens	48-51
18607107-1	2008	BACKGROUND: Copaxone (glatiramer acetate) is a synthetic copolymer mimicking a portion of myelin basic protein, one of several putative autoantigens in multiple sclerosis (MS).	Glatiramer Acetate	22-40	myelin basic protein	Homo sapiens	90-110
18607107-1	2008	BACKGROUND: Copaxone (glatiramer acetate) is a synthetic copolymer mimicking a portion of myelin basic protein, one of several putative autoantigens in multiple sclerosis (MS).	copolymer	57-66	myelin basic protein	Homo sapiens	90-110
18173745-7	2008	Treatment of cells with actinomycin D (ActD), cisplatin or UV, all of which inhibit ribosome biogenesis, induced processing of p160(MBP) into p140(MBP) and p67(MBP).	Dactinomycin	24-37	myelin basic protein	Homo sapiens	132-135
18173745-7	2008	Treatment of cells with actinomycin D (ActD), cisplatin or UV, all of which inhibit ribosome biogenesis, induced processing of p160(MBP) into p140(MBP) and p67(MBP).	Dactinomycin	24-37	myelin basic protein	Homo sapiens	147-150
18173745-7	2008	Treatment of cells with actinomycin D (ActD), cisplatin or UV, all of which inhibit ribosome biogenesis, induced processing of p160(MBP) into p140(MBP) and p67(MBP).	Dactinomycin	24-37	myelin basic protein	Homo sapiens	147-150
18173745-7	2008	Treatment of cells with actinomycin D (ActD), cisplatin or UV, all of which inhibit ribosome biogenesis, induced processing of p160(MBP) into p140(MBP) and p67(MBP).	Cisplatin	46-55	myelin basic protein	Homo sapiens	132-135
18173745-7	2008	Treatment of cells with actinomycin D (ActD), cisplatin or UV, all of which inhibit ribosome biogenesis, induced processing of p160(MBP) into p140(MBP) and p67(MBP).	Cisplatin	46-55	myelin basic protein	Homo sapiens	147-150
18173745-7	2008	Treatment of cells with actinomycin D (ActD), cisplatin or UV, all of which inhibit ribosome biogenesis, induced processing of p160(MBP) into p140(MBP) and p67(MBP).	Cisplatin	46-55	myelin basic protein	Homo sapiens	147-150
17823123-3	2007	Here we describe that after Th2 polarization by gemfibrozil or other drugs, MBP-primed T cells induced the expression of neurotrophic molecules such as brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3), but not proinflammatory molecules in microglia and astroglia via cell-to-cell contact.	Gemfibrozil	48-59	myelin basic protein	Homo sapiens	76-79
17979262-0	2007	Putative bioactive conformations of amide linked cyclic myelin basic protein peptide analogues associated with experimental autoimmune encephalomyelitis.	Amides	36-41	myelin basic protein	Homo sapiens	56-76
18855760-2	2008	The soluble fusion protein MBP-Gly1-Gln26-rhPTH(1-34) was harvested after purification by Phenyl-Sepharose F.F and Q-Sepharose F.F chromatographies.	phenyl-sepharose	90-106	myelin basic protein	Homo sapiens	27-30
18855760-2	2008	The soluble fusion protein MBP-Gly1-Gln26-rhPTH(1-34) was harvested after purification by Phenyl-Sepharose F.F and Q-Sepharose F.F chromatographies.	Sepharose	97-106	myelin basic protein	Homo sapiens	27-30
17729284-3	2007	Inhibition of p38 with PD169316 and SB203580 prevented accumulation of protein and mRNA of cell-stage specific markers characteristic of differentiated oligodendrocytes, including myelin basic protein, myelin-associated glycoprotein, and the glycosphingolipids, galactosylceramide and sulfatide.	2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole	23-31	myelin basic protein	Homo sapiens	180-200
17729284-3	2007	Inhibition of p38 with PD169316 and SB203580 prevented accumulation of protein and mRNA of cell-stage specific markers characteristic of differentiated oligodendrocytes, including myelin basic protein, myelin-associated glycoprotein, and the glycosphingolipids, galactosylceramide and sulfatide.	SB 203580	36-44	myelin basic protein	Homo sapiens	180-200
17960247-5	2007	Here we show that although paramagnetic relaxation enhancement (PRE) data for the sugar-bound form are consistent with the crystal structure of holo MBP, the PRE data for the apo state are indicative of a rapidly exchanging mixture (ns to mus regime) of a predominantly ( approximately 95%) open form (represented by the apo crystal structure) and a minor (approximately 5%) partially closed species.	Sugars	82-87	myelin basic protein	Homo sapiens	149-152
17902702-3	2007	In contrast to the single Cys to Ser mutations of the CCS-MBP protein (Stasser, J. P., Eisses, J. F., Barry, A. N., Kaplan, J. H., and Blackburn, N. J.	Serine	33-36	myelin basic protein	Homo sapiens	58-61
17939756-4	2007	We determined that MBP is phosphorylated by PKD on Ser-160 and that this phosphorylation can be quantified in ELISAs, by the use of phosphorylation site-specific antibodies.	Serine	51-54	myelin basic protein	Homo sapiens	19-22
17939756-5	2007	Antibodies were developed that are highly specific for the MBP peptide sequence surrounding the phosphorylated Ser-160.	Serine	111-114	myelin basic protein	Homo sapiens	59-62
17513373-5	2007	In this article we study the interaction of MBP with Langmuir films of anionic and neutral phospholipids, used as experimental models of the lipid membrane.	Phospholipids	91-104	myelin basic protein	Homo sapiens	44-47
17698695-1	2007	OBJECTIVE: To assess safety and immune modulation by BHT-3009, a tolerizing DNA vaccine encoding full-length human myelin basic protein, in patients with multiple sclerosis (MS).	Butylated Hydroxytoluene	53-56	myelin basic protein	Homo sapiens	115-135
17628700-6	2007	Glutamate concentrations above 10 muM appeared to be inhibitory on MBP and MOG-specific T-lymphocyte proliferation as well as chemotactic response in both patients and controls.	Glutamic Acid	0-9	myelin basic protein	Homo sapiens	67-70
17985666-7	2007	Although a MBP layer in conjunction with water-consumptive trees can reduce vertical water losses as compared to mineral substrates, the effect is not sufficient to meet legal regulations.	Water	85-90	myelin basic protein	Homo sapiens	11-14
17643935-1	2007	Glatiramer acetate (GA) is a mixture of synthetic polypeptides composed of four amino acids resembling myelin basic protein (MBP).	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	103-123
17643935-1	2007	Glatiramer acetate (GA) is a mixture of synthetic polypeptides composed of four amino acids resembling myelin basic protein (MBP).	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	125-128
17643935-1	2007	Glatiramer acetate (GA) is a mixture of synthetic polypeptides composed of four amino acids resembling myelin basic protein (MBP).	Glatiramer Acetate	20-22	myelin basic protein	Homo sapiens	103-123
17643935-1	2007	Glatiramer acetate (GA) is a mixture of synthetic polypeptides composed of four amino acids resembling myelin basic protein (MBP).	Glatiramer Acetate	20-22	myelin basic protein	Homo sapiens	125-128
17881403-1	2007	Glatiramer acetate (GA), a well tolerated immunomodulatory treatment for relapsing-remitting multiple sclerosis (RR-MS), consists of a 4-amino acid polymer that mimics the myelin basic protein (MBP).	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	172-192
17616158-1	2007	Multilayers consisting of negatively charged phospholipid DMPA and myelin basic protein (MBP) were assembled by Langmuir-Blodgett deposition of floating Langmuir monolayers from the air/water interface to solid substrates.	Water	186-191	myelin basic protein	Homo sapiens	89-92
17881403-1	2007	Glatiramer acetate (GA), a well tolerated immunomodulatory treatment for relapsing-remitting multiple sclerosis (RR-MS), consists of a 4-amino acid polymer that mimics the myelin basic protein (MBP).	Glatiramer Acetate	20-22	myelin basic protein	Homo sapiens	172-192
17881403-1	2007	Glatiramer acetate (GA), a well tolerated immunomodulatory treatment for relapsing-remitting multiple sclerosis (RR-MS), consists of a 4-amino acid polymer that mimics the myelin basic protein (MBP).	4-amino acid	135-147	myelin basic protein	Homo sapiens	172-192
17616158-10	2007	Here, the water molecules were found to be a necessary mediator to maintain the laminar order in a multilayer from DMPA and myelin basic protein.	Water	10-15	myelin basic protein	Homo sapiens	124-144
17442667-1	2007	Mannan-binding protein (MBP) is a C-type mammalian lectin specific for mannose and N-acetylglucosamine.	Mannose	71-78	myelin basic protein	Homo sapiens	0-22
17442667-1	2007	Mannan-binding protein (MBP) is a C-type mammalian lectin specific for mannose and N-acetylglucosamine.	Mannose	71-78	myelin basic protein	Homo sapiens	24-27
17442667-1	2007	Mannan-binding protein (MBP) is a C-type mammalian lectin specific for mannose and N-acetylglucosamine.	Acetylglucosamine	83-102	myelin basic protein	Homo sapiens	0-22
17442667-1	2007	Mannan-binding protein (MBP) is a C-type mammalian lectin specific for mannose and N-acetylglucosamine.	Acetylglucosamine	83-102	myelin basic protein	Homo sapiens	24-27
17442667-11	2007	However, the subcellular localization of either a mutant (C236S/C244S) I-MBP, which lacks carbohydrate-binding activity, or the wild-type I-MBP in tunicamycin-treated cells shows an equally diffuse cytoplasmic distribution, suggesting that the unique accumulation of I-MBP in the ER and COPII vesicles is mediated by an N-glycan-lectin interaction.	Tunicamycin	147-158	myelin basic protein	Homo sapiens	140-143
17442667-11	2007	However, the subcellular localization of either a mutant (C236S/C244S) I-MBP, which lacks carbohydrate-binding activity, or the wild-type I-MBP in tunicamycin-treated cells shows an equally diffuse cytoplasmic distribution, suggesting that the unique accumulation of I-MBP in the ER and COPII vesicles is mediated by an N-glycan-lectin interaction.	Tunicamycin	147-158	myelin basic protein	Homo sapiens	140-143
17442667-12	2007	Furthermore, the binding of I-MBP with glycoprotein intermediates occurs in the ER, which is carbohydrate- and pH-dependent, and is affected by glucose-trimmed high-mannose-type oligosaccharides.	Carbohydrates	93-105	myelin basic protein	Homo sapiens	30-33
17442667-12	2007	Furthermore, the binding of I-MBP with glycoprotein intermediates occurs in the ER, which is carbohydrate- and pH-dependent, and is affected by glucose-trimmed high-mannose-type oligosaccharides.	Glucose	144-151	myelin basic protein	Homo sapiens	30-33
17442667-12	2007	Furthermore, the binding of I-MBP with glycoprotein intermediates occurs in the ER, which is carbohydrate- and pH-dependent, and is affected by glucose-trimmed high-mannose-type oligosaccharides.	mannose-type oligosaccharides	165-194	myelin basic protein	Homo sapiens	30-33
17499675-0	2007	Recurrent myelin basic protein elevation in cerebrospinal fluid as a predictive marker of delayed encephalopathy after carbon monoxide poisoning.	Carbon Monoxide	119-134	myelin basic protein	Homo sapiens	10-30
17638403-4	2007	The results show that in intact cells, after accumulation of decays at -70 degrees C in the presence of 10% DMSO, almost four times more DSBs were induced in late S phase compared with early S phase and the fragment distribution was clearly non-random with an excess of fragments <0.2 Mbp.	Dimethyl Sulfoxide	108-112	myelin basic protein	Homo sapiens	288-291
17400921-3	2007	We have previously created several heterotropic allosteric enzymes by recombining the genes for TEM1 beta-lactamase (BLA) and maltose binding protein (MBP) to create BLAs that are positively or negatively regulated by maltose.	Maltose	126-133	myelin basic protein	Homo sapiens	151-154
17451814-3	2007	Two of the nine MBP reactive Fabs were also reactive to GFAP and CNPase, indicating that these clones were polyreactive.	FAB protocol	29-33	myelin basic protein	Homo sapiens	16-19
17235686-5	2007	Pharmacological inhibition of p38 interfered with the morphological and antigenic changes associated with differentiating oligodendrocytes as well as with the developmental and forskolin-induced expression of myelin basic protein, thereby supporting an essential role for p38 MAPK pathway in oligodendrocyte differentiation.	Colforsin	177-186	myelin basic protein	Homo sapiens	209-229
17348702-8	2007	We have demonstrated the applicability of C18-functionalized Fe3O4 nanoparticles in the detection of in vitro phosphorylation sites on the myelin basic protein, and at least 17 phosphopeptides were identified, including one previously uncharacterized site.	1-octadecene	42-45	myelin basic protein	Homo sapiens	139-159
17348702-8	2007	We have demonstrated the applicability of C18-functionalized Fe3O4 nanoparticles in the detection of in vitro phosphorylation sites on the myelin basic protein, and at least 17 phosphopeptides were identified, including one previously uncharacterized site.	ferryl iron	61-66	myelin basic protein	Homo sapiens	139-159
19300558-2	2007	It consists of a copolymer of amino acid residues in the same stoichiometric proportions as in myelin basic protein.	copolymer	17-26	myelin basic protein	Homo sapiens	95-115
17488478-4	2007	When GOTO cells were grown in the presence of 5-bromo-2"-deoxyuridine (BrdU), they increased the expressions of two HOX genes (HOXC6 and HOXC11) and marker genes for Schwannian cells (S100beta and myelin basic protein).	Bromodeoxyuridine	46-69	myelin basic protein	Homo sapiens	197-217
17488478-4	2007	When GOTO cells were grown in the presence of 5-bromo-2"-deoxyuridine (BrdU), they increased the expressions of two HOX genes (HOXC6 and HOXC11) and marker genes for Schwannian cells (S100beta and myelin basic protein).	Bromodeoxyuridine	71-75	myelin basic protein	Homo sapiens	197-217
16900293-0	2007	A tale of two citrullines--structural and functional aspects of myelin basic protein deimination in health and disease.	Citrulline	14-25	myelin basic protein	Homo sapiens	64-84
17263673-8	2007	Significant between-group differences (iTBI vs. nTBI) were found for time to peak NSE (66.48 +/- 53.56 vs.8.11 +/- 11.58), S100B (43.30 +/- 51.41 vs. 8.21 +/- 8.29), and MBP (77.66 +/- 56.77 vs. 21.63 +/- 28.39).	itbi	39-43	myelin basic protein	Homo sapiens	170-173
17713031-4	2007	Moreover, mast cells are often found close to MS plaques, and the main MS antigen, myelin basic protein (MBP), can activate human cultured mast cells to release IL-8, TNF-alpha, tryptase, and histamine.	Histamine	192-201	myelin basic protein	Homo sapiens	83-103
17713031-4	2007	Moreover, mast cells are often found close to MS plaques, and the main MS antigen, myelin basic protein (MBP), can activate human cultured mast cells to release IL-8, TNF-alpha, tryptase, and histamine.	Histamine	192-201	myelin basic protein	Homo sapiens	105-108
17762198-3	2007	Moreover, late addition of IGF-1 to OPs previously exposed to toxic levels of glutamate promotes oligodendrocyte maturation as measured by myelin basic protein expression.	Glutamic Acid	78-87	myelin basic protein	Homo sapiens	139-159
17531858-1	2007	Glatiramer acetate (GA), formerly known as copolymer 1, is a mixture of synthetic polypeptides composed of four amino acids resembling the myelin basic protein (MSP).	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	139-159
17531858-1	2007	Glatiramer acetate (GA), formerly known as copolymer 1, is a mixture of synthetic polypeptides composed of four amino acids resembling the myelin basic protein (MSP).	Glatiramer Acetate	20-22	myelin basic protein	Homo sapiens	139-159
17531858-1	2007	Glatiramer acetate (GA), formerly known as copolymer 1, is a mixture of synthetic polypeptides composed of four amino acids resembling the myelin basic protein (MSP).	copolymer	43-52	myelin basic protein	Homo sapiens	139-159
17263673-8	2007	Significant between-group differences (iTBI vs. nTBI) were found for time to peak NSE (66.48 +/- 53.56 vs.8.11 +/- 11.58), S100B (43.30 +/- 51.41 vs. 8.21 +/- 8.29), and MBP (77.66 +/- 56.77 vs. 21.63 +/- 28.39).	ntbi	48-52	myelin basic protein	Homo sapiens	170-173
17056157-6	2007	LPA also caused a down-regulation of myelin proteins, such as myelin basic protein (MBP) and myelin protein zero (MPZ) to approximately 70% of control.	lysophosphatidic acid	0-3	myelin basic protein	Homo sapiens	62-82
17056157-6	2007	LPA also caused a down-regulation of myelin proteins, such as myelin basic protein (MBP) and myelin protein zero (MPZ) to approximately 70% of control.	lysophosphatidic acid	0-3	myelin basic protein	Homo sapiens	84-87
17125414-4	2006	The drug is a synthetic copolymer of four amino acids based on the composition of myelin basic protein, one of several putative autoantigens implicated in the pathogenesis of MS. Three separate double-blind, placebo-controlled trials have established its efficacy in relapsing-remitting MS. Observations from an ongoing study, the longest prospective study in MS therapeutics so far, suggest that the effect of GA in reducing the relapse rate and neurological disability is maintained over a 10-year period.	Glatiramer Acetate	411-413	myelin basic protein	Homo sapiens	82-102
17154537-3	2006	We have attempted to determine the magnitude of cation-pi interactions of Lys with aromatic amino acids in four different proteins (LIVBP, MBP, RBP, and Trx).	Lysine	74-77	myelin basic protein	Homo sapiens	139-142
16940047-2	2006	The crystal structure of MBP resembles that of the C-type lectin (CTL) superfamily, and recent data showed that MBP binds heparan sulfate glycosaminoglycan (GAG), with the CTL ligand-binding region as the binding site.	heparan sulfate glycosaminoglycan	122-155	myelin basic protein	Homo sapiens	25-28
16556666-5	2006	RESULTS: Numbers of intraepithelial eosinophils were significantly higher with MBP immunostaining than with haematoxylin and eosin staining (mean 109.6 v 80.6; p<0.001), whereas numbers of eosinophils were considerably correlated (r = 0.794).	Eosine Yellowish-(YS)	36-41	myelin basic protein	Homo sapiens	79-82
17080338-5	2006	There is convincing evidence that AMP is caused by spinal cord toxicity of intrathecally applied toxic agents such as cytarabin and/or methotrexate leading to spinal demyelinisation as demonstrated by elevated myelin basic protein in cerebrospinal fluid.	Adenosine Monophosphate	34-37	myelin basic protein	Homo sapiens	210-230
17080338-5	2006	There is convincing evidence that AMP is caused by spinal cord toxicity of intrathecally applied toxic agents such as cytarabin and/or methotrexate leading to spinal demyelinisation as demonstrated by elevated myelin basic protein in cerebrospinal fluid.	Cytarabine	118-127	myelin basic protein	Homo sapiens	210-230
17080338-5	2006	There is convincing evidence that AMP is caused by spinal cord toxicity of intrathecally applied toxic agents such as cytarabin and/or methotrexate leading to spinal demyelinisation as demonstrated by elevated myelin basic protein in cerebrospinal fluid.	Methotrexate	135-147	myelin basic protein	Homo sapiens	210-230
16940047-2	2006	The crystal structure of MBP resembles that of the C-type lectin (CTL) superfamily, and recent data showed that MBP binds heparan sulfate glycosaminoglycan (GAG), with the CTL ligand-binding region as the binding site.	heparan sulfate glycosaminoglycan	122-155	myelin basic protein	Homo sapiens	112-115
16940047-2	2006	The crystal structure of MBP resembles that of the C-type lectin (CTL) superfamily, and recent data showed that MBP binds heparan sulfate glycosaminoglycan (GAG), with the CTL ligand-binding region as the binding site.	Glycosaminoglycans	157-160	myelin basic protein	Homo sapiens	25-28
16940047-2	2006	The crystal structure of MBP resembles that of the C-type lectin (CTL) superfamily, and recent data showed that MBP binds heparan sulfate glycosaminoglycan (GAG), with the CTL ligand-binding region as the binding site.	Glycosaminoglycans	157-160	myelin basic protein	Homo sapiens	112-115
16940047-4	2006	Using flow cytometry and site-directed mutagenesis, we demonstrate here that the MBP domain of pro-MBP binds to heparan sulfate GAG on the cell surface and that this is independent of GAG covalently bound to pro-MBP.	Heparitin Sulfate	112-127	myelin basic protein	Homo sapiens	81-84
16940047-4	2006	Using flow cytometry and site-directed mutagenesis, we demonstrate here that the MBP domain of pro-MBP binds to heparan sulfate GAG on the cell surface and that this is independent of GAG covalently bound to pro-MBP.	Glycosaminoglycans	128-131	myelin basic protein	Homo sapiens	81-84
16940047-5	2006	Eight basic residues located in the CTL ligand-binding region of MBP were hypothesized previously to mediate GAG binding, but we found that surface binding was not compromised by the substitution of these residues with alanine.	Glycosaminoglycans	109-112	myelin basic protein	Homo sapiens	65-68
16940047-5	2006	Eight basic residues located in the CTL ligand-binding region of MBP were hypothesized previously to mediate GAG binding, but we found that surface binding was not compromised by the substitution of these residues with alanine.	Alanine	219-226	myelin basic protein	Homo sapiens	65-68
16794783-5	2006	Some size isoforms of MBP are transported into the nucleus and thus they may also bind polynucleotides.	Polynucleotides	87-102	myelin basic protein	Homo sapiens	22-25
16982928-5	2006	Cell stimulation with the synthetic polycation, poly-L-arginine, reproduced some but not all effects of MBP and EPO.	polyarginine	48-63	myelin basic protein	Homo sapiens	104-107
16982928-6	2006	Finally, simultaneous cell incubation with the polyanion molecules, poly-L-glutamic acid or heparin, restored MMP-1 gene expression but incompletely inhibited MBP- and EPO-induced transcriptional effects as well as endothelin-1 and PDGF-AB release, suggesting that cationic proteins act partially through their cationic charge.	polyanions	47-56	myelin basic protein	Homo sapiens	159-162
16982928-6	2006	Finally, simultaneous cell incubation with the polyanion molecules, poly-L-glutamic acid or heparin, restored MMP-1 gene expression but incompletely inhibited MBP- and EPO-induced transcriptional effects as well as endothelin-1 and PDGF-AB release, suggesting that cationic proteins act partially through their cationic charge.	Polyglutamic Acid	68-88	myelin basic protein	Homo sapiens	159-162
16982928-6	2006	Finally, simultaneous cell incubation with the polyanion molecules, poly-L-glutamic acid or heparin, restored MMP-1 gene expression but incompletely inhibited MBP- and EPO-induced transcriptional effects as well as endothelin-1 and PDGF-AB release, suggesting that cationic proteins act partially through their cationic charge.	Heparin	92-99	myelin basic protein	Homo sapiens	159-162
16310386-1	2006	[Arg(91), Ala(96)] MBP(87-99) is an altered peptide ligand (APL) of myelin basic protein (MBP), shown to actively inhibit experimental autoimmune encephalomyelitis (EAE), which is studied as a model of multiple sclerosis (MS).	Arginine	1-4	myelin basic protein	Homo sapiens	19-22
16782028-3	2006	We report here that golli protein, an alternatively spliced product of the myelin basic protein gene, plays a critical role in regulating calcium influx in T cells.	Calcium	138-145	myelin basic protein	Homo sapiens	75-95
16310386-1	2006	[Arg(91), Ala(96)] MBP(87-99) is an altered peptide ligand (APL) of myelin basic protein (MBP), shown to actively inhibit experimental autoimmune encephalomyelitis (EAE), which is studied as a model of multiple sclerosis (MS).	Arginine	1-4	myelin basic protein	Homo sapiens	68-88
16310386-1	2006	[Arg(91), Ala(96)] MBP(87-99) is an altered peptide ligand (APL) of myelin basic protein (MBP), shown to actively inhibit experimental autoimmune encephalomyelitis (EAE), which is studied as a model of multiple sclerosis (MS).	Arginine	1-4	myelin basic protein	Homo sapiens	90-93
16310386-1	2006	[Arg(91), Ala(96)] MBP(87-99) is an altered peptide ligand (APL) of myelin basic protein (MBP), shown to actively inhibit experimental autoimmune encephalomyelitis (EAE), which is studied as a model of multiple sclerosis (MS).	Alanine	10-13	myelin basic protein	Homo sapiens	19-22
16310386-1	2006	[Arg(91), Ala(96)] MBP(87-99) is an altered peptide ligand (APL) of myelin basic protein (MBP), shown to actively inhibit experimental autoimmune encephalomyelitis (EAE), which is studied as a model of multiple sclerosis (MS).	Alanine	10-13	myelin basic protein	Homo sapiens	68-88
16310386-1	2006	[Arg(91), Ala(96)] MBP(87-99) is an altered peptide ligand (APL) of myelin basic protein (MBP), shown to actively inhibit experimental autoimmune encephalomyelitis (EAE), which is studied as a model of multiple sclerosis (MS).	Alanine	10-13	myelin basic protein	Homo sapiens	90-93
16879301-1	2006	MBP8298 is a synthetic peptide with a sequence corresponding to amino acid residues 82-98 of human myelin basic protein (DENPVVHFFKNIVTPRT).	Peptides	23-30	myelin basic protein	Homo sapiens	99-119
16705196-1	2006	AIM: To investigate whether the presence of serum antibodies against myelin oligodendrocyte glycoprotein (MOG) and myelin basic protein (MBP) in patients with a clinically isolated syndrome (CIS) predicts the interval to develop more frequently and earlier a first relapse (clinically definite multiple sclerosis: CDMS) than seronegative patients.	cdms	314-318	myelin basic protein	Homo sapiens	137-140
16536470-3	2006	Conjugation of the dyes to the S337C maltose binding protein (MBP) mutant provided conjugates of these dyes that are capable of detecting maltose with different sensitivities.	Maltose	37-44	myelin basic protein	Homo sapiens	62-65
16802872-5	2006	This occurred because iron ions produce DNA fragments smaller than 0.75 Mbp with a higher probability than gamma rays (a probability that increases with LET).	Iron	22-26	myelin basic protein	Homo sapiens	72-75
16595889-8	2006	Clustering of mannose residues on liposomal surfaces might be important in determining the binding affinity of mannosylated liposomes with MBP.	Mannose	14-21	myelin basic protein	Homo sapiens	139-142
16608409-6	2006	The drug or therapeutic vaccine against the exacerbating-remitting type of multiple sclerosis is a copolymer of four amino acid residues, denoted Copaxone, which are related to myelin basic protein.	Glatiramer Acetate	146-154	myelin basic protein	Homo sapiens	177-197
16608409-8	2006	Copolymer 1 (Cop 1, glatiramer acetate, Copaxone) is a synthetic amino acid random copolymer that is immunologically cross-reactive with myelin basic protein and suppresses experimental allergic encephalomyelitis in several animal species.	copolymer	0-9	myelin basic protein	Homo sapiens	137-157
16608409-8	2006	Copolymer 1 (Cop 1, glatiramer acetate, Copaxone) is a synthetic amino acid random copolymer that is immunologically cross-reactive with myelin basic protein and suppresses experimental allergic encephalomyelitis in several animal species.	Glatiramer Acetate	13-18	myelin basic protein	Homo sapiens	137-157
16608409-8	2006	Copolymer 1 (Cop 1, glatiramer acetate, Copaxone) is a synthetic amino acid random copolymer that is immunologically cross-reactive with myelin basic protein and suppresses experimental allergic encephalomyelitis in several animal species.	Glatiramer Acetate	20-38	myelin basic protein	Homo sapiens	137-157
16608409-8	2006	Copolymer 1 (Cop 1, glatiramer acetate, Copaxone) is a synthetic amino acid random copolymer that is immunologically cross-reactive with myelin basic protein and suppresses experimental allergic encephalomyelitis in several animal species.	Glatiramer Acetate	40-48	myelin basic protein	Homo sapiens	137-157
16608409-8	2006	Copolymer 1 (Cop 1, glatiramer acetate, Copaxone) is a synthetic amino acid random copolymer that is immunologically cross-reactive with myelin basic protein and suppresses experimental allergic encephalomyelitis in several animal species.	copolymer	83-92	myelin basic protein	Homo sapiens	137-157
16536470-4	2006	The dye INR gave a 3-fold (+200%) change in fluorescence intensity upon maltose binding when conjugated to S337C MBP with a binding constant (K(d)) of 435 microM.	Maltose	72-79	myelin basic protein	Homo sapiens	113-116
16310860-0	2006	Metal-dependent hydrolysis of myelin basic protein by IgGs from the sera of patients with multiple sclerosis.	Metals	0-5	myelin basic protein	Homo sapiens	30-50
16435391-8	2006	In the N19 cell line, aTf stimulated NF-I and NFkappaB activation, but, aside from aTf, only db-cAMP induced mbp transcription.	Bucladesine	93-100	myelin basic protein	Homo sapiens	109-112
16310860-7	2006	Ni(2+)-activated IgGs were separated into distinct MBP-hydrolyzing fractions by chromatography on HiTraptrade mark Chelating Sepharose charged with Ni(2+).	Nickel(2+)	0-6	myelin basic protein	Homo sapiens	51-54
16310860-7	2006	Ni(2+)-activated IgGs were separated into distinct MBP-hydrolyzing fractions by chromatography on HiTraptrade mark Chelating Sepharose charged with Ni(2+).	Sepharose	125-134	myelin basic protein	Homo sapiens	51-54
16310860-8	2006	Detection of Mg(2+)-dependent proteolytic activity in the SDS-PAGE area corresponding only to IgG provided direct evidence that IgG from sera of MS patients possesses metal-dependent human MBP-hydrolyzing activity.	magnesium ion	13-19	myelin basic protein	Homo sapiens	189-192
16310860-8	2006	Detection of Mg(2+)-dependent proteolytic activity in the SDS-PAGE area corresponding only to IgG provided direct evidence that IgG from sera of MS patients possesses metal-dependent human MBP-hydrolyzing activity.	Sodium Dodecyl Sulfate	58-61	myelin basic protein	Homo sapiens	189-192
16310860-8	2006	Detection of Mg(2+)-dependent proteolytic activity in the SDS-PAGE area corresponding only to IgG provided direct evidence that IgG from sera of MS patients possesses metal-dependent human MBP-hydrolyzing activity.	Metals	167-172	myelin basic protein	Homo sapiens	189-192
17406409-5	2006	Conjugation of DHLA-capped QDs to maltose binding protein (MBP), the immunoglobulin-G-binding beta2 domain of streptococcal protein G (PG) and avidin will be described.	dihydrolipoic acid	15-19	myelin basic protein	Homo sapiens	34-57
16480580-0	2006	[Inhibitory effect of human brain myelin basic protein on H2O2-induced apoptosis of human lung cancer cell line YTLMC-90].	Hydrogen Peroxide	58-62	myelin basic protein	Homo sapiens	34-54
16480580-0	2006	[Inhibitory effect of human brain myelin basic protein on H2O2-induced apoptosis of human lung cancer cell line YTLMC-90].	ytlmc-90	112-120	myelin basic protein	Homo sapiens	34-54
16480580-1	2006	BACKGROUND & OBJECTIVE: Human brain myelin basic protein (MBP) distributes in nervous system and other tissues extensively, and can be detected in many kinds of tumor cells, such as lung cancer, breast cancer, and neuroglioma.	Adenosine Monophosphate	12-15	myelin basic protein	Homo sapiens	40-60
16480580-1	2006	BACKGROUND & OBJECTIVE: Human brain myelin basic protein (MBP) distributes in nervous system and other tissues extensively, and can be detected in many kinds of tumor cells, such as lung cancer, breast cancer, and neuroglioma.	Adenosine Monophosphate	12-15	myelin basic protein	Homo sapiens	62-65
16480580-3	2006	This study was to investigate the inhibitory effect of MBP on hydrogen peroxide (H2O2)-induced apoptosis of human lung cancer cell line YTLMC-90.	Hydrogen Peroxide	62-79	myelin basic protein	Homo sapiens	55-58
16480580-3	2006	This study was to investigate the inhibitory effect of MBP on hydrogen peroxide (H2O2)-induced apoptosis of human lung cancer cell line YTLMC-90.	Hydrogen Peroxide	81-85	myelin basic protein	Homo sapiens	55-58
16480580-3	2006	This study was to investigate the inhibitory effect of MBP on hydrogen peroxide (H2O2)-induced apoptosis of human lung cancer cell line YTLMC-90.	ytlmc-90	136-144	myelin basic protein	Homo sapiens	55-58
16480580-11	2006	CONCLUSION: MBP markedly inhibits H2O2 cytotoxicity to YTLMC-90 cells through promoting cell proliferation and antagonizing H2O2-induced apoptosis.	Hydrogen Peroxide	34-38	myelin basic protein	Homo sapiens	12-15
16480580-11	2006	CONCLUSION: MBP markedly inhibits H2O2 cytotoxicity to YTLMC-90 cells through promoting cell proliferation and antagonizing H2O2-induced apoptosis.	ytlmc-90	55-63	myelin basic protein	Homo sapiens	12-15
16480580-11	2006	CONCLUSION: MBP markedly inhibits H2O2 cytotoxicity to YTLMC-90 cells through promoting cell proliferation and antagonizing H2O2-induced apoptosis.	Hydrogen Peroxide	124-128	myelin basic protein	Homo sapiens	12-15
16384549-3	2006	Maltose binding to MBP is known to convert the open form of the protein to the closed form through conformational changes about the hinge region.	Maltose	0-7	myelin basic protein	Homo sapiens	19-22
16384549-5	2006	Hinge mutations that increased maltose affinity the most (and thus presumably close the apo-MBP domain the most) also abrogated switching the most.	Maltose	31-38	myelin basic protein	Homo sapiens	92-95
16384549-6	2006	We provide evidence for a model of RG13 switching in which there exists a threshold conformation between the open to closed form of the MBP domain that divides states that catalyze beta-lactam hydrolysis with different relative rates of acylation and deacylation.	beta-Lactams	181-192	myelin basic protein	Homo sapiens	136-139
16462032-6	2006	On the other hand, simultaneous treatment with 10 nM dexamethasone and 1 muM aminophylline activated the 36-kDa MBP kinase, pro-apoptotic protein kinase in HL-60 cells.	Dexamethasone	53-66	myelin basic protein	Homo sapiens	112-115
16462032-6	2006	On the other hand, simultaneous treatment with 10 nM dexamethasone and 1 muM aminophylline activated the 36-kDa MBP kinase, pro-apoptotic protein kinase in HL-60 cells.	Aminophylline	77-90	myelin basic protein	Homo sapiens	112-115
16462032-7	2006	The activation of 36-kDa MBP kinase by dexamethasone and aminophylline was supported by studies showing an increase in the number of pH2B-positive and apoptotic Jurkat and HL-60 cells upon exposure to these drugs.	Dexamethasone	39-52	myelin basic protein	Homo sapiens	25-28
16462032-7	2006	The activation of 36-kDa MBP kinase by dexamethasone and aminophylline was supported by studies showing an increase in the number of pH2B-positive and apoptotic Jurkat and HL-60 cells upon exposure to these drugs.	Aminophylline	57-70	myelin basic protein	Homo sapiens	25-28
16462032-8	2006	Thus treatment with a combination of dexamethasone and aminophylline accelerates apoptosis of HL-60 cells via activation of 36-kDa MBP kinase and H2B phosphorylation.	Dexamethasone	37-50	myelin basic protein	Homo sapiens	131-134
16462032-8	2006	Thus treatment with a combination of dexamethasone and aminophylline accelerates apoptosis of HL-60 cells via activation of 36-kDa MBP kinase and H2B phosphorylation.	Aminophylline	55-68	myelin basic protein	Homo sapiens	131-134
16336213-9	2006	The major residue in myelin basic protein phosphorylated by ERK8 (Ser-126) was distinct from that phosphorylated by ERK2 (Thr-97), demonstrating that, although ERK8 is a proline-directed protein kinase, its specificity is distinct from ERK1/ERK2.	Serine	66-69	myelin basic protein	Homo sapiens	21-41
16412061-4	2006	We found that, in MS patients, pretreatment with GA significantly decreases the in vitro proliferative effect of DC on lymphocytes as compared to HC and to unpulsed or myelin basic protein (MBP)-pulsed DC from MS patients (P < 0.05).	Glatiramer Acetate	49-51	myelin basic protein	Homo sapiens	168-188
16412061-4	2006	We found that, in MS patients, pretreatment with GA significantly decreases the in vitro proliferative effect of DC on lymphocytes as compared to HC and to unpulsed or myelin basic protein (MBP)-pulsed DC from MS patients (P < 0.05).	Glatiramer Acetate	49-51	myelin basic protein	Homo sapiens	190-193
16401070-9	2006	The effect was much greater than that reported earlier for another charge isomer of MBP, C8, in which six arginines were deiminated to citrulline, resulting in a reduction of net positive charge of 6.	Arginine	106-115	myelin basic protein	Homo sapiens	84-87
16401070-9	2006	The effect was much greater than that reported earlier for another charge isomer of MBP, C8, in which six arginines were deiminated to citrulline, resulting in a reduction of net positive charge of 6.	Citrulline	135-145	myelin basic protein	Homo sapiens	84-87
17406409-5	2006	Conjugation of DHLA-capped QDs to maltose binding protein (MBP), the immunoglobulin-G-binding beta2 domain of streptococcal protein G (PG) and avidin will be described.	dihydrolipoic acid	15-19	myelin basic protein	Homo sapiens	59-62
17406409-6	2006	MBP and PG were modified by genetic fusion with either a charged leucine zipper or a polyhistidine interaction domain.	polyhistidine	85-98	myelin basic protein	Homo sapiens	0-3
16246290-4	2005	The (Lys-Gly)(5)cyclo(75-82)MBP(74-85) was efficiently synthesized by solid-phase synthesis and purified to a high degree, as confirmed by CE analysis in a low-pH (3.0) phosphate buffer and normal polarity.	lysylglycine	5-12	myelin basic protein	Homo sapiens	28-31
16288781-2	2005	Zn(2+) binding by the engineered MBP was thought to require a large conformational change from "open" to "closed", similar to that observed when maltose is bound by the wild-type protein.	Zinc	0-6	myelin basic protein	Homo sapiens	33-36
16288781-2	2005	Zn(2+) binding by the engineered MBP was thought to require a large conformational change from "open" to "closed", similar to that observed when maltose is bound by the wild-type protein.	Maltose	145-152	myelin basic protein	Homo sapiens	33-36
16288781-3	2005	We show that although this re-designed MBP molecule binds Zn(2+) with high affinity as previously reported, it does not adopt a closed conformation in solution as assessed by small-angle X-ray scattering.	Zinc	58-60	myelin basic protein	Homo sapiens	39-42
16288781-4	2005	High-resolution crystallographic studies of the engineered Zn(2+)-binding MBP molecule demonstrate that Zn(2+) is coordinated by residues on the N-terminal lobe only, and therefore Zn(2+) binding does not require the protein to adopt a fully closed conformation.	Zinc	59-61	myelin basic protein	Homo sapiens	74-77
16288781-4	2005	High-resolution crystallographic studies of the engineered Zn(2+)-binding MBP molecule demonstrate that Zn(2+) is coordinated by residues on the N-terminal lobe only, and therefore Zn(2+) binding does not require the protein to adopt a fully closed conformation.	Zinc	104-106	myelin basic protein	Homo sapiens	74-77
16288781-4	2005	High-resolution crystallographic studies of the engineered Zn(2+)-binding MBP molecule demonstrate that Zn(2+) is coordinated by residues on the N-terminal lobe only, and therefore Zn(2+) binding does not require the protein to adopt a fully closed conformation.	Zinc	104-106	myelin basic protein	Homo sapiens	74-77
16246290-0	2005	Synthesis and study of the electrophoretic behavior of mannan conjugates with cyclic peptide analogue of myelin basic protein using lysine-glycine linker.	Mannans	55-61	myelin basic protein	Homo sapiens	105-125
16246290-0	2005	Synthesis and study of the electrophoretic behavior of mannan conjugates with cyclic peptide analogue of myelin basic protein using lysine-glycine linker.	Peptides, Cyclic	78-92	myelin basic protein	Homo sapiens	105-125
16246290-0	2005	Synthesis and study of the electrophoretic behavior of mannan conjugates with cyclic peptide analogue of myelin basic protein using lysine-glycine linker.	Lysine	132-138	myelin basic protein	Homo sapiens	105-125
16246290-0	2005	Synthesis and study of the electrophoretic behavior of mannan conjugates with cyclic peptide analogue of myelin basic protein using lysine-glycine linker.	Glycine	139-146	myelin basic protein	Homo sapiens	105-125
16246290-2	2005	For this purpose, the cyclo(75-82) myelin basic protein (MBP)(74-85) analogue was conjugated to mannan (a polymannose) via (Lys-Gly)(5) linker.	Mannans	96-102	myelin basic protein	Homo sapiens	35-55
16246290-4	2005	The (Lys-Gly)(5)cyclo(75-82)MBP(74-85) was efficiently synthesized by solid-phase synthesis and purified to a high degree, as confirmed by CE analysis in a low-pH (3.0) phosphate buffer and normal polarity.	Phosphates	169-178	myelin basic protein	Homo sapiens	28-31
16246290-2	2005	For this purpose, the cyclo(75-82) myelin basic protein (MBP)(74-85) analogue was conjugated to mannan (a polymannose) via (Lys-Gly)(5) linker.	Mannans	96-102	myelin basic protein	Homo sapiens	57-60
16259003-1	2005	The random amino acid copolymers FYAK and VWAK ameliorate EAE in a humanized mouse model expressing both a human transgenic myelin basic protein (MBP)85-99-specific T cell receptor and HLA-DR2.	amino acid copolymers	11-32	myelin basic protein	Homo sapiens	124-144
16246290-2	2005	For this purpose, the cyclo(75-82) myelin basic protein (MBP)(74-85) analogue was conjugated to mannan (a polymannose) via (Lys-Gly)(5) linker.	polymannose	106-117	myelin basic protein	Homo sapiens	35-55
16246290-2	2005	For this purpose, the cyclo(75-82) myelin basic protein (MBP)(74-85) analogue was conjugated to mannan (a polymannose) via (Lys-Gly)(5) linker.	polymannose	106-117	myelin basic protein	Homo sapiens	57-60
16246290-2	2005	For this purpose, the cyclo(75-82) myelin basic protein (MBP)(74-85) analogue was conjugated to mannan (a polymannose) via (Lys-Gly)(5) linker.	lysylglycine	124-131	myelin basic protein	Homo sapiens	35-55
16246290-2	2005	For this purpose, the cyclo(75-82) myelin basic protein (MBP)(74-85) analogue was conjugated to mannan (a polymannose) via (Lys-Gly)(5) linker.	lysylglycine	124-131	myelin basic protein	Homo sapiens	57-60
16246290-3	2005	Monitoring of synthesis of the (Lys-Gly)(5)-containing cyclic analogue of MBP, mannan oxidation, and the conjugation reaction of this analogue to oxidized mannan was performed with capillary electrophoresis (CE) in operating buffers of different pH values.	(lys-gly)(5)	31-43	myelin basic protein	Homo sapiens	74-77
16259003-1	2005	The random amino acid copolymers FYAK and VWAK ameliorate EAE in a humanized mouse model expressing both a human transgenic myelin basic protein (MBP)85-99-specific T cell receptor and HLA-DR2.	amino acid copolymers	11-32	myelin basic protein	Homo sapiens	146-149
16080185-3	2005	Model proteins consisting of maltose binding protein (MBP) having a C- or N-terminal polyhistidine tag were used.	polyhistidine	85-98	myelin basic protein	Homo sapiens	29-52
16691471-5	2005	For cross-linking studies, unique cysteine residues were introduced into structurally defined sites within the B and C subunits and used as points of attachment for the photoactivated cross-linking reagent MBP.	Cysteine	34-42	myelin basic protein	Homo sapiens	206-209
16080185-3	2005	Model proteins consisting of maltose binding protein (MBP) having a C- or N-terminal polyhistidine tag were used.	polyhistidine	85-98	myelin basic protein	Homo sapiens	54-57
16080185-4	2005	Digestion of the hexahistidine tag of MBP-His(6) by Factor Xa and HT15-MBP by DAPase-1 was successful.	His-His-His-His-His-His	17-30	myelin basic protein	Homo sapiens	38-41
16080185-4	2005	Digestion of the hexahistidine tag of MBP-His(6) by Factor Xa and HT15-MBP by DAPase-1 was successful.	Histidine	42-45	myelin basic protein	Homo sapiens	38-41
16080185-5	2005	The time taken to complete the conversion of MBP-His(6) to MBP was 16 h, as judged by SDS-PAGE and Western blots against anti-His antibody.	Histidine	49-52	myelin basic protein	Homo sapiens	45-48
16080185-5	2005	The time taken to complete the conversion of MBP-His(6) to MBP was 16 h, as judged by SDS-PAGE and Western blots against anti-His antibody.	Histidine	49-52	myelin basic protein	Homo sapiens	59-62
16080185-5	2005	The time taken to complete the conversion of MBP-His(6) to MBP was 16 h, as judged by SDS-PAGE and Western blots against anti-His antibody.	Sodium Dodecyl Sulfate	86-89	myelin basic protein	Homo sapiens	45-48
16080185-5	2005	The time taken to complete the conversion of MBP-His(6) to MBP was 16 h, as judged by SDS-PAGE and Western blots against anti-His antibody.	Sodium Dodecyl Sulfate	86-89	myelin basic protein	Homo sapiens	59-62
16080185-5	2005	The time taken to complete the conversion of MBP-His(6) to MBP was 16 h, as judged by SDS-PAGE and Western blots against anti-His antibody.	Histidine	126-129	myelin basic protein	Homo sapiens	45-48
16080185-5	2005	The time taken to complete the conversion of MBP-His(6) to MBP was 16 h, as judged by SDS-PAGE and Western blots against anti-His antibody.	Histidine	126-129	myelin basic protein	Homo sapiens	59-62
16080185-11	2005	The detagged MBP proteins were isolated from the digestion mixtures using a simple subtractive IMAC column procedure with the detagged protein appearing in the flowthrough and washing fractions while residual dipeptides and DAPase-I (which was engineered to exhibit a poly-His tail) were adsorbed to the column.	Dipeptides	209-219	myelin basic protein	Homo sapiens	13-16
16080185-11	2005	The detagged MBP proteins were isolated from the digestion mixtures using a simple subtractive IMAC column procedure with the detagged protein appearing in the flowthrough and washing fractions while residual dipeptides and DAPase-I (which was engineered to exhibit a poly-His tail) were adsorbed to the column.	Histidine	273-276	myelin basic protein	Homo sapiens	13-16
16562482-3	2005	The fusion protein rAgB-MBP was made up of antigen B and MBP (maltose binding protein) which was designed to absorb the antigen B onto the amylose column.	Amylose	139-146	myelin basic protein	Homo sapiens	24-27
16143635-3	2005	The maltose/maltodextrin-binding protein (MBP) serves as an initial high-affinity binding component in the periplasm that delivers the bound sugar into the cognate ABC transporter MalFGK(2).	Sugars	141-146	myelin basic protein	Homo sapiens	4-40
16143635-3	2005	The maltose/maltodextrin-binding protein (MBP) serves as an initial high-affinity binding component in the periplasm that delivers the bound sugar into the cognate ABC transporter MalFGK(2).	Sugars	141-146	myelin basic protein	Homo sapiens	42-45
15917983-0	2005	Microstructural analysis of the effects of incorporation of myelin basic protein in phospholipid layers.	Phospholipids	84-96	myelin basic protein	Homo sapiens	60-80
15917983-2	2005	We provide for the first time, direct microscopic evidence on the destructuring effects of MBP leading to plasticity of the DPPG layers supporting commonly accepted models of the stabilizing role of MBP in the myelin membrane.	1,2-dipalmitoylphosphatidylglycerol	124-128	myelin basic protein	Homo sapiens	91-94
15917983-2	2005	We provide for the first time, direct microscopic evidence on the destructuring effects of MBP leading to plasticity of the DPPG layers supporting commonly accepted models of the stabilizing role of MBP in the myelin membrane.	1,2-dipalmitoylphosphatidylglycerol	124-128	myelin basic protein	Homo sapiens	199-202
16562482-3	2005	The fusion protein rAgB-MBP was made up of antigen B and MBP (maltose binding protein) which was designed to absorb the antigen B onto the amylose column.	Amylose	139-146	myelin basic protein	Homo sapiens	57-60
16562482-3	2005	The fusion protein rAgB-MBP was made up of antigen B and MBP (maltose binding protein) which was designed to absorb the antigen B onto the amylose column.	Amylose	139-146	myelin basic protein	Homo sapiens	62-85
16040047-1	2005	An immunoadsorbent that removes anti-acetylcholine receptor antibodies (AChRAb) in abnormal serum of myasthenia gravis (MG) patient was efficiently prepared by an expression product, the functional fragment of AChR(alpha205) fused with maltose binding protein (MBP).	Acetylcholine	37-50	myelin basic protein	Homo sapiens	261-264
16113295-4	2005	Recent studies showing that acanthamoebae express a mannose-binding protein (MBP) and that free alpha-mannose (alpha-Man) specifically inhibits the adhesion of parasites to host cells suggest that the MBP plays a key role in the pathogenesis of Acanthamoeba infection by mediating host-parasite interactions.	alpha-D-Mannose	96-109	myelin basic protein	Homo sapiens	201-204
16113295-11	2005	N-Glycanase treatment to remove N-linked oligosaccharides shifted the subunit molecular mass of MBP from 130 kDa to 110 kDa.	n-linked oligosaccharides	32-57	myelin basic protein	Homo sapiens	96-99
16204762-4	2005	Enalapril increased the HCO3- secretion in a dose-dependent manner, with a decrease in arterial blood pressure (MBP), and these effects were significantly attenuated by pretreatment with indomethacin, L-NAME and FR172357 (a selective bradykinin B2 receptor antagonist).	Enalapril	0-9	myelin basic protein	Homo sapiens	112-115
16204762-4	2005	Enalapril increased the HCO3- secretion in a dose-dependent manner, with a decrease in arterial blood pressure (MBP), and these effects were significantly attenuated by pretreatment with indomethacin, L-NAME and FR172357 (a selective bradykinin B2 receptor antagonist).	Indomethacin	187-199	myelin basic protein	Homo sapiens	112-115
16204762-4	2005	Enalapril increased the HCO3- secretion in a dose-dependent manner, with a decrease in arterial blood pressure (MBP), and these effects were significantly attenuated by pretreatment with indomethacin, L-NAME and FR172357 (a selective bradykinin B2 receptor antagonist).	NG-Nitroarginine Methyl Ester	201-207	myelin basic protein	Homo sapiens	112-115
16049372-5	2005	The Ab-dependent hydrolysis of hMBP was analyzed using SDS-PAGE.	Sodium Dodecyl Sulfate	55-58	myelin basic protein	Homo sapiens	31-35
15978327-5	2005	The soluble form of MBP-Ta60b fused scFv could be extracted and affinity-purified with an amylose/agarose column, allowing its immunoreactivity to be analyzed by enzyme-linked immunosorbent assay (ELISA), mixed hemadsorption assay, and fluorescence activated cell sorting.	Amylose	90-97	myelin basic protein	Homo sapiens	20-23
15978327-5	2005	The soluble form of MBP-Ta60b fused scFv could be extracted and affinity-purified with an amylose/agarose column, allowing its immunoreactivity to be analyzed by enzyme-linked immunosorbent assay (ELISA), mixed hemadsorption assay, and fluorescence activated cell sorting.	Sepharose	98-105	myelin basic protein	Homo sapiens	20-23
16171406-6	2005	Since PMSF inhibition suggested a role for a serine residue in the cleavage, we labeled myelin basic protein with diisopropyl fluorophosphate (DFP), known to bind active site serine residues.	Isoflurophate	114-141	myelin basic protein	Homo sapiens	88-108
16171406-6	2005	Since PMSF inhibition suggested a role for a serine residue in the cleavage, we labeled myelin basic protein with diisopropyl fluorophosphate (DFP), known to bind active site serine residues.	Isoflurophate	143-146	myelin basic protein	Homo sapiens	88-108
16171406-6	2005	Since PMSF inhibition suggested a role for a serine residue in the cleavage, we labeled myelin basic protein with diisopropyl fluorophosphate (DFP), known to bind active site serine residues.	Serine	175-181	myelin basic protein	Homo sapiens	88-108
16116208-1	2005	Mannan-binding protein (MBP) is a C-type serum lectin that is known to be a host defense factor involved in innate immunity, and recognizes mannose, fucose, and N-acetylglucosamine residues.	Mannose	140-147	myelin basic protein	Homo sapiens	0-22
16116208-1	2005	Mannan-binding protein (MBP) is a C-type serum lectin that is known to be a host defense factor involved in innate immunity, and recognizes mannose, fucose, and N-acetylglucosamine residues.	Mannose	140-147	myelin basic protein	Homo sapiens	24-27
16116208-1	2005	Mannan-binding protein (MBP) is a C-type serum lectin that is known to be a host defense factor involved in innate immunity, and recognizes mannose, fucose, and N-acetylglucosamine residues.	Fucose	149-155	myelin basic protein	Homo sapiens	0-22
16116208-1	2005	Mannan-binding protein (MBP) is a C-type serum lectin that is known to be a host defense factor involved in innate immunity, and recognizes mannose, fucose, and N-acetylglucosamine residues.	Fucose	149-155	myelin basic protein	Homo sapiens	24-27
16116208-1	2005	Mannan-binding protein (MBP) is a C-type serum lectin that is known to be a host defense factor involved in innate immunity, and recognizes mannose, fucose, and N-acetylglucosamine residues.	Acetylglucosamine	161-180	myelin basic protein	Homo sapiens	0-22
16116208-1	2005	Mannan-binding protein (MBP) is a C-type serum lectin that is known to be a host defense factor involved in innate immunity, and recognizes mannose, fucose, and N-acetylglucosamine residues.	Acetylglucosamine	161-180	myelin basic protein	Homo sapiens	24-27
16116208-6	2005	Deglycosylation experiments indicated that the MBP ligands on meprins are high mannose- or complex-type N-glycans.	Mannose	79-86	myelin basic protein	Homo sapiens	47-50
16116208-6	2005	Deglycosylation experiments indicated that the MBP ligands on meprins are high mannose- or complex-type N-glycans.	n-glycans	104-113	myelin basic protein	Homo sapiens	47-50
16116208-7	2005	The interaction of MBP with meprins resulted in significant decreases in the proteolytic activity and matrix-degrading ability of meprins.	Tiopronin	28-35	myelin basic protein	Homo sapiens	19-22
16116208-8	2005	Our results suggest that core N-linked oligosaccharides on meprins are associated with the optimal enzymatic activity and that MBP is an important regulator for modulation of the localized meprin proteolytic activity via N-glycan binding.	n-glycan	221-229	myelin basic protein	Homo sapiens	127-130
16116208-9	2005	Because meprins are known to be some of the major matrix-degrading metalloproteases in the kidney and intestine, MBP, which functions as a natural and effective inhibitor of meprins, may contribute, as a potential therapeutic target, to tumor progression by facilitating the migration, intravasation, and metastasis of carcinoma cells, and to acute renal failure and inflammatory bowel diseases.	Tiopronin	8-15	myelin basic protein	Homo sapiens	113-116
16040047-2	2005	The ligand can then covalently bind to amylose resin through MBP fusion protein.	Amylose	39-46	myelin basic protein	Homo sapiens	61-64
16122007-9	2005	The sensitivity and specificity of initial NSE and S100B and peak myelin basic protein concentrations for identifying TBI at ROC curve-defined cutoffs were 71 and 64% (NSE), 77 and 72% (S100B), and 44 and 96% (myelin basic protein), respectively.	Thioacetazone	118-121	myelin basic protein	Homo sapiens	66-86
16122007-12	2005	CONCLUSIONS: Serum NSE, S100B, or myelin basic protein are increased in the majority of children with acute nTBI and iTBI, including well-appearing children with iTBI in whom the diagnosis might otherwise have been missed.	itbi	117-121	myelin basic protein	Homo sapiens	34-54
15799691-3	2005	After accumulation of decays at -70 degrees C in the presence of 10% DMSO, there was a non-random distribution of DNA fragments with an excess of fragments <0.5 Mbp and the measured yield was 1.6 DSBs/decay.	Dimethyl Sulfoxide	69-73	myelin basic protein	Homo sapiens	164-167
15930210-9	2005	MBP-OP was attained for 96.3% of patients with DP and 93.7% with EP (responders).	Dopamine	47-49	myelin basic protein	Homo sapiens	0-6
15930210-15	2005	Low-dose EP was as effective as low/moderate-dose DP in increasing MBP among LBW infants.	Dopamine	50-52	myelin basic protein	Homo sapiens	67-70
15704220-7	2005	These include the cationicity of myelin basic protein (MBP) as a result of the action of peptidyl argininedeiminase (PAD) activity converting arginyl residues to citrulline.	Citrulline	162-172	myelin basic protein	Homo sapiens	33-53
15704220-7	2005	These include the cationicity of myelin basic protein (MBP) as a result of the action of peptidyl argininedeiminase (PAD) activity converting arginyl residues to citrulline.	Citrulline	162-172	myelin basic protein	Homo sapiens	55-58
15634673-0	2005	Characterization of oligosaccharide ligands expressed on SW1116 cells recognized by mannan-binding protein.	Oligosaccharides	20-35	myelin basic protein	Homo sapiens	84-106
15634673-2	2005	Mannan-binding protein (MBP) is a C-type serum lectin and activates complement through the lectin pathway when it binds to ligand sugars such as mannose, N-acetylglucosamine, and fucose on microbes.	Sugars	130-136	myelin basic protein	Homo sapiens	0-22
15634673-14	2005	The MBP ligands were shown to be large, multiantennary N-glycans carrying a highly fucosylated polylactosamine type structure.	n-glycans	55-64	myelin basic protein	Homo sapiens	4-7
15634673-2	2005	Mannan-binding protein (MBP) is a C-type serum lectin and activates complement through the lectin pathway when it binds to ligand sugars such as mannose, N-acetylglucosamine, and fucose on microbes.	Sugars	130-136	myelin basic protein	Homo sapiens	24-27
15634673-14	2005	The MBP ligands were shown to be large, multiantennary N-glycans carrying a highly fucosylated polylactosamine type structure.	polylactosamine	95-110	myelin basic protein	Homo sapiens	4-7
15634673-2	2005	Mannan-binding protein (MBP) is a C-type serum lectin and activates complement through the lectin pathway when it binds to ligand sugars such as mannose, N-acetylglucosamine, and fucose on microbes.	Mannose	145-152	myelin basic protein	Homo sapiens	0-22
15634673-2	2005	Mannan-binding protein (MBP) is a C-type serum lectin and activates complement through the lectin pathway when it binds to ligand sugars such as mannose, N-acetylglucosamine, and fucose on microbes.	Mannose	145-152	myelin basic protein	Homo sapiens	24-27
15634673-2	2005	Mannan-binding protein (MBP) is a C-type serum lectin and activates complement through the lectin pathway when it binds to ligand sugars such as mannose, N-acetylglucosamine, and fucose on microbes.	Acetylglucosamine	154-173	myelin basic protein	Homo sapiens	0-22
15634673-2	2005	Mannan-binding protein (MBP) is a C-type serum lectin and activates complement through the lectin pathway when it binds to ligand sugars such as mannose, N-acetylglucosamine, and fucose on microbes.	Acetylglucosamine	154-173	myelin basic protein	Homo sapiens	24-27
15634673-2	2005	Mannan-binding protein (MBP) is a C-type serum lectin and activates complement through the lectin pathway when it binds to ligand sugars such as mannose, N-acetylglucosamine, and fucose on microbes.	Fucose	179-185	myelin basic protein	Homo sapiens	0-22
15634673-2	2005	Mannan-binding protein (MBP) is a C-type serum lectin and activates complement through the lectin pathway when it binds to ligand sugars such as mannose, N-acetylglucosamine, and fucose on microbes.	Fucose	179-185	myelin basic protein	Homo sapiens	24-27
15634673-11	2005	Initial experiments involving plant lectins and anti-Lewis antibodies as inhibitors of MBP binding to SW1116 cells indicated that fucose plays a crucial role in the interaction.	Fucose	130-136	myelin basic protein	Homo sapiens	87-90
15647258-0	2005	Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermolecular disulfide rearrangements.	Disulfides	129-138	myelin basic protein	Homo sapiens	72-75
15647258-4	2005	A comparison of the disulfide structure of the reactants with the known disulfide structure of the PAPP-A.pro-MBP complex reveals that six cysteine residues of the pro-MBP subunit (Cys-51, Cys-89, Cys-104, Cys-107, Cys-128, and Cys-169) and two cysteine residues of the PAPP-A subunit (Cys-381 and Cys-652) change their status from the uncomplexed to the complexed states.	Disulfides	72-81	myelin basic protein	Homo sapiens	110-113
15647258-6	2005	In the PAPP-A.pro-MBP complex, two of these form the basis of both two interchain disulfide bonds between the PAPP-A and the pro-MBP subunits and two disulfide bonds responsible for pro-MBP dimerization, respectively.	Disulfides	82-91	myelin basic protein	Homo sapiens	129-132
15647258-4	2005	A comparison of the disulfide structure of the reactants with the known disulfide structure of the PAPP-A.pro-MBP complex reveals that six cysteine residues of the pro-MBP subunit (Cys-51, Cys-89, Cys-104, Cys-107, Cys-128, and Cys-169) and two cysteine residues of the PAPP-A subunit (Cys-381 and Cys-652) change their status from the uncomplexed to the complexed states.	Proline	106-109	myelin basic protein	Homo sapiens	110-113
15647258-6	2005	In the PAPP-A.pro-MBP complex, two of these form the basis of both two interchain disulfide bonds between the PAPP-A and the pro-MBP subunits and two disulfide bonds responsible for pro-MBP dimerization, respectively.	Disulfides	150-159	myelin basic protein	Homo sapiens	18-21
15647258-6	2005	In the PAPP-A.pro-MBP complex, two of these form the basis of both two interchain disulfide bonds between the PAPP-A and the pro-MBP subunits and two disulfide bonds responsible for pro-MBP dimerization, respectively.	Disulfides	150-159	myelin basic protein	Homo sapiens	129-132
15647258-4	2005	A comparison of the disulfide structure of the reactants with the known disulfide structure of the PAPP-A.pro-MBP complex reveals that six cysteine residues of the pro-MBP subunit (Cys-51, Cys-89, Cys-104, Cys-107, Cys-128, and Cys-169) and two cysteine residues of the PAPP-A subunit (Cys-381 and Cys-652) change their status from the uncomplexed to the complexed states.	Cysteine	139-147	myelin basic protein	Homo sapiens	110-113
15647258-4	2005	A comparison of the disulfide structure of the reactants with the known disulfide structure of the PAPP-A.pro-MBP complex reveals that six cysteine residues of the pro-MBP subunit (Cys-51, Cys-89, Cys-104, Cys-107, Cys-128, and Cys-169) and two cysteine residues of the PAPP-A subunit (Cys-381 and Cys-652) change their status from the uncomplexed to the complexed states.	Cysteine	181-184	myelin basic protein	Homo sapiens	110-113
15647258-6	2005	In the PAPP-A.pro-MBP complex, two of these form the basis of both two interchain disulfide bonds between the PAPP-A and the pro-MBP subunits and two disulfide bonds responsible for pro-MBP dimerization, respectively.	Disulfides	82-91	myelin basic protein	Homo sapiens	18-21
15743189-1	2005	A cyclic analogue, [cyclo(87-99)MBP(87)(-)(99)], of the human immunodominant MBP(87)(-)(99) epitope, was designed based on ROESY/NMR distance information and modeling data for linear epitope 87-99, taking into account T-cell (Phe(89), Lys(91), Pro(96)) and HLA (His(88), Phe(90), Ile(93)) contact side-chain information.	Phenylalanine	226-229	myelin basic protein	Homo sapiens	32-35
15743189-1	2005	A cyclic analogue, [cyclo(87-99)MBP(87)(-)(99)], of the human immunodominant MBP(87)(-)(99) epitope, was designed based on ROESY/NMR distance information and modeling data for linear epitope 87-99, taking into account T-cell (Phe(89), Lys(91), Pro(96)) and HLA (His(88), Phe(90), Ile(93)) contact side-chain information.	Phenylalanine	226-229	myelin basic protein	Homo sapiens	77-80
15736962-0	2005	Effect of arginine loss in myelin basic protein, as occurs in its deiminated charge isoform, on mediation of actin polymerization and actin binding to a lipid membrane in vitro.	Arginine	10-18	myelin basic protein	Homo sapiens	27-47
15736962-3	2005	MBP consists of a number of posttranslationally modified isoforms of varying charge, including C8, in which six arginines are deiminated to the uncharged residue citrulline.	Arginine	112-121	myelin basic protein	Homo sapiens	0-3
15736962-3	2005	MBP consists of a number of posttranslationally modified isoforms of varying charge, including C8, in which six arginines are deiminated to the uncharged residue citrulline.	Citrulline	162-172	myelin basic protein	Homo sapiens	0-3
15743189-1	2005	A cyclic analogue, [cyclo(87-99)MBP(87)(-)(99)], of the human immunodominant MBP(87)(-)(99) epitope, was designed based on ROESY/NMR distance information and modeling data for linear epitope 87-99, taking into account T-cell (Phe(89), Lys(91), Pro(96)) and HLA (His(88), Phe(90), Ile(93)) contact side-chain information.	Lysine	235-238	myelin basic protein	Homo sapiens	32-35
15743189-1	2005	A cyclic analogue, [cyclo(87-99)MBP(87)(-)(99)], of the human immunodominant MBP(87)(-)(99) epitope, was designed based on ROESY/NMR distance information and modeling data for linear epitope 87-99, taking into account T-cell (Phe(89), Lys(91), Pro(96)) and HLA (His(88), Phe(90), Ile(93)) contact side-chain information.	Lysine	235-238	myelin basic protein	Homo sapiens	77-80
15743189-1	2005	A cyclic analogue, [cyclo(87-99)MBP(87)(-)(99)], of the human immunodominant MBP(87)(-)(99) epitope, was designed based on ROESY/NMR distance information and modeling data for linear epitope 87-99, taking into account T-cell (Phe(89), Lys(91), Pro(96)) and HLA (His(88), Phe(90), Ile(93)) contact side-chain information.	Phenylalanine	271-274	myelin basic protein	Homo sapiens	32-35
15743189-1	2005	A cyclic analogue, [cyclo(87-99)MBP(87)(-)(99)], of the human immunodominant MBP(87)(-)(99) epitope, was designed based on ROESY/NMR distance information and modeling data for linear epitope 87-99, taking into account T-cell (Phe(89), Lys(91), Pro(96)) and HLA (His(88), Phe(90), Ile(93)) contact side-chain information.	Phenylalanine	271-274	myelin basic protein	Homo sapiens	77-80
15743189-1	2005	A cyclic analogue, [cyclo(87-99)MBP(87)(-)(99)], of the human immunodominant MBP(87)(-)(99) epitope, was designed based on ROESY/NMR distance information and modeling data for linear epitope 87-99, taking into account T-cell (Phe(89), Lys(91), Pro(96)) and HLA (His(88), Phe(90), Ile(93)) contact side-chain information.	Isoleucine	280-283	myelin basic protein	Homo sapiens	32-35
15743189-1	2005	A cyclic analogue, [cyclo(87-99)MBP(87)(-)(99)], of the human immunodominant MBP(87)(-)(99) epitope, was designed based on ROESY/NMR distance information and modeling data for linear epitope 87-99, taking into account T-cell (Phe(89), Lys(91), Pro(96)) and HLA (His(88), Phe(90), Ile(93)) contact side-chain information.	Isoleucine	280-283	myelin basic protein	Homo sapiens	77-80
15864429-3	2005	Low-temperature cultivation at 13 degrees C during IPTG-induction significantly improved both solubility and MBP-tagging of the recombinant enzyme expressed in bacteria.	Isopropyl Thiogalactoside	51-55	myelin basic protein	Homo sapiens	109-112
15849025-6	2005	A striking exception is a group of myelin-related genes, consisting of multiple transcripts representing myelin basic protein (MBP), proteolipid protein (PLP) and myelin-associated oligodendrocyte basic protein (MOBP), which as a group are substantially decreased in cocaine abusers compared to controls.	Cocaine	267-274	myelin basic protein	Homo sapiens	105-125
15669863-2	2005	Either AlexaFluor 488 or Cy3 dye was attached to maltose binding protein (MBP) and used with various QD acceptors.	alexafluor 488	7-21	myelin basic protein	Homo sapiens	49-72
15669863-2	2005	Either AlexaFluor 488 or Cy3 dye was attached to maltose binding protein (MBP) and used with various QD acceptors.	alexafluor 488	7-21	myelin basic protein	Homo sapiens	74-77
15669863-2	2005	Either AlexaFluor 488 or Cy3 dye was attached to maltose binding protein (MBP) and used with various QD acceptors.	cy3	25-28	myelin basic protein	Homo sapiens	49-72
15669863-2	2005	Either AlexaFluor 488 or Cy3 dye was attached to maltose binding protein (MBP) and used with various QD acceptors.	cy3	25-28	myelin basic protein	Homo sapiens	74-77
15864429-5	2005	The MBP-tagged enzyme was efficiently purified by a combination of cation-exchange column and amylase-conjugated agarose column chromatography.	Sepharose	113-120	myelin basic protein	Homo sapiens	4-7
15665281-6	2005	Immunostaining of myelin basic protein on paraffin sections derived from 18 incompletely resected JPAs suggests that JPA without myelin basic protein-positively stained tumor cells may have a higher tendency to progress.	Paraffin	42-50	myelin basic protein	Homo sapiens	18-38
15576565-7	2005	Multiple modifications were made by reacting an unprotected cysteine in MBP first, deprotecting the zinc finger, and then reacting the zinc finger cysteines.	Cysteine	60-68	myelin basic protein	Homo sapiens	72-75
17150694-1	2005	We examined binding ability of MBP-LOR3(ARF) protein to triplexes composed of branched oligonucleotides possessing a pentaerithritol linker.	Oligonucleotides	87-103	myelin basic protein	Homo sapiens	31-34
17150694-1	2005	We examined binding ability of MBP-LOR3(ARF) protein to triplexes composed of branched oligonucleotides possessing a pentaerithritol linker.	pentaerithritol	117-132	myelin basic protein	Homo sapiens	31-34
17150694-2	2005	It was found that the triplex, which has an antraquinonecarbonyl group at the 5"-end of the third strand and is connected with the pentaerithritol linker, has greater affinity to the MBP-LOR3(ARF) protein than an unmodified triplex.	pentaerithritol	131-146	myelin basic protein	Homo sapiens	183-186
15378653-4	2004	We found that treatment with 4-aminopyridine (4-AP), a broad-spectrum K(+) channel antagonist, results in: (1) decreased number of oligodendroglial progenitors (OP) and OLGs; (2) diminished astrogliosis; and (3) decreased remyelination in the corpus callosum based on the immunoreactivity to myelin basic protein (MBP), Rip monoclonal antibody, and by electron microscopy.	4-Aminopyridine	29-44	myelin basic protein	Homo sapiens	292-312
15378653-4	2004	We found that treatment with 4-aminopyridine (4-AP), a broad-spectrum K(+) channel antagonist, results in: (1) decreased number of oligodendroglial progenitors (OP) and OLGs; (2) diminished astrogliosis; and (3) decreased remyelination in the corpus callosum based on the immunoreactivity to myelin basic protein (MBP), Rip monoclonal antibody, and by electron microscopy.	4-Aminopyridine	29-44	myelin basic protein	Homo sapiens	314-317
15378653-4	2004	We found that treatment with 4-aminopyridine (4-AP), a broad-spectrum K(+) channel antagonist, results in: (1) decreased number of oligodendroglial progenitors (OP) and OLGs; (2) diminished astrogliosis; and (3) decreased remyelination in the corpus callosum based on the immunoreactivity to myelin basic protein (MBP), Rip monoclonal antibody, and by electron microscopy.	4-Aminopyridine	46-50	myelin basic protein	Homo sapiens	292-312
15378653-4	2004	We found that treatment with 4-aminopyridine (4-AP), a broad-spectrum K(+) channel antagonist, results in: (1) decreased number of oligodendroglial progenitors (OP) and OLGs; (2) diminished astrogliosis; and (3) decreased remyelination in the corpus callosum based on the immunoreactivity to myelin basic protein (MBP), Rip monoclonal antibody, and by electron microscopy.	4-Aminopyridine	46-50	myelin basic protein	Homo sapiens	314-317
15308777-3	2004	Copolymer 1 (Cop 1, glatiramer acetate, Copaxone) is a synthetic amino acid random copolymer, immunologically cross-reactive with myelin basic protein and suppresses experimental allergic encephalomyelitis in several animal species.	copolymer	0-9	myelin basic protein	Homo sapiens	130-150
15378614-6	2004	After a transient demyelinating insult with lysolecithin in vitro, the cultures recovered with oligodendrocyte differentiation recapitulating a normal time course; there was initially re-expression of CNPase and MBP during this recovery, and this was followed by MOG.	Lysophosphatidylcholines	44-56	myelin basic protein	Homo sapiens	212-215
15456279-3	2004	In the prototype biosensor, quencher-dye-labeled biotin-linked E. coli maltose binding protein (MBP) bound in a specific orientation to a NeutrAvidin-coated surface is employed as a bioreceptor.	Biotin	49-55	myelin basic protein	Homo sapiens	96-99
15456279-5	2004	After self-assembly, a baseline level of FRET quenching is observed due to specific interaction between the beta-CD of the flexible tether arm and the sugar binding site of MBP, which brings the two dyes into proximity.	betadex	108-115	myelin basic protein	Homo sapiens	173-176
15456279-5	2004	After self-assembly, a baseline level of FRET quenching is observed due to specific interaction between the beta-CD of the flexible tether arm and the sugar binding site of MBP, which brings the two dyes into proximity.	Sugars	151-156	myelin basic protein	Homo sapiens	173-176
15308777-3	2004	Copolymer 1 (Cop 1, glatiramer acetate, Copaxone) is a synthetic amino acid random copolymer, immunologically cross-reactive with myelin basic protein and suppresses experimental allergic encephalomyelitis in several animal species.	Glatiramer Acetate	13-18	myelin basic protein	Homo sapiens	130-150
15308777-3	2004	Copolymer 1 (Cop 1, glatiramer acetate, Copaxone) is a synthetic amino acid random copolymer, immunologically cross-reactive with myelin basic protein and suppresses experimental allergic encephalomyelitis in several animal species.	Glatiramer Acetate	20-38	myelin basic protein	Homo sapiens	130-150
15308777-3	2004	Copolymer 1 (Cop 1, glatiramer acetate, Copaxone) is a synthetic amino acid random copolymer, immunologically cross-reactive with myelin basic protein and suppresses experimental allergic encephalomyelitis in several animal species.	Glatiramer Acetate	40-48	myelin basic protein	Homo sapiens	130-150
15145604-3	2004	A marked and long-lasting decrease in CD3+, CD4+, CD8+ and CD45RA+ blood cells and reduced anti-MBP titers were observed with both pixantrone and MTX.	pixantrone	131-141	myelin basic protein	Homo sapiens	96-99
15296638-6	2004	In the assay, gamma-(33)P-ATP and STK15 were incubated in a myelin basic protein (MBP)-coated FlashPlate(R) to generate a scintillation signal.	gamma-(33)p-atp	14-29	myelin basic protein	Homo sapiens	60-80
15296638-6	2004	In the assay, gamma-(33)P-ATP and STK15 were incubated in a myelin basic protein (MBP)-coated FlashPlate(R) to generate a scintillation signal.	gamma-(33)p-atp	14-29	myelin basic protein	Homo sapiens	82-85
15117936-4	2004	The MBP was isolated by chromatography on the mannose affinity gel.	Mannose	46-53	myelin basic protein	Homo sapiens	4-7
15117936-8	2004	recombinant MBP possesses mannose binding activity, and (ii).	Mannose	26-33	myelin basic protein	Homo sapiens	12-15
15223154-0	2004	The role of Zn in the interplay among Langmuir-Blodgett multilayer and myelin basic protein: a quantitative analysis of XANES spectra.	Zinc	12-14	myelin basic protein	Homo sapiens	71-91
15223154-3	2004	By this method, we have been able to correlate the relevant differences between the spectra observed in the XANES range with the coordination changes due to reduction of the space around the Zinc when the level of hydration is lowered and/or the myelin basic protein is added.	xanes	108-113	myelin basic protein	Homo sapiens	246-266
15223154-5	2004	With this investigation, we give an unambiguous answer to the question of the role of zinc in such complexes by showing that the metal interacts with both the phospholipid heads of the substrate and the myelin basic protein.	Metals	129-134	myelin basic protein	Homo sapiens	203-223
15060079-1	2004	Serum mannose-binding protein (MBP) neutralizes invading microorganisms by binding to cell surface carbohydrates and activating MBP-associated serine proteases-1, -2, and -3 (MASPs).	Carbohydrates	99-112	myelin basic protein	Homo sapiens	6-29
15060079-1	2004	Serum mannose-binding protein (MBP) neutralizes invading microorganisms by binding to cell surface carbohydrates and activating MBP-associated serine proteases-1, -2, and -3 (MASPs).	Carbohydrates	99-112	myelin basic protein	Homo sapiens	31-34
15060079-5	2004	First, MBP stimulates MASP-2 autoactivation by increasing the rate of autocatalysis when MBP.MASP-2 complexes bind to a glycan-coated surface.	Polysaccharides	120-126	myelin basic protein	Homo sapiens	7-10
15060079-5	2004	First, MBP stimulates MASP-2 autoactivation by increasing the rate of autocatalysis when MBP.MASP-2 complexes bind to a glycan-coated surface.	Polysaccharides	120-126	myelin basic protein	Homo sapiens	89-92
14962940-9	2004	It appears that copper-binding capabilities are identified with a confidence >90% when the percentage of identical amino acids aligned around the MBP by PHI-BLAST is at least 20% with respect to the entire protein domain length.	Copper	16-22	myelin basic protein	Homo sapiens	149-152
15145604-3	2004	A marked and long-lasting decrease in CD3+, CD4+, CD8+ and CD45RA+ blood cells and reduced anti-MBP titers were observed with both pixantrone and MTX.	Mitoxantrone	146-149	myelin basic protein	Homo sapiens	96-99
15251330-13	2004	CONCLUSIONS: Diurnal and 24-hour periods of ABPM showed significant changes in SBP, DBP, and MBP after active treatment with doxazosin GITS.	Doxazosin	125-134	myelin basic protein	Homo sapiens	93-96
15042587-11	2004	The action of aTf on MBP gene expression in the least mature line is likely to be mediated by the cAMP pathway.	Cyclic AMP	98-102	myelin basic protein	Homo sapiens	21-24
15135394-9	2004	We describe a scheme for expression and simple metal-affinity based purification of MBP-p18Bax.	Metals	47-52	myelin basic protein	Homo sapiens	84-87
15100291-1	2004	The asparagine-specific endoprotease (AEP) controls lysosomal processing of the potential autoantigen myelin basic protein (MBP) by human B lymphoblastoid cells, a feature implicated in the immunopathogenesis of multiple sclerosis.	Asparagine	4-14	myelin basic protein	Homo sapiens	102-122
15100291-1	2004	The asparagine-specific endoprotease (AEP) controls lysosomal processing of the potential autoantigen myelin basic protein (MBP) by human B lymphoblastoid cells, a feature implicated in the immunopathogenesis of multiple sclerosis.	Asparagine	4-14	myelin basic protein	Homo sapiens	124-127
15079863-7	2004	Myelin oligodendrocyte glycoprotein (MOG), proteolipid protein (PLP), MAPK, and some phosphotyrosine-containing proteins were found to co-cluster with GalC and MBP, but myelin-associated glycoprotein (MAG) and phosphatidylinositol-4,5-bisphosphate (PIP(2)) did not.	Phosphatidylinositol 4,5-Diphosphate	210-247	myelin basic protein	Homo sapiens	160-163
15079863-7	2004	Myelin oligodendrocyte glycoprotein (MOG), proteolipid protein (PLP), MAPK, and some phosphotyrosine-containing proteins were found to co-cluster with GalC and MBP, but myelin-associated glycoprotein (MAG) and phosphatidylinositol-4,5-bisphosphate (PIP(2)) did not.	piperidine	249-252	myelin basic protein	Homo sapiens	160-163
14711813-4	2004	Both the autophosphorylation and kinase activity of myelin basic protein as an external substrate of the recombinant RET protein were substantially elevated in the presence of ATP without stimulation by a glial cell line-derived neurotrophic factor, a natural ligand for RET.	Adenosine Triphosphate	176-179	myelin basic protein	Homo sapiens	52-72
14991617-0	2004	Ex vivo detection of myelin basic protein-reactive T cells in multiple sclerosis and controls using specific TCR oligonucleotide probes.	Oligonucleotides	113-128	myelin basic protein	Homo sapiens	21-41
14724269-6	2004	The two most common naturally occurring mutations in MBP result in substitution of acidic amino acids for glycine residues in Gly-X-Y triplets on the N-terminal side of the hinge.	Glycine	106-113	myelin basic protein	Homo sapiens	53-56
14724269-6	2004	The two most common naturally occurring mutations in MBP result in substitution of acidic amino acids for glycine residues in Gly-X-Y triplets on the N-terminal side of the hinge.	Glycine	126-129	myelin basic protein	Homo sapiens	53-56
14760016-6	2004	There were suggestive negative associations between MBP and VSL (-3.07 microm/s, -2.87 microm/s; P =.08) and VCL (-3.25 microm/s, -3.46 microm/s; P =.2), and between MEHP with VSL (-1.09 microm/s, -2.73 microm/s; P =.1) and VCL (-0.29 microm/s, -2.93 microm/s; P =.3).	mono-(2-ethylhexyl)phthalate	166-170	myelin basic protein	Homo sapiens	52-55
15302911-5	2004	In this paper, we investigate the impact of oxidative damage to a methyl-CpG site on MBP binding by the selective placement of 8-oxoguanine (8-oxoG) and 5-hydroxymethylcytosine (HmC) in a MBP recognition sequence.	8-hydroxyguanine	127-139	myelin basic protein	Homo sapiens	85-88
15302911-5	2004	In this paper, we investigate the impact of oxidative damage to a methyl-CpG site on MBP binding by the selective placement of 8-oxoguanine (8-oxoG) and 5-hydroxymethylcytosine (HmC) in a MBP recognition sequence.	8-hydroxyguanine	141-147	myelin basic protein	Homo sapiens	85-88
15302911-5	2004	In this paper, we investigate the impact of oxidative damage to a methyl-CpG site on MBP binding by the selective placement of 8-oxoguanine (8-oxoG) and 5-hydroxymethylcytosine (HmC) in a MBP recognition sequence.	5-hydroxymethylcytosine	153-176	myelin basic protein	Homo sapiens	85-88
15302911-5	2004	In this paper, we investigate the impact of oxidative damage to a methyl-CpG site on MBP binding by the selective placement of 8-oxoguanine (8-oxoG) and 5-hydroxymethylcytosine (HmC) in a MBP recognition sequence.	5-hydroxymethylcytosine	178-181	myelin basic protein	Homo sapiens	85-88
14709096-2	2004	Engineered maltose binding protein (MBP) appended with an oligohistidine tail and labeled with an acceptor dye (Cy3) was immobilized on the nanocrystals via a noncovalent self-assembly scheme.	cy3	112-115	myelin basic protein	Homo sapiens	36-39
14743441-7	2004	In addition, RA-treated CD133+ cells expressed cell type-specific markers for oligodendrocytes including myelin basic protein (MBP) as shown by RT-PCR, proteolipid protein (PLP) by Western blot analysis, and cyclic nucleotide phosphodiesterase (CNPase) by immunostaining.	Tretinoin	13-15	myelin basic protein	Homo sapiens	105-125
14594813-6	2004	ChaK1-cat is able to undergo autophosphorylation and to phosphorylate myelin basic protein and histone H3 on serine and threonine residues.	Serine	109-115	myelin basic protein	Homo sapiens	70-90
14594813-6	2004	ChaK1-cat is able to undergo autophosphorylation and to phosphorylate myelin basic protein and histone H3 on serine and threonine residues.	Threonine	120-129	myelin basic protein	Homo sapiens	70-90
14751262-3	2004	The small size of CaM hinders its immobilization in low-weight-percentage agarose gels; however, fusion of CaM to MBP via a flexible linker provides sufficient restriction of translational mobility in 1% agarose gels.	Sepharose	204-211	myelin basic protein	Homo sapiens	114-117
14751262-4	2004	Cysteine residues were engineered into MBP.CaM (MBP-T34C,T110C-CaM) and labeled with donor and acceptor fluorescent probes yielding a construct (MBP.CaM-DA) which can be used for single-molecule single-pair fluorescence resonance energy transfer (spFRET) experiments.	Cysteine	0-8	myelin basic protein	Homo sapiens	39-42
14751262-4	2004	Cysteine residues were engineered into MBP.CaM (MBP-T34C,T110C-CaM) and labeled with donor and acceptor fluorescent probes yielding a construct (MBP.CaM-DA) which can be used for single-molecule single-pair fluorescence resonance energy transfer (spFRET) experiments.	Cysteine	0-8	myelin basic protein	Homo sapiens	48-51
14751262-4	2004	Cysteine residues were engineered into MBP.CaM (MBP-T34C,T110C-CaM) and labeled with donor and acceptor fluorescent probes yielding a construct (MBP.CaM-DA) which can be used for single-molecule single-pair fluorescence resonance energy transfer (spFRET) experiments.	Cysteine	0-8	myelin basic protein	Homo sapiens	48-51
14743441-7	2004	In addition, RA-treated CD133+ cells expressed cell type-specific markers for oligodendrocytes including myelin basic protein (MBP) as shown by RT-PCR, proteolipid protein (PLP) by Western blot analysis, and cyclic nucleotide phosphodiesterase (CNPase) by immunostaining.	Tretinoin	13-15	myelin basic protein	Homo sapiens	127-130
14680402-4	2004	Whereas double-strand breaks in photon-irradiated cells were randomly distributed, irradiation of intact K562 cells with high-LET nitrogen ions produced an excess of non-randomly distributed DNA fragments 10 kb-1 Mbp in size.	Nitrogen	130-138	myelin basic protein	Homo sapiens	213-216
15467404-0	2004	Superoxide production from human polymorphonuclear leukocytes by human mannan-binding protein (MBP).	Superoxides	0-10	myelin basic protein	Homo sapiens	71-93
15467404-0	2004	Superoxide production from human polymorphonuclear leukocytes by human mannan-binding protein (MBP).	Superoxides	0-10	myelin basic protein	Homo sapiens	95-98
15467404-2	2004	In this study, we found that ligand-bound MBP stimulates polymorphonuclear leukocytes (PMN) to induce cell aggregation and superoxide production.	Superoxides	123-133	myelin basic protein	Homo sapiens	42-45
15467404-4	2004	The PMN aggregation and superoxide production induced by ligand-bound MBP was blocked completely by pertussis toxin, and partially blocked by a platelet activation factor receptor antagonist, TCV-309.	Superoxides	24-34	myelin basic protein	Homo sapiens	70-73
15467404-4	2004	The PMN aggregation and superoxide production induced by ligand-bound MBP was blocked completely by pertussis toxin, and partially blocked by a platelet activation factor receptor antagonist, TCV-309.	TCV 309	192-199	myelin basic protein	Homo sapiens	70-73
14688327-2	2004	By coimmunoprecipitation, we found that MBP is associated with hsp70 in APC in an ATP/ADP-dependent manner.	Adenosine Triphosphate	82-85	myelin basic protein	Homo sapiens	40-43
14688327-2	2004	By coimmunoprecipitation, we found that MBP is associated with hsp70 in APC in an ATP/ADP-dependent manner.	Adenosine Diphosphate	86-89	myelin basic protein	Homo sapiens	40-43
14695288-2	2004	The water-soluble LF-MBP, extracted at pH < 3.0 from defatted brain, is the classical preparation of MBP, commonly regarded as an intrinsically unfolded protein.	Water	4-9	myelin basic protein	Homo sapiens	21-24
14695288-2	2004	The water-soluble LF-MBP, extracted at pH < 3.0 from defatted brain, is the classical preparation of MBP, commonly regarded as an intrinsically unfolded protein.	Water	4-9	myelin basic protein	Homo sapiens	104-107
15002660-3	2004	Using the method of exogenous substrate phosphorylation, we characterised the calcium-dependent and calmodulin-independent protein kinase (CDPK) activity and the myelin basic protein (MBP)-phosphoralating activity that could be due to a mitogen-activated protein kinase (MAPK)-like activity in the developing mesocarp of grape berry.	mesocarp	309-317	myelin basic protein	Homo sapiens	162-182
15002660-3	2004	Using the method of exogenous substrate phosphorylation, we characterised the calcium-dependent and calmodulin-independent protein kinase (CDPK) activity and the myelin basic protein (MBP)-phosphoralating activity that could be due to a mitogen-activated protein kinase (MAPK)-like activity in the developing mesocarp of grape berry.	mesocarp	309-317	myelin basic protein	Homo sapiens	184-187
14592460-1	2003	The association of myelin basic protein charge isomers with the lipid part of the myelin membrane was investigated at the microscopic (molecular) level in a model membrane system, using optical waveguide lightmode spectrometry to determine with high precision the kinetics of association and dissociation to planar phospholipid membranes under controlled hydrodynamic conditions and over a range of protein concentrations.	Phospholipids	315-327	myelin basic protein	Homo sapiens	19-39
15180092-11	2004	The third study shows that low serum levels of the complement-activating serum lectin, mannan (mannose) binding protein (lectin) (MBP = MBL), are associated with a higher erythrocyte sedimentation rate (ESR) (p=0.006), joint swelling score (JS score) (p=0.019), limitation of joint motion score (LM score) (p=0.027), and annual increase in radiographic destruction score (R score) (p=0.053).	Mannans	87-93	myelin basic protein	Homo sapiens	130-133
15180092-11	2004	The third study shows that low serum levels of the complement-activating serum lectin, mannan (mannose) binding protein (lectin) (MBP = MBL), are associated with a higher erythrocyte sedimentation rate (ESR) (p=0.006), joint swelling score (JS score) (p=0.019), limitation of joint motion score (LM score) (p=0.027), and annual increase in radiographic destruction score (R score) (p=0.053).	Mannose	95-102	myelin basic protein	Homo sapiens	130-133
14530390-1	2003	Maltose-binding protein (MBP) is a two-domain protein that undergoes a ligand-mediated conformational rearrangement from an "open" to a "closed" structure on binding to maltooligosaccharides.	maltooligosaccharides	169-190	myelin basic protein	Homo sapiens	0-23
14666735-1	2003	Mannan-binding protein (MBP) is a C-type lectin, which binds to carbohydrates on the surface of some microorganisms and kills them through the activation of complement.	Carbohydrates	64-77	myelin basic protein	Homo sapiens	0-22
14666735-1	2003	Mannan-binding protein (MBP) is a C-type lectin, which binds to carbohydrates on the surface of some microorganisms and kills them through the activation of complement.	Carbohydrates	64-77	myelin basic protein	Homo sapiens	24-27
14732933-3	2003	The mode of action of GA is by initial strong promiscuous binding to major histocompatibility complex class II molecules and competition with MBP and other myelin proteins for such binding and presentation to T cells.	Glatiramer Acetate	22-24	myelin basic protein	Homo sapiens	142-145
14530390-1	2003	Maltose-binding protein (MBP) is a two-domain protein that undergoes a ligand-mediated conformational rearrangement from an "open" to a "closed" structure on binding to maltooligosaccharides.	maltooligosaccharides	169-190	myelin basic protein	Homo sapiens	25-28
14500673-12	2003	We conclude that MBP stimulates a Src kinase-dependent activation of class I(A) PI3K and, in turn, activation of PKCzeta in neutrophils, which contributes to the activation of NADPH oxidase and the resultant O(2)(-) production in response to MBP stimulation.	Superoxides	208-215	myelin basic protein	Homo sapiens	17-20
14555231-3	2003	More than 1 Mbp giant DNA, 200-800 or 50-300 kbp high molecular weight (HMW) DNA and internucleosomal DNA fragments are produced by oxidative stress and by some agents producing ROS during apoptosis or necrosis in several types of mammalian cells.	Reactive Oxygen Species	178-181	myelin basic protein	Homo sapiens	12-15
14522583-0	2003	The requirement of ammonium or other cations linked with p-cresol sulfate for cross-reactivity with a peptide of myelin basic protein.	Ammonium Compounds	19-27	myelin basic protein	Homo sapiens	113-133
14522583-0	2003	The requirement of ammonium or other cations linked with p-cresol sulfate for cross-reactivity with a peptide of myelin basic protein.	4-cresol sulfate	57-73	myelin basic protein	Homo sapiens	113-133
14500673-1	2003	Eosinophil major basic protein (MBP) is an effective stimulus for neutrophil superoxide (O(2)(-)) production, degranulation, and IL-8 production.	Superoxides	77-87	myelin basic protein	Homo sapiens	32-35
12927787-8	2003	Mutation of the ATP-binding Lys-33 to arginine and the Thr-Glu-Tyr motif to Ala-Glu-Phe abolished its ability to phosphorylate myelin basic protein.	Adenosine Triphosphate	16-19	myelin basic protein	Homo sapiens	127-147
14500673-1	2003	Eosinophil major basic protein (MBP) is an effective stimulus for neutrophil superoxide (O(2)(-)) production, degranulation, and IL-8 production.	Superoxides	89-93	myelin basic protein	Homo sapiens	32-35
14500673-4	2003	Measurement of Akt phosphorylation at Ser(473) and Thr(308) confirmed that MBP stimulated PI3K activity and also demonstrated indirectly activation of phosphoinositide-dependent kinase-1 by MBP.	Serine	38-41	myelin basic protein	Homo sapiens	75-78
14500673-4	2003	Measurement of Akt phosphorylation at Ser(473) and Thr(308) confirmed that MBP stimulated PI3K activity and also demonstrated indirectly activation of phosphoinositide-dependent kinase-1 by MBP.	Threonine	51-54	myelin basic protein	Homo sapiens	75-78
14500673-5	2003	Genistein and the Src kinase family inhibitor, 4-amino-5-(4-methyphenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine, inhibited MBP-stimulated phosphorylation of Akt.	Genistein	0-9	myelin basic protein	Homo sapiens	121-124
14500673-5	2003	Genistein and the Src kinase family inhibitor, 4-amino-5-(4-methyphenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine, inhibited MBP-stimulated phosphorylation of Akt.	4-amino-5-(4-methyphenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine	47-109	myelin basic protein	Homo sapiens	121-124
14500673-6	2003	4-Amino-5-(4-methyphenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine also inhibited MBP-stimulated O(2)(-) production.	4-amino-5-(4-methyphenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine	0-62	myelin basic protein	Homo sapiens	78-81
14500673-8	2003	Inhibition of protein kinase Czeta (PKCzeta) inhibited MBP-stimulated O(2)(-) production.	Superoxides	70-75	myelin basic protein	Homo sapiens	55-58
12794084-1	2003	The affinity of maltose-binding protein (MBP) for maltose and related carbohydrates was greatly increased by removal of groups in the interface opposite the ligand binding cleft.	Maltose	16-23	myelin basic protein	Homo sapiens	41-44
12794084-1	2003	The affinity of maltose-binding protein (MBP) for maltose and related carbohydrates was greatly increased by removal of groups in the interface opposite the ligand binding cleft.	Carbohydrates	70-83	myelin basic protein	Homo sapiens	16-39
12794084-1	2003	The affinity of maltose-binding protein (MBP) for maltose and related carbohydrates was greatly increased by removal of groups in the interface opposite the ligand binding cleft.	Carbohydrates	70-83	myelin basic protein	Homo sapiens	41-44
12940738-5	2003	The splicing product MBP-His was detected by Western blotting and immunoprecipitation in cells treated with rapamycin or a nontoxic analogue thereof.	Histidine	25-28	myelin basic protein	Homo sapiens	21-24
12940738-5	2003	The splicing product MBP-His was detected by Western blotting and immunoprecipitation in cells treated with rapamycin or a nontoxic analogue thereof.	Sirolimus	108-117	myelin basic protein	Homo sapiens	21-24
13129393-1	2003	A fluorescence resonance energy-transfer (FRET) sensing system for maltose based on E. coli maltose binding protein (MBP) is demonstrated.	Maltose	67-74	myelin basic protein	Homo sapiens	92-115
13129393-1	2003	A fluorescence resonance energy-transfer (FRET) sensing system for maltose based on E. coli maltose binding protein (MBP) is demonstrated.	Maltose	67-74	myelin basic protein	Homo sapiens	117-120
13129393-4	2003	Binding of the modified beta-CD to dye-conjugated MBP results in assembly of the FRET complex.	betadex	24-31	myelin basic protein	Homo sapiens	50-53
13129393-6	2003	In the use of these FRET pairs, MBP dissociation values for maltose were estimated (0.14-2.90 microM).	Maltose	60-67	myelin basic protein	Homo sapiens	32-35
12927787-8	2003	Mutation of the ATP-binding Lys-33 to arginine and the Thr-Glu-Tyr motif to Ala-Glu-Phe abolished its ability to phosphorylate myelin basic protein.	Threonine	55-58	myelin basic protein	Homo sapiens	127-147
12927787-8	2003	Mutation of the ATP-binding Lys-33 to arginine and the Thr-Glu-Tyr motif to Ala-Glu-Phe abolished its ability to phosphorylate myelin basic protein.	Glutamic Acid	59-62	myelin basic protein	Homo sapiens	127-147
12927787-8	2003	Mutation of the ATP-binding Lys-33 to arginine and the Thr-Glu-Tyr motif to Ala-Glu-Phe abolished its ability to phosphorylate myelin basic protein.	Tyrosine	63-66	myelin basic protein	Homo sapiens	127-147
12927787-8	2003	Mutation of the ATP-binding Lys-33 to arginine and the Thr-Glu-Tyr motif to Ala-Glu-Phe abolished its ability to phosphorylate myelin basic protein.	alanylglutamic acid	76-83	myelin basic protein	Homo sapiens	127-147
12927787-8	2003	Mutation of the ATP-binding Lys-33 to arginine and the Thr-Glu-Tyr motif to Ala-Glu-Phe abolished its ability to phosphorylate myelin basic protein.	Phenylalanine	84-87	myelin basic protein	Homo sapiens	127-147
12957486-7	2003	However, p38 inhibition interfered with an early stage in myelination, thereby preventing ascorbate-induced increases in the levels of mRNAs encoding MBP, MAG, and P(0) and reducing laminin deposition.	Ascorbic Acid	90-99	myelin basic protein	Homo sapiens	150-153
12892735-7	2003	Finally, 19% of pSS, 30% of SLE, and 38% of RA sera reacted with the hMBP.	pss	16-19	myelin basic protein	Homo sapiens	69-73
12942071-3	2003	In these assemblies, multiple copies of Escherichia coli maltose-binding protein (MBP) coordinate to each QD by a C-terminal oligohistidine segment and function as sugar receptors.	oligohistidine	125-139	myelin basic protein	Homo sapiens	82-85
12942071-5	2003	In one configuration, a beta-cyclodextrin-QSY9 dark quencher conjugate bound in the MBP saccharide binding site results in fluorescence resonance energy-transfer (FRET) quenching of QD photoluminescence.	betadex	24-41	myelin basic protein	Homo sapiens	84-87
12942071-5	2003	In one configuration, a beta-cyclodextrin-QSY9 dark quencher conjugate bound in the MBP saccharide binding site results in fluorescence resonance energy-transfer (FRET) quenching of QD photoluminescence.	Carbohydrates	88-98	myelin basic protein	Homo sapiens	84-87
12942071-7	2003	A second maltose sensor assembly consists of QDs coupled with Cy3-labelled MBP bound to beta-cyclodextrin-Cy3.5.	Maltose	9-16	myelin basic protein	Homo sapiens	75-78
12942071-7	2003	A second maltose sensor assembly consists of QDs coupled with Cy3-labelled MBP bound to beta-cyclodextrin-Cy3.5.	cy3	62-65	myelin basic protein	Homo sapiens	75-78
12942071-7	2003	A second maltose sensor assembly consists of QDs coupled with Cy3-labelled MBP bound to beta-cyclodextrin-Cy3.5.	betadex	88-105	myelin basic protein	Homo sapiens	75-78
12942071-7	2003	A second maltose sensor assembly consists of QDs coupled with Cy3-labelled MBP bound to beta-cyclodextrin-Cy3.5.	cy3	106-109	myelin basic protein	Homo sapiens	75-78
12824496-1	2003	The effects of deimination (conversion of arginyl to citrullinyl residues) of myelin basic protein (MBP) on its binding to calmodulin (CaM) have been examined.	citrullinyl	53-64	myelin basic protein	Homo sapiens	78-98
12847249-5	2003	In the ELISAs, the MBP-ghA bound to heat-aggregated IgG and IgM as well as to the HIV-1 gp41 peptide; the MBP-ghB bound preferentially to IgG rather than IgM, in addition to binding beta-amyloid peptide, whereas the MBP-ghC showed a preference for IgM and the HTLV-I gp21 peptide.	4-hydroxybutyric acid	110-113	myelin basic protein	Homo sapiens	106-109
12847249-5	2003	In the ELISAs, the MBP-ghA bound to heat-aggregated IgG and IgM as well as to the HIV-1 gp41 peptide; the MBP-ghB bound preferentially to IgG rather than IgM, in addition to binding beta-amyloid peptide, whereas the MBP-ghC showed a preference for IgM and the HTLV-I gp21 peptide.	4-hydroxybutyric acid	110-113	myelin basic protein	Homo sapiens	106-109
12847249-7	2003	However, for IgM-coated erythrocytes, MBP-ghC was a better inhibitor of C1q than MBP-ghB.	4-hydroxybutyric acid	85-88	myelin basic protein	Homo sapiens	81-84
12824496-1	2003	The effects of deimination (conversion of arginyl to citrullinyl residues) of myelin basic protein (MBP) on its binding to calmodulin (CaM) have been examined.	citrullinyl	53-64	myelin basic protein	Homo sapiens	100-103
12805303-3	2003	The three classic proteolytic activities of the proteasome were significantly decreased in the lactacystin-treated cultures, and the immunocytochemical analysis showed an increase in the number of O4-, O1-, myelin basic protein-, and myelin proteolipid protein-positive cells and a decrease in A2B5-reacting cells.	lactacystin	95-106	myelin basic protein	Homo sapiens	207-240
12749029-6	2003	In addition, endogenous [(32)P]ADP-ribosylation of an exogenous substrate, myelin basic protein, was similar in BD and comparison subject temporal cortex.	[(32)p]adp	24-34	myelin basic protein	Homo sapiens	75-95
12628002-3	2003	ERK5cat phosphorylated at Thr(219), but not Tyr(221), possessed 10% of the activity of the doubly phosphorylated protein towards myelin basic protein, whereas ERK5cat phosphorylated at Tyr(221) alone was much less active.	Threonine	26-29	myelin basic protein	Homo sapiens	129-149
12733908-4	2003	The (H)C(CA)NH-COSY scheme is tested on an (15)N,(13)C,(2)H-[Leu, Val, Ile (delta 1 only)]-methyl-protonated maltose binding protein (MBP)/beta-cyclodextrin complex at 5 degrees C (molecular tumbling time 46 +/- 2 ns), facilitating the assignment of (13)C(delta 1) chemical shifts for 18 of the 19 Ile residues for which backbone assignments were previously obtained.	Leucine	61-64	myelin basic protein	Homo sapiens	109-132
12733908-4	2003	The (H)C(CA)NH-COSY scheme is tested on an (15)N,(13)C,(2)H-[Leu, Val, Ile (delta 1 only)]-methyl-protonated maltose binding protein (MBP)/beta-cyclodextrin complex at 5 degrees C (molecular tumbling time 46 +/- 2 ns), facilitating the assignment of (13)C(delta 1) chemical shifts for 18 of the 19 Ile residues for which backbone assignments were previously obtained.	Leucine	61-64	myelin basic protein	Homo sapiens	134-137
12733908-4	2003	The (H)C(CA)NH-COSY scheme is tested on an (15)N,(13)C,(2)H-[Leu, Val, Ile (delta 1 only)]-methyl-protonated maltose binding protein (MBP)/beta-cyclodextrin complex at 5 degrees C (molecular tumbling time 46 +/- 2 ns), facilitating the assignment of (13)C(delta 1) chemical shifts for 18 of the 19 Ile residues for which backbone assignments were previously obtained.	Valine	66-69	myelin basic protein	Homo sapiens	109-132
12733908-4	2003	The (H)C(CA)NH-COSY scheme is tested on an (15)N,(13)C,(2)H-[Leu, Val, Ile (delta 1 only)]-methyl-protonated maltose binding protein (MBP)/beta-cyclodextrin complex at 5 degrees C (molecular tumbling time 46 +/- 2 ns), facilitating the assignment of (13)C(delta 1) chemical shifts for 18 of the 19 Ile residues for which backbone assignments were previously obtained.	Isoleucine	71-74	myelin basic protein	Homo sapiens	109-132
12733908-4	2003	The (H)C(CA)NH-COSY scheme is tested on an (15)N,(13)C,(2)H-[Leu, Val, Ile (delta 1 only)]-methyl-protonated maltose binding protein (MBP)/beta-cyclodextrin complex at 5 degrees C (molecular tumbling time 46 +/- 2 ns), facilitating the assignment of (13)C(delta 1) chemical shifts for 18 of the 19 Ile residues for which backbone assignments were previously obtained.	betadex	139-156	myelin basic protein	Homo sapiens	109-132
12725872-2	2003	The drug is a synthetic copolymer with an amino acid composition based on the structure of myelin basic protein, one of the autoantigens implicated in the pathogenesis of MS and experimental autoimmune encephalomyelitis (EAE).	copolymer	24-33	myelin basic protein	Homo sapiens	91-111
12691753-0	2003	Structural characterization of a mannose-binding protein-trimannoside complex using residual dipolar couplings.	Methyl 3,6-di-O-(A-D-mannopyranosyl)-A-D-mannopyranoside	57-69	myelin basic protein	Homo sapiens	33-56
12691753-4	2003	The bound ligand geometry and orientational constraints allowed docking of the trimannoside ligand in the binding site of MBP to produce a structural model for MBP-oligosaccharide interactions.	Methyl 3,6-di-O-(A-D-mannopyranosyl)-A-D-mannopyranoside	79-91	myelin basic protein	Homo sapiens	122-125
12691753-4	2003	The bound ligand geometry and orientational constraints allowed docking of the trimannoside ligand in the binding site of MBP to produce a structural model for MBP-oligosaccharide interactions.	Methyl 3,6-di-O-(A-D-mannopyranosyl)-A-D-mannopyranoside	79-91	myelin basic protein	Homo sapiens	160-163
12691753-4	2003	The bound ligand geometry and orientational constraints allowed docking of the trimannoside ligand in the binding site of MBP to produce a structural model for MBP-oligosaccharide interactions.	Oligosaccharides	164-179	myelin basic protein	Homo sapiens	122-125
12691753-4	2003	The bound ligand geometry and orientational constraints allowed docking of the trimannoside ligand in the binding site of MBP to produce a structural model for MBP-oligosaccharide interactions.	Oligosaccharides	164-179	myelin basic protein	Homo sapiens	160-163
12682013-7	2003	During early myelin development, tyrosine phosphorylation of QKI in the developing myelin drastically declined, presumably leading to enhanced interactions between QKI and MBP mRNA, which was associated with the rapid accumulation of MBP mRNA and accelerated myelin production.	Tyrosine	33-41	myelin basic protein	Homo sapiens	172-175
12646656-6	2003	Furthermore, MBP-primed T cells isolated from NaPA-treated donor mice were also less efficient than MBP-primed T cells isolated from normal donor mice in inducing iNOS in microglial cells and transferring EAE to recipient mice.	Acecainide	46-50	myelin basic protein	Homo sapiens	13-16
12604313-3	2003	Also encephalitogenic myelin basic protein (MBP) is transferred with great efficiency onto HLA-DR molecules when H-bond donor molecules such as parachlorphenol (pCP) are present.	parachlorphenol	144-159	myelin basic protein	Homo sapiens	22-42
12620656-6	2003	Most MBP peptide-specific TCLs secreted considerable amounts of IFN-gamma and low amounts of IL-4 and IL-6, whereas anti rhMOG(Igd) peptide-specific TCLs secreted preferentially IL-4 and IL-6.	tcls	26-30	myelin basic protein	Homo sapiens	5-8
12421832-12	2003	The large number of disulfide bonds of the PAPP-A.pro-MBP complex imposes many restraints on polypeptide folding, and knowledge of the disulfide pattern of PAPP-A will facilitate structural studies based on recombinant expression of individual, putative PAPP-A domains.	Disulfides	20-29	myelin basic protein	Homo sapiens	54-57
12629084-8	2003	Furthermore, women on MBP experienced a 33% increase in urinary calcium excretion, whereas SP did not have such an effect.	Calcium	64-71	myelin basic protein	Homo sapiens	22-25
12576052-3	2003	The method is based on the knowledge that protein kinase C (PKC) adds three phosphates to each molecule of its preferred substrate, myelin basic protein (MBP).	Phosphates	76-86	myelin basic protein	Homo sapiens	132-152
12576052-3	2003	The method is based on the knowledge that protein kinase C (PKC) adds three phosphates to each molecule of its preferred substrate, myelin basic protein (MBP).	Phosphates	76-86	myelin basic protein	Homo sapiens	154-157
12551973-4	2003	(ii) A purified chimeric protein consisting of maltose binding protein (MBP) fused to a domain of EF-1delta containing Ser-133 (MBP-EFWt) is specifically phosphorylated in in vitro kinase assays by purified recombinant UL13 fused to glutathione S-transferase (GST) expressed in the baculovirus system.	Serine	119-122	myelin basic protein	Homo sapiens	72-75
12551973-4	2003	(ii) A purified chimeric protein consisting of maltose binding protein (MBP) fused to a domain of EF-1delta containing Ser-133 (MBP-EFWt) is specifically phosphorylated in in vitro kinase assays by purified recombinant UL13 fused to glutathione S-transferase (GST) expressed in the baculovirus system.	Serine	119-122	myelin basic protein	Homo sapiens	128-131
12604313-3	2003	Also encephalitogenic myelin basic protein (MBP) is transferred with great efficiency onto HLA-DR molecules when H-bond donor molecules such as parachlorphenol (pCP) are present.	parachlorphenol	144-159	myelin basic protein	Homo sapiens	44-47
12604313-3	2003	Also encephalitogenic myelin basic protein (MBP) is transferred with great efficiency onto HLA-DR molecules when H-bond donor molecules such as parachlorphenol (pCP) are present.	pcp	161-164	myelin basic protein	Homo sapiens	22-42
12604313-3	2003	Also encephalitogenic myelin basic protein (MBP) is transferred with great efficiency onto HLA-DR molecules when H-bond donor molecules such as parachlorphenol (pCP) are present.	pcp	161-164	myelin basic protein	Homo sapiens	44-47
12488049-3	2002	We constructed a series of maltose binding protein (MBP) fusion proteins representing overlapping fragments of the gp41 molecule and we studied their capacity to bind to cholesteryl beads.	cholesteryl	170-181	myelin basic protein	Homo sapiens	27-50
12421832-6	2003	To establish the connectivities of cysteine residues of the PAPP-A.pro-MBP complex, biochemical analyses of peptides derived from purified protein were performed.	Cysteine	35-43	myelin basic protein	Homo sapiens	71-74
12421832-9	2003	Within the 2:2 complex, PAPP-A is dimerized by a single disulfide bond; pro-MBP is dimerized by two disulfides, and each PAPP-A subunit is connected to a pro-MBP subunit by two disulfide bonds.	Disulfides	100-110	myelin basic protein	Homo sapiens	76-79
12421832-9	2003	Within the 2:2 complex, PAPP-A is dimerized by a single disulfide bond; pro-MBP is dimerized by two disulfides, and each PAPP-A subunit is connected to a pro-MBP subunit by two disulfide bonds.	Disulfides	100-109	myelin basic protein	Homo sapiens	76-79
12488049-3	2002	We constructed a series of maltose binding protein (MBP) fusion proteins representing overlapping fragments of the gp41 molecule and we studied their capacity to bind to cholesteryl beads.	cholesteryl	170-181	myelin basic protein	Homo sapiens	52-55
12381730-4	2002	To localize the ATP-binding site within the COOH terminus of Kir1.1, we produced and purified maltose-binding protein (MBP) fusion proteins containing truncated and/or mutated Kir1.1 COOH termini and examined the binding of TNP-ATP and competition by PIP(2).	Adenosine Triphosphate	16-19	myelin basic protein	Homo sapiens	94-117
12381730-4	2002	To localize the ATP-binding site within the COOH terminus of Kir1.1, we produced and purified maltose-binding protein (MBP) fusion proteins containing truncated and/or mutated Kir1.1 COOH termini and examined the binding of TNP-ATP and competition by PIP(2).	Adenosine Triphosphate	16-19	myelin basic protein	Homo sapiens	119-122
12488049-6	2002	We demonstrated that the sequence LWYIK synthesized fused to the MBP was able to bind to cholesteryl groups.	cholesteryl	89-100	myelin basic protein	Homo sapiens	65-68
12488049-7	2002	A synthetic peptide containing the sequence LWYIK was found to inhibit the interaction between cholesteryl beads and MBP44, an MBP fusion HIV-1 envelope protein that contains the putative cholesterol binding domain.	cholesteryl	95-106	myelin basic protein	Homo sapiens	117-120
12488049-7	2002	A synthetic peptide containing the sequence LWYIK was found to inhibit the interaction between cholesteryl beads and MBP44, an MBP fusion HIV-1 envelope protein that contains the putative cholesterol binding domain.	Cholesterol	188-199	myelin basic protein	Homo sapiens	117-120
12406676-6	2002	MBP-tTF was purified by amylose affinity chromatography.	Amylose	24-31	myelin basic protein	Homo sapiens	0-3
12427485-7	2002	Using RT-PCR and flow cytometry, it was found that EGCG upregulated the gene and protein expression of two eosinophil-specific granule proteins, the major basic protein (MBP) and eosinophil peroxidase (EPO), in EoL-1 cells.	epigallocatechin gallate	51-55	myelin basic protein	Homo sapiens	149-168
12427485-7	2002	Using RT-PCR and flow cytometry, it was found that EGCG upregulated the gene and protein expression of two eosinophil-specific granule proteins, the major basic protein (MBP) and eosinophil peroxidase (EPO), in EoL-1 cells.	epigallocatechin gallate	51-55	myelin basic protein	Homo sapiens	170-173
12202480-7	2002	In vitro mutational analyses of the MBP-P2 promoter showed that both the GATA-1/PU.1 synergy, and repressor activity of C/EBPepsilon(27) are mediated via protein-protein interactions through the C/EBP and/or GATA-binding sites but not the PU.1 sites.	gata	73-77	myelin basic protein	Homo sapiens	36-39
12163197-3	2002	The results indicate that while long-term treatment with GA results in a 2.9-fold decrease in the estimated precursor frequency of GA-reactive T-cells, the sustained response to GA remains Th2-biased and in part cross-reactive with MBP and MBP (83-99) as measured by proliferation and cytokine release assays.	Glatiramer Acetate	57-59	myelin basic protein	Homo sapiens	232-235
12372563-6	2002	Of these compounds, only CoQ(10) or NAC was able to restore the numbers of mature myelin basic protein-positive cells and the ability of the oligodendrocytes to form membrane sheets.	coq	25-28	myelin basic protein	Homo sapiens	82-102
12372563-6	2002	Of these compounds, only CoQ(10) or NAC was able to restore the numbers of mature myelin basic protein-positive cells and the ability of the oligodendrocytes to form membrane sheets.	Acetylcysteine	36-39	myelin basic protein	Homo sapiens	82-102
12163197-3	2002	The results indicate that while long-term treatment with GA results in a 2.9-fold decrease in the estimated precursor frequency of GA-reactive T-cells, the sustained response to GA remains Th2-biased and in part cross-reactive with MBP and MBP (83-99) as measured by proliferation and cytokine release assays.	Glatiramer Acetate	57-59	myelin basic protein	Homo sapiens	240-243
12230322-4	2002	Apoptosis was induced in autologous thymocytes and myelin basic protein (MBP)-specific T-cells by methylprednisolone (MP) or by irradiation.	Methylprednisolone	98-116	myelin basic protein	Homo sapiens	51-71
12230322-4	2002	Apoptosis was induced in autologous thymocytes and myelin basic protein (MBP)-specific T-cells by methylprednisolone (MP) or by irradiation.	Methylprednisolone	98-116	myelin basic protein	Homo sapiens	73-76
12230322-4	2002	Apoptosis was induced in autologous thymocytes and myelin basic protein (MBP)-specific T-cells by methylprednisolone (MP) or by irradiation.	Methylprednisolone	118-120	myelin basic protein	Homo sapiens	51-71
12230322-4	2002	Apoptosis was induced in autologous thymocytes and myelin basic protein (MBP)-specific T-cells by methylprednisolone (MP) or by irradiation.	Methylprednisolone	118-120	myelin basic protein	Homo sapiens	73-76
12665309-1	2002	The triplet state of 4-methoxybenzophenone (4-MBP) has been investigated by laser flash photolysis and emission techniques in several solvents.	4-methoxybenzophenone	21-42	myelin basic protein	Homo sapiens	46-49
12665309-2	2002	In non-polar cyclohexane, 4-MBP triplet has an (n,pi*) configuration with the typical triplet-triplet absorption spectrum of benzophenone (lambda(max) ca.	Cyclohexane	13-24	myelin basic protein	Homo sapiens	28-31
12665309-2	2002	In non-polar cyclohexane, 4-MBP triplet has an (n,pi*) configuration with the typical triplet-triplet absorption spectrum of benzophenone (lambda(max) ca.	benzophenone	125-137	myelin basic protein	Homo sapiens	28-31
12665309-6	2002	Further, transient absorption spectra due to T1 (n,pi*) and T2 (pi,pi*) being simultaneously populated are observed upon laser excitation of 4-MBP in polar solvents such as acetonitrile or methanol.	acetonitrile	173-185	myelin basic protein	Homo sapiens	143-146
12665309-6	2002	Further, transient absorption spectra due to T1 (n,pi*) and T2 (pi,pi*) being simultaneously populated are observed upon laser excitation of 4-MBP in polar solvents such as acetonitrile or methanol.	Methanol	189-197	myelin basic protein	Homo sapiens	143-146
12665309-12	2002	In polar organic solvents such as acetonitrile, the transient absorption spectrum and the quenching rate constant of hydrogen abstraction for triplet 4-ABP are practically the same as those obtained for 4-MBP in aqueous solutions.	acetonitrile	34-46	myelin basic protein	Homo sapiens	205-208
12665309-12	2002	In polar organic solvents such as acetonitrile, the transient absorption spectrum and the quenching rate constant of hydrogen abstraction for triplet 4-ABP are practically the same as those obtained for 4-MBP in aqueous solutions.	Hydrogen	117-125	myelin basic protein	Homo sapiens	205-208
12135568-1	2002	The degree of post-translational enzymatic deimination (conversion of arginyl to citrullinyl residues) of myelin basic protein (MBP) is correlated with the severity of the human autoimmune disease multiple sclerosis (MS).	arginyl	70-77	myelin basic protein	Homo sapiens	106-126
12166506-2	2002	In order to define an activity profile in patients with multiple sclerosis (MS), T-cell subpopulations and proliferative responses to myelin basic protein (MBP) associated with anti-MBP antibodies, nitrotyrosine levels in serum and cerebrospinal fluid (CSF), and serum CD40L (sCD154) were simultaneously assessed in 29 consecutive and untreated MS patients.	3-nitrotyrosine	198-211	myelin basic protein	Homo sapiens	134-154
12166506-2	2002	In order to define an activity profile in patients with multiple sclerosis (MS), T-cell subpopulations and proliferative responses to myelin basic protein (MBP) associated with anti-MBP antibodies, nitrotyrosine levels in serum and cerebrospinal fluid (CSF), and serum CD40L (sCD154) were simultaneously assessed in 29 consecutive and untreated MS patients.	3-nitrotyrosine	198-211	myelin basic protein	Homo sapiens	156-159
12166506-4	2002	In addition, in vitro-specific T-cell proliferative responses against MBP (SP/A, RR/A, SP/I: p < 0.001 versus controls) in association with augmented sCD154 serum levels (SP/A, RR/A, versus controls p < 0.001) and a significant increase of both CSF and serum levels of anti-MBP antibodies and nitrotyrosine levels (p < 0.001) were also found.	3-nitrotyrosine	299-312	myelin basic protein	Homo sapiens	70-73
12135568-1	2002	The degree of post-translational enzymatic deimination (conversion of arginyl to citrullinyl residues) of myelin basic protein (MBP) is correlated with the severity of the human autoimmune disease multiple sclerosis (MS).	arginyl	70-77	myelin basic protein	Homo sapiens	128-131
12135568-1	2002	The degree of post-translational enzymatic deimination (conversion of arginyl to citrullinyl residues) of myelin basic protein (MBP) is correlated with the severity of the human autoimmune disease multiple sclerosis (MS).	citrullinyl	81-92	myelin basic protein	Homo sapiens	106-126
12135568-1	2002	The degree of post-translational enzymatic deimination (conversion of arginyl to citrullinyl residues) of myelin basic protein (MBP) is correlated with the severity of the human autoimmune disease multiple sclerosis (MS).	citrullinyl	81-92	myelin basic protein	Homo sapiens	128-131
12135568-4	2002	The residues were chosen to correspond to the 6 Arg residues in human MBP which are most commonly deiminated in chronic MS.	Arginine	48-51	myelin basic protein	Homo sapiens	70-73
12070311-2	2002	In the present study, novel random four-amino acid copolymers, whose design was based on the nature of the anchor residues of the immunodominant epitope of myelin basic protein (MBP) 85-99 and of the binding pockets of MS-associated HLA-DR2 (DRB1*1501), have been synthesized by solid-phase chemistry.	amino acid copolymers	40-61	myelin basic protein	Homo sapiens	156-176
12496117-5	2002	The myelin basic protein induces a distortion on the Zn local environment due to a steric constraint but does not substitute the phosphate headgroups.	Zinc	53-55	myelin basic protein	Homo sapiens	4-24
12070311-2	2002	In the present study, novel random four-amino acid copolymers, whose design was based on the nature of the anchor residues of the immunodominant epitope of myelin basic protein (MBP) 85-99 and of the binding pockets of MS-associated HLA-DR2 (DRB1*1501), have been synthesized by solid-phase chemistry.	amino acid copolymers	40-61	myelin basic protein	Homo sapiens	178-181
11971002-4	2002	Functional defects are caused by structural changes to the N-terminal collagenous and cysteine-rich domains of MBP, disrupting interactions with associated serine proteases.	Cysteine	86-94	myelin basic protein	Homo sapiens	111-114
12137242-3	2002	AIM: To investigate the effect of synthetic cationic polypeptides such as poly-L-arginine, which can mimic the effect of MBP, on airway epithelial cells.	polyarginine	74-89	myelin basic protein	Homo sapiens	121-124
11850428-5	2002	The crystal structures of MBP-A soaked with monosaccharides and disaccharides and also the structure of the MBP-A trimer cross-linked by a high mannose asparaginyl oligosaccharide reveal that monosaccharides or alpha1-6-linked mannose bind to MBP-A in one orientation, whereas alpha1-2- or alpha1-3-linked mannose binds in an orientation rotated 180 degrees around a local symmetry axis relating the 3- and 4-OH groups.	Disaccharides	64-77	myelin basic protein	Homo sapiens	26-29
11850428-5	2002	The crystal structures of MBP-A soaked with monosaccharides and disaccharides and also the structure of the MBP-A trimer cross-linked by a high mannose asparaginyl oligosaccharide reveal that monosaccharides or alpha1-6-linked mannose bind to MBP-A in one orientation, whereas alpha1-2- or alpha1-3-linked mannose binds in an orientation rotated 180 degrees around a local symmetry axis relating the 3- and 4-OH groups.	mannose asparaginyl oligosaccharide	144-179	myelin basic protein	Homo sapiens	108-111
11850428-5	2002	The crystal structures of MBP-A soaked with monosaccharides and disaccharides and also the structure of the MBP-A trimer cross-linked by a high mannose asparaginyl oligosaccharide reveal that monosaccharides or alpha1-6-linked mannose bind to MBP-A in one orientation, whereas alpha1-2- or alpha1-3-linked mannose binds in an orientation rotated 180 degrees around a local symmetry axis relating the 3- and 4-OH groups.	mannose asparaginyl oligosaccharide	144-179	myelin basic protein	Homo sapiens	108-111
11850428-5	2002	The crystal structures of MBP-A soaked with monosaccharides and disaccharides and also the structure of the MBP-A trimer cross-linked by a high mannose asparaginyl oligosaccharide reveal that monosaccharides or alpha1-6-linked mannose bind to MBP-A in one orientation, whereas alpha1-2- or alpha1-3-linked mannose binds in an orientation rotated 180 degrees around a local symmetry axis relating the 3- and 4-OH groups.	Monosaccharides	192-207	myelin basic protein	Homo sapiens	26-29
11850428-5	2002	The crystal structures of MBP-A soaked with monosaccharides and disaccharides and also the structure of the MBP-A trimer cross-linked by a high mannose asparaginyl oligosaccharide reveal that monosaccharides or alpha1-6-linked mannose bind to MBP-A in one orientation, whereas alpha1-2- or alpha1-3-linked mannose binds in an orientation rotated 180 degrees around a local symmetry axis relating the 3- and 4-OH groups.	Monosaccharides	192-207	myelin basic protein	Homo sapiens	108-111
11850428-5	2002	The crystal structures of MBP-A soaked with monosaccharides and disaccharides and also the structure of the MBP-A trimer cross-linked by a high mannose asparaginyl oligosaccharide reveal that monosaccharides or alpha1-6-linked mannose bind to MBP-A in one orientation, whereas alpha1-2- or alpha1-3-linked mannose binds in an orientation rotated 180 degrees around a local symmetry axis relating the 3- and 4-OH groups.	Monosaccharides	192-207	myelin basic protein	Homo sapiens	108-111
11850428-5	2002	The crystal structures of MBP-A soaked with monosaccharides and disaccharides and also the structure of the MBP-A trimer cross-linked by a high mannose asparaginyl oligosaccharide reveal that monosaccharides or alpha1-6-linked mannose bind to MBP-A in one orientation, whereas alpha1-2- or alpha1-3-linked mannose binds in an orientation rotated 180 degrees around a local symmetry axis relating the 3- and 4-OH groups.	Mannose	144-151	myelin basic protein	Homo sapiens	108-111
11850428-5	2002	The crystal structures of MBP-A soaked with monosaccharides and disaccharides and also the structure of the MBP-A trimer cross-linked by a high mannose asparaginyl oligosaccharide reveal that monosaccharides or alpha1-6-linked mannose bind to MBP-A in one orientation, whereas alpha1-2- or alpha1-3-linked mannose binds in an orientation rotated 180 degrees around a local symmetry axis relating the 3- and 4-OH groups.	Mannose	144-151	myelin basic protein	Homo sapiens	108-111
11850428-7	2002	The mutation of MBP-A His(189) to its MBP-C equivalent, valine, causes Man alpha 1-3Man to bind in a mixture of orientations.	Histidine	22-25	myelin basic protein	Homo sapiens	16-19
11850428-7	2002	The mutation of MBP-A His(189) to its MBP-C equivalent, valine, causes Man alpha 1-3Man to bind in a mixture of orientations.	Valine	56-62	myelin basic protein	Homo sapiens	16-19
11850428-5	2002	The crystal structures of MBP-A soaked with monosaccharides and disaccharides and also the structure of the MBP-A trimer cross-linked by a high mannose asparaginyl oligosaccharide reveal that monosaccharides or alpha1-6-linked mannose bind to MBP-A in one orientation, whereas alpha1-2- or alpha1-3-linked mannose binds in an orientation rotated 180 degrees around a local symmetry axis relating the 3- and 4-OH groups.	Monosaccharides	44-59	myelin basic protein	Homo sapiens	26-29
11983216-6	2002	The success of the assay is dependent on the use of heparin, an anionic molecule, which neutralizes the positive charge on the highly cationic MBP.	Heparin	52-59	myelin basic protein	Homo sapiens	143-146
11971121-4	2002	Glatiramer acetate, a synthetic molecule, inhibits the activation of myelin basic protein-reactive T cells and induces a T-cell repertoire characterized by anti-inflammatory effects.	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	69-89
12034141-0	2002	Cyclic AMP inducibility of the myelin basic protein gene promoter requires the NF1 site.	Cyclic AMP	0-10	myelin basic protein	Homo sapiens	31-51
12034141-2	2002	One of the signals leading to the expression of myelin components, such as the myelin basic protein (MBP) gene is cyclic AMP (cAMP).	Cyclic AMP	114-124	myelin basic protein	Homo sapiens	79-99
12034141-2	2002	One of the signals leading to the expression of myelin components, such as the myelin basic protein (MBP) gene is cyclic AMP (cAMP).	Cyclic AMP	114-124	myelin basic protein	Homo sapiens	101-104
12034141-2	2002	One of the signals leading to the expression of myelin components, such as the myelin basic protein (MBP) gene is cyclic AMP (cAMP).	Cyclic AMP	126-130	myelin basic protein	Homo sapiens	79-99
12034141-2	2002	One of the signals leading to the expression of myelin components, such as the myelin basic protein (MBP) gene is cyclic AMP (cAMP).	Cyclic AMP	126-130	myelin basic protein	Homo sapiens	101-104
12034141-3	2002	Previous work using a cell line in which the endogenous MBP gene can be induced by increased cAMP levels (D6P2T) showed that the region of the MBP gene that was required for induction of the gene by cAMP lay between -248 and -105 in the 5" flanking region.	Cyclic AMP	93-97	myelin basic protein	Homo sapiens	56-59
12034141-3	2002	Previous work using a cell line in which the endogenous MBP gene can be induced by increased cAMP levels (D6P2T) showed that the region of the MBP gene that was required for induction of the gene by cAMP lay between -248 and -105 in the 5" flanking region.	Cyclic AMP	93-97	myelin basic protein	Homo sapiens	143-146
12034141-3	2002	Previous work using a cell line in which the endogenous MBP gene can be induced by increased cAMP levels (D6P2T) showed that the region of the MBP gene that was required for induction of the gene by cAMP lay between -248 and -105 in the 5" flanking region.	Cyclic AMP	199-203	myelin basic protein	Homo sapiens	56-59
12034141-3	2002	Previous work using a cell line in which the endogenous MBP gene can be induced by increased cAMP levels (D6P2T) showed that the region of the MBP gene that was required for induction of the gene by cAMP lay between -248 and -105 in the 5" flanking region.	Cyclic AMP	199-203	myelin basic protein	Homo sapiens	143-146
12034141-5	2002	In order to determine if the NF1 site itself was specifically responsible for the cAMP responsiveness of the MBP promoter, stably transfected cells carrying MBP promoter deletion constructs were used.	Cyclic AMP	82-86	myelin basic protein	Homo sapiens	109-112
12034141-9	2002	These results demonstrate that the NF1 site is indispensable for cAMP responsiveness of the MBP promoter and, together with other DNA elements, plays a role in controlling MBP gene expression.	Cyclic AMP	65-69	myelin basic protein	Homo sapiens	92-95
12034141-9	2002	These results demonstrate that the NF1 site is indispensable for cAMP responsiveness of the MBP promoter and, together with other DNA elements, plays a role in controlling MBP gene expression.	Cyclic AMP	65-69	myelin basic protein	Homo sapiens	172-175
12007981-3	2002	The phosphorylation of Ser31-containing peptides from type 1 human TH by activated, recombinant ERK2 was found to exhibit catalytic efficiencies (V(max)/K(m)) up to 4-fold higher than that of a synthetic myelin basic protein (MBP)-based peptide.	Peptides	40-48	myelin basic protein	Homo sapiens	204-224
12007981-3	2002	The phosphorylation of Ser31-containing peptides from type 1 human TH by activated, recombinant ERK2 was found to exhibit catalytic efficiencies (V(max)/K(m)) up to 4-fold higher than that of a synthetic myelin basic protein (MBP)-based peptide.	Peptides	40-48	myelin basic protein	Homo sapiens	226-229
11997124-6	2002	The immunolabeling of two major proteins of myelin (myelin basic protein, proteolipid-DM20) and of 2",3"-cyclic nucleotide 3"-phosphodiesterase shows colocalization with probes partitioning preferentially in liquid-expanded lipid domains also containing ganglioside G(M1).	Gangliosides	254-265	myelin basic protein	Homo sapiens	52-72
11784132-9	2002	In addition, the analogue cyclo(87-99)[Arg(91), Ala(96)]MBP(87-99) induced proliferation of human peripheral blood T-cells.	emodepside	26-31	myelin basic protein	Homo sapiens	56-59
11939588-12	2002	Ceramide monohexoside (CMH) levels correlated highly with the expression of mRNA for 4 myelin proteins: CGT, MBP, CNP, and PLP.	ceramide monohexoside	0-21	myelin basic protein	Homo sapiens	109-112
11939588-12	2002	Ceramide monohexoside (CMH) levels correlated highly with the expression of mRNA for 4 myelin proteins: CGT, MBP, CNP, and PLP.	ceramide monohexoside	23-26	myelin basic protein	Homo sapiens	109-112
11784132-9	2002	In addition, the analogue cyclo(87-99)[Arg(91), Ala(96)]MBP(87-99) induced proliferation of human peripheral blood T-cells.	Arginine	39-42	myelin basic protein	Homo sapiens	56-59
11784132-9	2002	In addition, the analogue cyclo(87-99)[Arg(91), Ala(96)]MBP(87-99) induced proliferation of human peripheral blood T-cells.	Alanine	48-51	myelin basic protein	Homo sapiens	56-59
11886166-6	2002	The protocol exploits the high binding affinity of MBP for amylose resin or vIL-10 for heparin and the ability of Triton-X114 to dissociate endotoxins from proteins.	Amylose	59-66	myelin basic protein	Homo sapiens	51-54
11886166-2	2002	The MBP-vIL-10 fusion protein was expressed in Escherichia coli and purified from cell lysates using amylose resin chromatography.	Amylose	101-108	myelin basic protein	Homo sapiens	4-7
11886166-6	2002	The protocol exploits the high binding affinity of MBP for amylose resin or vIL-10 for heparin and the ability of Triton-X114 to dissociate endotoxins from proteins.	vil-10	76-82	myelin basic protein	Homo sapiens	51-54
11886166-6	2002	The protocol exploits the high binding affinity of MBP for amylose resin or vIL-10 for heparin and the ability of Triton-X114 to dissociate endotoxins from proteins.	Heparin	87-94	myelin basic protein	Homo sapiens	51-54
11795782-0	2002	Amperometric TNT biosensor based on the oriented immobilization of a nitroreductase maltose binding protein fusion.	Trinitrotoluene	13-16	myelin basic protein	Homo sapiens	84-107
11795782-1	2002	The preparation and characterization of an amperometric 2,4,6-trinitrotoluene (TNT) biosensor based on the surface immobilization of a maltose binding protein (MBP) nitroreductase (NR) fusion (MBP-NR) onto an electrode modified with an electropolymerized film of N-(3-pyrrol-1-ylpropyl)-4,4"-bipyridine (PPB) are described.	Trinitrotoluene	56-77	myelin basic protein	Homo sapiens	135-158
11795782-1	2002	The preparation and characterization of an amperometric 2,4,6-trinitrotoluene (TNT) biosensor based on the surface immobilization of a maltose binding protein (MBP) nitroreductase (NR) fusion (MBP-NR) onto an electrode modified with an electropolymerized film of N-(3-pyrrol-1-ylpropyl)-4,4"-bipyridine (PPB) are described.	Trinitrotoluene	56-77	myelin basic protein	Homo sapiens	160-163
11795782-1	2002	The preparation and characterization of an amperometric 2,4,6-trinitrotoluene (TNT) biosensor based on the surface immobilization of a maltose binding protein (MBP) nitroreductase (NR) fusion (MBP-NR) onto an electrode modified with an electropolymerized film of N-(3-pyrrol-1-ylpropyl)-4,4"-bipyridine (PPB) are described.	Trinitrotoluene	56-77	myelin basic protein	Homo sapiens	193-196
11795782-1	2002	The preparation and characterization of an amperometric 2,4,6-trinitrotoluene (TNT) biosensor based on the surface immobilization of a maltose binding protein (MBP) nitroreductase (NR) fusion (MBP-NR) onto an electrode modified with an electropolymerized film of N-(3-pyrrol-1-ylpropyl)-4,4"-bipyridine (PPB) are described.	Trinitrotoluene	79-82	myelin basic protein	Homo sapiens	135-158
11795782-1	2002	The preparation and characterization of an amperometric 2,4,6-trinitrotoluene (TNT) biosensor based on the surface immobilization of a maltose binding protein (MBP) nitroreductase (NR) fusion (MBP-NR) onto an electrode modified with an electropolymerized film of N-(3-pyrrol-1-ylpropyl)-4,4"-bipyridine (PPB) are described.	Trinitrotoluene	79-82	myelin basic protein	Homo sapiens	160-163
11795782-1	2002	The preparation and characterization of an amperometric 2,4,6-trinitrotoluene (TNT) biosensor based on the surface immobilization of a maltose binding protein (MBP) nitroreductase (NR) fusion (MBP-NR) onto an electrode modified with an electropolymerized film of N-(3-pyrrol-1-ylpropyl)-4,4"-bipyridine (PPB) are described.	Trinitrotoluene	79-82	myelin basic protein	Homo sapiens	193-196
11795782-1	2002	The preparation and characterization of an amperometric 2,4,6-trinitrotoluene (TNT) biosensor based on the surface immobilization of a maltose binding protein (MBP) nitroreductase (NR) fusion (MBP-NR) onto an electrode modified with an electropolymerized film of N-(3-pyrrol-1-ylpropyl)-4,4"-bipyridine (PPB) are described.	n-(3-pyrrol-1-ylpropyl)-4,4'-bipyridine	263-302	myelin basic protein	Homo sapiens	160-163
11795782-1	2002	The preparation and characterization of an amperometric 2,4,6-trinitrotoluene (TNT) biosensor based on the surface immobilization of a maltose binding protein (MBP) nitroreductase (NR) fusion (MBP-NR) onto an electrode modified with an electropolymerized film of N-(3-pyrrol-1-ylpropyl)-4,4"-bipyridine (PPB) are described.	PPB	304-307	myelin basic protein	Homo sapiens	160-163
11795782-5	2002	The apparent Michaelis-Menten constants (KM) for MBP-NR in solution and on the surface, using TNT as substrate, were determined to be 27 and 95 microM, respectively.	Trinitrotoluene	94-97	myelin basic protein	Homo sapiens	49-52
11795782-6	2002	The corresponding value for "wild-type" NR in solution containing TNT was 78 microM, which is very close to the value obtained for MBP-NR on the surface.	Trinitrotoluene	66-69	myelin basic protein	Homo sapiens	131-134
11747548-3	2002	RESULTS: For cells irradiated with high LET nitrogen ions, there was an increase in the fast half-time from approximately 5 min for fragments < 400 kbp to 10 min when all fragments < 5.7 Mbp were measured.	Nitrogen	44-52	myelin basic protein	Homo sapiens	193-196
12142036-0	2002	Retinoic acid promotes the development of Th2-like human myelin basic protein-reactive T cells.	Tretinoin	0-13	myelin basic protein	Homo sapiens	57-77
11841829-1	2002	Binary lipid monolayers consisting of equimolar proportions of a phosphoinositide and a nickel-chelating lipid formed helical tubular vesicular structures, which appeared to be induced and/or stabilized by myelin basic protein (MBP).	Phosphatidylinositols	65-81	myelin basic protein	Homo sapiens	206-226
11841829-1	2002	Binary lipid monolayers consisting of equimolar proportions of a phosphoinositide and a nickel-chelating lipid formed helical tubular vesicular structures, which appeared to be induced and/or stabilized by myelin basic protein (MBP).	Phosphatidylinositols	65-81	myelin basic protein	Homo sapiens	228-231
11841829-1	2002	Binary lipid monolayers consisting of equimolar proportions of a phosphoinositide and a nickel-chelating lipid formed helical tubular vesicular structures, which appeared to be induced and/or stabilized by myelin basic protein (MBP).	Nickel	88-94	myelin basic protein	Homo sapiens	206-226
11841829-1	2002	Binary lipid monolayers consisting of equimolar proportions of a phosphoinositide and a nickel-chelating lipid formed helical tubular vesicular structures, which appeared to be induced and/or stabilized by myelin basic protein (MBP).	Nickel	88-94	myelin basic protein	Homo sapiens	228-231
11771127-2	2001	Purine and pyrimidine nucleotide residues are unevenly distributed along both chromosomes, displaying maxima and minima (Y waves phi) with a period of about 3 Mbp.	purine	0-6	myelin basic protein	Homo sapiens	159-162
11473818-6	2002	Bismuth hematoxylin is selective for arginine residues and thus for histones and myelin basic protein in tissues fixed in strong acids (Bouin"s fluid or SUSA fluid).	bismuth hematoxylin	0-19	myelin basic protein	Homo sapiens	81-101
11595747-2	2001	The bacterial expression of the MBP/gp21 chimeras resulted in soluble trimers containing intramonomer disulfide bonds.	Disulfides	102-111	myelin basic protein	Homo sapiens	32-35
11595747-6	2001	In addition, thermal aggregation experiments indicated that the Thr(425)-Ser(436) sequence confers stability to the fusion peptide-containing MBP/gp21 chimeras.	Threonine	64-67	myelin basic protein	Homo sapiens	142-145
11595747-6	2001	In addition, thermal aggregation experiments indicated that the Thr(425)-Ser(436) sequence confers stability to the fusion peptide-containing MBP/gp21 chimeras.	Serine	73-76	myelin basic protein	Homo sapiens	142-145
11595747-8	2001	By contrast, single alanine substitutions in MBP/gp21 did not significantly alter chimera stability, indicating that multiple residues within the transmembrane domain proximal region and the fusion peptide and adjacent glycine-rich segment contribute to stability, thereby mitigating the potential effects of the substitutions.	Alanine	20-27	myelin basic protein	Homo sapiens	45-48
11746371-4	2001	In the present study the T cell response to MBP was longitudinally investigated in terms of frequency, epitope specificity, and cytokine production profile in four patients with relapsing-remitting MS enrolled in a gadolinium-enhanced MRI serial study.	Gadolinium	215-225	myelin basic protein	Homo sapiens	44-47
11720283-3	2001	Symmetrically dimethylated arginines (sDMA) have until now been confined to the myelin basic protein MBP and the Sm proteins D1 and D3.	Arginine	27-36	myelin basic protein	Homo sapiens	101-104
11720283-3	2001	Symmetrically dimethylated arginines (sDMA) have until now been confined to the myelin basic protein MBP and the Sm proteins D1 and D3.	symmetric dimethylarginine	38-42	myelin basic protein	Homo sapiens	101-104
11771127-2	2001	Purine and pyrimidine nucleotide residues are unevenly distributed along both chromosomes, displaying maxima and minima (Y waves phi) with a period of about 3 Mbp.	Pyrimidine Nucleotides	11-32	myelin basic protein	Homo sapiens	159-162
11509612-3	2001	The crystal structure of HLA-DR2 complexed with myelin basic protein(84-102) confirmed that Lys(91) is the major TCR contact site, whereas Phe(90) is a major anchor to MHC and binds the hydrophobic P4 pocket (2 ).	Lysine	92-95	myelin basic protein	Homo sapiens	48-68
11578692-9	2001	These results indicate that two MBP peptide sequences, including one (89-117) that contains a unique carbohydrate-binding region, share the biologic activities of MBP.	Carbohydrates	101-113	myelin basic protein	Homo sapiens	32-35
11578692-9	2001	These results indicate that two MBP peptide sequences, including one (89-117) that contains a unique carbohydrate-binding region, share the biologic activities of MBP.	Carbohydrates	101-113	myelin basic protein	Homo sapiens	163-166
11564800-6	2001	Initial analysis of the basis of the interaction between CD45 and MBP suggests MBP binds two different glycoforms of CD45 based on the differential competition with glucose.	Glucose	165-172	myelin basic protein	Homo sapiens	66-69
11564800-6	2001	Initial analysis of the basis of the interaction between CD45 and MBP suggests MBP binds two different glycoforms of CD45 based on the differential competition with glucose.	Glucose	165-172	myelin basic protein	Homo sapiens	79-82
11599000-0	2001	Effect of cyclic AMP on the expression of myelin basic protein species and myelin proteolipid protein in committed oligodendrocytes: differential involvement of the transcription factor CREB.	Cyclic AMP	10-20	myelin basic protein	Homo sapiens	42-62
11599000-3	2001	In contrast, at a later stage, when cells are already committed oligodendrocytes, CREB seems to play an important role as a mediator in the stimulation of myelin basic protein (MBP) expression by cyclic AMP (cAMP).	Cyclic AMP	196-206	myelin basic protein	Homo sapiens	155-175
11599000-3	2001	In contrast, at a later stage, when cells are already committed oligodendrocytes, CREB seems to play an important role as a mediator in the stimulation of myelin basic protein (MBP) expression by cyclic AMP (cAMP).	Cyclic AMP	196-206	myelin basic protein	Homo sapiens	177-180
11599000-3	2001	In contrast, at a later stage, when cells are already committed oligodendrocytes, CREB seems to play an important role as a mediator in the stimulation of myelin basic protein (MBP) expression by cyclic AMP (cAMP).	Cyclic AMP	208-212	myelin basic protein	Homo sapiens	155-175
11599000-3	2001	In contrast, at a later stage, when cells are already committed oligodendrocytes, CREB seems to play an important role as a mediator in the stimulation of myelin basic protein (MBP) expression by cyclic AMP (cAMP).	Cyclic AMP	208-212	myelin basic protein	Homo sapiens	177-180
11599000-4	2001	In this study, we have investigated whether cAMP and CREB play a role in regulating the expression of all or on the other hand particular MBP isoforms.	Cyclic AMP	44-48	myelin basic protein	Homo sapiens	138-141
11599000-5	2001	The results indicated that treatment of committed oligodendrocytes with the cAMP analogue db-cAMP results in a pattern of expression of MBP-related polypeptides that most closely resembles the pattern of MBPs observed in cerebra from adult animals.	Cyclic AMP	76-80	myelin basic protein	Homo sapiens	136-139
11599000-5	2001	The results indicated that treatment of committed oligodendrocytes with the cAMP analogue db-cAMP results in a pattern of expression of MBP-related polypeptides that most closely resembles the pattern of MBPs observed in cerebra from adult animals.	db-cAMP	90-97	myelin basic protein	Homo sapiens	136-139
11599000-6	2001	Experiments in which CREB expression was inhibited using a CREB antisense oligonucleotide, suggested that CREB is involved in the cAMP-dependent stimulation of all the MBP isoforms.	Oligonucleotides	74-89	myelin basic protein	Homo sapiens	168-171
11599000-6	2001	Experiments in which CREB expression was inhibited using a CREB antisense oligonucleotide, suggested that CREB is involved in the cAMP-dependent stimulation of all the MBP isoforms.	Cyclic AMP	130-134	myelin basic protein	Homo sapiens	168-171
11509612-3	2001	The crystal structure of HLA-DR2 complexed with myelin basic protein(84-102) confirmed that Lys(91) is the major TCR contact site, whereas Phe(90) is a major anchor to MHC and binds the hydrophobic P4 pocket (2 ).	Phenylalanine	139-142	myelin basic protein	Homo sapiens	48-68
11549352-9	2001	The recombinant histidine tagged MLK7 expressed and purified from insect cells exhibited serine/threonine kinase activity in vitro with myelin basic protein as substrate.	Histidine	16-25	myelin basic protein	Homo sapiens	136-156
11413150-2	2001	A hemagglutinin peptide-tagged PRMT5 complex purified from human HeLa cells catalyzes the S-adenosyl-l-[methyl-(3)H]methionine-dependent in vitro methylation of myelin basic protein.	Sulfur	90-92	myelin basic protein	Homo sapiens	161-181
11413150-2	2001	A hemagglutinin peptide-tagged PRMT5 complex purified from human HeLa cells catalyzes the S-adenosyl-l-[methyl-(3)H]methionine-dependent in vitro methylation of myelin basic protein.	adenosyl-l-[methyl-(3)h]methionine	92-126	myelin basic protein	Homo sapiens	161-181
11413150-9	2001	PRMT5 is the first example of a catalytic chain for a type II protein arginine N-methyltransferase that can result in the formation of symmetric dimethylarginine residues as observed previously in myelin basic protein, Sm small nuclear ribonucleoproteins, and other polypeptides.	dimethylarginine	145-161	myelin basic protein	Homo sapiens	197-217
11399042-2	2001	The fused fragment of myelin basic protein contains a single consensus ERK/MAP kinase phosphorylation motif (PRTP, where the threonine is phosphorylated).	Threonine	125-134	myelin basic protein	Homo sapiens	22-42
11548979-0	2001	Glatiramer acetate induces a Th2-biased response and crossreactivity with myelin basic protein in patients with MS. Glatiromer acetate (GA) is an approved treatment for multiple sclerosis (MS).	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	74-94
11548979-0	2001	Glatiramer acetate induces a Th2-biased response and crossreactivity with myelin basic protein in patients with MS. Glatiromer acetate (GA) is an approved treatment for multiple sclerosis (MS).	glatiromer acetate	116-134	myelin basic protein	Homo sapiens	74-94
11548979-0	2001	Glatiramer acetate induces a Th2-biased response and crossreactivity with myelin basic protein in patients with MS. Glatiromer acetate (GA) is an approved treatment for multiple sclerosis (MS).	Gallium	136-138	myelin basic protein	Homo sapiens	74-94
11548979-9	2001	Some GA-specific TCL, (approximately 25%) generated during treatment secreted predominantly IL-5 in response to MBP and the immunodominant MBP peptide 83-99, indicating that these crossreactive antigens can act as partial agonists for GA-reactive TCL.	Gallium	5-7	myelin basic protein	Homo sapiens	112-115
11548979-9	2001	Some GA-specific TCL, (approximately 25%) generated during treatment secreted predominantly IL-5 in response to MBP and the immunodominant MBP peptide 83-99, indicating that these crossreactive antigens can act as partial agonists for GA-reactive TCL.	Gallium	5-7	myelin basic protein	Homo sapiens	139-142
11548979-9	2001	Some GA-specific TCL, (approximately 25%) generated during treatment secreted predominantly IL-5 in response to MBP and the immunodominant MBP peptide 83-99, indicating that these crossreactive antigens can act as partial agonists for GA-reactive TCL.	Triclosan	17-20	myelin basic protein	Homo sapiens	112-115
11548979-9	2001	Some GA-specific TCL, (approximately 25%) generated during treatment secreted predominantly IL-5 in response to MBP and the immunodominant MBP peptide 83-99, indicating that these crossreactive antigens can act as partial agonists for GA-reactive TCL.	Triclosan	17-20	myelin basic protein	Homo sapiens	139-142
11337510-2	2001	Serum mannose-binding protein (MBP) initiates the lectin branch of the complement cascade by binding to sugars on the surfaces of microorganisms and activating two MBP-associated serine proteases (MASP-1 and MASP-2).	Mannose	6-13	myelin basic protein	Homo sapiens	31-34
11337510-2	2001	Serum mannose-binding protein (MBP) initiates the lectin branch of the complement cascade by binding to sugars on the surfaces of microorganisms and activating two MBP-associated serine proteases (MASP-1 and MASP-2).	Mannose	6-13	myelin basic protein	Homo sapiens	164-167
11337510-2	2001	Serum mannose-binding protein (MBP) initiates the lectin branch of the complement cascade by binding to sugars on the surfaces of microorganisms and activating two MBP-associated serine proteases (MASP-1 and MASP-2).	Sugars	104-110	myelin basic protein	Homo sapiens	31-34
11371450-8	2001	In addition, we obtain volumetric data for the transition of myelin basic protein from its initially unfolded state in water free of denaturants, to a folded, compact conformation within the water-controlled microenvironment of reverse micelles.	Water	119-124	myelin basic protein	Homo sapiens	61-81
11399072-1	2001	Solution NMR studies on the physiologically relevant ligand-free and maltotriose-bound states of maltodextrin-binding protein (MBP) are presented.	maltotriose	69-80	myelin basic protein	Homo sapiens	97-125
11399072-1	2001	Solution NMR studies on the physiologically relevant ligand-free and maltotriose-bound states of maltodextrin-binding protein (MBP) are presented.	maltotriose	69-80	myelin basic protein	Homo sapiens	127-130
11399072-2	2001	Together with existing data on MBP in complex with beta-cyclodextrin (non-physiological, inactive ligand), these new results provide valuable information on changes in local structure, dynamics and global fold that occur upon ligand binding to this two-domain protein.	betadex	51-68	myelin basic protein	Homo sapiens	31-34
11399072-6	2001	These results are in contrast to those obtained for the MBP/beta-cyclodextrin complex where the solution state is found to be approximately 10 degrees more closed than the crystalline state.	betadex	60-77	myelin basic protein	Homo sapiens	56-59
11371450-3	2001	We explore, by densimetry and ultrasound velocimetry, three basic proteins: cytochrome c, lysozyme, and myelin basic protein in reverse micelles made of sodium bis (2-ethylhexyl) sulfosuccinate, water, and isooctane and in aqueous solvents.	Dioctyl Sulfosuccinic Acid	153-193	myelin basic protein	Homo sapiens	104-124
11371450-8	2001	In addition, we obtain volumetric data for the transition of myelin basic protein from its initially unfolded state in water free of denaturants, to a folded, compact conformation within the water-controlled microenvironment of reverse micelles.	Water	191-196	myelin basic protein	Homo sapiens	61-81
11292596-6	2001	The dissociation constant of Man-BSA and MBP decreased dramatically with increasing density of mannose, but the Michaelis-Menten constant of hepatic uptake of Man-BSA was not so sensitive to the change in density.	Mannose	95-102	myelin basic protein	Homo sapiens	41-44
11398076-5	2001	Heparin and pertussis toxin and different extracellular Ca(2+) concentrations were used to modulate mast cell reactivation by MBP.	Heparin	0-7	myelin basic protein	Homo sapiens	126-129
11356257-0	2001	Ethanol exerts different effects on myelin basic protein and 2",3"-cyclic nucleotide 3"-phosphodiesterase expression in differentiating CG-4 oligodendrocytes.	Ethanol	0-7	myelin basic protein	Homo sapiens	36-56
11356257-2	2001	We investigated the potential teratogenic effects of ethanol (EtOH) on myelin formation by determining its effects on the developmentally regulated increased expression of myelin basic protein (MBP) and 2",3"-cyclic nucleotide 3"-phosphodiesterase (CNP) in differentiating CG-4 oligodendrocytes (OLGs).	Ethanol	53-60	myelin basic protein	Homo sapiens	172-192
11356257-2	2001	We investigated the potential teratogenic effects of ethanol (EtOH) on myelin formation by determining its effects on the developmentally regulated increased expression of myelin basic protein (MBP) and 2",3"-cyclic nucleotide 3"-phosphodiesterase (CNP) in differentiating CG-4 oligodendrocytes (OLGs).	Ethanol	53-60	myelin basic protein	Homo sapiens	194-197
11356257-2	2001	We investigated the potential teratogenic effects of ethanol (EtOH) on myelin formation by determining its effects on the developmentally regulated increased expression of myelin basic protein (MBP) and 2",3"-cyclic nucleotide 3"-phosphodiesterase (CNP) in differentiating CG-4 oligodendrocytes (OLGs).	Ethanol	62-66	myelin basic protein	Homo sapiens	172-192
11356257-2	2001	We investigated the potential teratogenic effects of ethanol (EtOH) on myelin formation by determining its effects on the developmentally regulated increased expression of myelin basic protein (MBP) and 2",3"-cyclic nucleotide 3"-phosphodiesterase (CNP) in differentiating CG-4 oligodendrocytes (OLGs).	Ethanol	62-66	myelin basic protein	Homo sapiens	194-197
11356257-4	2001	During the first 8 days of development, EtOH decreased the expression of the major structural 18.5 and 14 kDa MBP isoforms by at least 40% at 4 days of development.	Ethanol	40-44	myelin basic protein	Homo sapiens	110-113
11356257-5	2001	EtOH concentrations between 25 and 75 mM inhibited MBP expression in a dose-dependent manner.	Ethanol	0-4	myelin basic protein	Homo sapiens	51-54
11356257-6	2001	Adding or withdrawing EtOH on specific days of differentiation reversibly modulated the expression of MBP, and the degree of inhibition was directly related to the length of ethanol exposure.	Ethanol	22-26	myelin basic protein	Homo sapiens	102-105
11356257-6	2001	Adding or withdrawing EtOH on specific days of differentiation reversibly modulated the expression of MBP, and the degree of inhibition was directly related to the length of ethanol exposure.	Ethanol	174-181	myelin basic protein	Homo sapiens	102-105
11356257-8	2001	The ethanol effect was selective for MBP expression, as EtOH did not alter the developmentally-regulated increased expression of CNP isozymes or enzyme activity.	Ethanol	4-11	myelin basic protein	Homo sapiens	37-40
11374693-8	2001	The degree of infiltrating eosinophils by hematoxylin and eosin was correlated with eosinophil infiltration and degranulation by MBP immunostaining; however, no other correlations were found between eosinophil infiltration or degranulation by immunofluorescence and any of the histological parameters measured in the CC group.	Hematoxylin	42-53	myelin basic protein	Homo sapiens	129-132
11374693-8	2001	The degree of infiltrating eosinophils by hematoxylin and eosin was correlated with eosinophil infiltration and degranulation by MBP immunostaining; however, no other correlations were found between eosinophil infiltration or degranulation by immunofluorescence and any of the histological parameters measured in the CC group.	Eosine Yellowish-(YS)	27-32	myelin basic protein	Homo sapiens	129-132
11329185-8	2001	This glutamate effect is not due to toxicity, since the number of total cells was unchanged, while the number of mature myelin basic protein positive (MBP+) cells increased.	Glutamic Acid	5-14	myelin basic protein	Homo sapiens	120-140
11430759-0	2001	Domain orientation in beta-cyclodextrin-loaded maltose binding protein: diffusion anisotropy measurements confirm the results of a dipolar coupling study.	betadex	22-39	myelin basic protein	Homo sapiens	47-70
11430759-1	2001	Maltose binding protein (MBP) is a 370-residue two-domain molecule involved in bacterial chemotaxis and sugar uptake.	Sugars	104-109	myelin basic protein	Homo sapiens	0-23
11430759-1	2001	Maltose binding protein (MBP) is a 370-residue two-domain molecule involved in bacterial chemotaxis and sugar uptake.	Sugars	104-109	myelin basic protein	Homo sapiens	25-28
11430759-2	2001	Rotational diffusion tensors were calculated for a complex between MBP and beta-cyclodextrin using backbone 15N T1 and T1rho relaxation times and steady state 1H-15N NOE values.	betadex	75-92	myelin basic protein	Homo sapiens	67-70
11430759-2	2001	Rotational diffusion tensors were calculated for a complex between MBP and beta-cyclodextrin using backbone 15N T1 and T1rho relaxation times and steady state 1H-15N NOE values.	Hydrogen	159-161	myelin basic protein	Homo sapiens	67-70
11152681-5	2001	Myelin basic protein methylated by PRMT5 contained monomethylated and dimethylated arginine residues.	Arginine	83-91	myelin basic protein	Homo sapiens	0-20
11388472-10	2001	As compared with the placebo group, urinary cross-linked N-teleopeptides of type-I collagen/creatinine and deoxypyridinoline/creatinine were significantly decreased in the MBP group (p < 0.05), while no significant differences between the two groups were observed in serum osteocalcin and bone-specific alkaline phosphatase concentrations.	Nitrogen	57-58	myelin basic protein	Homo sapiens	172-175
11388472-10	2001	As compared with the placebo group, urinary cross-linked N-teleopeptides of type-I collagen/creatinine and deoxypyridinoline/creatinine were significantly decreased in the MBP group (p < 0.05), while no significant differences between the two groups were observed in serum osteocalcin and bone-specific alkaline phosphatase concentrations.	Creatinine	92-102	myelin basic protein	Homo sapiens	172-175
11388472-10	2001	As compared with the placebo group, urinary cross-linked N-teleopeptides of type-I collagen/creatinine and deoxypyridinoline/creatinine were significantly decreased in the MBP group (p < 0.05), while no significant differences between the two groups were observed in serum osteocalcin and bone-specific alkaline phosphatase concentrations.	deoxypyridinoline	107-124	myelin basic protein	Homo sapiens	172-175
11388472-10	2001	As compared with the placebo group, urinary cross-linked N-teleopeptides of type-I collagen/creatinine and deoxypyridinoline/creatinine were significantly decreased in the MBP group (p < 0.05), while no significant differences between the two groups were observed in serum osteocalcin and bone-specific alkaline phosphatase concentrations.	Creatinine	125-135	myelin basic protein	Homo sapiens	172-175
16233148-3	2001	We developed a large-scale preparation system for recombinant human GnT-I (hGnT-I) using the maltose binding protein (MBP) fusion system to facilitate the chemoenzymatic route for complex-type N-linked glycan synthesis.	n-linked glycan	193-208	myelin basic protein	Homo sapiens	93-116
11295122-1	2001	OBJECTIVE: To investigate the relationship between mannose-binding protein(MBP) gene codon 54 (GGC/GAC) polymorphism and the patterns of glomerular immune deposition in IgA nephropathy (IgAN) and explore its functional significance.	Mannose	51-58	myelin basic protein	Homo sapiens	75-78
11174183-8	2001	When M2 receptors are blocked by MBP, acetylcholine release is increased, resulting in hyperresponsiveness.	Acetylcholine	38-51	myelin basic protein	Homo sapiens	33-36
11174183-9	2001	Neutralization of MBP with polyanionic substances restores M2 receptor function and eliminates hyperresponsiveness.	polyanionic substances	27-49	myelin basic protein	Homo sapiens	18-21
11162395-3	2001	MBP-His(8)-ORF2 was purified to homogeneity by immobilized metal affinity chromatography based on the interaction of the polyhistidine-tag with metal ions.	Metals	59-64	myelin basic protein	Homo sapiens	0-3
11162395-3	2001	MBP-His(8)-ORF2 was purified to homogeneity by immobilized metal affinity chromatography based on the interaction of the polyhistidine-tag with metal ions.	polyhistidine	121-134	myelin basic protein	Homo sapiens	0-3
11162395-3	2001	MBP-His(8)-ORF2 was purified to homogeneity by immobilized metal affinity chromatography based on the interaction of the polyhistidine-tag with metal ions.	Metals	144-149	myelin basic protein	Homo sapiens	0-3
11168355-6	2001	Binding was also observed between MBP-LOR3ARF and a pyrimidine-motif triplex DNA, although at lower affinity than Pu-triplex DNA.	pyrimidine	52-62	myelin basic protein	Homo sapiens	34-37
11123948-3	2000	The McbB subunit was purified as a fusion with the maltose-binding protein (MBP), and metal analysis revealed that this protein binds 0.91+/-0.17 zinc atoms.	Metals	86-91	myelin basic protein	Homo sapiens	76-79
11123948-4	2000	Upon incubation of MBP-McbB with excess zinc, the stoichiometry increased to two atoms of zinc bound, but metal binding to the second site resulted in a decrease in the heterocyclization activity when MBP-McbB was reconstituted with the other components of the synthetase.	Metals	106-111	myelin basic protein	Homo sapiens	19-22
11123948-4	2000	Upon incubation of MBP-McbB with excess zinc, the stoichiometry increased to two atoms of zinc bound, but metal binding to the second site resulted in a decrease in the heterocyclization activity when MBP-McbB was reconstituted with the other components of the synthetase.	Metals	106-111	myelin basic protein	Homo sapiens	201-204
11123948-6	2000	However, if dithiothreitol was added to the PMPS reactions within a few minutes, enzymatic activity was retained and MBP-McbB could be reconstituted with zinc.	Dithiothreitol	12-26	myelin basic protein	Homo sapiens	117-120
11123948-6	2000	However, if dithiothreitol was added to the PMPS reactions within a few minutes, enzymatic activity was retained and MBP-McbB could be reconstituted with zinc.	pmps	44-48	myelin basic protein	Homo sapiens	117-120
11113226-9	2000	RESULTS: GA more strongly inhibited the proliferation of MBP, as compared with foreign antigen-specific TCC; in some MBP-specific TCC, the production of Th1-type cytokines was preferentially inhibited.	Glatiramer Acetate	9-11	myelin basic protein	Homo sapiens	57-60
11745393-0	2001	Cathepsin S and an asparagine-specific endoprotease dominate the proteolytic processing of human myelin basic protein in vitro.	Asparagine	19-29	myelin basic protein	Homo sapiens	97-117
11125001-7	2000	Unilateral carotid ligation in combination with hypoxia (6% O(2) for 1 hr) resulted in selective, subcortical white matter injury with a marked ipsilateral decrease in immature and myelin basic protein-expressing OLs that was also significantly attenuated by 6-nitro-7-sulfamoylbenzo(f)quinoxaline-2,3-dione (NBQX).	o(2)	60-64	myelin basic protein	Homo sapiens	181-201
11042548-4	2000	Purified MBP-EC20 was shown to accumulate more Cd(2+) per peptide than typical mammalian metallothioneins with a stoichiometry of 10 Cd(2+)/peptide.	Cadmium	47-49	myelin basic protein	Homo sapiens	9-12
11122251-4	2000	1H6.2 and 45.30 MoAbs stained MBP from human brain white matter tissue extracts, as well as bLF-MBP, in Western blot assays.	CHEMBL2347205	0-3	myelin basic protein	Homo sapiens	30-33
11122251-10	2000	These findings support hypotheses regarding the role of MEs expressed by non-neural cells in establishing self-tolerance and/or in triggering the immune response against MBP antigen.	2-(N-morpholino)ethanesulfonic acid	56-59	myelin basic protein	Homo sapiens	170-173
11061987-3	2000	In-gel kinase assays with myelin basic protein as substrate revealed that taxol treatment significantly (P </= 0.05) reduced the activity of a 55 kD kinase present in cytoskeletal extracts from CV-1 cells.	Paclitaxel	74-79	myelin basic protein	Homo sapiens	26-46
11071371-6	2000	The degradation of myelin basic protein (MBP) by cathepsin B, a lysosomal cysteine protease, was significantly inhibited by indomethacin.	Indomethacin	124-136	myelin basic protein	Homo sapiens	19-39
11071371-6	2000	The degradation of myelin basic protein (MBP) by cathepsin B, a lysosomal cysteine protease, was significantly inhibited by indomethacin.	Indomethacin	124-136	myelin basic protein	Homo sapiens	41-44
11101201-6	2000	Losartan induced a significant (p < 0.001) decrease in SBP, DBP, and MBP versus baseline values both at 6 months and at 12 months.	Losartan	0-8	myelin basic protein	Homo sapiens	72-75
11064438-4	2000	The purpose of this Phase I open label clinical study was to monitor CSF anti-MBP in patients with chronic progressive MS subsequent to IV administration of synthetic peptide (sp) MBP82-98 namely DEN(85)VVHFFKNIVTP(96)RT.	Peptides	167-174	myelin basic protein	Homo sapiens	78-81
11064438-4	2000	The purpose of this Phase I open label clinical study was to monitor CSF anti-MBP in patients with chronic progressive MS subsequent to IV administration of synthetic peptide (sp) MBP82-98 namely DEN(85)VVHFFKNIVTP(96)RT.	sp	176-178	myelin basic protein	Homo sapiens	78-81
11064438-4	2000	The purpose of this Phase I open label clinical study was to monitor CSF anti-MBP in patients with chronic progressive MS subsequent to IV administration of synthetic peptide (sp) MBP82-98 namely DEN(85)VVHFFKNIVTP(96)RT.	Diethylnitrosamine	196-199	myelin basic protein	Homo sapiens	78-81
10971475-6	2000	The MBP-rHev b 1 fusion protein was examined by RAST with the CAP method, histamine release test and immunoblots with human sera from spina bifida patients as well as from health care workers with latex allergy and monoclonal antibodies.	Histamine	74-83	myelin basic protein	Homo sapiens	4-7
10971475-7	2000	RESULTS: Histamine release test and immunoblots revealed the high allergenicity of the MBP-rHev b 1 construct.	Histamine	9-18	myelin basic protein	Homo sapiens	87-90
11094853-9	2000	INTERPRETATION & CONCLUSIONS: The present study suggested that MBP and VDR genes influence the cell mediated immune response in pulmonary TB patients.	Adenosine Monophosphate	16-19	myelin basic protein	Homo sapiens	67-70
10965044-5	2000	The sc DR51 molecule showed high affinity to the self-peptide derived from myelin basic protein, 87-98 with Phe as the P1 residue (F90F).	Phenylalanine	108-111	myelin basic protein	Homo sapiens	75-95
11045608-6	2000	Carbohydrate binding has been structurally characterized in several complexes between MBP and carbohydrate; all indicate that the major interaction between carbohydrate and collectin is the binding of two adjacent carbohydrate hydroxyl group to a collectin calcium ion.	Carbohydrates	0-12	myelin basic protein	Homo sapiens	86-89
11045608-6	2000	Carbohydrate binding has been structurally characterized in several complexes between MBP and carbohydrate; all indicate that the major interaction between carbohydrate and collectin is the binding of two adjacent carbohydrate hydroxyl group to a collectin calcium ion.	Carbohydrates	156-168	myelin basic protein	Homo sapiens	86-89
11045608-6	2000	Carbohydrate binding has been structurally characterized in several complexes between MBP and carbohydrate; all indicate that the major interaction between carbohydrate and collectin is the binding of two adjacent carbohydrate hydroxyl group to a collectin calcium ion.	carbohydrate hydroxyl	214-235	myelin basic protein	Homo sapiens	86-89
11045608-6	2000	Carbohydrate binding has been structurally characterized in several complexes between MBP and carbohydrate; all indicate that the major interaction between carbohydrate and collectin is the binding of two adjacent carbohydrate hydroxyl group to a collectin calcium ion.	Calcium	257-264	myelin basic protein	Homo sapiens	86-89
10961665-0	2000	Glatiramer acetate (copolymer-1)-specific, human T cell lines: cytokine profile and suppression of T cell lines reactive against myelin basic protein.	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	129-149
10955696-9	2000	Immunoblot inhibition assays using MBP-rHev b 8 as inhibitor confirmed the presence of latex profilin in the NRL extract.	latex profilin	87-101	myelin basic protein	Homo sapiens	35-38
10955696-10	2000	IgE binding to the native latex profilin could be completely inhibited by the MBP-rHev b 8.	Latex	26-31	myelin basic protein	Homo sapiens	78-81
11003134-2	2000	In the present report, a linear analogue and a series of cyclic semi-mimetic peptides were designed and synthesized based on the human myelin basic protein (MBP(87-99)) epitope (Val87-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro90) and on Copolymer I (a mixture of random polymers of Ala, Gln, Lys and Tyr used to treat MS).	Alanine	287-290	myelin basic protein	Homo sapiens	135-155
11003134-2	2000	In the present report, a linear analogue and a series of cyclic semi-mimetic peptides were designed and synthesized based on the human myelin basic protein (MBP(87-99)) epitope (Val87-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro90) and on Copolymer I (a mixture of random polymers of Ala, Gln, Lys and Tyr used to treat MS).	Alanine	287-290	myelin basic protein	Homo sapiens	157-160
11003134-2	2000	In the present report, a linear analogue and a series of cyclic semi-mimetic peptides were designed and synthesized based on the human myelin basic protein (MBP(87-99)) epitope (Val87-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro90) and on Copolymer I (a mixture of random polymers of Ala, Gln, Lys and Tyr used to treat MS).	Glutamine	292-295	myelin basic protein	Homo sapiens	135-155
11003134-2	2000	In the present report, a linear analogue and a series of cyclic semi-mimetic peptides were designed and synthesized based on the human myelin basic protein (MBP(87-99)) epitope (Val87-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro90) and on Copolymer I (a mixture of random polymers of Ala, Gln, Lys and Tyr used to treat MS).	Glutamine	292-295	myelin basic protein	Homo sapiens	157-160
11003134-2	2000	In the present report, a linear analogue and a series of cyclic semi-mimetic peptides were designed and synthesized based on the human myelin basic protein (MBP(87-99)) epitope (Val87-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro90) and on Copolymer I (a mixture of random polymers of Ala, Gln, Lys and Tyr used to treat MS).	Lysine	196-199	myelin basic protein	Homo sapiens	135-155
11003134-2	2000	In the present report, a linear analogue and a series of cyclic semi-mimetic peptides were designed and synthesized based on the human myelin basic protein (MBP(87-99)) epitope (Val87-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro90) and on Copolymer I (a mixture of random polymers of Ala, Gln, Lys and Tyr used to treat MS).	Lysine	196-199	myelin basic protein	Homo sapiens	157-160
11003134-2	2000	In the present report, a linear analogue and a series of cyclic semi-mimetic peptides were designed and synthesized based on the human myelin basic protein (MBP(87-99)) epitope (Val87-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro90) and on Copolymer I (a mixture of random polymers of Ala, Gln, Lys and Tyr used to treat MS).	Tyrosine	305-308	myelin basic protein	Homo sapiens	135-155
11003134-2	2000	In the present report, a linear analogue and a series of cyclic semi-mimetic peptides were designed and synthesized based on the human myelin basic protein (MBP(87-99)) epitope (Val87-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro90) and on Copolymer I (a mixture of random polymers of Ala, Gln, Lys and Tyr used to treat MS).	Tyrosine	305-308	myelin basic protein	Homo sapiens	157-160
10903744-4	2000	The mutations Gly25-->Asp and Gly28-->Glu disrupt the disulfide-bonding arrangement of the protein and cause at least a 5-fold increase in the half-time of secretion of MBP compared with wild-type rat serum MBP.	Aspartic Acid	25-28	myelin basic protein	Homo sapiens	175-178
10903744-4	2000	The mutations Gly25-->Asp and Gly28-->Glu disrupt the disulfide-bonding arrangement of the protein and cause at least a 5-fold increase in the half-time of secretion of MBP compared with wild-type rat serum MBP.	Glutamic Acid	44-47	myelin basic protein	Homo sapiens	175-178
10903744-4	2000	The mutations Gly25-->Asp and Gly28-->Glu disrupt the disulfide-bonding arrangement of the protein and cause at least a 5-fold increase in the half-time of secretion of MBP compared with wild-type rat serum MBP.	Glutamic Acid	44-47	myelin basic protein	Homo sapiens	213-216
10903744-4	2000	The mutations Gly25-->Asp and Gly28-->Glu disrupt the disulfide-bonding arrangement of the protein and cause at least a 5-fold increase in the half-time of secretion of MBP compared with wild-type rat serum MBP.	Disulfides	60-69	myelin basic protein	Homo sapiens	175-178
10962541-0	2000	Enhanced T cell responsiveness to citrulline-containing myelin basic protein in multiple sclerosis patients.	Citrulline	34-44	myelin basic protein	Homo sapiens	56-76
10962541-6	2000	Here, we examined the frequency and peptide specificity of MBP-C8-specific TCL generated with MBP-C8 in MS patients and controls.	Triclosan	75-78	myelin basic protein	Homo sapiens	59-62
10962541-6	2000	Here, we examined the frequency and peptide specificity of MBP-C8-specific TCL generated with MBP-C8 in MS patients and controls.	Triclosan	75-78	myelin basic protein	Homo sapiens	94-97
10869185-10	2000	Actin binding to MBP decreased the labeling of MBP by the hydrophobic photolabel 3-(trifluoromethyl)-3-(m-[(125)I]iodophenyl)diazirine (TID), indicating that it decreased the hydrophobic interactions of MBP with the bilayer.	3-(trifluoromethyl)-3-(m-[(125)i]iodophenyl)diazirine	81-134	myelin basic protein	Homo sapiens	17-20
10869185-10	2000	Actin binding to MBP decreased the labeling of MBP by the hydrophobic photolabel 3-(trifluoromethyl)-3-(m-[(125)I]iodophenyl)diazirine (TID), indicating that it decreased the hydrophobic interactions of MBP with the bilayer.	3-(trifluoromethyl)-3-(m-[(125)i]iodophenyl)diazirine	81-134	myelin basic protein	Homo sapiens	47-50
10869185-10	2000	Actin binding to MBP decreased the labeling of MBP by the hydrophobic photolabel 3-(trifluoromethyl)-3-(m-[(125)I]iodophenyl)diazirine (TID), indicating that it decreased the hydrophobic interactions of MBP with the bilayer.	3-(trifluoromethyl)-3-(m-[(125)i]iodophenyl)diazirine	81-134	myelin basic protein	Homo sapiens	47-50
10880969-3	2000	Mass spectrometry and peptide sequencing allowed us to identify serine 164 of MBP as the unique site phosphorylated by KIS.	Serine	64-70	myelin basic protein	Homo sapiens	78-81
10846076-6	2000	When expressed as a maltose binding protein (MBP) fusion protein by bacteria, the NS protease exhibited activity both in the bacteria and in vitro following purification when denatured and refolded in the presence of Zn.	Zinc	217-219	myelin basic protein	Homo sapiens	20-43
10846076-6	2000	When expressed as a maltose binding protein (MBP) fusion protein by bacteria, the NS protease exhibited activity both in the bacteria and in vitro following purification when denatured and refolded in the presence of Zn.	Zinc	217-219	myelin basic protein	Homo sapiens	45-48
10846076-8	2000	Expression of individual domains within the protease as MBP fusions and analysis by a Zn(65) binding assay revealed two Zn binding domains: one located at a predicted metal binding motif beginning at Cys1175 and the other one close to the cleavage site.	Zinc	120-122	myelin basic protein	Homo sapiens	56-59
10861011-9	2000	Interestingly, although there was no proliferative cross-reaction, about 10% of the COP-reactive TCL responded to MBP by secretion of small amounts of IL-4 or IFN-gamma, depending on the cytokine profile of the TCL.	Triclosan	97-100	myelin basic protein	Homo sapiens	114-117
10747894-3	2000	Here we demonstrate by protein sequencing and mass spectrometry that all arginines in the C-terminal arginine-glycine (RG) dipeptide repeats of the human Sm proteins D1 and D3, isolated from HeLa small nuclear ribonucleoproteins, contain symmetrical dimethylarginines (sDMAs), a posttranslational modification thus far only identified in the myelin basic protein.	Arginine	73-82	myelin basic protein	Homo sapiens	342-362
12903484-3	2000	Maltose-binding-protein (MBP)-NS3/NS3-4A fusion protein expression were induced by adding isopropyl-beta-D-thiogalacto-pyranoside (IPTG) and purified by affinity chromatography.	Isopropyl Thiogalactoside	90-129	myelin basic protein	Homo sapiens	0-23
12903484-3	2000	Maltose-binding-protein (MBP)-NS3/NS3-4A fusion protein expression were induced by adding isopropyl-beta-D-thiogalacto-pyranoside (IPTG) and purified by affinity chromatography.	Isopropyl Thiogalactoside	90-129	myelin basic protein	Homo sapiens	25-28
12903484-3	2000	Maltose-binding-protein (MBP)-NS3/NS3-4A fusion protein expression were induced by adding isopropyl-beta-D-thiogalacto-pyranoside (IPTG) and purified by affinity chromatography.	Isopropyl Thiogalactoside	131-135	myelin basic protein	Homo sapiens	0-23
12903484-3	2000	Maltose-binding-protein (MBP)-NS3/NS3-4A fusion protein expression were induced by adding isopropyl-beta-D-thiogalacto-pyranoside (IPTG) and purified by affinity chromatography.	Isopropyl Thiogalactoside	131-135	myelin basic protein	Homo sapiens	25-28
10821702-6	2000	In contrast, at saturating ATP, a full viscosity effect on k(cat)/K(m) for MBP was apparent (k(cat)/K(m(MBP)) = 2.4 +/- 1 microM(-1) s(-1), k(cat)/K(m(MBP))(eta) = 1.0 +/- 0.1), while no viscosity effect was observed on k(cat)/K(m) for the phosphorylation of ERKtide (k(cat)/K(m(ERKtide)) = (4 +/- 2) x 10(-3) microM(-1) s(-1), k(cat)/K(m(ERKtide))(eta) = -0.02 +/- 0.02).	Adenosine Triphosphate	27-30	myelin basic protein	Homo sapiens	75-78
10821702-6	2000	In contrast, at saturating ATP, a full viscosity effect on k(cat)/K(m) for MBP was apparent (k(cat)/K(m(MBP)) = 2.4 +/- 1 microM(-1) s(-1), k(cat)/K(m(MBP))(eta) = 1.0 +/- 0.1), while no viscosity effect was observed on k(cat)/K(m) for the phosphorylation of ERKtide (k(cat)/K(m(ERKtide)) = (4 +/- 2) x 10(-3) microM(-1) s(-1), k(cat)/K(m(ERKtide))(eta) = -0.02 +/- 0.02).	Adenosine Triphosphate	27-30	myelin basic protein	Homo sapiens	104-107
10821702-6	2000	In contrast, at saturating ATP, a full viscosity effect on k(cat)/K(m) for MBP was apparent (k(cat)/K(m(MBP)) = 2.4 +/- 1 microM(-1) s(-1), k(cat)/K(m(MBP))(eta) = 1.0 +/- 0.1), while no viscosity effect was observed on k(cat)/K(m) for the phosphorylation of ERKtide (k(cat)/K(m(ERKtide)) = (4 +/- 2) x 10(-3) microM(-1) s(-1), k(cat)/K(m(ERKtide))(eta) = -0.02 +/- 0.02).	Adenosine Triphosphate	27-30	myelin basic protein	Homo sapiens	104-107
10821702-6	2000	In contrast, at saturating ATP, a full viscosity effect on k(cat)/K(m) for MBP was apparent (k(cat)/K(m(MBP)) = 2.4 +/- 1 microM(-1) s(-1), k(cat)/K(m(MBP))(eta) = 1.0 +/- 0.1), while no viscosity effect was observed on k(cat)/K(m) for the phosphorylation of ERKtide (k(cat)/K(m(ERKtide)) = (4 +/- 2) x 10(-3) microM(-1) s(-1), k(cat)/K(m(ERKtide))(eta) = -0.02 +/- 0.02).	erktide	259-266	myelin basic protein	Homo sapiens	75-78
10821702-6	2000	In contrast, at saturating ATP, a full viscosity effect on k(cat)/K(m) for MBP was apparent (k(cat)/K(m(MBP)) = 2.4 +/- 1 microM(-1) s(-1), k(cat)/K(m(MBP))(eta) = 1.0 +/- 0.1), while no viscosity effect was observed on k(cat)/K(m) for the phosphorylation of ERKtide (k(cat)/K(m(ERKtide)) = (4 +/- 2) x 10(-3) microM(-1) s(-1), k(cat)/K(m(ERKtide))(eta) = -0.02 +/- 0.02).	erktide	259-266	myelin basic protein	Homo sapiens	104-107
10821702-6	2000	In contrast, at saturating ATP, a full viscosity effect on k(cat)/K(m) for MBP was apparent (k(cat)/K(m(MBP)) = 2.4 +/- 1 microM(-1) s(-1), k(cat)/K(m(MBP))(eta) = 1.0 +/- 0.1), while no viscosity effect was observed on k(cat)/K(m) for the phosphorylation of ERKtide (k(cat)/K(m(ERKtide)) = (4 +/- 2) x 10(-3) microM(-1) s(-1), k(cat)/K(m(ERKtide))(eta) = -0.02 +/- 0.02).	erktide	259-266	myelin basic protein	Homo sapiens	104-107
10821702-6	2000	In contrast, at saturating ATP, a full viscosity effect on k(cat)/K(m) for MBP was apparent (k(cat)/K(m(MBP)) = 2.4 +/- 1 microM(-1) s(-1), k(cat)/K(m(MBP))(eta) = 1.0 +/- 0.1), while no viscosity effect was observed on k(cat)/K(m) for the phosphorylation of ERKtide (k(cat)/K(m(ERKtide)) = (4 +/- 2) x 10(-3) microM(-1) s(-1), k(cat)/K(m(ERKtide))(eta) = -0.02 +/- 0.02).	erktide	279-286	myelin basic protein	Homo sapiens	75-78
10821702-6	2000	In contrast, at saturating ATP, a full viscosity effect on k(cat)/K(m) for MBP was apparent (k(cat)/K(m(MBP)) = 2.4 +/- 1 microM(-1) s(-1), k(cat)/K(m(MBP))(eta) = 1.0 +/- 0.1), while no viscosity effect was observed on k(cat)/K(m) for the phosphorylation of ERKtide (k(cat)/K(m(ERKtide)) = (4 +/- 2) x 10(-3) microM(-1) s(-1), k(cat)/K(m(ERKtide))(eta) = -0.02 +/- 0.02).	erktide	279-286	myelin basic protein	Homo sapiens	104-107
10821702-6	2000	In contrast, at saturating ATP, a full viscosity effect on k(cat)/K(m) for MBP was apparent (k(cat)/K(m(MBP)) = 2.4 +/- 1 microM(-1) s(-1), k(cat)/K(m(MBP))(eta) = 1.0 +/- 0.1), while no viscosity effect was observed on k(cat)/K(m) for the phosphorylation of ERKtide (k(cat)/K(m(ERKtide)) = (4 +/- 2) x 10(-3) microM(-1) s(-1), k(cat)/K(m(ERKtide))(eta) = -0.02 +/- 0.02).	erktide	279-286	myelin basic protein	Homo sapiens	104-107
10821702-9	2000	Furthermore, MBP binds to the ERK2 x ATP complex at least 1500-fold more tightly than does ERKtide (K(d(ERKtide)) >/= 1.5 mM).	Adenosine Triphosphate	37-40	myelin basic protein	Homo sapiens	13-16
10821702-9	2000	Furthermore, MBP binds to the ERK2 x ATP complex at least 1500-fold more tightly than does ERKtide (K(d(ERKtide)) >/= 1.5 mM).	erktide	104-111	myelin basic protein	Homo sapiens	13-16
10821702-10	2000	The dramatically higher catalytic efficiency of MBP in comparison to that of ERKtide ( approximately 600-fold difference) is largely attributable to the slow dissociation rate of MBP (</=1.2 s(-1)) versus that of the synthetic peptide (>/=56 s(-1)), from the ERK2 active site.	erktide	77-84	myelin basic protein	Homo sapiens	48-51
10821702-10	2000	The dramatically higher catalytic efficiency of MBP in comparison to that of ERKtide ( approximately 600-fold difference) is largely attributable to the slow dissociation rate of MBP (</=1.2 s(-1)) versus that of the synthetic peptide (>/=56 s(-1)), from the ERK2 active site.	erktide	77-84	myelin basic protein	Homo sapiens	179-182
10821702-10	2000	The dramatically higher catalytic efficiency of MBP in comparison to that of ERKtide ( approximately 600-fold difference) is largely attributable to the slow dissociation rate of MBP (</=1.2 s(-1)) versus that of the synthetic peptide (>/=56 s(-1)), from the ERK2 active site.	Peptides	230-237	myelin basic protein	Homo sapiens	48-51
10821702-10	2000	The dramatically higher catalytic efficiency of MBP in comparison to that of ERKtide ( approximately 600-fold difference) is largely attributable to the slow dissociation rate of MBP (</=1.2 s(-1)) versus that of the synthetic peptide (>/=56 s(-1)), from the ERK2 active site.	Peptides	230-237	myelin basic protein	Homo sapiens	179-182
10818225-3	2000	The myelin basic protein degradation assay was used to demonstrate that hydroxamate inhibitors of matrix metalloproteinases (MMPs) were also inhibitors of ADAM-10.	hydroxamate	72-83	myelin basic protein	Homo sapiens	4-24
10797546-6	2000	Activation of two well-characterized signaling pathways that differentially affect microtubule and actin filament stability in membrane sheets resulted in an apparent massive lateral movement of cholesterol molecules away from membrane regions overlying internal MBP domains to membrane tracts directly overlying cytoplasmic cytoskeletal veins.	Cholesterol	195-206	myelin basic protein	Homo sapiens	263-266
10799506-2	2000	Using truncated recombinant HBHA forms and hybrid proteins containing HBHA repeats grafted onto the Escherichia coli maltose-binding protein (MBP), we found that these repeats are responsible for heparin binding.	Heparin	196-203	myelin basic protein	Homo sapiens	142-145
10820009-6	2000	Methylation of Arg 106 in bovine MBP (Arg 107 in human), a naturally occurring modification of MBP, has been shown to affect the deimination of arginyl residues in the present study.	Arginine	15-18	myelin basic protein	Homo sapiens	95-98
10820009-6	2000	Methylation of Arg 106 in bovine MBP (Arg 107 in human), a naturally occurring modification of MBP, has been shown to affect the deimination of arginyl residues in the present study.	Arginine	38-41	myelin basic protein	Homo sapiens	95-98
10820009-6	2000	Methylation of Arg 106 in bovine MBP (Arg 107 in human), a naturally occurring modification of MBP, has been shown to affect the deimination of arginyl residues in the present study.	arginyl	144-151	myelin basic protein	Homo sapiens	95-98
10775436-0	2000	p-Cresol sulfate is the dominant component of urinary myelin basic protein like material.	4-cresol sulfate	0-16	myelin basic protein	Homo sapiens	54-74
10911622-1	2000	The pMAL vectors provide a method for purifying proteins from cloned genes by fusing them to maltose-binding protein (MBP, product of malE), which binds to amylose.	Amylose	156-163	myelin basic protein	Homo sapiens	93-116
10911622-1	2000	The pMAL vectors provide a method for purifying proteins from cloned genes by fusing them to maltose-binding protein (MBP, product of malE), which binds to amylose.	Amylose	156-163	myelin basic protein	Homo sapiens	118-121
10770805-5	2000	In addition, MK16 inhibited interleukin 2 secretion by two transfectants that expressed human MBP-specific T cell receptors.	mk16	13-17	myelin basic protein	Homo sapiens	94-97
10722720-1	2000	We found that antitumor drugs such as cytotrienin A, camptothecin, taxol, and 5-fluorouracil induced the activation of a 36-kDa protein kinase (p36 myelin basic protein (MBP) kinase) during apoptosis in human promyelocytic leukemia HL-60 cells.	cytotrienin A	38-51	myelin basic protein	Homo sapiens	170-173
10722720-1	2000	We found that antitumor drugs such as cytotrienin A, camptothecin, taxol, and 5-fluorouracil induced the activation of a 36-kDa protein kinase (p36 myelin basic protein (MBP) kinase) during apoptosis in human promyelocytic leukemia HL-60 cells.	Camptothecin	53-65	myelin basic protein	Homo sapiens	170-173
10722720-1	2000	We found that antitumor drugs such as cytotrienin A, camptothecin, taxol, and 5-fluorouracil induced the activation of a 36-kDa protein kinase (p36 myelin basic protein (MBP) kinase) during apoptosis in human promyelocytic leukemia HL-60 cells.	Paclitaxel	67-72	myelin basic protein	Homo sapiens	170-173
10722720-1	2000	We found that antitumor drugs such as cytotrienin A, camptothecin, taxol, and 5-fluorouracil induced the activation of a 36-kDa protein kinase (p36 myelin basic protein (MBP) kinase) during apoptosis in human promyelocytic leukemia HL-60 cells.	Fluorouracil	78-92	myelin basic protein	Homo sapiens	170-173
10722720-4	2000	In cytotrienin A-sensitive cell lines, we observed a strong activation of p36 MBP kinase by cleavage of the C-terminal regulatory domain of full-length MST/Krs proteins by caspase-3.	cytotrienin A	3-16	myelin basic protein	Homo sapiens	78-81
10731149-4	2000	Adenosine triphosphate arrests maturation of SCs in an immature morphological stage and prevents expression of O4, myelin basic protein, and the formation of myelin.	Adenosine Triphosphate	0-22	myelin basic protein	Homo sapiens	115-135
16233148-3	2001	We developed a large-scale preparation system for recombinant human GnT-I (hGnT-I) using the maltose binding protein (MBP) fusion system to facilitate the chemoenzymatic route for complex-type N-linked glycan synthesis.	n-linked glycan	193-208	myelin basic protein	Homo sapiens	118-121
16233148-4	2001	MBP-fused GnT-I was purified by affinity chromatography on an amylose resin column.	Amylose	62-69	myelin basic protein	Homo sapiens	0-3
16233148-5	2001	The relative activity of MBP-fused GnT-I toward high-mannose-type N-linked oligosaccharides was 100% for Man5GlcNAc2, 52% for Man3GlcNAc2, 17% for Man6GlcNAc2.	Mannose	53-60	myelin basic protein	Homo sapiens	25-28
16233148-5	2001	The relative activity of MBP-fused GnT-I toward high-mannose-type N-linked oligosaccharides was 100% for Man5GlcNAc2, 52% for Man3GlcNAc2, 17% for Man6GlcNAc2.	n-linked oligosaccharides	66-91	myelin basic protein	Homo sapiens	25-28
16233148-5	2001	The relative activity of MBP-fused GnT-I toward high-mannose-type N-linked oligosaccharides was 100% for Man5GlcNAc2, 52% for Man3GlcNAc2, 17% for Man6GlcNAc2.	mannosyl(5)-N-acetyl(2)-glucose	105-116	myelin basic protein	Homo sapiens	25-28
16233148-5	2001	The relative activity of MBP-fused GnT-I toward high-mannose-type N-linked oligosaccharides was 100% for Man5GlcNAc2, 52% for Man3GlcNAc2, 17% for Man6GlcNAc2.	Man(3)GlcNAc(2)	126-137	myelin basic protein	Homo sapiens	25-28
16233148-5	2001	The relative activity of MBP-fused GnT-I toward high-mannose-type N-linked oligosaccharides was 100% for Man5GlcNAc2, 52% for Man3GlcNAc2, 17% for Man6GlcNAc2.	mannosyl(6)-N-acetyl(2)glucose	147-158	myelin basic protein	Homo sapiens	25-28
16233148-7	2001	The optimum temperature for MBP-fused GnT-I activity was 40 degrees C, but the enzyme was active between 0-70 degrees C. Mn2+ and Co2+ were critical for the enzyme activity, while Zn2+ and Ca2+ inhibited the activity.	Manganese(2+)	121-125	myelin basic protein	Homo sapiens	28-31
16233148-7	2001	The optimum temperature for MBP-fused GnT-I activity was 40 degrees C, but the enzyme was active between 0-70 degrees C. Mn2+ and Co2+ were critical for the enzyme activity, while Zn2+ and Ca2+ inhibited the activity.	Cobalt(2+)	130-134	myelin basic protein	Homo sapiens	28-31
16233148-7	2001	The optimum temperature for MBP-fused GnT-I activity was 40 degrees C, but the enzyme was active between 0-70 degrees C. Mn2+ and Co2+ were critical for the enzyme activity, while Zn2+ and Ca2+ inhibited the activity.	Zinc	180-184	myelin basic protein	Homo sapiens	28-31
16233148-9	2001	Immobilization of MBP-fused GnT-I on the amylose resin led to an 80% yield of the high mannose-type-of oligosaccharide.	Amylose	41-48	myelin basic protein	Homo sapiens	18-21
16233148-9	2001	Immobilization of MBP-fused GnT-I on the amylose resin led to an 80% yield of the high mannose-type-of oligosaccharide.	Mannose	87-94	myelin basic protein	Homo sapiens	18-21
16233148-9	2001	Immobilization of MBP-fused GnT-I on the amylose resin led to an 80% yield of the high mannose-type-of oligosaccharide.	type-of oligosaccharide	95-118	myelin basic protein	Homo sapiens	18-21
10776827-9	2000	Glatiramer acetate, the acetate salt of a mixture synthetic polypeptides thought to mimic the myelin basic protein showed a significant positive results in reducing the relapse rate in patients with RR-MS.	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	94-114
10741389-6	2000	However, a high proportion of animals injected with IL-4 + DEX-treated lines became refractory to the development of EAE after immunization with MBP; that is, it was possible to induce resistance to active EAE without prior episodes of disease.	Dexamethasone	59-62	myelin basic protein	Homo sapiens	145-148
10692326-0	2000	Kinetic and structural study of the interaction of myelin basic protein with dipalmitoylphosphatidylglycerol layers.	1,2-dipalmitoylphosphatidylglycerol	77-108	myelin basic protein	Homo sapiens	51-71
10776827-9	2000	Glatiramer acetate, the acetate salt of a mixture synthetic polypeptides thought to mimic the myelin basic protein showed a significant positive results in reducing the relapse rate in patients with RR-MS.	acetate salt	24-36	myelin basic protein	Homo sapiens	94-114
10675299-2	2000	Reduction in cationicity of MBP, especially due to conversion of positively charged arginine residues to uncharged citrulline (Cit), has been found to be associated with multiple sclerosis (MS).	Arginine	84-92	myelin basic protein	Homo sapiens	28-31
10938826-0	2000	ABA activation of an MBP kinase in Pisum sativum epidermal peels correlates with stomatal responses to ABA.	Abscisic Acid	0-3	myelin basic protein	Homo sapiens	21-24
10938826-0	2000	ABA activation of an MBP kinase in Pisum sativum epidermal peels correlates with stomatal responses to ABA.	Abscisic Acid	103-106	myelin basic protein	Homo sapiens	21-24
10675299-2	2000	Reduction in cationicity of MBP, especially due to conversion of positively charged arginine residues to uncharged citrulline (Cit), has been found to be associated with multiple sclerosis (MS).	Citrulline	115-125	myelin basic protein	Homo sapiens	28-31
10675299-2	2000	Reduction in cationicity of MBP, especially due to conversion of positively charged arginine residues to uncharged citrulline (Cit), has been found to be associated with multiple sclerosis (MS).	Citrulline	127-130	myelin basic protein	Homo sapiens	28-31
10675299-3	2000	Here, the interactions of an anionic phosphatidylserine/monosialoganglioside-G(M1) (4:1, w:w) lipid monolayer with 18.5-kDa MBP preparations from age-matched adult humans without MS (no Cit residues), with chronic MS (6 Cit), and with acute Marburg-type MS (18 Cit) were studied by transmission and ultralow dose scanning transmission electron microscopy under cryogenic conditions.	Phosphatidylserines	37-55	myelin basic protein	Homo sapiens	124-127
10675299-3	2000	Here, the interactions of an anionic phosphatidylserine/monosialoganglioside-G(M1) (4:1, w:w) lipid monolayer with 18.5-kDa MBP preparations from age-matched adult humans without MS (no Cit residues), with chronic MS (6 Cit), and with acute Marburg-type MS (18 Cit) were studied by transmission and ultralow dose scanning transmission electron microscopy under cryogenic conditions.	sialogangliosides	56-76	myelin basic protein	Homo sapiens	124-127
10675299-6	2000	The least cationic Marburg MBP-Cit(18) formed the most open protein-lipid complex.	Citrulline	31-34	myelin basic protein	Homo sapiens	27-30
10594925-6	2000	MBP-induced proliferation was inhibited by suramin at concentrations known to block the fibroblast growth factor receptor (FGFR), whereas neither MBP(1-44), MBP(88-151) nor MBP(152-167) were affected.	Suramin	43-50	myelin basic protein	Homo sapiens	0-3
10626670-2	2000	We reported previously that TCV with myelin basic protein (MBP) reactive T cell clones in multiple sclerosis (MS) patients induced T cell immune responses, resulting in a clonal depletion of MBP reactive T cells in all patients.	Trichloroethylene	28-31	myelin basic protein	Homo sapiens	37-57
10626670-2	2000	We reported previously that TCV with myelin basic protein (MBP) reactive T cell clones in multiple sclerosis (MS) patients induced T cell immune responses, resulting in a clonal depletion of MBP reactive T cells in all patients.	Trichloroethylene	28-31	myelin basic protein	Homo sapiens	59-62
10626670-2	2000	We reported previously that TCV with myelin basic protein (MBP) reactive T cell clones in multiple sclerosis (MS) patients induced T cell immune responses, resulting in a clonal depletion of MBP reactive T cells in all patients.	Trichloroethylene	28-31	myelin basic protein	Homo sapiens	191-194
10606768-1	2000	Autophosphorylation of recombinant mitogen-activated protein kinase (MAPK) on Tyr was found to be several-fold stimulated at weakly acidic pH (5.5-6.0), whereas the phosphorylation of a protein substrate, myelin basic protein, was greatly inhibited at pH below 6.	Tyrosine	78-81	myelin basic protein	Homo sapiens	205-225
10594925-8	2000	Treatment of astrocytes with MBP and MBP(152-167) caused a modest and transitory elevation of intracellular calcium, whereas treatment with MBP(1-44) resulted in a substantial and sustained increase in intracellular calcium.	Calcium	108-115	myelin basic protein	Homo sapiens	29-32
10594925-8	2000	Treatment of astrocytes with MBP and MBP(152-167) caused a modest and transitory elevation of intracellular calcium, whereas treatment with MBP(1-44) resulted in a substantial and sustained increase in intracellular calcium.	Calcium	108-115	myelin basic protein	Homo sapiens	37-40
10594925-8	2000	Treatment of astrocytes with MBP and MBP(152-167) caused a modest and transitory elevation of intracellular calcium, whereas treatment with MBP(1-44) resulted in a substantial and sustained increase in intracellular calcium.	Calcium	108-115	myelin basic protein	Homo sapiens	37-40
10594925-8	2000	Treatment of astrocytes with MBP and MBP(152-167) caused a modest and transitory elevation of intracellular calcium, whereas treatment with MBP(1-44) resulted in a substantial and sustained increase in intracellular calcium.	Calcium	216-223	myelin basic protein	Homo sapiens	29-32
10906770-3	2000	Second, rp66 with Ser-Ser at the N-terminus was produced as a fusion protein with maltose-binding protein containing a factor Xa site between the two proteins (MBP-Ser-Ser-rp66) and was released from the fusion protein by factor Xa (Ser-Ser-rp66).	Maltose	82-89	myelin basic protein	Homo sapiens	160-163
10906770-6	2000	MBP-Ser-Ser-rp66 and Met-Gly-rp66 were readily purified in sufficient amounts for labeling with 2, 4-dinitrophenyl groups and beta-D-galactosidase from E. coli, but pol-rp66 and Ser-Ser-rp66 were not for enzyme-labeling.	Serine	4-7	myelin basic protein	Homo sapiens	0-3
10906770-6	2000	MBP-Ser-Ser-rp66 and Met-Gly-rp66 were readily purified in sufficient amounts for labeling with 2, 4-dinitrophenyl groups and beta-D-galactosidase from E. coli, but pol-rp66 and Ser-Ser-rp66 were not for enzyme-labeling.	Serine	8-11	myelin basic protein	Homo sapiens	0-3
10906770-9	2000	Among various combined uses of the two labeled preparations, the uses of 2,4-dinitrophenylated MBP-Ser-Ser-rp66 and pol-rp66 with beta-D-galactosidase-labeled Met-Gly-rp66 showed the highest (99.8%) and the second highest (99.5%) specificities, which were higher than that with the labeled preparations used in the previous study (98.	Serine	99-102	myelin basic protein	Homo sapiens	95-98
10906770-6	2000	MBP-Ser-Ser-rp66 and Met-Gly-rp66 were readily purified in sufficient amounts for labeling with 2, 4-dinitrophenyl groups and beta-D-galactosidase from E. coli, but pol-rp66 and Ser-Ser-rp66 were not for enzyme-labeling.	Serine	8-11	myelin basic protein	Homo sapiens	0-3
10906770-9	2000	Among various combined uses of the two labeled preparations, the uses of 2,4-dinitrophenylated MBP-Ser-Ser-rp66 and pol-rp66 with beta-D-galactosidase-labeled Met-Gly-rp66 showed the highest (99.8%) and the second highest (99.5%) specificities, which were higher than that with the labeled preparations used in the previous study (98.	Serine	103-106	myelin basic protein	Homo sapiens	95-98
10906770-6	2000	MBP-Ser-Ser-rp66 and Met-Gly-rp66 were readily purified in sufficient amounts for labeling with 2, 4-dinitrophenyl groups and beta-D-galactosidase from E. coli, but pol-rp66 and Ser-Ser-rp66 were not for enzyme-labeling.	Serine	8-11	myelin basic protein	Homo sapiens	0-3
10578050-1	1999	Serum mannan binding protein (MBP), a mannose/N-acetylglusosamine-specific lectin, is important in innate immunity.	Mannose	38-45	myelin basic protein	Homo sapiens	6-28
10561588-3	1999	Upon binding of maltose, MBP undergoes a large structural change that closes the binding cleft, i.e. the distance between its two domains decreases.	Maltose	16-23	myelin basic protein	Homo sapiens	25-28
10561588-5	1999	We have investigated the dynamic properties of MBP in its different states using time-resolved tryptophan fluorescence anisotropy.	Tryptophan	95-105	myelin basic protein	Homo sapiens	47-50
10578050-1	1999	Serum mannan binding protein (MBP), a mannose/N-acetylglusosamine-specific lectin, is important in innate immunity.	Mannose	38-45	myelin basic protein	Homo sapiens	30-33
10578050-1	1999	Serum mannan binding protein (MBP), a mannose/N-acetylglusosamine-specific lectin, is important in innate immunity.	n-acetylglusosamine	46-65	myelin basic protein	Homo sapiens	6-28
10578050-1	1999	Serum mannan binding protein (MBP), a mannose/N-acetylglusosamine-specific lectin, is important in innate immunity.	n-acetylglusosamine	46-65	myelin basic protein	Homo sapiens	30-33
10934518-4	1999	The traditional method of MBP isolation involves the use of chloroform-ethanol, which would destroy the native form of MBP.	EtOH chloroform	60-78	myelin basic protein	Homo sapiens	26-29
10638201-2	1999	The MBP binds and internizes chylomicrons, triglyceride (TG)-rich VLDL, and VLDL devoid of apo E, but not acetyl LDL, via a domain in apo B48.	Triglycerides	43-55	myelin basic protein	Homo sapiens	4-7
10638201-2	1999	The MBP binds and internizes chylomicrons, triglyceride (TG)-rich VLDL, and VLDL devoid of apo E, but not acetyl LDL, via a domain in apo B48.	Triglycerides	57-59	myelin basic protein	Homo sapiens	4-7
10502300-6	1999	Like Mapk, this protein phosphorylated MBP mostly on threonine residues, but it failed to phosphorylate a peptide (APRTPGGRR) based upon the Thr-97 MAP kinase phosphorylation site in MBP.	Threonine	53-62	myelin basic protein	Homo sapiens	39-42
10502300-8	1999	Our studies also showed a dramatic increase in MBP phosphotransferase activity occurred by 4 days PF that arose from a third kinase that phosphorylated MBP solely on serine residues.	Serine	166-172	myelin basic protein	Homo sapiens	47-50
10502300-8	1999	Our studies also showed a dramatic increase in MBP phosphotransferase activity occurred by 4 days PF that arose from a third kinase that phosphorylated MBP solely on serine residues.	Serine	166-172	myelin basic protein	Homo sapiens	152-155
10545390-5	1999	In contrast, OIND are characterized by similar frequencies of serum IgG antibody responses to MOG-Ig (53%) and MBP (47%), whereas serum IgG responses to MOG-Ig are rare in ONND (3%) and rheumatoid arthritis (10%).	oind	13-17	myelin basic protein	Homo sapiens	111-114
10934518-4	1999	The traditional method of MBP isolation involves the use of chloroform-ethanol, which would destroy the native form of MBP.	EtOH chloroform	60-78	myelin basic protein	Homo sapiens	119-122
10934518-6	1999	The white matter of porcine brain was directly extracted by buffers containing different concentrations of sodium chloride owing to MBP solubilized at high concentration of NaCl.	Sodium Chloride	107-122	myelin basic protein	Homo sapiens	132-135
10934518-7	1999	The MBP was further purified by cation exchange chromatography and buffers containing glycine and salts.	Glycine	86-93	myelin basic protein	Homo sapiens	4-7
10498871-5	1999	Moreover, MT-21 treatment resulted in the activation of a 36 kDa kinase which uses myelin basic protein (MBP) as a substrate.	MT 21	10-15	myelin basic protein	Homo sapiens	83-103
10482574-3	1999	In the present study, we further characterized the AAV Rep68/78 helicase, ATPase, and endonuclease activities by using a maltose binding protein-Rep68 fusion (MBP-Rep68Delta) produced in Escherichia coli cells and Rep78 produced in vitro in a rabbit reticulocyte lysate system.	Maltose	121-128	myelin basic protein	Homo sapiens	159-162
10482574-6	1999	We then determined the ATP concentration needed for optimal MBP-Rep68Delta helicase activity and showed that the helicase is active over a wide range of ATP concentrations.	Adenosine Triphosphate	23-26	myelin basic protein	Homo sapiens	60-63
10482574-6	1999	We then determined the ATP concentration needed for optimal MBP-Rep68Delta helicase activity and showed that the helicase is active over a wide range of ATP concentrations.	Adenosine Triphosphate	153-156	myelin basic protein	Homo sapiens	60-63
10498871-5	1999	Moreover, MT-21 treatment resulted in the activation of a 36 kDa kinase which uses myelin basic protein (MBP) as a substrate.	MT 21	10-15	myelin basic protein	Homo sapiens	105-108
10508402-7	1999	A SHP-1 mutant missing this binding site could, however, still be activated toward phosphorylated myelin basic protein as a substrate at high PA concentrations.	Phosphatidic Acids	142-144	myelin basic protein	Homo sapiens	98-118
10461899-6	1999	It is interesting that the change in MBP phosphorylation was attenuated by the reactive oxygen species scavengers superoxide dismutase and catalase and the nitric oxide synthase inhibitor N-nitro-L-arginine.	Reactive Oxygen Species	79-102	myelin basic protein	Homo sapiens	37-40
10461899-6	1999	It is interesting that the change in MBP phosphorylation was attenuated by the reactive oxygen species scavengers superoxide dismutase and catalase and the nitric oxide synthase inhibitor N-nitro-L-arginine.	Nitroarginine	188-206	myelin basic protein	Homo sapiens	37-40
10461899-7	1999	Removal of extracellular calcium also blocked the changes in MBP phosphorylation.	Calcium	25-32	myelin basic protein	Homo sapiens	61-64
10461899-8	1999	Thus, we propose that during periods of increased neuronal activity, calcium activates axonal nitric oxide synthase, which generates the intercellular messengers nitric oxide and superoxide and regulates the phosphorylation state of MBP by MAPK.	Calcium	69-76	myelin basic protein	Homo sapiens	233-236
10461899-8	1999	Thus, we propose that during periods of increased neuronal activity, calcium activates axonal nitric oxide synthase, which generates the intercellular messengers nitric oxide and superoxide and regulates the phosphorylation state of MBP by MAPK.	Nitric Oxide	94-106	myelin basic protein	Homo sapiens	233-236
10496181-4	1999	After IFNbeta therapy, the production of interleukin-4 was decreased in MBP-stimulated TCL while the secretion of interferon-gamma was increased in unstimulated TCL.	Triclosan	87-90	myelin basic protein	Homo sapiens	72-75
10460230-6	1999	These results indicate that, during periods of increased neuronal activity in area CA1 of the hippocampus, reactive oxygen and nitrogen species are generated, which diffuse to neighboring oligodendrocytes and result in post-translational modifications of MBP, a key structural protein in myelin.	reactive oxygen and nitrogen species	107-143	myelin basic protein	Homo sapiens	255-258
10460230-4	1999	This change was blocked by tetrodotoxin, indicating that axonally generated action potentials were necessary to regulate the phosphorylation state of MBP.	Tetrodotoxin	27-39	myelin basic protein	Homo sapiens	150-153
10485250-4	1999	However, the modified 14C-leucine assay provides a valid measure of MBP"s cytotoxicity and may be useful for analyses of "sticky" cytotoxins.	14c-leucine	22-33	myelin basic protein	Homo sapiens	68-71
10438731-3	1999	Further analysis of the MBP promoter region identified a C/EBP (CCAAT/enhancer-binding protein) consensus binding site 6 bp upstream of the functional GATA-binding site in the MBP gene.	gata	151-155	myelin basic protein	Homo sapiens	24-27
10438731-3	1999	Further analysis of the MBP promoter region identified a C/EBP (CCAAT/enhancer-binding protein) consensus binding site 6 bp upstream of the functional GATA-binding site in the MBP gene.	gata	151-155	myelin basic protein	Homo sapiens	176-179
10438731-6	1999	Furthermore, we have demonstrated that both C/EBPbeta and GATA-1 can bind simultaneously to the C/EBP- and GATA-binding sites in the MBP promoter.	gata	58-62	myelin basic protein	Homo sapiens	133-136
10423454-1	1999	The dynamics of single tryptophan (W) side chain of protease subtilisin Carlsberg (SC) and myelin basic protein (MBP) were used for probing the surface of these proteins.	Tryptophan	23-33	myelin basic protein	Homo sapiens	113-116
10423454-3	1999	Time-resolved fluorescence anisotropy measurements showed that the rotational motion of W is completely unhindered in the case of SC and partially hindered in the case of MBP.	Tungsten	88-89	myelin basic protein	Homo sapiens	171-174
10440902-1	1999	Myelin basic protein (MBP) occurs as a number of charge isomers due to phosphorylation, deamidation, and deimination of arginine to citrulline.	Arginine	120-128	myelin basic protein	Homo sapiens	0-20
10440902-1	1999	Myelin basic protein (MBP) occurs as a number of charge isomers due to phosphorylation, deamidation, and deimination of arginine to citrulline.	Arginine	120-128	myelin basic protein	Homo sapiens	22-25
10440902-1	1999	Myelin basic protein (MBP) occurs as a number of charge isomers due to phosphorylation, deamidation, and deimination of arginine to citrulline.	Citrulline	132-142	myelin basic protein	Homo sapiens	0-20
10440902-1	1999	Myelin basic protein (MBP) occurs as a number of charge isomers due to phosphorylation, deamidation, and deimination of arginine to citrulline.	Citrulline	132-142	myelin basic protein	Homo sapiens	22-25
10423406-4	1999	MBP stimulated 2-fold increases in IL-8 messenger RNA (mRNA) after 1 and 3 h of incubation, which were blocked by pretreatment with actinomycin D.	Dactinomycin	132-145	myelin basic protein	Homo sapiens	0-3
10612091-0	1999	[Myelin basic protein stimulation index of CD 2 cells in the course of steroid treatment].	Steroids	71-78	myelin basic protein	Homo sapiens	1-21
10476077-4	1999	They phosphorylated myelin basic protein in the absence of calcium, were recognized by antibodies directed against human MAP kinases, and were phosphorylated on tyrosine.	Tyrosine	161-169	myelin basic protein	Homo sapiens	20-40
10612091-1	1999	Myelin basic protein CD 2 lymphocyte stimulation index calculated as the proportion of percentage of myelin basic protein stimulated CD 2 lymphocytes to unstimulated CD 2 lymphocytes was evaluated in a group of 23 multiple sclerosis patients in the course of prednisone or methylprednisolone treatment.	Prednisone	259-269	myelin basic protein	Homo sapiens	0-20
10612091-2	1999	After both treatments a decrease of myelin basic protein CD 2 lymphocyte stimulation index was observed, statistically significant after methyloprednisolone medication.	methyloprednisolone	137-156	myelin basic protein	Homo sapiens	36-56
10475609-2	1999	We have now determined that stimulation of human primary and Jurkat T lymphocytes with ionomycin also results in the activation of ERK1 and 2 as determined by; shifts in the mobility of this enzyme on SDS PAGE gels, the binding of an antibody that recognizes only the activated form of this enzyme, and increased ability to phosphorylate myelin basic protein (MBP).	Ionomycin	87-96	myelin basic protein	Homo sapiens	338-358
10475609-2	1999	We have now determined that stimulation of human primary and Jurkat T lymphocytes with ionomycin also results in the activation of ERK1 and 2 as determined by; shifts in the mobility of this enzyme on SDS PAGE gels, the binding of an antibody that recognizes only the activated form of this enzyme, and increased ability to phosphorylate myelin basic protein (MBP).	Ionomycin	87-96	myelin basic protein	Homo sapiens	360-363
10318872-9	1999	Analyses of the biological activities showed that hMBPH had effects similar to hMBP in cell killing and neutrophil (superoxide anion production and interleukin-8 release) and basophil (histamine and leukotriene C4 release) stimulation assays, but usually with reduced potency.	Superoxides	116-132	myelin basic protein	Homo sapiens	50-54
10224325-8	1999	The DNA fragments generated by diepoxides were initially large, their concentration decreasing monotonously from 7 Mbp to less than 1 Mbp and were converted to smaller fragments by 72 h in the course of cell death.	diepoxides	31-41	myelin basic protein	Homo sapiens	115-118
10318872-9	1999	Analyses of the biological activities showed that hMBPH had effects similar to hMBP in cell killing and neutrophil (superoxide anion production and interleukin-8 release) and basophil (histamine and leukotriene C4 release) stimulation assays, but usually with reduced potency.	Histamine	185-194	myelin basic protein	Homo sapiens	50-54
10318872-9	1999	Analyses of the biological activities showed that hMBPH had effects similar to hMBP in cell killing and neutrophil (superoxide anion production and interleukin-8 release) and basophil (histamine and leukotriene C4 release) stimulation assays, but usually with reduced potency.	Leukotriene C4	199-213	myelin basic protein	Homo sapiens	50-54
10320343-2	1999	The 18.5 kDa MBP-C1, the main human adult isoform, has 170 residues and is relatively unmodified, whereas the same isoform can be citrullinated on six arginine residues to create the MBP-C8 (MBP Cit6) isomer.	cit6	195-199	myelin basic protein	Homo sapiens	13-16
10320343-3	1999	MBP Cit6 dominates in MS brain, accounting for 45% rather than 25% of the population of MBP isomers.	cit6	4-8	myelin basic protein	Homo sapiens	0-3
10320343-3	1999	MBP Cit6 dominates in MS brain, accounting for 45% rather than 25% of the population of MBP isomers.	cit6	4-8	myelin basic protein	Homo sapiens	88-91
10320343-4	1999	In the fulminant form of MS, known as Marburg"s Disease, 18 of the 19 arginines in MBP are citrullinated (MBP Cit18).	Arginine	70-79	myelin basic protein	Homo sapiens	83-86
10320343-4	1999	In the fulminant form of MS, known as Marburg"s Disease, 18 of the 19 arginines in MBP are citrullinated (MBP Cit18).	Arginine	70-79	myelin basic protein	Homo sapiens	106-109
10320343-10	1999	Its generation was directly related to the citrulline content of the MBP substrate being 4 times faster in normal MBP Cit6 and 35 times faster in Marburg MBP Cit18 than in normal MBP-C1.	Citrulline	43-53	myelin basic protein	Homo sapiens	69-72
10320343-10	1999	Its generation was directly related to the citrulline content of the MBP substrate being 4 times faster in normal MBP Cit6 and 35 times faster in Marburg MBP Cit18 than in normal MBP-C1.	Citrulline	43-53	myelin basic protein	Homo sapiens	114-117
10320343-10	1999	Its generation was directly related to the citrulline content of the MBP substrate being 4 times faster in normal MBP Cit6 and 35 times faster in Marburg MBP Cit18 than in normal MBP-C1.	Citrulline	43-53	myelin basic protein	Homo sapiens	114-117
10320343-12	1999	We postulate that the generation of MBP peptides, including those that are dominant and encephalitogenic, is directly related to deimination of arginine to citrulline in MBP.	Arginine	144-152	myelin basic protein	Homo sapiens	36-39
10320343-12	1999	We postulate that the generation of MBP peptides, including those that are dominant and encephalitogenic, is directly related to deimination of arginine to citrulline in MBP.	Arginine	144-152	myelin basic protein	Homo sapiens	170-173
10320343-12	1999	We postulate that the generation of MBP peptides, including those that are dominant and encephalitogenic, is directly related to deimination of arginine to citrulline in MBP.	Citrulline	156-166	myelin basic protein	Homo sapiens	36-39
10320343-12	1999	We postulate that the generation of MBP peptides, including those that are dominant and encephalitogenic, is directly related to deimination of arginine to citrulline in MBP.	Citrulline	156-166	myelin basic protein	Homo sapiens	170-173
10207045-5	1999	In an in vitro kinase reaction, the kinase domain of TESK1 underwent autophosphorylation on serine and tyrosine residues and catalyzed phosphorylation of histone H3 and myelin basic protein on serine, threonine, and tyrosine residues.	Serine	92-98	myelin basic protein	Homo sapiens	169-189
10207045-5	1999	In an in vitro kinase reaction, the kinase domain of TESK1 underwent autophosphorylation on serine and tyrosine residues and catalyzed phosphorylation of histone H3 and myelin basic protein on serine, threonine, and tyrosine residues.	Serine	193-199	myelin basic protein	Homo sapiens	169-189
10207045-5	1999	In an in vitro kinase reaction, the kinase domain of TESK1 underwent autophosphorylation on serine and tyrosine residues and catalyzed phosphorylation of histone H3 and myelin basic protein on serine, threonine, and tyrosine residues.	Threonine	201-210	myelin basic protein	Homo sapiens	169-189
10207045-5	1999	In an in vitro kinase reaction, the kinase domain of TESK1 underwent autophosphorylation on serine and tyrosine residues and catalyzed phosphorylation of histone H3 and myelin basic protein on serine, threonine, and tyrosine residues.	Tyrosine	216-224	myelin basic protein	Homo sapiens	169-189
10343652-4	1999	The yield of X-ray-induced DSBs was comparable in all cell lines analyzed, amounting to about 1 x 10(-2) breaks/Mbp/Gy.	dsbs	27-31	myelin basic protein	Homo sapiens	112-115
10082801-1	1999	Myelin basic protein is a water soluble membrane protein which interacts with acidic lipids through some type of hydrophobic interaction in addition to electrostatic interactions.	Water	26-31	myelin basic protein	Homo sapiens	0-20
10028918-11	1999	Furthermore, PMP22, MBP, and P0 protein levels were greatly enhanced by progesterone treatment of the cocultures.	Progesterone	72-84	myelin basic protein	Homo sapiens	20-23
10224465-3	1999	RESULTS: Trypan blue staining, propidium iodide/ CellTrackertrade markGreen staining and incorporation of 14C-leucine assays indicated that MBP damages most cells by 1 h. In contrast, 51Cr and lactic dehydrogenase (LDH) release assays indicated that MBP damages most cells only at 20 h. All five methods indicated that melittin damages nearly all cells by 1 h. To resolve these discrepancies, the procedures were modified.	Propidium	31-47	myelin basic protein	Homo sapiens	140-143
9972872-0	1999	Myelin basic protein and myelin basic protein peptides induce the proliferation of Schwann cells via ganglioside GM1 and the FGF receptor.	G(M1) Ganglioside	101-116	myelin basic protein	Homo sapiens	0-20
9972872-0	1999	Myelin basic protein and myelin basic protein peptides induce the proliferation of Schwann cells via ganglioside GM1 and the FGF receptor.	G(M1) Ganglioside	101-116	myelin basic protein	Homo sapiens	25-45
9972872-1	1999	Myelin basic protein (MBP) and two peptides derived from MBP (MBP(1-44) and MBP(152-167)) stimulated Schwann cell (SC) proliferation in a cAMP-mediated process.	Cyclic AMP	138-142	myelin basic protein	Homo sapiens	0-20
9972872-1	1999	Myelin basic protein (MBP) and two peptides derived from MBP (MBP(1-44) and MBP(152-167)) stimulated Schwann cell (SC) proliferation in a cAMP-mediated process.	Cyclic AMP	138-142	myelin basic protein	Homo sapiens	22-25
9972872-1	1999	Myelin basic protein (MBP) and two peptides derived from MBP (MBP(1-44) and MBP(152-167)) stimulated Schwann cell (SC) proliferation in a cAMP-mediated process.	Cyclic AMP	138-142	myelin basic protein	Homo sapiens	57-60
9972872-1	1999	Myelin basic protein (MBP) and two peptides derived from MBP (MBP(1-44) and MBP(152-167)) stimulated Schwann cell (SC) proliferation in a cAMP-mediated process.	Cyclic AMP	138-142	myelin basic protein	Homo sapiens	57-60
9972872-1	1999	Myelin basic protein (MBP) and two peptides derived from MBP (MBP(1-44) and MBP(152-167)) stimulated Schwann cell (SC) proliferation in a cAMP-mediated process.	Cyclic AMP	138-142	myelin basic protein	Homo sapiens	57-60
9972872-6	1999	The binding of MBP to ganglioside GM1 and the ability of MBP peptides containing homology to the B subunit of cholera toxin (which binds ganglioside GM1) to compete for the binding of a mitogenic peptide (MBP(1-44)) to SC, identified ganglioside GM1 as a second SC receptor.	G(M1) Ganglioside	22-37	myelin basic protein	Homo sapiens	15-18
9972872-6	1999	The binding of MBP to ganglioside GM1 and the ability of MBP peptides containing homology to the B subunit of cholera toxin (which binds ganglioside GM1) to compete for the binding of a mitogenic peptide (MBP(1-44)) to SC, identified ganglioside GM1 as a second SC receptor.	Gangliosides	22-33	myelin basic protein	Homo sapiens	15-18
9972872-6	1999	The binding of MBP to ganglioside GM1 and the ability of MBP peptides containing homology to the B subunit of cholera toxin (which binds ganglioside GM1) to compete for the binding of a mitogenic peptide (MBP(1-44)) to SC, identified ganglioside GM1 as a second SC receptor.	G(M1) Ganglioside	34-37	myelin basic protein	Homo sapiens	15-18
9972872-6	1999	The binding of MBP to ganglioside GM1 and the ability of MBP peptides containing homology to the B subunit of cholera toxin (which binds ganglioside GM1) to compete for the binding of a mitogenic peptide (MBP(1-44)) to SC, identified ganglioside GM1 as a second SC receptor.	Gangliosides	137-148	myelin basic protein	Homo sapiens	57-60
9972872-6	1999	The binding of MBP to ganglioside GM1 and the ability of MBP peptides containing homology to the B subunit of cholera toxin (which binds ganglioside GM1) to compete for the binding of a mitogenic peptide (MBP(1-44)) to SC, identified ganglioside GM1 as a second SC receptor.	Gangliosides	137-148	myelin basic protein	Homo sapiens	57-60
9972872-6	1999	The binding of MBP to ganglioside GM1 and the ability of MBP peptides containing homology to the B subunit of cholera toxin (which binds ganglioside GM1) to compete for the binding of a mitogenic peptide (MBP(1-44)) to SC, identified ganglioside GM1 as a second SC receptor.	G(M1) Ganglioside	149-152	myelin basic protein	Homo sapiens	57-60
9972872-6	1999	The binding of MBP to ganglioside GM1 and the ability of MBP peptides containing homology to the B subunit of cholera toxin (which binds ganglioside GM1) to compete for the binding of a mitogenic peptide (MBP(1-44)) to SC, identified ganglioside GM1 as a second SC receptor.	G(M1) Ganglioside	149-152	myelin basic protein	Homo sapiens	57-60
9972872-7	1999	Based on these results, we conclude that MBP(1-44) and MBP(152-167) associate with ganglioside GM1 and the bFGF receptor respectively to stimulate SC mitosis.	Gangliosides	83-94	myelin basic protein	Homo sapiens	41-44
9972872-7	1999	Based on these results, we conclude that MBP(1-44) and MBP(152-167) associate with ganglioside GM1 and the bFGF receptor respectively to stimulate SC mitosis.	Gangliosides	83-94	myelin basic protein	Homo sapiens	55-58
9972872-7	1999	Based on these results, we conclude that MBP(1-44) and MBP(152-167) associate with ganglioside GM1 and the bFGF receptor respectively to stimulate SC mitosis.	G(M1) Ganglioside	95-98	myelin basic protein	Homo sapiens	41-44
9972872-7	1999	Based on these results, we conclude that MBP(1-44) and MBP(152-167) associate with ganglioside GM1 and the bFGF receptor respectively to stimulate SC mitosis.	G(M1) Ganglioside	95-98	myelin basic protein	Homo sapiens	55-58
10027703-2	1999	In vitro, MBP-associated arginine is deiminated to citrulline by the enzyme peptidylarginine deiminase (PAD).	Arginine	25-33	myelin basic protein	Homo sapiens	10-13
10027703-2	1999	In vitro, MBP-associated arginine is deiminated to citrulline by the enzyme peptidylarginine deiminase (PAD).	Citrulline	51-61	myelin basic protein	Homo sapiens	10-13
9892640-1	1999	Mannan-binding protein (MBP), a Ca2+-dependent mammalian lectin specific for mannose and N-acetylglucosamine, is an important serum component associated with innate immunity.	Mannose	77-84	myelin basic protein	Homo sapiens	0-22
9892640-1	1999	Mannan-binding protein (MBP), a Ca2+-dependent mammalian lectin specific for mannose and N-acetylglucosamine, is an important serum component associated with innate immunity.	Mannose	77-84	myelin basic protein	Homo sapiens	24-27
9892640-1	1999	Mannan-binding protein (MBP), a Ca2+-dependent mammalian lectin specific for mannose and N-acetylglucosamine, is an important serum component associated with innate immunity.	Acetylglucosamine	89-108	myelin basic protein	Homo sapiens	0-22
9892640-1	1999	Mannan-binding protein (MBP), a Ca2+-dependent mammalian lectin specific for mannose and N-acetylglucosamine, is an important serum component associated with innate immunity.	Acetylglucosamine	89-108	myelin basic protein	Homo sapiens	24-27
9892640-2	1999	MBP activates complement and functions as a direct opsonin on binding to mannooligosaccharide-bearing pathogens.	mannooligosaccharide	73-93	myelin basic protein	Homo sapiens	0-3
9892640-3	1999	We have found that MBP recognizes and binds specifically to oligosaccharide ligands expressed on the surfaces of a human colorectal carcinoma.	Oligosaccharides	60-75	myelin basic protein	Homo sapiens	19-22
10187830-5	1999	Reactivation of MBP-E1 denatured in 8 M urea was absolutely dependent on GroEL/GroES and Mg2+-ATP, and exhibited strikingly slow kinetics with a rate constant of 376 M-1 s-1, analogous to denatured untagged E1.	Urea	40-44	myelin basic protein	Homo sapiens	16-19
10187830-5	1999	Reactivation of MBP-E1 denatured in 8 M urea was absolutely dependent on GroEL/GroES and Mg2+-ATP, and exhibited strikingly slow kinetics with a rate constant of 376 M-1 s-1, analogous to denatured untagged E1.	magnesium ion	89-93	myelin basic protein	Homo sapiens	16-19
10187830-5	1999	Reactivation of MBP-E1 denatured in 8 M urea was absolutely dependent on GroEL/GroES and Mg2+-ATP, and exhibited strikingly slow kinetics with a rate constant of 376 M-1 s-1, analogous to denatured untagged E1.	Adenosine Triphosphate	94-97	myelin basic protein	Homo sapiens	16-19
10191299-2	1999	Microsequence analysis of the purified reduced MBP 200R characterized tryptic peptides of MBP 200R.	Peptides	78-86	myelin basic protein	Homo sapiens	47-50
10191299-2	1999	Microsequence analysis of the purified reduced MBP 200R characterized tryptic peptides of MBP 200R.	Peptides	78-86	myelin basic protein	Homo sapiens	90-93
10066452-2	1999	MBP activates the complement pathway through its interaction with mannose-rich carbohydrates on various microorganisms and a common opsonic defect has been shown to be associated with a low serum concentration of MBP.	Mannose	66-73	myelin basic protein	Homo sapiens	0-3
10066452-2	1999	MBP activates the complement pathway through its interaction with mannose-rich carbohydrates on various microorganisms and a common opsonic defect has been shown to be associated with a low serum concentration of MBP.	rich carbohydrates	74-92	myelin basic protein	Homo sapiens	0-3
10203578-5	1999	An oligodendrocyte-specific myelin basic protein (MBP) gene promoter controls the reversed tet-inducible transactivator.	Tetracycline	91-94	myelin basic protein	Homo sapiens	28-48
10203578-5	1999	An oligodendrocyte-specific myelin basic protein (MBP) gene promoter controls the reversed tet-inducible transactivator.	Tetracycline	91-94	myelin basic protein	Homo sapiens	50-53
10224325-8	1999	The DNA fragments generated by diepoxides were initially large, their concentration decreasing monotonously from 7 Mbp to less than 1 Mbp and were converted to smaller fragments by 72 h in the course of cell death.	diepoxides	31-41	myelin basic protein	Homo sapiens	134-137
10224325-9	1999	In contrast, DNA fragments induced by formaldehyde peaked below 1 Mbp, implicating activation of DNA-degrading enzymes.	Formaldehyde	38-50	myelin basic protein	Homo sapiens	66-69
10025732-4	1999	Enzyme immunoassay using biotinyl-MBP-rp17 indirectly immobilized onto polystyrene beads, which had been coated sequentially with biotinyl-bovine serum albumin and streptavidin, was approximately 1,000-fold more sensitive than that using directly immobilized rp17 antigen and Western blotting for p17 band.	Polystyrenes	71-82	myelin basic protein	Homo sapiens	34-37
21080259-3	1999	The utility of the method is demonstrated on a complex of methyl protonated, highly deuterated maltose binding protein (MBP, 370 residues) and beta- cyclodextrin.	betadex	143-161	myelin basic protein	Homo sapiens	120-123
10071937-6	1999	The fusion between MBP and cathepsin D had increased hydrophobic surface exposure compared to the two unfused partners, as determined by bis-ANS binding.	5,5'-bis(8-(phenylamino)-1-naphthalenesulfonate)	137-144	myelin basic protein	Homo sapiens	19-22
9886404-4	1999	In the crystal structure of the HLA-DR2/MBP peptide complex, P5 lysine is a prominent, solvent-exposed residue in the center of the DR2/MBP peptide surface.	Lysine	64-70	myelin basic protein	Homo sapiens	40-43
9886404-4	1999	In the crystal structure of the HLA-DR2/MBP peptide complex, P5 lysine is a prominent, solvent-exposed residue in the center of the DR2/MBP peptide surface.	Lysine	64-70	myelin basic protein	Homo sapiens	136-139
9808760-3	1998	Myelin basic protein bound to all three conformational forms of alpha2-macroglobulin studied, i.e., native alpha2-macroglobulin, methylamine-treated alpha2-macroglobulin, and chymotrypsin-treated alpha2-macroglobulin.	methylamine	129-140	myelin basic protein	Homo sapiens	0-20
9876226-8	1998	Topical steroid treatment was accompanied by a decrease in both the CD3+ and major basic protein (MBP+) cells expressing GM-CSF mRNA (p = 0.01) with a corresponding proportionate increase in the % of macrophages expressing GM-CSF.	Steroids	8-15	myelin basic protein	Homo sapiens	98-101
9832639-1	1998	Mannan binding protein (MBP) is a C-type lectin and has a high affinity to mannose and N-acetyl glucosamine.	Mannose	75-82	myelin basic protein	Homo sapiens	0-22
9832639-1	1998	Mannan binding protein (MBP) is a C-type lectin and has a high affinity to mannose and N-acetyl glucosamine.	Mannose	75-82	myelin basic protein	Homo sapiens	24-27
9832639-1	1998	Mannan binding protein (MBP) is a C-type lectin and has a high affinity to mannose and N-acetyl glucosamine.	Acetylglucosamine	87-107	myelin basic protein	Homo sapiens	0-22
9832639-1	1998	Mannan binding protein (MBP) is a C-type lectin and has a high affinity to mannose and N-acetyl glucosamine.	Acetylglucosamine	87-107	myelin basic protein	Homo sapiens	24-27
9832639-7	1998	In addition, MBP-positive cases showed marked mesangial cell proliferation, lower creatinine clearance (53.4 +/- 10.0 vs. 77.	Creatinine	82-92	myelin basic protein	Homo sapiens	13-16
9832639-10	1998	Since oligosaccharide chain alterations such as reduced sialic acid and galactose of IgA1 molecule have been reported in IgA nephropathy patients, MBP might bind to the IgA1 molecule via interaction between MBP and sugar chain.	Oligosaccharides	6-21	myelin basic protein	Homo sapiens	147-150
9832639-10	1998	Since oligosaccharide chain alterations such as reduced sialic acid and galactose of IgA1 molecule have been reported in IgA nephropathy patients, MBP might bind to the IgA1 molecule via interaction between MBP and sugar chain.	Oligosaccharides	6-21	myelin basic protein	Homo sapiens	207-210
9832639-10	1998	Since oligosaccharide chain alterations such as reduced sialic acid and galactose of IgA1 molecule have been reported in IgA nephropathy patients, MBP might bind to the IgA1 molecule via interaction between MBP and sugar chain.	N-Acetylneuraminic Acid	56-67	myelin basic protein	Homo sapiens	147-150
9832639-10	1998	Since oligosaccharide chain alterations such as reduced sialic acid and galactose of IgA1 molecule have been reported in IgA nephropathy patients, MBP might bind to the IgA1 molecule via interaction between MBP and sugar chain.	Galactose	72-81	myelin basic protein	Homo sapiens	147-150
9832639-10	1998	Since oligosaccharide chain alterations such as reduced sialic acid and galactose of IgA1 molecule have been reported in IgA nephropathy patients, MBP might bind to the IgA1 molecule via interaction between MBP and sugar chain.	Sugars	215-220	myelin basic protein	Homo sapiens	147-150
9808760-4	1998	Zinc chloride (1 mM) or 1 mM iodoacetamide partly blocked the complex formation between myelin basic protein and alpha2-macroglobulin, while 1 mM magnesium chloride, 1 mM calcium chloride, or 1 mM EDTA had no effect on binding.	zinc chloride	0-13	myelin basic protein	Homo sapiens	88-108
9808760-4	1998	Zinc chloride (1 mM) or 1 mM iodoacetamide partly blocked the complex formation between myelin basic protein and alpha2-macroglobulin, while 1 mM magnesium chloride, 1 mM calcium chloride, or 1 mM EDTA had no effect on binding.	Iodoacetamide	29-42	myelin basic protein	Homo sapiens	88-108
9824513-9	1998	Assessment of the activities of the alpha and beta isoforms of conventional protein kinase C (PKC), as determined by MonoQ column fractionated calcium and lipid activatible phosphotransferase activity towards myelin basic protein (MBP) revealed an additive effect of using LPS, IFN-gamma and GM-CSF, which was even greater than that demonstrated for phorbol myristate acetate (PMA).	Calcium	143-150	myelin basic protein	Homo sapiens	209-229
9846830-1	1998	The synthetic amino acid copolymer, copolymer 1 (Cop 1) induces T suppressor (Ts) lines/clones, which are confined to the Th2 pathway, cross react with myelin basic protein (MBP), but not with other myelin antigens on the level of Th2 cytokine secretion.	amino acid copolymer	14-34	myelin basic protein	Homo sapiens	152-172
9846830-1	1998	The synthetic amino acid copolymer, copolymer 1 (Cop 1) induces T suppressor (Ts) lines/clones, which are confined to the Th2 pathway, cross react with myelin basic protein (MBP), but not with other myelin antigens on the level of Th2 cytokine secretion.	amino acid copolymer	14-34	myelin basic protein	Homo sapiens	174-177
9846830-1	1998	The synthetic amino acid copolymer, copolymer 1 (Cop 1) induces T suppressor (Ts) lines/clones, which are confined to the Th2 pathway, cross react with myelin basic protein (MBP), but not with other myelin antigens on the level of Th2 cytokine secretion.	copolymer	25-34	myelin basic protein	Homo sapiens	152-172
9846830-1	1998	The synthetic amino acid copolymer, copolymer 1 (Cop 1) induces T suppressor (Ts) lines/clones, which are confined to the Th2 pathway, cross react with myelin basic protein (MBP), but not with other myelin antigens on the level of Th2 cytokine secretion.	copolymer	25-34	myelin basic protein	Homo sapiens	174-177
9809995-1	1998	A novel anticancer drug, cytotrienin A, isolated from Streptomyces sp., induces apoptosis (or programmed cell death) in human promyelocytic leukemia HL-60 cells within 4 h. To elucidate the mechanism of this process, we performed an in-gel kinase assay using myelin basic protein (MBP) as a substrate and found the activation of kinase with an apparent molecular mass of 36 kDa (p36 MBP kinase).	cytotrienin A	25-38	myelin basic protein	Homo sapiens	259-279
9809995-1	1998	A novel anticancer drug, cytotrienin A, isolated from Streptomyces sp., induces apoptosis (or programmed cell death) in human promyelocytic leukemia HL-60 cells within 4 h. To elucidate the mechanism of this process, we performed an in-gel kinase assay using myelin basic protein (MBP) as a substrate and found the activation of kinase with an apparent molecular mass of 36 kDa (p36 MBP kinase).	cytotrienin A	25-38	myelin basic protein	Homo sapiens	281-284
9809995-1	1998	A novel anticancer drug, cytotrienin A, isolated from Streptomyces sp., induces apoptosis (or programmed cell death) in human promyelocytic leukemia HL-60 cells within 4 h. To elucidate the mechanism of this process, we performed an in-gel kinase assay using myelin basic protein (MBP) as a substrate and found the activation of kinase with an apparent molecular mass of 36 kDa (p36 MBP kinase).	cytotrienin A	25-38	myelin basic protein	Homo sapiens	383-386
9809995-2	1998	The dose of cytotrienin A required to activate p36 MBP kinase was consistent with that required to induce apoptotic DNA fragmentation in HL-60 cells.	cytotrienin A	12-25	myelin basic protein	Homo sapiens	51-54
9809995-5	1998	In addition, the p36 MBP kinase activation and apoptotic DNA fragmentation were inhibited by antioxidants such as N-acetylcysteine and reduced-form glutathione.	Acetylcysteine	114-130	myelin basic protein	Homo sapiens	21-24
9809995-5	1998	In addition, the p36 MBP kinase activation and apoptotic DNA fragmentation were inhibited by antioxidants such as N-acetylcysteine and reduced-form glutathione.	Glutathione	148-159	myelin basic protein	Homo sapiens	21-24
9809995-6	1998	The p36 MBP kinase activation was also observed during hydrogen peroxide (H2O2) and okadaic acid-induced apoptosis.	Hydrogen Peroxide	55-72	myelin basic protein	Homo sapiens	8-11
9809995-6	1998	The p36 MBP kinase activation was also observed during hydrogen peroxide (H2O2) and okadaic acid-induced apoptosis.	Hydrogen Peroxide	74-78	myelin basic protein	Homo sapiens	8-11
9809995-6	1998	The p36 MBP kinase activation was also observed during hydrogen peroxide (H2O2) and okadaic acid-induced apoptosis.	Okadaic Acid	84-96	myelin basic protein	Homo sapiens	8-11
9809995-8	1998	Surprisingly, Z-Asp-CH2-DCB inhibited the activation of p36 MBP kinase induced by cytotrienin A or H2O2, but did not inhibit the activation of JNK/stress-activated protein kinase and p38 MAPK.	benzyloxycarbonyl-Asp-CH2OC(O)-2,6-dichlorobenzene	14-27	myelin basic protein	Homo sapiens	60-63
9809995-8	1998	Surprisingly, Z-Asp-CH2-DCB inhibited the activation of p36 MBP kinase induced by cytotrienin A or H2O2, but did not inhibit the activation of JNK/stress-activated protein kinase and p38 MAPK.	cytotrienin A	82-95	myelin basic protein	Homo sapiens	60-63
9809995-8	1998	Surprisingly, Z-Asp-CH2-DCB inhibited the activation of p36 MBP kinase induced by cytotrienin A or H2O2, but did not inhibit the activation of JNK/stress-activated protein kinase and p38 MAPK.	Hydrogen Peroxide	99-103	myelin basic protein	Homo sapiens	60-63
9809995-9	1998	Taken together, these results indicate that p36 MBP kinase activation is downstream of the activation of Z-Asp-CH2-DCB-sensitive caspases, and reactive oxygen species could be included in the apoptotic events.	benzyloxycarbonyl-asparagine	105-110	myelin basic protein	Homo sapiens	48-51
9809995-9	1998	Taken together, these results indicate that p36 MBP kinase activation is downstream of the activation of Z-Asp-CH2-DCB-sensitive caspases, and reactive oxygen species could be included in the apoptotic events.	dcb	115-118	myelin basic protein	Homo sapiens	48-51
9809995-9	1998	Taken together, these results indicate that p36 MBP kinase activation is downstream of the activation of Z-Asp-CH2-DCB-sensitive caspases, and reactive oxygen species could be included in the apoptotic events.	Reactive Oxygen Species	143-166	myelin basic protein	Homo sapiens	48-51
9863582-1	1998	This study set out to investigate whether plasma mannose-binding protein (MBP) deficiency caused by mutations in the MBP gene associates with pyogenic or opportunistic infections in HIV-infected patients.	Mannose	49-56	myelin basic protein	Homo sapiens	74-77
9877027-5	1998	Increased expression of p21CiP1, phosphorylation of Bcl-2, and activation of p33 MBP kinase may play part of the key mechanism for FR-induced apoptosis.	romidepsin	131-133	myelin basic protein	Homo sapiens	81-84
9782128-4	1998	A distinguishing feature of the HLA-DR2 peptide binding site is a large, primarily hydrophobic P4 pocket that accommodates a phenylalanine of the MBP peptide.	Phenylalanine	125-138	myelin basic protein	Homo sapiens	146-149
11477890-6	1998	In REM sleep, the changes in MBP showed significantly correlation with the changes in oxygen saturation during apnea (r = 0.598, P < 0.05).	Oxygen	86-92	myelin basic protein	Homo sapiens	29-32
9751750-8	1998	The purified HLA-DR2/MBP peptide complex readily crystallized by the hanging drop method in 15-18% polyethylene glycol 6000/100 mM glycine, pH 3.5.	Polyethylene Glycols	99-118	myelin basic protein	Homo sapiens	21-24
9751750-8	1998	The purified HLA-DR2/MBP peptide complex readily crystallized by the hanging drop method in 15-18% polyethylene glycol 6000/100 mM glycine, pH 3.5.	Glycine	131-138	myelin basic protein	Homo sapiens	21-24
9739983-3	1998	We also showed that cytokine production by MBP-stimulated monocytes was abrogated by incubation with Dexamethasone.	Dexamethasone	101-114	myelin basic protein	Homo sapiens	43-46
9793811-10	1998	Three minutes after SA significant decrease in the following parameters was observed: SBP in group PL compared with the other three groups (p = 0.004), DBP in group PL vs. groups C5 and C2.5 (p = 0.002), and MBP in group PL vs. groups C5 and C2.5 (p = 0.003).	sa	20-22	myelin basic protein	Homo sapiens	208-211
9724006-4	1998	In parallel, ELISPOT assay to detect MBP- and PHA-reactive IFN-gamma secreting blood MNC+/-Linomide was used.	roquinimex	91-99	myelin basic protein	Homo sapiens	37-40
9698606-4	1998	Assays of immune-complex kinase activity revealed that exposure of PASMC to H2O2 stimulated myelin basic protein (MBP) phosphorylation in a concentration- and time-dependent manner.	pasmc	67-72	myelin basic protein	Homo sapiens	92-112
9698606-4	1998	Assays of immune-complex kinase activity revealed that exposure of PASMC to H2O2 stimulated myelin basic protein (MBP) phosphorylation in a concentration- and time-dependent manner.	pasmc	67-72	myelin basic protein	Homo sapiens	114-117
9698606-4	1998	Assays of immune-complex kinase activity revealed that exposure of PASMC to H2O2 stimulated myelin basic protein (MBP) phosphorylation in a concentration- and time-dependent manner.	Hydrogen Peroxide	76-80	myelin basic protein	Homo sapiens	92-112
9698606-4	1998	Assays of immune-complex kinase activity revealed that exposure of PASMC to H2O2 stimulated myelin basic protein (MBP) phosphorylation in a concentration- and time-dependent manner.	Hydrogen Peroxide	76-80	myelin basic protein	Homo sapiens	114-117
9724006-5	1998	RESULTS: Here we report that Linomide, a synthetic immunomodulator, at concentrations effective in vivo reduces the number of MBP-reactive TNF-alpha and increases MBP-reactive IL-10 and TGF-beta mRNA expressing MNC from MS patients" blood when analysed in vitro.	roquinimex	29-37	myelin basic protein	Homo sapiens	163-166
9724006-6	1998	Compared to dexamethasone, Linomide up-regulated levels of blood MNC expressing mRNA of TGF-beta after culture in presence of MBP.	roquinimex	27-35	myelin basic protein	Homo sapiens	126-129
9724006-5	1998	RESULTS: Here we report that Linomide, a synthetic immunomodulator, at concentrations effective in vivo reduces the number of MBP-reactive TNF-alpha and increases MBP-reactive IL-10 and TGF-beta mRNA expressing MNC from MS patients" blood when analysed in vitro.	roquinimex	29-37	myelin basic protein	Homo sapiens	126-129
9720214-1	1998	Mannan-binding protein (MBP) is a calcium-dependent mammalian serum lectin important in first-line host defense.	Calcium	34-41	myelin basic protein	Homo sapiens	0-22
9716101-1	1998	Mannan-binding lectin (MBL, previously named mannan-binding protein, MBP) is a serum collectin, which activates complement upon binding to microbial carbohydrates.	Carbohydrates	149-162	myelin basic protein	Homo sapiens	69-72
9667590-2	1998	In vitro studies with myelin basic protein (MBP)-specific T-cell lines revealed a synergistic suppressive effect of IFN-beta1b and the phosphodiesterase inhibitor pentoxifylline (PTX) on proliferation and the production of tumor necrosis factor-alpha (TNF-alpha), lymphotoxin (LT), and interferon-gamma (IFN-gamma).	Pentoxifylline	163-177	myelin basic protein	Homo sapiens	22-42
9667590-2	1998	In vitro studies with myelin basic protein (MBP)-specific T-cell lines revealed a synergistic suppressive effect of IFN-beta1b and the phosphodiesterase inhibitor pentoxifylline (PTX) on proliferation and the production of tumor necrosis factor-alpha (TNF-alpha), lymphotoxin (LT), and interferon-gamma (IFN-gamma).	Pentoxifylline	163-177	myelin basic protein	Homo sapiens	44-47
9667590-2	1998	In vitro studies with myelin basic protein (MBP)-specific T-cell lines revealed a synergistic suppressive effect of IFN-beta1b and the phosphodiesterase inhibitor pentoxifylline (PTX) on proliferation and the production of tumor necrosis factor-alpha (TNF-alpha), lymphotoxin (LT), and interferon-gamma (IFN-gamma).	Pentoxifylline	179-182	myelin basic protein	Homo sapiens	22-42
9667590-2	1998	In vitro studies with myelin basic protein (MBP)-specific T-cell lines revealed a synergistic suppressive effect of IFN-beta1b and the phosphodiesterase inhibitor pentoxifylline (PTX) on proliferation and the production of tumor necrosis factor-alpha (TNF-alpha), lymphotoxin (LT), and interferon-gamma (IFN-gamma).	Pentoxifylline	179-182	myelin basic protein	Homo sapiens	44-47
9704165-1	1998	inhibitor rolipram in vitro reduces the numbers of MBP-reactive IFN-gamma and TNF-alpha mRNA expressing blood mononuclear cells in patients with multiple sclerosis.	Rolipram	10-18	myelin basic protein	Homo sapiens	51-54
9704165-9	1998	Rolipram reduced the numbers of MBP-reactive IFN-gamma- and TNF-alpha mRNA-expressing blood MNC in MS, and numbers of AChR-reactive IFN-gamma-, TNF-alpha-, and LT mRNA-positive cells in MG.	Rolipram	0-8	myelin basic protein	Homo sapiens	32-35
9720214-1	1998	Mannan-binding protein (MBP) is a calcium-dependent mammalian serum lectin important in first-line host defense.	Calcium	34-41	myelin basic protein	Homo sapiens	24-27
9720214-2	1998	MBP belongs to the collectin family, which is characterized by an NH2-terminal cysteine-rich domain, a collagen-like domain, a neck domain, and a carbohydrate recognition domain (CRD).	Cysteine	79-87	myelin basic protein	Homo sapiens	0-3
9720214-2	1998	MBP belongs to the collectin family, which is characterized by an NH2-terminal cysteine-rich domain, a collagen-like domain, a neck domain, and a carbohydrate recognition domain (CRD).	Carbohydrates	146-158	myelin basic protein	Homo sapiens	0-3
9720214-4	1998	The truncated MBP was capable of forming trimers by association of the neck domain and could bind sugar with a specificity similar to that of the native form.	Sugars	98-103	myelin basic protein	Homo sapiens	14-17
9633939-2	1998	One potential mechanism is via a unique receptor pathway we previously identified in human blood and THP-1 monocytes and macrophages for the lipoprotein lipase (LpL)- and apolipoprotein (apo) E-independent, high-affinity, specific binding of plasma chylomicrons and hypertriglyceridemic VLDL (HTG-VLDL) to cell-surface membrane-binding proteins (MBP 200, 235; apparent Mr 200, 235 kD on SDS-PAGE) that leads to lipid accumulation in vitro.	Sodium Dodecyl Sulfate	387-390	myelin basic protein	Homo sapiens	346-349
9678250-4	1998	MBP-PGA and the PGA segment obtained by factor Xa digestion (designated as r-PGA) possessed proteolytic activities equivalent to native PGA purified from gastric tissue (t-PGA).	Prostaglandins A	4-7	myelin basic protein	Homo sapiens	0-3
9623609-6	1998	The increase in tyrosine phosphorylation of these proteins during capacitation was accompanied by increased kinase activity, as determined by the ability of ERK-1 and ERK-2 to phosphorylate the substrate myelin basic protein.	Tyrosine	16-24	myelin basic protein	Homo sapiens	204-224
9678250-4	1998	MBP-PGA and the PGA segment obtained by factor Xa digestion (designated as r-PGA) possessed proteolytic activities equivalent to native PGA purified from gastric tissue (t-PGA).	r-pga	75-80	myelin basic protein	Homo sapiens	0-3
9678250-4	1998	MBP-PGA and the PGA segment obtained by factor Xa digestion (designated as r-PGA) possessed proteolytic activities equivalent to native PGA purified from gastric tissue (t-PGA).	t-pga	170-175	myelin basic protein	Homo sapiens	0-3
9758081-1	1998	In studies of the effects of salt intake on blood pressure (SBP, MBP, DBP), influences on heart rate (HR) are usually neglected even though the longterm load on both left ventricle (LV) and systemic arteries (SA) is better related to the product of HR x SBP (or MBP) than to pressure alone.	Salts	29-33	myelin basic protein	Homo sapiens	65-68
9762659-5	1998	From several relevant studies about CSF MBP in RR MS the following relations can be concluded: CSF MBP levels in active MS patients are frequently increased (45-100%), remain increased until 5 to 6 weeks after onset symptoms and are higher in polysymptomatic exacerbations and correlate with number of gadolinium-enhanced (Gd) lesions on MRI, severity of relapses, EDSS score and CSF intrathecal IgM synthesis.	Gadolinium	302-312	myelin basic protein	Homo sapiens	99-102
9762659-6	1998	After an intravenous methylprednisolone treatment the increased CSF MBP levels return to normal values and reduction in CSF MBP is related to reduction in EDSS score, number of Gd lesions and CSF intrathecal IgM synthesis.	Methylprednisolone	21-39	myelin basic protein	Homo sapiens	68-71
9762659-6	1998	After an intravenous methylprednisolone treatment the increased CSF MBP levels return to normal values and reduction in CSF MBP is related to reduction in EDSS score, number of Gd lesions and CSF intrathecal IgM synthesis.	Methylprednisolone	21-39	myelin basic protein	Homo sapiens	124-127
9490653-3	1998	SP-A belongs to the family of collagenous C-type lectins along with mannose binding protein (MBP) and SP-D, both of which have also been mapped to the long arm of chromosome 10.	Mannose	68-75	myelin basic protein	Homo sapiens	93-96
9529088-7	1998	Hapten inhibition assays with monosaccharides and defined oligosaccharides showed that the inhibitory effects of MBP were abrogated by mannose or high-mannose type oligomannose-oligosaccharide.	Monosaccharides	30-45	myelin basic protein	Homo sapiens	113-116
9529088-7	1998	Hapten inhibition assays with monosaccharides and defined oligosaccharides showed that the inhibitory effects of MBP were abrogated by mannose or high-mannose type oligomannose-oligosaccharide.	Oligosaccharides	58-74	myelin basic protein	Homo sapiens	113-116
9529088-7	1998	Hapten inhibition assays with monosaccharides and defined oligosaccharides showed that the inhibitory effects of MBP were abrogated by mannose or high-mannose type oligomannose-oligosaccharide.	Mannose	135-142	myelin basic protein	Homo sapiens	113-116
9529088-7	1998	Hapten inhibition assays with monosaccharides and defined oligosaccharides showed that the inhibitory effects of MBP were abrogated by mannose or high-mannose type oligomannose-oligosaccharide.	high-mannose	146-158	myelin basic protein	Homo sapiens	113-116
9529088-7	1998	Hapten inhibition assays with monosaccharides and defined oligosaccharides showed that the inhibitory effects of MBP were abrogated by mannose or high-mannose type oligomannose-oligosaccharide.	oligomannose-oligosaccharide	164-192	myelin basic protein	Homo sapiens	113-116
9529088-8	1998	The latter carbohydrate is the ligand of the 40-kDa glycoprotein of C. trachomatis L2, which is known to mediate attachment, suggesting that the MBP binds to high mannose moieties on the surface of chlamydial organisms.	Carbohydrates	11-23	myelin basic protein	Homo sapiens	145-148
9529088-8	1998	The latter carbohydrate is the ligand of the 40-kDa glycoprotein of C. trachomatis L2, which is known to mediate attachment, suggesting that the MBP binds to high mannose moieties on the surface of chlamydial organisms.	Mannose	163-170	myelin basic protein	Homo sapiens	145-148
9482255-8	1998	In contrast to antisense-treated cells, MBP synthesis was essentially blocked in quercetin-treated cells even though levels of HSP25 and GRP78 increased.	Quercetin	81-90	myelin basic protein	Homo sapiens	40-43
9755813-2	1998	In these cells, it has been shown that ATP stimulates myelin basic protein (MBP) kinase activity which is believed to represent the Erk family of MAP kinases.	Adenosine Triphosphate	39-42	myelin basic protein	Homo sapiens	54-74
9602861-7	1998	In line with a genotoxic mechanism and absence of additional cytotoxic effects, the DNA fragments generated by gamma-irradiation as well as by etoposide and melphalan displayed a distribution between 1 and 4 Mbp with a peak around 2 Mbp.	Etoposide	143-152	myelin basic protein	Homo sapiens	208-211
9602861-7	1998	In line with a genotoxic mechanism and absence of additional cytotoxic effects, the DNA fragments generated by gamma-irradiation as well as by etoposide and melphalan displayed a distribution between 1 and 4 Mbp with a peak around 2 Mbp.	Etoposide	143-152	myelin basic protein	Homo sapiens	233-236
9602861-7	1998	In line with a genotoxic mechanism and absence of additional cytotoxic effects, the DNA fragments generated by gamma-irradiation as well as by etoposide and melphalan displayed a distribution between 1 and 4 Mbp with a peak around 2 Mbp.	Melphalan	157-166	myelin basic protein	Homo sapiens	208-211
9602861-7	1998	In line with a genotoxic mechanism and absence of additional cytotoxic effects, the DNA fragments generated by gamma-irradiation as well as by etoposide and melphalan displayed a distribution between 1 and 4 Mbp with a peak around 2 Mbp.	Melphalan	157-166	myelin basic protein	Homo sapiens	233-236
9602861-8	1998	In contrast, DNA fragments induced by Triton X-100 and KCN peaked below 0.5 Mbp, implicating activation of DNA-degrading enzymes.	Octoxynol	38-50	myelin basic protein	Homo sapiens	76-79
9602861-8	1998	In contrast, DNA fragments induced by Triton X-100 and KCN peaked below 0.5 Mbp, implicating activation of DNA-degrading enzymes.	Potassium Cyanide	55-58	myelin basic protein	Homo sapiens	76-79
9438554-0	1998	Active oxygen-mediated chromosomal 1-2 Mbp giant DNA fragmentation into internucleosomal DNA fragmentation in apoptosis of glioma cells induced by glutamate.	Oxygen	7-13	myelin basic protein	Homo sapiens	39-42
9438554-0	1998	Active oxygen-mediated chromosomal 1-2 Mbp giant DNA fragmentation into internucleosomal DNA fragmentation in apoptosis of glioma cells induced by glutamate.	Glutamic Acid	147-156	myelin basic protein	Homo sapiens	39-42
9438554-8	1998	These findings suggest that glutamate induces GSH depletion, and consequently, apoptosis through endogenously produced active oxygen species in C6 glioma cells and that the apoptosis is accompanied by 1-2 Mbp giant DNA fragmentation prior to the internucleosomal DNA fragmentation.	Glutamic Acid	28-37	myelin basic protein	Homo sapiens	205-208
9526851-6	1998	This difference was almost entirely due to the presence of high numbers of LB-MBP-specific TCL in MS patients which did not cross-react with LF-MBP and were not present in healthy subjects.	Triclosan	91-94	myelin basic protein	Homo sapiens	78-81
9482678-0	1998	The myelin basic protein gene in multiple sclerosis: identification of discrete alleles of a 1.3 kb tetranucleotide repeat sequence.	tetranucleotide	100-115	myelin basic protein	Homo sapiens	4-24
9482678-2	1998	Linkage and association with certain alleles of a 1.2 kb tetranucleotide repeat region 5" to the MBP gene with MS have been reported in Finnish patients, and an association has been reported from Denmark.	tetranucleotide	57-72	myelin basic protein	Homo sapiens	97-100
9755813-2	1998	In these cells, it has been shown that ATP stimulates myelin basic protein (MBP) kinase activity which is believed to represent the Erk family of MAP kinases.	Adenosine Triphosphate	39-42	myelin basic protein	Homo sapiens	76-79
9755813-3	1998	Indeed, we show that ATP activates simultaneously MBP kinase activity and phosphotyrosine incorporation in p42 Erk2 and p44 Erk1.	Adenosine Triphosphate	21-24	myelin basic protein	Homo sapiens	50-53
9406533-3	1997	The insoluble perchlorate salt of the poly(benzyl viologen) dication was used to immobilize MBP-Nir onto an electrode previously modified with an electropolymerized film of PPB.	perchlorate salt	14-30	myelin basic protein	Homo sapiens	92-95
9498625-8	1998	Mono Q fractionation of hepatocyte extracts resolved a single myelin basic protein (MBP) kinase peak from extracts of EGF-treated cells (peak 1, eluting at 200 mmol/l NaCl) and two peaks from insulin-treated cells (peak 1 eluting at 200 mmol/l NaCl and peak 2 eluting at 400 mmol/l NaCl).	Mono Q	0-6	myelin basic protein	Homo sapiens	62-82
9498625-8	1998	Mono Q fractionation of hepatocyte extracts resolved a single myelin basic protein (MBP) kinase peak from extracts of EGF-treated cells (peak 1, eluting at 200 mmol/l NaCl) and two peaks from insulin-treated cells (peak 1 eluting at 200 mmol/l NaCl and peak 2 eluting at 400 mmol/l NaCl).	Mono Q	0-6	myelin basic protein	Homo sapiens	84-87
9498625-8	1998	Mono Q fractionation of hepatocyte extracts resolved a single myelin basic protein (MBP) kinase peak from extracts of EGF-treated cells (peak 1, eluting at 200 mmol/l NaCl) and two peaks from insulin-treated cells (peak 1 eluting at 200 mmol/l NaCl and peak 2 eluting at 400 mmol/l NaCl).	Sodium Chloride	167-171	myelin basic protein	Homo sapiens	84-87
9521617-4	1998	In both data-sets we found association between MS and alleles in the 1.27 kilobase (kb) range at a tetranucleotide repeat element (TGGA)n which is located 1 kb upstream of the MBP exon 1.	tetranucleotide	99-114	myelin basic protein	Homo sapiens	176-179
9752719-6	1998	A second methyltransferase activity that symmetrically dimethylates an arginine residue in myelin basic protein, a major component of the axon sheath, has also been characterized.	Arginine	71-79	myelin basic protein	Homo sapiens	91-111
9406533-3	1997	The insoluble perchlorate salt of the poly(benzyl viologen) dication was used to immobilize MBP-Nir onto an electrode previously modified with an electropolymerized film of PPB.	poly(benzyl viologen)	38-59	myelin basic protein	Homo sapiens	92-95
9406533-4	1997	The electropolymerized film of PPB on the GCE is redox active and exhibits special electron-transfer properties toward the MBP-Nir layer but not toward Nir (Nir without MBP fusion attached), suggesting an intimate interaction between the PPB film and the MBP-Nir layer.	PPB	31-34	myelin basic protein	Homo sapiens	123-126
9406533-4	1997	The electropolymerized film of PPB on the GCE is redox active and exhibits special electron-transfer properties toward the MBP-Nir layer but not toward Nir (Nir without MBP fusion attached), suggesting an intimate interaction between the PPB film and the MBP-Nir layer.	PPB	31-34	myelin basic protein	Homo sapiens	169-172
9406533-4	1997	The electropolymerized film of PPB on the GCE is redox active and exhibits special electron-transfer properties toward the MBP-Nir layer but not toward Nir (Nir without MBP fusion attached), suggesting an intimate interaction between the PPB film and the MBP-Nir layer.	PPB	31-34	myelin basic protein	Homo sapiens	169-172
9354646-1	1997	Rat liver cytosolic NADP+-specific isocitrate dehydrogenase (IDP2) was expressed in bacteria as a fusion protein with maltose binding protein (MBP).	NADP	20-24	myelin basic protein	Homo sapiens	118-141
9395124-0	1997	Tolerance induction to myelin basic protein by intravenous synthetic peptides containing epitope P85 VVHFFKNIVTP96 in chronic progressive multiple sclerosis.	Peptides	69-77	myelin basic protein	Homo sapiens	23-43
9640845-8	1997	These substances were specifically bound to MBP, and once bound, the MBP-MASP complexes were then able to consume C4.	imciromab pentetate	114-116	myelin basic protein	Homo sapiens	44-47
9640845-8	1997	These substances were specifically bound to MBP, and once bound, the MBP-MASP complexes were then able to consume C4.	imciromab pentetate	114-116	myelin basic protein	Homo sapiens	69-72
9640845-9	1997	CONCLUSION: MBP binds to immune complexes consisting of IgG and IgM-RF, and probably recognizes either the mannose moiety of IgM-RF or the N-acetyl-glucosamine of agalactosyl IgG.	Mannose	107-114	myelin basic protein	Homo sapiens	12-15
9640845-9	1997	CONCLUSION: MBP binds to immune complexes consisting of IgG and IgM-RF, and probably recognizes either the mannose moiety of IgM-RF or the N-acetyl-glucosamine of agalactosyl IgG.	Acetylglucosamine	139-159	myelin basic protein	Homo sapiens	12-15
9369943-5	1997	Under certain conditions, PD 098059 can completely block the PMA-induced activation of the p42ERK as monitored by immunoprecipitation kinase assay by using the substrate myelin basic protein.	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	26-35	myelin basic protein	Homo sapiens	170-190
9369943-5	1997	Under certain conditions, PD 098059 can completely block the PMA-induced activation of the p42ERK as monitored by immunoprecipitation kinase assay by using the substrate myelin basic protein.	Tetradecanoylphorbol Acetate	61-64	myelin basic protein	Homo sapiens	170-190
9374740-7	1997	Compared with SP release under control conditions (2.37 +/- 0.34%), major basic protein (MBP) increased release in a concentration-related fashion (e.g., 3 microM MBP: 6.23 +/- 0.67%, P = 0.006 vs. control), whereas neither eosinophil cationic protein (3 microM), eosinophil-derived neurotoxin (3 microM), leukotriene D4 (500 nM), platelet-activating factor (100 nM), nor H2O2 (100 microM) affected SP release.	Leukotriene D4	306-320	myelin basic protein	Homo sapiens	89-92
9374740-7	1997	Compared with SP release under control conditions (2.37 +/- 0.34%), major basic protein (MBP) increased release in a concentration-related fashion (e.g., 3 microM MBP: 6.23 +/- 0.67%, P = 0.006 vs. control), whereas neither eosinophil cationic protein (3 microM), eosinophil-derived neurotoxin (3 microM), leukotriene D4 (500 nM), platelet-activating factor (100 nM), nor H2O2 (100 microM) affected SP release.	Hydrogen Peroxide	372-376	myelin basic protein	Homo sapiens	89-92
9384464-7	1997	A significant decrease was observed in MBP (MBP:PGI2: -1.7%; -1.9% and -5.6% vs Plac: -0.4%; -1.6% and +2.1%, P < or = 0.01 for 8 ng kg(-1) min(-1)).	Epoprostenol	48-52	myelin basic protein	Homo sapiens	39-42
9384464-7	1997	A significant decrease was observed in MBP (MBP:PGI2: -1.7%; -1.9% and -5.6% vs Plac: -0.4%; -1.6% and +2.1%, P < or = 0.01 for 8 ng kg(-1) min(-1)).	Epoprostenol	48-52	myelin basic protein	Homo sapiens	44-47
9354646-1	1997	Rat liver cytosolic NADP+-specific isocitrate dehydrogenase (IDP2) was expressed in bacteria as a fusion protein with maltose binding protein (MBP).	NADP	20-24	myelin basic protein	Homo sapiens	143-146
9300722-9	1997	Removal of human mannose binding protein (hMBP) by preincubation of serum with a specific mAb abrogated TNF-alpha induction by MP2 and strongly inhibited its binding to PBMCs.	Mannose	17-24	myelin basic protein	Homo sapiens	42-46
9341140-3	1997	Gastrin and phorbol 12-myristate 13-acetate (PMA) treatment of AGS-B cells was found to increase the phosphorylation of tyrosine residues of extracellular signal-regulated kinases (ERKs) 1 and 2 and increase ERK activity as determined by the in vitro phosphorylation of myelin basic protein.	Tetradecanoylphorbol Acetate	12-43	myelin basic protein	Homo sapiens	270-290
9341140-3	1997	Gastrin and phorbol 12-myristate 13-acetate (PMA) treatment of AGS-B cells was found to increase the phosphorylation of tyrosine residues of extracellular signal-regulated kinases (ERKs) 1 and 2 and increase ERK activity as determined by the in vitro phosphorylation of myelin basic protein.	Tetradecanoylphorbol Acetate	45-48	myelin basic protein	Homo sapiens	270-290
9341140-3	1997	Gastrin and phorbol 12-myristate 13-acetate (PMA) treatment of AGS-B cells was found to increase the phosphorylation of tyrosine residues of extracellular signal-regulated kinases (ERKs) 1 and 2 and increase ERK activity as determined by the in vitro phosphorylation of myelin basic protein.	Tyrosine	120-128	myelin basic protein	Homo sapiens	270-290
9399586-7	1997	In addition, we showed that both S-MBP and L-MBP undergo hydroxylation of lysine and proline residues in collagen-like sequences, and that the hydroxylysine is glycosylated to form glucosylgalactosylhydroxylysine (GluGalHyl) and galactosylhydroxylysine (GalHyl).	Lysine	74-80	myelin basic protein	Homo sapiens	35-38
9399586-7	1997	In addition, we showed that both S-MBP and L-MBP undergo hydroxylation of lysine and proline residues in collagen-like sequences, and that the hydroxylysine is glycosylated to form glucosylgalactosylhydroxylysine (GluGalHyl) and galactosylhydroxylysine (GalHyl).	Lysine	74-80	myelin basic protein	Homo sapiens	45-48
9399586-7	1997	In addition, we showed that both S-MBP and L-MBP undergo hydroxylation of lysine and proline residues in collagen-like sequences, and that the hydroxylysine is glycosylated to form glucosylgalactosylhydroxylysine (GluGalHyl) and galactosylhydroxylysine (GalHyl).	Proline	85-92	myelin basic protein	Homo sapiens	35-38
9399586-7	1997	In addition, we showed that both S-MBP and L-MBP undergo hydroxylation of lysine and proline residues in collagen-like sequences, and that the hydroxylysine is glycosylated to form glucosylgalactosylhydroxylysine (GluGalHyl) and galactosylhydroxylysine (GalHyl).	Proline	85-92	myelin basic protein	Homo sapiens	45-48
9399586-8	1997	Hydroxylation was required for S-MBP to be assembled into large complexes, the apparent molecular sizes of which were estimated to be 200-1,300 kDa by SDS-PAGE under non-reducing conditions and gel filtration under non-denaturing conditions.	Sodium Dodecyl Sulfate	151-154	myelin basic protein	Homo sapiens	33-36
9236937-2	1997	A 52 kDa maltose binding-AgB fusion protein (rAgB.MBP) was produced and inclusion bodies containing the fusion protein were solubilised in urea and affinity purified on an amylose-Sepharose 6B column.	Maltose	9-16	myelin basic protein	Homo sapiens	50-53
9300722-10	1997	Recombinant hMBP enhanced TNF-alpha induction by MP2 as well as binding of FITC-MP2 to PBMCs.	Fluorescein-5-isothiocyanate	75-79	myelin basic protein	Homo sapiens	12-16
9300722-11	1997	In addition, incubation of serum with MP2-coated beads and analysis by SDS-PAGE resulted in the detection of a protein of approximately 33/34 kDa that could be partially removed by preincubating the serum with hMBP mAb.	Sodium Dodecyl Sulfate	71-74	myelin basic protein	Homo sapiens	210-214
9284169-10	1997	This was likely mediated, at least in part, by serum MBP, as rMBP bound strongly to 1D1 antigen in both thin-layer chromatography overlay and plate binding assays, the latter in a mannan-inhibitable manner.	Mannans	180-186	myelin basic protein	Homo sapiens	53-56
9281585-4	1997	The results indicate that transport requires a 21-nucleotide sequence, termed the RNA transport signal (RTS), in the 3" UTR of MBP mRNA.	21-nucleotide	47-60	myelin basic protein	Homo sapiens	127-130
9324307-5	1997	Two sizes of topologically closed domains were found in nucleoids of 0.51+/-0.17Mbp and 1.34+/-0.3 Mbp.	nucleoids	56-65	myelin basic protein	Homo sapiens	80-83
9257827-3	1997	In marked contrast, presentation of cross-reactive peptides of MBP p85-99 that act as weak agonists with B7-1, but not B7-2, costimulation resulted in significant T cell activation as measured by [3H]TdR incorporation and cytokine secretion.	Tritium	197-199	myelin basic protein	Homo sapiens	63-66
9307241-1	1997	This study analyzed the stability of the myelin basic protein (MBP)-specific T-cell receptor (TCR) repertoire during the course of multiple sclerosis (MS) in three patients who were monitored for three years by gadolinium-enhanced magnetic resonance imaging.	Gadolinium	211-221	myelin basic protein	Homo sapiens	63-66
9218510-5	1997	Out of 275 MBP-specific TCL, 178 (64.	Triclosan	24-27	myelin basic protein	Homo sapiens	11-14
9309217-2	1997	Maltodextrin/maltose-binding protein (MBP; M(r) = 40k) is a receptor protein which serves as an initial high-affinity binding component of the active-transport system of maltooligosaccharides in bacteria.	maltooligosaccharides	170-191	myelin basic protein	Homo sapiens	0-36
9309217-2	1997	Maltodextrin/maltose-binding protein (MBP; M(r) = 40k) is a receptor protein which serves as an initial high-affinity binding component of the active-transport system of maltooligosaccharides in bacteria.	maltooligosaccharides	170-191	myelin basic protein	Homo sapiens	38-41
9309217-3	1997	MBP also participates in chemotaxis towards maltooligosaccharides.	maltooligosaccharides	44-65	myelin basic protein	Homo sapiens	0-3
9309217-5	1997	In order to gain new understanding of the function of MBP, especially its versatility in binding different linear and cyclic oligosaccharides with similar affinities, we have undertaken high-resolution X-ray analysis of three oligosaccharide-bound structures.	Oligosaccharides	125-141	myelin basic protein	Homo sapiens	54-57
9309217-5	1997	In order to gain new understanding of the function of MBP, especially its versatility in binding different linear and cyclic oligosaccharides with similar affinities, we have undertaken high-resolution X-ray analysis of three oligosaccharide-bound structures.	Oligosaccharides	125-140	myelin basic protein	Homo sapiens	54-57
9309217-6	1997	RESULTS: The structures of MBP complexed with maltose, maltotriose and maltotetraose have been refined to high resolutions (1.67 to 1.8 A).	Maltose	46-53	myelin basic protein	Homo sapiens	27-30
9309217-6	1997	RESULTS: The structures of MBP complexed with maltose, maltotriose and maltotetraose have been refined to high resolutions (1.67 to 1.8 A).	maltotriose	55-66	myelin basic protein	Homo sapiens	27-30
9309217-6	1997	RESULTS: The structures of MBP complexed with maltose, maltotriose and maltotetraose have been refined to high resolutions (1.67 to 1.8 A).	maltotetraose	71-84	myelin basic protein	Homo sapiens	27-30
10743163-2	1997	The activity of the eosinophil cationic protein, major basic protein (MBP) on histamine release from human NEMCs has not been documented.	Histamine	78-87	myelin basic protein	Homo sapiens	70-73
10743163-3	1997	We examined the effects of MBP on histamine release from NEMCs.	Histamine	34-43	myelin basic protein	Homo sapiens	27-30
10743163-7	1997	MBP at the concentration of 10(-5) mol/L induced mild but statistically significant histamine release from the NEMCs.	Histamine	84-93	myelin basic protein	Homo sapiens	0-3
10743163-8	1997	Preincubation with MBP at the concentration of 1.57 x 10(-5) mol/L produced slight inhibition of subsequent HDM-induced histamine release but preincubation with HDM showed no effect on the subsequent MBP-induced or HDM-induced histamine release from NEMCs.	Histamine	120-129	myelin basic protein	Homo sapiens	19-22
10743163-8	1997	Preincubation with MBP at the concentration of 1.57 x 10(-5) mol/L produced slight inhibition of subsequent HDM-induced histamine release but preincubation with HDM showed no effect on the subsequent MBP-induced or HDM-induced histamine release from NEMCs.	Histamine	227-236	myelin basic protein	Homo sapiens	19-22
10743163-8	1997	Preincubation with MBP at the concentration of 1.57 x 10(-5) mol/L produced slight inhibition of subsequent HDM-induced histamine release but preincubation with HDM showed no effect on the subsequent MBP-induced or HDM-induced histamine release from NEMCs.	nemcs	250-255	myelin basic protein	Homo sapiens	19-22
10743163-9	1997	These results suggest that accumulated and activated eosinophils may release MBP resulting in clinical symptoms by interaction with NEMCs and inhibit of histamine release from NEMCs by subsequent interaction with allergen.	nemcs	132-137	myelin basic protein	Homo sapiens	77-80
9272635-2	1997	The protein kinase C (PKC)-activating tumor promoters mezerein and phorbol 12-myristate 13-acetate (PMA), but not the inactive phorbol ester analog 4alpha-PMA, caused a pronounced decrease of myelin basic protein (MBP) content and 2",3"-cyclic nucleotide 3"-phosphohydrolase (CNP) activity.	Tetradecanoylphorbol Acetate	67-98	myelin basic protein	Homo sapiens	192-212
9272635-2	1997	The protein kinase C (PKC)-activating tumor promoters mezerein and phorbol 12-myristate 13-acetate (PMA), but not the inactive phorbol ester analog 4alpha-PMA, caused a pronounced decrease of myelin basic protein (MBP) content and 2",3"-cyclic nucleotide 3"-phosphohydrolase (CNP) activity.	Tetradecanoylphorbol Acetate	67-98	myelin basic protein	Homo sapiens	214-217
9272635-2	1997	The protein kinase C (PKC)-activating tumor promoters mezerein and phorbol 12-myristate 13-acetate (PMA), but not the inactive phorbol ester analog 4alpha-PMA, caused a pronounced decrease of myelin basic protein (MBP) content and 2",3"-cyclic nucleotide 3"-phosphohydrolase (CNP) activity.	Tetradecanoylphorbol Acetate	100-103	myelin basic protein	Homo sapiens	192-212
9202313-0	1997	Demyelinating antibodies to myelin oligodendrocyte glycoprotein and galactocerebroside induce degradation of myelin basic protein in isolated human myelin.	galactocerebroside	68-86	myelin basic protein	Homo sapiens	109-129
9272635-2	1997	The protein kinase C (PKC)-activating tumor promoters mezerein and phorbol 12-myristate 13-acetate (PMA), but not the inactive phorbol ester analog 4alpha-PMA, caused a pronounced decrease of myelin basic protein (MBP) content and 2",3"-cyclic nucleotide 3"-phosphohydrolase (CNP) activity.	Tetradecanoylphorbol Acetate	100-103	myelin basic protein	Homo sapiens	214-217
9237101-1	1997	Copolymer 1 (Cop 1), a synthetic copolymer of amino acids, effective in suppression of experimental allergic encephalomyelitis (EAE) and myelin basic protein (MBP), was shown to bind extensively and promiscuously to the class II MHC molecules on antigen-presenting cells (APC) without prior processing.	copolymer	0-9	myelin basic protein	Homo sapiens	137-157
9237101-1	1997	Copolymer 1 (Cop 1), a synthetic copolymer of amino acids, effective in suppression of experimental allergic encephalomyelitis (EAE) and myelin basic protein (MBP), was shown to bind extensively and promiscuously to the class II MHC molecules on antigen-presenting cells (APC) without prior processing.	copolymer	0-9	myelin basic protein	Homo sapiens	159-162
9232633-6	1997	The zinc binding properties of myelin basic protein are metal specific, concentration dependent and pH dependent.	Metals	56-61	myelin basic protein	Homo sapiens	31-51
9310141-6	1997	Human glioma cells in which the MBP promoter was strongly active were sensitive to ganciclovir when they were transduced with MBP promoter/herpes simplex virus thymidine kinase gene-bearing retroviruses.	Ganciclovir	83-94	myelin basic protein	Homo sapiens	32-35
9310141-6	1997	Human glioma cells in which the MBP promoter was strongly active were sensitive to ganciclovir when they were transduced with MBP promoter/herpes simplex virus thymidine kinase gene-bearing retroviruses.	Ganciclovir	83-94	myelin basic protein	Homo sapiens	126-129
9129080-2	1997	By ELISA, calcium-dependent and mannan-inhibitable binding of human recombinant MBP (rMBP) to live M. avium was observed.	Mannans	32-38	myelin basic protein	Homo sapiens	80-83
9195953-2	1997	Resolution of detergent-soluble lysates prepared from LPS-treated, peripheral blood monocytes using Mono Q anion-exchange chromatography revealed two principal peaks of myelin basic protein kinase activity.	Mono Q	100-106	myelin basic protein	Homo sapiens	169-189
9195953-6	1997	In addition, the kinase phosphorylates peptide epsilon and myelin basic protein with equal efficiency but phosphorylates Kemptide and protamine sulfate poorly.	kemptide	121-129	myelin basic protein	Homo sapiens	59-79
9251242-3	1997	MBP has an unusual amino acid at Res-107 as a mixture of NG-monomethylarginine and NG, N"G-dimethylarginine.	res-107	33-40	myelin basic protein	Homo sapiens	0-3
9251242-3	1997	MBP has an unusual amino acid at Res-107 as a mixture of NG-monomethylarginine and NG, N"G-dimethylarginine.	ng-monomethylarginine	57-78	myelin basic protein	Homo sapiens	0-3
9251242-3	1997	MBP has an unusual amino acid at Res-107 as a mixture of NG-monomethylarginine and NG, N"G-dimethylarginine.	ng, n"g-dimethylarginine	83-107	myelin basic protein	Homo sapiens	0-3
9436467-5	1997	Chelation of extracellular Ca2+ selectively blocked the second, sustained rise in [Ca2+]i as well as MBP-induced histamine release.	Histamine	113-122	myelin basic protein	Homo sapiens	101-104
9184637-0	1997	In vitro modulation of human, autoreactive MBP-specific CD4 + T-cell clones by cyclosporin A.	Cyclosporine	79-92	myelin basic protein	Homo sapiens	43-46
9129080-2	1997	By ELISA, calcium-dependent and mannan-inhibitable binding of human recombinant MBP (rMBP) to live M. avium was observed.	Calcium	10-17	myelin basic protein	Homo sapiens	80-83
9125528-1	1997	When isolated from central nervous system myelin, myelin basic protein (MBP) exhibits charge microheterogeneity due to posttranslational deamidation, phosphorylation, and deimination of arginine to citrulline.	Arginine	186-194	myelin basic protein	Homo sapiens	50-70
9125392-2	1997	The (human) MBP epitope for MS anti-MBP is: Pro85-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro96.	Valine	50-53	myelin basic protein	Homo sapiens	12-15
9125392-2	1997	The (human) MBP epitope for MS anti-MBP is: Pro85-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro96.	Valine	50-53	myelin basic protein	Homo sapiens	36-39
9125392-2	1997	The (human) MBP epitope for MS anti-MBP is: Pro85-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro96.	Histidine	58-61	myelin basic protein	Homo sapiens	12-15
9125392-2	1997	The (human) MBP epitope for MS anti-MBP is: Pro85-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro96.	Histidine	58-61	myelin basic protein	Homo sapiens	36-39
9125392-2	1997	The (human) MBP epitope for MS anti-MBP is: Pro85-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro96.	Phenylalanine	62-65	myelin basic protein	Homo sapiens	12-15
9125392-2	1997	The (human) MBP epitope for MS anti-MBP is: Pro85-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro96.	Phenylalanine	62-65	myelin basic protein	Homo sapiens	36-39
9215565-1	1997	The maltose binding protein (MBP) has been site specifically labelled with a nitrobenzoxadiazole (NBD) group following mutation of a serine to a cysteine residue at position 337.	nitrobenzoxadiazole	77-96	myelin basic protein	Homo sapiens	29-32
9215565-1	1997	The maltose binding protein (MBP) has been site specifically labelled with a nitrobenzoxadiazole (NBD) group following mutation of a serine to a cysteine residue at position 337.	nbd	98-101	myelin basic protein	Homo sapiens	29-32
9215565-1	1997	The maltose binding protein (MBP) has been site specifically labelled with a nitrobenzoxadiazole (NBD) group following mutation of a serine to a cysteine residue at position 337.	Serine	133-139	myelin basic protein	Homo sapiens	29-32
9215565-1	1997	The maltose binding protein (MBP) has been site specifically labelled with a nitrobenzoxadiazole (NBD) group following mutation of a serine to a cysteine residue at position 337.	Cysteine	145-153	myelin basic protein	Homo sapiens	29-32
9130522-4	1997	ECP and, to a lesser extent MBP (0.3-3 microM), but not EDN and EPO, stimulated the release of histamine and tryptase from HHMC.	Histamine	95-104	myelin basic protein	Homo sapiens	28-31
9130522-6	1997	The activation of HHMC by ECP and MBP was abolished by preincubation with 2-deoxy-D-glucose and antimycin A.	Deoxyglucose	74-91	myelin basic protein	Homo sapiens	34-37
9130522-6	1997	The activation of HHMC by ECP and MBP was abolished by preincubation with 2-deoxy-D-glucose and antimycin A.	Antimycin A	96-107	myelin basic protein	Homo sapiens	34-37
9130522-7	1997	These data demonstrate that some eosinophil cationic proteins, ECP and MBP, are selective activators of HHMC, thus contributing to the cardiac lesions in patients with eosinophilia.	hhmc	104-108	myelin basic protein	Homo sapiens	71-74
9125528-1	1997	When isolated from central nervous system myelin, myelin basic protein (MBP) exhibits charge microheterogeneity due to posttranslational deamidation, phosphorylation, and deimination of arginine to citrulline.	Arginine	186-194	myelin basic protein	Homo sapiens	72-75
9125528-1	1997	When isolated from central nervous system myelin, myelin basic protein (MBP) exhibits charge microheterogeneity due to posttranslational deamidation, phosphorylation, and deimination of arginine to citrulline.	Citrulline	198-208	myelin basic protein	Homo sapiens	50-70
9125528-1	1997	When isolated from central nervous system myelin, myelin basic protein (MBP) exhibits charge microheterogeneity due to posttranslational deamidation, phosphorylation, and deimination of arginine to citrulline.	Citrulline	198-208	myelin basic protein	Homo sapiens	72-75
9144547-5	1997	In Tris-Cl buffer, the optimum pH for MBP-RNase H fusion protein is between 7.7 and 8.2.	tris-cl	3-10	myelin basic protein	Homo sapiens	38-41
9144547-6	1997	The MBP-RNase H fusion protein required 40 mM monovalent cation for its enzyme activity, whereas it showed lower activity at a salt concentration of more than 100 mM.	Salts	127-131	myelin basic protein	Homo sapiens	4-7
9128792-22	1997	Subtotal PTx is associated with a significant but transient decrease in SBP, DBP and MBP.	ptx	9-12	myelin basic protein	Homo sapiens	85-88
9208415-9	1997	The previously acquired folate depletion could affect normal appositional function of myelin basic protein molecules due to insufficient methylation of arginine in position 107.	Folic Acid	24-30	myelin basic protein	Homo sapiens	86-106
9176102-3	1997	MAP kinase activation was identified and quantified in Mono Q chromatography separated fractions of neutrophils that had been incubated with CPPD crystals by measuring [gamma-32P]adenosine triphosphate (ATP) phosphorylation of myelin basic protein and using immunoblotting techniques.	Calcium Pyrophosphate	141-145	myelin basic protein	Homo sapiens	227-247
9208415-9	1997	The previously acquired folate depletion could affect normal appositional function of myelin basic protein molecules due to insufficient methylation of arginine in position 107.	Arginine	152-160	myelin basic protein	Homo sapiens	86-106
9054563-0	1997	Salt-triggered intermembrane exchange of phospholipids and hemifusion by myelin basic protein.	Salts	0-4	myelin basic protein	Homo sapiens	73-93
9054563-0	1997	Salt-triggered intermembrane exchange of phospholipids and hemifusion by myelin basic protein.	Phospholipids	41-54	myelin basic protein	Homo sapiens	73-93
9054563-1	1997	Intervesicle phospholipid exchange through molecular contacts induced by the C1 molecular species of myelin basic protein (MBP) are characterized by using methods that amplify the effect of MBP-membrane interaction.	Phospholipids	13-25	myelin basic protein	Homo sapiens	101-121
9054563-1	1997	Intervesicle phospholipid exchange through molecular contacts induced by the C1 molecular species of myelin basic protein (MBP) are characterized by using methods that amplify the effect of MBP-membrane interaction.	Phospholipids	13-25	myelin basic protein	Homo sapiens	123-126
9054563-1	1997	Intervesicle phospholipid exchange through molecular contacts induced by the C1 molecular species of myelin basic protein (MBP) are characterized by using methods that amplify the effect of MBP-membrane interaction.	Phospholipids	13-25	myelin basic protein	Homo sapiens	190-193
9054563-7	1997	Thus, at 0.022 mol % of MBP and less than 100 mM KCl, it is possible to uncouple three sequential steps: (1) aggregation of vesicles by MBP; (2) apposition of bilayers and selective lipid exchange through vesicle-vesicle contacts established by MBP, i.e., anionic and zwitterionic phospholipids exchange, but cationic probes are excluded; and (3) hemifusion and lipid mixing of contacting monolayers of vesicles.	Potassium Chloride	49-52	myelin basic protein	Homo sapiens	136-139
9054563-7	1997	Thus, at 0.022 mol % of MBP and less than 100 mM KCl, it is possible to uncouple three sequential steps: (1) aggregation of vesicles by MBP; (2) apposition of bilayers and selective lipid exchange through vesicle-vesicle contacts established by MBP, i.e., anionic and zwitterionic phospholipids exchange, but cationic probes are excluded; and (3) hemifusion and lipid mixing of contacting monolayers of vesicles.	Potassium Chloride	49-52	myelin basic protein	Homo sapiens	136-139
9054563-7	1997	Thus, at 0.022 mol % of MBP and less than 100 mM KCl, it is possible to uncouple three sequential steps: (1) aggregation of vesicles by MBP; (2) apposition of bilayers and selective lipid exchange through vesicle-vesicle contacts established by MBP, i.e., anionic and zwitterionic phospholipids exchange, but cationic probes are excluded; and (3) hemifusion and lipid mixing of contacting monolayers of vesicles.	Phospholipids	281-294	myelin basic protein	Homo sapiens	24-27
9074491-2	1997	cDNA clones encoding bovine MBP were isolated from a bovine liver cDNA library using a cDNA fragment encoding a short collagen region, neck domain and carbohydrate recognition domain of human MBP.	Carbohydrates	151-163	myelin basic protein	Homo sapiens	192-195
9056251-2	1997	PP2A activity of HL-60 cells for phosphorylated myelin basic protein showed a sharp and transient increase after 18-h treatment with 1 microM retinoic acid, which corresponded to G1/S boundary of the cell cycle.	Tretinoin	142-155	myelin basic protein	Homo sapiens	48-68
9392438-7	1997	Crude PAK60 obtained from Mono Q chromatography of Jurkat cell extracts and purified placenta enzyme catalyzed phosphorylation of histone H4 and myelin basic protein as well as a variety of synthetic peptides previously identified as S6/H4 kinase substrates.	Mono Q	26-32	myelin basic protein	Homo sapiens	145-165
9063872-7	1997	Using a fusion protein made of MBP and the beta-subunit region encompassing amino acid residues Asp51-Pro110, we have studied the binding of spermine as a function of the ionic strength.	Spermine	141-149	myelin basic protein	Homo sapiens	31-34
9415374-4	1997	Digoxigenin-labeled MBP mRNA was microinjected into the treated cells and the extent of translocation of the microinjected RNA was determined by confocal microscopy.	Digoxigenin	0-11	myelin basic protein	Homo sapiens	20-23
9415374-5	1997	Nocodazole, taxol, and kinesin anti-sense oligonucleotide inhibited translocation of microinjected MBP mRNA, while cytochalasin B and kinesin sense oligonucleotide did not.	Nocodazole	0-10	myelin basic protein	Homo sapiens	99-102
9415374-5	1997	Nocodazole, taxol, and kinesin anti-sense oligonucleotide inhibited translocation of microinjected MBP mRNA, while cytochalasin B and kinesin sense oligonucleotide did not.	Paclitaxel	12-17	myelin basic protein	Homo sapiens	99-102
9415374-5	1997	Nocodazole, taxol, and kinesin anti-sense oligonucleotide inhibited translocation of microinjected MBP mRNA, while cytochalasin B and kinesin sense oligonucleotide did not.	Oligonucleotides	42-57	myelin basic protein	Homo sapiens	99-102
9444371-4	1997	The same applies for the deposition of Major Basic Protein (MBP) and treatment results, especially when topical steroids are found.	Steroids	112-120	myelin basic protein	Homo sapiens	39-58
9444371-4	1997	The same applies for the deposition of Major Basic Protein (MBP) and treatment results, especially when topical steroids are found.	Steroids	112-120	myelin basic protein	Homo sapiens	60-63
9165301-3	1997	The 1-2 Mbp giant DNA fragments were first observed 2 h after the T-24 cells were exposed to the active oxygen producing agents, or irradiated with x-ray.	Oxygen	104-110	myelin basic protein	Homo sapiens	8-11
9003389-3	1996	In the present work, we have found that MBP is phosphorylated by PITALRE complexes on both Ser and Thr residues.	Serine	91-94	myelin basic protein	Homo sapiens	40-43
9037707-5	1997	The conformation of the recombinant protein, excluding the inserted segment, closely resembles that of wild-type MBP in the closed maltose-bound form.	Maltose	131-138	myelin basic protein	Homo sapiens	113-116
8962082-6	1996	The maltose-binding protein-human FAS (MBP-hFAS) catalyzed palmitate synthesis from acetyl-CoA, malonyl-CoA, and NADPH and exhibited all of the partial activities of FAS at levels comparable with those of the native human enzyme purified from HepG2 cells.	Palmitates	59-68	myelin basic protein	Homo sapiens	39-42
8962082-6	1996	The maltose-binding protein-human FAS (MBP-hFAS) catalyzed palmitate synthesis from acetyl-CoA, malonyl-CoA, and NADPH and exhibited all of the partial activities of FAS at levels comparable with those of the native human enzyme purified from HepG2 cells.	Acetyl Coenzyme A	84-94	myelin basic protein	Homo sapiens	39-42
9003389-6	1996	In addition, our results suggest that one of the two MBP proline-directed threonine residues, Thr-97, is also selectively phosphorylated by PITALRE.	Proline	57-64	myelin basic protein	Homo sapiens	53-56
9003389-3	1996	In the present work, we have found that MBP is phosphorylated by PITALRE complexes on both Ser and Thr residues.	Threonine	99-102	myelin basic protein	Homo sapiens	40-43
9003389-6	1996	In addition, our results suggest that one of the two MBP proline-directed threonine residues, Thr-97, is also selectively phosphorylated by PITALRE.	Threonine	74-83	myelin basic protein	Homo sapiens	53-56
9003389-6	1996	In addition, our results suggest that one of the two MBP proline-directed threonine residues, Thr-97, is also selectively phosphorylated by PITALRE.	Threonine	94-97	myelin basic protein	Homo sapiens	53-56
8962082-6	1996	The maltose-binding protein-human FAS (MBP-hFAS) catalyzed palmitate synthesis from acetyl-CoA, malonyl-CoA, and NADPH and exhibited all of the partial activities of FAS at levels comparable with those of the native human enzyme purified from HepG2 cells.	Malonyl Coenzyme A	96-107	myelin basic protein	Homo sapiens	39-42
8962082-6	1996	The maltose-binding protein-human FAS (MBP-hFAS) catalyzed palmitate synthesis from acetyl-CoA, malonyl-CoA, and NADPH and exhibited all of the partial activities of FAS at levels comparable with those of the native human enzyme purified from HepG2 cells.	NADP	113-118	myelin basic protein	Homo sapiens	39-42
8962082-7	1996	Like the native HepG2 FAS, the products of MBP-hFAS are mainly palmitic acid (> 90%) and minimal amounts of stearic and arachidic acids.	Palmitic Acid	63-76	myelin basic protein	Homo sapiens	43-46
9003389-7	1996	These data, together with analysis of different peptide substrates derived from sites on MBP that are phosphorylated by PITALRE, indicate that PITALRE is a Ser/Thr proline-directed kinase.	Serine	156-159	myelin basic protein	Homo sapiens	89-92
9003389-5	1996	We have identified the proline-directed residue Ser-162 of MBP as a major phosphorylation site for PITALRE.	Proline	23-30	myelin basic protein	Homo sapiens	59-62
9003389-7	1996	These data, together with analysis of different peptide substrates derived from sites on MBP that are phosphorylated by PITALRE, indicate that PITALRE is a Ser/Thr proline-directed kinase.	Threonine	160-163	myelin basic protein	Homo sapiens	89-92
9003389-5	1996	We have identified the proline-directed residue Ser-162 of MBP as a major phosphorylation site for PITALRE.	Serine	48-51	myelin basic protein	Homo sapiens	59-62
9003389-7	1996	These data, together with analysis of different peptide substrates derived from sites on MBP that are phosphorylated by PITALRE, indicate that PITALRE is a Ser/Thr proline-directed kinase.	Proline	164-171	myelin basic protein	Homo sapiens	89-92
8962082-7	1996	Like the native HepG2 FAS, the products of MBP-hFAS are mainly palmitic acid (> 90%) and minimal amounts of stearic and arachidic acids.	stearic	111-118	myelin basic protein	Homo sapiens	43-46
8878556-6	1996	The A877D/D911A double mutant protein was also found to specifically dephosphorylate myelin basic protein phosphorylated on tyrosine.	Tyrosine	124-132	myelin basic protein	Homo sapiens	85-105
8962082-7	1996	Like the native HepG2 FAS, the products of MBP-hFAS are mainly palmitic acid (> 90%) and minimal amounts of stearic and arachidic acids.	Eicosanoic Acids	123-138	myelin basic protein	Homo sapiens	43-46
8965590-5	1996	METHODS: Mutations in the MBP gene were sought by sequence-specific oligonucleotide hybridisation, site-directed sequencing in Caucasian and Asian patients with HBV infection, and in HBsAg-negative controls.	Oligonucleotides	68-83	myelin basic protein	Homo sapiens	26-29
8862136-3	1996	Many MS patients and controls had T-cells responding to one or more cryptic MBP epitopes, as indicated by the generation of a peptide-specific T-cell line(s) by stimulation with synthetic peptides but not by stimulation with whole MBP.	Peptides	188-196	myelin basic protein	Homo sapiens	76-79
8912663-1	1996	Mannan-binding lectin (MBL), previously called "mannan-binding protein" or MBP, is a plasma C-type lectin which, upon binding to carbohydrate structures on micro-organisms, activates the classical pathway of complement.	Carbohydrates	129-141	myelin basic protein	Homo sapiens	75-78
10729885-6	1996	2 ml of TL-201 chloride (74 MBp) is injected to locate the leakage in the system with planar images with a gamma camera (Elscint SP 6), 30 min, 2, 3, and 24 h after injection.	Chlorides	15-23	myelin basic protein	Homo sapiens	28-31
8855323-5	1996	Heparan sulfate markedly reduced binding of the MBP-MOMP to cells, whereas chondroitin sulfate had no effect on binding.	Heparitin Sulfate	0-15	myelin basic protein	Homo sapiens	48-51
8855323-8	1996	Mutant cell lines defective in heparan sulfate synthesis but not chondroitin sulfate synthesis showed a marked reduction in the binding of MBP-MOMP and were also less susceptible to infection by chlamydiae.	Heparitin Sulfate	31-46	myelin basic protein	Homo sapiens	139-142
8660625-5	1996	3-Mbp cleavage fragment group by 137Cs gamma or Fe26+ (1.1 GeV/nucleon) irradiation vs the corresponding unirradiated DNA samples.	fe26+	48-53	myelin basic protein	Homo sapiens	2-5
8921412-1	1996	Mannan or mannose-binding protein (MBP) requires a novel serine protease termed MBP-associated serine protease (MASP) for activation of the complement cascade.	Mannans	0-6	myelin basic protein	Homo sapiens	10-33
8921412-1	1996	Mannan or mannose-binding protein (MBP) requires a novel serine protease termed MBP-associated serine protease (MASP) for activation of the complement cascade.	Mannans	0-6	myelin basic protein	Homo sapiens	35-38
8757629-4	1996	Activation of HHMC by ECP and MBP was Ca2+- and temperature-dependent and was abolished by preincubation (15 min, 37 degrees C) with 2-deoxy-D-glucose (10 mM) and antimycin A (1 microM).	Deoxyglucose	133-150	myelin basic protein	Homo sapiens	30-33
8757629-4	1996	Activation of HHMC by ECP and MBP was Ca2+- and temperature-dependent and was abolished by preincubation (15 min, 37 degrees C) with 2-deoxy-D-glucose (10 mM) and antimycin A (1 microM).	Antimycin A	163-174	myelin basic protein	Homo sapiens	30-33
8757629-5	1996	There was a significant correlation between the maximal percentage of histamine release induced by ECP and anti-IgE from HHMC (rs = 0.73; p < 0.005), by MBP and anti-IgE (rs = 0.79; p < 0.001), and by ECP and MBP (rs = 0.65; p < 0.005).	Histamine	70-79	myelin basic protein	Homo sapiens	215-218
9389050-1	1996	The expression of myelin basic protein (MBP) gene in the developing human brain was studied by using Northern dot blot and in situ hybridization with 32P- and biotin-labeled rat MBP cDNA and Diglabeled human MBP cRNA probes so as to explore the relation of temporal and spatial expression of human MBP gene to myelinogenesis and myelination.	Phosphorus-32	150-153	myelin basic protein	Homo sapiens	18-38
9389050-1	1996	The expression of myelin basic protein (MBP) gene in the developing human brain was studied by using Northern dot blot and in situ hybridization with 32P- and biotin-labeled rat MBP cDNA and Diglabeled human MBP cRNA probes so as to explore the relation of temporal and spatial expression of human MBP gene to myelinogenesis and myelination.	Phosphorus-32	150-153	myelin basic protein	Homo sapiens	40-43
9389050-1	1996	The expression of myelin basic protein (MBP) gene in the developing human brain was studied by using Northern dot blot and in situ hybridization with 32P- and biotin-labeled rat MBP cDNA and Diglabeled human MBP cRNA probes so as to explore the relation of temporal and spatial expression of human MBP gene to myelinogenesis and myelination.	Biotin	159-165	myelin basic protein	Homo sapiens	18-38
9389050-1	1996	The expression of myelin basic protein (MBP) gene in the developing human brain was studied by using Northern dot blot and in situ hybridization with 32P- and biotin-labeled rat MBP cDNA and Diglabeled human MBP cRNA probes so as to explore the relation of temporal and spatial expression of human MBP gene to myelinogenesis and myelination.	Biotin	159-165	myelin basic protein	Homo sapiens	40-43
9389051-5	1996	The expression level of MBP in this system was about 50 mg/L of bacterial culture estimate by immuno-dot blot, ELISA and absorbance scanning of SDS-PAGE.	Sodium Dodecyl Sulfate	144-147	myelin basic protein	Homo sapiens	24-27
8663100-4	1996	The activity of MAPK was tested in myelin basic protein (MBP)-containing polyacrylamide gels.	polyacrylamide	73-87	myelin basic protein	Homo sapiens	35-55
8663100-4	1996	The activity of MAPK was tested in myelin basic protein (MBP)-containing polyacrylamide gels.	polyacrylamide	73-87	myelin basic protein	Homo sapiens	57-60
8877375-8	1996	Rhesus MBP-A also has three cysteines at the N-terminus, similar to mouse and rat MBP-A and human MBP.	Cysteine	28-37	myelin basic protein	Homo sapiens	7-10
8836623-2	1996	Moreover, using a selective protein kinase C inhibitor, GF 109203X (3-[1-[3-(dimethylamino)propyl]-1 H-indol-3-yl]-4 (1 H-indol-3-yl)-1 H-pyrrole-2,5-dione monohydrochloride), we observed that protein kinase C was partially involved in the total MBP phosphorylation.	bisindolylmaleimide I	56-66	myelin basic protein	Homo sapiens	246-249
8687186-6	1996	The increase in mass was accounted for, in part, by the deimination of 18 of 19 arginyl residues to citrulline, making the patient"s MBP much less cationic than MBP from normal white matter.	Citrulline	100-110	myelin basic protein	Homo sapiens	133-136
8663400-0	1996	Maltose-binding protein containing an interdomain disulfide bridge confers a dominant-negative phenotype for transport and chemotaxis.	Disulfides	50-59	myelin basic protein	Homo sapiens	0-23
8663400-3	1996	In its closed form, the NH2-terminal and COOH-terminal domains of maltose-binding protein (MBP) are proposed to be aligned to allow residues in both domains to interact simultaneously with complementary sites on the MalF and MalG proteins of the maltodextrin uptake system or with the Tar chemotactic signal transducer.	maltodextrin	246-258	myelin basic protein	Homo sapiens	66-89
8663400-3	1996	In its closed form, the NH2-terminal and COOH-terminal domains of maltose-binding protein (MBP) are proposed to be aligned to allow residues in both domains to interact simultaneously with complementary sites on the MalF and MalG proteins of the maltodextrin uptake system or with the Tar chemotactic signal transducer.	maltodextrin	246-258	myelin basic protein	Homo sapiens	91-94
8663400-6	1996	We introduced cysteines (G69C and S337C) by site-directed mutagenesis into each domain of MBP and found that they formed an interdomain disulfide cross-link that should hold the protein in a closed conformation.	Cysteine	14-23	myelin basic protein	Homo sapiens	90-93
8663400-6	1996	We introduced cysteines (G69C and S337C) by site-directed mutagenesis into each domain of MBP and found that they formed an interdomain disulfide cross-link that should hold the protein in a closed conformation.	Disulfides	136-145	myelin basic protein	Homo sapiens	90-93
8663400-7	1996	This mutant MBP confers a dominant-negative phenotype for growth on maltose, for maltose transport, and for maltose chemotaxis.	Maltose	68-75	myelin basic protein	Homo sapiens	12-15
8663400-7	1996	This mutant MBP confers a dominant-negative phenotype for growth on maltose, for maltose transport, and for maltose chemotaxis.	Maltose	81-88	myelin basic protein	Homo sapiens	12-15
8663400-7	1996	This mutant MBP confers a dominant-negative phenotype for growth on maltose, for maltose transport, and for maltose chemotaxis.	Maltose	81-88	myelin basic protein	Homo sapiens	12-15
8687186-6	1996	The increase in mass was accounted for, in part, by the deimination of 18 of 19 arginyl residues to citrulline, making the patient"s MBP much less cationic than MBP from normal white matter.	arginyl	80-87	myelin basic protein	Homo sapiens	133-136
8706705-3	1996	Zinc ions stimulated the ADP-ribosyl cyclase activity of MBP-CD38, but inversely inhibited its NAD+ glycohydrolase activity which was approximately 100-fold dominant to the cyclase activity in the absence of Zn2+.	Zinc	208-212	myelin basic protein	Homo sapiens	57-60
8706705-5	1996	Zinc ions inhibited the NAD+ glycohydrolase reaction catalyzed by MBP-CD38 in an uncompetitive manner, whereas they enhanced the ADP-ribosyl cyclase reaction without affecting the Km value for NAD+.	NAD	24-28	myelin basic protein	Homo sapiens	66-69
8706705-6	1996	There was an increase in the fluorescence intensity of a hydrophobic fluorescent probe, 8-anilino-1-naphthalenesulfonate, in the presence of MBP-CD38.	8-anilino-1-naphthalenesulfonic acid	88-120	myelin basic protein	Homo sapiens	141-144
8706705-7	1996	The fluorescence increase was further enhanced by the addition of Zn2+ with a shift in the maximum emission wavelength from 484 nm to 470 nm, suggesting that Zn2+ caused conformational changes of MBP-CD38.	Zinc	66-70	myelin basic protein	Homo sapiens	196-199
8706705-7	1996	The fluorescence increase was further enhanced by the addition of Zn2+ with a shift in the maximum emission wavelength from 484 nm to 470 nm, suggesting that Zn2+ caused conformational changes of MBP-CD38.	Zinc	158-162	myelin basic protein	Homo sapiens	196-199
8662799-8	1996	Gangliosides also inhibited the NADase activity of the extracellular domain of CD38 antigen that was deprived of the transmembrane domain and was expressed in Escherichia coli as a fusion protein with maltose-binding protein (MBP-CD38).	Gangliosides	0-12	myelin basic protein	Homo sapiens	226-229
8735086-4	1996	The fusion polypeptide MBP-LLO411 was purified by maltose affinity chromatography and was further evaluated as a diagnostic antigen in a Western blot assay.	Maltose	50-57	myelin basic protein	Homo sapiens	23-26
8699022-1	1996	Clodronate (Cl2MBP; dichloromethylene-bisphosphonate)-containing liposomes are used to investigate the role of macrophages in immune and non-immune defense mechanisms by elimination of these macrophages followed by functional studies.	Clodronic Acid	0-10	myelin basic protein	Homo sapiens	15-18
8666820-9	1996	They were, however, at least partially charge mediated, since heparin abolished the effects of MBP on IL-1-stimulated cells, and the surrogate cationic molecule poly-L-arginine mimicked the stimulatory effects of MBP on fibroblast IL-6-type cytokine elaboration.	Heparin	62-69	myelin basic protein	Homo sapiens	95-98
8666820-9	1996	They were, however, at least partially charge mediated, since heparin abolished the effects of MBP on IL-1-stimulated cells, and the surrogate cationic molecule poly-L-arginine mimicked the stimulatory effects of MBP on fibroblast IL-6-type cytokine elaboration.	polyarginine	161-176	myelin basic protein	Homo sapiens	213-216
8662799-9	1996	The order of the inhibitory effect of purified ganglioside species on the NADase activity on MBP-CD38 was as follows: GQ1balpha > GT1b, GQ1b > GD1a, GD1b, GM1a, GM1b, GD3, GM3.	Gangliosides	47-58	myelin basic protein	Homo sapiens	93-96
8662799-9	1996	The order of the inhibitory effect of purified ganglioside species on the NADase activity on MBP-CD38 was as follows: GQ1balpha > GT1b, GQ1b > GD1a, GD1b, GM1a, GM1b, GD3, GM3.	gm1a	161-165	myelin basic protein	Homo sapiens	93-96
8662799-9	1996	The order of the inhibitory effect of purified ganglioside species on the NADase activity on MBP-CD38 was as follows: GQ1balpha > GT1b, GQ1b > GD1a, GD1b, GM1a, GM1b, GD3, GM3.	ganglioside M1b	167-171	myelin basic protein	Homo sapiens	93-96
8662799-9	1996	The order of the inhibitory effect of purified ganglioside species on the NADase activity on MBP-CD38 was as follows: GQ1balpha > GT1b, GQ1b > GD1a, GD1b, GM1a, GM1b, GD3, GM3.	gm3	178-181	myelin basic protein	Homo sapiens	93-96
8633070-2	1996	In transfected 293 cells, activation of the 45-kDa enzyme results in tyrosine-phosphorylated 46- and 56-kDa forms, which phosphorylate myelin basic protein.	Tyrosine	69-77	myelin basic protein	Homo sapiens	135-155
8813664-6	1996	It showed no cross-reactivity with antisera raised against soluble mammalian phosphatases and dephosphorylated a basic substrate (Tyr-phosphorylated myelin basic protein).	Tyrosine	130-133	myelin basic protein	Homo sapiens	149-169
8639575-4	1996	In the presence of ATP, the binding of MBP occurred only with phosphorylated protein.	Adenosine Triphosphate	19-22	myelin basic protein	Homo sapiens	39-42
8631744-3	1996	Five regions of E-selectin that differ in sequence from the corresponding regions of MBP have been introduced into the carbohydrate-recognition domain of MBP.	Carbohydrates	119-131	myelin basic protein	Homo sapiens	85-88
8613994-9	1996	In the presence of ATP and non-hydrolysable analogues, MBP is effectively released from GroEL, since the overall dissociation constant is reduced by three orders of magnitude.	Adenosine Triphosphate	19-22	myelin basic protein	Homo sapiens	55-58
8965119-2	1996	Copolymer 1 can suppress both acute and chronic relapsing EAE induced by either whole brain homogenate or the purified encephalitogens myelin basic protein (MBP) and proteolipid protein (PLP).	copolymer	0-9	myelin basic protein	Homo sapiens	135-155
8631744-3	1996	Five regions of E-selectin that differ in sequence from the corresponding regions of MBP have been introduced into the carbohydrate-recognition domain of MBP.	Carbohydrates	119-131	myelin basic protein	Homo sapiens	154-157
8634449-2	1996	The present studies in ara-C-treated U-937 cells extend these findings by demonstrating activation of a protein kinase that phosphorylates myelin basic protein (MBP).	Cytarabine	23-28	myelin basic protein	Homo sapiens	139-159
8634449-2	1996	The present studies in ara-C-treated U-937 cells extend these findings by demonstrating activation of a protein kinase that phosphorylates myelin basic protein (MBP).	Cytarabine	23-28	myelin basic protein	Homo sapiens	161-164
8924200-3	1996	The starting points for energy minimization were generated based on a framework that consists of a number of separated segments derived from the structure-known carbohydrate-recognition domain of the mannose-binding protein (MBP), which belongs to the same C-type lectin family as the selectin molecules do.	Carbohydrates	161-173	myelin basic protein	Homo sapiens	200-223
8641674-2	1996	The PP2A activity determined with myelin basic protein (MBP) as a substrate showed a sharp transient increase at 18 h of incubation of the cells with retinoic acid, whereas during incubation without retinoic acid, the activity remained at the initial level.	Tretinoin	150-163	myelin basic protein	Homo sapiens	34-54
8641674-2	1996	The PP2A activity determined with myelin basic protein (MBP) as a substrate showed a sharp transient increase at 18 h of incubation of the cells with retinoic acid, whereas during incubation without retinoic acid, the activity remained at the initial level.	Tretinoin	150-163	myelin basic protein	Homo sapiens	56-59
8924200-3	1996	The starting points for energy minimization were generated based on a framework that consists of a number of separated segments derived from the structure-known carbohydrate-recognition domain of the mannose-binding protein (MBP), which belongs to the same C-type lectin family as the selectin molecules do.	Carbohydrates	161-173	myelin basic protein	Homo sapiens	225-228
8645616-6	1996	Sucrose gradient assays performed with [3H]aldosterone-MBP-HBD revealed complex sedimenting at 8.3S and 4.9S with [3H]progesterone-MBP-HBD.	Sucrose	0-7	myelin basic protein	Homo sapiens	55-58
8543824-7	1996	In addition, anti-phosphotyrosine immunoprecipitates of IL-5-treated eosinophils contained enhanced phosphotransferase activity toward a myelin basic protein (MBP) peptide substrate when compared with control-treated eosinophils.	Phosphotyrosine	18-33	myelin basic protein	Homo sapiens	137-157
8543824-7	1996	In addition, anti-phosphotyrosine immunoprecipitates of IL-5-treated eosinophils contained enhanced phosphotransferase activity toward a myelin basic protein (MBP) peptide substrate when compared with control-treated eosinophils.	Phosphotyrosine	18-33	myelin basic protein	Homo sapiens	159-162
8745401-4	1996	The model was built based on information provided by X-ray structures of mannose binding protein (MBP) and E-selectin, both of which are members of the calcium-dependent (C-type) lectin superfamily.	Calcium	152-159	myelin basic protein	Homo sapiens	73-96
8745401-4	1996	The model was built based on information provided by X-ray structures of mannose binding protein (MBP) and E-selectin, both of which are members of the calcium-dependent (C-type) lectin superfamily.	Calcium	152-159	myelin basic protein	Homo sapiens	98-101
8838507-5	1996	Purified human serum lectin MBP was used to quantify the degree of exposed mannose or N-acetylglucosamine residues in the Fc region of anti-LTSRPA IgG of patients with RA and healthy controls.	Mannose	75-82	myelin basic protein	Homo sapiens	28-31
8838507-5	1996	Purified human serum lectin MBP was used to quantify the degree of exposed mannose or N-acetylglucosamine residues in the Fc region of anti-LTSRPA IgG of patients with RA and healthy controls.	Acetylglucosamine	86-105	myelin basic protein	Homo sapiens	28-31
8838507-9	1996	As MBP binding depends on exposed mannose or N-acetylglucosamine residues in the Fc region of the IgG molecule, these studies suggest that defective glycosylation of circulating anti-SK IgG may play a role in the etiology of RA.	Mannose	34-41	myelin basic protein	Homo sapiens	3-6
8838507-9	1996	As MBP binding depends on exposed mannose or N-acetylglucosamine residues in the Fc region of the IgG molecule, these studies suggest that defective glycosylation of circulating anti-SK IgG may play a role in the etiology of RA.	Acetylglucosamine	45-64	myelin basic protein	Homo sapiens	3-6
8645616-6	1996	Sucrose gradient assays performed with [3H]aldosterone-MBP-HBD revealed complex sedimenting at 8.3S and 4.9S with [3H]progesterone-MBP-HBD.	Sucrose	0-7	myelin basic protein	Homo sapiens	131-134
8645616-6	1996	Sucrose gradient assays performed with [3H]aldosterone-MBP-HBD revealed complex sedimenting at 8.3S and 4.9S with [3H]progesterone-MBP-HBD.	Tritium	40-42	myelin basic protein	Homo sapiens	55-58
8645616-6	1996	Sucrose gradient assays performed with [3H]aldosterone-MBP-HBD revealed complex sedimenting at 8.3S and 4.9S with [3H]progesterone-MBP-HBD.	Tritium	40-42	myelin basic protein	Homo sapiens	131-134
8645616-6	1996	Sucrose gradient assays performed with [3H]aldosterone-MBP-HBD revealed complex sedimenting at 8.3S and 4.9S with [3H]progesterone-MBP-HBD.	Tritium	115-117	myelin basic protein	Homo sapiens	55-58
8645616-6	1996	Sucrose gradient assays performed with [3H]aldosterone-MBP-HBD revealed complex sedimenting at 8.3S and 4.9S with [3H]progesterone-MBP-HBD.	Tritium	115-117	myelin basic protein	Homo sapiens	131-134
8645616-9	1996	These analyses demonstrated that the [3H]aldosterone-MBP-HBD complex is at least associated with hsp90 in reticulocyte lysate and that the HBD of hMR is sufficient to bind hsp90.	Tritium	38-40	myelin basic protein	Homo sapiens	53-56
8541554-1	1995	This study was undertaken to identify the signaling events involved in activation of neutrophil superoxide anion (O2-) production by eosinophil granule major basic protein (MBP).	Superoxides	96-112	myelin basic protein	Homo sapiens	173-176
8632715-6	1996	Partial purification of kinase activities using Mono Q anion-exchange chromatography demonstrated two major peaks of myelin basic protein kinase activity.	Mono Q	48-54	myelin basic protein	Homo sapiens	117-137
8541554-5	1995	Inhibition of MBP-stimulated O2- production by genistein and Western blot analysis using an antiphosphotyrosine antibody showed tyrosine kinase activation by MBP.	Superoxides	29-31	myelin basic protein	Homo sapiens	14-17
8541554-5	1995	Inhibition of MBP-stimulated O2- production by genistein and Western blot analysis using an antiphosphotyrosine antibody showed tyrosine kinase activation by MBP.	Genistein	47-56	myelin basic protein	Homo sapiens	14-17
8541554-1	1995	This study was undertaken to identify the signaling events involved in activation of neutrophil superoxide anion (O2-) production by eosinophil granule major basic protein (MBP).	Superoxides	114-116	myelin basic protein	Homo sapiens	173-176
8541554-6	1995	Calmodulin antagonists (calmidazolium and W-7) caused up to 80% inhibition of MBP-stimulated O2- production.	calmidazolium	24-37	myelin basic protein	Homo sapiens	78-81
8541554-2	1995	MBP did not produce an immediate increase in the cytosolic free calcium concentration ([Ca2+]i), characteristic of phospholipase C activation, but did cause a gradual increase in [Ca2+]i in cytochalasin B-treated cells.	Cytochalasin B	190-204	myelin basic protein	Homo sapiens	0-3
8541554-6	1995	Calmodulin antagonists (calmidazolium and W-7) caused up to 80% inhibition of MBP-stimulated O2- production.	W 7	42-45	myelin basic protein	Homo sapiens	78-81
8541554-4	1995	MBP did stimulate a low level of phospholipase D activity, as measured by a time-dependent increase in phosphatidic acid and, in the presence of 0.5% ethanol, phosphatidylethanol.	Phosphatidic Acids	103-120	myelin basic protein	Homo sapiens	0-3
8541554-6	1995	Calmodulin antagonists (calmidazolium and W-7) caused up to 80% inhibition of MBP-stimulated O2- production.	Superoxides	93-95	myelin basic protein	Homo sapiens	78-81
8847737-0	1995	Two mitogenic regions of myelin basic protein interact with different receptors to induce Schwann cell proliferation in a cAMP dependent process.	Cyclic AMP	122-126	myelin basic protein	Homo sapiens	25-45
8541554-4	1995	MBP did stimulate a low level of phospholipase D activity, as measured by a time-dependent increase in phosphatidic acid and, in the presence of 0.5% ethanol, phosphatidylethanol.	Ethanol	150-157	myelin basic protein	Homo sapiens	0-3
8847737-1	1995	Previous studies have shown that myelin basic protein (MBP) is mitogenic for Schwann cells (SCs) in the presence of elevated intracellular cAMP.	Cyclic AMP	139-143	myelin basic protein	Homo sapiens	33-53
8541554-4	1995	MBP did stimulate a low level of phospholipase D activity, as measured by a time-dependent increase in phosphatidic acid and, in the presence of 0.5% ethanol, phosphatidylethanol.	phosphatidylethanol	159-178	myelin basic protein	Homo sapiens	0-3
8847737-1	1995	Previous studies have shown that myelin basic protein (MBP) is mitogenic for Schwann cells (SCs) in the presence of elevated intracellular cAMP.	Cyclic AMP	139-143	myelin basic protein	Homo sapiens	55-58
8847737-8	1995	Furthermore, only MBP interacted with ganglioside GM1, whereas MBP did not interact with this ganglioside.	Gangliosides	38-49	myelin basic protein	Homo sapiens	18-21
8847737-8	1995	Furthermore, only MBP interacted with ganglioside GM1, whereas MBP did not interact with this ganglioside.	G(M1) Ganglioside	50-53	myelin basic protein	Homo sapiens	18-21
8746604-6	1995	At the end of cilazapril and hydrochlorothiazide administration significant decreases (p < 0.001) in SBP, DBP and MBP vs baseline values were observed.	Cilazapril	14-24	myelin basic protein	Homo sapiens	117-120
8847737-9	1995	These results are consistent with the view that ganglioside GM1 mediates the mitogenic effects of MBP, while the FGF receptor mediates the mitogenic effect of MBP.	Gangliosides	48-59	myelin basic protein	Homo sapiens	98-101
8847737-9	1995	These results are consistent with the view that ganglioside GM1 mediates the mitogenic effects of MBP, while the FGF receptor mediates the mitogenic effect of MBP.	G(M1) Ganglioside	60-63	myelin basic protein	Homo sapiens	98-101
8847737-10	1995	Intracellular cAMP of SCs was transiently increased after the addition of macrophage conditioned medium, suggesting that macrophages may produce factors in vivo which can transiently elevate intracellular cAMP levels, allowing a wave of SC proliferation in response to MBP-related mitogens.	Cyclic AMP	14-18	myelin basic protein	Homo sapiens	269-272
8847737-10	1995	Intracellular cAMP of SCs was transiently increased after the addition of macrophage conditioned medium, suggesting that macrophages may produce factors in vivo which can transiently elevate intracellular cAMP levels, allowing a wave of SC proliferation in response to MBP-related mitogens.	Cyclic AMP	205-209	myelin basic protein	Homo sapiens	269-272
8847738-0	1995	Exogenous myelin basic protein promotes oligodendrocyte death via increased calcium influx.	Calcium	76-83	myelin basic protein	Homo sapiens	10-30
8847738-3	1995	MBP and MBP peptides (1-44 and 88-151) have been shown to interact with ganglioside GM1 (Tzeng et al.	Gangliosides	72-83	myelin basic protein	Homo sapiens	0-3
8847738-3	1995	MBP and MBP peptides (1-44 and 88-151) have been shown to interact with ganglioside GM1 (Tzeng et al.	Gangliosides	72-83	myelin basic protein	Homo sapiens	8-11
8847738-3	1995	MBP and MBP peptides (1-44 and 88-151) have been shown to interact with ganglioside GM1 (Tzeng et al.	G(M1) Ganglioside	84-87	myelin basic protein	Homo sapiens	0-3
8847738-3	1995	MBP and MBP peptides (1-44 and 88-151) have been shown to interact with ganglioside GM1 (Tzeng et al.	G(M1) Ganglioside	84-87	myelin basic protein	Homo sapiens	8-11
8847738-6	1995	Therefore, using the fluorescent dye Indo-1 and an ACAS laser cytometer, we examined the level of intracellular calcium in OLGs after MBP treatment.	Calcium	112-119	myelin basic protein	Homo sapiens	134-137
8847738-7	1995	MBP was shown to provoke a rapid, dramatic, and sustained rise of intracellular calcium in most OLGs.	Calcium	80-87	myelin basic protein	Homo sapiens	0-3
8847738-10	1995	Incubation of cultured OLGs with MBP peptides (1-44 or 88-151) caused a modest and transitory elevation of intracellular calcium ions in a lower percentage of OLGs.	Calcium	121-128	myelin basic protein	Homo sapiens	33-36
8536709-3	1995	The relative molecular mass of the purified fusion protein (MBP-InsP3-5-phosphatase) was approximately M(r) 85,000 as analysed by SDS/PAGE.	Sodium Dodecyl Sulfate	130-133	myelin basic protein	Homo sapiens	60-63
7578098-0	1995	Kinetics of the reaction of a myelin basic protein peptide with soluble IAu.	iau	72-75	myelin basic protein	Homo sapiens	30-50
8583237-1	1995	A double blind Phase 1 clinical research project was conducted in vivo in multiple sclerosis (MS) patients to determine the effect of myelin basic protein (MBP) synthetic peptides on free (F) and bound (B) titers of anti-MBP in cerebrospinal fluid (CSF).	Peptides	171-179	myelin basic protein	Homo sapiens	134-154
8583237-1	1995	A double blind Phase 1 clinical research project was conducted in vivo in multiple sclerosis (MS) patients to determine the effect of myelin basic protein (MBP) synthetic peptides on free (F) and bound (B) titers of anti-MBP in cerebrospinal fluid (CSF).	Peptides	171-179	myelin basic protein	Homo sapiens	156-159
8583237-5	1995	Administration of MBP synthetic peptides to MS patients either intrathecally or intravenously did not have any adverse neurological effects and systemic complications did not occur.	Peptides	32-40	myelin basic protein	Homo sapiens	18-21
7487919-0	1995	The Gly-54-->Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease.	Glycine	4-7	myelin basic protein	Homo sapiens	42-65
7487919-0	1995	The Gly-54-->Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease.	Glycine	4-7	myelin basic protein	Homo sapiens	67-70
7487919-0	1995	The Gly-54-->Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease.	Aspartic Acid	16-19	myelin basic protein	Homo sapiens	42-65
7487919-0	1995	The Gly-54-->Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease.	Aspartic Acid	16-19	myelin basic protein	Homo sapiens	67-70
7487919-5	1995	A homozygous mutation at base pair 230 of the MBP gene results in a Gly-to-Asp substitution at the fifth collagen repeat.	Glycine	68-71	myelin basic protein	Homo sapiens	46-49
7487919-5	1995	A homozygous mutation at base pair 230 of the MBP gene results in a Gly-to-Asp substitution at the fifth collagen repeat.	Aspartic Acid	75-78	myelin basic protein	Homo sapiens	46-49
7487919-11	1995	Our results provide a biochemical basis for the functional deficit in the Gly-54-->Asp allelic form of MBP and suggest that the proMASP/MASP binding site maps to the fifth collagen repeat of MBP.	Glycine	74-77	myelin basic protein	Homo sapiens	106-109
7487919-11	1995	Our results provide a biochemical basis for the functional deficit in the Gly-54-->Asp allelic form of MBP and suggest that the proMASP/MASP binding site maps to the fifth collagen repeat of MBP.	Aspartic Acid	86-89	myelin basic protein	Homo sapiens	106-109
9345452-1	1995	We investigated two short tandem tetranucleotide (TGGA) repeat polymorphisms upstreams of the myelin basic protein (MBP) gene.	tetranucleotide	33-48	myelin basic protein	Homo sapiens	94-114
9345452-1	1995	We investigated two short tandem tetranucleotide (TGGA) repeat polymorphisms upstreams of the myelin basic protein (MBP) gene.	tetranucleotide	33-48	myelin basic protein	Homo sapiens	116-119
8746604-6	1995	At the end of cilazapril and hydrochlorothiazide administration significant decreases (p < 0.001) in SBP, DBP and MBP vs baseline values were observed.	Hydrochlorothiazide	29-48	myelin basic protein	Homo sapiens	117-120
8531225-0	1995	Localization and partial characterization of a 60 kDa citrulline-containing transport form of myelin basic protein from MO3-13 cells and human white matter.	Citrulline	54-64	myelin basic protein	Homo sapiens	94-114
7577962-0	1995	Aggregation of acidic lipid vesicles by myelin basic protein: dependence on potassium concentration.	Potassium	76-85	myelin basic protein	Homo sapiens	40-60
7577962-3	1995	Therefore, the effect of K+ concentration on the ability of MBP to aggregate large unilamellar vesicles (LUVs) containing phosphatidylcholine (PC) and 10-20% acidic lipid was investigated.	Phosphatidylcholines	122-141	myelin basic protein	Homo sapiens	60-63
7577962-3	1995	Therefore, the effect of K+ concentration on the ability of MBP to aggregate large unilamellar vesicles (LUVs) containing phosphatidylcholine (PC) and 10-20% acidic lipid was investigated.	Phosphatidylcholines	143-145	myelin basic protein	Homo sapiens	60-63
7584139-3	1995	Results presented here demonstrate that MBP also enhanced FcR-mediated phagocytosis by both monocytes and macrophages, and stimulated CR1-mediated phagocytosis in human culture-derived macrophages and in phorbol ester-activated monocytes.	Phorbol Esters	204-217	myelin basic protein	Homo sapiens	40-43
7545664-8	1995	The possibility that idiosyncratic appearance of a wide range of acyl substituents in myelin basic protein could be related to a peculiar involvement of ribosomal pseudouridine is mentioned.	Pseudouridine	163-176	myelin basic protein	Homo sapiens	86-106
7577962-7	1995	Concentrations of K+ above 150 mM caused dissociation of MBP from LUVs containing PC and a single acidic lipid.	Phosphatidylcholines	82-84	myelin basic protein	Homo sapiens	57-60
7577962-12	1995	Cholesterol and phosphatidylethanolamine together were found to be responsible for the greater MBP-mediated aggregation of Cyt.-LUVs and the greater TID labeling of MBP bound to Cyt.-LUVs compared to PC/acidic lipid LUVs.	Cholesterol	0-11	myelin basic protein	Homo sapiens	95-98
7577962-12	1995	Cholesterol and phosphatidylethanolamine together were found to be responsible for the greater MBP-mediated aggregation of Cyt.-LUVs and the greater TID labeling of MBP bound to Cyt.-LUVs compared to PC/acidic lipid LUVs.	Cholesterol	0-11	myelin basic protein	Homo sapiens	165-168
7577962-12	1995	Cholesterol and phosphatidylethanolamine together were found to be responsible for the greater MBP-mediated aggregation of Cyt.-LUVs and the greater TID labeling of MBP bound to Cyt.-LUVs compared to PC/acidic lipid LUVs.	phosphatidylethanolamine	16-40	myelin basic protein	Homo sapiens	95-98
7577962-12	1995	Cholesterol and phosphatidylethanolamine together were found to be responsible for the greater MBP-mediated aggregation of Cyt.-LUVs and the greater TID labeling of MBP bound to Cyt.-LUVs compared to PC/acidic lipid LUVs.	phosphatidylethanolamine	16-40	myelin basic protein	Homo sapiens	165-168
7575422-4	1995	Analysis of fractions from Mono Q anion-exchange chromatography of lysates of cells exposed to 10 mM Ca2+ or 100 ng/ml EGF revealed a peak of MBP phosphorylation activity that was coeluted with p42 and p44 MAPK as shown by immunoblot analysis.	Mono Q	27-33	myelin basic protein	Homo sapiens	142-145
8563142-11	1995	Mobilities on SDS-PAGE of the COOH-terminal collagenase-resistant fragment under reduced and non-reduced conditions indicate the presence of intrachain disulphide bonds, as are also found in mammalian MBP.	Sodium Dodecyl Sulfate	14-17	myelin basic protein	Homo sapiens	201-204
8563142-11	1995	Mobilities on SDS-PAGE of the COOH-terminal collagenase-resistant fragment under reduced and non-reduced conditions indicate the presence of intrachain disulphide bonds, as are also found in mammalian MBP.	disulphide	152-162	myelin basic protein	Homo sapiens	201-204
8531225-2	1995	The availability of antibodies to one of the components of MBP, i.e., the citrulline containing component ("C-8"), permitted us to localize this component of MBP to intracellular vacuoles and also on the external surface of the MO3-13 cells.	Citrulline	74-84	myelin basic protein	Homo sapiens	59-62
8531225-2	1995	The availability of antibodies to one of the components of MBP, i.e., the citrulline containing component ("C-8"), permitted us to localize this component of MBP to intracellular vacuoles and also on the external surface of the MO3-13 cells.	Citrulline	74-84	myelin basic protein	Homo sapiens	158-161
8587780-5	1995	Furthermore, for the first time we provided evidence that topical ketotifen administration could suppress the systemic upregulation of the blood eosinophil count and MBP level in subjects with pollinosis.	Ketotifen	66-75	myelin basic protein	Homo sapiens	166-169
7654231-2	1995	We reported that the release of major basic protein (MBP) from mature eosinophils stimulated with cytochalasin B and C5a were augmented after preincubation with recombinant ADF/TRX.	Cytochalasin B	98-112	myelin basic protein	Homo sapiens	32-51
7654231-2	1995	We reported that the release of major basic protein (MBP) from mature eosinophils stimulated with cytochalasin B and C5a were augmented after preincubation with recombinant ADF/TRX.	Cytochalasin B	98-112	myelin basic protein	Homo sapiens	53-56
7654231-3	1995	The addition of a TRX specific inhibitor, BE40644, suppressed the augmentation of MBP release from mature eosinophils.	BE 40644	42-49	myelin basic protein	Homo sapiens	82-85
8570016-2	1995	In a previous report we have shown that zinc binds to CNS myelin basic protein (MBP) in the presence of phosphate and this results in MBP aggregation.	Phosphates	104-113	myelin basic protein	Homo sapiens	58-78
8570016-2	1995	In a previous report we have shown that zinc binds to CNS myelin basic protein (MBP) in the presence of phosphate and this results in MBP aggregation.	Phosphates	104-113	myelin basic protein	Homo sapiens	80-83
7543541-6	1995	Preincubation of cells with 10 ng/ml IL-3 or IL-5 reduced the MBP concentrations required for histamine release by three- to fourfold and enhanced the rate of MBP-induced histamine release.	Histamine	171-180	myelin basic protein	Homo sapiens	159-162
7543541-2	1995	Preincubating basophil-containing mononuclear cells with 0.01 to 10 ng/ml IL-3 or IL-5 for 15 min at 37 degrees C caused a concentration-dependent enhancement of histamine release stimulated by 1.5 microM MBP.	Histamine	162-171	myelin basic protein	Homo sapiens	205-208
7543541-9	1995	MBP also stimulated low levels of leukotriene C4 (LTC4) release from basophils of 84 to 99% purity, and experiments using enriched (18-63%) basophil preparations demonstrated that preincubation with IL-3, IL-5, and GM-CSF also potentiated MBP-stimulated leukotriene C4 release up to threefold in parallel with histamine release.	Leukotrienes	34-45	myelin basic protein	Homo sapiens	0-3
7543541-4	1995	Preincubation with GM-CSF similarly enhanced MBP-induced histamine release.	Histamine	57-66	myelin basic protein	Homo sapiens	45-48
7543541-5	1995	A 10- to 15-min preincubation with IL-5 maximally increased the level of MBP-stimulated histamine release.	Histamine	88-97	myelin basic protein	Homo sapiens	73-76
7543541-9	1995	MBP also stimulated low levels of leukotriene C4 (LTC4) release from basophils of 84 to 99% purity, and experiments using enriched (18-63%) basophil preparations demonstrated that preincubation with IL-3, IL-5, and GM-CSF also potentiated MBP-stimulated leukotriene C4 release up to threefold in parallel with histamine release.	Leukotriene C4	34-48	myelin basic protein	Homo sapiens	0-3
7543541-6	1995	Preincubation of cells with 10 ng/ml IL-3 or IL-5 reduced the MBP concentrations required for histamine release by three- to fourfold and enhanced the rate of MBP-induced histamine release.	Histamine	94-103	myelin basic protein	Homo sapiens	62-65
7543541-9	1995	MBP also stimulated low levels of leukotriene C4 (LTC4) release from basophils of 84 to 99% purity, and experiments using enriched (18-63%) basophil preparations demonstrated that preincubation with IL-3, IL-5, and GM-CSF also potentiated MBP-stimulated leukotriene C4 release up to threefold in parallel with histamine release.	Histamine	310-319	myelin basic protein	Homo sapiens	0-3
7643383-11	1995	Incubation with the phospho-donor, acetyl phosphate, allowed both MBP-NarP and MBP-NarL to protect the -44.5 region of the aeg-46.5 operon control region from DNase I cleavage.	acetyl phosphate	35-51	myelin basic protein	Homo sapiens	66-69
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	pranidipine	12-17	myelin basic protein	Homo sapiens	141-161
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Serine	18-21	myelin basic protein	Homo sapiens	141-161
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Glutamine	22-25	myelin basic protein	Homo sapiens	141-161
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Lysine	26-29	myelin basic protein	Homo sapiens	141-161
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Arginine	30-33	myelin basic protein	Homo sapiens	141-161
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Proline	34-37	myelin basic protein	Homo sapiens	141-161
7643383-11	1995	Incubation with the phospho-donor, acetyl phosphate, allowed both MBP-NarP and MBP-NarL to protect the -44.5 region of the aeg-46.5 operon control region from DNase I cleavage.	acetyl phosphate	35-51	myelin basic protein	Homo sapiens	79-82
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Serine	38-41	myelin basic protein	Homo sapiens	141-161
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Glutamine	42-45	myelin basic protein	Homo sapiens	141-161
7643383-12	1995	Single and double nucleotide substitutions in the -44.5 region reduced or abolished nitrate and nitrite induction of aeg-46.5 operon expression in vivo and prevented the binding of MBP-NarP and MBP-NarL to the control region in vitro.	Nitrates	84-91	myelin basic protein	Homo sapiens	194-197
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Arginine	46-49	myelin basic protein	Homo sapiens	141-161
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Histidine	50-53	myelin basic protein	Homo sapiens	141-161
7643383-12	1995	Single and double nucleotide substitutions in the -44.5 region reduced or abolished nitrate and nitrite induction of aeg-46.5 operon expression in vivo and prevented the binding of MBP-NarP and MBP-NarL to the control region in vitro.	Nitrites	96-103	myelin basic protein	Homo sapiens	181-184
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Glycine	54-57	myelin basic protein	Homo sapiens	141-161
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Serine	38-41	myelin basic protein	Homo sapiens	141-161
7544282-1	1995	The peptide AcAla-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly-Ser-Lys-Tyr, which comprises the first 14 residues of the acetylated N-terminus of myelin basic protein, is an epitopic site for two monoclonal antibodies to the human protein.	Tyrosine	66-69	myelin basic protein	Homo sapiens	141-161
7643383-12	1995	Single and double nucleotide substitutions in the -44.5 region reduced or abolished nitrate and nitrite induction of aeg-46.5 operon expression in vivo and prevented the binding of MBP-NarP and MBP-NarL to the control region in vitro.	Nitrites	96-103	myelin basic protein	Homo sapiens	194-197
7541725-4	1995	Both Cop 1 and MBP bound to glutaraldehyde-fixed APC.	Glutaral	28-42	myelin basic protein	Homo sapiens	15-18
7558163-4	1995	The aim of the present investigation was to characterize the effects of these mutations on the physicochemical nature of MBP that is present in the circulation in vivo, and for this we used polyacrylamide gel electrophoresis, gel filtration and sucrose density gradient centrifugation, followed by immunoblotting and enhanced chemiluminescence.	polyacrylamide	190-204	myelin basic protein	Homo sapiens	121-124
7558163-4	1995	The aim of the present investigation was to characterize the effects of these mutations on the physicochemical nature of MBP that is present in the circulation in vivo, and for this we used polyacrylamide gel electrophoresis, gel filtration and sucrose density gradient centrifugation, followed by immunoblotting and enhanced chemiluminescence.	Sucrose	245-252	myelin basic protein	Homo sapiens	121-124
7558163-5	1995	The circulating wild-type MBP appeared to comprise a mixture of polymers formed from two to eight subunits (each based on three identical 32,000 MW polypeptide chains) of apparent molecular weights 200,000-700,000, with dimers and trimers constituting the predominant forms.	Polymers	64-72	myelin basic protein	Homo sapiens	26-29
7490014-3	1995	Antibodies to MBP was conjugated with horseradish peroxidase (HRP) by using modified periodate oxidation method.	metaperiodate	85-94	myelin basic protein	Homo sapiens	14-17
7542590-7	1995	CD59 cross-linking synergizes with sub-optimal doses of phorbol ester for activation of the protein kinase C and of the p42mapk, as shown by in vitro phosphorylation of histone HIIIS and myelin basic protein, respectively, and leads to CD25 but not CD69 expression.	Phorbol Esters	56-69	myelin basic protein	Homo sapiens	187-207
8948451-5	1995	Myelin basic protein was discovered to be a potent substrate for insulin-stimulated serine phosphorylation by the co-purified preparation, with the activity responsible having similar properties to the serine kinase activity towards the receptor.	Serine	84-90	myelin basic protein	Homo sapiens	0-20
8948451-6	1995	Myelin basic protein was also phosphorylated on serine by the NaCl eluate.	Serine	48-54	myelin basic protein	Homo sapiens	0-20
8948451-6	1995	Myelin basic protein was also phosphorylated on serine by the NaCl eluate.	Sodium Chloride	62-66	myelin basic protein	Homo sapiens	0-20
8948451-7	1995	Myelin basic protein phosphorylated by the co-purified preparation or the NaCl eluate gave the same set of phosphoserine peptides.	Sodium Chloride	74-78	myelin basic protein	Homo sapiens	0-20
8948451-7	1995	Myelin basic protein phosphorylated by the co-purified preparation or the NaCl eluate gave the same set of phosphoserine peptides.	Phosphoserine	107-120	myelin basic protein	Homo sapiens	0-20
8948451-8	1995	The major myelin basic protein serine kinase activity in the NaCl eluate co-purified exactly on Mono Q with the activity that restored insulin-stimulated insulin receptor serine phosphorylation.	Sodium Chloride	61-65	myelin basic protein	Homo sapiens	10-30
8948451-8	1995	The major myelin basic protein serine kinase activity in the NaCl eluate co-purified exactly on Mono Q with the activity that restored insulin-stimulated insulin receptor serine phosphorylation.	Mono Q	96-102	myelin basic protein	Homo sapiens	10-30
8948451-8	1995	The major myelin basic protein serine kinase activity in the NaCl eluate co-purified exactly on Mono Q with the activity that restored insulin-stimulated insulin receptor serine phosphorylation.	Serine	31-37	myelin basic protein	Homo sapiens	10-30
7490017-3	1995	There was a positive correlation between elevated levels of serum MBP and carbon dioxide partial pressure (PaCO2).	Carbon Dioxide	74-88	myelin basic protein	Homo sapiens	66-69
7490017-3	1995	There was a positive correlation between elevated levels of serum MBP and carbon dioxide partial pressure (PaCO2).	paco2	107-112	myelin basic protein	Homo sapiens	66-69
7550760-3	1995	MBP binds via the CRD to carbohydrate structures on microorganisms.	Carbohydrates	25-37	myelin basic protein	Homo sapiens	0-3
7538545-8	1995	Although it has been proposed that autoimmune disease could result from the failure of normal deletional mechanisms, this preliminary survey of MBP-reactive mature TCL from multiple sclerosis patients revealed that such cells are highly susceptible to TCR-induced PCD and comparable with TCL from normal subjects.	Triclosan	164-167	myelin basic protein	Homo sapiens	144-147
7771789-4	1995	The stimulation of PKC activity by H2O2 was associated with an increase in the activation of kinases phosphorylating myelin basic protein (MBP), a substrate for mitogen-activated protein (MAP) kinase and RRLSSLRA (S6 peptide; a substrate for the approximately 90-kDa ribosomal S6 kinases).	Hydrogen Peroxide	35-39	myelin basic protein	Homo sapiens	117-137
7771789-4	1995	The stimulation of PKC activity by H2O2 was associated with an increase in the activation of kinases phosphorylating myelin basic protein (MBP), a substrate for mitogen-activated protein (MAP) kinase and RRLSSLRA (S6 peptide; a substrate for the approximately 90-kDa ribosomal S6 kinases).	Hydrogen Peroxide	35-39	myelin basic protein	Homo sapiens	139-142
7536938-6	1995	Rolipram-treated and control animals equally developed circulating antibodies to myelin basic protein.	Rolipram	0-8	myelin basic protein	Homo sapiens	81-101
7707811-2	1995	A mutation in mannose binding protein (MBP) caused by point mutations in the MBP gene will lead to such a defect.	Mannose	14-21	myelin basic protein	Homo sapiens	39-42
7707811-2	1995	A mutation in mannose binding protein (MBP) caused by point mutations in the MBP gene will lead to such a defect.	Mannose	14-21	myelin basic protein	Homo sapiens	77-80
16695982-5	1995	The allele frequencies observed in the controls differed from those seen in normal white populations.Conclusions-The present study demonstrates a race specific pattern of allelic distribution within the tetranucleotide repeat of the MBP gene.	tetranucleotide	203-218	myelin basic protein	Homo sapiens	233-236
7534073-5	1995	However, when protein kinase C (PKC) was either inhibited by the PKC inhibitor GF 109203X or depleted by a prolonged TPA treatment, the stimulation of MBP phosphorylation by EGF was strongly inhibited.	bisindolylmaleimide I	79-89	myelin basic protein	Homo sapiens	151-154
7534073-5	1995	However, when protein kinase C (PKC) was either inhibited by the PKC inhibitor GF 109203X or depleted by a prolonged TPA treatment, the stimulation of MBP phosphorylation by EGF was strongly inhibited.	Tetradecanoylphorbol Acetate	117-120	myelin basic protein	Homo sapiens	151-154
7647290-6	1995	Upon fractionation on a Mono-Q column, 100 nM insulin increased the activity of 3 peaks which phosphorylated myelin basic protein.	Mono Q	24-30	myelin basic protein	Homo sapiens	109-129
7730143-1	1995	The lectin pathway is a novel pathway for activation of the complement cascade, which is initiated by the binding of mannose-binding protein (MBP) to its carbohydrate ligands.	Carbohydrates	154-166	myelin basic protein	Homo sapiens	117-140
7730143-1	1995	The lectin pathway is a novel pathway for activation of the complement cascade, which is initiated by the binding of mannose-binding protein (MBP) to its carbohydrate ligands.	Carbohydrates	154-166	myelin basic protein	Homo sapiens	142-145
7770063-4	1995	In contrast, two mannose-specific lectins, the mannan-binding protein (MBP) and serum amyloid P component (SAP), isolated from human serum, have inhibitory effects, both in the absence and presence of EGF.	Mannose	17-24	myelin basic protein	Homo sapiens	47-69
7770063-4	1995	In contrast, two mannose-specific lectins, the mannan-binding protein (MBP) and serum amyloid P component (SAP), isolated from human serum, have inhibitory effects, both in the absence and presence of EGF.	Mannose	17-24	myelin basic protein	Homo sapiens	71-74
7527821-5	1995	All-trans-retinoic acid (tRA) inhibited the proliferation of MBP-specific LNC in vitro.	Tretinoin	0-23	myelin basic protein	Homo sapiens	61-64
7527821-5	1995	All-trans-retinoic acid (tRA) inhibited the proliferation of MBP-specific LNC in vitro.	Tretinoin	25-28	myelin basic protein	Homo sapiens	61-64
7886644-10	1995	The delta MBP during apnoeic episodes showed a correlation with the decrease of nSaO2 (delta SaO2) (r2 = 0.30).	delta sao2	87-97	myelin basic protein	Homo sapiens	10-13
7886644-12	1995	Averaged delta MBP at an SaO2 of 7% and 5% oxygen was 12.6 (5.7) and 13.4 (3.6) mm Hg, respectively, whereas the averaged delta MBP at the same delta SaO2 during apnoeic episodes was 38.4 (15.5) and 45.2 (20.5) mm Hg, respectively.	Oxygen	43-49	myelin basic protein	Homo sapiens	15-18
7535576-1	1994	Degradation of purified myelin basic protein (MBP) was studied by SDS gel electrophoresis after addition of CSF samples obtained from HIV-1-infected patients.	Sodium Dodecyl Sulfate	66-69	myelin basic protein	Homo sapiens	46-49
7969157-10	1994	By using this antibody in an immune complex protein kinase assay, we have shown that treatment of human fibroblasts with serum or phorbol esters activates a myelin basic protein and histone H1 kinase activity in immunoprecipitates.	Phorbol Esters	130-144	myelin basic protein	Homo sapiens	157-177
7952596-5	1994	Major basic protein caused a significant increase in airway responsiveness to inhaled methacholine.	Methacholine Chloride	86-98	myelin basic protein	Homo sapiens	0-19
7523189-6	1994	Phosphoamino acid analysis demonstrated that the kinase domain of the epidermal growth factor receptor, p56lck and p60c-src phosphorylated myelin basic protein on tyrosines, that the protamine kinase phosphorylated myelin basic protein on serines, and that myelin basic protein kinase-1 phosphorylated myelin basic protein on threonines.	Phosphoamino Acids	0-17	myelin basic protein	Homo sapiens	139-159
7523189-6	1994	Phosphoamino acid analysis demonstrated that the kinase domain of the epidermal growth factor receptor, p56lck and p60c-src phosphorylated myelin basic protein on tyrosines, that the protamine kinase phosphorylated myelin basic protein on serines, and that myelin basic protein kinase-1 phosphorylated myelin basic protein on threonines.	Phosphoamino Acids	0-17	myelin basic protein	Homo sapiens	215-235
7523189-6	1994	Phosphoamino acid analysis demonstrated that the kinase domain of the epidermal growth factor receptor, p56lck and p60c-src phosphorylated myelin basic protein on tyrosines, that the protamine kinase phosphorylated myelin basic protein on serines, and that myelin basic protein kinase-1 phosphorylated myelin basic protein on threonines.	Phosphoamino Acids	0-17	myelin basic protein	Homo sapiens	215-235
7523189-6	1994	Phosphoamino acid analysis demonstrated that the kinase domain of the epidermal growth factor receptor, p56lck and p60c-src phosphorylated myelin basic protein on tyrosines, that the protamine kinase phosphorylated myelin basic protein on serines, and that myelin basic protein kinase-1 phosphorylated myelin basic protein on threonines.	Phosphoamino Acids	0-17	myelin basic protein	Homo sapiens	215-235
7523189-6	1994	Phosphoamino acid analysis demonstrated that the kinase domain of the epidermal growth factor receptor, p56lck and p60c-src phosphorylated myelin basic protein on tyrosines, that the protamine kinase phosphorylated myelin basic protein on serines, and that myelin basic protein kinase-1 phosphorylated myelin basic protein on threonines.	Tyrosine	163-172	myelin basic protein	Homo sapiens	139-159
7523189-6	1994	Phosphoamino acid analysis demonstrated that the kinase domain of the epidermal growth factor receptor, p56lck and p60c-src phosphorylated myelin basic protein on tyrosines, that the protamine kinase phosphorylated myelin basic protein on serines, and that myelin basic protein kinase-1 phosphorylated myelin basic protein on threonines.	Tyrosine	163-172	myelin basic protein	Homo sapiens	215-235
7523189-6	1994	Phosphoamino acid analysis demonstrated that the kinase domain of the epidermal growth factor receptor, p56lck and p60c-src phosphorylated myelin basic protein on tyrosines, that the protamine kinase phosphorylated myelin basic protein on serines, and that myelin basic protein kinase-1 phosphorylated myelin basic protein on threonines.	Tyrosine	163-172	myelin basic protein	Homo sapiens	215-235
7523189-6	1994	Phosphoamino acid analysis demonstrated that the kinase domain of the epidermal growth factor receptor, p56lck and p60c-src phosphorylated myelin basic protein on tyrosines, that the protamine kinase phosphorylated myelin basic protein on serines, and that myelin basic protein kinase-1 phosphorylated myelin basic protein on threonines.	Tyrosine	163-172	myelin basic protein	Homo sapiens	215-235
7523189-6	1994	Phosphoamino acid analysis demonstrated that the kinase domain of the epidermal growth factor receptor, p56lck and p60c-src phosphorylated myelin basic protein on tyrosines, that the protamine kinase phosphorylated myelin basic protein on serines, and that myelin basic protein kinase-1 phosphorylated myelin basic protein on threonines.	Serine	239-246	myelin basic protein	Homo sapiens	139-159
7523189-6	1994	Phosphoamino acid analysis demonstrated that the kinase domain of the epidermal growth factor receptor, p56lck and p60c-src phosphorylated myelin basic protein on tyrosines, that the protamine kinase phosphorylated myelin basic protein on serines, and that myelin basic protein kinase-1 phosphorylated myelin basic protein on threonines.	Threonine	326-336	myelin basic protein	Homo sapiens	139-159
7929060-5	1994	PTPL1 has a PTP domain located in the COOH terminus, and the protein was shown to dephosphorylate 32P-labeled myelin basic protein.	Carbonic Acid	38-42	myelin basic protein	Homo sapiens	110-130
7521366-7	1994	Because the second peak of MBP kinase activity (like the first) was active in the absence of added calcium and in the presence of 2 mM EGTA, it appears to be a type II, calcium-independent isoform of PKC.	Calcium	99-106	myelin basic protein	Homo sapiens	27-30
7521366-7	1994	Because the second peak of MBP kinase activity (like the first) was active in the absence of added calcium and in the presence of 2 mM EGTA, it appears to be a type II, calcium-independent isoform of PKC.	Egtazic Acid	135-139	myelin basic protein	Homo sapiens	27-30
7521366-7	1994	Because the second peak of MBP kinase activity (like the first) was active in the absence of added calcium and in the presence of 2 mM EGTA, it appears to be a type II, calcium-independent isoform of PKC.	Calcium	169-176	myelin basic protein	Homo sapiens	27-30
8071362-2	1994	The MBP-Raf fusions were purified by affinity chromatography on amylose resin and tested for binding to Ras.GTP indirectly by measuring their ability to inhibit the stimulation of Ras GTPase activity by GTPase activating protein (GAP120) in vitro.	Amylose	64-71	myelin basic protein	Homo sapiens	4-7
8071362-2	1994	The MBP-Raf fusions were purified by affinity chromatography on amylose resin and tested for binding to Ras.GTP indirectly by measuring their ability to inhibit the stimulation of Ras GTPase activity by GTPase activating protein (GAP120) in vitro.	Guanosine Triphosphate	108-111	myelin basic protein	Homo sapiens	4-7
7528819-1	1994	Treatment of cultured oligodendrocytes with a monoclonal antibody to galactocerebroside (GalC) triggers a cascade of events including the redistribution of membrane surface GalC over internal domains of MBP and loss of microtubular structures within the sheets (Dyer and Benjamins: J Neurosci 8:4307-4318, 1988; Dyer and Benjamins: J Neurosci Res 24:212-221, 1989).	galactocerebroside	69-87	myelin basic protein	Homo sapiens	203-206
7528819-3	1994	We now show that MBP and GalC, which are both initially Triton X-100 soluble, become Triton X-100 insoluble following anti-GalC binding and anti-GalC:GalC complex redistribution, suggesting that the surface anti-GalC: GalC complexes become associated with cytoplasmic MBP.	Octoxynol	56-68	myelin basic protein	Homo sapiens	17-20
7528819-3	1994	We now show that MBP and GalC, which are both initially Triton X-100 soluble, become Triton X-100 insoluble following anti-GalC binding and anti-GalC:GalC complex redistribution, suggesting that the surface anti-GalC: GalC complexes become associated with cytoplasmic MBP.	Octoxynol	85-97	myelin basic protein	Homo sapiens	17-20
7999252-5	1994	Following purification on an amylose column, 15 mg pure MBP-ECD per litre of culture were produced, which was 5% of the total bacterial protein.	Amylose	29-36	myelin basic protein	Homo sapiens	56-59
7516311-8	1994	The conclusion that the interferon-activated MBP kinase in peak 1 could be accounted for by an activated MAP kinase was also supported by the finding that fractions from Mono Q peak 1 demonstrated activity towards a MAP kinase-specific substrate.	Mono Q	170-176	myelin basic protein	Homo sapiens	45-48
7515950-3	1994	Although purified human MBP migrates as a single band on sodium dodecyl sulfate-polyacrylamide gel electrophoresis with a molecular mass of 20 kDa, the microheterogeneity that is masked under these conditions can be clearly demonstrated on alkaline-urea gels at pH 10.6.	Sodium Dodecyl Sulfate	57-79	myelin basic protein	Homo sapiens	24-27
7515950-3	1994	Although purified human MBP migrates as a single band on sodium dodecyl sulfate-polyacrylamide gel electrophoresis with a molecular mass of 20 kDa, the microheterogeneity that is masked under these conditions can be clearly demonstrated on alkaline-urea gels at pH 10.6.	polyacrylamide	80-94	myelin basic protein	Homo sapiens	24-27
7515950-3	1994	Although purified human MBP migrates as a single band on sodium dodecyl sulfate-polyacrylamide gel electrophoresis with a molecular mass of 20 kDa, the microheterogeneity that is masked under these conditions can be clearly demonstrated on alkaline-urea gels at pH 10.6.	Urea	249-253	myelin basic protein	Homo sapiens	24-27
7515882-7	1994	Insulin and TPA also stimulated MAPK (> 2-fold increase over basal, with myelin basic protein as a substrate).	Tetradecanoylphorbol Acetate	12-15	myelin basic protein	Homo sapiens	76-96
7515903-1	1994	In the present study a tetranucleotide (TGGA)n repeat polymorphism 5" to the myelin basic protein (MBP) gene was evaluated in a group of HLA-class II-typed, chronic progressive multiple sclerosis (MS) patients.	tetranucleotide	23-38	myelin basic protein	Homo sapiens	77-97
7515903-1	1994	In the present study a tetranucleotide (TGGA)n repeat polymorphism 5" to the myelin basic protein (MBP) gene was evaluated in a group of HLA-class II-typed, chronic progressive multiple sclerosis (MS) patients.	tetranucleotide	23-38	myelin basic protein	Homo sapiens	99-102
8022414-13	1994	Increasing concentrations of myelin basic protein as a PKC-alpha or -delta substrate also caused increased potency of inhibition by UCN-01.	7-hydroxystaurosporine	132-138	myelin basic protein	Homo sapiens	29-49
7520088-3	1994	Membrane depolarization and decrease in phosphorylation of MBP and CNPase can also be elicited by inhibition of the inward rectifier with Ba2+ but not by inhibition of outward K+ channels with 4-aminopyridine or tetraethylammonium.	N-methyl-valyl-amiclenomycin	138-142	myelin basic protein	Homo sapiens	59-62
7520088-3	1994	Membrane depolarization and decrease in phosphorylation of MBP and CNPase can also be elicited by inhibition of the inward rectifier with Ba2+ but not by inhibition of outward K+ channels with 4-aminopyridine or tetraethylammonium.	4-Aminopyridine	193-208	myelin basic protein	Homo sapiens	59-62
7520088-3	1994	Membrane depolarization and decrease in phosphorylation of MBP and CNPase can also be elicited by inhibition of the inward rectifier with Ba2+ but not by inhibition of outward K+ channels with 4-aminopyridine or tetraethylammonium.	Tetraethylammonium	212-230	myelin basic protein	Homo sapiens	59-62
8058064-4	1994	Zymography of immunoprecipitated ERKs in myelin basic protein (MBP)-containing polyacrylamide gels demonstrated dose-dependent induction of ERK-1 and -2 activity by IGF-1 in GC cells with maximal activity occurring at 6 min.	polyacrylamide	79-93	myelin basic protein	Homo sapiens	41-61
8058064-4	1994	Zymography of immunoprecipitated ERKs in myelin basic protein (MBP)-containing polyacrylamide gels demonstrated dose-dependent induction of ERK-1 and -2 activity by IGF-1 in GC cells with maximal activity occurring at 6 min.	polyacrylamide	79-93	myelin basic protein	Homo sapiens	63-66
7513612-6	1994	Myelin basic protein phosphotransferase activity eluted at 0.44 M NaCl, but Western blot analysis revealed that this could not be ascribed to mitogen-activated protein (MAP) kinases.	Sodium Chloride	66-70	myelin basic protein	Homo sapiens	0-20
7513612-8	1994	In addition to myelin basic protein, it phosphorylated S6 peptide analogues and histone H1 on seryl residues.	seryl	94-99	myelin basic protein	Homo sapiens	15-35
7518704-0	1994	Myelin basic protein interaction with zinc and phosphate: fluorescence studies on the water-soluble form of the protein.	Phosphates	47-56	myelin basic protein	Homo sapiens	0-20
7518704-0	1994	Myelin basic protein interaction with zinc and phosphate: fluorescence studies on the water-soluble form of the protein.	Water	86-91	myelin basic protein	Homo sapiens	0-20
7518704-1	1994	The interaction of myelin basic protein (MBP) with zinc and phosphate ions has been studied by using the emission properties of the single tryptophan residue of the protein (Trp-115).	Phosphates	60-69	myelin basic protein	Homo sapiens	19-39
7518704-1	1994	The interaction of myelin basic protein (MBP) with zinc and phosphate ions has been studied by using the emission properties of the single tryptophan residue of the protein (Trp-115).	Phosphates	60-69	myelin basic protein	Homo sapiens	41-44
7518704-1	1994	The interaction of myelin basic protein (MBP) with zinc and phosphate ions has been studied by using the emission properties of the single tryptophan residue of the protein (Trp-115).	Tryptophan	139-149	myelin basic protein	Homo sapiens	19-39
7518704-1	1994	The interaction of myelin basic protein (MBP) with zinc and phosphate ions has been studied by using the emission properties of the single tryptophan residue of the protein (Trp-115).	Tryptophan	139-149	myelin basic protein	Homo sapiens	41-44
7518704-1	1994	The interaction of myelin basic protein (MBP) with zinc and phosphate ions has been studied by using the emission properties of the single tryptophan residue of the protein (Trp-115).	Tryptophan	174-177	myelin basic protein	Homo sapiens	19-39
7518704-1	1994	The interaction of myelin basic protein (MBP) with zinc and phosphate ions has been studied by using the emission properties of the single tryptophan residue of the protein (Trp-115).	Tryptophan	174-177	myelin basic protein	Homo sapiens	41-44
7518704-3	1994	The addition of either zinc to MBP in the presence of phosphate or phosphate to MBP in the presence of zinc resulted in an increase of fluorescence intensity and a blue shift of the emission maximum wavelength.	Phosphates	54-63	myelin basic protein	Homo sapiens	31-34
7518704-3	1994	The addition of either zinc to MBP in the presence of phosphate or phosphate to MBP in the presence of zinc resulted in an increase of fluorescence intensity and a blue shift of the emission maximum wavelength.	Phosphates	54-63	myelin basic protein	Homo sapiens	80-83
7518704-3	1994	The addition of either zinc to MBP in the presence of phosphate or phosphate to MBP in the presence of zinc resulted in an increase of fluorescence intensity and a blue shift of the emission maximum wavelength.	Phosphates	67-76	myelin basic protein	Homo sapiens	80-83
8018603-1	1994	Mannose-binding protein (MBP) plays an important role in host defense by recognizing sugar residues on certain pathogens and activating the complement cascade.	Sugars	85-90	myelin basic protein	Homo sapiens	0-23
8018603-1	1994	Mannose-binding protein (MBP) plays an important role in host defense by recognizing sugar residues on certain pathogens and activating the complement cascade.	Sugars	85-90	myelin basic protein	Homo sapiens	25-28
7510762-4	1994	Complexes of human HLA-DR2 (DRB1*1501/DRB5*0101) and a peptide analog from human myelin basic protein MBP(84-102) containing a 6 histidine tag (6 x His) and a tyrosine residue at the N-terminus end [6 x His-MBP(83-102)Y83] were prepared and purified.	Histidine	129-138	myelin basic protein	Homo sapiens	102-105
7510762-4	1994	Complexes of human HLA-DR2 (DRB1*1501/DRB5*0101) and a peptide analog from human myelin basic protein MBP(84-102) containing a 6 histidine tag (6 x His) and a tyrosine residue at the N-terminus end [6 x His-MBP(83-102)Y83] were prepared and purified.	Histidine	148-151	myelin basic protein	Homo sapiens	81-101
7510762-4	1994	Complexes of human HLA-DR2 (DRB1*1501/DRB5*0101) and a peptide analog from human myelin basic protein MBP(84-102) containing a 6 histidine tag (6 x His) and a tyrosine residue at the N-terminus end [6 x His-MBP(83-102)Y83] were prepared and purified.	Tyrosine	159-167	myelin basic protein	Homo sapiens	81-101
7510762-4	1994	Complexes of human HLA-DR2 (DRB1*1501/DRB5*0101) and a peptide analog from human myelin basic protein MBP(84-102) containing a 6 histidine tag (6 x His) and a tyrosine residue at the N-terminus end [6 x His-MBP(83-102)Y83] were prepared and purified.	Tyrosine	159-167	myelin basic protein	Homo sapiens	102-105
7510762-4	1994	Complexes of human HLA-DR2 (DRB1*1501/DRB5*0101) and a peptide analog from human myelin basic protein MBP(84-102) containing a 6 histidine tag (6 x His) and a tyrosine residue at the N-terminus end [6 x His-MBP(83-102)Y83] were prepared and purified.	Histidine	203-206	myelin basic protein	Homo sapiens	102-105
7510762-7	1994	The quantitation of bound peptide in the eluted complexes showed 100% occupancy of HLA-DR2 (DRB1*1501/DRB5*0101) with [6 x His-MBP(83-102)Y83] peptide with a recovery of 50-75%.	Histidine	123-126	myelin basic protein	Homo sapiens	127-130
7510762-10	1994	Finally, we demonstrate that both MBP(84-102) and [6 x His-MBP(83-102)Y83] peptides were equally capable of stimulating restricted T cell line in the presence of autologous antigen presenting cells (APCs).	Histidine	55-58	myelin basic protein	Homo sapiens	59-62
7515291-1	1994	We have previously shown that CNS myelin basic protein (MBP) can be purified in the lipid-bound, native-like form by using a procedure based on myelin solubilization with detergents at pH above 7, and on the filter-like use of hydroxyapatite to separate non-adsorbed MBP from other myelin proteins.	Durapatite	227-241	myelin basic protein	Homo sapiens	34-54
7515291-1	1994	We have previously shown that CNS myelin basic protein (MBP) can be purified in the lipid-bound, native-like form by using a procedure based on myelin solubilization with detergents at pH above 7, and on the filter-like use of hydroxyapatite to separate non-adsorbed MBP from other myelin proteins.	Durapatite	227-241	myelin basic protein	Homo sapiens	56-59
7515291-2	1994	Here, we report on the isolation of MBP in the zwitterionic detergent 3-((3-cholamidopropyl)dimethylammonio)-1-propane sulfonate (CHAPS), which does not interfere at 280 nm and can be removed by dialysis.	3-((3-cholamidopropyl)dimethylammonio)-1-propane sulfonate	70-128	myelin basic protein	Homo sapiens	36-39
7515291-2	1994	Here, we report on the isolation of MBP in the zwitterionic detergent 3-((3-cholamidopropyl)dimethylammonio)-1-propane sulfonate (CHAPS), which does not interfere at 280 nm and can be removed by dialysis.	3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate	130-135	myelin basic protein	Homo sapiens	36-39
8297360-2	1994	The kinase activity, measured by phosphorylation of myelin basic protein, increased concurrently with tyrosine phosphorylation.	Tyrosine	102-110	myelin basic protein	Homo sapiens	52-72
7903874-7	1994	Increased tyrosine phosphorylation of MAP kinase following IL-12 stimulation was also associated with enhanced enzymatic activity of this protein in vitro as measured by myelin basic protein phosphotransferase assay.	Tyrosine	10-18	myelin basic protein	Homo sapiens	170-190
8162055-0	1994	Distribution of trinucleotide repeat sequences across a 2 Mbp region containing the Huntington"s disease gene.	trinucleotide	16-29	myelin basic protein	Homo sapiens	58-61
8162055-2	1994	We report here the identification of all ten classes of trinucleotide repeats within a 2 Mbp region of 4p16.3 containing the Huntington"s disease (HD) gene.	trinucleotide	56-69	myelin basic protein	Homo sapiens	89-92
7507225-6	1994	We showed that citrulline affects antigen recognition by some TCL that are specific for areas of MBP that contain the citrulline residues.	Citrulline	15-25	myelin basic protein	Homo sapiens	97-100
7507225-6	1994	We showed that citrulline affects antigen recognition by some TCL that are specific for areas of MBP that contain the citrulline residues.	Citrulline	118-128	myelin basic protein	Homo sapiens	97-100
8145293-8	1993	2) RT4-AC and RT4-D also express a low level of MBP mRNA upon forskolin treatment.	Colforsin	62-71	myelin basic protein	Homo sapiens	48-51
7691962-4	1993	We show here that T cell clones specific for the N-terminal fragment of myelin basic protein, acetylated Ac1-11, recognize a set of unrelated peptides in the context of the same I-Au molecule.	Gold	180-182	myelin basic protein	Homo sapiens	72-92
8407952-8	1993	Mck1 isolated from yeast extracts by immunoprecipitation with an anti-Mck1 antibody directed against its C terminus also phosphorylated MBP at serine.	Serine	143-149	myelin basic protein	Homo sapiens	136-139
8267903-11	1993	CONCLUSIONS: Activation of the classical complement pathway by retrovirus envelope proteins can be initiated by the binding of MBP to carbohydrate side chains of envelope glycoproteins.	Carbohydrates	134-146	myelin basic protein	Homo sapiens	127-130
8373787-1	1993	The interaction of myelin basic protein (MBP) with single bilayers on a solid support (planar and spherical support) is studied by deuterium nuclear magnetic resonance (2H-NMR), differential scanning calorimetry (DSC) and polarized attenuated total reflection infrared spectroscopy (ATR-IR).	Deuterium	131-140	myelin basic protein	Homo sapiens	19-39
8373787-1	1993	The interaction of myelin basic protein (MBP) with single bilayers on a solid support (planar and spherical support) is studied by deuterium nuclear magnetic resonance (2H-NMR), differential scanning calorimetry (DSC) and polarized attenuated total reflection infrared spectroscopy (ATR-IR).	Deuterium	131-140	myelin basic protein	Homo sapiens	41-44
8373787-1	1993	The interaction of myelin basic protein (MBP) with single bilayers on a solid support (planar and spherical support) is studied by deuterium nuclear magnetic resonance (2H-NMR), differential scanning calorimetry (DSC) and polarized attenuated total reflection infrared spectroscopy (ATR-IR).	Deuterium	169-171	myelin basic protein	Homo sapiens	19-39
8373787-1	1993	The interaction of myelin basic protein (MBP) with single bilayers on a solid support (planar and spherical support) is studied by deuterium nuclear magnetic resonance (2H-NMR), differential scanning calorimetry (DSC) and polarized attenuated total reflection infrared spectroscopy (ATR-IR).	Deuterium	169-171	myelin basic protein	Homo sapiens	41-44
8373787-11	1993	NMR relaxation time measurements in the headgroup and chain region of DMPG and DMPC suggest that the lateral diffusion coefficient of the acidic lipid decreases significantly due to the coupling with MBP while the zwitterionic DMPC is not affected.	dimyristoylphosphatidylglycerol	70-74	myelin basic protein	Homo sapiens	200-203
8373787-11	1993	NMR relaxation time measurements in the headgroup and chain region of DMPG and DMPC suggest that the lateral diffusion coefficient of the acidic lipid decreases significantly due to the coupling with MBP while the zwitterionic DMPC is not affected.	Dimyristoylphosphatidylcholine	79-83	myelin basic protein	Homo sapiens	200-203
8375396-8	1993	In the presence of the classical PKC activators phosphatidylserine/diacylglycerol, PKC alpha phosphorylates a PKC-alpha pseudosubstrate-derived peptide, an epidermal-growth-factor-receptor-derived peptide, histone III-S and myelin basic protein to an equal extent, whilst PKC zeta phosphorylates only the PKC-alpha-derived peptide.	Phosphatidylserines	48-66	myelin basic protein	Homo sapiens	224-244
8375396-8	1993	In the presence of the classical PKC activators phosphatidylserine/diacylglycerol, PKC alpha phosphorylates a PKC-alpha pseudosubstrate-derived peptide, an epidermal-growth-factor-receptor-derived peptide, histone III-S and myelin basic protein to an equal extent, whilst PKC zeta phosphorylates only the PKC-alpha-derived peptide.	Diglycerides	67-81	myelin basic protein	Homo sapiens	224-244
8375396-9	1993	However, arachidonic acid greatly diminishes PKC-alpha activity towards the epidermal-growth-factor-receptor-derived peptide, histone III-S and myelin basic protein, but enhances PKC-zeta activity towards the PKC-alpha-derived peptide.	Arachidonic Acid	9-25	myelin basic protein	Homo sapiens	144-164
8255972-0	1993	Human mannose-binding protein gene is regulated by interleukins, dexamethasone and heat shock.	Dexamethasone	65-78	myelin basic protein	Homo sapiens	6-29
8255972-5	1993	MBP mRNA expression in HuH-7 cells was increased by interleukin-6 (IL-6), dexamethasone and heat shock, decreased by interleukin 1 (IL-1), and unaffected by interferon gamma (IFN gamma), tumour necrosis factor alpha (TNF alpha) and transforming growth factor beta (TGF beta).	Dexamethasone	74-87	myelin basic protein	Homo sapiens	0-3
8255972-7	1993	Human MBP is an acute-phase protein, and transcription of its gene is enhanced by IL-6, dexamethasone and heat shock but inhibited by IL-1.	Dexamethasone	88-101	myelin basic protein	Homo sapiens	6-9
8373631-0	1993	Human serum mannose binding protein (MBP): development of an enzyme-linked immunosorbent assay (ELISA) and determination of levels in serum from 1085 normal Japanese and in some body fluids.	Mannose	12-19	myelin basic protein	Homo sapiens	37-40
8344453-2	1993	We investigated the mitogenic effect of these growth factors on quiescent mature oligodendrocytes (OL) expressing myelin basic protein (MBP) in OL cultures that were treated for 3 days with cytosine arabinoside (ARA-C) in order to kill O-2A precursors which divide in chemically defined medium.	Cytarabine	190-210	myelin basic protein	Homo sapiens	136-139
8328957-1	1993	Collectin receptor (Clq receptor) has been shown to bind human Clq, mannose-binding protein (MBP), lung surfactant protein A (SP-A) and bovine conglutinin.	(R)-chloroquine	20-23	myelin basic protein	Homo sapiens	68-91
8328957-1	1993	Collectin receptor (Clq receptor) has been shown to bind human Clq, mannose-binding protein (MBP), lung surfactant protein A (SP-A) and bovine conglutinin.	(R)-chloroquine	20-23	myelin basic protein	Homo sapiens	93-96
7684065-0	1993	Binding at an NFI site is modulated by cyclic AMP-dependent activation of myelin basic protein gene expression.	Cyclic AMP	39-49	myelin basic protein	Homo sapiens	74-94
7683738-2	1993	Amplification of a polymorphic tetranucleotide repeat region immediately 5" to MBP exon 1 demonstrated the presence of eight different alleles among members of 14 multiplex multiple sclerosis families (36 affected individuals).	tetranucleotide	31-46	myelin basic protein	Homo sapiens	79-82
7688546-1	1993	Protein phosphorylation and subsequent dephosphorylation was studied in digitonin-permeabilized neuroblastoma SH-SY5Y cells by measuring the incorporation of [32P]phosphate into myelin basic protein (MBP).	Digitonin	72-81	myelin basic protein	Homo sapiens	178-198
7688546-1	1993	Protein phosphorylation and subsequent dephosphorylation was studied in digitonin-permeabilized neuroblastoma SH-SY5Y cells by measuring the incorporation of [32P]phosphate into myelin basic protein (MBP).	Digitonin	72-81	myelin basic protein	Homo sapiens	200-203
7681838-1	1993	Basic fibroblast growth factor (FGF) induced a rapid increase in tyrosine phosphorylation of a 57-kDa cytoplasmic protein with functional myelin basic protein kinase activity and antigenic properties common to mitogen-activated kinases or extracellular signal-regulated kinases.	Tyrosine	65-73	myelin basic protein	Homo sapiens	138-158
8385431-6	1993	MBP, PF4, or cathepsin G induced a 2- to 3-fold increase in airway responsiveness 1 h after instillation, as assessed by the dose of inhaled methacholine required to increase total lung resistance by 100%.	Methacholine Chloride	141-153	myelin basic protein	Homo sapiens	0-3
7681099-6	1993	Experiments with a structure inducer, 15% 1-propanol in buffer, reveal that the refolding pattern of MBP in reverse micelles is specific to the membrane biomimetic system and is not produced by organic solvent per se.	1-Propanol	42-52	myelin basic protein	Homo sapiens	101-104
8383965-4	1993	The enzyme induced by either stimulant bound strongly to phenyl-Sepharose, had a molecular mass of 40 kDa on gel filtration and phosphorylated three MAP kinase substrates, i.e. MAP, myelin basic protein and the T669 peptide.	phenyl-sepharose	57-73	myelin basic protein	Homo sapiens	182-202
7679432-1	1993	Acetylated peptide 1-9 from human myelin basic protein induces experimental allergic encephalomyelitis in PL/J mice through I-Au and TCR V beta 8.2.	i-au	124-128	myelin basic protein	Homo sapiens	34-54
7679637-2	1993	The interaction of myelin basic protein (MBP) with large unilamellar vesicles, composed of phosphatidylserine (PtdSer), phosphatidylserine/phosphatidylcholine (PtdSer/Ole2GroPCho) and phosphatidylcholine/cholesterol (Ole2GroPCho/cholesterol) was examined.	Phosphatidylserines	91-109	myelin basic protein	Homo sapiens	19-39
7679637-2	1993	The interaction of myelin basic protein (MBP) with large unilamellar vesicles, composed of phosphatidylserine (PtdSer), phosphatidylserine/phosphatidylcholine (PtdSer/Ole2GroPCho) and phosphatidylcholine/cholesterol (Ole2GroPCho/cholesterol) was examined.	Phosphatidylserines	91-109	myelin basic protein	Homo sapiens	41-44
7679637-2	1993	The interaction of myelin basic protein (MBP) with large unilamellar vesicles, composed of phosphatidylserine (PtdSer), phosphatidylserine/phosphatidylcholine (PtdSer/Ole2GroPCho) and phosphatidylcholine/cholesterol (Ole2GroPCho/cholesterol) was examined.	Phosphatidylserines	111-117	myelin basic protein	Homo sapiens	41-44
8389045-4	1993	Acute intravenous sodium chloride load induced a significant increase of the mean arterial pressure (MBP) only when the patients were on the high sodium diet.	Sodium Chloride	18-33	myelin basic protein	Homo sapiens	101-104
8389045-4	1993	Acute intravenous sodium chloride load induced a significant increase of the mean arterial pressure (MBP) only when the patients were on the high sodium diet.	Sodium	18-24	myelin basic protein	Homo sapiens	101-104
8389045-5	1993	This increase of the MBP was associated with a significantly lower increment of plasma ANP, cGMP, lower decrement of ALDO and PRA when compared to normal- or low- sodium intake.	Cyclic GMP	92-96	myelin basic protein	Homo sapiens	21-24
8389045-5	1993	This increase of the MBP was associated with a significantly lower increment of plasma ANP, cGMP, lower decrement of ALDO and PRA when compared to normal- or low- sodium intake.	Sodium	163-169	myelin basic protein	Homo sapiens	21-24
8421844-1	1993	Mannan-binding protein (MBP) is a newly discovered serum protein which activates the complement system by the classical pathway by binding to mannose-rich surfaces on microorganisms.	Mannose	142-149	myelin basic protein	Homo sapiens	0-22
8421844-1	1993	Mannan-binding protein (MBP) is a newly discovered serum protein which activates the complement system by the classical pathway by binding to mannose-rich surfaces on microorganisms.	Mannose	142-149	myelin basic protein	Homo sapiens	24-27
7678038-1	1993	Myelin basic protein (MBP) from common goldfish (Carassius auratus) myelin was extracted with dilute mineral acid.	mineral acid	101-113	myelin basic protein	Homo sapiens	22-25
7678038-6	1993	We have also examined the urea alkaline gel profile of the goldfish MBP together with the human C-1, C-2, C-3, C-4, and C-8 components.	Urea	26-30	myelin basic protein	Homo sapiens	68-71
1293508-0	1992	Morphological changes in Krebs II ascites tumour cells induced by insulin are associated with differences in protein composition and altered amounts of free, cytoskeletal-bound and membrane-bound polysomes.	krebs	25-30	myelin basic protein	Homo sapiens	181-205
1477092-1	1992	Mannan-binding protein (MBP) is a lectin which, upon binding to certain carbohydrates, activates the classical pathway of complement without the involvement of antibody or C1q.	Carbohydrates	72-85	myelin basic protein	Homo sapiens	24-27
1477092-3	1992	An amino acid substitution in the exon 1 at codon 54 in the MBP gene (GGC [glycine] to GAC [aspartic acid]) has been shown to be closely associated with low MBP concentration in Caucasoids.	Glycine	75-82	myelin basic protein	Homo sapiens	60-63
1477092-3	1992	An amino acid substitution in the exon 1 at codon 54 in the MBP gene (GGC [glycine] to GAC [aspartic acid]) has been shown to be closely associated with low MBP concentration in Caucasoids.	Glycine	75-82	myelin basic protein	Homo sapiens	157-160
1477092-3	1992	An amino acid substitution in the exon 1 at codon 54 in the MBP gene (GGC [glycine] to GAC [aspartic acid]) has been shown to be closely associated with low MBP concentration in Caucasoids.	Aspartic Acid	92-105	myelin basic protein	Homo sapiens	60-63
1477092-3	1992	An amino acid substitution in the exon 1 at codon 54 in the MBP gene (GGC [glycine] to GAC [aspartic acid]) has been shown to be closely associated with low MBP concentration in Caucasoids.	Aspartic Acid	92-105	myelin basic protein	Homo sapiens	157-160
1295884-4	1992	Inhibition of phosphorylation by mitoxantrone was observed with various substrates including S6 peptide, myelin basic protein and its peptide substrate derived from the amino-terminal region.	Mitoxantrone	33-45	myelin basic protein	Homo sapiens	105-125
1460414-1	1992	Serum mannose-binding protein (MBP) is a C-type lectin that binds to terminal mannose and N-acetylglucosamine moieties present on surfaces of certain pathogens and activates the classical complement pathway.	Mannose	6-13	myelin basic protein	Homo sapiens	31-34
1460414-1	1992	Serum mannose-binding protein (MBP) is a C-type lectin that binds to terminal mannose and N-acetylglucosamine moieties present on surfaces of certain pathogens and activates the classical complement pathway.	Mannose	78-85	myelin basic protein	Homo sapiens	31-34
1460414-1	1992	Serum mannose-binding protein (MBP) is a C-type lectin that binds to terminal mannose and N-acetylglucosamine moieties present on surfaces of certain pathogens and activates the classical complement pathway.	Acetylglucosamine	90-109	myelin basic protein	Homo sapiens	31-34
1460414-3	1992	The human serum MBP fraction was obtained by sequential affinity chromatography on mannan-Sepharose, anti-IgM-Sepharose and anti-MBP-Sepharose in the presence of calcium ions.	Mannans	83-89	myelin basic protein	Homo sapiens	16-19
1296827-1	1992	In earlier studies, we described a technique for the "in vivo" depletion of macrophages, using liposome-encapsulated dichloromethylene bisphosphonate (C12MBP).	Clodronic Acid	117-149	myelin basic protein	Homo sapiens	154-157
1280063-1	1992	The serum-type mannose-binding protein (MBP) is a defense molecule that has carbohydrate-dependent bactericidal effects.	Carbohydrates	76-88	myelin basic protein	Homo sapiens	15-38
1280063-1	1992	The serum-type mannose-binding protein (MBP) is a defense molecule that has carbohydrate-dependent bactericidal effects.	Carbohydrates	76-88	myelin basic protein	Homo sapiens	40-43
1281679-0	1992	Effects of acyl chain length on the conformation of myelin basic protein bound to lysolipid micelles.	lysolipid	82-91	myelin basic protein	Homo sapiens	52-72
1281679-1	1992	The interactions of myelin basic protein with micelles of lysophosphatidylcholine detergents of different acyl chain lengths were investigated by circular dichroism (CD), small-angle X-ray scattering, Fourier transform infrared spectroscopy (FT-IR), and 1H, 13C and 31P nuclear magnetic resonance spectroscopy (NMR).	Lysophosphatidylcholines	58-81	myelin basic protein	Homo sapiens	20-40
1281679-1	1992	The interactions of myelin basic protein with micelles of lysophosphatidylcholine detergents of different acyl chain lengths were investigated by circular dichroism (CD), small-angle X-ray scattering, Fourier transform infrared spectroscopy (FT-IR), and 1H, 13C and 31P nuclear magnetic resonance spectroscopy (NMR).	Hydrogen	254-256	myelin basic protein	Homo sapiens	20-40
1281679-1	1992	The interactions of myelin basic protein with micelles of lysophosphatidylcholine detergents of different acyl chain lengths were investigated by circular dichroism (CD), small-angle X-ray scattering, Fourier transform infrared spectroscopy (FT-IR), and 1H, 13C and 31P nuclear magnetic resonance spectroscopy (NMR).	13c	258-261	myelin basic protein	Homo sapiens	20-40
1284472-0	1992	Tetranucleotide repeat polymorphism at the human myelin basic protein gene (MBP).	tetranucleotide	0-15	myelin basic protein	Homo sapiens	49-69
1284472-0	1992	Tetranucleotide repeat polymorphism at the human myelin basic protein gene (MBP).	tetranucleotide	0-15	myelin basic protein	Homo sapiens	76-79
1338597-2	1992	Supplementation of MgO elicited a significant fall in averaged mean blood pressure calculated with a 24-h ambulatory blood pressure monitoring system (MBP) in EH from a baseline value of 104.3 +/- 12.2 to 99.5 +/- 11.6 mmHg (p < 0.05), while controls remained unaltered from a baseline value of 85.1 +/- 11.5 to 84.5 +/- 13.3 mmHg.	Magnesium Oxide	19-22	myelin basic protein	Homo sapiens	151-154
1338597-8	1992	A significant negative correlation existed between the pretreatment PRA and changes in MBP after magnesium supplementation in EH (r = -0.65, p < 0.01), and there was a significant positive correlation between changes in PATPI and changes in MBP as a whole (r = 0.41, p < 0.05).	Magnesium	97-106	myelin basic protein	Homo sapiens	87-90
1379237-5	1992	Moreover, the deletion of sequences outside of the receptor footprinted region (MBP-TRE-18) resulted in a higher triiodothyronine responsiveness and a concomitant increase in receptor-dependent, hormone-independent repression.	Triiodothyronine	113-129	myelin basic protein	Homo sapiens	80-83
1379237-6	1992	Results of transfection assays showed that both receptors alpha and beta elicit indistinguishable triiodothyronine responses when the MBP-TRE functions as a regulator of a heterologous promoter activity.	Triiodothyronine	98-114	myelin basic protein	Homo sapiens	134-137
1365545-3	1992	MBP appears to selectively recognize an array of apparently disparate oligosaccharides that decorate gram-negative and gram-positive bacteria as well as certain parasites, yeasts, and fungi.	Oligosaccharides	70-86	myelin basic protein	Homo sapiens	0-3
1352285-5	1992	Sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed that the content of both MBP-E1 alpha and E1 beta polypeptides was markedly increased in the presence of overexpressed chaperonin proteins.	sodium dodecyl sulfate-polyacrylamide	0-37	myelin basic protein	Homo sapiens	90-93
1352285-7	1992	The functional MBP-E1 fusion protein from ES- double transformants were purified by amylose resin affinity chromatography.	Amylose	84-91	myelin basic protein	Homo sapiens	15-18
1352285-8	1992	The MBP moiety was removed by subsequent digestion with Factor Xa endoprotease, followed by Sephacryl S-300HR chromatography.	sephacryl s	92-103	myelin basic protein	Homo sapiens	4-7
1501242-3	1992	Liposomes prepared from synthetic phospholipids were used as targets for MBP and their properties examined by fluorescence and circular dichroism (CD) spectroscopy.	Phospholipids	34-47	myelin basic protein	Homo sapiens	73-76
1501242-4	1992	MBP caused a change in the temperature transition profiles of acidic liposomes (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidyl serine or an equimolar mixture of 1,2-dimyristoyl-sn-glycero-3-phosphocholine and 1,2-dimyristoyl-sn-glycero-3-phosphatidic acid) and induced their aggregation as shown by fluorescence resonance energy transfer experiments.	1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidyl serine	80-133	myelin basic protein	Homo sapiens	0-3
1501242-4	1992	MBP caused a change in the temperature transition profiles of acidic liposomes (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidyl serine or an equimolar mixture of 1,2-dimyristoyl-sn-glycero-3-phosphocholine and 1,2-dimyristoyl-sn-glycero-3-phosphatidic acid) and induced their aggregation as shown by fluorescence resonance energy transfer experiments.	Dimyristoylphosphatidylcholine	161-204	myelin basic protein	Homo sapiens	0-3
1501242-4	1992	MBP caused a change in the temperature transition profiles of acidic liposomes (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidyl serine or an equimolar mixture of 1,2-dimyristoyl-sn-glycero-3-phosphocholine and 1,2-dimyristoyl-sn-glycero-3-phosphatidic acid) and induced their aggregation as shown by fluorescence resonance energy transfer experiments.	dimyristoylphosphatidic acid	209-255	myelin basic protein	Homo sapiens	0-3
1501242-6	1992	Blue shifts in the emission maxima of the Trp, and of the dimethylaminonaphthyl moiety in acrylodan-labeled MBP, and a reduction in the effectiveness of quenching of Trp fluorescence by acrylamide were observed in the presence of acidic lipids.	dimethylaminonaphthyl	58-79	myelin basic protein	Homo sapiens	108-111
1501242-6	1992	Blue shifts in the emission maxima of the Trp, and of the dimethylaminonaphthyl moiety in acrylodan-labeled MBP, and a reduction in the effectiveness of quenching of Trp fluorescence by acrylamide were observed in the presence of acidic lipids.	acrylodan	90-99	myelin basic protein	Homo sapiens	108-111
1630577-9	1992	Silver impregnated nerve fibres showed only MBP immunoreactivity.	Silver	0-6	myelin basic protein	Homo sapiens	44-47
1374408-0	1992	The N terminus of human myelin basic protein consists of C2, C4, C6, and C8 alkyl carboxylic acids.	alkyl carboxylic acids	76-98	myelin basic protein	Homo sapiens	24-44
1374408-1	1992	Peptide 1-21, generated by cyanogen bromide cleavage of each of two highly purified components of human myelin basic protein, components 1 and 8, gave a series of peaks in the fast atom bombardment mass spectra with m/z 2299, 2327, 2355, 2383, and 2411, indicating additions of 42, 70, 98, 126, and 154 atomic mass units respectively with m/z 2327 and 2355 as the dominant species.	Cyanogen Bromide	27-43	myelin basic protein	Homo sapiens	104-124
1374408-3	1992	These data demonstrated (i) that the N terminus of a myelin basic protein is not simply acetylated but contains C2, C4, C6, C8, and C10 fatty acids with C4 and C6 as the dominant species, (ii) the two components studied (C-1 and C-8) showed different relative amounts of C2 and C8 in particular, and (iii) human myelin basic protein is the first protein to be reported with a complex N terminus consisting of several alkyl carboxylic acid species.	Fatty Acids	136-147	myelin basic protein	Homo sapiens	53-73
1374408-3	1992	These data demonstrated (i) that the N terminus of a myelin basic protein is not simply acetylated but contains C2, C4, C6, C8, and C10 fatty acids with C4 and C6 as the dominant species, (ii) the two components studied (C-1 and C-8) showed different relative amounts of C2 and C8 in particular, and (iii) human myelin basic protein is the first protein to be reported with a complex N terminus consisting of several alkyl carboxylic acid species.	alkyl carboxylic acid	417-438	myelin basic protein	Homo sapiens	53-73
1381412-4	1992	Anti-MBP purified from cerebrospinal fluid of patients with optic neuritis are neutralized by synthetic peptides of human MBP containing overall amino acid residues 61-106 and do not react with synthetic peptides corresponding to residues 1-60 and 107-170.	Peptides	104-112	myelin basic protein	Homo sapiens	5-8
1381412-4	1992	Anti-MBP purified from cerebrospinal fluid of patients with optic neuritis are neutralized by synthetic peptides of human MBP containing overall amino acid residues 61-106 and do not react with synthetic peptides corresponding to residues 1-60 and 107-170.	Peptides	104-112	myelin basic protein	Homo sapiens	122-125
1372178-0	1992	Concerted modulation by myelin basic protein and sulfatide of the activity of phospholipase A2 against phospholipid monolayers.	Phospholipids	103-115	myelin basic protein	Homo sapiens	24-44
1372178-1	1992	The effect of myelin basic protein (MBP) on the activity of phospholipase A2 (PLA2, EC 3.1.1.4) against monolayers of dilauroylphosphatidylcholine (dlPC) or dilauroylphosphatidic acid (dlPA) containing different proportions of sulfatide (Sulf) and galactocerebroside (GalCer) was investigated.	1,2-dilauroylphosphatidylcholine	118-146	myelin basic protein	Homo sapiens	14-34
1372178-1	1992	The effect of myelin basic protein (MBP) on the activity of phospholipase A2 (PLA2, EC 3.1.1.4) against monolayers of dilauroylphosphatidylcholine (dlPC) or dilauroylphosphatidic acid (dlPA) containing different proportions of sulfatide (Sulf) and galactocerebroside (GalCer) was investigated.	1,2-dilauroylphosphatidylcholine	118-146	myelin basic protein	Homo sapiens	36-39
1372178-1	1992	The effect of myelin basic protein (MBP) on the activity of phospholipase A2 (PLA2, EC 3.1.1.4) against monolayers of dilauroylphosphatidylcholine (dlPC) or dilauroylphosphatidic acid (dlPA) containing different proportions of sulfatide (Sulf) and galactocerebroside (GalCer) was investigated.	1,2-dilauroylphosphatidylcholine	148-152	myelin basic protein	Homo sapiens	36-39
1373999-6	1992	Antibodies to MBP were isolated from purified CSF IgG of MS patients with acute relapses by two-step antigen specific (MBP-Sepharose) affinity chromatography.	Sepharose	123-132	myelin basic protein	Homo sapiens	14-17
1373999-6	1992	Antibodies to MBP were isolated from purified CSF IgG of MS patients with acute relapses by two-step antigen specific (MBP-Sepharose) affinity chromatography.	Sepharose	123-132	myelin basic protein	Homo sapiens	119-122
1373999-9	1992	Neutralization of anti-MBP by homologous and heterologous MBP or their synthetic peptides may also be possible in vivo as a potential therapeutic tool.	Peptides	81-89	myelin basic protein	Homo sapiens	23-26
1370254-1	1992	Suppressor T cell (Ts) lines specific for myelin basic protein (MBP)-reactive helper T cell (Th) clones were generated from two patients with multiple sclerosis (MS) following a primary culture of peripheral blood mononuclear cells (PBMC) with MBP and cyclosporine A (CsA).	Cyclosporine	252-266	myelin basic protein	Homo sapiens	42-62
1370347-0	1992	Synthetic copolymer 1 inhibits human T-cell lines specific for myelin basic protein.	copolymer	10-19	myelin basic protein	Homo sapiens	63-83
7566359-0	1995	Myelin basic protein purified on an ion-exchange continuous polymer bed in the presence of ethylene glycol and salt possesses activity against p-nitrophenyl acetate.	Polymers	60-67	myelin basic protein	Homo sapiens	0-20
7566359-0	1995	Myelin basic protein purified on an ion-exchange continuous polymer bed in the presence of ethylene glycol and salt possesses activity against p-nitrophenyl acetate.	Ethylene Glycol	91-106	myelin basic protein	Homo sapiens	0-20
7566359-0	1995	Myelin basic protein purified on an ion-exchange continuous polymer bed in the presence of ethylene glycol and salt possesses activity against p-nitrophenyl acetate.	Salts	111-115	myelin basic protein	Homo sapiens	0-20
7566359-0	1995	Myelin basic protein purified on an ion-exchange continuous polymer bed in the presence of ethylene glycol and salt possesses activity against p-nitrophenyl acetate.	4-nitrophenyl acetate	143-164	myelin basic protein	Homo sapiens	0-20
7566359-1	1995	In this paper we describe a fast and mild method based on the use of a unique cation exchanger and buffers containing ethylene glycol and salt for the purification of the myelin basic protein (MBP; MW 18.5 kDa).	Ethylene Glycol	118-133	myelin basic protein	Homo sapiens	171-191
7566359-1	1995	In this paper we describe a fast and mild method based on the use of a unique cation exchanger and buffers containing ethylene glycol and salt for the purification of the myelin basic protein (MBP; MW 18.5 kDa).	Ethylene Glycol	118-133	myelin basic protein	Homo sapiens	193-196
7566359-1	1995	In this paper we describe a fast and mild method based on the use of a unique cation exchanger and buffers containing ethylene glycol and salt for the purification of the myelin basic protein (MBP; MW 18.5 kDa).	Salts	138-142	myelin basic protein	Homo sapiens	171-191
7566359-1	1995	In this paper we describe a fast and mild method based on the use of a unique cation exchanger and buffers containing ethylene glycol and salt for the purification of the myelin basic protein (MBP; MW 18.5 kDa).	Salts	138-142	myelin basic protein	Homo sapiens	193-196
7566359-2	1995	MBP thus purified hydrolyses catalytically p-nitrophenyl acetate.	4-nitrophenyl acetate	43-64	myelin basic protein	Homo sapiens	0-3
7722326-5	1995	Pretreatment of cells with dibutyryl cAMP or cytochalasin B completely abolished the EDN release induced by MBP and EPO, suggesting that the effects of MBP and EPO are not due to cytotoxic lysis of the cells.	dibutyryl	27-36	myelin basic protein	Homo sapiens	108-111
7722326-5	1995	Pretreatment of cells with dibutyryl cAMP or cytochalasin B completely abolished the EDN release induced by MBP and EPO, suggesting that the effects of MBP and EPO are not due to cytotoxic lysis of the cells.	dibutyryl	27-36	myelin basic protein	Homo sapiens	152-155
7722326-5	1995	Pretreatment of cells with dibutyryl cAMP or cytochalasin B completely abolished the EDN release induced by MBP and EPO, suggesting that the effects of MBP and EPO are not due to cytotoxic lysis of the cells.	Cyclic AMP	37-41	myelin basic protein	Homo sapiens	108-111
7722326-5	1995	Pretreatment of cells with dibutyryl cAMP or cytochalasin B completely abolished the EDN release induced by MBP and EPO, suggesting that the effects of MBP and EPO are not due to cytotoxic lysis of the cells.	Cyclic AMP	37-41	myelin basic protein	Homo sapiens	152-155
7722326-5	1995	Pretreatment of cells with dibutyryl cAMP or cytochalasin B completely abolished the EDN release induced by MBP and EPO, suggesting that the effects of MBP and EPO are not due to cytotoxic lysis of the cells.	Cytochalasin B	45-59	myelin basic protein	Homo sapiens	108-111
7722326-5	1995	Pretreatment of cells with dibutyryl cAMP or cytochalasin B completely abolished the EDN release induced by MBP and EPO, suggesting that the effects of MBP and EPO are not due to cytotoxic lysis of the cells.	Cytochalasin B	45-59	myelin basic protein	Homo sapiens	152-155
7722326-9	1995	The MBP-stimulated production of IL-8 was inhibited by actinomycin D, but not by cyclosporin A.	Dactinomycin	55-68	myelin basic protein	Homo sapiens	4-7
7722326-10	1995	Furthermore, MBP and calcium ionophore ionomycin synergistically induced production of leukotriene C4 from eosinophils.	Leukotriene C4	87-101	myelin basic protein	Homo sapiens	13-16
7722327-11	1995	MAPK activity was determined by measuring 32P phosphorylation of a synthetic peptide containing the recognition site on myelin basic protein for MAPK.	Phosphorus-32	42-45	myelin basic protein	Homo sapiens	120-140
7585040-5	1995	We show, using nuclear magnetic resonance (NMR) and X-ray data, that these terminal GlcNAc residues become accessible for MBP binding.	Acetylglucosamine	84-90	myelin basic protein	Homo sapiens	122-125
7543406-0	1995	Interactions of myelin basic protein with palmitoyllysophosphatidylcholine: characterization of the complexes and conformations of the protein.	We 201	42-74	myelin basic protein	Homo sapiens	16-36
7543406-5	1995	The data suggested that MBP lies primarily near the surface of the micelles, with segments penetrating beyond the interfacial region into the hydrophobic interior, but without any part of the protein being protected against rapid exchange of its amide groups with the aqueous environment.	Amides	246-251	myelin basic protein	Homo sapiens	24-27
7543406-8	1995	Specific residues in myelin basic protein that participated in binding to the micelles were identified from magnetic resonance data on changes in the chemical shifts and intensities of assigned resonances, and line broadening of peaks by fatty acid spin-labels incorporated into the micelles.	Fatty Acids	238-248	myelin basic protein	Homo sapiens	21-41
7527398-2	1994	In cell-free extracts made from gingival fibroblasts treated with platelet-derived growth factor or HepG2 hepatoma cells stimulated with phorbol myristate acetate, MBP and Thr669 kinase were both elevated 4-fold, and ERK1 and ERK2 were tyrosine-phosphorylated.	Tetradecanoylphorbol Acetate	137-162	myelin basic protein	Homo sapiens	164-167
7527398-2	1994	In cell-free extracts made from gingival fibroblasts treated with platelet-derived growth factor or HepG2 hepatoma cells stimulated with phorbol myristate acetate, MBP and Thr669 kinase were both elevated 4-fold, and ERK1 and ERK2 were tyrosine-phosphorylated.	Tyrosine	236-244	myelin basic protein	Homo sapiens	164-167
7527398-4	1994	Ceramide has been proposed as an intracellular mediator of IL-1 action, but C2-ceramide or sphingosine stimulated predominantly MBP-specific kinase activity in fibroblasts and had no effect in HepG2 cells.	N-acetylsphingosine	76-87	myelin basic protein	Homo sapiens	128-131
7527398-4	1994	Ceramide has been proposed as an intracellular mediator of IL-1 action, but C2-ceramide or sphingosine stimulated predominantly MBP-specific kinase activity in fibroblasts and had no effect in HepG2 cells.	Sphingosine	91-102	myelin basic protein	Homo sapiens	128-131
7528922-1	1994	Kinetic rate constants and the equilibrium dissociation constant have been determined for the reaction between an affinity-purified class II major histocompatibility complex molecule IAk and a myelin basic protein analogue peptide, fluorescein-labeled Ac(1-14)A4C15.	Fluorescein	232-243	myelin basic protein	Homo sapiens	193-213
7719475-6	1994	After removal of residual phosphate groups naturally occurring at the C-3 position of the sugar, which interfere with MBP recognition, the mannan was phosphorylated enzymatically at C-6, at which position the OH group is not required for lectin binding.	Sugars	90-95	myelin basic protein	Homo sapiens	118-121
7719475-6	1994	After removal of residual phosphate groups naturally occurring at the C-3 position of the sugar, which interfere with MBP recognition, the mannan was phosphorylated enzymatically at C-6, at which position the OH group is not required for lectin binding.	Mannans	139-145	myelin basic protein	Homo sapiens	118-121
7719475-7	1994	The enzymatically phosphorylated mannan bound to an alumina column was used successfully for MBP separation from rabbit serum.	Mannans	33-39	myelin basic protein	Homo sapiens	93-96
7719475-7	1994	The enzymatically phosphorylated mannan bound to an alumina column was used successfully for MBP separation from rabbit serum.	Aluminum Oxide	52-59	myelin basic protein	Homo sapiens	93-96
7802263-1	1994	This paper describes a mutant of the maltose binding protein (MBP) in which the serine residue at position 337 is replaced by a cysteine residue using site-directed mutagenesis.	Serine	80-86	myelin basic protein	Homo sapiens	37-60
7802263-1	1994	This paper describes a mutant of the maltose binding protein (MBP) in which the serine residue at position 337 is replaced by a cysteine residue using site-directed mutagenesis.	Serine	80-86	myelin basic protein	Homo sapiens	62-65
7802263-1	1994	This paper describes a mutant of the maltose binding protein (MBP) in which the serine residue at position 337 is replaced by a cysteine residue using site-directed mutagenesis.	Cysteine	128-136	myelin basic protein	Homo sapiens	37-60
7802263-1	1994	This paper describes a mutant of the maltose binding protein (MBP) in which the serine residue at position 337 is replaced by a cysteine residue using site-directed mutagenesis.	Cysteine	128-136	myelin basic protein	Homo sapiens	62-65
7802263-2	1994	The mutant MBP has an approximately 2-fold lower affinity for maltose, and the cysteine residue can be modified with 4-[N-(2-(iodoacetoxy)ethyl)-N-methylamino]-7-nitrobenz-2-oxa-1,3-diazole (IANBD) and 6-acryloyl-2-(dimethylamino)-naphthalene (acrylodan).	Maltose	62-69	myelin basic protein	Homo sapiens	11-14
7802263-2	1994	The mutant MBP has an approximately 2-fold lower affinity for maltose, and the cysteine residue can be modified with 4-[N-(2-(iodoacetoxy)ethyl)-N-methylamino]-7-nitrobenz-2-oxa-1,3-diazole (IANBD) and 6-acryloyl-2-(dimethylamino)-naphthalene (acrylodan).	Cysteine	79-87	myelin basic protein	Homo sapiens	11-14
7802263-2	1994	The mutant MBP has an approximately 2-fold lower affinity for maltose, and the cysteine residue can be modified with 4-[N-(2-(iodoacetoxy)ethyl)-N-methylamino]-7-nitrobenz-2-oxa-1,3-diazole (IANBD) and 6-acryloyl-2-(dimethylamino)-naphthalene (acrylodan).	4-[n-(2-(iodoacetoxy)ethyl)-n-methylamino]-7-nitrobenz-2-oxa-1,3-diazole	117-189	myelin basic protein	Homo sapiens	11-14
7802263-2	1994	The mutant MBP has an approximately 2-fold lower affinity for maltose, and the cysteine residue can be modified with 4-[N-(2-(iodoacetoxy)ethyl)-N-methylamino]-7-nitrobenz-2-oxa-1,3-diazole (IANBD) and 6-acryloyl-2-(dimethylamino)-naphthalene (acrylodan).	ianbd	191-196	myelin basic protein	Homo sapiens	11-14
7802263-2	1994	The mutant MBP has an approximately 2-fold lower affinity for maltose, and the cysteine residue can be modified with 4-[N-(2-(iodoacetoxy)ethyl)-N-methylamino]-7-nitrobenz-2-oxa-1,3-diazole (IANBD) and 6-acryloyl-2-(dimethylamino)-naphthalene (acrylodan).	acrylodan	202-242	myelin basic protein	Homo sapiens	11-14
7802263-2	1994	The mutant MBP has an approximately 2-fold lower affinity for maltose, and the cysteine residue can be modified with 4-[N-(2-(iodoacetoxy)ethyl)-N-methylamino]-7-nitrobenz-2-oxa-1,3-diazole (IANBD) and 6-acryloyl-2-(dimethylamino)-naphthalene (acrylodan).	acrylodan	244-253	myelin basic protein	Homo sapiens	11-14
7963274-11	1994	However, the elevation in systolic blood pressure (delta SBP) and mean blood pressure (delta MBP) from basal levels in response to a given dose of phenylephrine were significantly larger (delta SBP:18 +/- 3 vs 26 +/- 3 mmHg, p < .01; and delta MBP 10 +/- 2 vs 15 +/- 3 mmHg, p < .01) after than before training.	Phenylephrine	147-160	myelin basic protein	Homo sapiens	93-96
7963274-11	1994	However, the elevation in systolic blood pressure (delta SBP) and mean blood pressure (delta MBP) from basal levels in response to a given dose of phenylephrine were significantly larger (delta SBP:18 +/- 3 vs 26 +/- 3 mmHg, p < .01; and delta MBP 10 +/- 2 vs 15 +/- 3 mmHg, p < .01) after than before training.	Phenylephrine	147-160	myelin basic protein	Homo sapiens	247-250
7933128-9	1994	The requirements for stable binding were further defined with a series of oligonucleotide probes which spanned the region protected by MBP-Rep78 in DNase I footprinting.	Oligonucleotides	74-89	myelin basic protein	Homo sapiens	135-138
7634089-6	1994	The spatial arrangement of the carbohydrate recognition domains suggest how MBP trimers form the basic recognition unit for branched oligosaccharides on microorganisms.	Carbohydrates	31-43	myelin basic protein	Homo sapiens	76-79
7634089-6	1994	The spatial arrangement of the carbohydrate recognition domains suggest how MBP trimers form the basic recognition unit for branched oligosaccharides on microorganisms.	branched oligosaccharides	124-149	myelin basic protein	Homo sapiens	76-79
7523442-10	1994	The combination of INDO plus LAPGE also inhibited delayed-type hypersensitivity (DTH) reactions to myelin basic protein (MBP), and diminished in vitro lymphocyte responses to mitogens and MBP.	Indomethacin	19-23	myelin basic protein	Homo sapiens	99-119
7523442-10	1994	The combination of INDO plus LAPGE also inhibited delayed-type hypersensitivity (DTH) reactions to myelin basic protein (MBP), and diminished in vitro lymphocyte responses to mitogens and MBP.	lapge	29-34	myelin basic protein	Homo sapiens	99-119
7521366-3	1994	Anion-exchange chromatography on Mono Q demonstrated that LPS treatment resulted in two principal peaks of stimulated MBP kinase activity.	Mono Q	33-39	myelin basic protein	Homo sapiens	118-121
7521366-5	1994	Thus, 1) MBP kinase activity within peak 1 was quantitatively precipitated by anti-MAP kinase Abs, 2) the enzyme effectively phosphorylated a specific peptide substrate, 3) peak 1 contained proteins of subunit size M(r) 42,000 and M(r) 44,000 that reacted specifically with anti-MAP kinase Abs, and that 4) were recognized by anti-phosphotyrosine Abs only after stimulation of cells with LPS.	Phosphotyrosine	331-346	myelin basic protein	Homo sapiens	9-12
8051045-8	1994	This kinase activity required either Mg2+ or Mn2+ for optimal activity, and it phosphorylated myelin basic protein, histone H2B, and also the cytoplasmic domain of the p60 receptor.	magnesium ion	37-41	myelin basic protein	Homo sapiens	94-114
8051045-8	1994	This kinase activity required either Mg2+ or Mn2+ for optimal activity, and it phosphorylated myelin basic protein, histone H2B, and also the cytoplasmic domain of the p60 receptor.	Manganese(2+)	45-49	myelin basic protein	Homo sapiens	94-114
7517973-1	1994	The fine specificity of mAb F28C4 to myelin basic protein (MBP), acetyl residues 1-9, has been compared with the previously described specificity of an encephalitogenic T cell clone, PJR-25.	Cysteine	65-71	myelin basic protein	Homo sapiens	59-62
7517973-5	1994	By using nuclear magnetic resonance, we found that the MBP acetyl peptide 1-9 binds F28C4 in an extended conformation and that the central residues are more tightly bound than the terminal residues, much like the MBP-TCR interaction.	f28c4	84-89	myelin basic protein	Homo sapiens	55-58
8035175-8	1994	Developmental changes in the ATP sensitivity of oligodendroglia occurred in cells expressing galactocerebroside and myelin basic protein.	Adenosine Triphosphate	29-32	myelin basic protein	Homo sapiens	116-136
8021237-4	1994	When ODC purified from ODC-overproducing cells was incubated with the 26 S proteasome and with AZ fused with maltose-binding protein (MBP) in the presence of ATP, ODC was degraded specifically without appreciable breakdown of MBP-AZ.	Adenosine Triphosphate	158-161	myelin basic protein	Homo sapiens	109-132
8021237-4	1994	When ODC purified from ODC-overproducing cells was incubated with the 26 S proteasome and with AZ fused with maltose-binding protein (MBP) in the presence of ATP, ODC was degraded specifically without appreciable breakdown of MBP-AZ.	Adenosine Triphosphate	158-161	myelin basic protein	Homo sapiens	226-229
8058058-6	1994	Partial purification of this Ca(2+)-independent activity has demonstrated phosphorylation of synthetic peptides derived from (a) amino acids 4-14 of myelin basic protein and (b) the pseudosubstrate region of PKC (amino acids 19-31), with substitution of Ala25 with serine.	Peptides	103-111	myelin basic protein	Homo sapiens	149-169
7515885-9	1994	GC kinase immunoprecipitated from transfected COS cells phosphorylated the substrates casein and myelin basic protein.	carbonyl sulfide	46-49	myelin basic protein	Homo sapiens	97-117
7982896-9	1994	A mutant MBP synthesized in COS-1 cells which lacked a sequence comprising 9 amino acid residues at the beginning of the collagen-like domain had no ability to activate the complement, suggesting that this sequence plays an important role in the activation of the complement by human MBP.	carbonyl sulfide	28-31	myelin basic protein	Homo sapiens	9-12
8065531-4	1994	The protein phosphorylation activity in the cytosol from the cell treated with 100 microM forskolin, assayed with myelin basic protein as the acceptor, decreased to 78% and this inhibition was then reversed by the addition of 1-oleoyl-2-acetyl-sn-glycerol (OAG), a membrane-permeable DG, to the assay mixture.	Colforsin	90-99	myelin basic protein	Homo sapiens	114-134
8065531-4	1994	The protein phosphorylation activity in the cytosol from the cell treated with 100 microM forskolin, assayed with myelin basic protein as the acceptor, decreased to 78% and this inhibition was then reversed by the addition of 1-oleoyl-2-acetyl-sn-glycerol (OAG), a membrane-permeable DG, to the assay mixture.	1-oleoyl-2-acetylglycerol	226-255	myelin basic protein	Homo sapiens	114-134
8175758-4	1994	The p15cdk-BP-bound "PSTAIRE signal" is part of a 250-kDa complex distinct from p34cdc2/cyclin B. p15cdk-BP-Sepharose beads retain a kinase phosphorylating HMG I/Y, P1, and myelin basic protein (among 24 substrates tested).	Sepharose	108-117	myelin basic protein	Homo sapiens	173-193
8181480-7	1994	The p72syk had an autophosphorylation activity that was performed by intramolecular catalysis accompanied by a phosphate exchange reaction, and could efficiently phosphorylate tubulin, myelin basic protein and H2B histone.	Phosphates	111-120	myelin basic protein	Homo sapiens	185-205
7514197-3	1994	However, a brief incubation (15 minutes) of two of the four principal eosinophil granule proteins, MBP and EPO, at concentrations of 50 to 200 micrograms/ml, caused a significant concentration-related inhibition of histamine release induced by 30 mumol/L substance P.	Histamine	215-224	myelin basic protein	Homo sapiens	99-102
7514197-4	1994	The concentrations producing 50% inhibition for MBP and EPO on substance P-induced histamine release were 30 micrograms/ml and 100 micrograms/ml, respectively.	Histamine	83-92	myelin basic protein	Homo sapiens	48-51
7512380-0	1994	Acylation of myelin basic protein peptide 1-21 with alkyl carboxylates 2-10 carbons long affects secondary structure and posttranslational modification.	alkyl carboxylates	52-70	myelin basic protein	Homo sapiens	13-33
7512380-0	1994	Acylation of myelin basic protein peptide 1-21 with alkyl carboxylates 2-10 carbons long affects secondary structure and posttranslational modification.	Carbon	76-83	myelin basic protein	Homo sapiens	13-33
9098426-6	1994	Functional studies revealed that M. leprae and M. tuberculosis sonicates bind MBP as strongly as pure mannan.	Mannans	102-108	myelin basic protein	Homo sapiens	78-81
7518008-0	1994	Involvement of protein kinase C in cAMP regulation of myelin basic protein gene expression.	Cyclic AMP	35-39	myelin basic protein	Homo sapiens	54-74
7518008-2	1994	Using stably transfected cell lines containing various deletions of the MBP promoter directing the bacterial chloramphenicol acetyltransferase (CAT) gene we have identified a region of the MBP gene that is inhibitory to stimulation by increased cAMP levels.	Cyclic AMP	245-249	myelin basic protein	Homo sapiens	189-192
7518008-4	1994	The effects on MBP gene expression modulated by TPA and cAMP involve altered DNA-protein interactions in the 5" end of the MBP promoter.	Tetradecanoylphorbol Acetate	48-51	myelin basic protein	Homo sapiens	15-18
7518008-4	1994	The effects on MBP gene expression modulated by TPA and cAMP involve altered DNA-protein interactions in the 5" end of the MBP promoter.	Tetradecanoylphorbol Acetate	48-51	myelin basic protein	Homo sapiens	123-126
7518008-4	1994	The effects on MBP gene expression modulated by TPA and cAMP involve altered DNA-protein interactions in the 5" end of the MBP promoter.	Cyclic AMP	56-60	myelin basic protein	Homo sapiens	15-18
7518008-4	1994	The effects on MBP gene expression modulated by TPA and cAMP involve altered DNA-protein interactions in the 5" end of the MBP promoter.	Cyclic AMP	56-60	myelin basic protein	Homo sapiens	123-126
7507967-2	1994	We report here that NAC completely blocks activation induced death and associated DNA fragmentation of myelin basic protein (MBP) specific T cell hybridomas.	Acetylcysteine	20-23	myelin basic protein	Homo sapiens	103-123
7515696-1	1994	To study the relationship between a bovine serum mannan-binding protein (MBP) and a serum protein reactive with a Ra chemotype strain of Salmonella serovar Typhimurium (Ra-reactive factor, RaRF), both proteins were isolated by use of their affinity for yeast mannan and the Salmonella cells followed by affinity chromatography on mannobiose-Sepharose 4B.	mannobiose	330-340	myelin basic protein	Homo sapiens	49-71
7515696-1	1994	To study the relationship between a bovine serum mannan-binding protein (MBP) and a serum protein reactive with a Ra chemotype strain of Salmonella serovar Typhimurium (Ra-reactive factor, RaRF), both proteins were isolated by use of their affinity for yeast mannan and the Salmonella cells followed by affinity chromatography on mannobiose-Sepharose 4B.	Sepharose	341-350	myelin basic protein	Homo sapiens	49-71
7507208-4	1994	However, the bacterially expressed beta-galactosidase-A6 fusion protein demonstrated both tyrosine and serine phosphorylation in an in vitro kinase assay and phosphorylated exogenous substrates including myelin basic protein specifically on tyrosine residues.	Tyrosine	241-249	myelin basic protein	Homo sapiens	204-224
8288641-7	1994	Treatment of HL-60, but not HL-525, cells with TPA was associated with increased MAP kinase activity as determined by phosphorylation of myelin basic protein and the c-Jun Y peptide.	Tetradecanoylphorbol Acetate	47-50	myelin basic protein	Homo sapiens	137-157
7506931-0	1994	Fragmentation of phospholipid bilayers by myelin basic protein.	Phospholipids	17-29	myelin basic protein	Homo sapiens	42-62
7506931-1	1994	Human myelin basic protein (MBP) is shown to disrupt multilamellar phosphatidylcholine bilayers into small lipoprotein particles in a manner similar to the cytolytic peptide melittin (Dufourc, E. J., Smith, I. C. P., & Dufourcq, J.	Phosphatidylcholines	67-86	myelin basic protein	Homo sapiens	6-26
7506931-1	1994	Human myelin basic protein (MBP) is shown to disrupt multilamellar phosphatidylcholine bilayers into small lipoprotein particles in a manner similar to the cytolytic peptide melittin (Dufourc, E. J., Smith, I. C. P., & Dufourcq, J.	Phosphatidylcholines	67-86	myelin basic protein	Homo sapiens	28-31
7506931-1	1994	Human myelin basic protein (MBP) is shown to disrupt multilamellar phosphatidylcholine bilayers into small lipoprotein particles in a manner similar to the cytolytic peptide melittin (Dufourc, E. J., Smith, I. C. P., & Dufourcq, J.	Adenosine Monophosphate	218-221	myelin basic protein	Homo sapiens	6-26
7506931-1	1994	Human myelin basic protein (MBP) is shown to disrupt multilamellar phosphatidylcholine bilayers into small lipoprotein particles in a manner similar to the cytolytic peptide melittin (Dufourc, E. J., Smith, I. C. P., & Dufourcq, J.	Adenosine Monophosphate	218-221	myelin basic protein	Homo sapiens	28-31
7507496-7	1994	One of the five lines recognized whole human MBP and all five of the lines responded to at least one of the five synthetic peptides corresponding to human MBP residues 8-28, 67-90, 84-102, 87-99 or 130-149.	Peptides	123-131	myelin basic protein	Homo sapiens	155-158
7507225-0	1994	Citrulline-containing myelin basic protein is recognized by T-cell lines derived from multiple sclerosis patients and healthy individuals.	Citrulline	0-10	myelin basic protein	Homo sapiens	22-42
7507225-5	1994	In the present study, we examined a different but abundant charge isomer of MBP, termed MBP-C8, to determine whether it could be recognized by MBP-specific cytotoxic and proliferative T-cell lines (TCL) and whether a T-cell response directed exclusively against citrulline-containing residues of MBP-C8 exists in MS patients and healthy controls.	Citrulline	262-272	myelin basic protein	Homo sapiens	76-79
8253768-3	1993	The profiles of myelin basic protein kinase activity following MonoQ chromatography of extracts obtained from cells incubated with insulin or EGF were almost identical.	Mono Q	63-68	myelin basic protein	Homo sapiens	16-36
7504690-5	1993	The MBP domain most commonly recognized was sequence 80-105 (31% of MS TCL, and 24% of control TCL).	Triclosan	71-74	myelin basic protein	Homo sapiens	4-7
7504690-5	1993	The MBP domain most commonly recognized was sequence 80-105 (31% of MS TCL, and 24% of control TCL).	Triclosan	95-98	myelin basic protein	Homo sapiens	4-7
7504690-11	1993	In these patients 75-87% of the TCL responded to a single, patient-specific cluster of immunodominant T cell epitopes located within a small (20-amino acid) domain of MBP.	Triclosan	32-35	myelin basic protein	Homo sapiens	167-170
7504549-4	1993	The fluorescence maximum in absence of Ca2+ and ATP is 4 times lower than that in their presence although it is reached at the same MBP:actin molar ratio.	Adenosine Triphosphate	48-51	myelin basic protein	Homo sapiens	132-135
7504549-9	1993	A Ca2+/ATP-dependent site located in the amino-terminal region (peptide 1-44) and a Ca2+/ATP-independent one near the carboxyl terminus of the MBP molecule.	Adenosine Triphosphate	89-92	myelin basic protein	Homo sapiens	143-146
8267903-9	1993	RESULTS: Complement activation by HIV envelope glycoproteins was found to be mediated by the binding of MBP to carbohydrates on natural envelope protein produced in virus-infected cells, as well as on glycosylated recombinant envelope proteins produced in insect cells.	Carbohydrates	111-124	myelin basic protein	Homo sapiens	104-107
7515250-3	1993	MBP is a myelin protein which is bound to membrane-phospholipids.	Phospholipids	51-64	myelin basic protein	Homo sapiens	0-3
8366121-10	1993	The autophosphorylation of the 40-kDa protein was positively correlated with MgATP incubation time and an increase in activity toward the S6-21 peptide, histone H4, and myelin basic protein.	Adenosine Triphosphate	77-82	myelin basic protein	Homo sapiens	169-189
7692075-7	1993	Both isoforms of elasmobranch MBP contain 18.5% basic (lysine plus arginine) amino acids, compared with 17.5% in mammalian MBPs comprised of the corresponding exons.	basic (lysine	48-61	myelin basic protein	Homo sapiens	30-33
7692075-7	1993	Both isoforms of elasmobranch MBP contain 18.5% basic (lysine plus arginine) amino acids, compared with 17.5% in mammalian MBPs comprised of the corresponding exons.	arginine) amino acids	67-88	myelin basic protein	Homo sapiens	30-33
7692076-5	1993	One of these which contains citrulline accounts for about 20% of the total MBP.	Citrulline	28-38	myelin basic protein	Homo sapiens	75-78
8352755-3	1993	It seems likely that SP-A, like MBP and conglutinin, may mediate anti-microbial activity through binding to carbohydrates on the microorganisms and collectin receptors on phagocytic cells.	Carbohydrates	108-121	myelin basic protein	Homo sapiens	32-35
8352755-4	1993	We have studied the influence of carbohydrates on the binding of SP-A, MBP and conglutinin to mannan in an enzyme-linked lectin-binding assay.	Carbohydrates	33-46	myelin basic protein	Homo sapiens	71-74
8352755-4	1993	We have studied the influence of carbohydrates on the binding of SP-A, MBP and conglutinin to mannan in an enzyme-linked lectin-binding assay.	Mannans	94-100	myelin basic protein	Homo sapiens	71-74
8352755-8	1993	The best inhibitor of MBP was N-acetylglucosamine.	Acetylglucosamine	30-49	myelin basic protein	Homo sapiens	22-25
8352755-11	1993	For conglutinin, as for MBP, the best inhibitor was N-acetylglucosamine.	Acetylglucosamine	52-71	myelin basic protein	Homo sapiens	24-27
8104891-3	1993	O-2A progenitor cells (A2B5+/GFAP-) and mature oligodendroglia (GC+/MBP+) responded to norepinephrine, glutamate, ATP, and histamine with increased intracellular Ca2+ levels.	Norepinephrine	87-101	myelin basic protein	Homo sapiens	68-71
8104891-3	1993	O-2A progenitor cells (A2B5+/GFAP-) and mature oligodendroglia (GC+/MBP+) responded to norepinephrine, glutamate, ATP, and histamine with increased intracellular Ca2+ levels.	Histamine	123-132	myelin basic protein	Homo sapiens	68-71
7684065-2	1993	Stimulation of expression from the MBP promoter by cyclic AMP is not a rapid response.	Cyclic AMP	51-61	myelin basic protein	Homo sapiens	35-38
7683430-2	1993	Its activity is stimulated > 1000-fold by anionic phospholipids when myelin basic protein or mitogen-activated protein kinase is used as substrate but reduced in the presence of several other substrates.	Phospholipids	53-66	myelin basic protein	Homo sapiens	72-92
8466137-9	1993	One hour after instillation of MBP there was a significant increase in airway responsiveness to inhaled methacholine, whereas control animals exhibited no increase in airway responsiveness.	Methacholine Chloride	104-116	myelin basic protein	Homo sapiens	31-34
8466137-12	1993	As with MBP, airway responsiveness to inhaled methacholine increased 1 h after the instillation of either polycation.	Methacholine Chloride	46-58	myelin basic protein	Homo sapiens	8-11
8473484-1	1993	The effect of human eosinophil major basic protein (MBP) as well as other eosinophil proteins, on binding of [3H]N-methyl-scopolamine ([3H]NMS: 1 x 10(-10) M) to muscarinic M2 receptors in heart membranes and M3 receptors in submandibular gland membranes was studied.	N-Methylscopolamine	113-133	myelin basic protein	Homo sapiens	52-55
8473484-2	1993	MBP inhibited specific binding of [3H]NMS to M2 receptors but not to M3 receptors.	Tritium	35-37	myelin basic protein	Homo sapiens	0-3
8473484-3	1993	MBP also inhibited atropine-induced dissociation of [3H]NMS-receptor complexes in a dose-dependent fashion, demonstrating that the interaction of MBP with the M2 muscarinic receptor is allosteric.	Atropine	19-27	myelin basic protein	Homo sapiens	0-3
8473484-3	1993	MBP also inhibited atropine-induced dissociation of [3H]NMS-receptor complexes in a dose-dependent fashion, demonstrating that the interaction of MBP with the M2 muscarinic receptor is allosteric.	Atropine	19-27	myelin basic protein	Homo sapiens	146-149
8473484-3	1993	MBP also inhibited atropine-induced dissociation of [3H]NMS-receptor complexes in a dose-dependent fashion, demonstrating that the interaction of MBP with the M2 muscarinic receptor is allosteric.	Tritium	53-55	myelin basic protein	Homo sapiens	0-3
8473484-3	1993	MBP also inhibited atropine-induced dissociation of [3H]NMS-receptor complexes in a dose-dependent fashion, demonstrating that the interaction of MBP with the M2 muscarinic receptor is allosteric.	Tritium	53-55	myelin basic protein	Homo sapiens	146-149
8473484-5	1993	Inhibition of [3H]NMS binding by MBP was reversible by treatment with heparin, which binds and neutralizes MBP.	Tritium	15-17	myelin basic protein	Homo sapiens	33-36
8473484-5	1993	Inhibition of [3H]NMS binding by MBP was reversible by treatment with heparin, which binds and neutralizes MBP.	Tritium	15-17	myelin basic protein	Homo sapiens	107-110
8473484-5	1993	Inhibition of [3H]NMS binding by MBP was reversible by treatment with heparin, which binds and neutralizes MBP.	Heparin	70-77	myelin basic protein	Homo sapiens	33-36
8473484-5	1993	Inhibition of [3H]NMS binding by MBP was reversible by treatment with heparin, which binds and neutralizes MBP.	Heparin	70-77	myelin basic protein	Homo sapiens	107-110
7683331-5	1993	Anti-MBP was isolated from purified IgG from brain and spinal cord by MBP-Sepharose affinity chromatography.	Sepharose	74-83	myelin basic protein	Homo sapiens	5-8
8383133-3	1993	By enhancing tyrosine phosphorylation of pp57, diolein increased pp57 kinase activity on myelin basic protein.	Tyrosine	13-21	myelin basic protein	Homo sapiens	89-109
7681451-4	1993	IgG was purified from free protein extracts by protein G Sepharose affinity chromatography and anti-MBP was further isolated from purified IgG by antigen specific (MBP) Sepharose affinity chromatography.	Sepharose	169-178	myelin basic protein	Homo sapiens	100-103
7681451-5	1993	Free and bound anti-MBP were reacted with 20 synthetic peptides of human MBP prepared by the Fmoc method.	Peptides	55-63	myelin basic protein	Homo sapiens	20-23
7681451-5	1993	Free and bound anti-MBP were reacted with 20 synthetic peptides of human MBP prepared by the Fmoc method.	Peptides	55-63	myelin basic protein	Homo sapiens	73-76
7681451-9	1993	This suggests that the most likely epitope of anti-MBP is located between residues 84 and 95 of human MBP just proximal to the tri-proline sequence (99-101).	tri-proline	127-138	myelin basic protein	Homo sapiens	51-54
7681451-9	1993	This suggests that the most likely epitope of anti-MBP is located between residues 84 and 95 of human MBP just proximal to the tri-proline sequence (99-101).	tri-proline	127-138	myelin basic protein	Homo sapiens	102-105
8381095-4	1993	PMA or PE also increased MBP kinase (4- or 2.5-fold, respectively).	Tetradecanoylphorbol Acetate	0-3	myelin basic protein	Homo sapiens	25-28
8381095-4	1993	PMA or PE also increased MBP kinase (4- or 2.5-fold, respectively).	Phenylephrine	7-9	myelin basic protein	Homo sapiens	25-28
8381095-8	1993	Renatured MBP kinase activities following SDS-PAGE in MBP-containing gels and immunoblot analysis showed that peak II was a p42 MAP kinase and peak IV was a p44 MAP kinase.	Sodium Dodecyl Sulfate	42-45	myelin basic protein	Homo sapiens	10-13
7680844-2	1993	Sephadex G75 (superfine) resolved high- and low-molecular-weight contaminants from the 18.5K myelin basic protein.	sephadex	0-12	myelin basic protein	Homo sapiens	93-113
7679637-6	1993	The results demonstrate that Ole2GroPCho inhibits, while PtdSer and cholesterol strongly facilitate MBP-induced membrane aggregation.	Cholesterol	68-79	myelin basic protein	Homo sapiens	100-103
7679637-11	1993	pH-dependent experiments indicate distinct mechanisms to be operative in MBP-induced aggregation of PtdSer and Ole2GroPCho/cholesterol bilayers.	Cholesterol	123-134	myelin basic protein	Homo sapiens	73-76
8416944-1	1993	Human serum (MBP) and human recombinant (rMBP) mannose-binding protein bind to mannose-rich, serum-resistant Salmonella montevideo (SH5770), enhance C3 deposition, and render the organisms serum-sensitive.	Mannose	79-86	myelin basic protein	Homo sapiens	13-16
8273551-3	1993	Maximum PIP was achieved within 30 min after 500 micrograms MBP.	pip	8-11	myelin basic protein	Homo sapiens	60-63
8273551-4	1993	The direct PIP response to 250 micrograms MBP was not different from vehicle.	pip	11-14	myelin basic protein	Homo sapiens	42-45
8273551-6	1993	MBP caused a modest, but significant potentiation of the increase in PIP induced by 1, 3 and 10 micrograms/kg Ach (24, 32 and 28%, respectively, p < 0.02) and to 1 microgram/kg 5-HT (43% p < 0.02).	pip	69-72	myelin basic protein	Homo sapiens	0-3
8273551-6	1993	MBP caused a modest, but significant potentiation of the increase in PIP induced by 1, 3 and 10 micrograms/kg Ach (24, 32 and 28%, respectively, p < 0.02) and to 1 microgram/kg 5-HT (43% p < 0.02).	Acetylcholine	110-113	myelin basic protein	Homo sapiens	0-3
8273551-7	1993	We conclude that MBP at a dose that does not directly affect inspiratory pressure is capable of augmenting the PIP response to IV Ach and 5-HT in vivo.	pip	111-114	myelin basic protein	Homo sapiens	17-20
8273551-7	1993	We conclude that MBP at a dose that does not directly affect inspiratory pressure is capable of augmenting the PIP response to IV Ach and 5-HT in vivo.	Acetylcholine	130-133	myelin basic protein	Homo sapiens	17-20
8299661-8	1993	At the end of amlodipine administration a significant decrease (P < 0.001) in SBP, DBP and MBP from baseline values was observed.	Amlodipine	14-24	myelin basic protein	Homo sapiens	94-97
1477092-1	1992	Mannan-binding protein (MBP) is a lectin which, upon binding to certain carbohydrates, activates the classical pathway of complement without the involvement of antibody or C1q.	Carbohydrates	72-85	myelin basic protein	Homo sapiens	0-22
1304173-4	1992	By substituting carboxylic acids for axial glycines in the translated proteins both mutations would be expected to disrupt the secondary structure of the collagenous triple helix of the 96 kDa MBP subunits.	Carboxylic Acids	16-32	myelin basic protein	Homo sapiens	193-196
1304173-4	1992	By substituting carboxylic acids for axial glycines in the translated proteins both mutations would be expected to disrupt the secondary structure of the collagenous triple helix of the 96 kDa MBP subunits.	Glycine	43-51	myelin basic protein	Homo sapiens	193-196
1460414-3	1992	The human serum MBP fraction was obtained by sequential affinity chromatography on mannan-Sepharose, anti-IgM-Sepharose and anti-MBP-Sepharose in the presence of calcium ions.	Sepharose	90-99	myelin basic protein	Homo sapiens	16-19
1460414-3	1992	The human serum MBP fraction was obtained by sequential affinity chromatography on mannan-Sepharose, anti-IgM-Sepharose and anti-MBP-Sepharose in the presence of calcium ions.	Sepharose	110-119	myelin basic protein	Homo sapiens	16-19
1460414-3	1992	The human serum MBP fraction was obtained by sequential affinity chromatography on mannan-Sepharose, anti-IgM-Sepharose and anti-MBP-Sepharose in the presence of calcium ions.	Sepharose	110-119	myelin basic protein	Homo sapiens	16-19
1460414-3	1992	The human serum MBP fraction was obtained by sequential affinity chromatography on mannan-Sepharose, anti-IgM-Sepharose and anti-MBP-Sepharose in the presence of calcium ions.	Calcium	162-169	myelin basic protein	Homo sapiens	16-19
1460414-5	1992	The C1s-like serine protease, designated MBP-associated serine protease (MASP), was separated from MBP by rechromatography on anti-MBP-Sepharose in the presence of ethylenediaminetetraacetic acid.	Sepharose	135-144	myelin basic protein	Homo sapiens	41-44
1460414-5	1992	The C1s-like serine protease, designated MBP-associated serine protease (MASP), was separated from MBP by rechromatography on anti-MBP-Sepharose in the presence of ethylenediaminetetraacetic acid.	Edetic Acid	164-195	myelin basic protein	Homo sapiens	41-44
1460414-9	1992	Reconstitution experiments using MASP and MBP revealed that combination of the two components restores C4- and C2-activating capacity on mannan.	Mannans	137-143	myelin basic protein	Homo sapiens	42-45
1337288-1	1992	We have used myelin basic protein immobilized in sodium dodecyl sulfate-polyacrylamide gels to identify protein kinases after gel electrophoresis, followed by protein kinase reactions.	Sodium Dodecyl Sulfate	49-71	myelin basic protein	Homo sapiens	13-33
1337288-1	1992	We have used myelin basic protein immobilized in sodium dodecyl sulfate-polyacrylamide gels to identify protein kinases after gel electrophoresis, followed by protein kinase reactions.	polyacrylamide	72-86	myelin basic protein	Homo sapiens	13-33
1384707-0	1992	Modulation by glycosphingolipids of membrane-membrane interactions induced by myelin basic protein and melittin.	Glycosphingolipids	14-32	myelin basic protein	Homo sapiens	78-98
1384707-1	1992	The effect of glycosphingolipids (GSLs) with oligosaccharide chains of different length and charge on membrane-membrane interactions induced by myelin basic protein (MBP) or melittin (Mel) was comparatively investigated with small unilamellar vesicles.	Glycosphingolipids	14-32	myelin basic protein	Homo sapiens	144-164
1384707-1	1992	The effect of glycosphingolipids (GSLs) with oligosaccharide chains of different length and charge on membrane-membrane interactions induced by myelin basic protein (MBP) or melittin (Mel) was comparatively investigated with small unilamellar vesicles.	Glycosphingolipids	14-32	myelin basic protein	Homo sapiens	166-169
1384707-1	1992	The effect of glycosphingolipids (GSLs) with oligosaccharide chains of different length and charge on membrane-membrane interactions induced by myelin basic protein (MBP) or melittin (Mel) was comparatively investigated with small unilamellar vesicles.	Glycosphingolipids	34-38	myelin basic protein	Homo sapiens	144-164
1384707-1	1992	The effect of glycosphingolipids (GSLs) with oligosaccharide chains of different length and charge on membrane-membrane interactions induced by myelin basic protein (MBP) or melittin (Mel) was comparatively investigated with small unilamellar vesicles.	Glycosphingolipids	34-38	myelin basic protein	Homo sapiens	166-169
1384707-1	1992	The effect of glycosphingolipids (GSLs) with oligosaccharide chains of different length and charge on membrane-membrane interactions induced by myelin basic protein (MBP) or melittin (Mel) was comparatively investigated with small unilamellar vesicles.	Oligosaccharides	45-60	myelin basic protein	Homo sapiens	166-169
1384707-5	1992	The Trp region of MBP remains in a rather polar environment when interacting with vesicles; its accessibility to NO3- or acrylamide quenching depends on the type of GSLs in the membrane.	Tryptophan	4-7	myelin basic protein	Homo sapiens	18-21
1384707-5	1992	The Trp region of MBP remains in a rather polar environment when interacting with vesicles; its accessibility to NO3- or acrylamide quenching depends on the type of GSLs in the membrane.	Glycosphingolipids	165-169	myelin basic protein	Homo sapiens	18-21
1295362-5	1992	This human MBP caused modest, but statistically significant, damage to respiratory epithelium (16.4% increase in efflux of 51Cr from guinea-pig tracheal rings) after 3 h of incubation with 10(-4) M concentration, but not with lower concentrations.	Chromium-51	123-127	myelin basic protein	Homo sapiens	11-14
1281644-0	1992	Cerebrospinal fluid myelin basic protein in AIDS dementia complex: relationship to disease progression and zidovudine treatment.	Zidovudine	107-117	myelin basic protein	Homo sapiens	20-40
1395098-6	1992	In the malaria patients an increased level of MBP was maintained during 30 days of treatment with chloroquine.	Chloroquine	98-109	myelin basic protein	Homo sapiens	46-49
1430156-4	1992	High-dose intravenous methylprednisolone (MP) has a beneficial clinical effect; reduces gadolinium enhancement, indicating improvement of BBB integrity; and, in MS patients, decreases intrathecal immunoglobulin synthesis with reduction of cerebrospinal fluid (CSF) myelin basic protein (MBP).	Methylprednisolone	22-40	myelin basic protein	Homo sapiens	265-285
1430156-4	1992	High-dose intravenous methylprednisolone (MP) has a beneficial clinical effect; reduces gadolinium enhancement, indicating improvement of BBB integrity; and, in MS patients, decreases intrathecal immunoglobulin synthesis with reduction of cerebrospinal fluid (CSF) myelin basic protein (MBP).	Methylprednisolone	22-40	myelin basic protein	Homo sapiens	287-290
1430156-4	1992	High-dose intravenous methylprednisolone (MP) has a beneficial clinical effect; reduces gadolinium enhancement, indicating improvement of BBB integrity; and, in MS patients, decreases intrathecal immunoglobulin synthesis with reduction of cerebrospinal fluid (CSF) myelin basic protein (MBP).	Methylprednisolone	42-44	myelin basic protein	Homo sapiens	265-285
1430156-4	1992	High-dose intravenous methylprednisolone (MP) has a beneficial clinical effect; reduces gadolinium enhancement, indicating improvement of BBB integrity; and, in MS patients, decreases intrathecal immunoglobulin synthesis with reduction of cerebrospinal fluid (CSF) myelin basic protein (MBP).	Methylprednisolone	42-44	myelin basic protein	Homo sapiens	287-290
1323434-2	1992	Phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate also increased the MBP kinase activity.	Tetradecanoylphorbol Acetate	0-31	myelin basic protein	Homo sapiens	86-89
1323434-2	1992	Phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate also increased the MBP kinase activity.	Tetradecanoylphorbol Acetate	33-36	myelin basic protein	Homo sapiens	86-89
1323434-2	1992	Phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate also increased the MBP kinase activity.	Phorbol 12,13-Dibutyrate	42-66	myelin basic protein	Homo sapiens	86-89
1323434-3	1992	Downregulation of protein kinase C by prolonged treatment of the cells with phorbol 12,13-dibutyrate markedly attenuated the Ang II- and PMA-induced MBP kinase activation.	Phorbol 12,13-Dibutyrate	76-100	myelin basic protein	Homo sapiens	149-152
1323434-4	1992	The Ang II- and PMA-stimulated MBP kinase activities were resolved almost equally into two distinct fractions on Mono-Q HR5/5 column chromatography (kinase 1 and kinase 2).	Mono-S	113-117	myelin basic protein	Homo sapiens	31-34
1323434-10	1992	These results indicate that in vascular smooth muscle cells Ang II activates two species of MBP/microtubule-associated protein 2 kinases mainly through the protein kinase C-signaling pathway and suggest that tyrosine and serine/threonine phosphorylation may be involved in this process.	Tyrosine	208-216	myelin basic protein	Homo sapiens	92-95
1323434-10	1992	These results indicate that in vascular smooth muscle cells Ang II activates two species of MBP/microtubule-associated protein 2 kinases mainly through the protein kinase C-signaling pathway and suggest that tyrosine and serine/threonine phosphorylation may be involved in this process.	Serine	221-227	myelin basic protein	Homo sapiens	92-95
1323434-10	1992	These results indicate that in vascular smooth muscle cells Ang II activates two species of MBP/microtubule-associated protein 2 kinases mainly through the protein kinase C-signaling pathway and suggest that tyrosine and serine/threonine phosphorylation may be involved in this process.	Threonine	228-237	myelin basic protein	Homo sapiens	92-95
1518847-5	1992	The activation of the Erk-1-encoded myelin basic protein kinase required ATP and correlated directly with the degree of phosphorylation on the same amino acid residues previously shown to be phosphorylated in vivo.	Adenosine Triphosphate	73-76	myelin basic protein	Homo sapiens	36-56
1324436-4	1992	Here we predict the binding site of MBP to its receptor using a "binary docking" technique in which two MBP octapeptide sequences containing mutations that eliminate maltose chemotaxis are independently docked to the receptor.	Maltose	166-173	myelin basic protein	Homo sapiens	36-39
1324436-4	1992	Here we predict the binding site of MBP to its receptor using a "binary docking" technique in which two MBP octapeptide sequences containing mutations that eliminate maltose chemotaxis are independently docked to the receptor.	Maltose	166-173	myelin basic protein	Homo sapiens	104-107
1377710-4	1992	Ga administered in vivo suppressed myelin basic protein (MBP) and purified protein derivative-specific lymphocyte proliferative responses in vitro.	Gallium	0-2	myelin basic protein	Homo sapiens	35-55
1377710-4	1992	Ga administered in vivo suppressed myelin basic protein (MBP) and purified protein derivative-specific lymphocyte proliferative responses in vitro.	Gallium	0-2	myelin basic protein	Homo sapiens	57-60
1377710-5	1992	Addition of Ga to MBP-specific T lymphocyte line cultures at various times after initiation of culture revealed that Ga exerts an effect at an early stage of cellular activation.	Gallium	117-119	myelin basic protein	Homo sapiens	18-21
1377712-2	1992	Eighteen synthetic peptides ranging from 8 to 25 residues and covering the length of h-MBP were prepared by the Fmoc method.	Peptides	19-27	myelin basic protein	Homo sapiens	87-90
1377712-4	1992	Purified anti-MBP was reacted with increasing amounts of h-MBP as well as each of the 18 synthetic peptides in an initial liquid phase assay, and then titers of free anti-MBP in the resulting mixtures were determined by a solid phase radioimmunoassay.	Peptides	99-107	myelin basic protein	Homo sapiens	14-17
1377712-5	1992	Purified anti-MBP was neutralized by h-MBP and 6 of the 18 synthetic peptides used in this study.	Peptides	69-77	myelin basic protein	Homo sapiens	14-17
1500095-1	1992	A common opsonic defect occurring in 7% of the Caucasian population is associated with low serum levels of the lectin mannose binding protein (MBP).	Mannose	118-125	myelin basic protein	Homo sapiens	143-146
1547886-2	1992	Titrations with maltose yield three isosbestic points in the difference spectrum of MBP, consistent with two protein conformations: ligand-free and ligand-bound.	Maltose	16-23	myelin basic protein	Homo sapiens	84-87
1547886-4	1992	These results confirm and extend the results from tritium NMR spectroscopy, namely, that MBP can bind maltodextrin either by the sugar"s anomeric end (high affinity) or by the middle of the maltodextrin chain (low affinity).	Tritium	50-57	myelin basic protein	Homo sapiens	89-92
1547886-4	1992	These results confirm and extend the results from tritium NMR spectroscopy, namely, that MBP can bind maltodextrin either by the sugar"s anomeric end (high affinity) or by the middle of the maltodextrin chain (low affinity).	maltodextrin	102-114	myelin basic protein	Homo sapiens	89-92
1547886-4	1992	These results confirm and extend the results from tritium NMR spectroscopy, namely, that MBP can bind maltodextrin either by the sugar"s anomeric end (high affinity) or by the middle of the maltodextrin chain (low affinity).	Sugars	129-134	myelin basic protein	Homo sapiens	89-92
1547886-4	1992	These results confirm and extend the results from tritium NMR spectroscopy, namely, that MBP can bind maltodextrin either by the sugar"s anomeric end (high affinity) or by the middle of the maltodextrin chain (low affinity).	maltodextrin	190-202	myelin basic protein	Homo sapiens	89-92
1372178-3	1992	The effect of MBP on PLA2 activity depends on the type of phospholipid and on the proportion of MBP at the interface.	Phospholipids	58-70	myelin basic protein	Homo sapiens	14-17
1372178-6	1992	The PLA2 activity against either phospholipid is increased when the mole fraction of MBP exceeds the proportion at which immiscible surface domains are formed.	Phospholipids	33-45	myelin basic protein	Homo sapiens	85-88
1550571-2	1992	A predominant polypeptide of human RaRF with an Mr of 32 kDa (P32) has the same mobility as human MBP on SDS-PAGE gels.	Sodium Dodecyl Sulfate	105-108	myelin basic protein	Homo sapiens	98-101
1371350-6	1992	Results of in vivo competition experiments indicate that this 10-nucleotide motif positively contributes to the overall transcriptional activity obtained from the entire MBP promoter in glial cells.	10-nucleotide	62-75	myelin basic protein	Homo sapiens	170-173
1373062-5	1992	MBP specific T-cell lines were co-cultivated with ET-18-OCH3.	et-18	50-55	myelin basic protein	Homo sapiens	0-3
1370254-1	1992	Suppressor T cell (Ts) lines specific for myelin basic protein (MBP)-reactive helper T cell (Th) clones were generated from two patients with multiple sclerosis (MS) following a primary culture of peripheral blood mononuclear cells (PBMC) with MBP and cyclosporine A (CsA).	Cyclosporine	252-266	myelin basic protein	Homo sapiens	64-67
1370254-1	1992	Suppressor T cell (Ts) lines specific for myelin basic protein (MBP)-reactive helper T cell (Th) clones were generated from two patients with multiple sclerosis (MS) following a primary culture of peripheral blood mononuclear cells (PBMC) with MBP and cyclosporine A (CsA).	Cyclosporine	268-271	myelin basic protein	Homo sapiens	42-62
1370254-1	1992	Suppressor T cell (Ts) lines specific for myelin basic protein (MBP)-reactive helper T cell (Th) clones were generated from two patients with multiple sclerosis (MS) following a primary culture of peripheral blood mononuclear cells (PBMC) with MBP and cyclosporine A (CsA).	Cyclosporine	268-271	myelin basic protein	Homo sapiens	64-67
1370864-2	1992	Before treatment, there was a significant correlation of Gd-DTPA enhancement (seen on 16 of 20 scans) and CSF myelin basic protein (MBP).	Gadolinium DTPA	57-64	myelin basic protein	Homo sapiens	110-130
1370864-2	1992	Before treatment, there was a significant correlation of Gd-DTPA enhancement (seen on 16 of 20 scans) and CSF myelin basic protein (MBP).	Gadolinium DTPA	57-64	myelin basic protein	Homo sapiens	132-135
1721462-0	1991	The ability of myelin basic protein-sensitised leukocytes to adoptively transfer experimental allergic encephalomyelitis following coculture with FK 506, cyclosporine, or prednisolone.	Tacrolimus	146-152	myelin basic protein	Homo sapiens	15-35
1721462-0	1991	The ability of myelin basic protein-sensitised leukocytes to adoptively transfer experimental allergic encephalomyelitis following coculture with FK 506, cyclosporine, or prednisolone.	Cyclosporine	154-166	myelin basic protein	Homo sapiens	15-35
1721462-0	1991	The ability of myelin basic protein-sensitised leukocytes to adoptively transfer experimental allergic encephalomyelitis following coculture with FK 506, cyclosporine, or prednisolone.	Prednisolone	171-183	myelin basic protein	Homo sapiens	15-35
7550760-4	1995	MBP can activate the complement system when bound to carbohydrate.	Carbohydrates	53-65	myelin basic protein	Homo sapiens	0-3
1726091-1	1991	Using purified human brain myelin basic protein (MBP) to raise antiserum in rabbits and to prepare 125I-labelled MBP (chloramine-T method), We have established a high specific, precise and sensitive double-antibody radioimmunoassay for the measurement of human serum MBP.	chloramine-T	118-130	myelin basic protein	Homo sapiens	27-47
1715886-2	1991	Eosinophil granule major basic protein (MBP), a potent toxin for helminths and mammalian cells in vitro, is a single polypeptide chain rich in arginine.	Arginine	143-151	myelin basic protein	Homo sapiens	40-43
1726091-1	1991	Using purified human brain myelin basic protein (MBP) to raise antiserum in rabbits and to prepare 125I-labelled MBP (chloramine-T method), We have established a high specific, precise and sensitive double-antibody radioimmunoassay for the measurement of human serum MBP.	chloramine-T	118-130	myelin basic protein	Homo sapiens	49-52
1711371-0	1991	Physicochemical characterization of dodecylphosphocholine/palmitoyllysophosphatidic acid/myelin basic protein complexes.	dodecylphosphocholine	36-57	myelin basic protein	Homo sapiens	89-109
1907971-1	1991	Synthetic peptides have been used to define the consensus amino acid sequence for substrate recognition by the meiosis-activated myelin basic protein (MBP) kinase (p44mpk), which was purified from maturing sea star oocytes.	Peptides	10-18	myelin basic protein	Homo sapiens	129-149
1907971-1	1991	Synthetic peptides have been used to define the consensus amino acid sequence for substrate recognition by the meiosis-activated myelin basic protein (MBP) kinase (p44mpk), which was purified from maturing sea star oocytes.	Peptides	10-18	myelin basic protein	Homo sapiens	151-154
1723248-5	1991	Myelin basic protein phosphorylated on tyrosine residues by p56lck was successfully used as substrate in the detection of phosphatase activity and vanadate or molybdate were shown to inhibit the phosphatase activity.	Tyrosine	39-47	myelin basic protein	Homo sapiens	0-20
1723248-5	1991	Myelin basic protein phosphorylated on tyrosine residues by p56lck was successfully used as substrate in the detection of phosphatase activity and vanadate or molybdate were shown to inhibit the phosphatase activity.	Vanadates	147-155	myelin basic protein	Homo sapiens	0-20
1723248-5	1991	Myelin basic protein phosphorylated on tyrosine residues by p56lck was successfully used as substrate in the detection of phosphatase activity and vanadate or molybdate were shown to inhibit the phosphatase activity.	molybdate	159-168	myelin basic protein	Homo sapiens	0-20
1713605-3	1991	MBP peptide-pulsed T cell clones specifically stimulated autologous MBP-reactive T cell clones to flux calcium and proliferate.	Calcium	103-110	myelin basic protein	Homo sapiens	0-3
1713605-3	1991	MBP peptide-pulsed T cell clones specifically stimulated autologous MBP-reactive T cell clones to flux calcium and proliferate.	Calcium	103-110	myelin basic protein	Homo sapiens	68-71
1956126-7	1991	2) After training, both heart rates and oxygen uptake during submaximal work loads significantly decreased in group H, but only heart rates significantly decreased in group L. 3) Heart rates with a same oxygen-uptake load during submaximal work seemed to increase in group H, but significantly decreased in group L. 4) The mechanical efficiency during the submaximal work load significantly increased in group H, but not in group L. 5) DBP and MBP during the submaximal work load in group L significantly decreased compared with those before the training.	Oxygen	203-209	myelin basic protein	Homo sapiens	444-447
1711371-0	1991	Physicochemical characterization of dodecylphosphocholine/palmitoyllysophosphatidic acid/myelin basic protein complexes.	palmitoyllysophosphatidic acid	58-88	myelin basic protein	Homo sapiens	89-109
2036421-0	1991	Tritium NMR spectroscopy of ligand binding to maltose-binding protein.	Tritium	0-7	myelin basic protein	Homo sapiens	46-69
1675710-3	1991	The replacement of glycine with an aspartic acid residue disrupts the fifth Gly-Xaa-Yaa repeat in the collagen-like domain of each 32 kD MBP peptide chain and probably prevents the formation of the normal triple helix.	Glycine	19-26	myelin basic protein	Homo sapiens	137-140
1675710-3	1991	The replacement of glycine with an aspartic acid residue disrupts the fifth Gly-Xaa-Yaa repeat in the collagen-like domain of each 32 kD MBP peptide chain and probably prevents the formation of the normal triple helix.	Aspartic Acid	35-48	myelin basic protein	Homo sapiens	137-140
1675710-3	1991	The replacement of glycine with an aspartic acid residue disrupts the fifth Gly-Xaa-Yaa repeat in the collagen-like domain of each 32 kD MBP peptide chain and probably prevents the formation of the normal triple helix.	gly-xaa-yaa	76-87	myelin basic protein	Homo sapiens	137-140
2036421-1	1991	Tritium-labeled alpha- and beta-maltodextrins have been used to study their complexes with maltose-binding protein (MBP), a 40-kDa bacterial protein.	Tritium	0-7	myelin basic protein	Homo sapiens	91-114
2036421-1	1991	Tritium-labeled alpha- and beta-maltodextrins have been used to study their complexes with maltose-binding protein (MBP), a 40-kDa bacterial protein.	Tritium	0-7	myelin basic protein	Homo sapiens	116-119
2036421-1	1991	Tritium-labeled alpha- and beta-maltodextrins have been used to study their complexes with maltose-binding protein (MBP), a 40-kDa bacterial protein.	alpha- and beta-maltodextrins	16-45	myelin basic protein	Homo sapiens	91-114
2036421-1	1991	Tritium-labeled alpha- and beta-maltodextrins have been used to study their complexes with maltose-binding protein (MBP), a 40-kDa bacterial protein.	alpha- and beta-maltodextrins	16-45	myelin basic protein	Homo sapiens	116-119
2036421-4	1991	At 10 degrees C, MBP bound alpha-maltose with 2.7 +/- 0.5-fold higher affinity than beta-maltose, and, for longer maltodextrins, the ratio of affinities (KD beta/KD alpha) was even larger (between 10 and 30).	amylodextrins	27-40	myelin basic protein	Homo sapiens	17-20
2036421-4	1991	At 10 degrees C, MBP bound alpha-maltose with 2.7 +/- 0.5-fold higher affinity than beta-maltose, and, for longer maltodextrins, the ratio of affinities (KD beta/KD alpha) was even larger (between 10 and 30).	maltodextrin	114-127	myelin basic protein	Homo sapiens	17-20
2036421-5	1991	The maximum chemical shift change was 2.2 ppm, suggesting that the reducing end of bound alpha-maltodextrin makes close contact with an aromatic residue in the MBP-binding site.	alpha-maltodextrin	89-107	myelin basic protein	Homo sapiens	160-163
2036421-9	1991	This interpretation also suggests how MBP is able to bind both linear and circular maltodextrins.	maltodextrin	83-96	myelin basic protein	Homo sapiens	38-41
1709185-5	1991	Levels of both MBP and EDN in the second to fifth hour correlated significantly with histamine release in the same sites in the first hour (r = 0.66 and 0.83, respectively).	Histamine	85-94	myelin basic protein	Homo sapiens	15-18
2016285-6	1991	Autophosphorylation of p44mpk to 0.7 mol of phosphate/mol of enzyme was correlated with a modest (approximately 17%) increase in the MBP-phosphorylating activity of the kinase.	Phosphates	44-53	myelin basic protein	Homo sapiens	133-136
2016285-12	1991	The stimulated MBP-phosphorylating activity of p44mpk in cytosols from maturing oocytes was partly stabilized by the presence of the phosphatase inhibitor beta-glycerol phosphate.	beta-glycerophosphoric acid	155-178	myelin basic protein	Homo sapiens	15-18
1716401-2	1991	We have found that zinc acetate is able to inhibit MBP cleavage at concentrations of 1 mM or higher.	Zinc Acetate	19-31	myelin basic protein	Homo sapiens	51-54
1716401-3	1991	Furthermore, the Zn-inhibitable MBP-degrading activity was found to be water-soluble and able to recognize MBP also if this protein was protected by its lipidic environment in the native-like, lipid-bound form.	Zinc	17-19	myelin basic protein	Homo sapiens	32-35
1716401-3	1991	Furthermore, the Zn-inhibitable MBP-degrading activity was found to be water-soluble and able to recognize MBP also if this protein was protected by its lipidic environment in the native-like, lipid-bound form.	Zinc	17-19	myelin basic protein	Homo sapiens	107-110
1716401-3	1991	Furthermore, the Zn-inhibitable MBP-degrading activity was found to be water-soluble and able to recognize MBP also if this protein was protected by its lipidic environment in the native-like, lipid-bound form.	Water	71-76	myelin basic protein	Homo sapiens	32-35
1716402-2	1991	The interaction of some divalent cations with myelin basic protein (MBP) in buffer and in model membranes was studied by using the static fluorescence of the intrinsic tryptophan residue of the protein.	Tryptophan	168-178	myelin basic protein	Homo sapiens	46-66
1716402-2	1991	The interaction of some divalent cations with myelin basic protein (MBP) in buffer and in model membranes was studied by using the static fluorescence of the intrinsic tryptophan residue of the protein.	Tryptophan	168-178	myelin basic protein	Homo sapiens	68-71
1716402-3	1991	Results were indicative of Zn++ ability to bind to MBP.	Zinc	27-31	myelin basic protein	Homo sapiens	51-54
2010556-2	1991	The results of this study show for the first time that installation of major basic protein (MBP) directly into the trachea of primates results in a significant and dose-related increase in airway responsiveness to inhaled methacholine.	Methacholine Chloride	222-234	myelin basic protein	Homo sapiens	71-90
2010556-2	1991	The results of this study show for the first time that installation of major basic protein (MBP) directly into the trachea of primates results in a significant and dose-related increase in airway responsiveness to inhaled methacholine.	Methacholine Chloride	222-234	myelin basic protein	Homo sapiens	92-95
1704014-2	1991	This study examines the antigenic determinants of MBP recognized by human T cells using overlapping, synthetic peptides and T cell lines and clones isolated from four HLA-typed, neurologically normal subjects.	Peptides	111-119	myelin basic protein	Homo sapiens	50-53
1724125-5	1991	We have found that steroids, such as glucocorticoids, stimulate the translation of MBP and PLP mRNAs in cell-free systems and inhibit the translation of CNP mRNA.	Steroids	19-27	myelin basic protein	Homo sapiens	83-86
1724125-7	1991	We have localized a nine nucleotide segment within the 5"-untranslated region of the MBP mRNA that is involved in the action of steroids on translation of this mRNA.	Steroids	128-136	myelin basic protein	Homo sapiens	85-88
1724125-8	1991	We have also determined that the protein synthetic step modulated by the steroids is chain initiation, enhancing the rate at which new ribosomal subunits bind to the MBP mRNAs.	Steroids	73-81	myelin basic protein	Homo sapiens	166-169
1707596-0	1990	The preparation of antibodies reactive against citrulline-containing charge isomers of myelin basic protein but not against the arginine-containing charge isomers.	Citrulline	47-57	myelin basic protein	Homo sapiens	87-107
1709925-2	1991	AlF4- induced a parallel increase in protein kinase activity toward myelin basic protein (MBP) in partially purified cell extracts.	tetrafluoroaluminate	0-4	myelin basic protein	Homo sapiens	68-88
1709925-2	1991	AlF4- induced a parallel increase in protein kinase activity toward myelin basic protein (MBP) in partially purified cell extracts.	tetrafluoroaluminate	0-4	myelin basic protein	Homo sapiens	90-93
1709925-4	1991	Following phenyl-Superose chromatography, a peak of MBP kinase activity eluted at a position characteristic of MAP kinase.	phenyl-superose	10-25	myelin basic protein	Homo sapiens	52-55
1705162-2	1990	Muramyl dipeptide binds to serotonin binding sites on myelin basic protein, LHRH, and MSH-ACTH 4-10.	Acetylmuramyl-Alanyl-Isoglutamine	0-17	myelin basic protein	Homo sapiens	54-74
1705162-2	1990	Muramyl dipeptide binds to serotonin binding sites on myelin basic protein, LHRH, and MSH-ACTH 4-10.	Serotonin	27-36	myelin basic protein	Homo sapiens	54-74
1705162-3	1990	Previously, we reported the existence of structurally similar serotonin binding sites on myelin basic protein, LHRH, and MSH-ACTH 4-10.	Serotonin	62-71	myelin basic protein	Homo sapiens	89-109
1659995-5	1991	In addition, upon serum stimulation, the 42 kDa protein became tyrosine-phosphorylated and enzymatically active towards the substrate myelin basic protein.	Tyrosine	63-71	myelin basic protein	Homo sapiens	134-154
1707596-2	1990	One of the charge isomers C-8, has been shown in our laboratory to contain six citrullinyl residues which replace arginyl residues at selected sites in the MBP.	citrullinyl	79-90	myelin basic protein	Homo sapiens	156-159
1707596-2	1990	One of the charge isomers C-8, has been shown in our laboratory to contain six citrullinyl residues which replace arginyl residues at selected sites in the MBP.	arginyl	114-121	myelin basic protein	Homo sapiens	156-159
1707596-9	1990	This antibody was used to distinguish between a citrulline-containing protein, C-8, a naturally occurring charge isomer of MBP, and a non-citrulline-containing charge isomer of MBP, C-1.	Citrulline	48-58	myelin basic protein	Homo sapiens	123-126
1700788-1	1990	Identification of a steroid modulatory element in the 5"-untranslated region of the myelin basic protein messenger RNA.	Steroids	20-27	myelin basic protein	Homo sapiens	84-104
1706487-3	1990	When the methylation of an arginine residue of MBP was examined in slices of the brainstem and spinal cord, using [3H]methionine as a donor of the methyl groups, no difference was found between Twi and the controls.	Arginine	27-35	myelin basic protein	Homo sapiens	47-50
1700904-3	1990	Since this peptide had the identical sequence to N-terminus of porcine myelin basic protein (pMBP) 1-14, we have designated porcine myelin peptide amide 14 (pMPA14).	Amides	147-152	myelin basic protein	Homo sapiens	71-91
2242612-4	1990	Eosinophil infiltration and degranulation were found in several tissues, especially during the acute phase of the TOS, and serum MBP was significantly elevated during all phases of the disease, suggesting that eosinophils play a role in the pathogenesis of the TOS.	tos	261-264	myelin basic protein	Homo sapiens	129-132
1698931-0	1990	A hydroxyproline-containing protein from shark brain that is related to myelin basic protein.	Hydroxyproline	2-16	myelin basic protein	Homo sapiens	72-92
2170521-7	1990	MBP also stimulated release of superoxide anion (O2-) and lysozyme but not beta-glucuronidase or lactate dehydrogenase.	Superoxides	31-47	myelin basic protein	Homo sapiens	0-3
2170521-7	1990	MBP also stimulated release of superoxide anion (O2-) and lysozyme but not beta-glucuronidase or lactate dehydrogenase.	Superoxides	49-51	myelin basic protein	Homo sapiens	0-3
2170521-8	1990	Additionally, 1.5 microM MBP in combination with FMLP or platelet-activating factor stimulated a synergistic increase in O2- release from cytochalasin B-treated neutrophils.	Superoxides	121-123	myelin basic protein	Homo sapiens	25-28
2170521-8	1990	Additionally, 1.5 microM MBP in combination with FMLP or platelet-activating factor stimulated a synergistic increase in O2- release from cytochalasin B-treated neutrophils.	Cytochalasin B	138-152	myelin basic protein	Homo sapiens	25-28
2170521-9	1990	The degree of synergism with FMLP or platelet-activating factor was inversely related (p less than 0.005) to the level of MBP-induced O2- release.	Superoxides	134-136	myelin basic protein	Homo sapiens	122-125
2212954-2	1990	Both MBP and EPO evoked a dose-dependent nonlytic secretion of platelet 5-hydroxytryptamine in unstirred platelet suspensions even in the presence of 10 microM indomethacin.	Serotonin	72-91	myelin basic protein	Homo sapiens	5-8
2212954-2	1990	Both MBP and EPO evoked a dose-dependent nonlytic secretion of platelet 5-hydroxytryptamine in unstirred platelet suspensions even in the presence of 10 microM indomethacin.	Indomethacin	160-172	myelin basic protein	Homo sapiens	5-8
2212954-4	1990	Secretion by MBP and EPO was inhibited by 1 microM PGE1, but the nature of the inhibition differed from that observed with thrombin.	Alprostadil	51-55	myelin basic protein	Homo sapiens	13-16
2168895-2	1990	Treatment of adipocytes with okadaic acid (a specific inhibitor of type 1 and 2a protein phosphatases) resulted in a rapid 8-10-fold stimulation of cell extract myelin basic protein (MBP) kinase activity (t1/2 = 10 min) and kinase activity toward a synthetic peptide RRLSSLRA (S6 peptide) (t1/2 = 5 min).	Okadaic Acid	29-41	myelin basic protein	Homo sapiens	161-181
1698459-5	1990	Phosphorylation of the exogenous substrate myelin basic protein by DEAE-resolved ovarian kinase showed the variant effector dependence, maximal in the presence of EGTA, phosphatidylserine and 1,2-diolein.	2-diethylaminoethanol	67-71	myelin basic protein	Homo sapiens	43-63
1698459-5	1990	Phosphorylation of the exogenous substrate myelin basic protein by DEAE-resolved ovarian kinase showed the variant effector dependence, maximal in the presence of EGTA, phosphatidylserine and 1,2-diolein.	Egtazic Acid	163-167	myelin basic protein	Homo sapiens	43-63
1698459-5	1990	Phosphorylation of the exogenous substrate myelin basic protein by DEAE-resolved ovarian kinase showed the variant effector dependence, maximal in the presence of EGTA, phosphatidylserine and 1,2-diolein.	diolein	192-203	myelin basic protein	Homo sapiens	43-63
1700423-5	1990	The hMBP epitopes presented by the DR2a heterodimer were mapped to peptides covering amino acid residues 1-44, 76-91, 131-145, or 139-153 and to a region spanning the thrombin-cleaved bond at Arg130-Ala131.	DL-Arginine	192-198	myelin basic protein	Homo sapiens	4-8
2168895-2	1990	Treatment of adipocytes with okadaic acid (a specific inhibitor of type 1 and 2a protein phosphatases) resulted in a rapid 8-10-fold stimulation of cell extract myelin basic protein (MBP) kinase activity (t1/2 = 10 min) and kinase activity toward a synthetic peptide RRLSSLRA (S6 peptide) (t1/2 = 5 min).	Okadaic Acid	29-41	myelin basic protein	Homo sapiens	183-186
2168895-4	1990	MBP kinase activity from cells treated with okadaic acid or insulin was resolved by anion exchange chromatography into two well defined peaks; S6 peptide kinase activity was less well resolved.	Okadaic Acid	44-56	myelin basic protein	Homo sapiens	0-3
2168895-7	1990	Furthermore, a 38-kDa protein which co-eluted with one peak of MBP kinase and a 42-kDa protein which co-eluted with the other peak of MBP kinase were phosphorylated on tyrosine after treatment with okadaic acid.	Tyrosine	168-176	myelin basic protein	Homo sapiens	63-66
2168895-7	1990	Furthermore, a 38-kDa protein which co-eluted with one peak of MBP kinase and a 42-kDa protein which co-eluted with the other peak of MBP kinase were phosphorylated on tyrosine after treatment with okadaic acid.	Tyrosine	168-176	myelin basic protein	Homo sapiens	134-137
2168895-7	1990	Furthermore, a 38-kDa protein which co-eluted with one peak of MBP kinase and a 42-kDa protein which co-eluted with the other peak of MBP kinase were phosphorylated on tyrosine after treatment with okadaic acid.	Okadaic Acid	198-210	myelin basic protein	Homo sapiens	63-66
2168895-7	1990	Furthermore, a 38-kDa protein which co-eluted with one peak of MBP kinase and a 42-kDa protein which co-eluted with the other peak of MBP kinase were phosphorylated on tyrosine after treatment with okadaic acid.	Okadaic Acid	198-210	myelin basic protein	Homo sapiens	134-137
2168895-10	1990	Lastly, the increased tyrosine phosphorylation accompanying the activation of MBP kinases following okadaic acid treatment suggests a role for PP-2a in events that are mediated by tyrosine phosphorylation.	Tyrosine	22-30	myelin basic protein	Homo sapiens	78-81
2168895-10	1990	Lastly, the increased tyrosine phosphorylation accompanying the activation of MBP kinases following okadaic acid treatment suggests a role for PP-2a in events that are mediated by tyrosine phosphorylation.	Okadaic Acid	100-112	myelin basic protein	Homo sapiens	78-81
2168895-10	1990	Lastly, the increased tyrosine phosphorylation accompanying the activation of MBP kinases following okadaic acid treatment suggests a role for PP-2a in events that are mediated by tyrosine phosphorylation.	Tyrosine	180-188	myelin basic protein	Homo sapiens	78-81
1694729-3	1990	T cell recognition sites of the clones on human MBP were identified by using MBP fragments and synthetic peptides.	Peptides	105-113	myelin basic protein	Homo sapiens	48-51
1695239-5	1990	Circular dichroism and Fourier-transform infrared of these MBP peptides in water demonstrated random structure that was partially changed to beta-structure in the shorter peptides.	Water	75-80	myelin basic protein	Homo sapiens	59-62
1694881-6	1990	Two regions of the molecule, MBP peptide 87-106 and MBP peptide 154-172, were recognized by the majority of the polyspecific lines and by four and three of 14 monospecific TCL, respectively.	Triclosan	172-175	myelin basic protein	Homo sapiens	29-32
1694881-6	1990	Two regions of the molecule, MBP peptide 87-106 and MBP peptide 154-172, were recognized by the majority of the polyspecific lines and by four and three of 14 monospecific TCL, respectively.	Triclosan	172-175	myelin basic protein	Homo sapiens	52-55
1694881-10	1990	Several HLA-DR molecules restricted multiple cathepsin D-derived and synthetic MBP peptides, including the regions of peptides 87-106 and 154-172 which, respectively, were recognized in conjunction with four and three HLA-DR types.	Peptides	83-91	myelin basic protein	Homo sapiens	79-82
1692480-0	1990	Interactions of myelin basic protein with mixed dodecylphosphocholine/palmitoyllysophosphatidic acid micelles.	dodecylphosphocholine	48-69	myelin basic protein	Homo sapiens	16-36
2124143-1	1990	The periplasmic maltose binding protein (MBP) is required for the high affinity transport of maltose and maltodextrins and for chemotaxis towards these sugars.	Maltose	16-23	myelin basic protein	Homo sapiens	41-44
2124143-1	1990	The periplasmic maltose binding protein (MBP) is required for the high affinity transport of maltose and maltodextrins and for chemotaxis towards these sugars.	maltodextrin	105-118	myelin basic protein	Homo sapiens	16-39
2124143-1	1990	The periplasmic maltose binding protein (MBP) is required for the high affinity transport of maltose and maltodextrins and for chemotaxis towards these sugars.	maltodextrin	105-118	myelin basic protein	Homo sapiens	41-44
2124143-1	1990	The periplasmic maltose binding protein (MBP) is required for the high affinity transport of maltose and maltodextrins and for chemotaxis towards these sugars.	Sugars	152-158	myelin basic protein	Homo sapiens	16-39
2124143-1	1990	The periplasmic maltose binding protein (MBP) is required for the high affinity transport of maltose and maltodextrins and for chemotaxis towards these sugars.	Sugars	152-158	myelin basic protein	Homo sapiens	41-44
2313094-1	1990	The serum lectin, mannan binding protein (MBP), was isolated in a yield of 40 micrograms/liter from pooled normal human serum by affinity chromatography on mannan-Sepharose, followed by gel-filtration and ion-exchange chromatography and finally by passage down an anti-IgM Sepharose column.	Mannans	18-24	myelin basic protein	Homo sapiens	42-45
2313094-1	1990	The serum lectin, mannan binding protein (MBP), was isolated in a yield of 40 micrograms/liter from pooled normal human serum by affinity chromatography on mannan-Sepharose, followed by gel-filtration and ion-exchange chromatography and finally by passage down an anti-IgM Sepharose column.	Sepharose	163-172	myelin basic protein	Homo sapiens	18-40
2313094-1	1990	The serum lectin, mannan binding protein (MBP), was isolated in a yield of 40 micrograms/liter from pooled normal human serum by affinity chromatography on mannan-Sepharose, followed by gel-filtration and ion-exchange chromatography and finally by passage down an anti-IgM Sepharose column.	Sepharose	163-172	myelin basic protein	Homo sapiens	42-45
1692480-0	1990	Interactions of myelin basic protein with mixed dodecylphosphocholine/palmitoyllysophosphatidic acid micelles.	palmitoyllysophosphatidic acid	70-100	myelin basic protein	Homo sapiens	16-36
2313094-1	1990	The serum lectin, mannan binding protein (MBP), was isolated in a yield of 40 micrograms/liter from pooled normal human serum by affinity chromatography on mannan-Sepharose, followed by gel-filtration and ion-exchange chromatography and finally by passage down an anti-IgM Sepharose column.	Sepharose	273-282	myelin basic protein	Homo sapiens	18-40
1692480-1	1990	The interactions of myelin basic protein and peptides derived from it with detergent micelles of lysophosphatidylglycerol, lysophosphatidylserine, palmitoyllysophosphatidic acid, and sodium lauryl sulfate, and with mixed micelles of the neutral detergent dodecylphosphocholine and the negatively charged detergent palmitoyllysophosphatidic acid, were investigated by 1H NMR spectroscopy and circular dichroic spectropolarimetry.	lysophosphatidylglycerol	97-121	myelin basic protein	Homo sapiens	20-40
2313094-1	1990	The serum lectin, mannan binding protein (MBP), was isolated in a yield of 40 micrograms/liter from pooled normal human serum by affinity chromatography on mannan-Sepharose, followed by gel-filtration and ion-exchange chromatography and finally by passage down an anti-IgM Sepharose column.	Sepharose	273-282	myelin basic protein	Homo sapiens	42-45
2313094-2	1990	A rabbit antiserum was prepared against the purified MBP and an enzyme-linked immunoassay developed that used both the specificity of the polyclonal antibody and the Ca+(+)-dependent carbohydrate binding property of MBP.	Carbohydrates	183-195	myelin basic protein	Homo sapiens	216-219
2313094-4	1990	MBP, after interaction with zymosan, caused efficient activation of a C1r2 125I-C1s2 complex that was prepared by incubation of 125I-C1s2 with serum, from a patient with a complete genetic deficiency of C1q, followed by gel-filtration on Sepharose 6B.	Zymosan	28-35	myelin basic protein	Homo sapiens	0-3
2313094-4	1990	MBP, after interaction with zymosan, caused efficient activation of a C1r2 125I-C1s2 complex that was prepared by incubation of 125I-C1s2 with serum, from a patient with a complete genetic deficiency of C1q, followed by gel-filtration on Sepharose 6B.	Sepharose	238-247	myelin basic protein	Homo sapiens	0-3
2313094-5	1990	The purified MBP is composed of a mixture of trimers, tetramers, pentamers, and hexamers of an approximate 90-kDa structural unit as judged by chromatography, SDS-PAGE and electron microscopy studies.	Sodium Dodecyl Sulfate	159-162	myelin basic protein	Homo sapiens	13-16
1692480-1	1990	The interactions of myelin basic protein and peptides derived from it with detergent micelles of lysophosphatidylglycerol, lysophosphatidylserine, palmitoyllysophosphatidic acid, and sodium lauryl sulfate, and with mixed micelles of the neutral detergent dodecylphosphocholine and the negatively charged detergent palmitoyllysophosphatidic acid, were investigated by 1H NMR spectroscopy and circular dichroic spectropolarimetry.	lysophosphatidylserine	123-145	myelin basic protein	Homo sapiens	20-40
1692480-1	1990	The interactions of myelin basic protein and peptides derived from it with detergent micelles of lysophosphatidylglycerol, lysophosphatidylserine, palmitoyllysophosphatidic acid, and sodium lauryl sulfate, and with mixed micelles of the neutral detergent dodecylphosphocholine and the negatively charged detergent palmitoyllysophosphatidic acid, were investigated by 1H NMR spectroscopy and circular dichroic spectropolarimetry.	palmitoyllysophosphatidic acid	147-177	myelin basic protein	Homo sapiens	20-40
2323577-1	1990	Eosinophil granule major basic protein (MBP), a potent toxin for helminths and mammalian cells, is a single polypeptide rich in arginine.	Arginine	128-136	myelin basic protein	Homo sapiens	40-43
1690134-6	1990	Nonviable glutaraldehyde-fixed MBP-pulsed M phi or membranes derived from MBP-pulsed M phi retain their capacity to block the development of EAE.	Glutaral	10-24	myelin basic protein	Homo sapiens	31-34
1689076-5	1990	Eleven of 258 thioguanine-resistant (hprt-) T cell clones from five of the six MS patients who were tested proliferated in response to human myelin basic protein without prior in vitro exposure to this antigen.	Thioguanine	14-25	myelin basic protein	Homo sapiens	141-161
1692750-0	1990	Myelin basic protein inhibits the calcium response to phytohaemagglutinin in human lymphocytes.	Calcium	34-41	myelin basic protein	Homo sapiens	0-20
1692750-2	1990	Pre-treatment of human lymphocytes with myelin basic protein results in a lower rising of cytosolic concentration of free calcium after stimulation with phytohaemagglutinin.	Calcium	122-129	myelin basic protein	Homo sapiens	40-60
1692750-5	1990	The reduction of the rise of cytosolic calcium induced by phytohaemagglutinin is specific for the myelin basic protein because other proteins like albumin and protamine have no effect.	Calcium	39-46	myelin basic protein	Homo sapiens	98-118
1696816-3	1990	The binding of the fragments to a dansylated synthetic human MBP peptide gly(119)-gly(131), presenting sequence homologies with a viral protein, was measured in buffer and for the first time in reverse micelles of sodium bis(2-ethylhexyl) sulfosuccinate, in isooctane.	Glycine	73-76	myelin basic protein	Homo sapiens	61-64
2268118-11	1990	Analysis of the effect of steroids on cRNAs produced from engineered MBP cDNA constructs has permitted the identification of a nine nucleotide element involved in this steroid modulation within the 5" untranslated region of the MBP mRNA.	Steroids	26-34	myelin basic protein	Homo sapiens	69-72
2268118-11	1990	Analysis of the effect of steroids on cRNAs produced from engineered MBP cDNA constructs has permitted the identification of a nine nucleotide element involved in this steroid modulation within the 5" untranslated region of the MBP mRNA.	Steroids	26-34	myelin basic protein	Homo sapiens	228-231
2268118-11	1990	Analysis of the effect of steroids on cRNAs produced from engineered MBP cDNA constructs has permitted the identification of a nine nucleotide element involved in this steroid modulation within the 5" untranslated region of the MBP mRNA.	Steroids	26-33	myelin basic protein	Homo sapiens	69-72
2268118-11	1990	Analysis of the effect of steroids on cRNAs produced from engineered MBP cDNA constructs has permitted the identification of a nine nucleotide element involved in this steroid modulation within the 5" untranslated region of the MBP mRNA.	Steroids	26-33	myelin basic protein	Homo sapiens	228-231
1688880-1	1990	When experimental autoimmune encephalomyelitis (EAE) is induced by adoptive transfer of myelin basic protein (MBP)-specific lymphocytes the splenic noradrenergic and adrenocortical responses mirror in most respects those that occur following sensitization with spinal cord and Freund"s adjuvant (CFA), despite the absence of the primary immune challenge.	3-chloro-4-fluoroaniline	296-299	myelin basic protein	Homo sapiens	88-108
1688880-1	1990	When experimental autoimmune encephalomyelitis (EAE) is induced by adoptive transfer of myelin basic protein (MBP)-specific lymphocytes the splenic noradrenergic and adrenocortical responses mirror in most respects those that occur following sensitization with spinal cord and Freund"s adjuvant (CFA), despite the absence of the primary immune challenge.	3-chloro-4-fluoroaniline	296-299	myelin basic protein	Homo sapiens	110-113
1696816-3	1990	The binding of the fragments to a dansylated synthetic human MBP peptide gly(119)-gly(131), presenting sequence homologies with a viral protein, was measured in buffer and for the first time in reverse micelles of sodium bis(2-ethylhexyl) sulfosuccinate, in isooctane.	Glycine	82-85	myelin basic protein	Homo sapiens	61-64
1696816-3	1990	The binding of the fragments to a dansylated synthetic human MBP peptide gly(119)-gly(131), presenting sequence homologies with a viral protein, was measured in buffer and for the first time in reverse micelles of sodium bis(2-ethylhexyl) sulfosuccinate, in isooctane.	Dioctyl Sulfosuccinic Acid	214-253	myelin basic protein	Homo sapiens	61-64
1696816-3	1990	The binding of the fragments to a dansylated synthetic human MBP peptide gly(119)-gly(131), presenting sequence homologies with a viral protein, was measured in buffer and for the first time in reverse micelles of sodium bis(2-ethylhexyl) sulfosuccinate, in isooctane.	2,2,4-trimethylpentane	258-267	myelin basic protein	Homo sapiens	61-64
1689270-0	1990	Repetitive DNA (TGGA)n 5" to the human myelin basic protein gene: a new form of oligonucleotide repetitive sequence showing length polymorphism.	Oligonucleotides	80-95	myelin basic protein	Homo sapiens	39-59
1689270-3	1990	This sequence is located from 1082 to 2075 bp upstream of the MBP initiator methionine.	Methionine	76-86	myelin basic protein	Homo sapiens	62-65
20504594-3	1990	A second radioimmunoassay was produced with high sensitivity and specificity for myelin basic protein peptides with a carboxyl terminus at phenylalanine 89.	Phenylalanine	139-152	myelin basic protein	Homo sapiens	81-101
33807720-6	2021	5-HT inhibits OPC migration and proliferation and increases OL phenotypic markers myelin basic protein (MBP) and Olig-2 via protein kinase C (PKC) activation since the inhibitor of PKC, bis-indolyl-maleimide (BIM), counteracts 5-HT effects.	Serotonin	0-4	myelin basic protein	Homo sapiens	82-102
33807720-6	2021	5-HT inhibits OPC migration and proliferation and increases OL phenotypic markers myelin basic protein (MBP) and Olig-2 via protein kinase C (PKC) activation since the inhibitor of PKC, bis-indolyl-maleimide (BIM), counteracts 5-HT effects.	Serotonin	0-4	myelin basic protein	Homo sapiens	104-107
33807720-6	2021	5-HT inhibits OPC migration and proliferation and increases OL phenotypic markers myelin basic protein (MBP) and Olig-2 via protein kinase C (PKC) activation since the inhibitor of PKC, bis-indolyl-maleimide (BIM), counteracts 5-HT effects.	bisindolylmaleimide	186-207	myelin basic protein	Homo sapiens	82-102
26246181-2	2016	The pharmacological function of MBP can be mimicked by poly-L-arginine (PLA), however, the potential signaling mechanisms of LPS-PLA-induced release of the inflammatory cytokines interleukin (IL)-6 and IL-8 remain unclear.	polyarginine	55-70	myelin basic protein	Homo sapiens	32-35
1739138-3	1992	The authors used an indirect immunofluorescent technique to localize eosinophil granule major basic protein (MBP) in formalin-fixed, paraffin-embedded tissue specimens from 50 patients.	Formaldehyde	117-125	myelin basic protein	Homo sapiens	109-112
1739138-3	1992	The authors used an indirect immunofluorescent technique to localize eosinophil granule major basic protein (MBP) in formalin-fixed, paraffin-embedded tissue specimens from 50 patients.	Paraffin	133-141	myelin basic protein	Homo sapiens	109-112
34866692-6	2021	Supplementary citicoline treatment provided significant reductions of the levels of GFAP (33%, P = 0.034), NF-L (27%, P = 0.019), and MBP (32%, P = 0.018), as compared to the initial values, while there were no marked changes in the studied parameters in the control group.	Cytidine Diphosphate Choline	14-24	myelin basic protein	Homo sapiens	134-137
34562586-5	2022	Combination small ubiquitin-related modifier protein (SUMO) and maltose-binding protein (MBP) was employed to achieve the soluble expression of dHU-wPU.	1,3-Dicyclohexylurea	144-147	myelin basic protein	Homo sapiens	64-87
34562586-5	2022	Combination small ubiquitin-related modifier protein (SUMO) and maltose-binding protein (MBP) was employed to achieve the soluble expression of dHU-wPU.	1,3-Dicyclohexylurea	144-147	myelin basic protein	Homo sapiens	89-92
34899263-4	2021	In addition, CA is associated with neurodegeneration as indicated by colocalization of degraded myelin basic protein (dMBP) with periodic acid-Schiff (PAS), a CA marker.	Periodic Acid	129-142	myelin basic protein	Homo sapiens	96-116
34827627-3	2021	Here we used combination of formaldehyde-induced cross-linking followed by immunoprecipitation and liquid chromatography-tandem mass spectrometry (LC-MS/MS) to elucidate the interaction network of MBP in mammalian cells and provide the list of potential MBP interacting proteins.	Formaldehyde	28-40	myelin basic protein	Homo sapiens	197-200
34827627-3	2021	Here we used combination of formaldehyde-induced cross-linking followed by immunoprecipitation and liquid chromatography-tandem mass spectrometry (LC-MS/MS) to elucidate the interaction network of MBP in mammalian cells and provide the list of potential MBP interacting proteins.	Formaldehyde	28-40	myelin basic protein	Homo sapiens	254-257
34298044-3	2021	Commercially available amylose matrix for the affinity purification of MBP fusion proteins has two main issues: (i) low (micromolar) affinity and (ii) the limited number of uses due to the cleavage of polysaccharide matrix by the amylases, present in the crude cell extract.	Amylose	23-30	myelin basic protein	Homo sapiens	71-74
34683173-7	2021	The results suggest that a relationship exists between the effectiveness of the treatment with GA and the presence of polymorphisms in the following genes: CD86, CLEC16A, CTSS, EOMES, MBP, FAS, TRBC1, IL1R1, IL12RB2, IL22RA2, PTPRT, PVT1, ALOX5AP, MAGI2, ZAK, RFPL3, UVRAG, SLC1A4, and HLA-DRB1*1501.	Glatiramer Acetate	95-97	myelin basic protein	Homo sapiens	184-187
34623258-6	2021	These experiments reveal differences in heterogeneity in the apo and holo conformational states of MBP and produce accurate quantification of the distributions among apo and holo conformational states at subsaturating maltose concentrations.	Maltose	218-225	myelin basic protein	Homo sapiens	99-102
34630611-8	2021	After treatment, the levels of NSE, MBP, TNF-alpha, and IL-6 in the two groups decreased, and the levels of BDNF increased, and the LEV group changed significantly compared with the VPA group (P < 0.05).	Valproic Acid	182-185	myelin basic protein	Homo sapiens	36-39
34298044-3	2021	Commercially available amylose matrix for the affinity purification of MBP fusion proteins has two main issues: (i) low (micromolar) affinity and (ii) the limited number of uses due to the cleavage of polysaccharide matrix by the amylases, present in the crude cell extract.	Polysaccharides	201-215	myelin basic protein	Homo sapiens	71-74
34110176-0	2021	Assessment of the Oral Delivery of a Myelin Basic Protein Gene Promoter with Antiapoptotic bcl-xL (pMBP-bcl-xL) DNA by Cyclic Peptide Nanotubes with Two Aspect Ratios and Its Biodistribution in the Brain and Spinal Cord.	Peptides, Cyclic	119-133	myelin basic protein	Homo sapiens	37-57
34457311-0	2021	Myelin basic protein expression in thymoma after methylprednisolone administration for multiple sclerosis.	Methylprednisolone	49-67	myelin basic protein	Homo sapiens	0-20
35202838-4	2022	The immobilized anti-MBP were further conjugated with a secondary antibody labelled with horseradish peroxidase (HRP-anti-hIgG) and amperometric transduction was performed by adding hydrogen peroxide and using hydroquinone (HQ) as redox mediator.	Hydrogen Peroxide	182-199	myelin basic protein	Homo sapiens	21-24
35202838-4	2022	The immobilized anti-MBP were further conjugated with a secondary antibody labelled with horseradish peroxidase (HRP-anti-hIgG) and amperometric transduction was performed by adding hydrogen peroxide and using hydroquinone (HQ) as redox mediator.	hydroquinone	210-222	myelin basic protein	Homo sapiens	21-24
35521963-1	2022	The naturally occurring imino acid azetidine-2-carboxylic acid (Aze) is consumed by humans and can be misincorporated in place of proline in myelin basic protein (MBP) in vitro.	Imino Acids	24-34	myelin basic protein	Homo sapiens	141-161
35605982-6	2022	For further validation, we also prepared a maltose-binding protein-linked IgG1-Fc fragment (MBP-Fc).	Maltose	43-50	myelin basic protein	Homo sapiens	92-95
35521963-1	2022	The naturally occurring imino acid azetidine-2-carboxylic acid (Aze) is consumed by humans and can be misincorporated in place of proline in myelin basic protein (MBP) in vitro.	Imino Acids	24-34	myelin basic protein	Homo sapiens	163-166
35521963-1	2022	The naturally occurring imino acid azetidine-2-carboxylic acid (Aze) is consumed by humans and can be misincorporated in place of proline in myelin basic protein (MBP) in vitro.	Azetidinecarboxylic Acid	35-62	myelin basic protein	Homo sapiens	141-161
35521963-1	2022	The naturally occurring imino acid azetidine-2-carboxylic acid (Aze) is consumed by humans and can be misincorporated in place of proline in myelin basic protein (MBP) in vitro.	Azetidinecarboxylic Acid	35-62	myelin basic protein	Homo sapiens	163-166
35388392-1	2022	A metal-binding peptide appending cholic acid, Chol-MBP, formed bicelles by mixing with 1,2-dipalmitoyl-sn-glycero-3-phosphorylcholine (DPPC).	Metals	2-7	myelin basic protein	Homo sapiens	52-55
35521963-1	2022	The naturally occurring imino acid azetidine-2-carboxylic acid (Aze) is consumed by humans and can be misincorporated in place of proline in myelin basic protein (MBP) in vitro.	Azetidinecarboxylic Acid	64-67	myelin basic protein	Homo sapiens	141-161
35521963-1	2022	The naturally occurring imino acid azetidine-2-carboxylic acid (Aze) is consumed by humans and can be misincorporated in place of proline in myelin basic protein (MBP) in vitro.	Azetidinecarboxylic Acid	64-67	myelin basic protein	Homo sapiens	163-166
35521963-1	2022	The naturally occurring imino acid azetidine-2-carboxylic acid (Aze) is consumed by humans and can be misincorporated in place of proline in myelin basic protein (MBP) in vitro.	Proline	130-137	myelin basic protein	Homo sapiens	141-161
35521963-1	2022	The naturally occurring imino acid azetidine-2-carboxylic acid (Aze) is consumed by humans and can be misincorporated in place of proline in myelin basic protein (MBP) in vitro.	Proline	130-137	myelin basic protein	Homo sapiens	163-166
35568196-8	2022	We show that purified rASC spontaneously precipitated and was functional, whereas the maltose binding protein-ASC (MBP-ASC) fusion to ASC (promoting enhanced solubility) was inactive until induced to insolubility by binding to amylose beads.	Amylose	227-234	myelin basic protein	Homo sapiens	115-118
35491432-6	2022	Patients with high tumor mutational burden (TMB, >=5 mutations/Mbp) had a better CBR (70.8% vs. 22.2%), longer OS (14.32 vs. 9.64 months), and a trend towards longer PFS (7.03 vs. 4.06 months).	1,2,4,5-tetramethoxybenzene	44-47	myelin basic protein	Homo sapiens	63-66
35388392-1	2022	A metal-binding peptide appending cholic acid, Chol-MBP, formed bicelles by mixing with 1,2-dipalmitoyl-sn-glycero-3-phosphorylcholine (DPPC).	Cholic Acid	34-45	myelin basic protein	Homo sapiens	52-55
35388392-1	2022	A metal-binding peptide appending cholic acid, Chol-MBP, formed bicelles by mixing with 1,2-dipalmitoyl-sn-glycero-3-phosphorylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	88-134	myelin basic protein	Homo sapiens	52-55
35388392-1	2022	A metal-binding peptide appending cholic acid, Chol-MBP, formed bicelles by mixing with 1,2-dipalmitoyl-sn-glycero-3-phosphorylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	136-140	myelin basic protein	Homo sapiens	52-55
35388392-2	2022	Coordination of Chol-MBP with Cu2+ stabilized DPPC bicelles against dilution and contamination of serum proteins, enabling extended blood circulation.	1,2-Dipalmitoylphosphatidylcholine	46-50	myelin basic protein	Homo sapiens	21-24
35007660-6	2022	Interestingly, N-glycosylation of the CGRP receptor ECD was predicted to prevent MBP docking to the mutated peptide ligands.	Nitrogen	15-16	myelin basic protein	Homo sapiens	81-84
35089601-5	2022	4-methyl benzophenone (4-MBP) and 1-hydroxy-cyclohexyl-phenyl-ketone (1-HCPK) were found in the magazine cover.	4-methylbenzophenone	0-21	myelin basic protein	Homo sapiens	25-28
35007660-7	2022	I found that the N-glycosylation of CLR ECD N123 was the most critical for inhibiting MBP interaction with the mutated peptide ligands.	Nitrogen	17-18	myelin basic protein	Homo sapiens	86-89
35007660-7	2022	I found that the N-glycosylation of CLR ECD N123 was the most critical for inhibiting MBP interaction with the mutated peptide ligands.	4'-bromo-3'-nitropropiophenone	44-48	myelin basic protein	Homo sapiens	86-89
35084527-2	2022	In order to get more detailed mechanisms of this interaction, the MBP of different concentrations interacting with plasma membrane (POPC/POPE/POPS/Cholesterol (Chol)) model to form bionic membrane was studied by atomic force microscopy (AFM) and Langmuir monolayer technology.	Cholesterol	147-158	myelin basic protein	Homo sapiens	66-69
34600402-4	2022	For this purpose, maltose binding protein harbouring the aD region (MBP-aD) was synthesized as a bioreceptor and immobilized on the screen-printed carbon electrode (SPCE).	Maltose	18-25	myelin basic protein	Homo sapiens	68-71
34600402-4	2022	For this purpose, maltose binding protein harbouring the aD region (MBP-aD) was synthesized as a bioreceptor and immobilized on the screen-printed carbon electrode (SPCE).	Carbon	147-153	myelin basic protein	Homo sapiens	68-71
34600402-5	2022	Following that, PAMAM-Au was deposited on MBP-aD, forming the "gate" and was used as a monitoring agent.	pamam-au	16-24	myelin basic protein	Homo sapiens	42-45
34600402-6	2022	Under optimal conditions, the high specificity of anti-HBsAg antibody towards MBP-aD displaced PAMAM-Au causing the decrement of anodic peak in differential pulse voltammetry (DPV) analysis.	pamam-au	95-103	myelin basic protein	Homo sapiens	78-81
35256958-3	2022	Here, an innovative platform, perfluorooctyl bromide (PFOB) nanoemulsions holding MnO2 nanoparticles (MBP), was developed to orchestrate cancer immunotherapy, serving as a theranostic nanoagent for MRI/CT dual-modality imaging and advanced ICD.	perflubron	30-52	myelin basic protein	Homo sapiens	102-105
35256958-3	2022	Here, an innovative platform, perfluorooctyl bromide (PFOB) nanoemulsions holding MnO2 nanoparticles (MBP), was developed to orchestrate cancer immunotherapy, serving as a theranostic nanoagent for MRI/CT dual-modality imaging and advanced ICD.	perflubron	54-58	myelin basic protein	Homo sapiens	102-105
35256958-3	2022	Here, an innovative platform, perfluorooctyl bromide (PFOB) nanoemulsions holding MnO2 nanoparticles (MBP), was developed to orchestrate cancer immunotherapy, serving as a theranostic nanoagent for MRI/CT dual-modality imaging and advanced ICD.	manganese dioxide	82-86	myelin basic protein	Homo sapiens	102-105
35256958-4	2022	By simultaneously depleting the GSH and eliciting the ICD effect via high-intensity focused ultrasound (HIFU) therapy, the MBP nanomedicine can regulate the tumor immune microenvironment by inducing maturation of dendritic cells (DCs) and facilitating the activation of CD8+ and CD4+ T cells.	Glutathione	32-35	myelin basic protein	Homo sapiens	123-126
35084527-2	2022	In order to get more detailed mechanisms of this interaction, the MBP of different concentrations interacting with plasma membrane (POPC/POPE/POPS/Cholesterol (Chol)) model to form bionic membrane was studied by atomic force microscopy (AFM) and Langmuir monolayer technology.	chol	160-164	myelin basic protein	Homo sapiens	66-69
35082605-6	2021	Using the Oli-neuM cell line, we show that GSA-10 promotes Gli2 upregulation, MBP and MAL/OPALIN expression via Smo/AMP-activated Protein Kinase (AMPK) signaling, and efficiently increases the number of axonal contact/ensheathment for each oligodendroglial cell.	GSA-10	43-49	myelin basic protein	Homo sapiens	78-81
2592561-1	1989	The human mannose-binding protein (MBP) is a multimeric serum protein that is divided into three domains, a cysteine-rich NH2-terminal domain that stabilizes the collagen alpha helix of the second domain and a third COOH-terminal carbohydrate recognition domain.	Cysteine	108-116	myelin basic protein	Homo sapiens	10-33
35585312-2	2022	Nickel-charged affinity resins and amylose resins are two commonly used matrices for the isolation of proteins with histidine tag (6x His-tag) and maltose binding protein (MBP) tag, respectively.	Nickel	0-6	myelin basic protein	Homo sapiens	147-170
35585312-2	2022	Nickel-charged affinity resins and amylose resins are two commonly used matrices for the isolation of proteins with histidine tag (6x His-tag) and maltose binding protein (MBP) tag, respectively.	Nickel	0-6	myelin basic protein	Homo sapiens	172-175
35585312-2	2022	Nickel-charged affinity resins and amylose resins are two commonly used matrices for the isolation of proteins with histidine tag (6x His-tag) and maltose binding protein (MBP) tag, respectively.	Amylose	35-42	myelin basic protein	Homo sapiens	147-170
35585312-2	2022	Nickel-charged affinity resins and amylose resins are two commonly used matrices for the isolation of proteins with histidine tag (6x His-tag) and maltose binding protein (MBP) tag, respectively.	Amylose	35-42	myelin basic protein	Homo sapiens	172-175
34293355-5	2022	The differential hypomethylation of the top-ranked cg24700313 cluster in the golli-mbp locus was validated by pyrosequencing in an independent cohort of 224 children with AD and 44 control subjects.	cg24700313	51-61	myelin basic protein	Homo sapiens	77-86
2592561-1	1989	The human mannose-binding protein (MBP) is a multimeric serum protein that is divided into three domains, a cysteine-rich NH2-terminal domain that stabilizes the collagen alpha helix of the second domain and a third COOH-terminal carbohydrate recognition domain.	Cysteine	108-116	myelin basic protein	Homo sapiens	35-38
2592561-1	1989	The human mannose-binding protein (MBP) is a multimeric serum protein that is divided into three domains, a cysteine-rich NH2-terminal domain that stabilizes the collagen alpha helix of the second domain and a third COOH-terminal carbohydrate recognition domain.	Carbohydrates	230-242	myelin basic protein	Homo sapiens	10-33
2592561-1	1989	The human mannose-binding protein (MBP) is a multimeric serum protein that is divided into three domains, a cysteine-rich NH2-terminal domain that stabilizes the collagen alpha helix of the second domain and a third COOH-terminal carbohydrate recognition domain.	Carbohydrates	230-242	myelin basic protein	Homo sapiens	35-38
2592561-2	1989	Previous studies have shown that both native and recombinant human MBP bind to wild-type virulent Salmonella montevideo that expresses a mannose-rich lipopolysaccharide.	mannose-rich lipopolysaccharide	137-168	myelin basic protein	Homo sapiens	67-70
2479764-1	1989	Galactocerebroside:antibody interactions signal changes in cytoskeleton and myelin basic protein.	galactocerebroside	0-18	myelin basic protein	Homo sapiens	76-96
2573758-2	1989	In this study, the presence of the defect was linked with low levels of mannan-binding protein (MBP), a calcium-dependent serum lectin.	Calcium	104-111	myelin basic protein	Homo sapiens	96-99
2573758-3	1989	Purified MBP corrected the defect in a dose-dependent way in an in-vitro assay measuring the deposition of complement moieties on a mannan-coated surface.	Mannans	132-138	myelin basic protein	Homo sapiens	9-12
2480186-0	1989	Interaction and fusion of unilamellar vesicles containing cerebrosides and sulfatides induced by myelin basic protein.	Cerebrosides	58-70	myelin basic protein	Homo sapiens	97-117
2480186-0	1989	Interaction and fusion of unilamellar vesicles containing cerebrosides and sulfatides induced by myelin basic protein.	Sulfoglycosphingolipids	75-85	myelin basic protein	Homo sapiens	97-117
2480186-3	1989	The apposition of membranes rapidly induced by myelin basic protein is enhanced by sulfatide but reduced by galactocerebroside compared to vesicles of egg phosphatidylcholine alone.	Sulfoglycosphingolipids	83-92	myelin basic protein	Homo sapiens	47-67
2480186-3	1989	The apposition of membranes rapidly induced by myelin basic protein is enhanced by sulfatide but reduced by galactocerebroside compared to vesicles of egg phosphatidylcholine alone.	galactocerebroside	108-126	myelin basic protein	Homo sapiens	47-67
2480186-3	1989	The apposition of membranes rapidly induced by myelin basic protein is enhanced by sulfatide but reduced by galactocerebroside compared to vesicles of egg phosphatidylcholine alone.	Phosphatidylcholines	155-174	myelin basic protein	Homo sapiens	47-67
2480186-4	1989	On the other hand, the presence of either glycosphingolipid in the membrane interferes with the induction by myelin basic protein of lipid bilayer merging, subsequent fusion and changes of the membrane permeability.	Glycosphingolipids	42-59	myelin basic protein	Homo sapiens	109-129
2480186-5	1989	Our results support an important modulation by sulfatide and galactocerebroside on the interactions among membranes induced by myelin basic protein, depending on the relative proportions of the glycosphingolipids and phosphatidylcholine.	Sulfoglycosphingolipids	47-56	myelin basic protein	Homo sapiens	127-147
2480186-5	1989	Our results support an important modulation by sulfatide and galactocerebroside on the interactions among membranes induced by myelin basic protein, depending on the relative proportions of the glycosphingolipids and phosphatidylcholine.	galactocerebroside	61-79	myelin basic protein	Homo sapiens	127-147
2480186-5	1989	Our results support an important modulation by sulfatide and galactocerebroside on the interactions among membranes induced by myelin basic protein, depending on the relative proportions of the glycosphingolipids and phosphatidylcholine.	Glycosphingolipids	194-212	myelin basic protein	Homo sapiens	127-147
2480186-5	1989	Our results support an important modulation by sulfatide and galactocerebroside on the interactions among membranes induced by myelin basic protein, depending on the relative proportions of the glycosphingolipids and phosphatidylcholine.	Phosphatidylcholines	217-236	myelin basic protein	Homo sapiens	127-147
2477486-7	1989	It appears that the human MBP gene has evolved by recombination of an ancestral nonfibrillar collagen gene with a gene that encodes carbohydrate recognition, and is therefore similar to the human surfactant SP-A gene and the rat MBP gene.	Carbohydrates	132-144	myelin basic protein	Homo sapiens	26-29
2597155-4	1989	On the other hand using basic protein (H2B histone and myelin basic protein) as substrates, phosphatidic acid stimulated the activity of CPTK-40, while phosphatidylinositol inhibited the activity.	Phosphatidic Acids	92-109	myelin basic protein	Homo sapiens	55-75
2479764-2	1989	Antibodies to galactocerebroside (GalC) cause patching of this surface glycolipid over internal domains of myelin basic protein (MBP), which are demarcated by a network of microtubules.	galactocerebroside	14-32	myelin basic protein	Homo sapiens	107-127
2479764-2	1989	Antibodies to galactocerebroside (GalC) cause patching of this surface glycolipid over internal domains of myelin basic protein (MBP), which are demarcated by a network of microtubules.	galactocerebroside	14-32	myelin basic protein	Homo sapiens	129-132
2474454-3	1989	The matching sites within chol B consisted of a 17 amino acid residue sequence (residues 30-46 in chol B and residues 102-118 in human-MBP, hMBP, p less than 0.0007) and an 11 residue span (residues 31-41 in chol B and sequence 29-39 in hMBP, p less than 0.0004).	chol	26-30	myelin basic protein	Homo sapiens	237-241
2778240-7	1989	Oral prednisone pretreatment significantly reduced the mean of each subject"s peak late-phase concentration of both MBP (30.7 +/- 5.8 ng/ml versus 13.3 +/- 4.3 ng/ml; p = 0.005) and EDN (885 +/- 659 ng/ml versus 71 +/- 41 ng/ml; p less than 0.05).	Prednisone	5-15	myelin basic protein	Homo sapiens	116-119
2590164-7	1989	The MBP molecule comprises a signal peptide, a cysteine-rich domain, a collagen-like domain, a "neck" region and a carbohydrate-binding domain.	Cysteine	47-55	myelin basic protein	Homo sapiens	4-7
2590164-7	1989	The MBP molecule comprises a signal peptide, a cysteine-rich domain, a collagen-like domain, a "neck" region and a carbohydrate-binding domain.	Carbohydrates	115-127	myelin basic protein	Homo sapiens	4-7
2474454-1	1989	Recent reports that myelin basic protein (MBP) can be ADP-ribosylated and contains specific sites that bind GTP and GM1 ganglioside, have suggested an analogy to the properties of cholera toxin.	Guanosine Triphosphate	108-111	myelin basic protein	Homo sapiens	20-40
2474454-1	1989	Recent reports that myelin basic protein (MBP) can be ADP-ribosylated and contains specific sites that bind GTP and GM1 ganglioside, have suggested an analogy to the properties of cholera toxin.	Guanosine Triphosphate	108-111	myelin basic protein	Homo sapiens	42-45
2474454-4	1989	The homologous site within chol A corresponded to an 11 residue span (residues 130-140 in chol A and 67-77 in hMBP sequence, p less than 0.00007).	chol a	27-33	myelin basic protein	Homo sapiens	110-114
2474454-1	1989	Recent reports that myelin basic protein (MBP) can be ADP-ribosylated and contains specific sites that bind GTP and GM1 ganglioside, have suggested an analogy to the properties of cholera toxin.	G(M1) Ganglioside	116-131	myelin basic protein	Homo sapiens	20-40
2474454-1	1989	Recent reports that myelin basic protein (MBP) can be ADP-ribosylated and contains specific sites that bind GTP and GM1 ganglioside, have suggested an analogy to the properties of cholera toxin.	G(M1) Ganglioside	116-131	myelin basic protein	Homo sapiens	42-45
2660359-5	1989	Plasma MBP concentrations were within the normal range in both acute rejection and cyclosporine nephrotoxicity.	Cyclosporine	83-95	myelin basic protein	Homo sapiens	7-10
2474454-3	1989	The matching sites within chol B consisted of a 17 amino acid residue sequence (residues 30-46 in chol B and residues 102-118 in human-MBP, hMBP, p less than 0.0007) and an 11 residue span (residues 31-41 in chol B and sequence 29-39 in hMBP, p less than 0.0004).	chol b	26-32	myelin basic protein	Homo sapiens	135-138
2474454-3	1989	The matching sites within chol B consisted of a 17 amino acid residue sequence (residues 30-46 in chol B and residues 102-118 in human-MBP, hMBP, p less than 0.0007) and an 11 residue span (residues 31-41 in chol B and sequence 29-39 in hMBP, p less than 0.0004).	chol b	26-32	myelin basic protein	Homo sapiens	140-144
2474454-3	1989	The matching sites within chol B consisted of a 17 amino acid residue sequence (residues 30-46 in chol B and residues 102-118 in human-MBP, hMBP, p less than 0.0007) and an 11 residue span (residues 31-41 in chol B and sequence 29-39 in hMBP, p less than 0.0004).	chol b	26-32	myelin basic protein	Homo sapiens	237-241
2474454-3	1989	The matching sites within chol B consisted of a 17 amino acid residue sequence (residues 30-46 in chol B and residues 102-118 in human-MBP, hMBP, p less than 0.0007) and an 11 residue span (residues 31-41 in chol B and sequence 29-39 in hMBP, p less than 0.0004).	chol	26-30	myelin basic protein	Homo sapiens	135-138
2474454-3	1989	The matching sites within chol B consisted of a 17 amino acid residue sequence (residues 30-46 in chol B and residues 102-118 in human-MBP, hMBP, p less than 0.0007) and an 11 residue span (residues 31-41 in chol B and sequence 29-39 in hMBP, p less than 0.0004).	chol	26-30	myelin basic protein	Homo sapiens	140-144
2480216-0	1989	Cyclic AMP regulation of P0 glycoprotein and myelin basic protein gene expression in semi-differentiated peripheral neurinoma cell line D6P2T.	Cyclic AMP	0-10	myelin basic protein	Homo sapiens	45-65
2473753-2	1989	Myelin basic protein treated with the crosslinking reagent dithiobis(succinimidylpropionate) was subjected to analysis by urea-SDS polyacrylamide gel electrophoresis.	dithiobis	59-68	myelin basic protein	Homo sapiens	0-20
2473753-2	1989	Myelin basic protein treated with the crosslinking reagent dithiobis(succinimidylpropionate) was subjected to analysis by urea-SDS polyacrylamide gel electrophoresis.	succinimidylpropionate	69-91	myelin basic protein	Homo sapiens	0-20
2473753-2	1989	Myelin basic protein treated with the crosslinking reagent dithiobis(succinimidylpropionate) was subjected to analysis by urea-SDS polyacrylamide gel electrophoresis.	Urea	122-126	myelin basic protein	Homo sapiens	0-20
2473753-2	1989	Myelin basic protein treated with the crosslinking reagent dithiobis(succinimidylpropionate) was subjected to analysis by urea-SDS polyacrylamide gel electrophoresis.	polyacrylamide	131-145	myelin basic protein	Homo sapiens	0-20
2469767-1	1989	The human mannose-binding protein (MBP) is a multimeric serum protein that is divided into three domains: a cysteine-rich NH2-terminal domain that stabilizes the alpha-helix of the second collagen-like domain, and a third COOH-terminal carbohydrate binding region.	Cysteine	108-116	myelin basic protein	Homo sapiens	10-33
2475178-1	1989	Semi-empirical energy calculations are used to determine all low-energy conformations of Trp-containing fragment 113-121 of myelin basic protein (experimental allergic encephalomyelitis inducing peptide).	Tryptophan	89-92	myelin basic protein	Homo sapiens	124-144
2475162-1	1989	Myelin basic protein (MBP), isolated from normal human myelin, was glycosylated with UDP-N-acetyl-D-galactosamine and a glycosyltransferase isolated from porcine submaxillary glands.	UDP-N-acetyl-D-galactosamine	85-113	myelin basic protein	Homo sapiens	0-20
2475162-1	1989	Myelin basic protein (MBP), isolated from normal human myelin, was glycosylated with UDP-N-acetyl-D-galactosamine and a glycosyltransferase isolated from porcine submaxillary glands.	UDP-N-acetyl-D-galactosamine	85-113	myelin basic protein	Homo sapiens	22-25
2475162-2	1989	MBP containing 0.85 mol of N-acetyl-D-galactosamine per mole of protein was oxidized at carbon 6 by galactose oxidase and complexed with a spin-label, Tempoamine, in order to study its interactions with lipids.	Acetylgalactosamine	27-51	myelin basic protein	Homo sapiens	0-3
2469767-1	1989	The human mannose-binding protein (MBP) is a multimeric serum protein that is divided into three domains: a cysteine-rich NH2-terminal domain that stabilizes the alpha-helix of the second collagen-like domain, and a third COOH-terminal carbohydrate binding region.	Cysteine	108-116	myelin basic protein	Homo sapiens	35-38
2475162-2	1989	MBP containing 0.85 mol of N-acetyl-D-galactosamine per mole of protein was oxidized at carbon 6 by galactose oxidase and complexed with a spin-label, Tempoamine, in order to study its interactions with lipids.	carbon 6	88-96	myelin basic protein	Homo sapiens	0-3
2469767-2	1989	The function of MBP is unknown, although a role in host defense is suggested by its ability to bind yeast mannans.	Mannans	106-113	myelin basic protein	Homo sapiens	16-19
2475162-2	1989	MBP containing 0.85 mol of N-acetyl-D-galactosamine per mole of protein was oxidized at carbon 6 by galactose oxidase and complexed with a spin-label, Tempoamine, in order to study its interactions with lipids.	4-amino-TEMPO	151-161	myelin basic protein	Homo sapiens	0-3
2469767-3	1989	In this report we show that native and recombinant human MBP can serve in an opsonic role in serum and thereby enhance clearance of mannose rich pathogens by phagocytes.	Mannose	132-139	myelin basic protein	Homo sapiens	57-60
2475162-3	1989	When the spin-labeled MBP was reacted with lipid vesicles consisting of DSPG, DPPG, and DMPG, most of the spin-label was motionally restricted in the gel phase, with a correlation time greater than 10(-8)s. The motion increased with increasing temperature and was sensitive to the lipid phase transition.	1,2-dipalmitoylphosphatidylglycerol	78-82	myelin basic protein	Homo sapiens	22-25
2475162-3	1989	When the spin-labeled MBP was reacted with lipid vesicles consisting of DSPG, DPPG, and DMPG, most of the spin-label was motionally restricted in the gel phase, with a correlation time greater than 10(-8)s. The motion increased with increasing temperature and was sensitive to the lipid phase transition.	dimyristoylphosphatidylglycerol	88-92	myelin basic protein	Homo sapiens	22-25
2469767-4	1989	MBP binds to wild-type virulent Salmonella montevideo that express a mannose-rich O-polysaccharide.	Mannose	69-76	myelin basic protein	Homo sapiens	0-3
2475162-9	1989	When nonglycosylated and glycosylated MBP in solution was treated with Lys-C, extensive digestion occurred.	lys-c	71-76	myelin basic protein	Homo sapiens	38-41
2469767-4	1989	MBP binds to wild-type virulent Salmonella montevideo that express a mannose-rich O-polysaccharide.	o-polysaccharide	82-98	myelin basic protein	Homo sapiens	0-3
2658681-8	1989	Definitive identification of labeled phosphoserine residues in histone, phosphoserine and phosphothreonine residues in myelin basic protein and insulin receptor, and phosphotyrosine residues in autophosphorylated insulin receptor was accomplished with as little as 0.2 nCi in about 50 ng of phosphorylated protein.	Phosphoserine	37-50	myelin basic protein	Homo sapiens	119-139
2469646-1	1989	Eosinophil granule major basic protein (MBP) is a 13,800 MW arginine-rich polypeptide that is unique among basic molecules in its ability to stimulate human basophil histamine release.	Histamine	166-175	myelin basic protein	Homo sapiens	40-43
2469646-2	1989	We examined the Ca2+ requirements and pharmacological regulation of MBP-stimulated histamine release.	Histamine	83-92	myelin basic protein	Homo sapiens	68-71
2469646-3	1989	Minimal MBP-induced histamine release occurred in the absence of extracellular Ca2+, whereas addition of 0.1 mM Ca2+ resulted in 70% of the maximum histamine release response.	Histamine	20-29	myelin basic protein	Homo sapiens	8-11
2469646-5	1989	The MBP-induced histamine release was blocked by a calmodulin antagonist and by theophylline and was partially inhibited by an inhibitor of phospholipase A2.	Histamine	16-25	myelin basic protein	Homo sapiens	4-7
2469646-5	1989	The MBP-induced histamine release was blocked by a calmodulin antagonist and by theophylline and was partially inhibited by an inhibitor of phospholipase A2.	Theophylline	80-92	myelin basic protein	Homo sapiens	4-7
2469646-7	1989	Histamine release stimulated by a 13,900 MW poly-L-arginine exhibited a dissimilar pharmacological profile from that of MBP.	Histamine	0-9	myelin basic protein	Homo sapiens	120-123
2469646-7	1989	Histamine release stimulated by a 13,900 MW poly-L-arginine exhibited a dissimilar pharmacological profile from that of MBP.	polyarginine	44-59	myelin basic protein	Homo sapiens	120-123
2658681-8	1989	Definitive identification of labeled phosphoserine residues in histone, phosphoserine and phosphothreonine residues in myelin basic protein and insulin receptor, and phosphotyrosine residues in autophosphorylated insulin receptor was accomplished with as little as 0.2 nCi in about 50 ng of phosphorylated protein.	Phosphothreonine	90-106	myelin basic protein	Homo sapiens	119-139
2484437-1	1989	Compound 1,2-isopropylidene-3-decanoyl-sn-glycerol (IpOCOC9) augments the phosphorylation in vitro of histone III-S and myelin basic protein (MBP) by a partially purified Ca2(+)- and phospholipid-dependent protein kinase activity (protein kinase C) from human polymorphonuclear leukocytes.	1,2-isopropylidene-3-decanoylglycerol	52-59	myelin basic protein	Homo sapiens	142-145
2465762-2	1989	However, this polyamine inhibited the enzyme activities when myelin basic protein, tubulin and H2B histone were used as substrate proteins.	Polyamines	14-23	myelin basic protein	Homo sapiens	61-81
2485126-8	1989	The moderate dose prednisone therapy and Mega-dose Solu-Medrol therapy on CSF IgG anti-MBP antibody specific activity were less effective than the Mega-dose prednisone medication.	Prednisone	18-28	myelin basic protein	Homo sapiens	87-90
2485126-8	1989	The moderate dose prednisone therapy and Mega-dose Solu-Medrol therapy on CSF IgG anti-MBP antibody specific activity were less effective than the Mega-dose prednisone medication.	Methylprednisolone Hemisuccinate	51-62	myelin basic protein	Homo sapiens	87-90
2484437-1	1989	Compound 1,2-isopropylidene-3-decanoyl-sn-glycerol (IpOCOC9) augments the phosphorylation in vitro of histone III-S and myelin basic protein (MBP) by a partially purified Ca2(+)- and phospholipid-dependent protein kinase activity (protein kinase C) from human polymorphonuclear leukocytes.	1,2-isopropylidene-3-decanoyl-sn-glycerol	9-50	myelin basic protein	Homo sapiens	120-140
2484437-1	1989	Compound 1,2-isopropylidene-3-decanoyl-sn-glycerol (IpOCOC9) augments the phosphorylation in vitro of histone III-S and myelin basic protein (MBP) by a partially purified Ca2(+)- and phospholipid-dependent protein kinase activity (protein kinase C) from human polymorphonuclear leukocytes.	1,2-isopropylidene-3-decanoyl-sn-glycerol	9-50	myelin basic protein	Homo sapiens	142-145
2484437-1	1989	Compound 1,2-isopropylidene-3-decanoyl-sn-glycerol (IpOCOC9) augments the phosphorylation in vitro of histone III-S and myelin basic protein (MBP) by a partially purified Ca2(+)- and phospholipid-dependent protein kinase activity (protein kinase C) from human polymorphonuclear leukocytes.	1,2-isopropylidene-3-decanoylglycerol	52-59	myelin basic protein	Homo sapiens	120-140
2465309-5	1989	In contrast, cyclosporin A and WW.T4 blocked the four antigen-specific functions of the autoimmune myelin basic protein-specific human T cell clones measured.	Cyclosporine	13-26	myelin basic protein	Homo sapiens	99-119
2484441-4	1989	S-Adenosyl-L-homocysteine, a potent product inhibitor for the methyltransferase, inhibited approximately 90% of MBP-specific protein methylase I activity at a concentration of 1 mM.	S-Adenosylhomocysteine	0-25	myelin basic protein	Homo sapiens	112-115
2478466-0	1989	Phosphorylation of myelin basic protein in intact oligodendrocytes: inhibition by galactosylsphingosine and cyclic AMP.	Psychosine	82-103	myelin basic protein	Homo sapiens	19-39
2484441-6	1989	Identity of exogenously added MBP as the methylated substrate for CSF enzyme was confirmed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.	Sodium Dodecyl Sulfate	94-116	myelin basic protein	Homo sapiens	30-33
2478466-3	1989	In this report we define further the mechanism by which cAMP inhibits MBP phosphorylation by comparing the effects of cAMP with that of galactosylsphingosine (psychosine), a potential catabolite of galactocerebroside, the major OLG glycosphingolipid.	Psychosine	136-157	myelin basic protein	Homo sapiens	70-73
2484441-6	1989	Identity of exogenously added MBP as the methylated substrate for CSF enzyme was confirmed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.	polyacrylamide	117-131	myelin basic protein	Homo sapiens	30-33
2478466-3	1989	In this report we define further the mechanism by which cAMP inhibits MBP phosphorylation by comparing the effects of cAMP with that of galactosylsphingosine (psychosine), a potential catabolite of galactocerebroside, the major OLG glycosphingolipid.	Psychosine	159-169	myelin basic protein	Homo sapiens	70-73
2478466-3	1989	In this report we define further the mechanism by which cAMP inhibits MBP phosphorylation by comparing the effects of cAMP with that of galactosylsphingosine (psychosine), a potential catabolite of galactocerebroside, the major OLG glycosphingolipid.	galactocerebroside	198-216	myelin basic protein	Homo sapiens	70-73
2462252-0	1988	Specific inhibition of the T-cell response to myelin basic protein by the synthetic copolymer Cop 1.	copolymer	84-93	myelin basic protein	Homo sapiens	46-66
2478466-3	1989	In this report we define further the mechanism by which cAMP inhibits MBP phosphorylation by comparing the effects of cAMP with that of galactosylsphingosine (psychosine), a potential catabolite of galactocerebroside, the major OLG glycosphingolipid.	Glycosphingolipids	232-249	myelin basic protein	Homo sapiens	70-73
2478466-5	1989	Our results in intact ovine oligodendrocytes are consistent with a mechanism in which cAMP inhibits MBP phosphorylation by interfering with the release of diacylglycerol (DAG) from phosphatidylinositol.	Diglycerides	155-169	myelin basic protein	Homo sapiens	100-103
2478466-5	1989	Our results in intact ovine oligodendrocytes are consistent with a mechanism in which cAMP inhibits MBP phosphorylation by interfering with the release of diacylglycerol (DAG) from phosphatidylinositol.	Phosphatidylinositols	181-201	myelin basic protein	Homo sapiens	100-103
2478466-6	1989	First, the effects of cAMP on MBP phosphorylation are reversed with exogenous TPA; and second, cAMP inhibits the incorporation of 1-[14C]arachidonate into DAG and specifically inhibits the turnover (as judged by 32PO4 3-incorporation) of phosphatidylinositol.	Tetradecanoylphorbol Acetate	78-81	myelin basic protein	Homo sapiens	30-33
2478466-6	1989	First, the effects of cAMP on MBP phosphorylation are reversed with exogenous TPA; and second, cAMP inhibits the incorporation of 1-[14C]arachidonate into DAG and specifically inhibits the turnover (as judged by 32PO4 3-incorporation) of phosphatidylinositol.	Diglycerides	155-158	myelin basic protein	Homo sapiens	30-33
2478466-6	1989	First, the effects of cAMP on MBP phosphorylation are reversed with exogenous TPA; and second, cAMP inhibits the incorporation of 1-[14C]arachidonate into DAG and specifically inhibits the turnover (as judged by 32PO4 3-incorporation) of phosphatidylinositol.	32po4	212-217	myelin basic protein	Homo sapiens	30-33
2478466-6	1989	First, the effects of cAMP on MBP phosphorylation are reversed with exogenous TPA; and second, cAMP inhibits the incorporation of 1-[14C]arachidonate into DAG and specifically inhibits the turnover (as judged by 32PO4 3-incorporation) of phosphatidylinositol.	Phosphatidylinositols	238-258	myelin basic protein	Homo sapiens	30-33
2478466-7	1989	Psychosine inhibits MBP phosphorylation, and its action can be reversed by TPA suggesting a mechanism of inhibition similar to that described for other systems.	Psychosine	0-10	myelin basic protein	Homo sapiens	20-23
2467365-4	1989	In the present study, we investigated by a combined 3H-Thymidine autoradiography/immunocytochemistry technique whether the mitogenic effect that MBP exerts upon astrocytes in vitro can be prevented by DHEA and DHEA-S.	3h-thymidine	52-64	myelin basic protein	Homo sapiens	145-148
2467365-4	1989	In the present study, we investigated by a combined 3H-Thymidine autoradiography/immunocytochemistry technique whether the mitogenic effect that MBP exerts upon astrocytes in vitro can be prevented by DHEA and DHEA-S.	Dehydroepiandrosterone	201-205	myelin basic protein	Homo sapiens	145-148
2467365-4	1989	In the present study, we investigated by a combined 3H-Thymidine autoradiography/immunocytochemistry technique whether the mitogenic effect that MBP exerts upon astrocytes in vitro can be prevented by DHEA and DHEA-S.	Dehydroepiandrosterone	210-216	myelin basic protein	Homo sapiens	145-148
3199069-7	1988	The NH2-terminal half has a predicted pI of 3.7 and is hydrophilic, while the COOH-terminal half (corresponding to mature MBP) has a predicted pI of 11.1 and is hydrophobic.	Carbonic Acid	78-82	myelin basic protein	Homo sapiens	122-125
2465828-0	1988	Fluorescence spectral resolution of myelin basic protein conformers in complexes with lysophosphatidylcholine.	Lysophosphatidylcholines	86-109	myelin basic protein	Homo sapiens	36-56
2465828-1	1988	The structure of (Deibler) myelin basic protein in solution and in a lysolecithin++ lipid complex has been studied by using the emission properties of the single tryptophan residue of the protein (Trp-115).	lysolecithin++ lipid	69-89	myelin basic protein	Homo sapiens	27-47
2465828-1	1988	The structure of (Deibler) myelin basic protein in solution and in a lysolecithin++ lipid complex has been studied by using the emission properties of the single tryptophan residue of the protein (Trp-115).	Tryptophan	162-172	myelin basic protein	Homo sapiens	27-47
2465828-1	1988	The structure of (Deibler) myelin basic protein in solution and in a lysolecithin++ lipid complex has been studied by using the emission properties of the single tryptophan residue of the protein (Trp-115).	Tryptophan	197-200	myelin basic protein	Homo sapiens	27-47
3183059-6	1988	Unlike the macrophage LDL receptor, MBP 190 partitions into the aqueous phase after phase separation of Triton X-114 extracts.	Nonidet P-40	104-116	myelin basic protein	Homo sapiens	36-39
2464075-9	1988	The phorbol ester 12-O-tetradecanoyl phorbol acetate was found to reduce intracellular MBP RNA levels.	Phorbol Esters	4-17	myelin basic protein	Homo sapiens	87-90
2459156-5	1988	It is possible with synthetic peptides to generate antibodies of specificities which it would be impossible to achieve by immunisation with intact myelin basic protein.	Peptides	30-38	myelin basic protein	Homo sapiens	147-167
2464075-9	1988	The phorbol ester 12-O-tetradecanoyl phorbol acetate was found to reduce intracellular MBP RNA levels.	Tetradecanoylphorbol Acetate	18-52	myelin basic protein	Homo sapiens	87-90
2464075-10	1988	The cAMP analogue/dibutyryl cAMP had contrasting effects on MBP RNA levels; no effect occurred in cultures grown in fetal calf serum, but a reduction in RNA levels was found in cultures grown in ODM.	Cyclic AMP	4-8	myelin basic protein	Homo sapiens	60-63
2464075-10	1988	The cAMP analogue/dibutyryl cAMP had contrasting effects on MBP RNA levels; no effect occurred in cultures grown in fetal calf serum, but a reduction in RNA levels was found in cultures grown in ODM.	Cyclic AMP	28-32	myelin basic protein	Homo sapiens	60-63
2465387-7	1988	If CSF MBP is an indicator of the (activity of) myelin breakdown in the brain, it can be concluded that an intensive immunosuppressive treatment in combination with prednisone has, at least, a short-term, beneficial effect on the amount of demyelinisation and possibly on the disease activity.	Prednisone	165-175	myelin basic protein	Homo sapiens	7-10
3410852-4	1988	Less conventional chemical reactions, including cyanogen bromide-induced cleavage at tryptophan and acid-induced cleavage at aspartic acid, were used successfully to obtain peptides which allowed definition of the amino acid sequence of MBP.	Cyanogen Bromide	48-64	myelin basic protein	Homo sapiens	237-240
2458139-0	1988	The glycosylation of human myelin basic protein at threonines 95 and 98 occurs sequentially.	Threonine	51-61	myelin basic protein	Homo sapiens	27-47
2458139-1	1988	Human myelin basic protein (MBP) was glycosylated by the enzyme, UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase (EC 2.4.2.41).	Uridine Diphosphate N-Acetylgalactosamine	65-75	myelin basic protein	Homo sapiens	6-26
2458139-1	1988	Human myelin basic protein (MBP) was glycosylated by the enzyme, UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase (EC 2.4.2.41).	Uridine Diphosphate N-Acetylgalactosamine	65-75	myelin basic protein	Homo sapiens	28-31
2458139-3	1988	Proton NMR studies of basic protein glycosylated with 0.48-1.7 mol of GalNAc/mol of MBP showed that the order of addition to the two threonine residues is not random but sequential.	N-acetylgalactosaminuronic acid	70-76	myelin basic protein	Homo sapiens	84-87
2458139-3	1988	Proton NMR studies of basic protein glycosylated with 0.48-1.7 mol of GalNAc/mol of MBP showed that the order of addition to the two threonine residues is not random but sequential.	Threonine	133-142	myelin basic protein	Homo sapiens	84-87
3171483-1	1988	Eosinophil granule major basic protein (MBP), a potent toxin for helminths and various cell types, is a 13.8-kD single polypeptide rich in arginine with a calculated isoelectric point (pI) of 10.9.	Arginine	139-147	myelin basic protein	Homo sapiens	40-43
3410852-4	1988	Less conventional chemical reactions, including cyanogen bromide-induced cleavage at tryptophan and acid-induced cleavage at aspartic acid, were used successfully to obtain peptides which allowed definition of the amino acid sequence of MBP.	Tryptophan	85-95	myelin basic protein	Homo sapiens	237-240
3410852-4	1988	Less conventional chemical reactions, including cyanogen bromide-induced cleavage at tryptophan and acid-induced cleavage at aspartic acid, were used successfully to obtain peptides which allowed definition of the amino acid sequence of MBP.	Aspartic Acid	125-138	myelin basic protein	Homo sapiens	237-240
2456309-3	1988	After treatment with pyroglutamyl aminopeptidase, N-terminal sequencing indicated that Gln74 of MBP formed the N-terminal residue of peptide C. A rabbit antiserum was raised to a synthetic peptide containing the sequence Pyroglu-Lys-Ser-His-Gly-Arg, corresponding to the first six residues of peptide C. By immunoblotting this serum reacted with peptide C but not with intact MBP.	Lysine	229-232	myelin basic protein	Homo sapiens	96-99
2457650-8	1988	A second effect was evident only in the presence of added calcium ions, when lower concentrations of Zn2+ (less than 0.1 mM) inhibited MBP-membrane dissociation and the accumulation of intact MBP in incubation media.	Calcium	58-65	myelin basic protein	Homo sapiens	135-138
2457650-8	1988	A second effect was evident only in the presence of added calcium ions, when lower concentrations of Zn2+ (less than 0.1 mM) inhibited MBP-membrane dissociation and the accumulation of intact MBP in incubation media.	Calcium	58-65	myelin basic protein	Homo sapiens	192-195
2457650-8	1988	A second effect was evident only in the presence of added calcium ions, when lower concentrations of Zn2+ (less than 0.1 mM) inhibited MBP-membrane dissociation and the accumulation of intact MBP in incubation media.	Zinc	101-105	myelin basic protein	Homo sapiens	135-138
2457650-8	1988	A second effect was evident only in the presence of added calcium ions, when lower concentrations of Zn2+ (less than 0.1 mM) inhibited MBP-membrane dissociation and the accumulation of intact MBP in incubation media.	Zinc	101-105	myelin basic protein	Homo sapiens	192-195
3202421-6	1988	MBP did not affect the reactivity of rings in which the epithelium had been removed, but significantly augmented that of unrubbed rings to acetylcholine and histamine.	Acetylcholine	139-152	myelin basic protein	Homo sapiens	0-3
3202421-6	1988	MBP did not affect the reactivity of rings in which the epithelium had been removed, but significantly augmented that of unrubbed rings to acetylcholine and histamine.	Histamine	157-166	myelin basic protein	Homo sapiens	0-3
3414778-3	1988	A single-step propidium iodide exclusion assay was then used to show that EPO + MBP in the absence of hydrogen peroxide is substantially cytotoxic only to the acute lymphocytic leukemia and IM-9 cells.	Propidium	14-30	myelin basic protein	Homo sapiens	80-83
3414778-4	1988	In the presence of 0.003% hydrogen peroxide, EPO + MBP was cytotoxic to five types of cells.	Hydrogen Peroxide	26-43	myelin basic protein	Homo sapiens	51-54
3414778-6	1988	The toxicity of EPO + MBP is markedly enhanced by the presence of hydrogen peroxide.	Hydrogen Peroxide	66-83	myelin basic protein	Homo sapiens	22-25
2456309-3	1988	After treatment with pyroglutamyl aminopeptidase, N-terminal sequencing indicated that Gln74 of MBP formed the N-terminal residue of peptide C. A rabbit antiserum was raised to a synthetic peptide containing the sequence Pyroglu-Lys-Ser-His-Gly-Arg, corresponding to the first six residues of peptide C. By immunoblotting this serum reacted with peptide C but not with intact MBP.	Serine	233-236	myelin basic protein	Homo sapiens	96-99
2456309-3	1988	After treatment with pyroglutamyl aminopeptidase, N-terminal sequencing indicated that Gln74 of MBP formed the N-terminal residue of peptide C. A rabbit antiserum was raised to a synthetic peptide containing the sequence Pyroglu-Lys-Ser-His-Gly-Arg, corresponding to the first six residues of peptide C. By immunoblotting this serum reacted with peptide C but not with intact MBP.	Histidine	237-240	myelin basic protein	Homo sapiens	96-99
2456309-3	1988	After treatment with pyroglutamyl aminopeptidase, N-terminal sequencing indicated that Gln74 of MBP formed the N-terminal residue of peptide C. A rabbit antiserum was raised to a synthetic peptide containing the sequence Pyroglu-Lys-Ser-His-Gly-Arg, corresponding to the first six residues of peptide C. By immunoblotting this serum reacted with peptide C but not with intact MBP.	Glycine	241-244	myelin basic protein	Homo sapiens	96-99
2456309-3	1988	After treatment with pyroglutamyl aminopeptidase, N-terminal sequencing indicated that Gln74 of MBP formed the N-terminal residue of peptide C. A rabbit antiserum was raised to a synthetic peptide containing the sequence Pyroglu-Lys-Ser-His-Gly-Arg, corresponding to the first six residues of peptide C. By immunoblotting this serum reacted with peptide C but not with intact MBP.	Arginine	245-248	myelin basic protein	Homo sapiens	96-99
2846259-4	1988	In this report, we demonstrate that expression of the P0 and MBP genes in rapidly myelinating Schwann cells is sharply reduced upon withdrawal of axons, but that this expression can be substantially restored by agents that raise the intracellular concentration of cyclic AMP.	Cyclic AMP	264-274	myelin basic protein	Homo sapiens	61-64
2454105-0	1988	Myelin basic protein binds GTP at a single site in the N-terminus.	Guanosine Triphosphate	27-30	myelin basic protein	Homo sapiens	0-20
2452382-1	1988	Forty myelin basic protein (BP)-reactive T-cell clones were isolated from a patient with multiple sclerosis and used to identify human T-cell recognition sites on the BP molecule.	Benzo(a)pyrene	28-30	myelin basic protein	Homo sapiens	6-26
3290717-3	1988	In saline, MBP suppresses EAE.	Sodium Chloride	3-9	myelin basic protein	Homo sapiens	11-14
3346544-2	1988	Purified MBP was studied for capacity to regulate the generation of classical and alternative-amplification pathway C3 convertases because previous studies have shown that other polycations (protamine, poly-L-lysine) and polyanions (heparin) may play important roles in regulating C activation.	Lysine	202-215	myelin basic protein	Homo sapiens	9-12
3346544-2	1988	Purified MBP was studied for capacity to regulate the generation of classical and alternative-amplification pathway C3 convertases because previous studies have shown that other polycations (protamine, poly-L-lysine) and polyanions (heparin) may play important roles in regulating C activation.	Heparin	233-240	myelin basic protein	Homo sapiens	9-12
2449503-3	1988	Excellent resolution of a mixture of myelin basic protein (MBP) peptides was achieved by electrophoresis in a polyacrylamide stacking, urea-dodecyl sulphate minislab gel.	polyacrylamide	110-124	myelin basic protein	Homo sapiens	37-57
2449503-3	1988	Excellent resolution of a mixture of myelin basic protein (MBP) peptides was achieved by electrophoresis in a polyacrylamide stacking, urea-dodecyl sulphate minislab gel.	polyacrylamide	110-124	myelin basic protein	Homo sapiens	59-62
2449503-3	1988	Excellent resolution of a mixture of myelin basic protein (MBP) peptides was achieved by electrophoresis in a polyacrylamide stacking, urea-dodecyl sulphate minislab gel.	urea-dodecyl sulphate	135-156	myelin basic protein	Homo sapiens	37-57
2449503-3	1988	Excellent resolution of a mixture of myelin basic protein (MBP) peptides was achieved by electrophoresis in a polyacrylamide stacking, urea-dodecyl sulphate minislab gel.	urea-dodecyl sulphate	135-156	myelin basic protein	Homo sapiens	59-62
2450567-3	1988	The spin-labels 5-, 12-, and 16-doxylstearate have been incorporated into DPC/MBP aggregates.	doxylstearate	32-45	myelin basic protein	Homo sapiens	78-81
2449243-0	1988	25-Hydroxycholesterol promotes myelin basic protein-induced leakage of phospholipid vesicles.	25-hydroxycholesterol	0-21	myelin basic protein	Homo sapiens	31-51
2448785-11	1988	These findings, in conjunction with our earlier work, implicate cAMP and diacylglycerol in signaling myelinogenesis; they suggest that phosphorylation/dephosphorylation of myelin basic protein and 2",3"-cyclic nucleotide 2"-phosphodiesterase may be key processes in the cascade of events that are initiated by adhesion of OLG to a polylysine surface (possibly acting as a surrogate for axons) and culminate in the reformation of myelin.	Diglycerides	73-87	myelin basic protein	Homo sapiens	172-192
2448785-11	1988	These findings, in conjunction with our earlier work, implicate cAMP and diacylglycerol in signaling myelinogenesis; they suggest that phosphorylation/dephosphorylation of myelin basic protein and 2",3"-cyclic nucleotide 2"-phosphodiesterase may be key processes in the cascade of events that are initiated by adhesion of OLG to a polylysine surface (possibly acting as a surrogate for axons) and culminate in the reformation of myelin.	Polylysine	331-341	myelin basic protein	Homo sapiens	172-192
2446664-0	1988	Photolabeling of myelin basic protein in lipid vesicles with the hydrophobic reagent 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine.	3-(trifluoromethyl)-3-(m-[125i]iodophenyl)diazirine	85-136	myelin basic protein	Homo sapiens	17-37
2446664-1	1988	The hydrophobic photolabel 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine([125I]TID) was used to label myelin basic protein or polylysine in aqueous solution and bound to lipid vesicles of different composition.	3-(trifluoromethyl)-3-(m-[125i]iodophenyl)diazirine	27-78	myelin basic protein	Homo sapiens	108-128
2446664-2	1988	Although myelin basic protein is a water soluble protein which binds electrostatically only to acidic lipids, unlike polylysine it has several short hydrophobic regions.	Water	35-40	myelin basic protein	Homo sapiens	9-29
2446664-4	1988	However, myelin basic protein was labeled 2-4-times more when bound to the acidic lipids phosphatidylglycerol, phosphatidylserine, phosphatidic acid, and cerebroside sulfate than when bound to phosphatidylethanolamine, or when in solution in the presence of phosphatidylcholine vesicles.	Phosphatidylglycerols	89-109	myelin basic protein	Homo sapiens	9-29
2446664-4	1988	However, myelin basic protein was labeled 2-4-times more when bound to the acidic lipids phosphatidylglycerol, phosphatidylserine, phosphatidic acid, and cerebroside sulfate than when bound to phosphatidylethanolamine, or when in solution in the presence of phosphatidylcholine vesicles.	Phosphatidylserines	111-129	myelin basic protein	Homo sapiens	9-29
2446664-4	1988	However, myelin basic protein was labeled 2-4-times more when bound to the acidic lipids phosphatidylglycerol, phosphatidylserine, phosphatidic acid, and cerebroside sulfate than when bound to phosphatidylethanolamine, or when in solution in the presence of phosphatidylcholine vesicles.	Phosphatidic Acids	131-148	myelin basic protein	Homo sapiens	9-29
2446664-4	1988	However, myelin basic protein was labeled 2-4-times more when bound to the acidic lipids phosphatidylglycerol, phosphatidylserine, phosphatidic acid, and cerebroside sulfate than when bound to phosphatidylethanolamine, or when in solution in the presence of phosphatidylcholine vesicles.	cerebroside sulfate	154-173	myelin basic protein	Homo sapiens	9-29
2446664-4	1988	However, myelin basic protein was labeled 2-4-times more when bound to the acidic lipids phosphatidylglycerol, phosphatidylserine, phosphatidic acid, and cerebroside sulfate than when bound to phosphatidylethanolamine, or when in solution in the presence of phosphatidylcholine vesicles.	phosphatidylethanolamine	193-217	myelin basic protein	Homo sapiens	9-29
2446664-4	1988	However, myelin basic protein was labeled 2-4-times more when bound to the acidic lipids phosphatidylglycerol, phosphatidylserine, phosphatidic acid, and cerebroside sulfate than when bound to phosphatidylethanolamine, or when in solution in the presence of phosphatidylcholine vesicles.	Phosphatidylcholines	258-277	myelin basic protein	Homo sapiens	9-29
2458016-0	1988	Enzymatic methylation of arginine residue in myelin basic protein.	Arginine	25-33	myelin basic protein	Homo sapiens	45-65
2447826-6	1987	In a group of 39 persons with multiple sclerosis, 48 with other neurological diseases, and 26 normal control subjects, the concentration of urinary MBP-like material, related to the concentration of urinary creatinine, was significantly higher in the multiple sclerosis group (22.0 ng MBP-like material/mg creatinine) than in the other neurological diseases or control groups, in which the values were 7.0 and 3.9 ng MBP-like material/mg creatinine, respectively.	Creatinine	207-217	myelin basic protein	Homo sapiens	148-151
2832354-1	1988	Neuronal spherical bodies, rich in arginine, of catecholamine neurons in man display staining reactions of mitotic chromosomes and myelin basic protein.	Arginine	35-43	myelin basic protein	Homo sapiens	131-151
2832354-1	1988	Neuronal spherical bodies, rich in arginine, of catecholamine neurons in man display staining reactions of mitotic chromosomes and myelin basic protein.	Catecholamines	48-61	myelin basic protein	Homo sapiens	131-151
2447246-0	1988	Racemization of individual aspartate residues in human myelin basic protein.	Aspartic Acid	27-36	myelin basic protein	Homo sapiens	55-75
2447246-1	1988	Human myelin basic protein (MBP), a long-lived brain protein, undergoes gradual racemization of its amino acids, primarily aspartic acid and serine.	Aspartic Acid	123-136	myelin basic protein	Homo sapiens	6-26
2447246-1	1988	Human myelin basic protein (MBP), a long-lived brain protein, undergoes gradual racemization of its amino acids, primarily aspartic acid and serine.	Aspartic Acid	123-136	myelin basic protein	Homo sapiens	28-31
2447246-1	1988	Human myelin basic protein (MBP), a long-lived brain protein, undergoes gradual racemization of its amino acids, primarily aspartic acid and serine.	Serine	141-147	myelin basic protein	Homo sapiens	6-26
2447246-1	1988	Human myelin basic protein (MBP), a long-lived brain protein, undergoes gradual racemization of its amino acids, primarily aspartic acid and serine.	Serine	141-147	myelin basic protein	Homo sapiens	28-31
2447246-5	1988	When the racemization was examined in terms of the beta-structure model of MBP, a correlation was observed in which six aspartate/asparagine residues assumed to be associated with myelin membrane lipids showed little racemization (2.2-4.9% D isomer), whereas five other aspartate residues were more highly racemized (9.9-17.1% D isomer).	Aspartic Acid	120-129	myelin basic protein	Homo sapiens	75-78
2447246-5	1988	When the racemization was examined in terms of the beta-structure model of MBP, a correlation was observed in which six aspartate/asparagine residues assumed to be associated with myelin membrane lipids showed little racemization (2.2-4.9% D isomer), whereas five other aspartate residues were more highly racemized (9.9-17.1% D isomer).	Asparagine	130-140	myelin basic protein	Homo sapiens	75-78
2447246-5	1988	When the racemization was examined in terms of the beta-structure model of MBP, a correlation was observed in which six aspartate/asparagine residues assumed to be associated with myelin membrane lipids showed little racemization (2.2-4.9% D isomer), whereas five other aspartate residues were more highly racemized (9.9-17.1% D isomer).	Aspartic Acid	270-279	myelin basic protein	Homo sapiens	75-78
2465269-3	1988	The major myelin proteins--proteolipid protein (PLP), DM-20, and myelin basic protein (MBP), which dominate the sodium dodecyl sulfate polyacrylamide gel electrophoresis pattern of myelin--were minor components of the plasmalemma.	Sodium Dodecyl Sulfate	112-134	myelin basic protein	Homo sapiens	65-85
2465269-3	1988	The major myelin proteins--proteolipid protein (PLP), DM-20, and myelin basic protein (MBP), which dominate the sodium dodecyl sulfate polyacrylamide gel electrophoresis pattern of myelin--were minor components of the plasmalemma.	Sodium Dodecyl Sulfate	112-134	myelin basic protein	Homo sapiens	87-90
2465269-3	1988	The major myelin proteins--proteolipid protein (PLP), DM-20, and myelin basic protein (MBP), which dominate the sodium dodecyl sulfate polyacrylamide gel electrophoresis pattern of myelin--were minor components of the plasmalemma.	polyacrylamide	135-149	myelin basic protein	Homo sapiens	65-85
2465269-3	1988	The major myelin proteins--proteolipid protein (PLP), DM-20, and myelin basic protein (MBP), which dominate the sodium dodecyl sulfate polyacrylamide gel electrophoresis pattern of myelin--were minor components of the plasmalemma.	polyacrylamide	135-149	myelin basic protein	Homo sapiens	87-90
2447826-6	1987	In a group of 39 persons with multiple sclerosis, 48 with other neurological diseases, and 26 normal control subjects, the concentration of urinary MBP-like material, related to the concentration of urinary creatinine, was significantly higher in the multiple sclerosis group (22.0 ng MBP-like material/mg creatinine) than in the other neurological diseases or control groups, in which the values were 7.0 and 3.9 ng MBP-like material/mg creatinine, respectively.	Creatinine	306-316	myelin basic protein	Homo sapiens	148-151
2447826-6	1987	In a group of 39 persons with multiple sclerosis, 48 with other neurological diseases, and 26 normal control subjects, the concentration of urinary MBP-like material, related to the concentration of urinary creatinine, was significantly higher in the multiple sclerosis group (22.0 ng MBP-like material/mg creatinine) than in the other neurological diseases or control groups, in which the values were 7.0 and 3.9 ng MBP-like material/mg creatinine, respectively.	Creatinine	306-316	myelin basic protein	Homo sapiens	148-151
2441703-0	1987	Differential racemization of aspartate and serine in human myelin basic protein.	Aspartic Acid	29-38	myelin basic protein	Homo sapiens	59-79
2442667-1	1987	Migration properties and occurrence of antibodies against myelin basic protein (MBP) in paired CSF and serum specimens from patients with multiple sclerosis (MS) were demonstrated after agarose isoelectric focusing, immunoblot transfer, and immunoperoxidase staining.	Sepharose	186-193	myelin basic protein	Homo sapiens	80-83
2441703-1	1987	L-Aspartate and L-serine were found to undergo amino acid racemization in brain myelin basic protein (MBP) of aging humans.	Aspartic Acid	0-11	myelin basic protein	Homo sapiens	80-100
2441703-1	1987	L-Aspartate and L-serine were found to undergo amino acid racemization in brain myelin basic protein (MBP) of aging humans.	Aspartic Acid	0-11	myelin basic protein	Homo sapiens	102-105
2441703-0	1987	Differential racemization of aspartate and serine in human myelin basic protein.	Serine	43-49	myelin basic protein	Homo sapiens	59-79
2441703-1	1987	L-Aspartate and L-serine were found to undergo amino acid racemization in brain myelin basic protein (MBP) of aging humans.	Serine	16-24	myelin basic protein	Homo sapiens	80-100
2443163-0	1987	Fourier transform infrared spectroscopic investigation of the interaction between myelin basic protein and dimyristoylphosphatidylglycerol bilayers.	dimyristoylphosphatidylglycerol	107-138	myelin basic protein	Homo sapiens	82-102
2441703-1	1987	L-Aspartate and L-serine were found to undergo amino acid racemization in brain myelin basic protein (MBP) of aging humans.	Serine	16-24	myelin basic protein	Homo sapiens	102-105
2441703-5	1987	Total MBP isolated from SDS-polyacrylamide disc gel electrophoresis of total human myelin proteins (delipidated myelin) was racemized to the same extent as purified MBP, indicating that the racemization observed was not an artifact of the isolation procedure.	Sodium Dodecyl Sulfate	24-27	myelin basic protein	Homo sapiens	6-9
2441703-5	1987	Total MBP isolated from SDS-polyacrylamide disc gel electrophoresis of total human myelin proteins (delipidated myelin) was racemized to the same extent as purified MBP, indicating that the racemization observed was not an artifact of the isolation procedure.	polyacrylamide	28-42	myelin basic protein	Homo sapiens	6-9
3681350-2	1987	Treatment with ammonium chloride, a lysosomal inhibitor, delayed the appearance of the proliferative response to the myelin membranes by 12 h. Processing of myelin within the Schwann cells was followed by the appearance of immunocytochemically detectable myelin basic protein which was first visible at 4 h. Similar to the proliferative response, the appearance of immunoreactive material was delayed by the addition of ammonium chloride.	Ammonium Chloride	15-32	myelin basic protein	Homo sapiens	255-275
2443163-3	1987	The association of myelin basic protein with DMPG results in a broadening of the lipid phase transition, accompanied by an increase in the conformational order of the acyl chains at temperatures below the phase transition.	dimyristoylphosphatidylglycerol	45-49	myelin basic protein	Homo sapiens	19-39
2439084-0	1987	Covalent linkage of phosphoinositides to myelin basic protein: in vitro incorporation of [32P] phosphoinositides to myelin basic protein.	Phosphatidylinositols	20-37	myelin basic protein	Homo sapiens	41-61
2439084-0	1987	Covalent linkage of phosphoinositides to myelin basic protein: in vitro incorporation of [32P] phosphoinositides to myelin basic protein.	Phosphatidylinositols	20-37	myelin basic protein	Homo sapiens	116-136
2443163-5	1987	Infrared spectra of myelin basic protein in the amide I region were analyzed quantitatively by using resolution enhancement and band fitting procedures.	Amides	48-53	myelin basic protein	Homo sapiens	20-40
2442683-7	1987	All four metal salts, in addition to activating endogenous proteolysis, also caused a biphasic extraction of MBP.	metal salts	9-20	myelin basic protein	Homo sapiens	109-112
2439084-0	1987	Covalent linkage of phosphoinositides to myelin basic protein: in vitro incorporation of [32P] phosphoinositides to myelin basic protein.	[32p] phosphoinositides	89-112	myelin basic protein	Homo sapiens	41-61
2439084-0	1987	Covalent linkage of phosphoinositides to myelin basic protein: in vitro incorporation of [32P] phosphoinositides to myelin basic protein.	[32p] phosphoinositides	89-112	myelin basic protein	Homo sapiens	116-136
2439084-1	1987	We have previously reported that the covalent attachment of phosphoinositides to myelin basic protein (MBP) occurs both in vivo and in vitro [Smith, R. A. et al.	Phosphatidylinositols	60-77	myelin basic protein	Homo sapiens	81-101
2439084-1	1987	We have previously reported that the covalent attachment of phosphoinositides to myelin basic protein (MBP) occurs both in vivo and in vitro [Smith, R. A. et al.	Phosphatidylinositols	60-77	myelin basic protein	Homo sapiens	103-106
3472249-1	1987	Major basic protein (MBP), the core of the eosinophil granule, is a potent toxin for parasites and mammalian cells; it also causes histamine release from mast cells and basophils.	Histamine	131-140	myelin basic protein	Homo sapiens	0-19
2439084-7	1987	Phosphoinositidation of MBP was also detected when [32P] phosphoinositides were incubated with myelin pretreated with Triton X-100 and EGTA.	Phosphorus-32	51-56	myelin basic protein	Homo sapiens	24-27
2439084-7	1987	Phosphoinositidation of MBP was also detected when [32P] phosphoinositides were incubated with myelin pretreated with Triton X-100 and EGTA.	Phosphatidylinositols	57-74	myelin basic protein	Homo sapiens	24-27
2439084-7	1987	Phosphoinositidation of MBP was also detected when [32P] phosphoinositides were incubated with myelin pretreated with Triton X-100 and EGTA.	Octoxynol	118-130	myelin basic protein	Homo sapiens	24-27
2439084-7	1987	Phosphoinositidation of MBP was also detected when [32P] phosphoinositides were incubated with myelin pretreated with Triton X-100 and EGTA.	Egtazic Acid	135-139	myelin basic protein	Homo sapiens	24-27
2439084-8	1987	Less than 10% of this covalent linkage of phosphoinositides to MBP survived after acidic treatment (0.1 N HCl at 37 degrees C for 10 min).	Phosphatidylinositols	42-59	myelin basic protein	Homo sapiens	63-66
2439084-8	1987	Less than 10% of this covalent linkage of phosphoinositides to MBP survived after acidic treatment (0.1 N HCl at 37 degrees C for 10 min).	Hydrochloric Acid	106-109	myelin basic protein	Homo sapiens	63-66
2437924-3	1987	Analysis of the sites of phosphorylation of the component 1 of human MBP, the most cationic species, catalyzed by a purified Ca2+-activated and phospholipid-dependent protein kinase and cAMP-dependent protein kinase revealed that although these protein kinases could incorporate approximately 6 and 4 mol 32P, respectively, into MBP, none of the potential sites were located within the middle domain.	Cyclic AMP	186-190	myelin basic protein	Homo sapiens	69-72
2437924-3	1987	Analysis of the sites of phosphorylation of the component 1 of human MBP, the most cationic species, catalyzed by a purified Ca2+-activated and phospholipid-dependent protein kinase and cAMP-dependent protein kinase revealed that although these protein kinases could incorporate approximately 6 and 4 mol 32P, respectively, into MBP, none of the potential sites were located within the middle domain.	Phosphorus-32	305-308	myelin basic protein	Homo sapiens	69-72
3472249-1	1987	Major basic protein (MBP), the core of the eosinophil granule, is a potent toxin for parasites and mammalian cells; it also causes histamine release from mast cells and basophils.	Histamine	131-140	myelin basic protein	Homo sapiens	21-24
2434489-0	1987	Effect of myelin basic protein on the thermotropic behavior of aqueous dispersions of neutral and anionic glycosphingolipids and their mixtures with dipalmitoylphosphatidylcholine.	Glycosphingolipids	106-124	myelin basic protein	Homo sapiens	10-30
2441743-0	1987	Myelin basic protein binds heme at a specific site near the tryptophan residue.	Heme	27-31	myelin basic protein	Homo sapiens	0-20
2441743-0	1987	Myelin basic protein binds heme at a specific site near the tryptophan residue.	Tryptophan	60-70	myelin basic protein	Homo sapiens	0-20
2441743-1	1987	Fluorescence of the single tryptophan residue in myelin basic protein (MBP) was excited directly at 295 nm (red-edge excitation) or at 278 nm which allows, in addition, indirect excitation by resonance energy transfer (RET) from any nearby tyrosine residues.	Tryptophan	27-37	myelin basic protein	Homo sapiens	49-69
2441743-1	1987	Fluorescence of the single tryptophan residue in myelin basic protein (MBP) was excited directly at 295 nm (red-edge excitation) or at 278 nm which allows, in addition, indirect excitation by resonance energy transfer (RET) from any nearby tyrosine residues.	Tryptophan	27-37	myelin basic protein	Homo sapiens	71-74
2441743-1	1987	Fluorescence of the single tryptophan residue in myelin basic protein (MBP) was excited directly at 295 nm (red-edge excitation) or at 278 nm which allows, in addition, indirect excitation by resonance energy transfer (RET) from any nearby tyrosine residues.	Tyrosine	240-248	myelin basic protein	Homo sapiens	49-69
2441743-1	1987	Fluorescence of the single tryptophan residue in myelin basic protein (MBP) was excited directly at 295 nm (red-edge excitation) or at 278 nm which allows, in addition, indirect excitation by resonance energy transfer (RET) from any nearby tyrosine residues.	Tyrosine	240-248	myelin basic protein	Homo sapiens	71-74
2441743-5	1987	This suggests that the mechanism of quenching now includes static in addition to collisional processes and thus that heme has a relatively high affinity for MBP.	Heme	117-121	myelin basic protein	Homo sapiens	157-160
2441743-7	1987	The hydrophobic fluorescent probe 4,4"-bis[1-(phenylamino)-8-naphthalenesulfonate] [bis(ANS)] binds to MBP less avidly (Kd = 10(-7) M) and is rapidly displaced by chloroheme (Ki = 2 X 10(-8) M).	4,4"-bis[1-(phenylamino)-8-naphthalenesulfonate	34-81	myelin basic protein	Homo sapiens	103-106
2441743-7	1987	The hydrophobic fluorescent probe 4,4"-bis[1-(phenylamino)-8-naphthalenesulfonate] [bis(ANS)] binds to MBP less avidly (Kd = 10(-7) M) and is rapidly displaced by chloroheme (Ki = 2 X 10(-8) M).	5,5'-bis(8-(phenylamino)-1-naphthalenesulfonate)	84-92	myelin basic protein	Homo sapiens	103-106
2441743-7	1987	The hydrophobic fluorescent probe 4,4"-bis[1-(phenylamino)-8-naphthalenesulfonate] [bis(ANS)] binds to MBP less avidly (Kd = 10(-7) M) and is rapidly displaced by chloroheme (Ki = 2 X 10(-8) M).	chloroheme	163-173	myelin basic protein	Homo sapiens	103-106
2441743-8	1987	The affinities of bis(ANS) and heme for MBP, along with the fluorescent amino acid quenching data, demonstrate that a subfraction of MBP molecules contain considerable structural specificity, implying stable long-range interactions in the molecule.	5,5'-bis(8-(phenylamino)-1-naphthalenesulfonate)	18-26	myelin basic protein	Homo sapiens	40-43
2441743-8	1987	The affinities of bis(ANS) and heme for MBP, along with the fluorescent amino acid quenching data, demonstrate that a subfraction of MBP molecules contain considerable structural specificity, implying stable long-range interactions in the molecule.	5,5'-bis(8-(phenylamino)-1-naphthalenesulfonate)	18-26	myelin basic protein	Homo sapiens	133-136
2441743-8	1987	The affinities of bis(ANS) and heme for MBP, along with the fluorescent amino acid quenching data, demonstrate that a subfraction of MBP molecules contain considerable structural specificity, implying stable long-range interactions in the molecule.	Heme	31-35	myelin basic protein	Homo sapiens	40-43
2441743-8	1987	The affinities of bis(ANS) and heme for MBP, along with the fluorescent amino acid quenching data, demonstrate that a subfraction of MBP molecules contain considerable structural specificity, implying stable long-range interactions in the molecule.	Heme	31-35	myelin basic protein	Homo sapiens	133-136
2433582-5	1987	The level of antibody to cerebroside correlated best with the number of injections of vaccine, but like antibody to myelin basic protein, the antibody to cerebroside was present in the cerebrospinal fluid of patients with major complications.	Cerebrosides	154-165	myelin basic protein	Homo sapiens	116-136
2434489-0	1987	Effect of myelin basic protein on the thermotropic behavior of aqueous dispersions of neutral and anionic glycosphingolipids and their mixtures with dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	149-179	myelin basic protein	Homo sapiens	10-30
2434489-3	1987	The thermotropic behavior of anionic glycosphingolipids is considerably perturbed by MBP.	Glycosphingolipids	37-55	myelin basic protein	Homo sapiens	85-88
2434489-4	1987	The transition temperature of gangliosides increases in the presence of MBP, whereas that of sulfatide decreases.	Gangliosides	30-42	myelin basic protein	Homo sapiens	72-75
2434489-5	1987	The enthalpy of the transition of anionic glycosphingolipids increases markedly in the presence of MBP.	Glycosphingolipids	42-60	myelin basic protein	Homo sapiens	99-102
2434489-10	1987	The proportion of MBP required to produce the maximal changes is greater the greater the complexity of the glycosphingolipids polar head group.	Glycosphingolipids	107-125	myelin basic protein	Homo sapiens	18-21
2430621-0	1986	Modulation of myelin basic protein-induced aggregation and fusion of liposomes by cholesterol, aliphatic aldehydes and alkanes.	Cholesterol	82-93	myelin basic protein	Homo sapiens	14-34
2433157-0	1987	Interaction of myelin basic protein with the different components of the ATP,Mg-dependent protein phosphatase system.	Adenosine Triphosphate	73-76	myelin basic protein	Homo sapiens	15-35
2433157-1	1987	Myelin basic protein (MBP) reduces the amount of phosphatase activity produced in the kinase FA-mediated activation of the ATP,Mg-dependent phosphatase.	Adenosine Triphosphate	123-126	myelin basic protein	Homo sapiens	0-20
2433157-1	1987	Myelin basic protein (MBP) reduces the amount of phosphatase activity produced in the kinase FA-mediated activation of the ATP,Mg-dependent phosphatase.	Adenosine Triphosphate	123-126	myelin basic protein	Homo sapiens	22-25
2433157-4	1987	These observations point to a regulatory role for MBP in the reversible activation of the ATP,Mg-dependent protein phosphatase by kinase FA.	Adenosine Triphosphate	90-93	myelin basic protein	Homo sapiens	50-53
3630520-1	1987	The substrate specificity of purified human protein kinase C was modulated by 12-O-tetradecanoyl-4 beta-phorbol-13-acetate (TPA), dioleoylglycerol, arachidonic acid and lipid A when histone type III-S and myelin basic protein were used as phosphate acceptors.	12-o-tetradecanoyl-4 beta-phorbol-13-acetate	78-122	myelin basic protein	Homo sapiens	205-225
3549020-7	1986	The thermotropic behavior of GSLs is considerably perturbed by myelin basic protein.	Glycosphingolipids	29-33	myelin basic protein	Homo sapiens	63-83
2430621-0	1986	Modulation of myelin basic protein-induced aggregation and fusion of liposomes by cholesterol, aliphatic aldehydes and alkanes.	aliphatic aldehydes	95-114	myelin basic protein	Homo sapiens	14-34
2430621-0	1986	Modulation of myelin basic protein-induced aggregation and fusion of liposomes by cholesterol, aliphatic aldehydes and alkanes.	Alkanes	119-126	myelin basic protein	Homo sapiens	14-34
2430621-1	1986	The effect of cholesterol on myelin basic protein-induced aggregation of zwitterionic phospholipid vesicles was studied by turbidimetry, quasi-elastic light scattering and centrifugation techniques.	Cholesterol	14-25	myelin basic protein	Homo sapiens	29-49
2430621-1	1986	The effect of cholesterol on myelin basic protein-induced aggregation of zwitterionic phospholipid vesicles was studied by turbidimetry, quasi-elastic light scattering and centrifugation techniques.	Phospholipids	86-98	myelin basic protein	Homo sapiens	29-49
2430621-6	1986	Palmitoyl aldehyde and eicosane, substances resembling products of lipid degradation, increase myelin basic protein promoted fusion of vesicles.	hexadecanal	0-18	myelin basic protein	Homo sapiens	95-115
2430621-6	1986	Palmitoyl aldehyde and eicosane, substances resembling products of lipid degradation, increase myelin basic protein promoted fusion of vesicles.	eicosane	23-31	myelin basic protein	Homo sapiens	95-115
2430621-8	1986	In the presence of cholesterol, myelin basic protein-induced fusion of the liposomes becomes much more sensitive to the presence of aliphatic aldehydes or alkanes.	Cholesterol	19-30	myelin basic protein	Homo sapiens	32-52
2430621-8	1986	In the presence of cholesterol, myelin basic protein-induced fusion of the liposomes becomes much more sensitive to the presence of aliphatic aldehydes or alkanes.	aliphatic aldehydes	132-151	myelin basic protein	Homo sapiens	32-52
2430621-8	1986	In the presence of cholesterol, myelin basic protein-induced fusion of the liposomes becomes much more sensitive to the presence of aliphatic aldehydes or alkanes.	Alkanes	155-162	myelin basic protein	Homo sapiens	32-52
2433962-1	1986	A new two-dimensional polyacrylamide gel electrophoresis (PAGE) system with minislab gel apparatus was devised for the rapid (4 h) analysis of peptide fragments derived from the enzymic digestion of myelin basic protein (MBP).	polyacrylamide	22-36	myelin basic protein	Homo sapiens	199-219
2439449-0	1986	Inhibition of binding of hamster antibody to myelin basic protein by a synthetic triproline-containing peptide from JC virus T-antigen.	triproline	81-91	myelin basic protein	Homo sapiens	45-65
2439449-5	1986	These results suggest that the triproline region of MBP can be immunogenic in hamsters, and support the concept that a conformation of the MBP triproline region is shared with certain of its viral homologues.	triproline	31-41	myelin basic protein	Homo sapiens	52-55
2439449-5	1986	These results suggest that the triproline region of MBP can be immunogenic in hamsters, and support the concept that a conformation of the MBP triproline region is shared with certain of its viral homologues.	triproline	31-41	myelin basic protein	Homo sapiens	139-142
2439449-5	1986	These results suggest that the triproline region of MBP can be immunogenic in hamsters, and support the concept that a conformation of the MBP triproline region is shared with certain of its viral homologues.	triproline	143-153	myelin basic protein	Homo sapiens	52-55
2439449-5	1986	These results suggest that the triproline region of MBP can be immunogenic in hamsters, and support the concept that a conformation of the MBP triproline region is shared with certain of its viral homologues.	triproline	143-153	myelin basic protein	Homo sapiens	139-142
2439449-7	1986	While significant increases in response compared to prebleed levels were observed in about one-fourth of the sera, some of them showed similar increases in binding to other basic proteins such as histones, and the binding to MBP was not inhibited by the triproline-containing decapeptide.	decapeptide	276-287	myelin basic protein	Homo sapiens	225-228
2433962-1	1986	A new two-dimensional polyacrylamide gel electrophoresis (PAGE) system with minislab gel apparatus was devised for the rapid (4 h) analysis of peptide fragments derived from the enzymic digestion of myelin basic protein (MBP).	polyacrylamide	22-36	myelin basic protein	Homo sapiens	221-224
2433962-5	1986	By contrast, acid-urea 15% PAGE separated MBP peptides by both charge and size.	acid-urea	13-22	myelin basic protein	Homo sapiens	42-45
2433962-6	1986	A two-dimensional system of 5% PAGE followed by sodium dodecylsulfate 15% PAGE (Laemmli) was used to resolve MBP fragments from pepsin and cathepsin D digests; this analysis indicated that cathodic mobilities could be predicted by the ratio of basic to acidic amino acids in each peptide.	Sodium Dodecyl Sulfate	48-69	myelin basic protein	Homo sapiens	109-112
2431334-6	1986	Degradation of MBP was inhibited by FOY305 (camostat mesilate), Trasylol, and Leupeptin, but not a specific calcium-activated neutral protease inhibitor, E-64-a.	camostat	36-42	myelin basic protein	Homo sapiens	15-18
2431910-1	1986	The interaction between myelin basic protein (MBP) and G-actin was studied under nonpolymerizing conditions, i.e.,2mM HEPES, pH 7.5, 0.1 mM CaCl2 and 0.2 mM ATP.	HEPES	118-123	myelin basic protein	Homo sapiens	24-44
2431910-1	1986	The interaction between myelin basic protein (MBP) and G-actin was studied under nonpolymerizing conditions, i.e.,2mM HEPES, pH 7.5, 0.1 mM CaCl2 and 0.2 mM ATP.	HEPES	118-123	myelin basic protein	Homo sapiens	46-49
2431910-1	1986	The interaction between myelin basic protein (MBP) and G-actin was studied under nonpolymerizing conditions, i.e.,2mM HEPES, pH 7.5, 0.1 mM CaCl2 and 0.2 mM ATP.	Calcium Chloride	140-145	myelin basic protein	Homo sapiens	24-44
2431910-1	1986	The interaction between myelin basic protein (MBP) and G-actin was studied under nonpolymerizing conditions, i.e.,2mM HEPES, pH 7.5, 0.1 mM CaCl2 and 0.2 mM ATP.	Adenosine Triphosphate	157-160	myelin basic protein	Homo sapiens	24-44
2431910-1	1986	The interaction between myelin basic protein (MBP) and G-actin was studied under nonpolymerizing conditions, i.e.,2mM HEPES, pH 7.5, 0.1 mM CaCl2 and 0.2 mM ATP.	Adenosine Triphosphate	157-160	myelin basic protein	Homo sapiens	46-49
2431910-2	1986	Fluorescence studies using pyrenyl-actin and the measurements of ATP hydrolysis rate show that MBP induces changes in the structure of the actin monomer similar to those occurring during polymerization by salt.	Adenosine Triphosphate	65-68	myelin basic protein	Homo sapiens	95-98
2431910-2	1986	Fluorescence studies using pyrenyl-actin and the measurements of ATP hydrolysis rate show that MBP induces changes in the structure of the actin monomer similar to those occurring during polymerization by salt.	Salts	205-209	myelin basic protein	Homo sapiens	95-98
2431334-6	1986	Degradation of MBP was inhibited by FOY305 (camostat mesilate), Trasylol, and Leupeptin, but not a specific calcium-activated neutral protease inhibitor, E-64-a.	camostat	44-61	myelin basic protein	Homo sapiens	15-18
2431334-6	1986	Degradation of MBP was inhibited by FOY305 (camostat mesilate), Trasylol, and Leupeptin, but not a specific calcium-activated neutral protease inhibitor, E-64-a.	leupeptin	78-87	myelin basic protein	Homo sapiens	15-18
2431909-1	1986	Myelin basic protein (MBP) binds to both skeletal muscle and brain tropomyosin resulting in the formation of paracrystalline tactoids in the absence of divalent cations and at neutral pH.	paracrystalline tactoids	109-133	myelin basic protein	Homo sapiens	0-20
2424413-8	1986	The in vitro response of patients with DIP to myelin basic protein (7/30) was not significantly different from that of the control population (16/44).	dip	39-42	myelin basic protein	Homo sapiens	46-66
2420937-3	1986	Myelin basic protein is solubilized by extraction in acetate buffer, pH 4.5.	Acetates	53-60	myelin basic protein	Homo sapiens	0-20
2431909-1	1986	Myelin basic protein (MBP) binds to both skeletal muscle and brain tropomyosin resulting in the formation of paracrystalline tactoids in the absence of divalent cations and at neutral pH.	paracrystalline tactoids	109-133	myelin basic protein	Homo sapiens	22-25
2420275-2	1986	Carbon-13 and phosphorus-31 nuclear magnetic resonance spectroscopy has been used to study this interaction by examining spectral consequences of additions of MBP to membrane preparations of the negatively charged lipid phosphatidylglycerol (PG).	Phosphatidylglycerols	242-244	myelin basic protein	Homo sapiens	159-162
2421722-2	1986	We now report that the level of D-aspartate in human brains is higher in purified myelin than in white matter and is even higher in the myelin basic protein fraction.	D-Aspartic Acid	32-43	myelin basic protein	Homo sapiens	136-156
2420275-2	1986	Carbon-13 and phosphorus-31 nuclear magnetic resonance spectroscopy has been used to study this interaction by examining spectral consequences of additions of MBP to membrane preparations of the negatively charged lipid phosphatidylglycerol (PG).	Phosphatidylglycerols	220-240	myelin basic protein	Homo sapiens	159-162
2420275-4	1986	At intermediate MBP/PG ratios, two components in slow exchange on the NMR time scale (bulk PG and a protein-induced PG domain) were observed for the 13C resonance of the head group carbon atom adjacent to phosphate.	13c	149-152	myelin basic protein	Homo sapiens	16-19
2420275-4	1986	At intermediate MBP/PG ratios, two components in slow exchange on the NMR time scale (bulk PG and a protein-induced PG domain) were observed for the 13C resonance of the head group carbon atom adjacent to phosphate.	Carbon	181-187	myelin basic protein	Homo sapiens	16-19
2420275-4	1986	At intermediate MBP/PG ratios, two components in slow exchange on the NMR time scale (bulk PG and a protein-induced PG domain) were observed for the 13C resonance of the head group carbon atom adjacent to phosphate.	Phosphates	205-214	myelin basic protein	Homo sapiens	16-19
2420275-5	1986	These results, and other spectral evidence, suggested that head groups in free PG vesicles are motionally restricted by intermolecular interactions which are disrupted by competition with MBP Lys and Arg positively charged side chains.	Lysine	192-195	myelin basic protein	Homo sapiens	188-191
3510271-8	1986	All BP components from trout PNS and CNS myelins bound to antibodies against human myelin basic protein.	Benzo(a)pyrene	4-6	myelin basic protein	Homo sapiens	83-103
2420429-2	1986	The purposes of this study were to determine whether anti-MBP antibodies are present in increased titer in CSF of MS patients with exacerbations, and whether they can be suppressed by the administration of immunosuppressive dosages of methylprednisolone (MP).	Methylprednisolone	235-253	myelin basic protein	Homo sapiens	58-61
2420429-2	1986	The purposes of this study were to determine whether anti-MBP antibodies are present in increased titer in CSF of MS patients with exacerbations, and whether they can be suppressed by the administration of immunosuppressive dosages of methylprednisolone (MP).	Methylprednisolone	255-257	myelin basic protein	Homo sapiens	58-61
3516179-6	1986	Evidence for this suggestion has been gathered from studies of the myelin basic protein, a water-soluble protein with a number of hydrophobic residues.	Water	91-96	myelin basic protein	Homo sapiens	67-87
3532688-2	1986	Since this sequence functions as a phosphate acceptor site in MBP, expression of a competing T-antigen sequence in oligodendroglia might adversely affect their ability to post-translationally process MBP and thus to maintain myelin.	Phosphates	35-44	myelin basic protein	Homo sapiens	62-65
3532688-2	1986	Since this sequence functions as a phosphate acceptor site in MBP, expression of a competing T-antigen sequence in oligodendroglia might adversely affect their ability to post-translationally process MBP and thus to maintain myelin.	Phosphates	35-44	myelin basic protein	Homo sapiens	200-203
2418825-0	1986	Myelin basic protein ability to organize lipid bilayers: structural transition in bilayers of lysophosphatidylcholine micelles.	Lysophosphatidylcholines	94-117	myelin basic protein	Homo sapiens	0-20
2418825-1	1986	Myelin basic protein isolated by a single step with the cationic detergent cethyltrimethylammonium bromide in a lipid-bound form is able to induce structural transition of lysophosphatydilcholine micelles into multi-laminar vesicles.	cethyltrimethylammonium bromide	75-106	myelin basic protein	Homo sapiens	0-20
2418825-1	1986	Myelin basic protein isolated by a single step with the cationic detergent cethyltrimethylammonium bromide in a lipid-bound form is able to induce structural transition of lysophosphatydilcholine micelles into multi-laminar vesicles.	lysophosphatydilcholine	172-195	myelin basic protein	Homo sapiens	0-20
2421004-1	1986	Some acidic lipids including sulfatide and phosphatidylinositol were found to increase greatly the rate of cathepsin D cleavage of the myelin basic protein.	Sulfoglycosphingolipids	29-38	myelin basic protein	Homo sapiens	135-155
2416809-4	1986	Although the fine specificities of the reagent antisera differed, competitive inhibition analyses with intact MBP revealed a cross-reactive determinant involving residues 99-100 (Thr-Pro).	Threonine	179-182	myelin basic protein	Homo sapiens	110-113
2416809-4	1986	Although the fine specificities of the reagent antisera differed, competitive inhibition analyses with intact MBP revealed a cross-reactive determinant involving residues 99-100 (Thr-Pro).	Proline	183-186	myelin basic protein	Homo sapiens	110-113
2421004-1	1986	Some acidic lipids including sulfatide and phosphatidylinositol were found to increase greatly the rate of cathepsin D cleavage of the myelin basic protein.	Phosphatidylinositols	43-63	myelin basic protein	Homo sapiens	135-155
2421004-8	1986	It is possible that the elevated levels of cathepsin D and sulfatide that have previously been found associated with multiple sclerosis plaques in vivo act in concert to bring about the rapid cleavage and subsequent loss of the myelin basic protein from these localized regions in the myelin sheath.	Sulfoglycosphingolipids	59-68	myelin basic protein	Homo sapiens	228-248
2418890-2	1985	The insertion of myelin basic protein into microemulsion droplets of sodium bis (2-ethylhexyl) sulfosuccinate (AOT) has been studied by quasi-elastic light scattering.	Dioctyl Sulfosuccinic Acid	69-109	myelin basic protein	Homo sapiens	17-37
2416887-0	1986	Myelin basic protein concentrations in the CSF of children receiving methotrexate.	Methotrexate	69-81	myelin basic protein	Homo sapiens	0-20
2418890-2	1985	The insertion of myelin basic protein into microemulsion droplets of sodium bis (2-ethylhexyl) sulfosuccinate (AOT) has been studied by quasi-elastic light scattering.	Dioctyl Sulfosuccinic Acid	111-114	myelin basic protein	Homo sapiens	17-37
2413893-0	1985	Aliphatic aldehydes promote myelin basic protein-induced fusion of phospholipid vesicles.	aliphatic aldehydes	0-19	myelin basic protein	Homo sapiens	28-48
2413893-1	1985	Myelin basic protein induces slow and limited fusion of phospholipid vesicles composed of a mixture of phosphatidylcholine and phosphatidylethanolamine.	Phospholipids	56-68	myelin basic protein	Homo sapiens	0-20
2413893-1	1985	Myelin basic protein induces slow and limited fusion of phospholipid vesicles composed of a mixture of phosphatidylcholine and phosphatidylethanolamine.	Phosphatidylcholines	103-122	myelin basic protein	Homo sapiens	0-20
2413893-1	1985	Myelin basic protein induces slow and limited fusion of phospholipid vesicles composed of a mixture of phosphatidylcholine and phosphatidylethanolamine.	phosphatidylethanolamine	127-151	myelin basic protein	Homo sapiens	0-20
2413893-2	1985	Addition of palmitoyl aldehyde to these vesicles dramatically increases their ability to fuse in the presence of myelin basic protein.	hexadecanal	12-30	myelin basic protein	Homo sapiens	113-133
2413893-3	1985	Compared to aliphatic aldehydes, fatty acids are much less potent promoters of myelin basic protein-induced membrane fusion.	Fatty Acids	33-44	myelin basic protein	Homo sapiens	79-99
2413893-4	1985	The ability of aliphatic aldehydes to promote myelin basic protein-induced membrane fusion may be of relevance to myelin structure and function and, particularly, to the pathology of demyelinating diseases such as multiple sclerosis.	aliphatic aldehydes	15-34	myelin basic protein	Homo sapiens	46-66
4026327-2	1985	The neutral binding protein (pI 7.0), which has a high glycine content, is an analog of mammalian liver MBP (F-I).	Glycine	55-62	myelin basic protein	Homo sapiens	104-107
2412585-0	1985	Interaction of myelin basic protein with gangliosides and ganglioside-phospholipid mixtures.	Gangliosides	41-53	myelin basic protein	Homo sapiens	15-35
2412585-0	1985	Interaction of myelin basic protein with gangliosides and ganglioside-phospholipid mixtures.	Gangliosides	41-52	myelin basic protein	Homo sapiens	15-35
2412585-0	1985	Interaction of myelin basic protein with gangliosides and ganglioside-phospholipid mixtures.	Phospholipids	70-82	myelin basic protein	Homo sapiens	15-35
2412585-1	1985	The interaction of myelin basic protein with monosialoganglioside GM1 was investigated.	sialogangliosides	45-65	myelin basic protein	Homo sapiens	19-39
2412585-1	1985	The interaction of myelin basic protein with monosialoganglioside GM1 was investigated.	G(M1) Ganglioside	66-69	myelin basic protein	Homo sapiens	19-39
2412585-3	1985	In mixtures of the monosialoganglioside with phosphatidylcholine, the myelin basic protein induces phase separation of the lipids as inferred from differential scanning calorimetry experiments.	sialogangliosides	19-39	myelin basic protein	Homo sapiens	70-90
2412585-3	1985	In mixtures of the monosialoganglioside with phosphatidylcholine, the myelin basic protein induces phase separation of the lipids as inferred from differential scanning calorimetry experiments.	Phosphatidylcholines	45-64	myelin basic protein	Homo sapiens	70-90
2411291-0	1985	Myelin basic protein induces hexagonal phase formation in dispersions of diacylphosphatidic acid.	diacylphosphatidic acid	73-96	myelin basic protein	Homo sapiens	0-20
2411868-2	1985	The incorporation of tritium from NaB3H4 into myelin proteins was confirmed by reaction with purified components of myelin basic protein or with lipophilin, a purified fraction of proteolipid protein.	Tritium	21-28	myelin basic protein	Homo sapiens	116-136
2411868-2	1985	The incorporation of tritium from NaB3H4 into myelin proteins was confirmed by reaction with purified components of myelin basic protein or with lipophilin, a purified fraction of proteolipid protein.	nab3h4	34-40	myelin basic protein	Homo sapiens	116-136
2411868-3	1985	From the extent of tritium incorporation into the purified proteins, it is estimated that approximately 0.2 mol of tritium is incorporated/mol of myelin basic protein and approximately 0.4 mol of tritium/mol of proteolipid protein.	Tritium	115-122	myelin basic protein	Homo sapiens	146-166
2411868-3	1985	From the extent of tritium incorporation into the purified proteins, it is estimated that approximately 0.2 mol of tritium is incorporated/mol of myelin basic protein and approximately 0.4 mol of tritium/mol of proteolipid protein.	Tritium	115-122	myelin basic protein	Homo sapiens	146-166
2410064-7	1985	Radioimmunoassay for MBP was positive in 5/9 Eo-type and 0/10 neutrophil-macrophage ("GM-type") colonies, with a mean level (nanogram/colony) of 11.6 +/- 4.2 per Eo-type colony; four of the latter colonies were doubly positive for both histamine and MBP.	Histamine	236-245	myelin basic protein	Homo sapiens	21-24
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Glycine	12-15	myelin basic protein	Homo sapiens	58-78
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Glycine	12-15	myelin basic protein	Homo sapiens	80-83
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Glycine	12-15	myelin basic protein	Homo sapiens	142-145
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Arginine	16-19	myelin basic protein	Homo sapiens	58-78
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Arginine	16-19	myelin basic protein	Homo sapiens	80-83
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Arginine	16-19	myelin basic protein	Homo sapiens	142-145
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Alanine	20-23	myelin basic protein	Homo sapiens	58-78
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Alanine	20-23	myelin basic protein	Homo sapiens	80-83
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Alanine	20-23	myelin basic protein	Homo sapiens	142-145
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Serine	24-27	myelin basic protein	Homo sapiens	58-78
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Serine	24-27	myelin basic protein	Homo sapiens	80-83
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Serine	24-27	myelin basic protein	Homo sapiens	142-145
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Aspartic Acid	28-31	myelin basic protein	Homo sapiens	58-78
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Aspartic Acid	28-31	myelin basic protein	Homo sapiens	80-83
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Aspartic Acid	28-31	myelin basic protein	Homo sapiens	142-145
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Tyrosine	32-35	myelin basic protein	Homo sapiens	58-78
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Tyrosine	32-35	myelin basic protein	Homo sapiens	80-83
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Tyrosine	32-35	myelin basic protein	Homo sapiens	142-145
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Lysine	36-39	myelin basic protein	Homo sapiens	58-78
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Lysine	36-39	myelin basic protein	Homo sapiens	80-83
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Lysine	36-39	myelin basic protein	Homo sapiens	142-145
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Serine	40-43	myelin basic protein	Homo sapiens	58-78
2408668-0	1985	Interaction of myelin basic protein and polylysine with synthetic species of cerebroside sulfate.	cerebroside sulfate	77-96	myelin basic protein	Homo sapiens	15-35
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Serine	40-43	myelin basic protein	Homo sapiens	80-83
2412548-3	1985	The peptide Gly-Arg-Ala-Ser-Asp-Tyr-Lys-Ser, derived from myelin basic protein (MBP), is part of an epitope to monoclonal antibodies to human MBP.	Serine	40-43	myelin basic protein	Homo sapiens	142-145
2411747-1	1985	A reversed-phase high-performance liquid chromatography (HPLC) system was developed to obtain individual tryptic peptides of myelin basic protein (BP).	Peptides	113-121	myelin basic protein	Homo sapiens	125-145
2411747-0	1985	Isolation of tryptic peptides of myelin basic protein by reversed-phase high-performance liquid chromatography.	Peptides	21-29	myelin basic protein	Homo sapiens	33-53
2408668-1	1985	The effect of myelin basic protein on the myelin lipid cerebroside sulfate was studied by differential scanning calorimetry and use of the fatty acid spin label, 16-S-SL, in order to determine (i) the effect of basic protein on the metastable phase behavior experienced by this lipid, and (ii) to determine if basic protein perturbs the lipid packing as it does with some acidic phospholipids.	cerebroside sulfate	55-74	myelin basic protein	Homo sapiens	14-34
2408611-9	1985	With b-MBP, but not p-MBP, specific interactions are observed at the residue tyrosine-135, which is part of the epitopic sequence.	Tyrosine	77-85	myelin basic protein	Homo sapiens	7-10
6510876-9	1984	At rest, compared with control measurements after saline, these plasma concentrations of verapamil were associated with linear decreases in systemic vascular resistance (maximum delta SVR -720 dyne X s X cm-5/m2; p less than 0.01) and blood pressure (maximum delta MBP -8 mmHg; p less than 0.05) and linear increases in cardiac index (maximum delta CI +0.4 l/min/m2; p less than 0.05) and in pulmonary artery occluded pressure (maximum delta PAOP +3 mmHg; p less than 0.05).	Verapamil	89-98	myelin basic protein	Homo sapiens	265-268
2580064-0	1985	High-dose methotrexate-induced neurotoxicity associated with elevation of CSF myelin basic protein.	Methotrexate	10-22	myelin basic protein	Homo sapiens	78-98
2410023-4	1985	The enhanced fluorescence and shift in the emission maximum of 6-(p-toluidino)-2-naphthalenesulfonate when bound to myelin basic protein are consistent with the presence of at least one hydrophobic region in the molecule.	6-(p-toluidino)-2-naphthalenesulfonate	63-101	myelin basic protein	Homo sapiens	116-136
2579646-0	1985	The role of charge microheterogeneity of human myelin basic protein in the formation of phosphatidylglycerol multilayers.	Phosphatidylglycerols	88-108	myelin basic protein	Homo sapiens	47-67
2982051-3	1985	A single dose of MK-421 produced a significant fall in MBP from 2 to 24 hours post-drug.	Enalapril	17-23	myelin basic protein	Homo sapiens	55-58
6502227-8	1984	Cells plated on polylysine-coated aclar dishes attached, emanated numerous, pleomorphic processes, and expressed galactocerebroside and myelin basic protein, characteristic markers for oligodendrocytes.	Polylysine	16-26	myelin basic protein	Homo sapiens	136-156
6084518-0	1984	Interaction of myelin basic protein with micelles of dodecylphosphocholine.	dodecylphosphocholine	53-74	myelin basic protein	Homo sapiens	15-35
6084518-1	1984	Interactions of myelin basic protein (MBP) and peptides derived from it with micelles of dodecylphosphocholine (DPC) and perdeuterated DPC have been studied by proton nuclear magnetic resonance (NMR) at 400 MHz and by circular dichroism (CD).	dodecylphosphocholine	89-110	myelin basic protein	Homo sapiens	16-36
6084518-1	1984	Interactions of myelin basic protein (MBP) and peptides derived from it with micelles of dodecylphosphocholine (DPC) and perdeuterated DPC have been studied by proton nuclear magnetic resonance (NMR) at 400 MHz and by circular dichroism (CD).	dodecylphosphocholine	89-110	myelin basic protein	Homo sapiens	38-41
6084518-1	1984	Interactions of myelin basic protein (MBP) and peptides derived from it with micelles of dodecylphosphocholine (DPC) and perdeuterated DPC have been studied by proton nuclear magnetic resonance (NMR) at 400 MHz and by circular dichroism (CD).	dodecylphosphocholine	112-115	myelin basic protein	Homo sapiens	16-36
6084518-1	1984	Interactions of myelin basic protein (MBP) and peptides derived from it with micelles of dodecylphosphocholine (DPC) and perdeuterated DPC have been studied by proton nuclear magnetic resonance (NMR) at 400 MHz and by circular dichroism (CD).	dodecylphosphocholine	112-115	myelin basic protein	Homo sapiens	38-41
6084518-1	1984	Interactions of myelin basic protein (MBP) and peptides derived from it with micelles of dodecylphosphocholine (DPC) and perdeuterated DPC have been studied by proton nuclear magnetic resonance (NMR) at 400 MHz and by circular dichroism (CD).	dodecylphosphocholine	135-138	myelin basic protein	Homo sapiens	16-36
6084518-1	1984	Interactions of myelin basic protein (MBP) and peptides derived from it with micelles of dodecylphosphocholine (DPC) and perdeuterated DPC have been studied by proton nuclear magnetic resonance (NMR) at 400 MHz and by circular dichroism (CD).	dodecylphosphocholine	135-138	myelin basic protein	Homo sapiens	38-41
6084518-2	1984	When MBP binds to DPC micelles, it acquires about 18% alpha-helicity.	dodecylphosphocholine	18-21	myelin basic protein	Homo sapiens	5-8
6084518-3	1984	The CD spectra of various peptides derived by cleavage of MBP indicate that a major alpha-helical region occurs in residues 85-99 just before the sequence of three prolyl residues 100-102.	Peptide oostatic hormone	164-170	myelin basic protein	Homo sapiens	58-61
6084518-4	1984	From line broadenings by fatty acid spin-labels in the micelles and from changes in chemical shifts, the NMR data identify specific residues in MBP that participate in lipid binding.	Fatty Acids	25-35	myelin basic protein	Homo sapiens	144-147
6205122-1	1984	Polypeptides arising from neutral in vitro proteolysis of myelin basic protein (MBP) of human brain were evaluated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.	Sodium Dodecyl Sulfate	118-140	myelin basic protein	Homo sapiens	80-83
6206154-1	1984	Major basic protein (MBP), an arginine-rich basic polypeptide that constitutes the crystalloid core of the large specific eosinophil granule, has previously been shown to stimulate noncytolytic histamine release from human basophils and rat mast cells by an IgE-independent mechanism.	Histamine	194-203	myelin basic protein	Homo sapiens	0-19
6206154-1	1984	Major basic protein (MBP), an arginine-rich basic polypeptide that constitutes the crystalloid core of the large specific eosinophil granule, has previously been shown to stimulate noncytolytic histamine release from human basophils and rat mast cells by an IgE-independent mechanism.	Histamine	194-203	myelin basic protein	Homo sapiens	21-24
6206154-4	1984	Incubation of basophil-containing human mononuclear cells with the individual column fractions demonstrated that histamine release occurred only with the fractions that contained MBP.	Histamine	113-122	myelin basic protein	Homo sapiens	179-182
6206154-8	1984	The distinct potency of MBP as a stimulus for histamine secretion from human basophils suggests that eosinophil release of MBP may be a specific event in the augmentation of immediate hypersensitivity reactions and other disorders characterized by eosinophilia.	Histamine	46-55	myelin basic protein	Homo sapiens	24-27
6206154-8	1984	The distinct potency of MBP as a stimulus for histamine secretion from human basophils suggests that eosinophil release of MBP may be a specific event in the augmentation of immediate hypersensitivity reactions and other disorders characterized by eosinophilia.	Histamine	46-55	myelin basic protein	Homo sapiens	123-126
6083470-0	1984	Format determinants of synthetic myelin basic protein peptide S82 mimicked by a mixture of synthetic peptides S8 and S79.	Peptides	101-109	myelin basic protein	Homo sapiens	33-53
6083471-1	1984	Two different kinds of immunosorbents were prepared that contained the synthetic myelin basic protein didecapeptide S82 (TTHYGSLPQKAQGHRDQDEG)--one coupled with AH-Sepharose 4B through hexanoate spacers to the C-terminal glycyl residue; the other, with CH-Sepharose 4B through hexanoate spacers to the N-terminal threonine residue.	Sepharose	164-173	myelin basic protein	Homo sapiens	81-101
6083471-1	1984	Two different kinds of immunosorbents were prepared that contained the synthetic myelin basic protein didecapeptide S82 (TTHYGSLPQKAQGHRDQDEG)--one coupled with AH-Sepharose 4B through hexanoate spacers to the C-terminal glycyl residue; the other, with CH-Sepharose 4B through hexanoate spacers to the N-terminal threonine residue.	hexanoic acid	185-194	myelin basic protein	Homo sapiens	81-101
6083471-1	1984	Two different kinds of immunosorbents were prepared that contained the synthetic myelin basic protein didecapeptide S82 (TTHYGSLPQKAQGHRDQDEG)--one coupled with AH-Sepharose 4B through hexanoate spacers to the C-terminal glycyl residue; the other, with CH-Sepharose 4B through hexanoate spacers to the N-terminal threonine residue.	glycyl	221-227	myelin basic protein	Homo sapiens	81-101
6083471-1	1984	Two different kinds of immunosorbents were prepared that contained the synthetic myelin basic protein didecapeptide S82 (TTHYGSLPQKAQGHRDQDEG)--one coupled with AH-Sepharose 4B through hexanoate spacers to the C-terminal glycyl residue; the other, with CH-Sepharose 4B through hexanoate spacers to the N-terminal threonine residue.	Sepharose	256-265	myelin basic protein	Homo sapiens	81-101
6083471-1	1984	Two different kinds of immunosorbents were prepared that contained the synthetic myelin basic protein didecapeptide S82 (TTHYGSLPQKAQGHRDQDEG)--one coupled with AH-Sepharose 4B through hexanoate spacers to the C-terminal glycyl residue; the other, with CH-Sepharose 4B through hexanoate spacers to the N-terminal threonine residue.	hexanoic acid	277-286	myelin basic protein	Homo sapiens	81-101
6083471-1	1984	Two different kinds of immunosorbents were prepared that contained the synthetic myelin basic protein didecapeptide S82 (TTHYGSLPQKAQGHRDQDEG)--one coupled with AH-Sepharose 4B through hexanoate spacers to the C-terminal glycyl residue; the other, with CH-Sepharose 4B through hexanoate spacers to the N-terminal threonine residue.	Threonine	313-322	myelin basic protein	Homo sapiens	81-101
6205122-1	1984	Polypeptides arising from neutral in vitro proteolysis of myelin basic protein (MBP) of human brain were evaluated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.	polyacrylamide	141-155	myelin basic protein	Homo sapiens	58-78
6205122-1	1984	Polypeptides arising from neutral in vitro proteolysis of myelin basic protein (MBP) of human brain were evaluated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.	polyacrylamide	141-155	myelin basic protein	Homo sapiens	80-83
6207945-0	1984	Interaction of myelin basic protein, melittin and bovine serum albumin with gangliosides, sulphatide and neutral glycosphingolipids in mixed monolayers.	Gangliosides	76-88	myelin basic protein	Homo sapiens	15-35
6204015-6	1984	The unusual triproline sequence of myelin basic protein (100-102) is enclosed in the 14-residue hairpin loop.	triproline	12-22	myelin basic protein	Homo sapiens	35-55
6204015-9	1984	Myelin basic protein is known to be phosphorylated in vivo on as many as five Ser/Thr residues.	Serine	78-81	myelin basic protein	Homo sapiens	0-20
6204015-9	1984	Myelin basic protein is known to be phosphorylated in vivo on as many as five Ser/Thr residues.	Threonine	82-85	myelin basic protein	Homo sapiens	0-20
6207945-0	1984	Interaction of myelin basic protein, melittin and bovine serum albumin with gangliosides, sulphatide and neutral glycosphingolipids in mixed monolayers.	Sulfoglycosphingolipids	90-100	myelin basic protein	Homo sapiens	15-35
6207945-0	1984	Interaction of myelin basic protein, melittin and bovine serum albumin with gangliosides, sulphatide and neutral glycosphingolipids in mixed monolayers.	Glycosphingolipids	113-131	myelin basic protein	Homo sapiens	15-35
6376683-4	1984	The soluble MBP immunoreactivities in placental homogenates and in maternal serum chromatograph identically on Sephadex G-50, and both these gestational MBP molecules migrate as though substantially larger than the MBP found in serum from patients with hypereosinophilic syndrome or purified from the eosinophil granule.	sephadex	111-124	myelin basic protein	Homo sapiens	12-15
6204974-0	1984	Surface accessibility of 13C-labeled lysine residues in membrane-bound myelin basic protein.	13c	25-28	myelin basic protein	Homo sapiens	71-91
6204974-0	1984	Surface accessibility of 13C-labeled lysine residues in membrane-bound myelin basic protein.	Lysine	37-43	myelin basic protein	Homo sapiens	71-91
6200137-0	1984	Calorimetric studies on the interaction of gangliosides with phospholipids and myelin basic protein.	Gangliosides	43-55	myelin basic protein	Homo sapiens	79-99
6205652-0	1984	The identification of threonine-95 as the major site of glycosylation in normal human myelin basic protein.	Threonine	22-31	myelin basic protein	Homo sapiens	86-106
6205652-1	1984	The enzymic transfer of N-acetylgalactosamine to myelin basic protein and that to peptides derived from basic protein were compared.	Acetylgalactosamine	24-45	myelin basic protein	Homo sapiens	49-69
6200137-4	1984	The influence of myelin basic protein on the thermotropic behaviour of GM1 was also studied.	G(M1) Ganglioside	71-74	myelin basic protein	Homo sapiens	17-37
6204218-0	1984	Phospholipid vesicle aggregation induced by human myelin basic protein.	Phospholipids	0-12	myelin basic protein	Homo sapiens	50-70
6199042-1	1984	Low-angle and wide-angle X-ray scattering data from phosphatidylglycerol complexed with myelin basic protein, poly(L-lysine) and calcium ions are analyzed.	Phosphatidylglycerols	52-72	myelin basic protein	Homo sapiens	88-108
6204218-1	1984	Human myelin basic protein isolated from the brains of individuals who died with multiple sclerosis was more potent in inducing the aggregation of egg phosphatidylcholine vesicles than was the basic protein isolated from the brains of normal individuals.	Phosphatidylcholines	151-170	myelin basic protein	Homo sapiens	6-26
6204218-2	1984	The portion of myelin basic protein which bound to egg phosphatidylcholine vesicles was separated from the free protein by sucrose density gradient centrifugation.	Sucrose	123-130	myelin basic protein	Homo sapiens	15-35
6644025-6	1983	MBP, ECP, and EDN eluted at different volumes from Sephadex G-50 columns as determined by RIA and SDS-PAGE.	sephadex	51-59	myelin basic protein	Homo sapiens	0-3
6209415-0	1984	Interaction of ganglioside GM1 and myelin basic protein studied by carbon-13 and proton nuclear magnetic resonance spectroscopy.	Carbon-13	67-76	myelin basic protein	Homo sapiens	35-55
6209415-1	1984	The interaction of the myelin basic protein (MBP) and the major endogenous ganglioside GM1 in myelin of the central nervous system has been investigated using both 500-MHz 1H and 67.89 MHz 13C NMR.	Gangliosides	75-86	myelin basic protein	Homo sapiens	45-48
6209415-1	1984	The interaction of the myelin basic protein (MBP) and the major endogenous ganglioside GM1 in myelin of the central nervous system has been investigated using both 500-MHz 1H and 67.89 MHz 13C NMR.	Hydrogen	172-174	myelin basic protein	Homo sapiens	23-43
6209415-1	1984	The interaction of the myelin basic protein (MBP) and the major endogenous ganglioside GM1 in myelin of the central nervous system has been investigated using both 500-MHz 1H and 67.89 MHz 13C NMR.	Hydrogen	172-174	myelin basic protein	Homo sapiens	45-48
6209415-1	1984	The interaction of the myelin basic protein (MBP) and the major endogenous ganglioside GM1 in myelin of the central nervous system has been investigated using both 500-MHz 1H and 67.89 MHz 13C NMR.	Carbon-13	189-192	myelin basic protein	Homo sapiens	23-43
6209415-1	1984	The interaction of the myelin basic protein (MBP) and the major endogenous ganglioside GM1 in myelin of the central nervous system has been investigated using both 500-MHz 1H and 67.89 MHz 13C NMR.	Carbon-13	189-192	myelin basic protein	Homo sapiens	45-48
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	G(M1) Ganglioside	20-23	myelin basic protein	Homo sapiens	13-16
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	G(M1) Ganglioside	20-23	myelin basic protein	Homo sapiens	90-93
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	G(M1) Ganglioside	20-23	myelin basic protein	Homo sapiens	90-93
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	Carbon-13	36-39	myelin basic protein	Homo sapiens	13-16
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	Carbon-13	36-39	myelin basic protein	Homo sapiens	90-93
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	Carbon-13	36-39	myelin basic protein	Homo sapiens	90-93
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	Histidine	74-77	myelin basic protein	Homo sapiens	13-16
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	Histidine	74-77	myelin basic protein	Homo sapiens	90-93
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	Histidine	74-77	myelin basic protein	Homo sapiens	90-93
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	G(M1) Ganglioside	99-102	myelin basic protein	Homo sapiens	13-16
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	G(M1) Ganglioside	99-102	myelin basic protein	Homo sapiens	90-93
6209415-2	1984	Titration of MBP by GM1 resulted in 13C NMR signal shifts for the I1e and His residues of MBP at a GM1/MBP mole ratio of one or less.	G(M1) Ganglioside	99-102	myelin basic protein	Homo sapiens	90-93
6209415-8	1984	However, as the GM1/MBP mole ratio was increased to eight or greater a major conformational change of MBP was detected.	G(M1) Ganglioside	16-19	myelin basic protein	Homo sapiens	102-105
6209415-9	1984	An upfield shift of the GM1 midchain methylene resonance was observed for the GM1/MBP complex.	G(M1) Ganglioside	24-27	myelin basic protein	Homo sapiens	82-85
6209415-9	1984	An upfield shift of the GM1 midchain methylene resonance was observed for the GM1/MBP complex.	G(M1) Ganglioside	78-81	myelin basic protein	Homo sapiens	82-85
6209415-10	1984	This observation provides strong evidence that the state of GM1 interacting with MBP is different from that of GM1 micelles.	G(M1) Ganglioside	60-63	myelin basic protein	Homo sapiens	81-84
6209415-11	1984	The number of saturable GM1 binding sites on MBP is estimated to be four.	G(M1) Ganglioside	24-27	myelin basic protein	Homo sapiens	45-48
6209415-13	1984	Interaction of MBP with the oligosaccharide derived from GM1 was found to be weaker than with GM1.	Oligosaccharides	28-43	myelin basic protein	Homo sapiens	15-18
6209415-13	1984	Interaction of MBP with the oligosaccharide derived from GM1 was found to be weaker than with GM1.	G(M1) Ganglioside	57-60	myelin basic protein	Homo sapiens	15-18
6209415-13	1984	Interaction of MBP with the oligosaccharide derived from GM1 was found to be weaker than with GM1.	G(M1) Ganglioside	94-97	myelin basic protein	Homo sapiens	15-18
6209415-14	1984	Based on our data, a model for the interaction can be proposed: the first GM1 molecule is bound to the protein molecule through its head group and hydrocarbon chains, followed by the formation of a GM1/MBP complex with a concomitant conformational change of MBP as more GM1 is added.	G(M1) Ganglioside	74-77	myelin basic protein	Homo sapiens	202-205
6209415-14	1984	Based on our data, a model for the interaction can be proposed: the first GM1 molecule is bound to the protein molecule through its head group and hydrocarbon chains, followed by the formation of a GM1/MBP complex with a concomitant conformational change of MBP as more GM1 is added.	G(M1) Ganglioside	74-77	myelin basic protein	Homo sapiens	258-261
6209415-14	1984	Based on our data, a model for the interaction can be proposed: the first GM1 molecule is bound to the protein molecule through its head group and hydrocarbon chains, followed by the formation of a GM1/MBP complex with a concomitant conformational change of MBP as more GM1 is added.	Hydrocarbons	147-158	myelin basic protein	Homo sapiens	202-205
6209415-14	1984	Based on our data, a model for the interaction can be proposed: the first GM1 molecule is bound to the protein molecule through its head group and hydrocarbon chains, followed by the formation of a GM1/MBP complex with a concomitant conformational change of MBP as more GM1 is added.	G(M1) Ganglioside	198-201	myelin basic protein	Homo sapiens	202-205
6209415-14	1984	Based on our data, a model for the interaction can be proposed: the first GM1 molecule is bound to the protein molecule through its head group and hydrocarbon chains, followed by the formation of a GM1/MBP complex with a concomitant conformational change of MBP as more GM1 is added.	G(M1) Ganglioside	198-201	myelin basic protein	Homo sapiens	258-261
6209415-14	1984	Based on our data, a model for the interaction can be proposed: the first GM1 molecule is bound to the protein molecule through its head group and hydrocarbon chains, followed by the formation of a GM1/MBP complex with a concomitant conformational change of MBP as more GM1 is added.	G(M1) Ganglioside	198-201	myelin basic protein	Homo sapiens	202-205
6209415-14	1984	Based on our data, a model for the interaction can be proposed: the first GM1 molecule is bound to the protein molecule through its head group and hydrocarbon chains, followed by the formation of a GM1/MBP complex with a concomitant conformational change of MBP as more GM1 is added.	G(M1) Ganglioside	198-201	myelin basic protein	Homo sapiens	258-261
6201246-0	1984	Comparison of metastable phase behavior of the complexes of dipalmitoyl phosphatidylglycerol with Mg+2 and myelin basic protein.	1,2-dipalmitoylphosphatidylglycerol	60-92	myelin basic protein	Homo sapiens	107-127
6201246-1	1984	Both divalent cations and myelin basic protein (BP) induce metastable phase behavior in phosphatidylglycerol (PG).	Phosphatidylglycerols	88-108	myelin basic protein	Homo sapiens	26-46
6201246-1	1984	Both divalent cations and myelin basic protein (BP) induce metastable phase behavior in phosphatidylglycerol (PG).	Phosphatidylglycerols	110-112	myelin basic protein	Homo sapiens	26-46
6363816-1	1984	We investigated the association between eosinophil degranulation, as evidenced by the deposition of granule major basic protein (MBP), and the killing of microfilariae of Onchocerca volvulus in vivo following treatment with diethylcarbamazine (DEC).	Diethylcarbamazine	224-242	myelin basic protein	Homo sapiens	129-132
6363816-2	1984	Utilizing an immunofluorescence procedure for the cellular and extracellular localization of eosinophil MBP in formalin-fixed, paraffin-embedded tissues, we studied skin biopsies from onchocerciasis patients before and during treatment with topically or orally administered DEC. Before DEC, there was little or no inflammatory response in either dermis or epidermis and microfilariae were essentially intact.	Formaldehyde	111-119	myelin basic protein	Homo sapiens	104-107
6363816-2	1984	Utilizing an immunofluorescence procedure for the cellular and extracellular localization of eosinophil MBP in formalin-fixed, paraffin-embedded tissues, we studied skin biopsies from onchocerciasis patients before and during treatment with topically or orally administered DEC. Before DEC, there was little or no inflammatory response in either dermis or epidermis and microfilariae were essentially intact.	Paraffin	127-135	myelin basic protein	Homo sapiens	104-107
6363816-4	1984	In contrast, during treatment with DEC, immunofluorescent staining for MBP revealed extensive eosinophil infiltrates in both dermis and epidermis with numerous intraepidermal eosinophil abscesses containing degenerating microfilariae.	Diethylcarbamazine	35-38	myelin basic protein	Homo sapiens	71-74
6363816-7	1984	The results show that immediately following administration of DEC, eosinophils localize and degranulate around microfilariae in the skin and release granule MBP onto or in close proximity to the parasite"s surface.	Diethylcarbamazine	62-65	myelin basic protein	Homo sapiens	157-160
6194825-2	1983	1.2-1.5 mol of N-acetylgalactosamine were transfered per mol of myelin basic protein.	Acetylgalactosamine	15-36	myelin basic protein	Homo sapiens	64-84
6644025-6	1983	MBP, ECP, and EDN eluted at different volumes from Sephadex G-50 columns as determined by RIA and SDS-PAGE.	Sodium Dodecyl Sulfate	98-101	myelin basic protein	Homo sapiens	0-3
6187818-1	1983	Complement-mediated lysis of reconstituted lipid-myelin basic protein (BP) vesicles and myelin vesicles due to antibody raised against BP and isolated myelin is measured by determination of the amount of a water-soluble spin label, tempocholine chloride, released from the vesicles.	Benzo(a)pyrene	71-73	myelin basic protein	Homo sapiens	49-69
6854212-2	1983	In this report, we demonstrate that MBP from human eosinophil granules initiates a nonlytic histamine release from human leukocytes.	Histamine	92-101	myelin basic protein	Homo sapiens	36-39
6189970-5	1983	In MS patients a positive correlation was seen between lymphocyte responses to myelin basic protein and to gangliosides.	Gangliosides	107-119	myelin basic protein	Homo sapiens	79-99
6197152-3	1983	Final identification of MBP from Raji eluates was done by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) followed by MBP radioimmunoassay (RIA) of gel eluates and by an immunoblot technique.	Sodium Dodecyl Sulfate	58-80	myelin basic protein	Homo sapiens	24-27
6197152-3	1983	Final identification of MBP from Raji eluates was done by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) followed by MBP radioimmunoassay (RIA) of gel eluates and by an immunoblot technique.	polyacrylamide	81-95	myelin basic protein	Homo sapiens	24-27
6197152-3	1983	Final identification of MBP from Raji eluates was done by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) followed by MBP radioimmunoassay (RIA) of gel eluates and by an immunoblot technique.	Sodium Dodecyl Sulfate	117-120	myelin basic protein	Homo sapiens	24-27
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Alanine	170-173	myelin basic protein	Homo sapiens	97-117
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Alanine	170-173	myelin basic protein	Homo sapiens	118-121
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Alanine	170-173	myelin basic protein	Homo sapiens	237-240
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Serine	174-177	myelin basic protein	Homo sapiens	97-117
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Serine	174-177	myelin basic protein	Homo sapiens	118-121
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Serine	174-177	myelin basic protein	Homo sapiens	237-240
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Aspartic Acid	178-181	myelin basic protein	Homo sapiens	97-117
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Aspartic Acid	178-181	myelin basic protein	Homo sapiens	118-121
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Aspartic Acid	178-181	myelin basic protein	Homo sapiens	237-240
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Tyrosine	182-185	myelin basic protein	Homo sapiens	97-117
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Tyrosine	182-185	myelin basic protein	Homo sapiens	118-121
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Tyrosine	182-185	myelin basic protein	Homo sapiens	237-240
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Lysine	186-189	myelin basic protein	Homo sapiens	97-117
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Lysine	186-189	myelin basic protein	Homo sapiens	118-121
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Lysine	186-189	myelin basic protein	Homo sapiens	237-240
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Serine	190-193	myelin basic protein	Homo sapiens	97-117
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Serine	190-193	myelin basic protein	Homo sapiens	118-121
6194176-1	1983	From an examination of electroimmunoblots and peptide maps, a mouse monoclonal antibody to human myelin basic protein MBP was shown to react with the amino acid sequence Ala-Ser-Asp-Tyr-Lys-Ser which is located in the C-terminal half of MBP.	Serine	190-193	myelin basic protein	Homo sapiens	237-240
6650126-1	1983	I has been reported that myelin basic protein (BP) reacts extremely sensitively to peroxide, which is formed when monocytes/macrophages are stimulated to produce a "respiratory burst" (RB).	Peroxides	83-91	myelin basic protein	Homo sapiens	25-45
6347236-4	1983	The pattern of MBP extracellular staining corresponded to the configuration of each flame figure (as verified by counterstain of the same section with haematoxylin and eosin).	Hematoxylin	151-163	myelin basic protein	Homo sapiens	15-18
6347236-4	1983	The pattern of MBP extracellular staining corresponded to the configuration of each flame figure (as verified by counterstain of the same section with haematoxylin and eosin).	Eosine Yellowish-(YS)	168-173	myelin basic protein	Homo sapiens	15-18
6189513-0	1983	Stopped-flow studies of myelin basic protein association with phospholipid vesicles and subsequent vesicle aggregation.	Phospholipids	62-74	myelin basic protein	Homo sapiens	24-44
6189513-1	1983	When mixed with vesicles containing acidic phospholipids, myelin basic protein causes vesicle aggregation.	Phospholipids	43-56	myelin basic protein	Homo sapiens	58-78
6185565-8	1983	Panitch and Ciccone (3) have reported induction of recurrent EAE in rats immunized with human MBP.	ciccone	12-19	myelin basic protein	Homo sapiens	94-97
6188001-0	1983	The structure of a serotonin and LSD binding site of myelin basic protein.	Serotonin	19-28	myelin basic protein	Homo sapiens	53-73
6188001-1	1983	Experiments have established the presence of a serotonin binding site in the tryptophan region of myelin basic protein.	Serotonin	47-56	myelin basic protein	Homo sapiens	98-118
6188001-1	1983	Experiments have established the presence of a serotonin binding site in the tryptophan region of myelin basic protein.	Tryptophan	77-87	myelin basic protein	Homo sapiens	98-118
6177329-1	1982	Mice bearing a methylcholanthrene-induced tumour were tested for their cell mediated reactivity to the experimental allergic encephalomyelitis (EAE) peptide of human myelin basic protein (MBP) in the leucocyte adherence inhibition (LAI) test.	Methylcholanthrene	15-33	myelin basic protein	Homo sapiens	166-186
6765519-9	1982	When switched from MBP to human insulin, there was a marked reduction in all parameters of binding, both qualitative and quantitative: SBP, -68%; SBH, -61%; SBB, -57%; bound insulin, -67% (all P less than 0.001) and decreases in high- and low-affinity binding capacities (P less than 0.02).	Sudan Black B	157-160	myelin basic protein	Homo sapiens	19-22
6878848-6	1983	During the course of their hospital stay the sputum MBP levels fell significantly following treatment with steroids and broncho-dilators.	Steroids	107-115	myelin basic protein	Homo sapiens	52-55
6878848-7	1983	The measurement of the MBP level would seem useful in those situations where the diagnosis of asthma is not evident from the history and may help in predicting the effectiveness of steroid treatment.	Steroids	181-188	myelin basic protein	Homo sapiens	23-26
6186278-1	1982	Myelin basic protein caused rapid aggregation of vesicles containing acidic phospholipids.	Phospholipids	76-89	myelin basic protein	Homo sapiens	0-20
6177329-1	1982	Mice bearing a methylcholanthrene-induced tumour were tested for their cell mediated reactivity to the experimental allergic encephalomyelitis (EAE) peptide of human myelin basic protein (MBP) in the leucocyte adherence inhibition (LAI) test.	Methylcholanthrene	15-33	myelin basic protein	Homo sapiens	188-191
6175158-2	1982	In patients with multiple sclerosis (MS) there is not only an antibody-dependent lymphocyte cytotoxicity (ADLC) against basic protein of myelin (MBP), as was demonstrated earlier, but also against encephalitogenic peptide, cerebrosides and gangliosides.	Cerebrosides	223-235	myelin basic protein	Homo sapiens	145-148
6175644-0	1982	Binding of myelin basic protein to phospholipid micelles.	Phospholipids	35-47	myelin basic protein	Homo sapiens	11-31
6175644-1	1982	Resonances of 1H NMR spectra (360 MHz) due to several individual substituents of myelin basic protein reconstituted into phospholipid micelles have been resolved and assigned.	Hydrogen	14-16	myelin basic protein	Homo sapiens	81-101
6175644-1	1982	Resonances of 1H NMR spectra (360 MHz) due to several individual substituents of myelin basic protein reconstituted into phospholipid micelles have been resolved and assigned.	Phospholipids	121-133	myelin basic protein	Homo sapiens	81-101
6175644-2	1982	With the aid of spin echo techniques to remove overlapping signals in the region of 2-3 ppm, singlet resonances due to the two myelin basic protein methionine S--CH3 groups (Met-20 and Met-167) and the Ala-1 N-acetyl methyl group were observed.	Methionine	148-158	myelin basic protein	Homo sapiens	127-147
6176267-0	1982	Effect of pH and fatty acid chain length on the interaction of myelin basic protein with phosphatidylglycerol.	Fatty Acids	17-27	myelin basic protein	Homo sapiens	63-83
6176267-0	1982	Effect of pH and fatty acid chain length on the interaction of myelin basic protein with phosphatidylglycerol.	Phosphatidylglycerols	89-109	myelin basic protein	Homo sapiens	63-83
19431499-0	1982	Interdigitation of Fatty Acid chains of dipalmitoylphosphatidylglycerol due to intercalation of myelin basic protein.	Fatty Acids	19-29	myelin basic protein	Homo sapiens	96-116
19431499-0	1982	Interdigitation of Fatty Acid chains of dipalmitoylphosphatidylglycerol due to intercalation of myelin basic protein.	1,2-dipalmitoylphosphatidylglycerol	40-71	myelin basic protein	Homo sapiens	96-116
6178922-0	1982	[Pathohistologic changes after induction cytostatic therapy with methotrexate (M), bleomycin (B) and cisplatin (P)--(MBP)].	Methotrexate	65-77	myelin basic protein	Homo sapiens	117-120
6178922-0	1982	[Pathohistologic changes after induction cytostatic therapy with methotrexate (M), bleomycin (B) and cisplatin (P)--(MBP)].	Cisplatin	101-110	myelin basic protein	Homo sapiens	117-120
6175158-2	1982	In patients with multiple sclerosis (MS) there is not only an antibody-dependent lymphocyte cytotoxicity (ADLC) against basic protein of myelin (MBP), as was demonstrated earlier, but also against encephalitogenic peptide, cerebrosides and gangliosides.	Gangliosides	240-252	myelin basic protein	Homo sapiens	145-148
6170387-0	1981	Myelin basic protein interacts with the myelin-specific ganglioside GM4.	Gangliosides	56-67	myelin basic protein	Homo sapiens	0-20
6171298-0	1981	Interaction of myelin basic protein with dipalmitoylphosphatidylglycerol: dependence on the lipid phase and investigation of a metastable state.	1,2-dipalmitoylphosphatidylglycerol	41-72	myelin basic protein	Homo sapiens	15-35
6180133-1	1982	The amino acid sequence around the sole methylarginine residue in chicken myelin basic protein was determined and was found to be similar to that previously reported for mammalian myelin basic protein.	Methylarginine	40-54	myelin basic protein	Homo sapiens	180-200
6170387-0	1981	Myelin basic protein interacts with the myelin-specific ganglioside GM4.	gm4	68-71	myelin basic protein	Homo sapiens	0-20
6170387-2	1981	We have found that myelin basic protein is capable of releasing large quantities of entrapped [14C]glucose from multilamellar liposomes containing GM4.	Carbon-14	95-98	myelin basic protein	Homo sapiens	19-39
6170387-2	1981	We have found that myelin basic protein is capable of releasing large quantities of entrapped [14C]glucose from multilamellar liposomes containing GM4.	Glucose	99-106	myelin basic protein	Homo sapiens	19-39
6170387-2	1981	We have found that myelin basic protein is capable of releasing large quantities of entrapped [14C]glucose from multilamellar liposomes containing GM4.	gm4	147-150	myelin basic protein	Homo sapiens	19-39
6165382-1	1981	The interaction of free and immobilized myelin basic protein (MBP) with sodium deoxycholate (DOC) and sodium dodecyl sulfate (NaDodSO4) was studied under a variety of conditions.	Deoxycholic Acid	72-91	myelin basic protein	Homo sapiens	40-60
6171986-2	1981	Purified basic protein of myelin (MBP) was adsorbed onto polystyrene beads, followed by incubation in dilutions of serum or cerebrospinal fluid (CSF).	Polystyrenes	57-68	myelin basic protein	Homo sapiens	34-37
6164508-1	1981	Hydrophobic compounds influenced the accuracy of the radioimmunoassay for myelin basic protein when lipids (stearic acid, phosphatidylcholine, cholesterol, cerebroside, sulfatide, or GM1 ganglioside) or proteolipids (white-matter proteolipid apoprotein, kidney proteolipid apoproteins, or heart proteolipid apoproteins) were added to a known amount of basic protein and the samples assayed.	stearic acid	108-120	myelin basic protein	Homo sapiens	74-94
6164508-1	1981	Hydrophobic compounds influenced the accuracy of the radioimmunoassay for myelin basic protein when lipids (stearic acid, phosphatidylcholine, cholesterol, cerebroside, sulfatide, or GM1 ganglioside) or proteolipids (white-matter proteolipid apoprotein, kidney proteolipid apoproteins, or heart proteolipid apoproteins) were added to a known amount of basic protein and the samples assayed.	Phosphatidylcholines	122-141	myelin basic protein	Homo sapiens	74-94
6164508-1	1981	Hydrophobic compounds influenced the accuracy of the radioimmunoassay for myelin basic protein when lipids (stearic acid, phosphatidylcholine, cholesterol, cerebroside, sulfatide, or GM1 ganglioside) or proteolipids (white-matter proteolipid apoprotein, kidney proteolipid apoproteins, or heart proteolipid apoproteins) were added to a known amount of basic protein and the samples assayed.	Cholesterol	143-154	myelin basic protein	Homo sapiens	74-94
6164508-1	1981	Hydrophobic compounds influenced the accuracy of the radioimmunoassay for myelin basic protein when lipids (stearic acid, phosphatidylcholine, cholesterol, cerebroside, sulfatide, or GM1 ganglioside) or proteolipids (white-matter proteolipid apoprotein, kidney proteolipid apoproteins, or heart proteolipid apoproteins) were added to a known amount of basic protein and the samples assayed.	Cerebrosides	156-167	myelin basic protein	Homo sapiens	74-94
6164508-1	1981	Hydrophobic compounds influenced the accuracy of the radioimmunoassay for myelin basic protein when lipids (stearic acid, phosphatidylcholine, cholesterol, cerebroside, sulfatide, or GM1 ganglioside) or proteolipids (white-matter proteolipid apoprotein, kidney proteolipid apoproteins, or heart proteolipid apoproteins) were added to a known amount of basic protein and the samples assayed.	Sulfoglycosphingolipids	169-178	myelin basic protein	Homo sapiens	74-94
6171190-3	1981	Peptide mapping and staining with amido black confirmed the identity of the 20,000 MW protein of mammalian NF fractions as MBP.	Amido Black	34-45	myelin basic protein	Homo sapiens	123-126
6168313-0	1981	Conformational properties of central nervous system myelin basic protein, beta-endorphin, and beta-lipotropin in water and in the presence of anionic lipids.	Water	113-118	myelin basic protein	Homo sapiens	52-72
6166320-1	1981	Phosphorescence from the lone tryptophan residue has been studied to monitor the interaction of myelin basic protein with phosphatidylserine vesicles.	Tryptophan	30-40	myelin basic protein	Homo sapiens	96-116
6165382-1	1981	The interaction of free and immobilized myelin basic protein (MBP) with sodium deoxycholate (DOC) and sodium dodecyl sulfate (NaDodSO4) was studied under a variety of conditions.	Deoxycholic Acid	72-91	myelin basic protein	Homo sapiens	62-65
6165382-1	1981	The interaction of free and immobilized myelin basic protein (MBP) with sodium deoxycholate (DOC) and sodium dodecyl sulfate (NaDodSO4) was studied under a variety of conditions.	Deoxycholic Acid	93-96	myelin basic protein	Homo sapiens	40-60
6165382-1	1981	The interaction of free and immobilized myelin basic protein (MBP) with sodium deoxycholate (DOC) and sodium dodecyl sulfate (NaDodSO4) was studied under a variety of conditions.	Deoxycholic Acid	93-96	myelin basic protein	Homo sapiens	62-65
6165382-1	1981	The interaction of free and immobilized myelin basic protein (MBP) with sodium deoxycholate (DOC) and sodium dodecyl sulfate (NaDodSO4) was studied under a variety of conditions.	Sodium Dodecyl Sulfate	102-124	myelin basic protein	Homo sapiens	40-60
6165382-1	1981	The interaction of free and immobilized myelin basic protein (MBP) with sodium deoxycholate (DOC) and sodium dodecyl sulfate (NaDodSO4) was studied under a variety of conditions.	Sodium Dodecyl Sulfate	102-124	myelin basic protein	Homo sapiens	62-65
6165382-1	1981	The interaction of free and immobilized myelin basic protein (MBP) with sodium deoxycholate (DOC) and sodium dodecyl sulfate (NaDodSO4) was studied under a variety of conditions.	nadodso4	126-134	myelin basic protein	Homo sapiens	40-60
6165382-6	1981	Complete equilibrium binding isotherms of both detergents to the protein were obtained by using MBP immobilized on agarose.	Sepharose	115-122	myelin basic protein	Homo sapiens	96-99
6165382-10	1981	Affinity chromatography studies indicated that, in the presence of NaDodSO4 (but not in its absence), [125I]MBP interacted with agarose-immobilized histone, lysozyme, and MBP but did not interact with ovalbumin-agarose.	nadodso4	67-75	myelin basic protein	Homo sapiens	108-111
6165382-10	1981	Affinity chromatography studies indicated that, in the presence of NaDodSO4 (but not in its absence), [125I]MBP interacted with agarose-immobilized histone, lysozyme, and MBP but did not interact with ovalbumin-agarose.	nadodso4	67-75	myelin basic protein	Homo sapiens	171-174
6165382-10	1981	Affinity chromatography studies indicated that, in the presence of NaDodSO4 (but not in its absence), [125I]MBP interacted with agarose-immobilized histone, lysozyme, and MBP but did not interact with ovalbumin-agarose.	Sepharose	128-135	myelin basic protein	Homo sapiens	108-111
6165382-10	1981	Affinity chromatography studies indicated that, in the presence of NaDodSO4 (but not in its absence), [125I]MBP interacted with agarose-immobilized histone, lysozyme, and MBP but did not interact with ovalbumin-agarose.	Sepharose	211-218	myelin basic protein	Homo sapiens	108-111
6173394-1	1981	A solid phase radioimmunoassay (RIA) for the detection of antibodies to myelin basic protein (MBP) in sera has been developed employing MBP-coated flexible polyvinylchloride microtiter trays and [125I]protein-A as the radiolabel.	Polyvinyl Chloride	156-173	myelin basic protein	Homo sapiens	94-97
6173394-1	1981	A solid phase radioimmunoassay (RIA) for the detection of antibodies to myelin basic protein (MBP) in sera has been developed employing MBP-coated flexible polyvinylchloride microtiter trays and [125I]protein-A as the radiolabel.	Polyvinyl Chloride	156-173	myelin basic protein	Homo sapiens	136-139
6171252-1	1981	The penetration of melittin and myelin basic protein into glycosphingolipid monolayers depends on the lipid polar head group, the protein concentration available and the initial surface pressure.	Glycosphingolipids	58-75	myelin basic protein	Homo sapiens	32-52
6164021-2	1981	Cycloleucine, an inhibitor of the formation of S-adenosylmethionine, decreased the incorporation of methyl groups into methylarginine in myelin basic protein in vivo.	Cycloleucine	0-12	myelin basic protein	Homo sapiens	137-157
6164021-2	1981	Cycloleucine, an inhibitor of the formation of S-adenosylmethionine, decreased the incorporation of methyl groups into methylarginine in myelin basic protein in vivo.	S-Adenosylmethionine	47-67	myelin basic protein	Homo sapiens	137-157
7204553-6	1981	Analyses of serum by Sephadex G-200 and by electrofocusing suggest that MBP is not simply polymerized, but rather is bound to a larger carrier molecule.	sephadex	21-35	myelin basic protein	Homo sapiens	72-75
7204553-7	1981	Monomeric MBP can be isolated from serum by reduction of serum with dithiothreitol, alkylation with iodoacetamide, and acidification to pH 2 followed by fractionation on Sephadex G-50 at pH 2.	Dithiothreitol	68-82	myelin basic protein	Homo sapiens	10-13
7204553-7	1981	Monomeric MBP can be isolated from serum by reduction of serum with dithiothreitol, alkylation with iodoacetamide, and acidification to pH 2 followed by fractionation on Sephadex G-50 at pH 2.	Iodoacetamide	100-113	myelin basic protein	Homo sapiens	10-13
7204553-7	1981	Monomeric MBP can be isolated from serum by reduction of serum with dithiothreitol, alkylation with iodoacetamide, and acidification to pH 2 followed by fractionation on Sephadex G-50 at pH 2.	sephadex	170-183	myelin basic protein	Homo sapiens	10-13
6164021-2	1981	Cycloleucine, an inhibitor of the formation of S-adenosylmethionine, decreased the incorporation of methyl groups into methylarginine in myelin basic protein in vivo.	Methylarginine	119-133	myelin basic protein	Homo sapiens	137-157
6164021-3	1981	The need for methylcobalamin for the conversion of homocysteine to methionine and the requirement that myelin basic protein may be methylated, offer a rational explanation for the myelin lesions observed in cases of vitamin B12 deficiency where there is increasing evidence that methyl-, rather than adenosylcobalamin is required to prevent dysmyelination.	Vitamin B 12	216-227	myelin basic protein	Homo sapiens	103-123
6161042-0	1980	Phospholipase C (Bacillus cereus) digestion of phospholipids in myelin isolated from central nervous tissue: removal of myelin basic protein increases exposure of lipids to the enzyme.	Phospholipids	47-60	myelin basic protein	Homo sapiens	120-140
6938923-0	1981	[Acceptance program for alloys to metal-bounding porcelain (MBP alloys), type 1 with hight content of metals (78 weight percent)].	Metals	34-39	myelin basic protein	Homo sapiens	60-63
6160344-9	1981	The mean blood pressure change (delta MBP%) was significantly correlated with the plasma level of prazosin in the renal failure group (n = 97, r = 0.489, p &lt; 0.001) but not in patients with normal renal function (n = 74, r = 0.297, ns).	Prazosin	98-106	myelin basic protein	Homo sapiens	38-42
7438542-5	1980	This smaller protein was thought to be the bovine equivalent of guinea-pig and human major basic protein (MBP), although it possessed an unusually high concentration of cysteine.	Cysteine	169-177	myelin basic protein	Homo sapiens	85-104
7000633-2	1980	A protein referred to as Mallory body protein (MBP), was isolated from MB by reduction and alkylation which gave one band an SDS-polyacrylamide electrophoresis.	Sodium Dodecyl Sulfate	125-128	myelin basic protein	Homo sapiens	25-45
7000633-2	1980	A protein referred to as Mallory body protein (MBP), was isolated from MB by reduction and alkylation which gave one band an SDS-polyacrylamide electrophoresis.	Sodium Dodecyl Sulfate	125-128	myelin basic protein	Homo sapiens	47-50
7000633-2	1980	A protein referred to as Mallory body protein (MBP), was isolated from MB by reduction and alkylation which gave one band an SDS-polyacrylamide electrophoresis.	polyacrylamide	129-143	myelin basic protein	Homo sapiens	25-45
7000633-2	1980	A protein referred to as Mallory body protein (MBP), was isolated from MB by reduction and alkylation which gave one band an SDS-polyacrylamide electrophoresis.	polyacrylamide	129-143	myelin basic protein	Homo sapiens	47-50
6155938-0	1980	Direct observation by carbon-13 nuclear magnetic resonance of membrane-bound human myelin basic protein.	Carbon-13	22-31	myelin basic protein	Homo sapiens	83-103
7438542-5	1980	This smaller protein was thought to be the bovine equivalent of guinea-pig and human major basic protein (MBP), although it possessed an unusually high concentration of cysteine.	Cysteine	169-177	myelin basic protein	Homo sapiens	106-109
75728-0	1978	Interaction of the myelin basic protein with the anionic detergent sodium dodecyl sulphate.	Sodium Dodecyl Sulfate	67-90	myelin basic protein	Homo sapiens	19-39
6102867-2	1980	Polysialogangliosides, sulphatides, glycerylmonooleate, unsaturated fatty acids, myelin basic protein and sucrose inhibit the Na+-coupled uptake and induce a Ca2+-dependent release of dopamine from nerve endings.	Dopamine	184-192	myelin basic protein	Homo sapiens	81-101
6102867-4	1980	Mixtures of polysialogangliosides or sulphatides with myelin basic protein or albumin inhibit, to different degrees, the effects of the individual components.	trisialoganglioside GT1	12-33	myelin basic protein	Homo sapiens	54-74
6102867-4	1980	Mixtures of polysialogangliosides or sulphatides with myelin basic protein or albumin inhibit, to different degrees, the effects of the individual components.	Sulfoglycosphingolipids	37-48	myelin basic protein	Homo sapiens	54-74
6161297-2	1980	In the presence of vaccinia virus cores maximally 1.5 mol and in the presence of intact virus 0.7 mol phosphate residues were incorporated into 1 mol of myelin basic protein in the myelin membrane.	Phosphates	102-111	myelin basic protein	Homo sapiens	153-173
88232-1	1979	Equilibrium measurements of the binding of central nervous system myelin basic protein to sodium dodecyl sulphate, sodium deoxycholate and lysophosphatidylcholine have been obtained by gel permeation chromatography and dialysis.	Sodium Dodecyl Sulfate	90-113	myelin basic protein	Homo sapiens	66-86
88232-1	1979	Equilibrium measurements of the binding of central nervous system myelin basic protein to sodium dodecyl sulphate, sodium deoxycholate and lysophosphatidylcholine have been obtained by gel permeation chromatography and dialysis.	Deoxycholic Acid	115-134	myelin basic protein	Homo sapiens	66-86
88232-1	1979	Equilibrium measurements of the binding of central nervous system myelin basic protein to sodium dodecyl sulphate, sodium deoxycholate and lysophosphatidylcholine have been obtained by gel permeation chromatography and dialysis.	Lysophosphatidylcholines	139-162	myelin basic protein	Homo sapiens	66-86
711741-7	1978	In the absence of cross-linking reagent, it was shown by radioimmunoassay that small amounts of myelin basic protein dimer and the heterodimer were normally present in sodium dodecyl sulfate-polyacrylamide gels.	Sodium Dodecyl Sulfate	168-190	myelin basic protein	Homo sapiens	96-116
711741-7	1978	In the absence of cross-linking reagent, it was shown by radioimmunoassay that small amounts of myelin basic protein dimer and the heterodimer were normally present in sodium dodecyl sulfate-polyacrylamide gels.	polyacrylamide	191-205	myelin basic protein	Homo sapiens	96-116
77196-0	1978	Silica gel radioimmunoassay for myelin basic protein.	Silicon Dioxide	0-6	myelin basic protein	Homo sapiens	32-52
6160001-1	1980	Bovine myelin basic protein was found to agglutinate polystyrene particles coated with human polyclonal IgG, monoclonal IgG1, or IgG Fc fragments, but not those coated with IgG F(ab")2 fragments, IgA, or IgM.	Polystyrenes	53-64	myelin basic protein	Homo sapiens	7-27
6160001-5	1980	The interaction between myelin basic protein and aggregated IgG was confirmed by gel exclusion experiments on Sephadex G-200.	sephadex	110-124	myelin basic protein	Homo sapiens	24-44
6157030-0	1980	Specificity of brain cathepsin D: cleavage of model peptides containing the susceptible Phe-Phe regions of myelin basic protein.	Phenylalanine	88-91	myelin basic protein	Homo sapiens	107-127
6157030-0	1980	Specificity of brain cathepsin D: cleavage of model peptides containing the susceptible Phe-Phe regions of myelin basic protein.	Phenylalanine	92-95	myelin basic protein	Homo sapiens	107-127
6157030-1	1980	Brain cathepsin D, purified by affinity chromatography on Sepharose pepstatin columns, was incubated with synthetic peptides corresponding to the susceptible regions of the myelin basic protein encompassing the two Phe-Phe bonds.	Peptides	116-124	myelin basic protein	Homo sapiens	173-193
6157030-1	1980	Brain cathepsin D, purified by affinity chromatography on Sepharose pepstatin columns, was incubated with synthetic peptides corresponding to the susceptible regions of the myelin basic protein encompassing the two Phe-Phe bonds.	Phenylalanine	215-218	myelin basic protein	Homo sapiens	173-193
6157030-1	1980	Brain cathepsin D, purified by affinity chromatography on Sepharose pepstatin columns, was incubated with synthetic peptides corresponding to the susceptible regions of the myelin basic protein encompassing the two Phe-Phe bonds.	Phenylalanine	219-222	myelin basic protein	Homo sapiens	173-193
6160602-1	1980	Lymphocytes from seven patients with malignancies, from seven patients with non-malignancies, and from five healthy persons were incubated with 125I-labeled MBP.	Iodine-125	144-148	myelin basic protein	Homo sapiens	157-160
92876-2	1979	125I-labelled human myelin basic protein was rapidly degraded by normal guinea pig serum to low molecular weight products as shown by polyacrylamide gel electrophoresis.	polyacrylamide	134-148	myelin basic protein	Homo sapiens	20-40
75728-1	1978	The interaction of the myelin basic protein and two peptides derived from it with the anionic detergent SDS (sodium dodecyl sulphate) was studied.	Sodium Dodecyl Sulfate	104-107	myelin basic protein	Homo sapiens	23-43
75728-1	1978	The interaction of the myelin basic protein and two peptides derived from it with the anionic detergent SDS (sodium dodecyl sulphate) was studied.	Sodium Dodecyl Sulfate	109-132	myelin basic protein	Homo sapiens	23-43
20951-1	1977	Myelin basic protein associates with bilayer vesicles of pure egg phosphatidylcholine, L-alpha-dimyristoyl phosphatidylcholine and DL-alpha-dipalmitoyl phosphatidylcholine.	Phosphatidylcholines	66-85	myelin basic protein	Homo sapiens	0-20
751346-3	1978	The deparaffinized sections are again treated with formalin in order to make the "unmasked" by the delipidization basic groups of MBP reactive to ammoniacal silver.	Formaldehyde	51-59	myelin basic protein	Homo sapiens	130-133
751346-5	1978	Deparaffinized sections subjected to an extraction of MBP with hydrochloric acid exhibit a negative reaction at the level of the myelin sheaths the same reaction being preserved at the level of the nuclear histones.	Hydrochloric Acid	63-80	myelin basic protein	Homo sapiens	54-57
80938-1	1978	High resolution 13C and 1H NMR spectra of myelin basic protein over a range of pH and concentrations indicate that intramolecular folding of the polypeptide chain occurs in aqueous solution in the region of residues 85 to 116.	13c	16-19	myelin basic protein	Homo sapiens	42-62
80938-1	1978	High resolution 13C and 1H NMR spectra of myelin basic protein over a range of pH and concentrations indicate that intramolecular folding of the polypeptide chain occurs in aqueous solution in the region of residues 85 to 116.	Hydrogen	24-26	myelin basic protein	Homo sapiens	42-62
80939-1	1978	Central nervous system myelin basic protein binds to the zwitterionic lipid, egg diacylphosphatidylcholine, over a wide range of pH and ionic strength.	diacylphosphatidylcholine	81-106	myelin basic protein	Homo sapiens	23-43
72562-0	1977	Phase separation of acidic and neutral phospholipids induced by human myelin basic protein.	Phospholipids	39-52	myelin basic protein	Homo sapiens	70-90
20951-1	1977	Myelin basic protein associates with bilayer vesicles of pure egg phosphatidylcholine, L-alpha-dimyristoyl phosphatidylcholine and DL-alpha-dipalmitoyl phosphatidylcholine.	Dimyristoylphosphatidylcholine	87-126	myelin basic protein	Homo sapiens	0-20
20951-1	1977	Myelin basic protein associates with bilayer vesicles of pure egg phosphatidylcholine, L-alpha-dimyristoyl phosphatidylcholine and DL-alpha-dipalmitoyl phosphatidylcholine.	dl-alpha-dipalmitoyl phosphatidylcholine	131-171	myelin basic protein	Homo sapiens	0-20
60466-0	1976	Mechanism of interaction of myelin basic protein and S-100 protein: metal binding and fluorescence studies.	Metals	68-73	myelin basic protein	Homo sapiens	28-48
838827-3	1977	The total analysis time was 9.5 h. In this procedure, particularly glucosamine, mannosamine and galactosamine were separated completely from normal "protein" amino acids, and NG-monomethylarginine, NG, NG-dimethylarginine and NG,NG-dimethylarginine, which were present in the myelin basic protein of several species and excreted in human urine, were separated from other basic amino acids.	Glucosamine	67-78	myelin basic protein	Homo sapiens	276-296
838827-3	1977	The total analysis time was 9.5 h. In this procedure, particularly glucosamine, mannosamine and galactosamine were separated completely from normal "protein" amino acids, and NG-monomethylarginine, NG, NG-dimethylarginine and NG,NG-dimethylarginine, which were present in the myelin basic protein of several species and excreted in human urine, were separated from other basic amino acids.	Galactosamine	96-109	myelin basic protein	Homo sapiens	276-296
71150-0	1977	Glucose release from liposomes containing gangliosides or other membrane lipids induced by biogenic amines and myelin basic protein.	Glucose	0-7	myelin basic protein	Homo sapiens	111-131
71150-0	1977	Glucose release from liposomes containing gangliosides or other membrane lipids induced by biogenic amines and myelin basic protein.	Gangliosides	42-54	myelin basic protein	Homo sapiens	111-131
61030-0	1976	Phosphorylation on basic amino acids in myelin basic protein.	Amino Acids, Basic	19-36	myelin basic protein	Homo sapiens	40-60
942977-1	1976	Guinea pig eosinophil granules contain a protein, the major basic protein (MBP), which accounts for more than half of the total granule protein, has a high content of arginine, and displays a remarkable tendency to form disulfide-linked aggregates.	Arginine	167-175	myelin basic protein	Homo sapiens	54-73
942977-1	1976	Guinea pig eosinophil granules contain a protein, the major basic protein (MBP), which accounts for more than half of the total granule protein, has a high content of arginine, and displays a remarkable tendency to form disulfide-linked aggregates.	Arginine	167-175	myelin basic protein	Homo sapiens	75-78
942977-1	1976	Guinea pig eosinophil granules contain a protein, the major basic protein (MBP), which accounts for more than half of the total granule protein, has a high content of arginine, and displays a remarkable tendency to form disulfide-linked aggregates.	Disulfides	220-229	myelin basic protein	Homo sapiens	54-73
942977-1	1976	Guinea pig eosinophil granules contain a protein, the major basic protein (MBP), which accounts for more than half of the total granule protein, has a high content of arginine, and displays a remarkable tendency to form disulfide-linked aggregates.	Disulfides	220-229	myelin basic protein	Homo sapiens	75-78
942977-6	1976	The human MBP had a molecular weight of 9,200, contained less than 1% carbohydrate, was rich in arginine, and readily formed disulfide-bonded aggregates.	Carbohydrates	70-82	myelin basic protein	Homo sapiens	10-13
942977-6	1976	The human MBP had a molecular weight of 9,200, contained less than 1% carbohydrate, was rich in arginine, and readily formed disulfide-bonded aggregates.	Arginine	96-104	myelin basic protein	Homo sapiens	10-13
942977-6	1976	The human MBP had a molecular weight of 9,200, contained less than 1% carbohydrate, was rich in arginine, and readily formed disulfide-bonded aggregates.	Disulfides	125-134	myelin basic protein	Homo sapiens	10-13
942977-11	1976	Human MBP and CLC protein differed in their molecular weights, carbohydrate compositions, and amino acid analyses.	Carbohydrates	63-75	myelin basic protein	Homo sapiens	6-9
942977-12	1976	Mixtures of the MBP and the CLC protein yielded two bands in polyacrylamide gel electrophoresis.	polyacrylamide	61-75	myelin basic protein	Homo sapiens	16-19
49400-0	1975	The presence of cysteine in frog myelin basic protein.	Cysteine	16-24	myelin basic protein	Homo sapiens	33-53
965966-0	1976	Microheterogeneity and phosphoamino acids in the carboxy-terminal half of myelin basic protein.	Phosphoamino Acids	23-41	myelin basic protein	Homo sapiens	74-94
60250-1	1976	Aerobic ascorbic acid solutions are capable of extensively cleaving the peptide chain of the myelin basic protein.	Ascorbic Acid	8-21	myelin basic protein	Homo sapiens	93-113
4459249-0	1974	Radioimmunoassay of myelin basic protein in sodium sulfate.	sodium sulfate	44-58	myelin basic protein	Homo sapiens	20-40
48264-1	1975	Guinea pigs injected with Freund"s incomplete adjuvant emulsified with guinea pig spinal cord, purified guinea pig myelin basic protein, or human myelin basic protein showed dermal reactivity to both of the basic proteins as well as to mycobacteria antigens.	freund"s incomplete adjuvant	26-54	myelin basic protein	Homo sapiens	146-166
4139129-0	1974	Adjuvant activity for alkylamines of immune responses to ovalbumin, myelin basic protein and a tumor.	alkylamines	22-33	myelin basic protein	Homo sapiens	68-88
4834691-0	1974	Bilirubin binding to myelin basic protein, histones and its inhibition in vitro of cerebellar protein synthesis.	Bilirubin	0-9	myelin basic protein	Homo sapiens	21-41
34010609-11	2021	Moreover, recent studies elucidated bioactive hyaluronan fragments interact with TLR4, initiating signaling cascades to mediate myelin basic protein (MBP) transcription.	Hyaluronic Acid	46-56	myelin basic protein	Homo sapiens	128-148
4738150-0	1973	The specific interaction of myelin basic protein with lipids at the air-water interface.	Water	72-77	myelin basic protein	Homo sapiens	28-48
4833512-0	1974	Phosphorylation of selected serine and threonine residues in myelin basic protein by endogenous and exogenous protein kinases.	Serine	28-34	myelin basic protein	Homo sapiens	61-81
4833512-0	1974	Phosphorylation of selected serine and threonine residues in myelin basic protein by endogenous and exogenous protein kinases.	Threonine	39-48	myelin basic protein	Homo sapiens	61-81
4983347-2	1970	Coprecipitation and radioautography of 125I-labeled antigen-antibody complexes for detection of antibodies to myelin basic protein.	Iodine-125	39-43	myelin basic protein	Homo sapiens	110-130
33998060-0	2021	Conformation of Myelin Basic Protein Bound to Phosphatidylinositol Membrane Characterized by Vacuum-Ultraviolet Circular-Dichroism Spectroscopy and Molecular-Dynamics Simulations.	Phosphatidylinositols	46-66	myelin basic protein	Homo sapiens	16-36
33998060-2	2021	This study characterized the conformation of MBP in the membrane by measuring the vacuum-ultraviolet circular-dichroism (VUVCD) spectra of MBP in the bilayer liposome comprising the following essential lipid constituents of the myelin sheath: phosphatidylinositol (PI), phosphatidylinositol-4-bisphosphate (PIP), and phosphatidylinositol-4,5-bisphosphate (PIP2).	Phosphatidylinositols	243-263	myelin basic protein	Homo sapiens	45-48
33998060-2	2021	This study characterized the conformation of MBP in the membrane by measuring the vacuum-ultraviolet circular-dichroism (VUVCD) spectra of MBP in the bilayer liposome comprising the following essential lipid constituents of the myelin sheath: phosphatidylinositol (PI), phosphatidylinositol-4-bisphosphate (PIP), and phosphatidylinositol-4,5-bisphosphate (PIP2).	phosphatidylinositol-4-bisphosphate	270-305	myelin basic protein	Homo sapiens	45-48
33998060-2	2021	This study characterized the conformation of MBP in the membrane by measuring the vacuum-ultraviolet circular-dichroism (VUVCD) spectra of MBP in the bilayer liposome comprising the following essential lipid constituents of the myelin sheath: phosphatidylinositol (PI), phosphatidylinositol-4-bisphosphate (PIP), and phosphatidylinositol-4,5-bisphosphate (PIP2).	pip	307-310	myelin basic protein	Homo sapiens	45-48
33998060-2	2021	This study characterized the conformation of MBP in the membrane by measuring the vacuum-ultraviolet circular-dichroism (VUVCD) spectra of MBP in the bilayer liposome comprising the following essential lipid constituents of the myelin sheath: phosphatidylinositol (PI), phosphatidylinositol-4-bisphosphate (PIP), and phosphatidylinositol-4,5-bisphosphate (PIP2).	Phosphatidylinositol 4,5-Diphosphate	317-354	myelin basic protein	Homo sapiens	45-48
33998060-2	2021	This study characterized the conformation of MBP in the membrane by measuring the vacuum-ultraviolet circular-dichroism (VUVCD) spectra of MBP in the bilayer liposome comprising the following essential lipid constituents of the myelin sheath: phosphatidylinositol (PI), phosphatidylinositol-4-bisphosphate (PIP), and phosphatidylinositol-4,5-bisphosphate (PIP2).	Phosphatidylinositol 4,5-Diphosphate	356-360	myelin basic protein	Homo sapiens	45-48
33998060-3	2021	The spectra of MBP exhibited the characteristic peaks of the helix structure in the presence of PI liposome, and the intensity increased markedly in the presence of PIP and PIP2 liposomes to show an isodichroic point.	pip	165-168	myelin basic protein	Homo sapiens	15-18
33998060-3	2021	The spectra of MBP exhibited the characteristic peaks of the helix structure in the presence of PI liposome, and the intensity increased markedly in the presence of PIP and PIP2 liposomes to show an isodichroic point.	Phosphatidylinositol 4,5-Diphosphate	173-177	myelin basic protein	Homo sapiens	15-18
34010609-11	2021	Moreover, recent studies elucidated bioactive hyaluronan fragments interact with TLR4, initiating signaling cascades to mediate myelin basic protein (MBP) transcription.	Hyaluronic Acid	46-56	myelin basic protein	Homo sapiens	150-153
33851853-2	2021	We present a novel equilibrium headspace gas chromatographic technique to examine the thermodynamics of noncovalent interactions between common perfume components: Lilial, Hedione, Hexylcinnamic aldehyde, and Versalide with MBP monomers and its hexameric MBP-pseudophase.	versalide	209-218	myelin basic protein	Homo sapiens	224-227
33319405-5	2021	Gd(III)-Gd(III) distances measured by double electron-electron resonance (DEER) experiments of maltose binding protein (MBP) containing two selenocysteine residues tagged with 4Cl-MDPA-Gd(III) were indistinguishable from Gd(III)-Gd(III) distances measured of MBP containing cysteine reacted with 4Br-MDPA tags.	Selenocysteine	140-154	myelin basic protein	Homo sapiens	95-118
33964746-9	2021	For instance, the model satisfactorily accounts for the yields of dibromophenols from oxidation of a 2-bromophenol (2-MBP) molecule, in reference to analogous experimental measurements.	dibromophenols	66-80	myelin basic protein	Homo sapiens	118-121
33964746-9	2021	For instance, the model satisfactorily accounts for the yields of dibromophenols from oxidation of a 2-bromophenol (2-MBP) molecule, in reference to analogous experimental measurements.	2-bromophenol	101-114	myelin basic protein	Homo sapiens	118-121
33964746-10	2021	From an environmental perspective, the model reflects the accumulation of appreciable loads of 2-bromophenoxy radicals at intermediate temperatures (i.e., a bromine-containing environmental persistent free radical, EPFR) from combustion of MBZ and 2-MBP molecules.	2-bromophenoxy radicals	95-118	myelin basic protein	Homo sapiens	250-253
33964746-10	2021	From an environmental perspective, the model reflects the accumulation of appreciable loads of 2-bromophenoxy radicals at intermediate temperatures (i.e., a bromine-containing environmental persistent free radical, EPFR) from combustion of MBZ and 2-MBP molecules.	Bromine	157-164	myelin basic protein	Homo sapiens	250-253
33319405-5	2021	Gd(III)-Gd(III) distances measured by double electron-electron resonance (DEER) experiments of maltose binding protein (MBP) containing two selenocysteine residues tagged with 4Cl-MDPA-Gd(III) were indistinguishable from Gd(III)-Gd(III) distances measured of MBP containing cysteine reacted with 4Br-MDPA tags.	Selenocysteine	140-154	myelin basic protein	Homo sapiens	120-123
33319405-5	2021	Gd(III)-Gd(III) distances measured by double electron-electron resonance (DEER) experiments of maltose binding protein (MBP) containing two selenocysteine residues tagged with 4Cl-MDPA-Gd(III) were indistinguishable from Gd(III)-Gd(III) distances measured of MBP containing cysteine reacted with 4Br-MDPA tags.	4-chlorocatechol	176-179	myelin basic protein	Homo sapiens	95-118
33319405-5	2021	Gd(III)-Gd(III) distances measured by double electron-electron resonance (DEER) experiments of maltose binding protein (MBP) containing two selenocysteine residues tagged with 4Cl-MDPA-Gd(III) were indistinguishable from Gd(III)-Gd(III) distances measured of MBP containing cysteine reacted with 4Br-MDPA tags.	4-chlorocatechol	176-179	myelin basic protein	Homo sapiens	120-123
33319405-5	2021	Gd(III)-Gd(III) distances measured by double electron-electron resonance (DEER) experiments of maltose binding protein (MBP) containing two selenocysteine residues tagged with 4Cl-MDPA-Gd(III) were indistinguishable from Gd(III)-Gd(III) distances measured of MBP containing cysteine reacted with 4Br-MDPA tags.	3-(Dimethylphosphono)-N-methylolpropionamide	180-184	myelin basic protein	Homo sapiens	95-118
33319405-5	2021	Gd(III)-Gd(III) distances measured by double electron-electron resonance (DEER) experiments of maltose binding protein (MBP) containing two selenocysteine residues tagged with 4Cl-MDPA-Gd(III) were indistinguishable from Gd(III)-Gd(III) distances measured of MBP containing cysteine reacted with 4Br-MDPA tags.	3-(Dimethylphosphono)-N-methylolpropionamide	180-184	myelin basic protein	Homo sapiens	120-123
33319405-5	2021	Gd(III)-Gd(III) distances measured by double electron-electron resonance (DEER) experiments of maltose binding protein (MBP) containing two selenocysteine residues tagged with 4Cl-MDPA-Gd(III) were indistinguishable from Gd(III)-Gd(III) distances measured of MBP containing cysteine reacted with 4Br-MDPA tags.	Cysteine	146-154	myelin basic protein	Homo sapiens	95-118
33319405-5	2021	Gd(III)-Gd(III) distances measured by double electron-electron resonance (DEER) experiments of maltose binding protein (MBP) containing two selenocysteine residues tagged with 4Cl-MDPA-Gd(III) were indistinguishable from Gd(III)-Gd(III) distances measured of MBP containing cysteine reacted with 4Br-MDPA tags.	Cysteine	146-154	myelin basic protein	Homo sapiens	120-123
33319405-5	2021	Gd(III)-Gd(III) distances measured by double electron-electron resonance (DEER) experiments of maltose binding protein (MBP) containing two selenocysteine residues tagged with 4Cl-MDPA-Gd(III) were indistinguishable from Gd(III)-Gd(III) distances measured of MBP containing cysteine reacted with 4Br-MDPA tags.	4br-mdpa	296-304	myelin basic protein	Homo sapiens	120-123
33008588-8	2020	First, we demonstrated our strategy using maltose-binding protein-fused green fluorescent protein (MBP-GFP) to model an acidic protein.	Maltose	42-49	myelin basic protein	Homo sapiens	99-102
33750840-6	2021	Zn2+ specifically induced oligomerization of both MBP-CRISP1 and MBP-CRISP1DeltaC in vitro.	Zinc	0-4	myelin basic protein	Homo sapiens	50-53
33750840-6	2021	Zn2+ specifically induced oligomerization of both MBP-CRISP1 and MBP-CRISP1DeltaC in vitro.	Zinc	0-4	myelin basic protein	Homo sapiens	65-68
33750840-8	2021	Furthermore, MBP-CRISP1 and MBP-CRISP1DeltaC oligomers dissociated into monomers upon Zn2+ removal by EDTA.	Zinc	86-90	myelin basic protein	Homo sapiens	13-16
33750840-8	2021	Furthermore, MBP-CRISP1 and MBP-CRISP1DeltaC oligomers dissociated into monomers upon Zn2+ removal by EDTA.	Edetic Acid	102-106	myelin basic protein	Homo sapiens	13-16
32051500-7	2021	4-methyl-benzophenone (4-MBP) was detectable in 11% of the seminal fluid samples while in &lt;5% of the urine samples.	sulisobenzone	0-21	myelin basic protein	Homo sapiens	25-28
33099281-6	2021	Combining the previously published oligodendrocyte maturation assay (NPC6) with large-scale transcriptomics, we describe TBBPA as a TH disruptor impairing human OL maturation in vitro by dysregulation of oligodendrogenesis-associated genes (i.e. MBP, KLF9 and EGR1).	tetrabromobisphenol A	121-126	myelin basic protein	Homo sapiens	246-249
33189883-9	2021	Expression of mRNAs for proteins specific to more mature forms of OL lineage (platelet-derived growth factor alpha (PDGFRalpha) and myelin basic protein (MBP) was lower in the EtOH group than in controls.	Ethanol	176-180	myelin basic protein	Homo sapiens	132-152
33189883-9	2021	Expression of mRNAs for proteins specific to more mature forms of OL lineage (platelet-derived growth factor alpha (PDGFRalpha) and myelin basic protein (MBP) was lower in the EtOH group than in controls.	Ethanol	176-180	myelin basic protein	Homo sapiens	154-157
33432316-4	2021	MBP-ScFv proves to be a valuable modular platform to synergistically bind maltose-derivatized therapeutic cargos through the MBP, while preserving the targeting competences provided by the ScFv.	Maltose	74-81	myelin basic protein	Homo sapiens	0-3
33432316-4	2021	MBP-ScFv proves to be a valuable modular platform to synergistically bind maltose-derivatized therapeutic cargos through the MBP, while preserving the targeting competences provided by the ScFv.	Maltose	74-81	myelin basic protein	Homo sapiens	125-128
33432316-5	2021	The methodology has been tested by using a mutated maltose-binding protein (MBP I334W) with an enhanced affinity toward maltose and an ScFv coding sequence toward the human epidermal growth factor receptor 2 (HER2).	Maltose	51-58	myelin basic protein	Homo sapiens	76-79
33432316-6	2021	Non-covalent binding complexes of the resulting MBP-ScFv fusion protein with diverse maltosylated therapeutic cargos (a near-infrared dye, a maltosylated supramolecular beta-cyclodextrin container for doxorubicin, and non-viral polyplex gene vector) were easily prepared and characterized.	betadex	169-186	myelin basic protein	Homo sapiens	48-51
33432316-6	2021	Non-covalent binding complexes of the resulting MBP-ScFv fusion protein with diverse maltosylated therapeutic cargos (a near-infrared dye, a maltosylated supramolecular beta-cyclodextrin container for doxorubicin, and non-viral polyplex gene vector) were easily prepared and characterized.	Doxorubicin	201-212	myelin basic protein	Homo sapiens	48-51
33392935-6	2021	The approximate genome size of strains CY05T and H18S-6 were 4.86 and 5.04 Mbp, the genomic G + C content of them were 54.2 and 54.5%, respectively.	h18s	49-53	myelin basic protein	Homo sapiens	75-78
33245472-8	2021	MBP and Olig-1 expression were increased significantly in CoQ10 treated group compare to the CPZ-intoxicated group.	Cuprizone	93-96	myelin basic protein	Homo sapiens	0-3
33008588-9	2020	The K10H16 peptide bound to MBP-GFP and transported it into intracellular lysosomes.	k10h16	4-10	myelin basic protein	Homo sapiens	28-31
33263328-2	2020	Here, the high-affinity copper(II)-binding tripeptide GHK was fused to the N-terminus of a GFP variant and an MBP-FG peptide fusion.	tripeptide K-26	43-53	myelin basic protein	Homo sapiens	110-113
33263328-2	2020	Here, the high-affinity copper(II)-binding tripeptide GHK was fused to the N-terminus of a GFP variant and an MBP-FG peptide fusion.	cupric ion	24-34	myelin basic protein	Homo sapiens	110-113
32619644-6	2020	In one strategy, a MBP-TEV-Streptavidin fusion protein is immobilized on biotin-functionalized SPIONs.	Biotin	73-79	myelin basic protein	Homo sapiens	19-22
32959447-2	2020	Remarkably, these photoinitiators (noted monofunctional benzophenone-triphenylamine (MBP-TPA) and trifunctional benzophenone-triphenylamine (TBP-TPA)) are designed and developed for the photopolymerization under light-emitting diodes (LEDs).	benzophenone-triphenylamine	56-83	myelin basic protein	Homo sapiens	85-88
31747459-3	2020	It was shown previously that in contrast to classical enzymes, preparations of one of the light chains (NGTA2-Me-pro-Tr) showed two optimal pH values, two optimal concentrations of metal ions and two Km values for MBP.	triazolium-bis(triazole)tetrachlororuthenate(III)	104-119	myelin basic protein	Homo sapiens	214-217
31747459-7	2020	The analysis allowed us to identify the protein sequences of NGTA2-Me-pro-Tr responsible for serine-like activity, the binding of MBP, chelation of metal ions and catalysis directly.	triazolium-bis(triazole)tetrachlororuthenate(III)	61-76	myelin basic protein	Homo sapiens	130-133
33097924-6	2020	The addition of doxycycline for 10 d results in >60% of cells being O4-expressing OPCs, of which 20% co-express the mature OL marker myelin basic protein (MBP).	Doxycycline	16-27	myelin basic protein	Homo sapiens	133-153
33097924-6	2020	The addition of doxycycline for 10 d results in >60% of cells being O4-expressing OPCs, of which 20% co-express the mature OL marker myelin basic protein (MBP).	Doxycycline	16-27	myelin basic protein	Homo sapiens	155-158
32396017-10	2020	Therefore, anthocyanin-rich blackcurrants might be beneficial for maintaining or improving cardiovascular health as an alternative to pharmaceutical medications.Abbreviations: Aix: augmentation index; BP: blood pressure; cfPWV: carotid-femoral pulse-wave velocity;  CVD: cardiovascular diseases; DBP: diastolic blood pressure;  faPWV: femoral-ankle pulse-wave velocity; FG: fasting glucose; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol; MBP: mean blood pressure; NZBC: New Zealand blackcurrant; PP: pulse pressure; SBP: systolic blood pressure; TG: triglycerides.	Anthocyanins	11-22	myelin basic protein	Homo sapiens	476-479
32017071-3	2020	We have developed recombinant maltose-binding protein (MBP)-fused proteins as artificial adhesion matrices to control human mesenchymal stem cell (hMSC) fate by using an integrin-independent heparin sulfate proteoglycans-mediated cell adhesion.	heparin proteoglycan	191-206	myelin basic protein	Homo sapiens	30-53
32017071-3	2020	We have developed recombinant maltose-binding protein (MBP)-fused proteins as artificial adhesion matrices to control human mesenchymal stem cell (hMSC) fate by using an integrin-independent heparin sulfate proteoglycans-mediated cell adhesion.	heparin proteoglycan	191-206	myelin basic protein	Homo sapiens	55-58
32650830-10	2020	A wide range of TMB (1.75-73.81 mutations/Mbp) was observed.	1,2,4,5-tetramethoxybenzene	16-19	myelin basic protein	Homo sapiens	42-45
32731205-1	2020	Strain effects have been widely addressed in monolayer black phosphorus~(MBP) due to their significant influence on the orbital hybridization of atoms.	Phosphorus	61-71	myelin basic protein	Homo sapiens	73-76
32731205-3	2020	The analytical study of the band gap in strained MBP demonstrates electronic phase transitions from semiconductor-to-semimetal/metal and semiconductor-to-insulator, in which both the compressive and tensile strains act linearly on the band gap alterations.	Metals	121-126	myelin basic protein	Homo sapiens	49-52
32335165-11	2020	Piperine treatment significantly reduced the gene expression level of TNF-alpha, IL1-beta, NF-kappaB, and glial activation in the injured area; however, the mRNA level of IL-10, Foxp3, BDNF and MBP were significantly increased.	piperine	0-8	myelin basic protein	Homo sapiens	194-197
32401689-10	2020	It was found that more than 95% of the DSBs are repaired within the first 24 h and the misrepaired DSB fraction increases rapidly with LET and reaches 15.8% at 60 keV/mum with an estimated chromosome aberration detection threshold of 3 Mbp.	1,2-di-(4-sulfamidophenyl)-4-butylpyrazolidine-3,5-dione	39-43	myelin basic protein	Homo sapiens	236-239
32578583-3	2020	Here, by utilising the binding of maltose to hydrogels constructed from photo-chemically cross-linked maltose binding protein (MBP), we investigate the effects of protein stabilisation at the molecular level on the macroscopic mechanical and structural properties of a protein-based hydrogel.	Maltose	34-41	myelin basic protein	Homo sapiens	127-130
32578583-3	2020	Here, by utilising the binding of maltose to hydrogels constructed from photo-chemically cross-linked maltose binding protein (MBP), we investigate the effects of protein stabilisation at the molecular level on the macroscopic mechanical and structural properties of a protein-based hydrogel.	Maltose	102-109	myelin basic protein	Homo sapiens	127-130
32578583-4	2020	Rheological measurements show an enhancement in the mechanical strength and energy dissipation of MBP hydrogels in the presence of maltose.	Maltose	131-138	myelin basic protein	Homo sapiens	98-101
31375779-7	2020	Immunization with MBP-derived altered peptide ligands also rescued chronic stress-induced deficits in p11, phosphorylated cyclic adenosine monophosphate response element binding protein, and brain-derived neurotrophic factor expression.	Cyclic AMP	122-152	myelin basic protein	Homo sapiens	18-21
32151947-9	2020	Curcumin improved myelination potential via increasing beta-III tubulin-/MBP+ cells (neuron-oligodendrocyte co-culture) and augmented fluoromyelin intensity and neurofilament/MBP+ neurons in vivo.	Curcumin	0-8	myelin basic protein	Homo sapiens	73-76
32151947-9	2020	Curcumin improved myelination potential via increasing beta-III tubulin-/MBP+ cells (neuron-oligodendrocyte co-culture) and augmented fluoromyelin intensity and neurofilament/MBP+ neurons in vivo.	Curcumin	0-8	myelin basic protein	Homo sapiens	175-178
32184402-6	2020	GSH levels correlated negatively with SBP, DBP and MBP values in all participants (p = 0.0010; p = 0.0350 and p = 0.0050) as well as with MBP values in high normal and grade 1 hypertension (p = 0.0290).	Glutathione	0-3	myelin basic protein	Homo sapiens	51-54
32224229-5	2020	The effects of lysolecithin injections were assessed in two ways: 1) the expression of myelin basic protein, a component of compacted myelin sheaths, was quantified using immunohistochemistry and 2) electron microscopy was used to obtain measurements of myelin thickness of individual axons as well as qualitative descriptions of the extent of damage to myelin and surrounding tissue.	Lysophosphatidylcholines	15-27	myelin basic protein	Homo sapiens	87-107
31937613-8	2020	TMB tended to be higher after EGFR-TKI treatment than before (3.3 4.1 mutations/Mbp, P = 0.0508).	1,2,4,5-tetramethoxybenzene	0-3	myelin basic protein	Homo sapiens	80-83
32028099-3	2020	Here, a nanoimmunosensor based on atomic force spectroscopy (AFS) successfully detected autoantibodies against the MBP85-99 peptide from myelin basic protein.	4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene	115-123	myelin basic protein	Homo sapiens	137-157
32184402-6	2020	GSH levels correlated negatively with SBP, DBP and MBP values in all participants (p = 0.0010; p = 0.0350 and p = 0.0050) as well as with MBP values in high normal and grade 1 hypertension (p = 0.0290).	Glutathione	0-3	myelin basic protein	Homo sapiens	138-141
32184402-7	2020	The levels of GSSG correlated positively with SBP, DBP and MBP values in all participants (p = 0.0410; p = 0.0330 and, p = 0.0220).	Glutathione Disulfide	14-18	myelin basic protein	Homo sapiens	59-62
33654738-4	2020	MBP-PKD1-5 is a fusion of the maltose binding protein with all five of the PKD domains of the AAVR receptor.	Maltose	30-37	myelin basic protein	Homo sapiens	0-3
32138362-13	2020	Decreases in PSS favoured the WA-MBP-LS group at posttest and follow-up.	pss	13-16	myelin basic protein	Homo sapiens	33-36
31881420-12	2020	The most highly weighted phthalate metabolites, associated with fine-motor functions among females, were MBP, MBZP, and MIBP, all non-DEHP phthalates.	phthalic acid	25-34	myelin basic protein	Homo sapiens	105-108
31976658-5	2020	Under the optimized conditions, the visual detection limits (vLODs) of peptide-MBP-based mICA could be obtained as 0.25 ng/mL for FB1, 3.0 ng/mL for ZEN, and 0.5 ng/mL for OTA within 10 min.	Zearalenone	149-152	myelin basic protein	Homo sapiens	79-82
32075304-4	2020	The circular chromosome (4.39 Mbp) of the strain CHu59-6-5T has 64.4% G+C content and contains 4240 genes, of which a total of 3918 genes (92.4%) were functionally assigned to the COG (clusters of orthologous groups) database.	Carbon	49-50	myelin basic protein	Homo sapiens	30-33
31995359-0	2020	Different Anomeric Sugar Bound States of MBP Resolved by a Cytolysin A Nanopore Tweezer.	Carbohydrates	19-24	myelin basic protein	Homo sapiens	41-44
31995359-4	2020	Our analysis reveal that these three states represented MBP bound to different isomers of reducing sugars.	Carbohydrates	99-105	myelin basic protein	Homo sapiens	56-59
31805269-0	2020	Myelin basic protein (MBP) charge variants show different sphingomyelin-mediated interactions with myelin-like lipid monolayers.	Sphingomyelins	58-71	myelin basic protein	Homo sapiens	0-20
31805269-0	2020	Myelin basic protein (MBP) charge variants show different sphingomyelin-mediated interactions with myelin-like lipid monolayers.	Sphingomyelins	58-71	myelin basic protein	Homo sapiens	22-25
31805269-3	2020	Our findings show that the electrostatic attraction between the positively charged proteins and negatively charged lipids in the myelin-like monolayers competes with the incorporation of MBP into regions directly bordering cholesterol-rich domains.	Cholesterol	223-234	myelin basic protein	Homo sapiens	187-190
31805269-6	2020	In contrast, MBP C8 is still incorporated near cholesterol-enriched regions without SM.	Cholesterol	47-58	myelin basic protein	Homo sapiens	13-16
31805269-8	2020	This phenomenon may be relevant for the correlation of higher amounts of MBP C8 in brains of adult MS patients and healthy children, in which the amount of SM is reduced compared to healthy adults.	Sphingomyelins	156-158	myelin basic protein	Homo sapiens	73-76
32025030-7	2020	We transferred the reaction sites from TG to an engineered tyrosine donor-acceptor pair in the unrelated bacterial maltose-binding protein (MBP), which yielded hormone production with an efficiency comparable to that of TG.	Tyrosine	59-67	myelin basic protein	Homo sapiens	115-138
32025030-7	2020	We transferred the reaction sites from TG to an engineered tyrosine donor-acceptor pair in the unrelated bacterial maltose-binding protein (MBP), which yielded hormone production with an efficiency comparable to that of TG.	Tyrosine	59-67	myelin basic protein	Homo sapiens	140-143
31841337-2	2020	Here, we present a small-angle neutron scattering (SANS) and neutron spin-echo spectroscopy (NSE) study on the structure and dynamics of the intrinsically disordered myelin basic protein (MBP) denatured by urea.	Urea	206-210	myelin basic protein	Homo sapiens	166-186
31841337-2	2020	Here, we present a small-angle neutron scattering (SANS) and neutron spin-echo spectroscopy (NSE) study on the structure and dynamics of the intrinsically disordered myelin basic protein (MBP) denatured by urea.	Urea	206-210	myelin basic protein	Homo sapiens	188-191
31841337-3	2020	SANS results show that urea-denatured MBP is more compact than ideal polymers, while its secondary structure content is entirely lost.	Urea	23-27	myelin basic protein	Homo sapiens	38-41
31841337-3	2020	SANS results show that urea-denatured MBP is more compact than ideal polymers, while its secondary structure content is entirely lost.	Polymers	69-77	myelin basic protein	Homo sapiens	38-41
31841337-4	2020	NSE experiments reveal concomitantly an increase of the relaxation time and of the amplitude of internal motions in urea-denatured MBP as compared to native MBP.	Urea	116-120	myelin basic protein	Homo sapiens	131-134
31841337-4	2020	NSE experiments reveal concomitantly an increase of the relaxation time and of the amplitude of internal motions in urea-denatured MBP as compared to native MBP.	Urea	116-120	myelin basic protein	Homo sapiens	157-160
32176957-8	2020	Hyperbaric oxygen improves mitochondrial function, inhibits lipid peroxidation transiently, impairs leukocyte adhesion to injured microvasculature, and reduces brain inflammation caused by the CO-induced adduct formation of myelin basic protein.	Oxygen	11-17	myelin basic protein	Homo sapiens	224-244
31735420-9	2020	Thermodynamic parameters demonstrated that MBP-aD interacted with anti-HBsAg and PAMAM G4, through van der Waals and hydrogen bonding.	PEG-PAMAM	81-86	myelin basic protein	Homo sapiens	43-46
31735420-9	2020	Thermodynamic parameters demonstrated that MBP-aD interacted with anti-HBsAg and PAMAM G4, through van der Waals and hydrogen bonding.	Hydrogen	117-125	myelin basic protein	Homo sapiens	43-46
31735420-10	2020	These analyses suggest that the weak interaction of MBP-aD and PAMAM G4 may form a potential bio-nanogate.	PEG-PAMAM	63-68	myelin basic protein	Homo sapiens	52-55
31735420-11	2020	It is hypothesized that the presence of anti-HBsAg has a higher affinity towards MBP-aD which may displace PAMAM G4 in the anti-HBsAg detection system.	PEG-PAMAM	107-112	myelin basic protein	Homo sapiens	81-84
31373370-11	2019	Excess iron increased hippocampal lipid peroxidation by 74% (P &lt; 0.05) and decreased MBP by 44% (P = 0.053).	Iron	7-11	myelin basic protein	Homo sapiens	88-91
32072023-4	2020	Two peptides corresponding to MBP residues 99-110 (MBP (99-110)) and ECP residues 29-45 (ECP (29-45)), respectively, induced degranulation of HCMCs and intracellular Ca2+ mobilization in MRGPRX2-expressing HEK293 cells in a concentration-dependent manner.	Calcium	166-170	myelin basic protein	Homo sapiens	30-33
32072023-4	2020	Two peptides corresponding to MBP residues 99-110 (MBP (99-110)) and ECP residues 29-45 (ECP (29-45)), respectively, induced degranulation of HCMCs and intracellular Ca2+ mobilization in MRGPRX2-expressing HEK293 cells in a concentration-dependent manner.	Calcium	166-170	myelin basic protein	Homo sapiens	51-54
32072023-5	2020	Stimulation with MBP (99-110) or ECP (29-45) induced the production of prostaglandin D2 by HCMCs.	Prostaglandin D2	71-87	myelin basic protein	Homo sapiens	17-20
31819781-0	2019	Thermodynamic Analysis of Myelin Basic Protein Adsorbed on Liquid Crystalline Dioleoylphosphatidylcholine Monolayer.	1,2-oleoylphosphatidylcholine	78-105	myelin basic protein	Homo sapiens	26-46
31819781-4	2019	Experimental results have demonstrated that the partition coefficient of the interaction between MBP and unsaturated phospholipid DOPC and the molecular area of MBP adsorbed on the monolayer film was calculated using the mass conservation equation.	1,2-oleoylphosphatidylcholine	130-134	myelin basic protein	Homo sapiens	97-100
31819781-5	2019	In addition, not only does the varying concentration of MBP in the subphase exerts significant effects on the arrangement and conformation of DOPC monolayer, it also has certain guiding significance to exploring the structural changes to biofilm supramolecular aggregates as well as the pathogenesis and treatment of related diseases.	1,2-oleoylphosphatidylcholine	142-146	myelin basic protein	Homo sapiens	56-59
31202958-7	2019	RESULTS: The administration of cuprizone resulted in increased protein nitration, DNA damage, and astrocyte and microglial immunoreactivity, a decrease in the density of oligodendrocytes and OPCs, together with altered structure of the Node of Ranvier and reduced myelin basic protein immunoreactivity.	Cuprizone	31-40	myelin basic protein	Homo sapiens	264-284
31349062-7	2019	Different regions within a tumor showed considerable spatial TMB variance in 30% (7 of 24) of the cases (maximum difference, 14.13 mut/Mbp).	1,2,4,5-tetramethoxybenzene	61-64	myelin basic protein	Homo sapiens	135-138
31320053-4	2019	More importantly, the CS/MBP/DOX (CMD) hydrogel exhibited a photothermal efficiency of 22.18% and 31.42% in the first and second near infrared light (NIR I and NIR II) biowindows respectively at a low MBP concentration (0.5 mg/mL).	Chitosan	22-24	myelin basic protein	Homo sapiens	25-28
31320053-4	2019	More importantly, the CS/MBP/DOX (CMD) hydrogel exhibited a photothermal efficiency of 22.18% and 31.42% in the first and second near infrared light (NIR I and NIR II) biowindows respectively at a low MBP concentration (0.5 mg/mL).	Chitosan	22-24	myelin basic protein	Homo sapiens	201-204
31320053-4	2019	More importantly, the CS/MBP/DOX (CMD) hydrogel exhibited a photothermal efficiency of 22.18% and 31.42% in the first and second near infrared light (NIR I and NIR II) biowindows respectively at a low MBP concentration (0.5 mg/mL).	Doxorubicin	29-32	myelin basic protein	Homo sapiens	25-28
31320053-4	2019	More importantly, the CS/MBP/DOX (CMD) hydrogel exhibited a photothermal efficiency of 22.18% and 31.42% in the first and second near infrared light (NIR I and NIR II) biowindows respectively at a low MBP concentration (0.5 mg/mL).	Doxorubicin	29-32	myelin basic protein	Homo sapiens	201-204
31500384-9	2019	In combination with the clinical DNMT inhibitor decitabine, OF could synergize the growth inhibition and MBP induction in U87MG cells.	Decitabine	48-58	myelin basic protein	Homo sapiens	105-108
30902718-4	2019	Three recombinant segments were successfully expressed in host strain Escherichia coli DH5alpha induced by IPTG (0.3 mM) at 37  C for 4 h, respectively named MBP-FMBP-1, MBP-FMBP-2 and MBP-FMBP-3.	Isopropyl Thiogalactoside	107-111	myelin basic protein	Homo sapiens	158-161
31390799-4	2019	We used two drugs that stimulate myelin basic protein (MBP) expression (Clobetasol and Gefitinib) alone or combined with epidermal growth factor receptor (EGFR) or Retinoid X Receptor gamma (RXRgamma) gene silencing to decode the receptor signaling required for OPC differentiation in myelinating OLs.	Clobetasol	72-82	myelin basic protein	Homo sapiens	33-53
31390799-4	2019	We used two drugs that stimulate myelin basic protein (MBP) expression (Clobetasol and Gefitinib) alone or combined with epidermal growth factor receptor (EGFR) or Retinoid X Receptor gamma (RXRgamma) gene silencing to decode the receptor signaling required for OPC differentiation in myelinating OLs.	Clobetasol	72-82	myelin basic protein	Homo sapiens	55-58
31390799-4	2019	We used two drugs that stimulate myelin basic protein (MBP) expression (Clobetasol and Gefitinib) alone or combined with epidermal growth factor receptor (EGFR) or Retinoid X Receptor gamma (RXRgamma) gene silencing to decode the receptor signaling required for OPC differentiation in myelinating OLs.	Gefitinib	87-96	myelin basic protein	Homo sapiens	55-58
31390799-7	2019	Consistent with this, Clobetasol and Gefitinib co-treatment, by co-regulating RXRgamma, MBP and phosphatidylinositol 4,5-bisphosphate (PIP2) levels, maximizes synthetic axon engagement.	Clobetasol	22-32	myelin basic protein	Homo sapiens	88-91
31390799-7	2019	Consistent with this, Clobetasol and Gefitinib co-treatment, by co-regulating RXRgamma, MBP and phosphatidylinositol 4,5-bisphosphate (PIP2) levels, maximizes synthetic axon engagement.	Gefitinib	37-46	myelin basic protein	Homo sapiens	88-91
30902718-5	2019	MTT assay showed that only MBP-FMBP-2 possessed significant anti-colon cancer activity, and its anti-colon cancer activity was equivalent to FMBP.	monooxyethylene trimethylolpropane tristearate	0-3	myelin basic protein	Homo sapiens	27-30
30902718-6	2019	Further, the results showed that MBP-FMBP-2 significantly reversed the 5-Fu resistance in human colorectal cancer HCT-8/Fu cell through inhibiting cell proliferation, promoting cell apoptosis and increasing the intracellular accumulation of 5-Fu.	Fluorouracil	71-75	myelin basic protein	Homo sapiens	33-36
30902718-6	2019	Further, the results showed that MBP-FMBP-2 significantly reversed the 5-Fu resistance in human colorectal cancer HCT-8/Fu cell through inhibiting cell proliferation, promoting cell apoptosis and increasing the intracellular accumulation of 5-Fu.	Fluorouracil	241-245	myelin basic protein	Homo sapiens	33-36
30837563-8	2019	Furthermore, we confirmed that OS significantly increased expression levels of both Krox20 and MBP in SC-motor neuron (MN) coculture, which was notably prevented by pharmacological intervention with Ca2+.	Osmium	31-33	myelin basic protein	Homo sapiens	95-98
30950267-3	2019	In previous work, we presented experimental evidence that macromolecular crowders acted competitively in inhibiting the binding of maltose binding protein (MBP) with its ligand maltose.	Maltose	131-138	myelin basic protein	Homo sapiens	156-159
30950267-3	2019	In previous work, we presented experimental evidence that macromolecular crowders acted competitively in inhibiting the binding of maltose binding protein (MBP) with its ligand maltose.	Maltose	177-184	myelin basic protein	Homo sapiens	156-159
30950267-5	2019	Maltose binds to the cleft between two lobes of MBP, and in a series of mutants, the affinities increased with an increase in the extent of lobe closure.	Maltose	0-7	myelin basic protein	Homo sapiens	48-51
30950267-8	2019	Competition between the ligand and crowder, as indicated by fitting of titration data and directly by nuclear magnetic resonance spectroscopy, and their similar preferences for closed MBP conformations further suggest the scenario in which the crowder, like maltose, preferentially binds to the interlobe cleft of MBP.	Maltose	258-265	myelin basic protein	Homo sapiens	184-187
30950267-8	2019	Competition between the ligand and crowder, as indicated by fitting of titration data and directly by nuclear magnetic resonance spectroscopy, and their similar preferences for closed MBP conformations further suggest the scenario in which the crowder, like maltose, preferentially binds to the interlobe cleft of MBP.	Maltose	258-265	myelin basic protein	Homo sapiens	314-317
30865465-2	2019	Glatiramer acetate was originally developed to emulate human myelin basic protein, which contains four different residues [alanine (A), glutamic acid (E), tyrosine (T), and lysine (K)].	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	61-81
30865465-2	2019	Glatiramer acetate was originally developed to emulate human myelin basic protein, which contains four different residues [alanine (A), glutamic acid (E), tyrosine (T), and lysine (K)].	Alanine	123-130	myelin basic protein	Homo sapiens	61-81
30865465-2	2019	Glatiramer acetate was originally developed to emulate human myelin basic protein, which contains four different residues [alanine (A), glutamic acid (E), tyrosine (T), and lysine (K)].	Glutamic Acid	136-149	myelin basic protein	Homo sapiens	61-81
30865465-2	2019	Glatiramer acetate was originally developed to emulate human myelin basic protein, which contains four different residues [alanine (A), glutamic acid (E), tyrosine (T), and lysine (K)].	Tyrosine	155-163	myelin basic protein	Homo sapiens	61-81
30865465-2	2019	Glatiramer acetate was originally developed to emulate human myelin basic protein, which contains four different residues [alanine (A), glutamic acid (E), tyrosine (T), and lysine (K)].	Lysine	173-179	myelin basic protein	Homo sapiens	61-81
30837563-5	2019	In addition, OS also markedly promoted the expression of both Krox20 and myelin basic protein (MBP) in SC culture medium containing dBcAMP/NRG1, which induced differentiation.	Osmium	13-15	myelin basic protein	Homo sapiens	73-93
30837563-5	2019	In addition, OS also markedly promoted the expression of both Krox20 and myelin basic protein (MBP) in SC culture medium containing dBcAMP/NRG1, which induced differentiation.	Osmium	13-15	myelin basic protein	Homo sapiens	95-98
30837563-5	2019	In addition, OS also markedly promoted the expression of both Krox20 and myelin basic protein (MBP) in SC culture medium containing dBcAMP/NRG1, which induced differentiation.	Bucladesine	132-138	myelin basic protein	Homo sapiens	73-93
30837563-5	2019	In addition, OS also markedly promoted the expression of both Krox20 and myelin basic protein (MBP) in SC culture medium containing dBcAMP/NRG1, which induced differentiation.	Bucladesine	132-138	myelin basic protein	Homo sapiens	95-98
31205020-5	2019	Crystal structures were determined of MBP-betaFXIIaHis in complex with the inhibitor D-Phe-Pro-Arg chloromethyl ketone (PPACK) and of betaFXIIaHis in isolation.	Phenylalanyl-prolyl-arginine	85-98	myelin basic protein	Homo sapiens	38-41
31205020-5	2019	Crystal structures were determined of MBP-betaFXIIaHis in complex with the inhibitor D-Phe-Pro-Arg chloromethyl ketone (PPACK) and of betaFXIIaHis in isolation.	1,3-Dichloroacetone	99-118	myelin basic protein	Homo sapiens	38-41
31205020-5	2019	Crystal structures were determined of MBP-betaFXIIaHis in complex with the inhibitor D-Phe-Pro-Arg chloromethyl ketone (PPACK) and of betaFXIIaHis in isolation.	phenylalanyl-prolyl-arginine-chloromethyl ketone	120-125	myelin basic protein	Homo sapiens	38-41
31058187-3	2019	Poly-L-Arginine (PLA) is a kind of synthetic cationic polypeptides, which is widely used to mimic the effects of MBP on epithelial cells in vitro.	polyarginine	0-15	myelin basic protein	Homo sapiens	113-116
31058187-3	2019	Poly-L-Arginine (PLA) is a kind of synthetic cationic polypeptides, which is widely used to mimic the effects of MBP on epithelial cells in vitro.	polyarginine	17-20	myelin basic protein	Homo sapiens	113-116
30553827-6	2019	In a glial cell model sNF96.2 cells, miconazole restored the TOCP-inhibited MBP expression, and promoted cell differentiation as well as cell migration by inhibiting the activation of ErbB/Akt signaling pathway.	Miconazole	37-47	myelin basic protein	Homo sapiens	76-79
30553827-6	2019	In a glial cell model sNF96.2 cells, miconazole restored the TOCP-inhibited MBP expression, and promoted cell differentiation as well as cell migration by inhibiting the activation of ErbB/Akt signaling pathway.	tri-o-cresyl phosphate	61-65	myelin basic protein	Homo sapiens	76-79
30755303-0	2019	Ionic strength and calcium regulate membrane interactions of myelin basic protein and the cytoplasmic domain of myelin protein zero.	Calcium	19-26	myelin basic protein	Homo sapiens	61-81
30840612-8	2019	Furthermore, caffeine or DPCPX improved the expression MBP and CNPase proteins after hypoxia stimulation, which resulted in the morphological maturation of OLs.	Caffeine	13-21	myelin basic protein	Homo sapiens	55-58
30840612-8	2019	Furthermore, caffeine or DPCPX improved the expression MBP and CNPase proteins after hypoxia stimulation, which resulted in the morphological maturation of OLs.	1,3-dipropyl-8-cyclopentylxanthine	25-30	myelin basic protein	Homo sapiens	55-58
30112774-4	2019	Approximately 82% electrophoretically homogeneous SCZ IgGs purified using several affinity sorbents including Sepharose with immobilized MBP hydrolyze specifically only MBP but not many other tested proteins.	Sepharose	110-119	myelin basic protein	Homo sapiens	169-172
30551913-9	2019	Significantly (alpha &lt;= 0.05) decreased in vivo antioxidant enzyme activities, increased brain levels of MDA and H2O2, structural damage to myelin sheaths and decreased expression of MBP were also observed in the NaO3V group (D), however, co-administration of beta-sitosterol reduced these pathologic features.	nao3v	216-221	myelin basic protein	Homo sapiens	186-189
30476049-7	2019	Large (up to 12 Mbp) genomes of planctomycetes encode wide repertoires of carbohydrate-active enzymes including many unclassified putative glycoside hydrolases, which suggests the presence of extremely high glycolytic potential in these bacteria.	Carbohydrates	74-86	myelin basic protein	Homo sapiens	16-19
31038378-2	2019	Glatiramer acetate (GA) is the most commonly used drug for Multiple sclerosis (MS) patients that exerts an immunomodulatory effect against Myelin basic protein (MBP) antigen.	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	139-159
31038378-2	2019	Glatiramer acetate (GA) is the most commonly used drug for Multiple sclerosis (MS) patients that exerts an immunomodulatory effect against Myelin basic protein (MBP) antigen.	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	161-164
31038378-2	2019	Glatiramer acetate (GA) is the most commonly used drug for Multiple sclerosis (MS) patients that exerts an immunomodulatory effect against Myelin basic protein (MBP) antigen.	Glatiramer Acetate	20-22	myelin basic protein	Homo sapiens	139-159
31038378-2	2019	Glatiramer acetate (GA) is the most commonly used drug for Multiple sclerosis (MS) patients that exerts an immunomodulatory effect against Myelin basic protein (MBP) antigen.	Glatiramer Acetate	20-22	myelin basic protein	Homo sapiens	161-164
30446350-10	2019	We further link RSV to the up-regulation of other genes involved in myelination including the glial specific transcription factors POU3F1, POU3F2, and myelin basic protein (MBP).	Resveratrol	16-19	myelin basic protein	Homo sapiens	151-171
30520632-6	2019	Our results are the first to demonstrate plausible mechanistic links between ERE activation in the heart valves by BPA"s reactive metabolite MBP and the development of valvular-cardiovascular disease states.	bisphenol A	115-118	myelin basic protein	Homo sapiens	141-144
29362509-4	2019	Structural comparison of docked metabolites with DRB1*15:01 and DRB1*15:03 complexed with MBP revealed that PhenylalanineMBP92 allows binding of metabolites in the P4 pocket of DRB1*15:01 but ValineMBP89 abrogates metabolite binding in the P1 pocket.	valinembp89	192-203	myelin basic protein	Homo sapiens	90-93
30445309-4	2019	The results demonstrate that Bilobalide improved behavioral abnormality and promoted remyelination in the corpus callosum by using Luxol Fast Blue, Black Gold II and myelin basic protein (MBP) staining.	bilobalide	29-39	myelin basic protein	Homo sapiens	166-186
30445309-4	2019	The results demonstrate that Bilobalide improved behavioral abnormality and promoted remyelination in the corpus callosum by using Luxol Fast Blue, Black Gold II and myelin basic protein (MBP) staining.	bilobalide	29-39	myelin basic protein	Homo sapiens	188-191
30391262-6	2019	RESULTS: Immunostaining of choline acetyltransferase and myelin basic protein can be combined together and results show a good contrast between the light brown of the choline acetyltransferase reaction product and the green of myelin basic protein reaction product.	Choline	27-34	myelin basic protein	Homo sapiens	227-247
30391262-6	2019	RESULTS: Immunostaining of choline acetyltransferase and myelin basic protein can be combined together and results show a good contrast between the light brown of the choline acetyltransferase reaction product and the green of myelin basic protein reaction product.	Choline	167-174	myelin basic protein	Homo sapiens	57-77
30391262-12	2019	CONCLUSIONS: Routine combination of choline acetyltransferase and myelin basic protein immunostaining provides a highly specific, highly contrasted paraffin-embedded sections where optical differentiation of myelinated motor fibers is easy and straightforward.	Paraffin	148-156	myelin basic protein	Homo sapiens	66-86
30446350-10	2019	We further link RSV to the up-regulation of other genes involved in myelination including the glial specific transcription factors POU3F1, POU3F2, and myelin basic protein (MBP).	Resveratrol	16-19	myelin basic protein	Homo sapiens	173-176
30237570-8	2019	Deficits in MBP immunostaining of the preterm hippocampus and subcortical white matter were also ameliorated in animals receiving ganaxolone.	ganaxolone	130-140	myelin basic protein	Homo sapiens	12-15
30079618-7	2018	Roscovitine, an ATP-competitive CDK5 inhibitor, disrupted localization of the expressed MBP peptide.	Roscovitine	0-11	myelin basic protein	Homo sapiens	88-91
30416422-7	2018	OPCs produce 2-arachidonoylglycerol (2-AG), stimulating cannabinoid receptor-mediated ERK pathways responsible for differentiation to arborized, myelin basic protein (MBP)-producing oligodendrocytes.	glyceryl 2-arachidonate	13-35	myelin basic protein	Homo sapiens	145-165
30416422-7	2018	OPCs produce 2-arachidonoylglycerol (2-AG), stimulating cannabinoid receptor-mediated ERK pathways responsible for differentiation to arborized, myelin basic protein (MBP)-producing oligodendrocytes.	glyceryl 2-arachidonate	13-35	myelin basic protein	Homo sapiens	167-170
30416422-7	2018	OPCs produce 2-arachidonoylglycerol (2-AG), stimulating cannabinoid receptor-mediated ERK pathways responsible for differentiation to arborized, myelin basic protein (MBP)-producing oligodendrocytes.	glyceryl 2-arachidonate	37-41	myelin basic protein	Homo sapiens	145-165
30416422-7	2018	OPCs produce 2-arachidonoylglycerol (2-AG), stimulating cannabinoid receptor-mediated ERK pathways responsible for differentiation to arborized, myelin basic protein (MBP)-producing oligodendrocytes.	glyceryl 2-arachidonate	37-41	myelin basic protein	Homo sapiens	167-170
29803151-8	2018	These results suggested that nanofibers with lignin copolymers promoted cell proliferation of both BMSCs and Schwann cells, enhanced myelin basic protein expressions of Schwann cells and stimulated neurite outgrowth of DRG neurons.	lignin copolymers	45-62	myelin basic protein	Homo sapiens	133-153
30245469-9	2018	However, melatonin treatment significantly increased MBP immunoreactivity and numbers of Rip-immunoreactive oligodendrocytes in the ischemic CA1.	Melatonin	9-18	myelin basic protein	Homo sapiens	53-56
29731309-5	2018	Autistic children with high MBP-Ab levels were characterized by 28% higher serum Mn and lower Mg concentration.	Magnesium	94-96	myelin basic protein	Homo sapiens	28-31
29731309-10	2018	Serum Cd and Mn levels were significant positive predictors of anti-MBP-Ab levels, whereas Mg levels had a negative impact on anti-MBP-Ab values.	Cadmium	6-8	myelin basic protein	Homo sapiens	68-71
29731309-10	2018	Serum Cd and Mn levels were significant positive predictors of anti-MBP-Ab levels, whereas Mg levels had a negative impact on anti-MBP-Ab values.	Magnesium	91-93	myelin basic protein	Homo sapiens	131-134
30380295-0	2018	Evaluation of Maltose Binding Protein-Tagged hATR Kinase Domain Catalytic Activity with p53 Ser-15 Phosphorylation.	Serine	92-95	myelin basic protein	Homo sapiens	14-37
30380295-6	2018	Introduction of a solubility partner, i.e., maltose binding protein (MBP), at the N-terminus of the ATR kinase domain generated a soluble form of the protein, i.e., MBP-tagged hATR kinase domain (MBP-ATR-6X His), which was found to be catalytically active, as assessed by substrate p53 Ser-15 phosphorylation (EPPLSQEAFADLWKK).	Histidine	207-210	myelin basic protein	Homo sapiens	44-67
30380295-6	2018	Introduction of a solubility partner, i.e., maltose binding protein (MBP), at the N-terminus of the ATR kinase domain generated a soluble form of the protein, i.e., MBP-tagged hATR kinase domain (MBP-ATR-6X His), which was found to be catalytically active, as assessed by substrate p53 Ser-15 phosphorylation (EPPLSQEAFADLWKK).	Histidine	207-210	myelin basic protein	Homo sapiens	69-72
30380295-6	2018	Introduction of a solubility partner, i.e., maltose binding protein (MBP), at the N-terminus of the ATR kinase domain generated a soluble form of the protein, i.e., MBP-tagged hATR kinase domain (MBP-ATR-6X His), which was found to be catalytically active, as assessed by substrate p53 Ser-15 phosphorylation (EPPLSQEAFADLWKK).	Histidine	207-210	myelin basic protein	Homo sapiens	165-168
30380295-6	2018	Introduction of a solubility partner, i.e., maltose binding protein (MBP), at the N-terminus of the ATR kinase domain generated a soluble form of the protein, i.e., MBP-tagged hATR kinase domain (MBP-ATR-6X His), which was found to be catalytically active, as assessed by substrate p53 Ser-15 phosphorylation (EPPLSQEAFADLWKK).	Histidine	207-210	myelin basic protein	Homo sapiens	165-168
30380295-6	2018	Introduction of a solubility partner, i.e., maltose binding protein (MBP), at the N-terminus of the ATR kinase domain generated a soluble form of the protein, i.e., MBP-tagged hATR kinase domain (MBP-ATR-6X His), which was found to be catalytically active, as assessed by substrate p53 Ser-15 phosphorylation (EPPLSQEAFADLWKK).	Serine	286-289	myelin basic protein	Homo sapiens	44-67
30380295-6	2018	Introduction of a solubility partner, i.e., maltose binding protein (MBP), at the N-terminus of the ATR kinase domain generated a soluble form of the protein, i.e., MBP-tagged hATR kinase domain (MBP-ATR-6X His), which was found to be catalytically active, as assessed by substrate p53 Ser-15 phosphorylation (EPPLSQEAFADLWKK).	Serine	286-289	myelin basic protein	Homo sapiens	69-72
30380295-6	2018	Introduction of a solubility partner, i.e., maltose binding protein (MBP), at the N-terminus of the ATR kinase domain generated a soluble form of the protein, i.e., MBP-tagged hATR kinase domain (MBP-ATR-6X His), which was found to be catalytically active, as assessed by substrate p53 Ser-15 phosphorylation (EPPLSQEAFADLWKK).	Serine	286-289	myelin basic protein	Homo sapiens	165-168
30380295-6	2018	Introduction of a solubility partner, i.e., maltose binding protein (MBP), at the N-terminus of the ATR kinase domain generated a soluble form of the protein, i.e., MBP-tagged hATR kinase domain (MBP-ATR-6X His), which was found to be catalytically active, as assessed by substrate p53 Ser-15 phosphorylation (EPPLSQEAFADLWKK).	Serine	286-289	myelin basic protein	Homo sapiens	165-168
30218783-11	2018	A low dose of GSK247246 (7 mg/kg) lead to a recovery in protein expression of markers of myelin (density of Myelin Basic Protein, MBP &amp; Proteolipid Proteins, PLP) and a reduction in macro- and microgliosis (density of ionising adaptor protein, IBA1 &amp; glial fibrillary acid protein, GFAP).	gsk247246	14-23	myelin basic protein	Homo sapiens	108-128
30218783-11	2018	A low dose of GSK247246 (7 mg/kg) lead to a recovery in protein expression of markers of myelin (density of Myelin Basic Protein, MBP &amp; Proteolipid Proteins, PLP) and a reduction in macro- and microgliosis (density of ionising adaptor protein, IBA1 &amp; glial fibrillary acid protein, GFAP).	gsk247246	14-23	myelin basic protein	Homo sapiens	130-133
30052927-4	2018	Collectively, these HS-MEs contribute to a total of 14.2 Mbp net genome sequence increase.	hs-mes	20-26	myelin basic protein	Homo sapiens	57-60
30004675-5	2018	Even in its MG state, MBP is known to still bind its ligand maltose.	Magnesium	12-14	myelin basic protein	Homo sapiens	22-25
30004675-5	2018	Even in its MG state, MBP is known to still bind its ligand maltose.	Maltose	60-67	myelin basic protein	Homo sapiens	22-25
30004675-12	2018	Measurements show a defined structure around the binding pocket of MBP in MG, which explains maltose binding.	Maltose	93-100	myelin basic protein	Homo sapiens	67-70
30004675-13	2018	A new and important finding is that in both states ligand-free MBP can be found in open and closed form, while ligand-bound MBP appears only in closed form because of maltose binding.	Maltose	167-174	myelin basic protein	Homo sapiens	124-127
30079618-7	2018	Roscovitine, an ATP-competitive CDK5 inhibitor, disrupted localization of the expressed MBP peptide.	Adenosine Triphosphate	16-19	myelin basic protein	Homo sapiens	88-91
29954845-6	2018	Notably, MBP84-104 caused neither cell apoptosis nor affected the total cellular ATP levels, but repressed the aerobic glycolysis (lactic acid fermentation) and decreased the l-lactate/d-glucose ratio (also termed as the Warburg effect) in normal and cancer cells.	Adenosine Triphosphate	81-84	myelin basic protein	Homo sapiens	9-12
30009599-5	2018	Herein, the picolinic acid MBP is used as a case study for the development of MBP isosteres (so-called MBIs).	picolinic acid	12-26	myelin basic protein	Homo sapiens	27-30
30009599-5	2018	Herein, the picolinic acid MBP is used as a case study for the development of MBP isosteres (so-called MBIs).	picolinic acid	12-26	myelin basic protein	Homo sapiens	78-81
30131763-6	2018	Results: Patients in the increased BBB permeability group had significantly higher EDSS scores, anti-aquporin-4 immunoglobulin G titers, more dense cerebrospinal fluid protein concentrations, white blood cell counts, myelin basic protein levels and more dense complement 3 concentrations than found in the comparative normal BBB permeability group.	1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL)-6-HYDROXYPYRIMIDINE-2,4(1H,3H)-DIONE	35-38	myelin basic protein	Homo sapiens	217-237
29954845-6	2018	Notably, MBP84-104 caused neither cell apoptosis nor affected the total cellular ATP levels, but repressed the aerobic glycolysis (lactic acid fermentation) and decreased the l-lactate/d-glucose ratio (also termed as the Warburg effect) in normal and cancer cells.	Lactic Acid	131-142	myelin basic protein	Homo sapiens	9-12
29954845-6	2018	Notably, MBP84-104 caused neither cell apoptosis nor affected the total cellular ATP levels, but repressed the aerobic glycolysis (lactic acid fermentation) and decreased the l-lactate/d-glucose ratio (also termed as the Warburg effect) in normal and cancer cells.	L-lactate	175-184	myelin basic protein	Homo sapiens	9-12
29954845-6	2018	Notably, MBP84-104 caused neither cell apoptosis nor affected the total cellular ATP levels, but repressed the aerobic glycolysis (lactic acid fermentation) and decreased the l-lactate/d-glucose ratio (also termed as the Warburg effect) in normal and cancer cells.	Deuterium	24-25	myelin basic protein	Homo sapiens	9-12
29954845-6	2018	Notably, MBP84-104 caused neither cell apoptosis nor affected the total cellular ATP levels, but repressed the aerobic glycolysis (lactic acid fermentation) and decreased the l-lactate/d-glucose ratio (also termed as the Warburg effect) in normal and cancer cells.	Glucose	187-194	myelin basic protein	Homo sapiens	9-12
29851467-5	2018	The MBP binding site is loaded with dye or drug conjugates of the maltose analogue beta-cyclodextrin (betaCD) to yield a QD-MBP-betaCD ensemble conjugate.	Maltose	66-73	myelin basic protein	Homo sapiens	4-7
29851467-5	2018	The MBP binding site is loaded with dye or drug conjugates of the maltose analogue beta-cyclodextrin (betaCD) to yield a QD-MBP-betaCD ensemble conjugate.	betadex	83-100	myelin basic protein	Homo sapiens	4-7
29851467-5	2018	The MBP binding site is loaded with dye or drug conjugates of the maltose analogue beta-cyclodextrin (betaCD) to yield a QD-MBP-betaCD ensemble conjugate.	betadex	102-108	myelin basic protein	Homo sapiens	4-7
29851467-7	2018	Microplate-based FRET assays demonstrated that the betaCD conjugate was released from the MBP binding pocket by maltose addition with an affinity that matched native MBP-maltose binding interactions.	betadex	51-57	myelin basic protein	Homo sapiens	90-93
29851467-7	2018	Microplate-based FRET assays demonstrated that the betaCD conjugate was released from the MBP binding pocket by maltose addition with an affinity that matched native MBP-maltose binding interactions.	betadex	51-57	myelin basic protein	Homo sapiens	166-169
29851467-7	2018	Microplate-based FRET assays demonstrated that the betaCD conjugate was released from the MBP binding pocket by maltose addition with an affinity that matched native MBP-maltose binding interactions.	Maltose	112-119	myelin basic protein	Homo sapiens	90-93
29851467-7	2018	Microplate-based FRET assays demonstrated that the betaCD conjugate was released from the MBP binding pocket by maltose addition with an affinity that matched native MBP-maltose binding interactions.	Maltose	170-177	myelin basic protein	Homo sapiens	166-169
29776406-16	2018	Moreover, linagliptin treatment after stroke decreased the presence of peptides derived from neurogranin and from an isoform of the myelin basic protein.	Linagliptin	10-21	myelin basic protein	Homo sapiens	132-152
29722987-0	2018	Interaction of Myelin Basic Protein with Myelin-like Lipid Monolayers at Air-Water Interface.	Water	77-82	myelin basic protein	Homo sapiens	15-35
29546986-7	2018	Moreover, we present the first direct evidence for formation of a CH   O hydrogen bond between an MBP and 5-methylcytosine by using experimental (NMR) and quantum mechanical chemical shift analysis of the mC methyl protons.	Hydrogen	73-81	myelin basic protein	Homo sapiens	98-101
29571859-2	2018	Myelin basic protein (MBP), which is one of the main compounds of CNS myelin, appears to be hypercitrullinated in the brain of patients with MS. We hypothesized that MS is associated with an increased release of citrulline from the brain.	Citrulline	212-222	myelin basic protein	Homo sapiens	0-20
29571859-2	2018	Myelin basic protein (MBP), which is one of the main compounds of CNS myelin, appears to be hypercitrullinated in the brain of patients with MS. We hypothesized that MS is associated with an increased release of citrulline from the brain.	Citrulline	212-222	myelin basic protein	Homo sapiens	22-25
29546986-7	2018	Moreover, we present the first direct evidence for formation of a CH   O hydrogen bond between an MBP and 5-methylcytosine by using experimental (NMR) and quantum mechanical chemical shift analysis of the mC methyl protons.	5-Methylcytosine	106-122	myelin basic protein	Homo sapiens	98-101
29571287-6	2018	RESULTS: We observed several changes in the white matter of animals treated with oxycodone: deformation of axonal tracks, reduction in size of axonal fascicles, loss of myelin basic protein and accumulation of amyloid precursor protein beta (beta-APP), suggesting axonal damages by chronic oxycodone.	Oxycodone	81-90	myelin basic protein	Homo sapiens	169-189
28470584-4	2018	Using a biochemical, immunohistochemical, and immunogold-silver staining for electron microscopy techniques, we found that MBP residue R23 (corresponding to human R25) was specifically citrullinated, was stained as intense punctae in the corpus callosum, the striatum, and the cerebellar white matter, and was predominantly localized in disorganized myelin in the brains of scrapie-infected mice.	Silver	57-63	myelin basic protein	Homo sapiens	123-126
29321208-4	2018	Using maltose-binding protein (MBP) as a model system, customized phage-display selections were performed to generate sABs that stabilize MBP in different conformational states, modulating ligand-binding affinity in competitive, allosteric, or peristeric manners.	sabs	118-122	myelin basic protein	Homo sapiens	6-29
29896511-2	2018	Here we describe data related to the investigation of the properties of the His6-MBP-VSQNY PIVQ-mApple recombinant protein substrate and its interactions with Ni-NTA magnetic beads, including the dependence of substrate attachment on incubation time and concentration.	ni-nta	159-165	myelin basic protein	Homo sapiens	81-84
29548403-9	2018	Activated membranes with high load capacity did not seem to have an influence on the methane oxidation process: MBP coupled with 220g/m2 and 360g/m2 membranes gave maximum MOR of 16.5gCH4/m2/hr and 17.4gCH4/m2/hr, respectively.	Methane	85-92	myelin basic protein	Homo sapiens	112-115
29321208-4	2018	Using maltose-binding protein (MBP) as a model system, customized phage-display selections were performed to generate sABs that stabilize MBP in different conformational states, modulating ligand-binding affinity in competitive, allosteric, or peristeric manners.	sabs	118-122	myelin basic protein	Homo sapiens	31-34
29321208-4	2018	Using maltose-binding protein (MBP) as a model system, customized phage-display selections were performed to generate sABs that stabilize MBP in different conformational states, modulating ligand-binding affinity in competitive, allosteric, or peristeric manners.	sabs	118-122	myelin basic protein	Homo sapiens	138-141
29321208-5	2018	We determined that the binding of a closed conformation-specific sAB (sAB-11M) to MBP in the absence of maltose is entropically driven, providing new insight into designing antibody-stabilized protein interactions.	sab	65-68	myelin basic protein	Homo sapiens	82-85
29321208-5	2018	We determined that the binding of a closed conformation-specific sAB (sAB-11M) to MBP in the absence of maltose is entropically driven, providing new insight into designing antibody-stabilized protein interactions.	sab	70-73	myelin basic protein	Homo sapiens	82-85
29321208-6	2018	Crystal structures of sABs bound to MBP, together with biophysical data, delineate the basis of free energy differences between different conformational states and confirm the use of the sABs as energy probes for dissecting enthalpic and entropic contributions to conformational transitions.	sabs	22-26	myelin basic protein	Homo sapiens	36-39
29321208-6	2018	Crystal structures of sABs bound to MBP, together with biophysical data, delineate the basis of free energy differences between different conformational states and confirm the use of the sABs as energy probes for dissecting enthalpic and entropic contributions to conformational transitions.	sabs	187-191	myelin basic protein	Homo sapiens	36-39
28963004-5	2018	Furthermore, four HE-MBP(Pyr)-fused proteins were purified by immobilized metal affinity chromatography to assess the affinity of HE with immobilized Ni2+.	Helium	18-20	myelin basic protein	Homo sapiens	21-24
29313334-2	2018	Based on the binding between the alpha-l-guluronic blocks of AG and calcium ions, the AG/MoS2/Bi2S3-poly(ethylene glycol) (MBP)/doxorubicin (DOX) solution formed a cross-linked hydrogel to simultaneously encapsulate MBP nanosheets and DOX within the hydrogel matrix.	Calcium	68-75	myelin basic protein	Homo sapiens	123-126
29313334-2	2018	Based on the binding between the alpha-l-guluronic blocks of AG and calcium ions, the AG/MoS2/Bi2S3-poly(ethylene glycol) (MBP)/doxorubicin (DOX) solution formed a cross-linked hydrogel to simultaneously encapsulate MBP nanosheets and DOX within the hydrogel matrix.	Doxorubicin	128-139	myelin basic protein	Homo sapiens	216-219
29313334-4	2018	The AG/MBP/DOX hydrogel exhibited excellent photothermal conversion properties with mass extinction coefficient of 45.1 L/g/cm and photothermal conversion efficiency of 42.7%.	Doxorubicin	11-14	myelin basic protein	Homo sapiens	7-10
29416501-8	2018	The in vivo study using a lysolecithin-induced demyelinating animal model also indicated that larger amounts of MBP+-OLGs and PLP+-OLGs derived from implanted Bcl11b-KD GPCs were present at the lesioned site of the white matter than in the scramble group.	Lysophosphatidylcholines	26-38	myelin basic protein	Homo sapiens	112-115
29295923-1	2018	We used hydrogen exchange-mass spectrometry (HX MS) and fluorescence to compare the folding of maltose binding protein (MBP) in free solution and in the GroEL/ES cavity.	Maltose	95-102	myelin basic protein	Homo sapiens	120-123
29295923-1	2018	We used hydrogen exchange-mass spectrometry (HX MS) and fluorescence to compare the folding of maltose binding protein (MBP) in free solution and in the GroEL/ES cavity.	Einsteinium	159-161	myelin basic protein	Homo sapiens	120-123
29103486-1	2018	We designed an injectable hydrogel by dissolving MoS2/Bi2S3-PEG (MBP), doxorubicin (DOX) and agar into water for the concurrent tumor photothermal and chemotherapy.	molybdenum disulfide	49-53	myelin basic protein	Homo sapiens	65-68
29103486-1	2018	We designed an injectable hydrogel by dissolving MoS2/Bi2S3-PEG (MBP), doxorubicin (DOX) and agar into water for the concurrent tumor photothermal and chemotherapy.	bi2s3-peg	54-63	myelin basic protein	Homo sapiens	65-68
29103486-1	2018	We designed an injectable hydrogel by dissolving MoS2/Bi2S3-PEG (MBP), doxorubicin (DOX) and agar into water for the concurrent tumor photothermal and chemotherapy.	Water	103-108	myelin basic protein	Homo sapiens	65-68
29103486-4	2018	The resultant Agar/MBP/DOX (AMD) hydrogel can act as a macro-vessel to retain the MBP nanosheet and DOX and restrict their access to body fluid circulation.	Doxorubicin	23-26	myelin basic protein	Homo sapiens	82-85
29103486-4	2018	The resultant Agar/MBP/DOX (AMD) hydrogel can act as a macro-vessel to retain the MBP nanosheet and DOX and restrict their access to body fluid circulation.	Doxorubicin	100-103	myelin basic protein	Homo sapiens	19-22
29051083-8	2018	In DRG cultures, LPA caused a significant reduction of myelin as demonstrated by both Sudan Black staining and immunocytochemical analysis of myelin basic protein.	lysophosphatidic acid	17-20	myelin basic protein	Homo sapiens	142-162
29017895-4	2018	Fructose consumption reduced the levels of the neuronal nuclear protein NeuN, Myelin Basic Protein, and the axonal growth-associated protein 43, concomitant with a decline in hippocampal weight.	Fructose	0-8	myelin basic protein	Homo sapiens	78-98
30306515-4	2018	However, intrafascicular lidocaine brought about macrophage migration into the damaged fascicle, Schwann cell proliferation, increased intensity of myelin basic protein, and shorten withdrawal time to mechanical stimuli.	Lidocaine	25-34	myelin basic protein	Homo sapiens	148-168
29216561-0	2018	Design, synthesis and evaluation of an anthraquinone derivative conjugated to myelin basic protein immunodominant (MBP85-99) epitope: Towards selective immunosuppression.	Anthraquinones	39-52	myelin basic protein	Homo sapiens	78-98
29216561-5	2018	The compound consists of the myelin basic protein (MBP) 85-99 immunodominant epitope (MBP85-99) coupled to an anthraquinone type molecule (AQ) via a disulfide (S-S) and 6 amino hexanoic acid (Ahx) residues (AQ-S-S-(Ahx)6MBP85-99).	Disulfides	149-158	myelin basic protein	Homo sapiens	29-49
29216561-5	2018	The compound consists of the myelin basic protein (MBP) 85-99 immunodominant epitope (MBP85-99) coupled to an anthraquinone type molecule (AQ) via a disulfide (S-S) and 6 amino hexanoic acid (Ahx) residues (AQ-S-S-(Ahx)6MBP85-99).	Disulfides	149-158	myelin basic protein	Homo sapiens	51-54
29216561-5	2018	The compound consists of the myelin basic protein (MBP) 85-99 immunodominant epitope (MBP85-99) coupled to an anthraquinone type molecule (AQ) via a disulfide (S-S) and 6 amino hexanoic acid (Ahx) residues (AQ-S-S-(Ahx)6MBP85-99).	Aminocaproic Acid	169-190	myelin basic protein	Homo sapiens	29-49
29216561-5	2018	The compound consists of the myelin basic protein (MBP) 85-99 immunodominant epitope (MBP85-99) coupled to an anthraquinone type molecule (AQ) via a disulfide (S-S) and 6 amino hexanoic acid (Ahx) residues (AQ-S-S-(Ahx)6MBP85-99).	Aminocaproic Acid	169-190	myelin basic protein	Homo sapiens	51-54
29216561-5	2018	The compound consists of the myelin basic protein (MBP) 85-99 immunodominant epitope (MBP85-99) coupled to an anthraquinone type molecule (AQ) via a disulfide (S-S) and 6 amino hexanoic acid (Ahx) residues (AQ-S-S-(Ahx)6MBP85-99).	Aminocaproates	192-195	myelin basic protein	Homo sapiens	29-49
29216561-5	2018	The compound consists of the myelin basic protein (MBP) 85-99 immunodominant epitope (MBP85-99) coupled to an anthraquinone type molecule (AQ) via a disulfide (S-S) and 6 amino hexanoic acid (Ahx) residues (AQ-S-S-(Ahx)6MBP85-99).	Aminocaproates	192-195	myelin basic protein	Homo sapiens	51-54
29216561-5	2018	The compound consists of the myelin basic protein (MBP) 85-99 immunodominant epitope (MBP85-99) coupled to an anthraquinone type molecule (AQ) via a disulfide (S-S) and 6 amino hexanoic acid (Ahx) residues (AQ-S-S-(Ahx)6MBP85-99).	aq-s-s	207-213	myelin basic protein	Homo sapiens	29-49
29216561-5	2018	The compound consists of the myelin basic protein (MBP) 85-99 immunodominant epitope (MBP85-99) coupled to an anthraquinone type molecule (AQ) via a disulfide (S-S) and 6 amino hexanoic acid (Ahx) residues (AQ-S-S-(Ahx)6MBP85-99).	aq-s-s	207-213	myelin basic protein	Homo sapiens	51-54
29302192-8	2018	Furthermore, the transcriptional regulatory network showed that DMGs such as Aristaless-related homeobox (ARX), damage-specific DNA binding protein 2 (DDB2), and myelin basic protein (MBP) had higher node degrees.	dmgs	64-68	myelin basic protein	Homo sapiens	162-182
29302192-8	2018	Furthermore, the transcriptional regulatory network showed that DMGs such as Aristaless-related homeobox (ARX), damage-specific DNA binding protein 2 (DDB2), and myelin basic protein (MBP) had higher node degrees.	dmgs	64-68	myelin basic protein	Homo sapiens	184-187
29035086-10	2017	In the presence of DAPT, the markers for neuronal (MAP2, NEFH); and glial (GFAP, GLUL, and MBP) lineages were significantly downregulated as seen via immunofluorescence and quantitative polymerase chain reaction, indicating the role of Notch in the tri-differentiation mechanism of NSCs as well.	dapt	19-23	myelin basic protein	Homo sapiens	91-94
29165378-4	2017	The main driving factors which influenced sediment phosphorus flux velocity in the sediment-water interface were sediment B-SO42-, B-MBN and A-MBP content.	Phosphorus	51-61	myelin basic protein	Homo sapiens	143-146
29050663-7	2017	We observed that, in a VitD deficient environment, EoL-1 cells produced high levels of the Eo-mediators, including MBP, EPX, ECP and EDN, which could be suppressed by the addition of calcitriol to the culture.	Calcitriol	183-193	myelin basic protein	Homo sapiens	115-118
29165378-4	2017	The main driving factors which influenced sediment phosphorus flux velocity in the sediment-water interface were sediment B-SO42-, B-MBN and A-MBP content.	Water	92-97	myelin basic protein	Homo sapiens	143-146
29250212-0	2017	Effects of Concentration and Surface Pressure on MBP Interaction with Cholesterol in Langmuir Films.	Cholesterol	70-81	myelin basic protein	Homo sapiens	49-52
29250212-1	2017	Predicting the mechanism of MBP binding to cholesterol is meaningful in understanding how MBP participate in lateral membrane organization.	Cholesterol	43-54	myelin basic protein	Homo sapiens	28-31
29250212-2	2017	The interaction of MBP with cholesterol monolayer was investigated at three surface pressures on 10 mM Tris-HCl buffer with the different concentrations of MBP.	Cholesterol	28-39	myelin basic protein	Homo sapiens	19-22
29250212-1	2017	Predicting the mechanism of MBP binding to cholesterol is meaningful in understanding how MBP participate in lateral membrane organization.	Cholesterol	43-54	myelin basic protein	Homo sapiens	90-93
28863941-6	2017	Oxidation of lipids was assessed by the formation of conjugated diene/triene and malondialdehyde, and oxidation of MBP was demonstrated by the bityrosine formation and by the change in protein mass.	dityrosine	143-153	myelin basic protein	Homo sapiens	115-118
29250212-2	2017	The interaction of MBP with cholesterol monolayer was investigated at three surface pressures on 10 mM Tris-HCl buffer with the different concentrations of MBP.	Tris hydrochloride	103-111	myelin basic protein	Homo sapiens	19-22
29250212-7	2017	These results provide more direct and convincing evidence for the MBP interaction with cholesterol.	Cholesterol	87-98	myelin basic protein	Homo sapiens	66-69
29250212-8	2017	The MBP-cholesterol interaction suggests a significant concentrations and surface pressure dependence and is probably governed by hydrogen bonds.	Cholesterol	8-19	myelin basic protein	Homo sapiens	4-7
29250212-8	2017	The MBP-cholesterol interaction suggests a significant concentrations and surface pressure dependence and is probably governed by hydrogen bonds.	Hydrogen	130-138	myelin basic protein	Homo sapiens	4-7
29250212-9	2017	The date presented could help to understand at least one of the molecular mechanisms through which MBP affects lateral organization of the cholesterol membrane.	Cholesterol	139-150	myelin basic protein	Homo sapiens	99-102
29095858-8	2017	Supporting a role for PLA2 in psychosine-induced cell death of oligodendrocytes and astrocytes, the results show inhibition of PLA2 attenuates psychosine-induced decrease in the expression of astrocyte marker vimentin as well as myelin basic protein (MBP), myelin oligodendrocyte glycoprotein (MOG) and the neuronal marker SMI-32 in organotypic slice cultures.	Psychosine	143-153	myelin basic protein	Homo sapiens	229-249
29095858-8	2017	Supporting a role for PLA2 in psychosine-induced cell death of oligodendrocytes and astrocytes, the results show inhibition of PLA2 attenuates psychosine-induced decrease in the expression of astrocyte marker vimentin as well as myelin basic protein (MBP), myelin oligodendrocyte glycoprotein (MOG) and the neuronal marker SMI-32 in organotypic slice cultures.	Psychosine	143-153	myelin basic protein	Homo sapiens	251-254
29068219-3	2017	For this study, we addressed the recalcitrant expression of BAPT by expressing it as a soluble maltose binding protein fusion (MBP-BAPT).	Maltose	95-102	myelin basic protein	Homo sapiens	127-130
29068219-5	2017	The turnover rate of MBP-BAPT was calculated for the product N-debenzoylpaclitaxel, a key intermediate to various bioactive paclitaxel analogues.	N-Debenzoyltaxol	61-82	myelin basic protein	Homo sapiens	21-24
29068219-5	2017	The turnover rate of MBP-BAPT was calculated for the product N-debenzoylpaclitaxel, a key intermediate to various bioactive paclitaxel analogues.	Paclitaxel	72-82	myelin basic protein	Homo sapiens	21-24
29068219-6	2017	MBP-BAPT also converted, albeit more slowly, 10-deacetylbaccatin III to N-deacyldocetaxel, a precursor of the pharmaceutical docetaxel.	n-deacyldocetaxel	72-89	myelin basic protein	Homo sapiens	0-3
29068219-6	2017	MBP-BAPT also converted, albeit more slowly, 10-deacetylbaccatin III to N-deacyldocetaxel, a precursor of the pharmaceutical docetaxel.	Docetaxel	80-89	myelin basic protein	Homo sapiens	0-3
28863941-7	2017	Our results show that metHb causes oxidative damage to MBP and myelin lipids, partly by transferring its hemin moiety to protein and lipid, but mostly as an intact protein possibly via formation of a ferryl radical.	Hemin	105-110	myelin basic protein	Homo sapiens	55-58
28757211-5	2017	By solving crystal structures of maltose binding protein (MBP)-fused AID alone and in complex with deoxycytidine monophosphate, we surprisingly identify a bifurcated substrate-binding surface that explains structured substrate recognition by capturing two adjacent single-stranded overhangs simultaneously.	Deoxycytidine Monophosphate	99-126	myelin basic protein	Homo sapiens	33-56
28656478-9	2017	Levels of anti-MBP were negatively associated with delayed verbal recall (DVR; r = -0.42, p = 0.005), Stroop Color-Word (r = -0.48, p = 0.004), and N-Back Total scores (r = -0.59, p &lt; 0.0001) and positively with Trail Making Test B (TMB, r = 0.53, p = 0.001).	1,2,4,5-tetramethoxybenzene	236-239	myelin basic protein	Homo sapiens	15-18
28648598-0	2017	Myelin basic protein stimulates plasminogen activation via tissue plasminogen activator following binding to independent l-lysine-containing domains.	Lysine	121-129	myelin basic protein	Homo sapiens	0-20
28648598-4	2017	This mechanism involves the binding of t-PA via a lysine-dependent mechanism to the Lys91 residue of the MBP NH2-terminal region Asp82 -Pro99, and the binding of Pg via a lysine-dependent mechanism to the Lys122 residue of the MBP COOH-terminal region Leu109-Gly126.	Lysine	50-56	myelin basic protein	Homo sapiens	105-108
28707358-8	2017	DHEA-S treatment also preserved myelin basic protein immunoreactivity and reduced axonal loss in animals with EAE, relative to vehicle-treated EAE animals.	Dehydroepiandrosterone	0-6	myelin basic protein	Homo sapiens	32-52
28865468-8	2017	Several dementia-specific citrulline residues were also identified in soluble proteins previously categorized as pro-immunogenic, which include the receptor P2X7, alpha-internexin, GFAP, CNP, MBP, and histones.	Citrulline	26-36	myelin basic protein	Homo sapiens	192-195
28558119-8	2017	To confirm the conformational sampling efficiency, the extended SDS was applied to maltodextrin binding protein (MBP), and we successfully reproduced the structural transition from the open to closed states with submicrosecond-order simulation times.	sds	64-67	myelin basic protein	Homo sapiens	83-111
28558119-8	2017	To confirm the conformational sampling efficiency, the extended SDS was applied to maltodextrin binding protein (MBP), and we successfully reproduced the structural transition from the open to closed states with submicrosecond-order simulation times.	sds	64-67	myelin basic protein	Homo sapiens	113-116
28757211-5	2017	By solving crystal structures of maltose binding protein (MBP)-fused AID alone and in complex with deoxycytidine monophosphate, we surprisingly identify a bifurcated substrate-binding surface that explains structured substrate recognition by capturing two adjacent single-stranded overhangs simultaneously.	Deoxycytidine Monophosphate	99-126	myelin basic protein	Homo sapiens	58-61
27573615-5	2017	We demonstrate that myelin basic protein (MBP) is inhibitory to both pNSC and dNSC derived colony formation.	dansyl chloride	78-82	myelin basic protein	Homo sapiens	20-40
28380689-0	2017	Docking and molecular dynamics simulations of the Fyn-SH3 domain with free and phospholipid bilayer-associated 18.5-kDa myelin basic protein (MBP)-Insights into a noncanonical and fuzzy interaction.	Phospholipids	79-91	myelin basic protein	Homo sapiens	120-140
28380689-0	2017	Docking and molecular dynamics simulations of the Fyn-SH3 domain with free and phospholipid bilayer-associated 18.5-kDa myelin basic protein (MBP)-Insights into a noncanonical and fuzzy interaction.	Phospholipids	79-91	myelin basic protein	Homo sapiens	142-145
28380689-2	2017	The results show that interaction between the two proteins is energetically favorable and heavily dependent on the MBP proline-rich region (P93-P98) in both aqueous and membrane environments.	Proline	119-126	myelin basic protein	Homo sapiens	115-118
28380689-6	2017	This study thus provides a more-detailed glimpse into the context-dependent interaction dynamics and importance of the beta-sheets in Fyn-SH3 and proline-rich region of MBP.	Proline	146-153	myelin basic protein	Homo sapiens	169-172
28504119-4	2017	Moreover, low or high concentrations of ALA, but not LA, and different ratios of LA/ALA resulted in a significant increase in mRNA expression levels of Notch1, Hes1 and Ki-67, and the differentiation of eNSCs toward astrocytes (GFAP) and oligodendrocytes (MBP), but not neurons (beta-III Tubulin), with the highest increase being for LA/ALA ratio of 1:3, in comparison to controls.	alpha-Linolenic Acid	40-43	myelin basic protein	Homo sapiens	256-259
28504119-4	2017	Moreover, low or high concentrations of ALA, but not LA, and different ratios of LA/ALA resulted in a significant increase in mRNA expression levels of Notch1, Hes1 and Ki-67, and the differentiation of eNSCs toward astrocytes (GFAP) and oligodendrocytes (MBP), but not neurons (beta-III Tubulin), with the highest increase being for LA/ALA ratio of 1:3, in comparison to controls.	alpha-Linolenic Acid	84-87	myelin basic protein	Homo sapiens	256-259
28504119-4	2017	Moreover, low or high concentrations of ALA, but not LA, and different ratios of LA/ALA resulted in a significant increase in mRNA expression levels of Notch1, Hes1 and Ki-67, and the differentiation of eNSCs toward astrocytes (GFAP) and oligodendrocytes (MBP), but not neurons (beta-III Tubulin), with the highest increase being for LA/ALA ratio of 1:3, in comparison to controls.	alpha-Linolenic Acid	84-87	myelin basic protein	Homo sapiens	256-259
28569182-8	2017	RESULTS: A four-SNP signature consisting of rs80191572 (in UVRAG), rs28724893 (in HLA-DQB2), rs1789084 (in MBP), and rs139890339 (in ZAK(CDCA7)) was identified as significantly associated with Copaxone response.	Glatiramer Acetate	193-201	myelin basic protein	Homo sapiens	107-110
28170260-5	2017	As a demonstration, SDS was first applied to maltodextrin binding protein (MBP) in explicit water to reproduce structural transitions between the open and closed states of MBP.	sds	20-23	myelin basic protein	Homo sapiens	45-73
28170260-5	2017	As a demonstration, SDS was first applied to maltodextrin binding protein (MBP) in explicit water to reproduce structural transitions between the open and closed states of MBP.	sds	20-23	myelin basic protein	Homo sapiens	75-78
28170260-5	2017	As a demonstration, SDS was first applied to maltodextrin binding protein (MBP) in explicit water to reproduce structural transitions between the open and closed states of MBP.	sds	20-23	myelin basic protein	Homo sapiens	172-175
28170260-5	2017	As a demonstration, SDS was first applied to maltodextrin binding protein (MBP) in explicit water to reproduce structural transitions between the open and closed states of MBP.	Water	92-97	myelin basic protein	Homo sapiens	45-73
28170260-5	2017	As a demonstration, SDS was first applied to maltodextrin binding protein (MBP) in explicit water to reproduce structural transitions between the open and closed states of MBP.	Water	92-97	myelin basic protein	Homo sapiens	75-78
28170260-6	2017	Structural transitions of MBP were successfully reproduced with SDS in nanosecond-order simulation times.	sds	64-67	myelin basic protein	Homo sapiens	26-29
27573615-5	2017	We demonstrate that myelin basic protein (MBP) is inhibitory to both pNSC and dNSC derived colony formation.	dansyl chloride	78-82	myelin basic protein	Homo sapiens	42-45
27750096-0	2017	Computational insights into the molecular interactions of environmental xenoestrogens 4-tert-octylphenol, 4-nonylphenol, bisphenol A (BPA), and BPA metabolite, 4-methyl-2, 4-bis (4-hydroxyphenyl) pent-1-ene (MBP) with human sex hormone-binding globulin.	bisphenol A	144-147	myelin basic protein	Homo sapiens	208-211
28174686-5	2017	When cleaved from MBP, hPAH-RD forms aggregates which are stereospecifically inhibited by l-Phe (&gt; 95%) at low physiological concentrations.	Phenylalanine	90-95	myelin basic protein	Homo sapiens	18-21
27750096-0	2017	Computational insights into the molecular interactions of environmental xenoestrogens 4-tert-octylphenol, 4-nonylphenol, bisphenol A (BPA), and BPA metabolite, 4-methyl-2, 4-bis (4-hydroxyphenyl) pent-1-ene (MBP) with human sex hormone-binding globulin.	4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene	160-206	myelin basic protein	Homo sapiens	208-211
27750096-6	2017	Bisphenol A is metabolized in the human body to a more potent compound (MBP: 4-Methyl-2, 4-bis (4-hydroxyphenyl) pent-1-ene).	bisphenol A	0-11	myelin basic protein	Homo sapiens	72-75
27750096-6	2017	Bisphenol A is metabolized in the human body to a more potent compound (MBP: 4-Methyl-2, 4-bis (4-hydroxyphenyl) pent-1-ene).	4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene	77-123	myelin basic protein	Homo sapiens	72-75
28250593-3	2017	Total base pair read was 1.1 Mbp in case of Dendrobium sp., 553.3 Kbp for Geodorum sp., 1.6 Gbp for Cymbidium, and 1.4 Gbp for Rhynchostylis.	dendrobium sp	44-57	myelin basic protein	Homo sapiens	29-32
27385127-6	2017	Using the selective site-1 protease (S1P) inhibitor PF-429242, which inhibits the cleavage of SREBP precursor forms into mature forms, we found that preventing SREBP processing inhibited process growth and reduced the expression level of myelin basic protein, a major component of myelin.	PF-429242	52-61	myelin basic protein	Homo sapiens	238-258
27730557-2	2017	MBP allows the use of a simple capture affinity step on Amylose-Agarose or Dextrin-Sepharose columns, resulting in a protein that is often 70-90 % pure in a single step.	Amylose	56-63	myelin basic protein	Homo sapiens	0-3
27730557-2	2017	MBP allows the use of a simple capture affinity step on Amylose-Agarose or Dextrin-Sepharose columns, resulting in a protein that is often 70-90 % pure in a single step.	Sepharose	64-71	myelin basic protein	Homo sapiens	0-3
27730557-2	2017	MBP allows the use of a simple capture affinity step on Amylose-Agarose or Dextrin-Sepharose columns, resulting in a protein that is often 70-90 % pure in a single step.	Dextrins	75-82	myelin basic protein	Homo sapiens	0-3
27730557-2	2017	MBP allows the use of a simple capture affinity step on Amylose-Agarose or Dextrin-Sepharose columns, resulting in a protein that is often 70-90 % pure in a single step.	Sepharose	83-92	myelin basic protein	Homo sapiens	0-3
27782255-6	2016	The activity of one MLCh (NGTA1-Me-pro) was inhibited only by EDTA, and it efficiently hydrolyzed MBP (but not other proteins) and four different oligopeptides corresponding to four known immunodominant sequences containing cleavage sites of MBP only in the presence of several different metal ions.	ngta1-me-pro	26-38	myelin basic protein	Homo sapiens	98-101
28745655-4	2017	In 46.3% of HTG patients and 38.7% of NTG patients, anti-MBP antibodies were lower than in the controls.	Nitroglycerin	38-41	myelin basic protein	Homo sapiens	57-60
28745655-8	2017	In this aspect, an increase in anti-MBP antibody production at the stage of early hydrodynamic disturbances (NTG) and its decrease at the stage of pronounced changes (HTG) are perfectly natural.	Nitroglycerin	109-112	myelin basic protein	Homo sapiens	36-39
27513556-5	2016	We found that proOLs responded to lipopolysaccharide (LPS)-stimulated microglia conditioned medium (L+M) by preserving toll-like receptor 4 (TLR4) expression, improving cell viability, and enhancing the expression of a myelinating OL marker myelin basic protein (MBP), compared to other OL lineage cells exposed to either LPS-stimulated (L+M) or nonstimulated microglia conditioned medium (LM).	prools	14-20	myelin basic protein	Homo sapiens	241-261
27513556-5	2016	We found that proOLs responded to lipopolysaccharide (LPS)-stimulated microglia conditioned medium (L+M) by preserving toll-like receptor 4 (TLR4) expression, improving cell viability, and enhancing the expression of a myelinating OL marker myelin basic protein (MBP), compared to other OL lineage cells exposed to either LPS-stimulated (L+M) or nonstimulated microglia conditioned medium (LM).	prools	14-20	myelin basic protein	Homo sapiens	263-266
27662851-6	2016	Compared with the control groups on week 2, 4 and 6, in CCPA-treated groups, the ratio of P-mTOR/mTOR, expression of MBP and IL-10 increased markedly, while the expression of TNF-alpha reduced at week 6.	2-chloro-N(6)cyclopentyladenosine	56-60	myelin basic protein	Homo sapiens	117-120
27697644-6	2016	A subset of these compounds, such as curcumin and resveratrol, affect multiple epigenetic processes, including DNMT inhibition, HDAC inactivation, MBP suppression, HAT activation, and microRNA modulation.	Curcumin	37-45	myelin basic protein	Homo sapiens	147-150
27697644-6	2016	A subset of these compounds, such as curcumin and resveratrol, affect multiple epigenetic processes, including DNMT inhibition, HDAC inactivation, MBP suppression, HAT activation, and microRNA modulation.	Resveratrol	50-61	myelin basic protein	Homo sapiens	147-150
27782255-6	2016	The activity of one MLCh (NGTA1-Me-pro) was inhibited only by EDTA, and it efficiently hydrolyzed MBP (but not other proteins) and four different oligopeptides corresponding to four known immunodominant sequences containing cleavage sites of MBP only in the presence of several different metal ions.	ngta1-me-pro	26-38	myelin basic protein	Homo sapiens	242-245
27782255-6	2016	The activity of one MLCh (NGTA1-Me-pro) was inhibited only by EDTA, and it efficiently hydrolyzed MBP (but not other proteins) and four different oligopeptides corresponding to four known immunodominant sequences containing cleavage sites of MBP only in the presence of several different metal ions.	Metals	288-293	myelin basic protein	Homo sapiens	98-101
27782255-7	2016	An unexpected result was obtained: NGTA1-Me-pro demonstrated two pH optima, two optimal concentrations of Me2+ ions, and two Km values for MBP.	ngta1-me-pro	35-47	myelin basic protein	Homo sapiens	139-142
27754697-2	2016	This study is aimed to determine the impact of the MBP hematopoietic PBX-interaction protein (HPIP) on breast cancer cell sensitivity to paclitaxel.	Paclitaxel	137-147	myelin basic protein	Homo sapiens	51-54
27752051-6	2016	Interestingly, T cells from fingolimod-treated patients exhibited interferon-gamma biased production, and more myelin basic protein-reactive cells was noted in CD56+ than in CD56- T cells.	Fingolimod Hydrochloride	28-38	myelin basic protein	Homo sapiens	111-131
27387237-5	2016	For the mutant, the induced amount of prodigiosin was drastically reduced to approximately 4% with the addition of 18 muM MBP-SpnR to the liquid medium, indicating 81% trapping of C6HSL.	c6hsl	180-185	myelin basic protein	Homo sapiens	122-125
27611715-4	2016	Our results showed that in the patient"s group the percentage of CD4(+)IL-4(+) cells was significantly increased in the presence of all concentrations of NaB when PBMCs were stimulated by MBP (p = 0.001) or PHA (p &lt; 0.03).	nab	154-157	myelin basic protein	Homo sapiens	188-191
27313511-4	2016	These cells exposed 1-4 days to low levels of H2O2 or to the protein kinase C (PKC) activator, phorbol-12-Myristate-13-Acetate (PMA) increased the expression of specific OL differentiation markers: the specific nuclear factor Olig-2, and Myelin Basic Protein (MBP), which was processed and accumulated selectively in membranes.	Hydrogen Peroxide	46-50	myelin basic protein	Homo sapiens	238-258
27097548-2	2016	Citrullination or deimination, a post-translational modification of protein-bound arginine into citrulline, catalyzed by Ca(2+) dependent peptidylarginine deiminase enzyme (PAD), plays an essential role in physiological processes include gene expression regulation, apoptosis and the plasticity of the central nervous system, while aberrant citrullination can generate new epitopes, thus involving in the initiation and/or progression of autoimmune disorder like MS. Myelin basic protein (MBP) is the major myelin protein and is generally considered to maintain the stability of the myelin sheath.	Arginine	82-90	myelin basic protein	Homo sapiens	467-487
27097548-2	2016	Citrullination or deimination, a post-translational modification of protein-bound arginine into citrulline, catalyzed by Ca(2+) dependent peptidylarginine deiminase enzyme (PAD), plays an essential role in physiological processes include gene expression regulation, apoptosis and the plasticity of the central nervous system, while aberrant citrullination can generate new epitopes, thus involving in the initiation and/or progression of autoimmune disorder like MS. Myelin basic protein (MBP) is the major myelin protein and is generally considered to maintain the stability of the myelin sheath.	Arginine	82-90	myelin basic protein	Homo sapiens	489-492
27097548-2	2016	Citrullination or deimination, a post-translational modification of protein-bound arginine into citrulline, catalyzed by Ca(2+) dependent peptidylarginine deiminase enzyme (PAD), plays an essential role in physiological processes include gene expression regulation, apoptosis and the plasticity of the central nervous system, while aberrant citrullination can generate new epitopes, thus involving in the initiation and/or progression of autoimmune disorder like MS. Myelin basic protein (MBP) is the major myelin protein and is generally considered to maintain the stability of the myelin sheath.	Citrulline	96-106	myelin basic protein	Homo sapiens	467-487
27097548-2	2016	Citrullination or deimination, a post-translational modification of protein-bound arginine into citrulline, catalyzed by Ca(2+) dependent peptidylarginine deiminase enzyme (PAD), plays an essential role in physiological processes include gene expression regulation, apoptosis and the plasticity of the central nervous system, while aberrant citrullination can generate new epitopes, thus involving in the initiation and/or progression of autoimmune disorder like MS. Myelin basic protein (MBP) is the major myelin protein and is generally considered to maintain the stability of the myelin sheath.	Citrulline	96-106	myelin basic protein	Homo sapiens	489-492
27387237-4	2016	Prodigiosin production was effectively inhibited by externally added MBP-SpnR in both wild-type AS-1 and the AHL synthase-defective mutant AS-1(DeltaspnI).	Prodigiosin	0-11	myelin basic protein	Homo sapiens	69-72
27519525-0	2016	Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset?	Isoaspartic Acid	0-16	myelin basic protein	Homo sapiens	49-69
27519525-5	2016	A common modification of MBP was racemization of Asp and this was significantly greater in MS patients.	Aspartic Acid	49-52	myelin basic protein	Homo sapiens	25-28
27519525-6	2016	In long-lived proteins, L-Asp and L-Asn can racemize to three other isomers, D-isoAsp, L-isoAsp and D-Asp and this is significant because isoAsp formation in peptides renders them immunogenic.Proteomic analysis revealed widespread modifications of MBP with two surface regions that are altered in MS.	Aspartic Acid	24-29	myelin basic protein	Homo sapiens	248-251
27519525-6	2016	In long-lived proteins, L-Asp and L-Asn can racemize to three other isomers, D-isoAsp, L-isoAsp and D-Asp and this is significant because isoAsp formation in peptides renders them immunogenic.Proteomic analysis revealed widespread modifications of MBP with two surface regions that are altered in MS.	Asparagine	34-39	myelin basic protein	Homo sapiens	248-251
27086975-7	2016	We also show that the lipid peroxidation product 4-hydroxynonenal co-localises with myelin and its levels negatively correlate to myelin basic protein levels.	4-hydroxy-2-nonenal	49-65	myelin basic protein	Homo sapiens	130-150
27313511-4	2016	These cells exposed 1-4 days to low levels of H2O2 or to the protein kinase C (PKC) activator, phorbol-12-Myristate-13-Acetate (PMA) increased the expression of specific OL differentiation markers: the specific nuclear factor Olig-2, and Myelin Basic Protein (MBP), which was processed and accumulated selectively in membranes.	Hydrogen Peroxide	46-50	myelin basic protein	Homo sapiens	260-263
27313511-4	2016	These cells exposed 1-4 days to low levels of H2O2 or to the protein kinase C (PKC) activator, phorbol-12-Myristate-13-Acetate (PMA) increased the expression of specific OL differentiation markers: the specific nuclear factor Olig-2, and Myelin Basic Protein (MBP), which was processed and accumulated selectively in membranes.	Tetradecanoylphorbol Acetate	95-126	myelin basic protein	Homo sapiens	238-258
27313511-4	2016	These cells exposed 1-4 days to low levels of H2O2 or to the protein kinase C (PKC) activator, phorbol-12-Myristate-13-Acetate (PMA) increased the expression of specific OL differentiation markers: the specific nuclear factor Olig-2, and Myelin Basic Protein (MBP), which was processed and accumulated selectively in membranes.	Tetradecanoylphorbol Acetate	95-126	myelin basic protein	Homo sapiens	260-263
27313511-4	2016	These cells exposed 1-4 days to low levels of H2O2 or to the protein kinase C (PKC) activator, phorbol-12-Myristate-13-Acetate (PMA) increased the expression of specific OL differentiation markers: the specific nuclear factor Olig-2, and Myelin Basic Protein (MBP), which was processed and accumulated selectively in membranes.	Tetradecanoylphorbol Acetate	128-131	myelin basic protein	Homo sapiens	238-258
27313511-4	2016	These cells exposed 1-4 days to low levels of H2O2 or to the protein kinase C (PKC) activator, phorbol-12-Myristate-13-Acetate (PMA) increased the expression of specific OL differentiation markers: the specific nuclear factor Olig-2, and Myelin Basic Protein (MBP), which was processed and accumulated selectively in membranes.	Tetradecanoylphorbol Acetate	128-131	myelin basic protein	Homo sapiens	260-263
26686919-2	2016	The thiolated ferrocene (Fc)-modified BPA-binding aptamer probe (Fc-P) was immobilized on the gold electrode and then hybridized with the methylene blue (MB)-modified complementary DNA probe (MB-P) to form a rigid double-stranded DNA (ds-DNA).	ferrocene	14-23	myelin basic protein	Homo sapiens	192-196
26304106-7	2016	Preoperative MBP with polyethylene glycol solution was used routinely between April 1992 and December 2004, and then it was abandoned.	Polyethylene Glycols	22-41	myelin basic protein	Homo sapiens	13-16
26686919-2	2016	The thiolated ferrocene (Fc)-modified BPA-binding aptamer probe (Fc-P) was immobilized on the gold electrode and then hybridized with the methylene blue (MB)-modified complementary DNA probe (MB-P) to form a rigid double-stranded DNA (ds-DNA).	ferrocene	25-27	myelin basic protein	Homo sapiens	192-196
26686919-2	2016	The thiolated ferrocene (Fc)-modified BPA-binding aptamer probe (Fc-P) was immobilized on the gold electrode and then hybridized with the methylene blue (MB)-modified complementary DNA probe (MB-P) to form a rigid double-stranded DNA (ds-DNA).	bisphenol A	38-41	myelin basic protein	Homo sapiens	192-196
26686919-3	2016	The specific interaction between BPA and Fc-P led to the release of MB-P from the sensing interface and the conformational change of Fc-P.	bisphenol A	33-36	myelin basic protein	Homo sapiens	68-72
26686919-3	2016	The specific interaction between BPA and Fc-P led to the release of MB-P from the sensing interface and the conformational change of Fc-P.	FC-P	41-45	myelin basic protein	Homo sapiens	68-72
26686919-3	2016	The specific interaction between BPA and Fc-P led to the release of MB-P from the sensing interface and the conformational change of Fc-P.	FC-P	133-137	myelin basic protein	Homo sapiens	68-72
26965011-6	2016	It has been found that benzophenone-2 (BP-2), BP-3, 4-methylbenzophenone (4-MBP) and OMC present in the culture medium for 72h in high concentration (10(-5) and 10(-4)M) and 4-MBC only 10(-4)M produced a significant cytotoxic effect, as determined both by the MTT reduction test and LDH release assay.	benzophenone	23-35	myelin basic protein	Homo sapiens	76-79
26953870-13	2016	Mean (SD) number of myelin basic protein peptide-specific cells secreting interferon gamma and interleukin (IL)-17 were significantly reduced in patients receiving metformin compared with controls (interferon gamma, 30.3 [11.5] vs 82.8 [18.8], P &lt; .001; IL-17, 212.4 [85.5] vs 553.8 [125.9], P &lt; .001).	Metformin	164-173	myelin basic protein	Homo sapiens	20-40
26953870-14	2016	Patients treated with pioglitazone showed significant decreases in the mean (SD) number of myelin basic protein peptide-specific cells secreting IL-6 and tumor necrosis factor compared with controls (IL-6, 361.6 [80.5] vs 1130.7 [149.21], P &lt; .001; tumor necrosis factor, 189.9 [53.4] vs 341.0 [106.0], P &lt; .001).	Pioglitazone	22-34	myelin basic protein	Homo sapiens	91-111
27003577-3	2016	The fusion proteins were purified by Ni-NTA chromatography, MBP-VP2 showed the highest purity about 90 %.	ni-nta	37-43	myelin basic protein	Homo sapiens	60-63
26965011-6	2016	It has been found that benzophenone-2 (BP-2), BP-3, 4-methylbenzophenone (4-MBP) and OMC present in the culture medium for 72h in high concentration (10(-5) and 10(-4)M) and 4-MBC only 10(-4)M produced a significant cytotoxic effect, as determined both by the MTT reduction test and LDH release assay.	bp-3, 4-methylbenzophenone	46-72	myelin basic protein	Homo sapiens	76-79
26683986-10	2016	Through the evaluation of the hemodynamic parameters that were measured by the 24-hr ambulatory monitoring, we observed that SBP, MBP, and the percentage of time with SBP over the normal were significantly reduced only after the LTP treatment (P &lt; 0.05).	4-Amino-1-{2-Deoxy-5-O-[(R)-Hydroxy(Phosphonooxy)phosphoryl]-Beta-L-Erythro-Pentofuranosyl}pyrimidin-2(1h)-One	229-232	myelin basic protein	Homo sapiens	130-133
26781085-9	2016	The ability of hydrocortisone to inhibit IL-17 and IL-22 production by MBP-specific CD4(+) T cells was inversely related to the number of active brain lesions.	Hydrocortisone	15-29	myelin basic protein	Homo sapiens	71-74
26973830-4	2016	Both techniques were proved to be very useful tools for monitoring all the functionalization steps, including the investigation of the biological behavior of the glucose-modified particles in the presence of the maltose binding protein.	Glucose	162-169	myelin basic protein	Homo sapiens	212-235
26821943-1	2016	We report ab initio time-domain simulations of nonradiative electron-hole recombination and electronic dephasing in ideal and defect-containing monolayer black phosphorus (MBP).	Phosphorus	154-170	myelin basic protein	Homo sapiens	172-175
26821943-2	2016	Our calculations predict that the presence of phosphorus divacancy in MBP (MBP-DV) substantially reduces the nonradiative recombination rate, with time scales on the order of 1.57 ns.	Phosphorus	46-56	myelin basic protein	Homo sapiens	70-73
26821943-2	2016	Our calculations predict that the presence of phosphorus divacancy in MBP (MBP-DV) substantially reduces the nonradiative recombination rate, with time scales on the order of 1.57 ns.	Phosphorus	46-56	myelin basic protein	Homo sapiens	75-81
26983404-4	2016	Functional proteomic analysis of AD + CVD brain tissues revealed increased citrullination of arginine and deamidation of glutamine residues of myelin basic protein (MBP) in female which impaired degradation of degenerated MBP and resulted in accumulation of non-functional MBP in WM.	Glutamine	121-130	myelin basic protein	Homo sapiens	143-163
26983404-4	2016	Functional proteomic analysis of AD + CVD brain tissues revealed increased citrullination of arginine and deamidation of glutamine residues of myelin basic protein (MBP) in female which impaired degradation of degenerated MBP and resulted in accumulation of non-functional MBP in WM.	Glutamine	121-130	myelin basic protein	Homo sapiens	165-168
26983404-4	2016	Functional proteomic analysis of AD + CVD brain tissues revealed increased citrullination of arginine and deamidation of glutamine residues of myelin basic protein (MBP) in female which impaired degradation of degenerated MBP and resulted in accumulation of non-functional MBP in WM.	Glutamine	121-130	myelin basic protein	Homo sapiens	222-225
26707622-11	2016	Immunoblotting indicated that maltose-binding protein (MBP)-OGT inhibited the binding of His-p120 to GST-ECD in a dose-dependent manner.	Histidine	89-92	myelin basic protein	Homo sapiens	30-53
26707622-11	2016	Immunoblotting indicated that maltose-binding protein (MBP)-OGT inhibited the binding of His-p120 to GST-ECD in a dose-dependent manner.	Histidine	89-92	myelin basic protein	Homo sapiens	55-58
27463335-7	2016	We purified IFNalpha-2b from the MBP-tagged fusion using immobilized metal affinity chromatography and anion exchange chromatography, and obtained a final yield of 7.2 mg from an initial 500-ml culture.	Metals	69-74	myelin basic protein	Homo sapiens	33-36
27019682-2	2016	MBP is involved in maltose transport and bacterial chemotaxis; it binds to maltose and maltodextrins comprising alpha(1-4)-glucosidically linked linear glucose polymers and alpha(1-4)-glucosidically linked cyclodextrins.	Maltose	19-26	myelin basic protein	Homo sapiens	0-3
27019682-2	2016	MBP is involved in maltose transport and bacterial chemotaxis; it binds to maltose and maltodextrins comprising alpha(1-4)-glucosidically linked linear glucose polymers and alpha(1-4)-glucosidically linked cyclodextrins.	Maltose	75-82	myelin basic protein	Homo sapiens	0-3
27019682-2	2016	MBP is involved in maltose transport and bacterial chemotaxis; it binds to maltose and maltodextrins comprising alpha(1-4)-glucosidically linked linear glucose polymers and alpha(1-4)-glucosidically linked cyclodextrins.	maltodextrin	87-100	myelin basic protein	Homo sapiens	0-3
27019682-2	2016	MBP is involved in maltose transport and bacterial chemotaxis; it binds to maltose and maltodextrins comprising alpha(1-4)-glucosidically linked linear glucose polymers and alpha(1-4)-glucosidically linked cyclodextrins.	Glucans	152-168	myelin basic protein	Homo sapiens	0-3
27019682-2	2016	MBP is involved in maltose transport and bacterial chemotaxis; it binds to maltose and maltodextrins comprising alpha(1-4)-glucosidically linked linear glucose polymers and alpha(1-4)-glucosidically linked cyclodextrins.	Cyclodextrins	206-219	myelin basic protein	Homo sapiens	0-3
27019682-11	2016	Our mutant MBP retains maltose-binding activity and is suitable for reagentless fluorescence sensing.	Maltose	23-30	myelin basic protein	Homo sapiens	11-14
26659261-3	2016	The enzymes methylating CpG dinucleotides and those involved in the active demethylation of 5-metylcytosine (5mC) are outlined together with the members of the methyl binding protein (MBP) family that bind to and "interpret" the 5mC mark.	Dinucleoside Phosphates	28-41	myelin basic protein	Homo sapiens	160-182
26659261-3	2016	The enzymes methylating CpG dinucleotides and those involved in the active demethylation of 5-metylcytosine (5mC) are outlined together with the members of the methyl binding protein (MBP) family that bind to and "interpret" the 5mC mark.	Dinucleoside Phosphates	28-41	myelin basic protein	Homo sapiens	184-187
26659261-3	2016	The enzymes methylating CpG dinucleotides and those involved in the active demethylation of 5-metylcytosine (5mC) are outlined together with the members of the methyl binding protein (MBP) family that bind to and "interpret" the 5mC mark.	5-metylcytosine	92-107	myelin basic protein	Homo sapiens	160-182
26659261-3	2016	The enzymes methylating CpG dinucleotides and those involved in the active demethylation of 5-metylcytosine (5mC) are outlined together with the members of the methyl binding protein (MBP) family that bind to and "interpret" the 5mC mark.	5-metylcytosine	92-107	myelin basic protein	Homo sapiens	184-187
26659261-3	2016	The enzymes methylating CpG dinucleotides and those involved in the active demethylation of 5-metylcytosine (5mC) are outlined together with the members of the methyl binding protein (MBP) family that bind to and "interpret" the 5mC mark.	5-Methylcytidine 5'-monophosphate	109-112	myelin basic protein	Homo sapiens	160-182
26659261-3	2016	The enzymes methylating CpG dinucleotides and those involved in the active demethylation of 5-metylcytosine (5mC) are outlined together with the members of the methyl binding protein (MBP) family that bind to and "interpret" the 5mC mark.	5-Methylcytidine 5'-monophosphate	109-112	myelin basic protein	Homo sapiens	184-187
26659261-3	2016	The enzymes methylating CpG dinucleotides and those involved in the active demethylation of 5-metylcytosine (5mC) are outlined together with the members of the methyl binding protein (MBP) family that bind to and "interpret" the 5mC mark.	5-Methylcytidine 5'-monophosphate	229-232	myelin basic protein	Homo sapiens	160-182
26659261-3	2016	The enzymes methylating CpG dinucleotides and those involved in the active demethylation of 5-metylcytosine (5mC) are outlined together with the members of the methyl binding protein (MBP) family that bind to and "interpret" the 5mC mark.	5-Methylcytidine 5'-monophosphate	229-232	myelin basic protein	Homo sapiens	184-187
26180512-9	2015	MBP values in the etomidate group decreased significantly less than those in the propofol group (P&lt;0.05).	Etomidate	18-27	myelin basic protein	Homo sapiens	0-3
26315944-4	2015	Transcripts for essential myelin-associated genes, such as PLP, MAG, MBP, CNPase, and MOG, in addition to transcription factors that regulate oligodendrocyte differentiation and myelination, were rapidly increased after treatment with donepezil.	Donepezil	235-244	myelin basic protein	Homo sapiens	69-72
26315944-5	2015	Furthermore, luciferase assays confirmed that both MAG and MBP promoters display increased activity upon donepezil-induced oligodendrocytes differentiation, suggesting that donepezil increases myelin gene expression mainly through enhanced transcription.	Donepezil	105-114	myelin basic protein	Homo sapiens	59-62
26315944-5	2015	Furthermore, luciferase assays confirmed that both MAG and MBP promoters display increased activity upon donepezil-induced oligodendrocytes differentiation, suggesting that donepezil increases myelin gene expression mainly through enhanced transcription.	Donepezil	173-182	myelin basic protein	Homo sapiens	59-62
26315944-10	2015	Transcripts for essential myelin-associated genes, such as PLP, MAG, MBP, CNPase and MOG in addition to transcripton factors that regulate oligodendrocyte differentiation and myelination were rapidly increased after treatment with donepezil.	Donepezil	231-240	myelin basic protein	Homo sapiens	69-72
26518750-0	2015	MyelStones: the executive roles of myelin basic protein in myelin assembly and destabilization in multiple sclerosis.	myelstones	0-10	myelin basic protein	Homo sapiens	35-55
26287632-3	2015	We demonstrate our method by measuring the conformational changes that occur upon ligand binding with three well-characterized proteins labeled at lysine residues: calmodulin (CaM), maltose-binding protein (MBP), and dihydrofolate reductase (DHFR).	Lysine	147-153	myelin basic protein	Homo sapiens	207-210
26238238-4	2015	Axons releasing neurotransmitter from vesicles that accumulate in axon varicosities induces a local rise in cytoplasmic calcium in glial cell processes at these nonsynaptic functional junctions, and this signalling stimulates local translation of myelin basic protein to initiate myelination.	Calcium	120-127	myelin basic protein	Homo sapiens	247-267
25999342-5	2015	MBP-U94 is also able to hydrolyze adenosine triphosphate (ATP) to ADP, providing the energy for further catalytic activities.	Adenosine Triphosphate	34-56	myelin basic protein	Homo sapiens	0-3
25999342-5	2015	MBP-U94 is also able to hydrolyze adenosine triphosphate (ATP) to ADP, providing the energy for further catalytic activities.	Adenosine Triphosphate	58-61	myelin basic protein	Homo sapiens	0-3
26214776-11	2015	We also found olanzapine increased the protein expression of MBP and GFAP.	Olanzapine	14-24	myelin basic protein	Homo sapiens	61-64
26658258-8	2015	Further, RxRgamma activation is required for MBP expression upon Halcinonide and Clobetasol treatment.	Halcinonide	65-76	myelin basic protein	Homo sapiens	45-48
26658258-8	2015	Further, RxRgamma activation is required for MBP expression upon Halcinonide and Clobetasol treatment.	Clobetasol	81-91	myelin basic protein	Homo sapiens	45-48
26551210-3	2015	Our protein interaction studies revealed that a millimolar concentration of sodium diclofenac is able to elute glutathione S-transferase (GST), cellulose binding protein (CBD), and maltose binding protein (MBP) but not histidine-tagged or PDZ-tagged proteins from their affinity resins.	Diclofenac	76-93	myelin basic protein	Homo sapiens	181-204
26551210-3	2015	Our protein interaction studies revealed that a millimolar concentration of sodium diclofenac is able to elute glutathione S-transferase (GST), cellulose binding protein (CBD), and maltose binding protein (MBP) but not histidine-tagged or PDZ-tagged proteins from their affinity resins.	Diclofenac	76-93	myelin basic protein	Homo sapiens	206-209
26287169-5	2015	Also addition of KB-R7943, NCX3 inhibitor, to simulate Pb toxicity, resulted in decreased myelin basic protein (MBP) expression and cell branching.	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate	17-25	myelin basic protein	Homo sapiens	90-110
26287169-5	2015	Also addition of KB-R7943, NCX3 inhibitor, to simulate Pb toxicity, resulted in decreased myelin basic protein (MBP) expression and cell branching.	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate	17-25	myelin basic protein	Homo sapiens	112-115
26287169-5	2015	Also addition of KB-R7943, NCX3 inhibitor, to simulate Pb toxicity, resulted in decreased myelin basic protein (MBP) expression and cell branching.	Lead	55-57	myelin basic protein	Homo sapiens	90-110
26287169-5	2015	Also addition of KB-R7943, NCX3 inhibitor, to simulate Pb toxicity, resulted in decreased myelin basic protein (MBP) expression and cell branching.	Lead	55-57	myelin basic protein	Homo sapiens	112-115
26287169-7	2015	In contrast, over-expression of NCX3 in Pb exposed OPCs displayed significant increase MBP fluorescence signal in positive regions and CNPase expression, which recovered OPCs differentiation to counterbalance Pb toxicity.	Lead	40-42	myelin basic protein	Homo sapiens	87-90
26134749-6	2015	IL-1beta can activate eosinophils, which can release major basic protein (MBP) to antagonize the M2 receptors leading to excessive acetylcholine release.	Acetylcholine	131-144	myelin basic protein	Homo sapiens	74-77
25999342-5	2015	MBP-U94 is also able to hydrolyze adenosine triphosphate (ATP) to ADP, providing the energy for further catalytic activities.	Adenosine Diphosphate	66-69	myelin basic protein	Homo sapiens	0-3
25906331-1	2015	Glatiramer acetate (Copaxone( )) is a synthetic analogue of myelin basic protein, which is thought to be involved in the pathogenesis of multiple sclerosis (MS).	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	60-80
25969923-4	2015	ALP is simply conjugated to a ZFP through lysine residues in a ZFP purification tag, a maltose binding protein (MBP).	Lysine	42-48	myelin basic protein	Homo sapiens	87-110
25969923-4	2015	ALP is simply conjugated to a ZFP through lysine residues in a ZFP purification tag, a maltose binding protein (MBP).	Lysine	42-48	myelin basic protein	Homo sapiens	112-115
26132787-0	2015	Correction: The Effects of Threonine Phosphorylation on the Stability and Dynamics of the Central Molecular Switch Region of 18.5-kDa Myelin Basic Protein.	Threonine	27-36	myelin basic protein	Homo sapiens	134-154
32262393-5	2015	The three functional domains of (MBP)-BSP-HAP provide the artificial protein with multiple designated functions for intrafibrillar mineralization including binding calcium ions, binding collagen, and binding hydroxyapatite.	Calcium	164-171	myelin basic protein	Homo sapiens	33-36
32262393-6	2015	Platelet-like hydroxyapatite crystals periodically arranged inside the collagen fibrils have been achieved under the function of (MBP)-BSP-HAP.	Durapatite	14-28	myelin basic protein	Homo sapiens	130-133
25906331-1	2015	Glatiramer acetate (Copaxone( )) is a synthetic analogue of myelin basic protein, which is thought to be involved in the pathogenesis of multiple sclerosis (MS).	Glatiramer Acetate	20-28	myelin basic protein	Homo sapiens	60-80
25576930-3	2015	The aim of this study was to detect the level of autoantibodies and lympho-proliferative response against myelin basic protein (MBP) in leprosy patients (LPs) and their correlation with clinical phenotypes of LPs.	lps	154-157	myelin basic protein	Homo sapiens	106-126
25366938-8	2015	Further, the decrease of myelin basic protein, myelin loss, and axon loss in white matter was also significantly blocked by fluoxetine, as compared to vehicle control.	Fluoxetine	124-134	myelin basic protein	Homo sapiens	25-45
26178214-9	2015	However, the expression of MBP protein decreased more significantly in saline control group, while the level of the MAG protein expression increased.	Sodium Chloride	71-77	myelin basic protein	Homo sapiens	27-30
25576930-3	2015	The aim of this study was to detect the level of autoantibodies and lympho-proliferative response against myelin basic protein (MBP) in leprosy patients (LPs) and their correlation with clinical phenotypes of LPs.	lps	154-157	myelin basic protein	Homo sapiens	128-131
25576930-3	2015	The aim of this study was to detect the level of autoantibodies and lympho-proliferative response against myelin basic protein (MBP) in leprosy patients (LPs) and their correlation with clinical phenotypes of LPs.	lps	209-212	myelin basic protein	Homo sapiens	106-126
25576930-3	2015	The aim of this study was to detect the level of autoantibodies and lympho-proliferative response against myelin basic protein (MBP) in leprosy patients (LPs) and their correlation with clinical phenotypes of LPs.	lps	209-212	myelin basic protein	Homo sapiens	128-131
25576930-5	2015	We observed significantly high level of anti-MBP antibodies in LPs across the spectrum and a positive significant correlation between the level of anti-MBP antibodies and the number of nerves involved in LPs.	lps	63-66	myelin basic protein	Homo sapiens	45-48
25576930-5	2015	We observed significantly high level of anti-MBP antibodies in LPs across the spectrum and a positive significant correlation between the level of anti-MBP antibodies and the number of nerves involved in LPs.	lps	204-207	myelin basic protein	Homo sapiens	152-155
25773150-9	2015	Autistic patients with increased serum levels of anti-MBP auto-antibodies (75%) had significantly lower plasma DHA (P&lt;0.5) and significantly higher omega6/omega3 ratio (P&lt;0.5) than patients who were seronegative for these antibodies.	dehydroacetic acid	111-114	myelin basic protein	Homo sapiens	54-57
25706854-10	2015	The saturated surface concentration of compact MBP on a single SiO2 surface reaches a stable value of 310 +- 10 ng/cm(2) regardless of the bulk MBP concentration.	Silicon Dioxide	63-67	myelin basic protein	Homo sapiens	47-50
25585037-9	2015	Bumetanide treatment significantly attenuates myelin basic protein loss and neuronal degeneration 7 d post-HI.	Bumetanide	0-10	myelin basic protein	Homo sapiens	46-66
25773150-10	2015	In conclusions, some autistic children have a significant positive association between reduced levels of plasma DHA and increased serum levels of anti-MBP brain-specific auto-antibodies.	dehydroacetic acid	112-115	myelin basic protein	Homo sapiens	151-154
25613453-4	2015	We identified 17 005 directly oriented LINE pairs located &lt;10 Mbp from each other as potential NAHR substrates, placing 82.8% of the human genome at risk of LINE-LINE-mediated instability.	nahr	98-102	myelin basic protein	Homo sapiens	65-68
25650239-3	2015	Using alanine-scanning mutagenesis simulations, we identified two scaffold residues that are critical to the binding interaction between the monobody YS1 and its ligand, maltose-binding protein (MBP).	Alanine	6-13	myelin basic protein	Homo sapiens	170-193
25705874-3	2015	In axon-related SCs, cAMP induced the expression of Krox-20 and O1 without a concomitant increase in the expression of myelin basic protein (MBP) and without promoting axon ensheathment, collagen synthesis or basal lamina assembly.	Cyclic AMP	21-25	myelin basic protein	Homo sapiens	119-139
25705874-3	2015	In axon-related SCs, cAMP induced the expression of Krox-20 and O1 without a concomitant increase in the expression of myelin basic protein (MBP) and without promoting axon ensheathment, collagen synthesis or basal lamina assembly.	Cyclic AMP	21-25	myelin basic protein	Homo sapiens	141-144
25705874-4	2015	When cAMP was provided together with ascorbate, a dramatic enhancement of MBP expression occurred, indicating that cAMP primes SCs to form myelin only under conditions supportive of basal lamina formation.	Cyclic AMP	5-9	myelin basic protein	Homo sapiens	74-77
25705874-4	2015	When cAMP was provided together with ascorbate, a dramatic enhancement of MBP expression occurred, indicating that cAMP primes SCs to form myelin only under conditions supportive of basal lamina formation.	Ascorbic Acid	37-46	myelin basic protein	Homo sapiens	74-77
25705874-4	2015	When cAMP was provided together with ascorbate, a dramatic enhancement of MBP expression occurred, indicating that cAMP primes SCs to form myelin only under conditions supportive of basal lamina formation.	Cyclic AMP	115-119	myelin basic protein	Homo sapiens	74-77
25650239-3	2015	Using alanine-scanning mutagenesis simulations, we identified two scaffold residues that are critical to the binding interaction between the monobody YS1 and its ligand, maltose-binding protein (MBP).	Alanine	6-13	myelin basic protein	Homo sapiens	195-198
25650239-4	2015	Steered molecular dynamics (SMD) simulations predicted that the E47A and R33A mutations in the YS1 scaffold substantially destabilize the YS1-MBP interface by reducing the bond rupture force and the lifetime of single hydrogen bonds.	Hydrogen	218-226	myelin basic protein	Homo sapiens	142-145
25650239-5	2015	SMD simulations further indicated that the R33A mutation weakens the hydrogen binding between all scaffold residues and MBP and not just between R33 and MBP.	Hydrogen	69-77	myelin basic protein	Homo sapiens	120-123
25157906-6	2014	We observed that diazoxide increases the ratio of differentiated oligodendrocytes in the cerebral white matter, promotes the expression of differentiation-associated transcriptional factors Nkx2.2 and Sox10, and increases the expression of myelin genes CNP and MBP.	Diazoxide	17-26	myelin basic protein	Homo sapiens	261-264
25644378-0	2015	Homo-beta-amino acid containing MBP(85-99) analogs alleviate experimental autoimmune encephalomyelitis.	homo-beta-amino acid	0-20	myelin basic protein	Homo sapiens	32-35
24999995-1	2014	We have previously shown that a genetically encoded bioluminescent resonance energy transfer (BRET) biosensor, comprising maltose binding protein (MBP) flanked by a green fluorescent protein (GFP(2)) at the N-terminus and a variant of Renilla luciferase (RLuc2) at the C-terminus, has superior sensitivity and limits of detection for maltose, compared with an equivalent fluorescent resonance energy transfer (FRET) biosensor.	Maltose	122-129	myelin basic protein	Homo sapiens	147-150
24999995-2	2014	Here, we demonstrate that the same MBP biosensor can be combined with a microfluidic system for detection of maltose in water or beer.	Maltose	109-116	myelin basic protein	Homo sapiens	35-38
24999995-2	2014	Here, we demonstrate that the same MBP biosensor can be combined with a microfluidic system for detection of maltose in water or beer.	Water	120-125	myelin basic protein	Homo sapiens	35-38
25422949-2	2014	In this study, a maltose-binding protein (MBP)-linked basic fibroblast growth factor (FGF2)-immobilised polystyrene surface (PS-MBP-FGF2) was applied as an artificial matrix to regulate integrin-mediated signalling.	Polystyrenes	104-115	myelin basic protein	Homo sapiens	17-40
25422949-2	2014	In this study, a maltose-binding protein (MBP)-linked basic fibroblast growth factor (FGF2)-immobilised polystyrene surface (PS-MBP-FGF2) was applied as an artificial matrix to regulate integrin-mediated signalling.	Polystyrenes	104-115	myelin basic protein	Homo sapiens	42-45
25127400-0	2014	Use of cloneable peptide-MBP fusion protein as a mimetic coating antigen in the standardized immunoassay for mycotoxin ochratoxin A.	ochratoxin A	119-131	myelin basic protein	Homo sapiens	25-28
25034963-2	2014	Here we report on the imprinting of fluorescently-labeled maltose binding protein (MBP) in acrylamide (AAm)/N-isopropylacrylamide (NIPAm) hydrogels.	Acrylamide	91-101	myelin basic protein	Homo sapiens	58-81
25034963-2	2014	Here we report on the imprinting of fluorescently-labeled maltose binding protein (MBP) in acrylamide (AAm)/N-isopropylacrylamide (NIPAm) hydrogels.	Acrylamide	91-101	myelin basic protein	Homo sapiens	83-86
25034963-2	2014	Here we report on the imprinting of fluorescently-labeled maltose binding protein (MBP) in acrylamide (AAm)/N-isopropylacrylamide (NIPAm) hydrogels.	Acrylamide	103-106	myelin basic protein	Homo sapiens	58-81
25034963-2	2014	Here we report on the imprinting of fluorescently-labeled maltose binding protein (MBP) in acrylamide (AAm)/N-isopropylacrylamide (NIPAm) hydrogels.	Acrylamide	103-106	myelin basic protein	Homo sapiens	83-86
25034963-2	2014	Here we report on the imprinting of fluorescently-labeled maltose binding protein (MBP) in acrylamide (AAm)/N-isopropylacrylamide (NIPAm) hydrogels.	N-isopropylacrylamide	108-129	myelin basic protein	Homo sapiens	58-81
25034963-2	2014	Here we report on the imprinting of fluorescently-labeled maltose binding protein (MBP) in acrylamide (AAm)/N-isopropylacrylamide (NIPAm) hydrogels.	N-isopropylacrylamide	108-129	myelin basic protein	Homo sapiens	83-86
25034963-2	2014	Here we report on the imprinting of fluorescently-labeled maltose binding protein (MBP) in acrylamide (AAm)/N-isopropylacrylamide (NIPAm) hydrogels.	N-isopropylacrylamide	131-136	myelin basic protein	Homo sapiens	58-81
25034963-2	2014	Here we report on the imprinting of fluorescently-labeled maltose binding protein (MBP) in acrylamide (AAm)/N-isopropylacrylamide (NIPAm) hydrogels.	N-isopropylacrylamide	131-136	myelin basic protein	Homo sapiens	83-86
24865975-10	2014	These data suggest that phosphorylated exon 2-containing (21.5- and possibly 17-kDa) MBP isoforms may play critical roles in myelination and that hypothermia attenuates apoptosis and preserves the contact between OLs and neurons via ERK1/2 phosphorylation.	N-biotin-C-Co4(mu3-O)4(Py)4(H2O)4-beta-alanine	213-216	myelin basic protein	Homo sapiens	85-88
25003183-0	2014	The lateral membrane organization and dynamics of myelin proteins PLP and MBP are dictated by distinct galactolipids and the extracellular matrix.	Galactolipids	103-116	myelin basic protein	Homo sapiens	74-77
25170258-1	2014	Glatiramer acetate, a synthetic amino acid polymer analog of myelin basic protein, is one of the first approved drugs for the treatment of relapsing-remitting multiple sclerosis.	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	61-81
24945073-2	2014	As compared with well-known fusion tags such as glutathione-S-transferase (GST) and maltose-binding protein (MBP), the performance of CysQ as solubility enhancer was evidently better than GST and was similar to or better than MBP for the seven heterologous proteins above.	cysq	134-138	myelin basic protein	Homo sapiens	84-107
24945073-2	2014	As compared with well-known fusion tags such as glutathione-S-transferase (GST) and maltose-binding protein (MBP), the performance of CysQ as solubility enhancer was evidently better than GST and was similar to or better than MBP for the seven heterologous proteins above.	cysq	134-138	myelin basic protein	Homo sapiens	109-112
24945073-2	2014	As compared with well-known fusion tags such as glutathione-S-transferase (GST) and maltose-binding protein (MBP), the performance of CysQ as solubility enhancer was evidently better than GST and was similar to or better than MBP for the seven heterologous proteins above.	cysq	134-138	myelin basic protein	Homo sapiens	226-229
24907905-2	2014	Post-translational modification of central nervous system proteins, including glial fibrillary acidic protein (GFAP) and myelin basic protein (MBP), through citrullination of arginine residues, may lead to exposure of neoepitopes, triggering autoimmunity.	Arginine	175-183	myelin basic protein	Homo sapiens	121-141
24907905-2	2014	Post-translational modification of central nervous system proteins, including glial fibrillary acidic protein (GFAP) and myelin basic protein (MBP), through citrullination of arginine residues, may lead to exposure of neoepitopes, triggering autoimmunity.	Arginine	175-183	myelin basic protein	Homo sapiens	143-146
24571714-5	2014	RESULTS: Patients in clinical relapse and patients with nonsymptomatic gadolinium enhancing lesions had high levels of MBP and NFL, indicating ongoing damage to oligodendrocytes and axons.	Gadolinium	71-81	myelin basic protein	Homo sapiens	119-122
24837160-11	2014	The calcium carbonate precipitation assay shows that both MBP-AP7 and AP7 exhibit morphological modification on calcite crystallites.	Calcium Carbonate	4-21	myelin basic protein	Homo sapiens	58-61
24837160-12	2014	The co-precipitation of MBP-tagged AP7 derivatives and calcium carbonate generate different types of AP7 composite calcite and vaterite crystals.	Calcium Carbonate	127-135	myelin basic protein	Homo sapiens	24-27
24131788-0	2014	The high-affinity maltose switch MBP317-347 has low affinity for glucose: implications for targeting tumors with metabolically directed enzyme prodrug therapy.	Maltose	18-25	myelin basic protein	Homo sapiens	33-36
24563531-2	2014	Herein is described a novel, potent, and efficacious human 5-HT2C receptor agonist, (-)-trans-(2S,4R)-4-(3"[meta]-bromophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine (-)-MBP), that is a competitive antagonist and inverse agonist at human 5-HT2A and 5-HT2B receptors, respectively.	(-)-trans-(2s,4r)-4-(3"[meta]-bromophenyl)-n,n-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine	84-176	myelin basic protein	Homo sapiens	181-184
24529965-7	2014	RESULTS: Both MBP and PLP immunoreactivities in white matter at the level of the precommissural striatum were significantly lower in tissue from monkeys self-administering cocaine as compared to controls.	Cocaine	172-179	myelin basic protein	Homo sapiens	14-17
24131788-3	2014	A molecular switch, MBP317-347, originally designed to be a high-affinity switch for maltose and maltose-like polysaccharides, was demonstrated to be a low-affinity switch for glucose, that is, able to be activated by high concentrations (tens of millimolar) of glucose.	Glucose	262-269	myelin basic protein	Homo sapiens	20-23
25109087-7	2014	Hyperbaric oxygen improves mitochondrial function, inhibits lipid peroxidation transiently, impairs leukocyte adhesion to injured microvasculature, and reduces brain inflammation caused by the CO-induced adduct formation of myelin basic protein.	Oxygen	11-17	myelin basic protein	Homo sapiens	224-244
24956930-5	2014	We also carry out live-cell imaging of N19-OLGs co-transfected with fluorescent MBP and actin, and show that when actin filaments re-assemble after recovery from cytochalasin D treatment, MBP and actin are rapidly enriched and co-localized at certain sites at the plasma membrane and in newly-formed membrane ruffles.	Cytochalasin D	162-176	myelin basic protein	Homo sapiens	188-191
24131788-0	2014	The high-affinity maltose switch MBP317-347 has low affinity for glucose: implications for targeting tumors with metabolically directed enzyme prodrug therapy.	Glucose	65-72	myelin basic protein	Homo sapiens	33-36
24131788-3	2014	A molecular switch, MBP317-347, originally designed to be a high-affinity switch for maltose and maltose-like polysaccharides, was demonstrated to be a low-affinity switch for glucose, that is, able to be activated by high concentrations (tens of millimolar) of glucose.	Maltose	85-92	myelin basic protein	Homo sapiens	20-23
24131788-3	2014	A molecular switch, MBP317-347, originally designed to be a high-affinity switch for maltose and maltose-like polysaccharides, was demonstrated to be a low-affinity switch for glucose, that is, able to be activated by high concentrations (tens of millimolar) of glucose.	Maltose	97-104	myelin basic protein	Homo sapiens	20-23
24131788-3	2014	A molecular switch, MBP317-347, originally designed to be a high-affinity switch for maltose and maltose-like polysaccharides, was demonstrated to be a low-affinity switch for glucose, that is, able to be activated by high concentrations (tens of millimolar) of glucose.	Polysaccharides	110-125	myelin basic protein	Homo sapiens	20-23
24131788-3	2014	A molecular switch, MBP317-347, originally designed to be a high-affinity switch for maltose and maltose-like polysaccharides, was demonstrated to be a low-affinity switch for glucose, that is, able to be activated by high concentrations (tens of millimolar) of glucose.	Glucose	176-183	myelin basic protein	Homo sapiens	20-23
24391218-1	2014	Mannan (mannose)-binding protein (MBP) is a C-type serum lectin that plays a key role in innate immunity.	Mannans	0-6	myelin basic protein	Homo sapiens	34-37
24281246-5	2014	Thioflavin S-stained amyloid plaque intensity was reduced up to 60% by CTB-MBP incubation with human AD and 3xTgAD mice brain sections ex vivo.	thioflavin T	0-12	myelin basic protein	Homo sapiens	75-78
24391218-1	2014	Mannan (mannose)-binding protein (MBP) is a C-type serum lectin that plays a key role in innate immunity.	Mannose	8-15	myelin basic protein	Homo sapiens	34-37
24391218-2	2014	MBP forms large multimers (200-600 kDa) and exhibits broad specificity for mannose, N-acetylglucosamine, and fucose.	Mannose	75-82	myelin basic protein	Homo sapiens	0-3
24391218-2	2014	MBP forms large multimers (200-600 kDa) and exhibits broad specificity for mannose, N-acetylglucosamine, and fucose.	Acetylglucosamine	84-103	myelin basic protein	Homo sapiens	0-3
24391218-2	2014	MBP forms large multimers (200-600 kDa) and exhibits broad specificity for mannose, N-acetylglucosamine, and fucose.	Fucose	109-115	myelin basic protein	Homo sapiens	0-3
24391218-3	2014	MBP exhibits high affinity for unique oligosaccharides that have been isolated from human colorectal carcinoma (SW1116) cells and characterized as highly fucosylated high m.w.	Oligosaccharides	38-54	myelin basic protein	Homo sapiens	0-3
24391218-9	2014	The MBP-staining pattern in cancer mucosae significantly overlapped with that of Lewis b [Fucalpha1-2Galbeta1-3(Fucalpha1-4)GlcNAc] staining, but the Lewis b staining in normal tissues was not associated with MBP staining.	Acetylglucosamine	124-130	myelin basic protein	Homo sapiens	4-7
24134196-5	2013	In this report, we investigated the metal-affinity driven self-assembly between AuNPs and two engineered proteins, a His7-appended maltose binding protein (MBP-His) and a fluorescent His6-terminated mCherry protein.	Metals	36-41	myelin basic protein	Homo sapiens	156-159
25276831-0	2014	Glatiramer acetate and nanny proteins restrict access of the multiple sclerosis autoantigen myelin basic protein to the 26S proteasome.	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	92-112
25276831-4	2014	Interestingly, glatiramer acetate (GA), which is used to treat multiple sclerosis (MS) and is structurally similar to MBP, inhibits intracellular and in vitro proteasome-mediated MBP degradation.	Glatiramer Acetate	15-33	myelin basic protein	Homo sapiens	118-121
25276831-4	2014	Interestingly, glatiramer acetate (GA), which is used to treat multiple sclerosis (MS) and is structurally similar to MBP, inhibits intracellular and in vitro proteasome-mediated MBP degradation.	Glatiramer Acetate	15-33	myelin basic protein	Homo sapiens	179-182
25276831-4	2014	Interestingly, glatiramer acetate (GA), which is used to treat multiple sclerosis (MS) and is structurally similar to MBP, inhibits intracellular and in vitro proteasome-mediated MBP degradation.	Glatiramer Acetate	35-37	myelin basic protein	Homo sapiens	118-121
25276831-4	2014	Interestingly, glatiramer acetate (GA), which is used to treat multiple sclerosis (MS) and is structurally similar to MBP, inhibits intracellular and in vitro proteasome-mediated MBP degradation.	Glatiramer Acetate	35-37	myelin basic protein	Homo sapiens	179-182
25117253-4	2014	Carbohydrate-binding ability of MBP, its subcellular localization, and functional co-localization with ligand glycoprotein are assayed comparing with an inactive mutant MBP.	Carbohydrates	0-12	myelin basic protein	Homo sapiens	32-35
24141021-5	2014	Moreover, afobazole helped preserve both the levels and normal histological distribution of myelin basic protein, indicating a reduction in white matter injury.	2-((2-morpholino)ethylthio)-5-ethoxybenzimidazole	10-19	myelin basic protein	Homo sapiens	92-112
23998289-4	2014	The docking and screening from TCM database results indicate the vitamin B2, 3 beta-isodihydrocadambine, and caribine display higher binding affinity than maltose in maltose binding protein (MBP).	Riboflavin	65-75	myelin basic protein	Homo sapiens	166-189
23998289-4	2014	The docking and screening from TCM database results indicate the vitamin B2, 3 beta-isodihydrocadambine, and caribine display higher binding affinity than maltose in maltose binding protein (MBP).	Riboflavin	65-75	myelin basic protein	Homo sapiens	191-194
23998289-4	2014	The docking and screening from TCM database results indicate the vitamin B2, 3 beta-isodihydrocadambine, and caribine display higher binding affinity than maltose in maltose binding protein (MBP).	3 beta-isodihydrocadambine	77-103	myelin basic protein	Homo sapiens	166-189
23998289-4	2014	The docking and screening from TCM database results indicate the vitamin B2, 3 beta-isodihydrocadambine, and caribine display higher binding affinity than maltose in maltose binding protein (MBP).	3 beta-isodihydrocadambine	77-103	myelin basic protein	Homo sapiens	191-194
23998289-4	2014	The docking and screening from TCM database results indicate the vitamin B2, 3 beta-isodihydrocadambine, and caribine display higher binding affinity than maltose in maltose binding protein (MBP).	Caribine	109-117	myelin basic protein	Homo sapiens	166-189
23998289-4	2014	The docking and screening from TCM database results indicate the vitamin B2, 3 beta-isodihydrocadambine, and caribine display higher binding affinity than maltose in maltose binding protein (MBP).	Caribine	109-117	myelin basic protein	Homo sapiens	191-194
23998289-4	2014	The docking and screening from TCM database results indicate the vitamin B2, 3 beta-isodihydrocadambine, and caribine display higher binding affinity than maltose in maltose binding protein (MBP).	Maltose	155-162	myelin basic protein	Homo sapiens	166-189
23998289-4	2014	The docking and screening from TCM database results indicate the vitamin B2, 3 beta-isodihydrocadambine, and caribine display higher binding affinity than maltose in maltose binding protein (MBP).	Maltose	155-162	myelin basic protein	Homo sapiens	191-194
23998289-5	2014	However, the results of MD simulation shows the caribine-facilitated CRFR approach closer to MBP, the 3D structure conformation of MBP and CRFR complex forms compact structure.	Caribine	48-56	myelin basic protein	Homo sapiens	93-96
23998289-5	2014	However, the results of MD simulation shows the caribine-facilitated CRFR approach closer to MBP, the 3D structure conformation of MBP and CRFR complex forms compact structure.	Caribine	48-56	myelin basic protein	Homo sapiens	131-134
23998289-6	2014	Interestingly, the distance between the two proteins is reducing significantly after caribine dock into MBP binding site.	Caribine	85-93	myelin basic protein	Homo sapiens	104-107
23998289-8	2014	Hence, our finding suggests that caribine might be a potential lead compound to stimulate MBP and CRFR interaction, and help for baldless therapy in further study.	Caribine	33-41	myelin basic protein	Homo sapiens	90-93
24191053-1	2013	Kinetic folding of the large two-domain maltose binding protein (MBP; 370 residues) was studied at high structural resolution by an advanced hydrogen-exchange pulse-labeling mass-spectrometry method (HX MS).	Hydrogen	141-149	myelin basic protein	Homo sapiens	65-68
23918626-4	2013	The use of the recombinant fusion protein MBP-FAAH and the design of compound 11 as a suitable novel fluorinated substrate analogue allowed n-FABS screening to be efficiently performed using a very small amount of enzyme.	n-fabs	140-146	myelin basic protein	Homo sapiens	42-45
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	titanium dioxide	242-258	myelin basic protein	Homo sapiens	38-58
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	titanium dioxide	242-258	myelin basic protein	Homo sapiens	60-63
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	titanium dioxide	242-258	myelin basic protein	Homo sapiens	148-168
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	titanium dioxide	242-258	myelin basic protein	Homo sapiens	175-178
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	titanium dioxide	242-258	myelin basic protein	Homo sapiens	175-178
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	titanium dioxide	260-264	myelin basic protein	Homo sapiens	38-58
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	titanium dioxide	260-264	myelin basic protein	Homo sapiens	60-63
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	titanium dioxide	260-264	myelin basic protein	Homo sapiens	148-168
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	titanium dioxide	260-264	myelin basic protein	Homo sapiens	175-178
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	titanium dioxide	260-264	myelin basic protein	Homo sapiens	175-178
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	Platinum	275-284	myelin basic protein	Homo sapiens	38-58
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	Platinum	275-284	myelin basic protein	Homo sapiens	60-63
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	Platinum	275-284	myelin basic protein	Homo sapiens	148-168
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	Platinum	275-284	myelin basic protein	Homo sapiens	175-178
23500477-1	2013	A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO2) modified platinium electrode.	Platinum	275-284	myelin basic protein	Homo sapiens	175-178
23500477-3	2013	Gelatin-MBP and gelatin-TiO2-MBP electrodes were prepared by chemical immobilization of the substrates onto the platinium electrodes.	Platinum	112-121	myelin basic protein	Homo sapiens	29-32
23861868-0	2013	The effects of threonine phosphorylation on the stability and dynamics of the central molecular switch region of 18.5-kDa myelin basic protein.	Threonine	15-24	myelin basic protein	Homo sapiens	122-142
23800457-3	2013	Stimulation of MBP- and MOG-specific T cells in the presence of cis-UCA, significantly increased IL-10, and inhibited IFN-gamma production.	cis-Urocanic acid	64-71	myelin basic protein	Homo sapiens	15-18
24575330-5	2013	After polarization of MBP-primed Th1 cells to Th2 by gemfibrozil and other drugs, we observed that MBP-primed Th2 cells dose dependently inhibited the production of interleukin-1beta (IL-1beta) and nitric oxide (NO) in LPS-stimulated microglia via cell-to-cell contact.	Gemfibrozil	53-64	myelin basic protein	Homo sapiens	22-25
24575330-5	2013	After polarization of MBP-primed Th1 cells to Th2 by gemfibrozil and other drugs, we observed that MBP-primed Th2 cells dose dependently inhibited the production of interleukin-1beta (IL-1beta) and nitric oxide (NO) in LPS-stimulated microglia via cell-to-cell contact.	Gemfibrozil	53-64	myelin basic protein	Homo sapiens	99-102
24575330-5	2013	After polarization of MBP-primed Th1 cells to Th2 by gemfibrozil and other drugs, we observed that MBP-primed Th2 cells dose dependently inhibited the production of interleukin-1beta (IL-1beta) and nitric oxide (NO) in LPS-stimulated microglia via cell-to-cell contact.	Nitric Oxide	198-210	myelin basic protein	Homo sapiens	99-102
24252271-5	2013	OLs become vulnerable when they are just beginning to generate myelin basic protein in preparation for myelinating axons, and they remain vulnerable throughout later stages of myelination.	N-biotin-C-Co4(mu3-O)4(Py)4(H2O)4-beta-alanine	0-3	myelin basic protein	Homo sapiens	63-83
23500430-0	2013	Myelin basic protein: structural characterization of spherulites formation and preventive action of trehalose.	Trehalose	100-109	myelin basic protein	Homo sapiens	0-20
23500430-6	2013	Moreover, study of protein conformational states by SDS-PAGE, let us to state that trehalose completely avoid autocatalytic cleavage properties of MBP up to 4 days of incubation at 37  C and pH 7.4.	Trehalose	83-92	myelin basic protein	Homo sapiens	147-150
23149755-4	2013	By rational utilization of the XmnI and EcoRV restriction sites, a PCR fragment encoding dTMP-GH was inserted into the plasmid vector pMAL-p2X at the position right after Xa factor cleavage site, in frame with maltose-binding protein (MBP) gene.	dtmp-gh	89-96	myelin basic protein	Homo sapiens	210-233
23149755-4	2013	By rational utilization of the XmnI and EcoRV restriction sites, a PCR fragment encoding dTMP-GH was inserted into the plasmid vector pMAL-p2X at the position right after Xa factor cleavage site, in frame with maltose-binding protein (MBP) gene.	dtmp-gh	89-96	myelin basic protein	Homo sapiens	235-238
23073152-7	2013	The best tripartite fusion was identified as MBP-(EAAAK)(3)-GFP-(GGGGS)(3)-HepA, which shows potential to facilitate the production of HepA and its application in industrial preparation of low molecular weight heparin.	Heparin	210-217	myelin basic protein	Homo sapiens	45-48
23581466-5	2013	When coupled to the maltose binding protein (MBP), our calcium-responsive tag efficiently purified the fusion protein.	Calcium	55-62	myelin basic protein	Homo sapiens	20-43
23581466-5	2013	When coupled to the maltose binding protein (MBP), our calcium-responsive tag efficiently purified the fusion protein.	Calcium	55-62	myelin basic protein	Homo sapiens	45-48
23581466-6	2013	Furthermore, when the MBP was appended to green fluorescent protein (GFP), beta-lactamase, or a thermostable alcohol dehydrogenase (AdhD), these constructs could also be purified by calcium-induced precipitation.	Calcium	182-189	myelin basic protein	Homo sapiens	22-25
23411612-6	2013	MBP conjugated fluorescent dye-encapsulating liposomes served to provide recognition and signal amplification in a competitive assay for maltose using amylose magnetic beads in a microtiter plate-based format.	Maltose	137-144	myelin basic protein	Homo sapiens	0-3
23411612-6	2013	MBP conjugated fluorescent dye-encapsulating liposomes served to provide recognition and signal amplification in a competitive assay for maltose using amylose magnetic beads in a microtiter plate-based format.	Amylose	151-158	myelin basic protein	Homo sapiens	0-3
23329142-8	2013	When copper and zinc were incorporated into hEC-SOD before MBP tag cleavage, the enzymatic activity was higher than when the metal ions were bound to the purified protein after MBP tag cleavage.	Copper	5-11	myelin basic protein	Homo sapiens	59-62
23329142-8	2013	When copper and zinc were incorporated into hEC-SOD before MBP tag cleavage, the enzymatic activity was higher than when the metal ions were bound to the purified protein after MBP tag cleavage.	Copper	5-11	myelin basic protein	Homo sapiens	177-180
23164828-7	2013	Patients with NMO with lower serum UA concentrations tended to be positive for OB, to have higher CSF protein and MBP concentrations, and to have higher WBC counts and 24 hour IgG index, but no correlation was statistically significant.	Uric Acid	35-37	myelin basic protein	Homo sapiens	114-117
23400970-3	2013	We have previously demonstrated that the nonhomologous recombination of the genes encoding maltose binding protein (MBP) and TEM1 beta-lactamase (BLA) can result in genes that confer maltose-dependent resistance to beta-lactam antibiotics even though the encoded proteins are not allosteric enzymes.	Maltose	91-98	myelin basic protein	Homo sapiens	116-119
23400970-3	2013	We have previously demonstrated that the nonhomologous recombination of the genes encoding maltose binding protein (MBP) and TEM1 beta-lactamase (BLA) can result in genes that confer maltose-dependent resistance to beta-lactam antibiotics even though the encoded proteins are not allosteric enzymes.	beta-Lactams	130-141	myelin basic protein	Homo sapiens	91-114
23400970-3	2013	We have previously demonstrated that the nonhomologous recombination of the genes encoding maltose binding protein (MBP) and TEM1 beta-lactamase (BLA) can result in genes that confer maltose-dependent resistance to beta-lactam antibiotics even though the encoded proteins are not allosteric enzymes.	beta-Lactams	130-141	myelin basic protein	Homo sapiens	116-119
22933379-0	2013	How maltose influences structural changes to bind to maltose-binding protein: results from umbrella sampling simulation.	Maltose	4-11	myelin basic protein	Homo sapiens	53-76
22933379-1	2013	A well-studied periplasmic-binding protein involved in the abstraction of maltose is maltose-binding protein (MBP), which undergoes a ligand-induced conformational transition from an open (ligand-free) to a closed (ligand-bound) state.	Maltose	74-81	myelin basic protein	Homo sapiens	85-108
22933379-1	2013	A well-studied periplasmic-binding protein involved in the abstraction of maltose is maltose-binding protein (MBP), which undergoes a ligand-induced conformational transition from an open (ligand-free) to a closed (ligand-bound) state.	Maltose	74-81	myelin basic protein	Homo sapiens	110-113
22933379-2	2013	Umbrella sampling simulations have been us to estimate the free energy of binding of maltose to MBP and to trace the potential of mean force of the unbinding event using the center-of-mass distance between the protein and ligand as the reaction coordinate.	Maltose	85-92	myelin basic protein	Homo sapiens	96-99
24025570-3	2013	The maltose binding protein-fused heavy chain variable region (MBP-V(H)) of an antibody that recognizes the C-terminal fragment of human osteocalcin (bone Gla protein, BGP), a biomarker for bone-related diseases, was immobilized onto microplate wells, and the antigen together with streptavidin (SA)-fused light chain variable region of the same antibody (SA-V(L)) was added and incubated.	Maltose	4-11	myelin basic protein	Homo sapiens	63-66
22897631-11	2013	NVD may provide some neuroprotection, indicated by anti-NF-160 and anti-MBP, which was markedly lowered in ergocalciferol patients.	Ergocalciferols	107-121	myelin basic protein	Homo sapiens	72-75
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	diester	6-13	myelin basic protein	Homo sapiens	90-93
23092790-3	2013	We describe an immunohistochemical analysis and a fluorescence polarization binding assay using purified myelin basic protein (MBP) that provides quantitative evidence that MBP is the molecular binding partner of previously described myelin-selective fluorescent dyes such as BMB, GE3082, and GE3111.	bmb	276-279	myelin basic protein	Homo sapiens	105-125
23092790-3	2013	We describe an immunohistochemical analysis and a fluorescence polarization binding assay using purified myelin basic protein (MBP) that provides quantitative evidence that MBP is the molecular binding partner of previously described myelin-selective fluorescent dyes such as BMB, GE3082, and GE3111.	bmb	276-279	myelin basic protein	Homo sapiens	127-130
23092790-3	2013	We describe an immunohistochemical analysis and a fluorescence polarization binding assay using purified myelin basic protein (MBP) that provides quantitative evidence that MBP is the molecular binding partner of previously described myelin-selective fluorescent dyes such as BMB, GE3082, and GE3111.	bmb	276-279	myelin basic protein	Homo sapiens	173-176
23092790-3	2013	We describe an immunohistochemical analysis and a fluorescence polarization binding assay using purified myelin basic protein (MBP) that provides quantitative evidence that MBP is the molecular binding partner of previously described myelin-selective fluorescent dyes such as BMB, GE3082, and GE3111.	4-(2-(4-(2-(4-aminophenyl)ethenyl)-3-methoxyphenyl)ethenyl)benzonitrile	281-287	myelin basic protein	Homo sapiens	105-125
23092790-3	2013	We describe an immunohistochemical analysis and a fluorescence polarization binding assay using purified myelin basic protein (MBP) that provides quantitative evidence that MBP is the molecular binding partner of previously described myelin-selective fluorescent dyes such as BMB, GE3082, and GE3111.	4-(2-(4-(2-(4-aminophenyl)ethenyl)-3-methoxyphenyl)ethenyl)benzonitrile	281-287	myelin basic protein	Homo sapiens	127-130
23092790-3	2013	We describe an immunohistochemical analysis and a fluorescence polarization binding assay using purified myelin basic protein (MBP) that provides quantitative evidence that MBP is the molecular binding partner of previously described myelin-selective fluorescent dyes such as BMB, GE3082, and GE3111.	4-(2-(4-(2-(4-aminophenyl)ethenyl)-3-methoxyphenyl)ethenyl)benzonitrile	281-287	myelin basic protein	Homo sapiens	173-176
23092790-3	2013	We describe an immunohistochemical analysis and a fluorescence polarization binding assay using purified myelin basic protein (MBP) that provides quantitative evidence that MBP is the molecular binding partner of previously described myelin-selective fluorescent dyes such as BMB, GE3082, and GE3111.	1-methylsulfonyl-4-(2-(4-(2-(4-aminophenyl)ethenyl)-3-methoxyphenyl)ethenyl)benzene	293-299	myelin basic protein	Homo sapiens	105-125
23092790-3	2013	We describe an immunohistochemical analysis and a fluorescence polarization binding assay using purified myelin basic protein (MBP) that provides quantitative evidence that MBP is the molecular binding partner of previously described myelin-selective fluorescent dyes such as BMB, GE3082, and GE3111.	1-methylsulfonyl-4-(2-(4-(2-(4-aminophenyl)ethenyl)-3-methoxyphenyl)ethenyl)benzene	293-299	myelin basic protein	Homo sapiens	127-130
23092790-3	2013	We describe an immunohistochemical analysis and a fluorescence polarization binding assay using purified myelin basic protein (MBP) that provides quantitative evidence that MBP is the molecular binding partner of previously described myelin-selective fluorescent dyes such as BMB, GE3082, and GE3111.	1-methylsulfonyl-4-(2-(4-(2-(4-aminophenyl)ethenyl)-3-methoxyphenyl)ethenyl)benzene	293-299	myelin basic protein	Homo sapiens	173-176
23520443-1	2013	IgGs from patients with multiple sclerosis and systemic lupus erythematosus (SLE) purified on MBP-Sepharose in contrast to canonical proteases hydrolyze effectively only myelin basic protein (MBP), but not many other tested proteins.	Sepharose	98-107	myelin basic protein	Homo sapiens	94-97
23520443-1	2013	IgGs from patients with multiple sclerosis and systemic lupus erythematosus (SLE) purified on MBP-Sepharose in contrast to canonical proteases hydrolyze effectively only myelin basic protein (MBP), but not many other tested proteins.	Sepharose	98-107	myelin basic protein	Homo sapiens	170-190
23520443-1	2013	IgGs from patients with multiple sclerosis and systemic lupus erythematosus (SLE) purified on MBP-Sepharose in contrast to canonical proteases hydrolyze effectively only myelin basic protein (MBP), but not many other tested proteins.	Sepharose	98-107	myelin basic protein	Homo sapiens	192-195
23528601-2	2013	Before perfusions, we investigated the lymphocyte sensitivity to methylprednisolone in vitro in the reaction of leukocyte migration with myelin basic protein in each patient.	Methylprednisolone	65-83	myelin basic protein	Homo sapiens	137-157
22739543-10	2012	The ranking order of CL(max) values for monoester phthalate formation in DBP, BBzP and DEHP hydrolysis was BBzP to MBzP&gt;=DBP to MBP&gt;DEHP to MEHP&gt;BBzP to MBP.	phthalic acid	50-59	myelin basic protein	Homo sapiens	131-134
22739543-10	2012	The ranking order of CL(max) values for monoester phthalate formation in DBP, BBzP and DEHP hydrolysis was BBzP to MBzP&gt;=DBP to MBP&gt;DEHP to MEHP&gt;BBzP to MBP.	phthalic acid	50-59	myelin basic protein	Homo sapiens	162-165
23315809-0	2012	Association of  the genes for tumor necrosis factor-alpha and myelin basic protein with delayed  encephalopathy after acute carbon monoxide poisoning.	Carbon Monoxide	124-139	myelin basic protein	Homo sapiens	62-82
23315809-2	2012	In order to assess the role of genetic factors in this mechanism, we studied the association between tumor necrosis factor-alpha308 (TNF-alpha308) and myelin basic protein (MBP) 5"-side tetranucleotide repetitive sequence (TGGA) n gene polymorphism and DEACMP.	tetranucleotide	186-201	myelin basic protein	Homo sapiens	151-171
23315809-2	2012	In order to assess the role of genetic factors in this mechanism, we studied the association between tumor necrosis factor-alpha308 (TNF-alpha308) and myelin basic protein (MBP) 5"-side tetranucleotide repetitive sequence (TGGA) n gene polymorphism and DEACMP.	tetranucleotide	186-201	myelin basic protein	Homo sapiens	173-176
23046344-0	2012	Mapping the conformational stability of maltose binding protein at the residue scale using nuclear magnetic resonance hydrogen exchange experiments.	Hydrogen	118-126	myelin basic protein	Homo sapiens	40-63
23046344-2	2012	The maltose binding protein (MBP), a protein that belongs to the maltose transport system, has a structure composed of two globular domains separated by a rigid-body "hinge bending".	Maltose	4-11	myelin basic protein	Homo sapiens	29-32
23046344-3	2012	Here we determined, by using hydrogen exchange (HX) nuclear magnetic resonance experiments, the apparent stabilization free energies of 101 residues of MBP bound to beta-cyclodextrin (MBP-betaCD) under native conditions.	Hydrogen	29-37	myelin basic protein	Homo sapiens	152-155
23046344-3	2012	Here we determined, by using hydrogen exchange (HX) nuclear magnetic resonance experiments, the apparent stabilization free energies of 101 residues of MBP bound to beta-cyclodextrin (MBP-betaCD) under native conditions.	Hydrogen	29-37	myelin basic protein	Homo sapiens	184-187
23046344-3	2012	Here we determined, by using hydrogen exchange (HX) nuclear magnetic resonance experiments, the apparent stabilization free energies of 101 residues of MBP bound to beta-cyclodextrin (MBP-betaCD) under native conditions.	betadex	165-182	myelin basic protein	Homo sapiens	152-155
23046344-3	2012	Here we determined, by using hydrogen exchange (HX) nuclear magnetic resonance experiments, the apparent stabilization free energies of 101 residues of MBP bound to beta-cyclodextrin (MBP-betaCD) under native conditions.	betadex	165-182	myelin basic protein	Homo sapiens	184-187
23046344-5	2012	Further, HX experiments were performed using guanidine hydrochloride under subdenaturing conditions to discriminate between local fluctuations and global unfolding events and to determine the MBP-betaCD energy landscape.	betadex	196-202	myelin basic protein	Homo sapiens	192-195
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	diester	6-13	myelin basic protein	Homo sapiens	129-132
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	phthalic acid	14-24	myelin basic protein	Homo sapiens	90-93
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	phthalic acid	14-24	myelin basic protein	Homo sapiens	129-132
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	monobutyl phthalate	66-88	myelin basic protein	Homo sapiens	90-93
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	monobutyl phthalate	66-88	myelin basic protein	Homo sapiens	129-132
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	monobutyl phthalate	105-127	myelin basic protein	Homo sapiens	90-93
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	mono-benzyl phthalate	138-158	myelin basic protein	Homo sapiens	90-93
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	mono-benzyl phthalate	160-164	myelin basic protein	Homo sapiens	90-93
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	butylbenzyl phthalate	171-175	myelin basic protein	Homo sapiens	90-93
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	mono-(2-ethylhexyl)phthalate	181-209	myelin basic protein	Homo sapiens	90-93
22739543-3	2012	These diester phthalates were hydrolyzed to monoester phthalates (mono-n-butyl phthalate (MBP) from DBP, mono-n-butyl phthalate (MBP) and monobenzyl phthalate (MBzP) from BBzP, and mono(2-ethylhexyl) phthalate (MEHP)) by human liver microsomes.	mono-(2-ethylhexyl)phthalate	211-215	myelin basic protein	Homo sapiens	90-93
22538354-0	2012	Effect of phosphorylation of phosphatidylinositol on myelin basic protein-mediated binding of actin filaments to lipid bilayers in vitro.	Phosphatidylinositols	29-49	myelin basic protein	Homo sapiens	53-73
22879602-3	2012	The current study identified another novel property of gemfibrozil in stimulating the expression of myelin-specific genes (myelin basic protein, myelin oligodendrocyte glycoprotein, 2",3"-cyclic-nucleotide 3"-phosphodiesterase, and proteolipid protein (PLP)) in primary human oligodendrocytes, mixed glial cells, and spinal cord organotypic cultures.	Gemfibrozil	55-66	myelin basic protein	Homo sapiens	123-143
22955068-1	2012	PURPOSE: The main objective of this study was to assess the intrasubject and intersubjects variability of 18F-FDG uptake in liver (LIV) and mediastinum (MBP) among patients with diffuse large B-cell lymphoma (DLBCL), treated with different chemotherapy regimens.	Fluorodeoxyglucose F18	106-113	myelin basic protein	Homo sapiens	153-156
22955068-5	2012	The intersubject variability of 18F-FDG uptake in LIV and MBP ranged from 20.2% to 25.4%.	Fluorodeoxyglucose F18	32-39	myelin basic protein	Homo sapiens	58-61
22538354-3	2012	Here we investigate the effect of increased negative charge of the lipid bilayer due to phosphorylation of phosphatidylinositol (PI) on MBP-mediated binding of actin to the lipid bilayer, by substituting phosphatidylinositol 4-phosphate or phosphatidylinositol 4,5-bisphosphate for PI in phosphatidylcholine/phosphatidylglycerol lipid vesicles.	Phosphatidylinositols	107-127	myelin basic protein	Homo sapiens	136-139
22705794-2	2012	We investigated the three-dimensional folding of a 1 Mbp region of human chromosome 11 containing the beta-globin genes by integrating looping interactions of the CCCTC-binding insulator protein CTCF determined comprehensively by chromosome conformation capture (3C) into a polymer model of chromatin.	Polymers	274-281	myelin basic protein	Homo sapiens	53-56
22781164-1	2012	In contrast to canonical proteases, myelin basic protein (MBP)-Sepharose-purified IgG from multiple sclerosis (MS) and systemic lupus erythematosus (SLE) patients efficiently hydrolyze only MBP, but not many other tested proteins.	Sepharose	63-72	myelin basic protein	Homo sapiens	36-56
22781164-1	2012	In contrast to canonical proteases, myelin basic protein (MBP)-Sepharose-purified IgG from multiple sclerosis (MS) and systemic lupus erythematosus (SLE) patients efficiently hydrolyze only MBP, but not many other tested proteins.	Sepharose	63-72	myelin basic protein	Homo sapiens	58-61
22781164-1	2012	In contrast to canonical proteases, myelin basic protein (MBP)-Sepharose-purified IgG from multiple sclerosis (MS) and systemic lupus erythematosus (SLE) patients efficiently hydrolyze only MBP, but not many other tested proteins.	Sepharose	63-72	myelin basic protein	Homo sapiens	190-193
22258479-0	2012	Fractional anisotropy in the centrum semiovale as a quantitative indicator of cerebral white matter damage in the subacute phase in patients with carbon monoxide poisoning: correlation with the concentration of myelin basic protein in cerebrospinal fluid.	Carbon Monoxide	146-161	myelin basic protein	Homo sapiens	211-231
22542401-7	2012	We demonstrate that the AFBN pre-treatment protocol for CSF significantly enhances the measurement of glutamine synthetase (GS) and myelin basic protein (MBP) in CSF but does not affect detection of glial fibrillary protein (GFAP), amyloid beta 42 (Abeta42), total tau (t-tau) or phosphorylated tau (p-tau).	afbn	24-28	myelin basic protein	Homo sapiens	132-152
22542401-7	2012	We demonstrate that the AFBN pre-treatment protocol for CSF significantly enhances the measurement of glutamine synthetase (GS) and myelin basic protein (MBP) in CSF but does not affect detection of glial fibrillary protein (GFAP), amyloid beta 42 (Abeta42), total tau (t-tau) or phosphorylated tau (p-tau).	afbn	24-28	myelin basic protein	Homo sapiens	154-157
22222856-2	2012	The objective of this work was to determine if BHT-3009, a DNA plasmid-encoding myelin basic protein (MBP), reduces the risk of new lesions becoming PBH, compared to placebo, and to test if pre-treatment serum anti-MBP antibody levels impact on the effect of BHT-3009 treatment.	Butylated Hydroxytoluene	47-50	myelin basic protein	Homo sapiens	80-100
22805152-14	2012	The AS601245 or JNK antisense ODN group had significantly increased MBP and decreased GFAP expression in the white matter on P11 than the vehicle or scrambled ODN group.	1,3-benzothiazol-2-yl(2-((2-(3-pyridinyl)ethyl)amino)-4-pyrimidinyl)acetonitrile	4-12	myelin basic protein	Homo sapiens	68-71
22222856-2	2012	The objective of this work was to determine if BHT-3009, a DNA plasmid-encoding myelin basic protein (MBP), reduces the risk of new lesions becoming PBH, compared to placebo, and to test if pre-treatment serum anti-MBP antibody levels impact on the effect of BHT-3009 treatment.	Butylated Hydroxytoluene	47-50	myelin basic protein	Homo sapiens	102-105
22222856-7	2012	However, there was a significant interaction between anti-MBP antibodies and treatment effect: patients receiving 0.5 mg BHT-3009 showed a reduced risk of PBH with higher antibody levels compared to placebo (p &lt; 0.01).	Butylated Hydroxytoluene	121-124	myelin basic protein	Homo sapiens	58-61
22621845-7	2012	Using stepwise regression analysis with Age, BMI, SBP, DBP, MBP: Dtf was dependent with age (P&lt;10(-4)) and SBP (P&lt;0.01); PWVtf with age (P&lt;0.0001), SBP (P&lt;0.01) and DBP (P&lt;0.05); pOpscore( ) was dependent only to age (P&lt;10(-4)).	dtf	65-68	myelin basic protein	Homo sapiens	60-63
22642799-12	2012	Glatiramer acetate appears to mimic the antigenic properties of myelin basic protein (MBP), and by doing so, alters T-cell activation in the periphery.	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	64-84
22642799-12	2012	Glatiramer acetate appears to mimic the antigenic properties of myelin basic protein (MBP), and by doing so, alters T-cell activation in the periphery.	Glatiramer Acetate	0-18	myelin basic protein	Homo sapiens	86-89
22609403-4	2012	We found that 21.5-kDa MBP contains two non-traditional PY-nuclear-localization signals, and that arginine and lysine residues within these motifs were involved in subcellular trafficking of this protein to the nucleus, where it may have functional roles during myelinogenesis.	Arginine	98-106	myelin basic protein	Homo sapiens	23-26
22609403-4	2012	We found that 21.5-kDa MBP contains two non-traditional PY-nuclear-localization signals, and that arginine and lysine residues within these motifs were involved in subcellular trafficking of this protein to the nucleus, where it may have functional roles during myelinogenesis.	Lysine	111-117	myelin basic protein	Homo sapiens	23-26
22770406-9	2012	MS patients with lower serum UA levels tended to have higher white blood cell counts and myelin basic protein level.	Uric Acid	29-31	myelin basic protein	Homo sapiens	89-109
22249765-0	2012	Classic 18.5- and 21.5-kDa myelin basic protein isoforms associate with cytoskeletal and SH3-domain proteins in the immortalized N19-oligodendroglial cell line stimulated by phorbol ester and IGF-1.	Phorbol Esters	174-187	myelin basic protein	Homo sapiens	27-47
22374748-2	2012	The mass spectrum of BNZP yields a unique benzoyl-group containing fragment at m/z 122 and an additional major fragment at m/z 69 that allows its discrimination from the three MBP regioisomers.	bnzp	21-25	myelin basic protein	Homo sapiens	176-179
22249765-5	2012	We show that MBP redistributes to distinct "membrane-ruffled" regions of the plasma membrane where it co-localizes with actin and tubulin, and with the SH3-domain-containing proteins cortactin and ZO-1, when stimulated with PMA, a potent activator of the protein kinase C pathway.	Tetradecanoylphorbol Acetate	224-227	myelin basic protein	Homo sapiens	13-16
22482529-2	2012	All MBP-NDM-1 fusion proteins were soluble; however, only one, MBP-NDM-1Delta36, exhibited high activity and bound 2 equiv of Zn(II).	Zinc	126-128	myelin basic protein	Homo sapiens	4-7
22482529-2	2012	All MBP-NDM-1 fusion proteins were soluble; however, only one, MBP-NDM-1Delta36, exhibited high activity and bound 2 equiv of Zn(II).	Zinc	126-128	myelin basic protein	Homo sapiens	63-66
22285427-3	2012	MBP-FGF was immobilized on polystyrene (PS) surfaces by spontaneous adsorption.	Polystyrenes	27-38	myelin basic protein	Homo sapiens	0-3
22285427-3	2012	MBP-FGF was immobilized on polystyrene (PS) surfaces by spontaneous adsorption.	Polystyrenes	40-42	myelin basic protein	Homo sapiens	0-3
22285427-5	2012	Human adipose-derived stem cell (hASC) adhesion to MBP-bFGF immobilized on a PS surface (PS-MBP-bFGF) was inhibited by heparin.	Heparin	119-126	myelin basic protein	Homo sapiens	51-54
22285427-5	2012	Human adipose-derived stem cell (hASC) adhesion to MBP-bFGF immobilized on a PS surface (PS-MBP-bFGF) was inhibited by heparin.	Heparin	119-126	myelin basic protein	Homo sapiens	92-95
22285427-9	2012	These results suggest that the mechanism of hASC adhesion to MBP-bFGF immobilized on a PS substrate is mediated by a specific interaction between bFGF and heparin, and that the adhesion mechanism might provide an insight into the design of biomaterials to control the fate of stem cells.	Heparin	155-162	myelin basic protein	Homo sapiens	61-64
21783334-2	2012	He showed increased cerebrospinal fluid cell counts and high myelin basic protein levels, which responded well to steroid pulse therapy.	Steroids	114-121	myelin basic protein	Homo sapiens	61-81
22157807-2	2012	In this study, 400 mg of nilotinib was administered twice daily to the patients with myeloid (MBP, n=105) or lymphoid blastic phase (LBP, n=31) CML.	nilotinib	25-34	myelin basic protein	Homo sapiens	94-97
22434709-4	2012	A similar situation was observed for IgG from patients with multiple sclerosis and HIV-infected patients, which after purification on myelin basic protein (MBP)-Sepharose and RT-Sepharose specifically hydrolyze only MBP and RT, respectively.	Sepharose	161-170	myelin basic protein	Homo sapiens	134-154
22434709-4	2012	A similar situation was observed for IgG from patients with multiple sclerosis and HIV-infected patients, which after purification on myelin basic protein (MBP)-Sepharose and RT-Sepharose specifically hydrolyze only MBP and RT, respectively.	Sepharose	161-170	myelin basic protein	Homo sapiens	156-159
22434709-4	2012	A similar situation was observed for IgG from patients with multiple sclerosis and HIV-infected patients, which after purification on myelin basic protein (MBP)-Sepharose and RT-Sepharose specifically hydrolyze only MBP and RT, respectively.	Sepharose	178-187	myelin basic protein	Homo sapiens	216-219
22429267-6	2012	Fibers with NFH and MBP show NaCh clusters at nodal sites as expected, but surprisingly, NaCh accumulations are also seen in unmyelinated fibers with NFH, and in fibers with NFH that lack Schwann cell associations.	nach	29-33	myelin basic protein	Homo sapiens	20-23
21878453-2	2012	Through its enzymatic activity PAD2 converts myelin basic protein (MBP) arginines into citrullines - an event that may favour autoimmunity - while peptidylarginine deiminase 4 (PAD4) is involved in chromatin remodelling.	Arginine	72-81	myelin basic protein	Homo sapiens	45-65
21878453-2	2012	Through its enzymatic activity PAD2 converts myelin basic protein (MBP) arginines into citrullines - an event that may favour autoimmunity - while peptidylarginine deiminase 4 (PAD4) is involved in chromatin remodelling.	Arginine	72-81	myelin basic protein	Homo sapiens	67-70
22173104-3	2012	In The Comparative Toxicogenomics Database, BPA and five most frequently curated PAEs (DEHP/MEHP and DBP/BBP/MBP) were found to have 1932 and 484 interactions with genes/proteins, respectively.	bisphenol A	44-47	myelin basic protein	Homo sapiens	109-112
22325262-2	2012	Using molecular simulations, we predicted that the binding interface between DARPin off7 and its ligand (maltose binding protein; MBP) is characterized by a hot-spot motif in which binding energy is largely concentrated on a few amino acids.	Maltose	105-112	myelin basic protein	Homo sapiens	130-133
22325262-3	2012	To experimentally test this prediction, we fused MBP to a transmembrane domain to properly orient the protein into a polymer-cushioned lipid bilayer, and characterized its interaction with off7 using force spectroscopy.	Polymers	117-124	myelin basic protein	Homo sapiens	49-52
22080040-7	2012	Kinase activity derived from positive Q-column fractions bound to amylose-maltose-binding protein (MBP)-apoptin and could be eluted with ATP only in the presence of the cofactor Mg(2+).	Adenosine Triphosphate	137-140	myelin basic protein	Homo sapiens	66-97
22130998-3	2012	Positive protein-protein interactions (PPIs) can be detected after pull-down of the MBP-tagged prey protein using amylose beads followed by the bioluminescence detection of the bound eGFP-luc-tagged bait protein.	Amylose	114-121	myelin basic protein	Homo sapiens	84-87
22428786-6	2012	In general, the youngest girls with less advanced pubertal development had the highest first morning urinary concentration of the monobutyl phthalate isoforms ( MBP((i+n))), monobenzyl phthalate (MBzP), metabolites of di-(2-ethylhexyl) phthalate ( DEHPm) and of di-iso-nonyl phthalate ( DINPm).	monobutyl phthalate	130-149	myelin basic protein	Homo sapiens	161-164
22736004-7	2012	InvR-MS2 could be effectively purified along with associated proteins, such as Hfq, using maltose binding protein fused to the MS2 coat protein (MBP-MS2) immobilized on an amylose column.	Amylose	172-179	myelin basic protein	Homo sapiens	145-148
23053570-2	2012	This study provides further evidence that radial positioning depends on features of corresponding ~1 Mbp chromatin domains (CDs), which represent the basic units of higher-order chromatin organization.	cds	124-127	myelin basic protein	Homo sapiens	101-104
22509216-2	2012	This approach uses 2-F-labeled maltose as a spy ligand to indirectly probe protein-ligand or protein-protein interactions of proteins fused or tagged to the maltose-binding protein (MBP).	2-F	19-22	myelin basic protein	Homo sapiens	157-180
22509216-2	2012	This approach uses 2-F-labeled maltose as a spy ligand to indirectly probe protein-ligand or protein-protein interactions of proteins fused or tagged to the maltose-binding protein (MBP).	2-F	19-22	myelin basic protein	Homo sapiens	182-185
22509216-2	2012	This approach uses 2-F-labeled maltose as a spy ligand to indirectly probe protein-ligand or protein-protein interactions of proteins fused or tagged to the maltose-binding protein (MBP).	Maltose	31-38	myelin basic protein	Homo sapiens	157-180
22509216-2	2012	This approach uses 2-F-labeled maltose as a spy ligand to indirectly probe protein-ligand or protein-protein interactions of proteins fused or tagged to the maltose-binding protein (MBP).	Maltose	31-38	myelin basic protein	Homo sapiens	182-185
22509216-3	2012	The key feature is the simultaneous NMR observation of both (19)F NMR signals of gluco/manno-type-2-F-maltose-isomers; one isomer (alpha-gluco-type) binds to MBP and senses the protein interaction, and the nonbinding isomers (beta-gluco- and/or alpha/beta-manno-type) are utilized as internal references.	gluco	81-86	myelin basic protein	Homo sapiens	158-161
22509216-3	2012	The key feature is the simultaneous NMR observation of both (19)F NMR signals of gluco/manno-type-2-F-maltose-isomers; one isomer (alpha-gluco-type) binds to MBP and senses the protein interaction, and the nonbinding isomers (beta-gluco- and/or alpha/beta-manno-type) are utilized as internal references.	manno	87-92	myelin basic protein	Homo sapiens	158-161
22509216-3	2012	The key feature is the simultaneous NMR observation of both (19)F NMR signals of gluco/manno-type-2-F-maltose-isomers; one isomer (alpha-gluco-type) binds to MBP and senses the protein interaction, and the nonbinding isomers (beta-gluco- and/or alpha/beta-manno-type) are utilized as internal references.	Maltose	102-109	myelin basic protein	Homo sapiens	158-161
22509216-4	2012	Moreover, this reporter system was used for relative affinity studies of fluorinated and nonfluorinated carbohydrates to the maltose-binding protein, which were found to be in perfect agreement with published X-ray data.	Carbohydrates	104-117	myelin basic protein	Homo sapiens	125-148
21723567-8	2011	Proliferation of both freshly isolated CD4+ T cells and MBP-specific T cells was significantly inhibited by 1,25(OH)(2) Vitamin D.	1,25(oh)(	108-117	myelin basic protein	Homo sapiens	56-59
23091637-11	2012	CONCLUSIONS: hES-derived OPCs transplanted 2 hours after contusive SCI survive and differentiate into OLs that produce MBP.	N-biotin-C-Co4(mu3-O)4(Py)4(H2O)4-beta-alanine	102-105	myelin basic protein	Homo sapiens	119-122
22720063-10	2012	Mutagenesis and molecular modeling of an intact TEM-1 domain near MBP within the RG13 framework indicated a close surface proximity of the two domains with maltose switching being critically dependent on MBP linker anchoring residues and linker length.	Maltose	156-163	myelin basic protein	Homo sapiens	66-69
22720063-10	2012	Mutagenesis and molecular modeling of an intact TEM-1 domain near MBP within the RG13 framework indicated a close surface proximity of the two domains with maltose switching being critically dependent on MBP linker anchoring residues and linker length.	Maltose	156-163	myelin basic protein	Homo sapiens	204-207
22720063-11	2012	Structural analysis indicated that the linker attachment sites on MBP are at a site that, upon maltose binding, harbors both the largest local Calpha distance changes and displays surface curvature changes, from concave to relatively flat becoming thus less sterically intrusive.	Maltose	95-102	myelin basic protein	Homo sapiens	66-69
21723567-8	2011	Proliferation of both freshly isolated CD4+ T cells and MBP-specific T cells was significantly inhibited by 1,25(OH)(2) Vitamin D.	Vitamin D	118-129	myelin basic protein	Homo sapiens	56-59
21242286-10	2011	A significant correlation was identified between MBP and (mean)Cho/Cr ratio.	CAV protocol	63-66	myelin basic protein	Homo sapiens	49-52
22035235-4	2011	As a model study, maltose-binding protein (MBP) was dually labeled via incorporation of rho-azido-l-phenylalanine and cysteine at specific positions, immobilized on a surface, and subjected to smFRET analysis under native and denaturing conditions.	rho-azido-l-phenylalanine	88-113	myelin basic protein	Homo sapiens	18-41
22035235-4	2011	As a model study, maltose-binding protein (MBP) was dually labeled via incorporation of rho-azido-l-phenylalanine and cysteine at specific positions, immobilized on a surface, and subjected to smFRET analysis under native and denaturing conditions.	rho-azido-l-phenylalanine	88-113	myelin basic protein	Homo sapiens	43-46
22035235-4	2011	As a model study, maltose-binding protein (MBP) was dually labeled via incorporation of rho-azido-l-phenylalanine and cysteine at specific positions, immobilized on a surface, and subjected to smFRET analysis under native and denaturing conditions.	Cysteine	118-126	myelin basic protein	Homo sapiens	18-41
22035235-4	2011	As a model study, maltose-binding protein (MBP) was dually labeled via incorporation of rho-azido-l-phenylalanine and cysteine at specific positions, immobilized on a surface, and subjected to smFRET analysis under native and denaturing conditions.	Cysteine	118-126	myelin basic protein	Homo sapiens	43-46
22038803-0	2011	Affinity and catalytic heterogeneity and metal-dependence of polyclonal myelin basic protein-hydrolyzing IgGs from sera of patients with systemic lupus erythematosus.	Metals	41-46	myelin basic protein	Homo sapiens	72-92
22038803-2	2011	Approximately 86% electrophoretically and immunologically homogeneous SLE immunoglobulin Gs (IgGs) purified using several affinity resins including Sepharose with immobilized hMBP specifically hydrolyze only hMBP but not many other tested proteins.	Sepharose	148-157	myelin basic protein	Homo sapiens	208-212
21659518-2	2011	Maltose-binding protein (MBP) is a large (a two-domain, 370-amino acid residue) bacterial periplasmic protein involved in maltose uptake.	Maltose	122-129	myelin basic protein	Homo sapiens	0-23
21659518-2	2011	Maltose-binding protein (MBP) is a large (a two-domain, 370-amino acid residue) bacterial periplasmic protein involved in maltose uptake.	Maltose	122-129	myelin basic protein	Homo sapiens	25-28
21659518-8	2011	In the case of maltose-bound MBP, the protein unfolds via the intermediate in 79% of the cases, the remaining 21% via path II.	Maltose	15-22	myelin basic protein	Homo sapiens	29-32
21898163-1	2011	The two new synthetic analogues of the MBP(83-99) epitope substituted at Lys(91) (primary TCR contact) with Phe [MBP(83-99) (Phe(91))] or Tyr [MBP(83-99) (Tyr(91))], have been structurally elucidated using 1D and 2D high resolution NMR studies.	Lysine	73-76	myelin basic protein	Homo sapiens	39-42
21898163-1	2011	The two new synthetic analogues of the MBP(83-99) epitope substituted at Lys(91) (primary TCR contact) with Phe [MBP(83-99) (Phe(91))] or Tyr [MBP(83-99) (Tyr(91))], have been structurally elucidated using 1D and 2D high resolution NMR studies.	Phenylalanine	108-111	myelin basic protein	Homo sapiens	39-42
21898163-1	2011	The two new synthetic analogues of the MBP(83-99) epitope substituted at Lys(91) (primary TCR contact) with Phe [MBP(83-99) (Phe(91))] or Tyr [MBP(83-99) (Tyr(91))], have been structurally elucidated using 1D and 2D high resolution NMR studies.	Phenylalanine	125-128	myelin basic protein	Homo sapiens	39-42
21242286-10	2011	A significant correlation was identified between MBP and (mean)Cho/Cr ratio.	Chromium	67-69	myelin basic protein	Homo sapiens	49-52
20641343-1	2004	(99m)Tc-DTPA-Mannosyl-dextran binds specifically to the macrophage mannose (mannose-fucose) receptors (MRCs) or mannose binding protein (MBP).	Technetium Tc 99m Pentetate	5-12	myelin basic protein	Homo sapiens	137-140
22096852-1	2011	OBJECTIVE: To explore the effects of n-hexane on expression of serum myelin proteins (MBP) in workers occupationally exposed to n-hexane.	n-hexane	37-45	myelin basic protein	Homo sapiens	86-89
22096852-1	2011	OBJECTIVE: To explore the effects of n-hexane on expression of serum myelin proteins (MBP) in workers occupationally exposed to n-hexane.	n-hexane	128-136	myelin basic protein	Homo sapiens	86-89
22096852-9	2011	Pearson correlation analysis showed the positive correlation between serum MBP levels and urinary 2,5-hexanedione levels (r = 0.781, P &lt; 0.01).	2,5-hexanedione	98-113	myelin basic protein	Homo sapiens	75-78
22096852-10	2011	CONCLUSION: The results of present study showed that the serum MBP levels of workers occupationally exposed to n-hexane significantly elevated, and the serum MBP can serve as the effective biomarker of n-hexane exposure.	n-hexane	111-119	myelin basic protein	Homo sapiens	63-66
22096852-10	2011	CONCLUSION: The results of present study showed that the serum MBP levels of workers occupationally exposed to n-hexane significantly elevated, and the serum MBP can serve as the effective biomarker of n-hexane exposure.	n-hexane	202-210	myelin basic protein	Homo sapiens	63-66
22096852-10	2011	CONCLUSION: The results of present study showed that the serum MBP levels of workers occupationally exposed to n-hexane significantly elevated, and the serum MBP can serve as the effective biomarker of n-hexane exposure.	n-hexane	202-210	myelin basic protein	Homo sapiens	158-161
21402396-1	2011	The 2,3,3",4,4",5,5"-heptachloro-1"-methyl-1,2"-bipyrrole (Q1, MBP-79) and further halogenated 1"-methyl-1,2"-bipyrroles (MBPs) are a class of marine natural products repeatedly detected in seafood and marine mammals from all over the world.	2,3,3",4,4",5,5"-heptachloro-1"-methyl-1,2"-bipyrrole	4-57	myelin basic protein	Homo sapiens	63-66
21402396-10	2011	A pure isolate of the major BrCl(6)-MBP (~1.5mg) was characterized by GC/MS and (13)C NMR to be 2-bromo-3,3",4,4",5,5"-hexachloro-1-methyl-1,2"-bipyrrole (Br-MBP-75).	Carbon-13	80-85	myelin basic protein	Homo sapiens	36-39
21402396-10	2011	A pure isolate of the major BrCl(6)-MBP (~1.5mg) was characterized by GC/MS and (13)C NMR to be 2-bromo-3,3",4,4",5,5"-hexachloro-1-methyl-1,2"-bipyrrole (Br-MBP-75).	2-bromo-3,3",4,4",5,5"-hexachloro-1-methyl-1,2"-bipyrrole	96-153	myelin basic protein	Homo sapiens	36-39
21402396-10	2011	A pure isolate of the major BrCl(6)-MBP (~1.5mg) was characterized by GC/MS and (13)C NMR to be 2-bromo-3,3",4,4",5,5"-hexachloro-1-methyl-1,2"-bipyrrole (Br-MBP-75).	2-bromo-3,3",4,4",5,5"-hexachloro-1-methyl-1,2"-bipyrrole	96-153	myelin basic protein	Homo sapiens	158-161
21402396-11	2011	Partial GC enantioseparation of the axially chiral Br-MBP-75 was achieved on a beta-PMCD column.	beta-pmcd	79-88	myelin basic protein	Homo sapiens	54-57
21402396-13	2011	Low amounts of pure BrCl(6)-MBP enantiomers could be trapped.	bromine chloride	20-24	myelin basic protein	Homo sapiens	28-31
20878261-8	2011	Phosphorylation of MBP-30aa was observed on a protein chip, and this phosphorylation was inhibited by the PKC inhibitor (GF109203X).	bisindolylmaleimide I	121-130	myelin basic protein	Homo sapiens	19-22
21696706-9	2011	Ibuprofen treatment also prevented the HI-induced loss O4- and O1-positive oligodendrocyte progenitor cells and myelin basic protein (MBP)-positive myelin content one week after P3 HI.	Ibuprofen	0-9	myelin basic protein	Homo sapiens	112-132
21696706-9	2011	Ibuprofen treatment also prevented the HI-induced loss O4- and O1-positive oligodendrocyte progenitor cells and myelin basic protein (MBP)-positive myelin content one week after P3 HI.	Ibuprofen	0-9	myelin basic protein	Homo sapiens	134-137
21420935-5	2011	To better understand structural and multifunctional roles of the PRR-IC, we report the crystal structure of the PRR-IC domain as maltose-binding protein (MBP) fusion proteins at 2.0A (maltose-free) and 2.15A (maltose-bound).	Maltose	129-136	myelin basic protein	Homo sapiens	154-157
21420935-5	2011	To better understand structural and multifunctional roles of the PRR-IC, we report the crystal structure of the PRR-IC domain as maltose-binding protein (MBP) fusion proteins at 2.0A (maltose-free) and 2.15A (maltose-bound).	Maltose	184-191	myelin basic protein	Homo sapiens	154-157
21312222-0	2011	Classical 18.5-and 21.5-kDa isoforms of myelin basic protein inhibit calcium influx into oligodendroglial cells, in contrast to golli isoforms.	Calcium	69-76	myelin basic protein	Homo sapiens	40-60
21378967-1	2011	We describe a phage display methodology for engineering synthetic antigen binders (sABs) that recognize either the apo or the ligand-bound conformation of maltose-binding protein (MBP).	sabs	83-87	myelin basic protein	Homo sapiens	155-178
21378967-1	2011	We describe a phage display methodology for engineering synthetic antigen binders (sABs) that recognize either the apo or the ligand-bound conformation of maltose-binding protein (MBP).	sabs	83-87	myelin basic protein	Homo sapiens	180-183
21378967-2	2011	sABs that preferentially recognize the maltose-bound form of MBP act as positive allosteric effectors by substantially increasing the affinity for maltose.	sabs	0-4	myelin basic protein	Homo sapiens	61-64
21378967-2	2011	sABs that preferentially recognize the maltose-bound form of MBP act as positive allosteric effectors by substantially increasing the affinity for maltose.	Maltose	39-46	myelin basic protein	Homo sapiens	61-64
21378967-2	2011	sABs that preferentially recognize the maltose-bound form of MBP act as positive allosteric effectors by substantially increasing the affinity for maltose.	Maltose	147-154	myelin basic protein	Homo sapiens	61-64
21378967-3	2011	A crystal structure of a sAB bound to the closed form of MBP reveals the basis for this allosteric effect.	sab	25-28	myelin basic protein	Homo sapiens	57-60
21378967-4	2011	We show that sABs that recognize the bound form of MBP can rescue the function of a binding-deficient mutant by restoring its natural affinity for maltose.	sabs	13-17	myelin basic protein	Homo sapiens	51-54
21378967-4	2011	We show that sABs that recognize the bound form of MBP can rescue the function of a binding-deficient mutant by restoring its natural affinity for maltose.	Maltose	147-154	myelin basic protein	Homo sapiens	51-54
20641343-1	2004	(99m)Tc-DTPA-Mannosyl-dextran binds specifically to the macrophage mannose (mannose-fucose) receptors (MRCs) or mannose binding protein (MBP).	mannosyl-dextran	13-29	myelin basic protein	Homo sapiens	137-140
21623415-5	2011	Beside acting as high-energy intermediates in the transfer of the phosphoryl group from donor to acceptor molecules, phosphohistidines have been found so far in histone H4, heterotrimeric G proteins, ion channel KCa3.1, annexin 1, P-selectin and myelin basic protein, as well as in recombinant thymidylate synthase expressed in bacterial cells.	phosphohistidine	117-134	myelin basic protein	Homo sapiens	246-266
21375947-3	2011	Maltose-binding-protein (MBP) NS3-4A fusion protein expression was induced by adding isopropyl-beta-D-thiogalacto-pyranoside (IPTG) and purified by affinity chromatography.	Isopropyl Thiogalactoside	85-124	myelin basic protein	Homo sapiens	0-23
21375947-3	2011	Maltose-binding-protein (MBP) NS3-4A fusion protein expression was induced by adding isopropyl-beta-D-thiogalacto-pyranoside (IPTG) and purified by affinity chromatography.	Isopropyl Thiogalactoside	85-124	myelin basic protein	Homo sapiens	25-28
21375947-3	2011	Maltose-binding-protein (MBP) NS3-4A fusion protein expression was induced by adding isopropyl-beta-D-thiogalacto-pyranoside (IPTG) and purified by affinity chromatography.	Isopropyl Thiogalactoside	126-130	myelin basic protein	Homo sapiens	0-23
21375947-3	2011	Maltose-binding-protein (MBP) NS3-4A fusion protein expression was induced by adding isopropyl-beta-D-thiogalacto-pyranoside (IPTG) and purified by affinity chromatography.	Isopropyl Thiogalactoside	126-130	myelin basic protein	Homo sapiens	25-28
21165562-3	2011	MBP, methyl CpG binding protein, suppresses transcription through binding to methylated CpG dinucleotides.	cytidylyl-3'-5'-guanosine	88-105	myelin basic protein	Homo sapiens	0-3
21623415-6	2011	Phosphoarginines occur in histone H3, myelin basic protein and capsidic protein VP12 of granulosis virus, whereas phospholysine in histone H1.	phospho-L-arginine	0-16	myelin basic protein	Homo sapiens	38-58
21510778-4	2011	CD4+IL-4+ cells were significantly increased in the presence of DMF and MHF when PBMCs were stimulated by MBP (P &lt; 0.003).	Dimethyl Fumarate	64-67	myelin basic protein	Homo sapiens	106-109
21510778-4	2011	CD4+IL-4+ cells were significantly increased in the presence of DMF and MHF when PBMCs were stimulated by MBP (P &lt; 0.003).	monomethyl fumarate	72-75	myelin basic protein	Homo sapiens	106-109
21510778-7	2011	Results of MBP stimulation in control group also showed a significant increase in CD4+IL-4+ cells in the presence of DMF and MHF.	Dimethyl Fumarate	117-120	myelin basic protein	Homo sapiens	11-14
21510778-7	2011	Results of MBP stimulation in control group also showed a significant increase in CD4+IL-4+ cells in the presence of DMF and MHF.	monomethyl fumarate	125-128	myelin basic protein	Homo sapiens	11-14
21647440-7	2011	Furthermore, using fluorescently labelled nucleotides, we observed binding of ATP and GTP, but not AMP, by MBP; the binding of nucleoside triphosphates was inhibited by the presence of CaM.	Adenosine Triphosphate	78-81	myelin basic protein	Homo sapiens	107-110
20978971-2	2011	MBP allows one to use a simple capture affinity step on amylose-agarose columns, resulting in a protein that is often 70-90% pure.	Amylose	56-63	myelin basic protein	Homo sapiens	0-3
20978971-2	2011	MBP allows one to use a simple capture affinity step on amylose-agarose columns, resulting in a protein that is often 70-90% pure.	Sepharose	64-71	myelin basic protein	Homo sapiens	0-3
22096548-5	2011	We have previously demonstrated that the non-homologous recombination of the genes encoding maltose binding protein (MBP) and TEM1 beta-lactamase (BLA) can result in fusion proteins in which beta-lactamase enzyme activity is allosterically regulated by maltose.	Maltose	92-99	myelin basic protein	Homo sapiens	117-120
21647440-7	2011	Furthermore, using fluorescently labelled nucleotides, we observed binding of ATP and GTP, but not AMP, by MBP; the binding of nucleoside triphosphates was inhibited by the presence of CaM.	Guanosine Triphosphate	86-89	myelin basic protein	Homo sapiens	107-110
21647440-7	2011	Furthermore, using fluorescently labelled nucleotides, we observed binding of ATP and GTP, but not AMP, by MBP; the binding of nucleoside triphosphates was inhibited by the presence of CaM.	nucleoside triphosphates	127-151	myelin basic protein	Homo sapiens	107-110
21055759-4	2010	The progress of batch and adsorptive detagging by DAPase of maltose binding protein (MBP) tagged with two variants of hexa-histidine fusion tag was successfully monitored using cationic exchange chromatography.	His-His-His-His-His-His	118-132	myelin basic protein	Homo sapiens	85-88
21822453-6	2010	Lack of dimerization in the MBP-SULT2A1 fusion protein decreased the K(d) for binding of DHEA at the allosteric site.	Dehydroepiandrosterone	89-93	myelin basic protein	Homo sapiens	28-31
20810540-8	2010	Oligomeric analysis of MBP-FMO3 also showed disassociation from a high-order oligomeric form to a monomeric status in the presence of Triton X-100.	Octoxynol	134-146	myelin basic protein	Homo sapiens	23-26
21822453-4	2010	The initial-rate parameters (K(m) and V(max)) of the monomer (MBP-SULT2A1) and native SULT2A1 dimer for DHEA sulfation are extremely similar; however, the monomer is not inhibited by DHEA.	Dehydroepiandrosterone	104-108	myelin basic protein	Homo sapiens	62-65
25961208-4	2010	The initial-rate parameters (Km and Vmax) of the monomer (MBP-SULT2A1) and native SULT2A1 dimer for DHEA sulfation are extremely similar; however, the monomer is not inhibited by DHEA.	Dehydroepiandrosterone	100-104	myelin basic protein	Homo sapiens	58-61
21822453-4	2010	The initial-rate parameters (K(m) and V(max)) of the monomer (MBP-SULT2A1) and native SULT2A1 dimer for DHEA sulfation are extremely similar; however, the monomer is not inhibited by DHEA.	Dehydroepiandrosterone	183-187	myelin basic protein	Homo sapiens	62-65
25961208-4	2010	The initial-rate parameters (Km and Vmax) of the monomer (MBP-SULT2A1) and native SULT2A1 dimer for DHEA sulfation are extremely similar; however, the monomer is not inhibited by DHEA.	Dehydroepiandrosterone	179-183	myelin basic protein	Homo sapiens	58-61
25961208-6	2010	Lack of dimerization in the MBP-SULT2A1 fusion protein decreased the Kd for binding of DHEA at the allosteric site.	Dehydroepiandrosterone	87-91	myelin basic protein	Homo sapiens	28-31
21339619-1	2010	The interaction of three proteins (histidine-containing phosphocarrier protein, HPr, calmodulin, CaM, and maltose binding protein, MBP) with synthetic silicon nitride (SiN(x)) membranes has been studied.	silicon nitride	151-166	myelin basic protein	Homo sapiens	131-134
21044600-0	2010	Copper uptake induces self-assembly of 18.5 kDa myelin basic protein (MBP).	Copper	0-6	myelin basic protein	Homo sapiens	48-68
20882567-12	2010	Mutation of Sp1 threonines 453 and 739, which are phosphorylated by ERK, decreased MBP transcriptional activity.	Threonine	16-26	myelin basic protein	Homo sapiens	83-86
21044600-0	2010	Copper uptake induces self-assembly of 18.5 kDa myelin basic protein (MBP).	Copper	0-6	myelin basic protein	Homo sapiens	70-73
21044600-2	2010	Furthermore, divalent transition metal ions, especially Zn(2+) and Cu(2+), seem to directly affect the MBP-mediated formation and stabilization of the myelin sheath of the central nervous system.	Metals	33-38	myelin basic protein	Homo sapiens	103-106
21044600-2	2010	Furthermore, divalent transition metal ions, especially Zn(2+) and Cu(2+), seem to directly affect the MBP-mediated formation and stabilization of the myelin sheath of the central nervous system.	Zinc	56-58	myelin basic protein	Homo sapiens	103-106
21044600-2	2010	Furthermore, divalent transition metal ions, especially Zn(2+) and Cu(2+), seem to directly affect the MBP-mediated formation and stabilization of the myelin sheath of the central nervous system.	Copper	67-69	myelin basic protein	Homo sapiens	103-106
21044600-4	2010	Here, using standard continuous wave and modern pulse electron paramagnetic resonance methods, as well as dynamic light scattering, we demonstrate the uptake and specific coordination of two Cu(2+) atoms or one Zn(2+) atom per MBP molecule in solution.	Copper	191-193	myelin basic protein	Homo sapiens	227-230
21044600-4	2010	Here, using standard continuous wave and modern pulse electron paramagnetic resonance methods, as well as dynamic light scattering, we demonstrate the uptake and specific coordination of two Cu(2+) atoms or one Zn(2+) atom per MBP molecule in solution.	Zinc	211-213	myelin basic protein	Homo sapiens	227-230
21044600-5	2010	In the presence of phosphates, further addition of divalent metal ions above a characteristic threshold of four Cu(2+) atoms or two Zn(2+) atoms per MBP molecule leads to the formation of large MBP aggregates within the protein solution.	Phosphates	19-29	myelin basic protein	Homo sapiens	149-152
21044600-5	2010	In the presence of phosphates, further addition of divalent metal ions above a characteristic threshold of four Cu(2+) atoms or two Zn(2+) atoms per MBP molecule leads to the formation of large MBP aggregates within the protein solution.	Phosphates	19-29	myelin basic protein	Homo sapiens	194-197
21044600-5	2010	In the presence of phosphates, further addition of divalent metal ions above a characteristic threshold of four Cu(2+) atoms or two Zn(2+) atoms per MBP molecule leads to the formation of large MBP aggregates within the protein solution.	Metals	60-65	myelin basic protein	Homo sapiens	149-152
21044600-5	2010	In the presence of phosphates, further addition of divalent metal ions above a characteristic threshold of four Cu(2+) atoms or two Zn(2+) atoms per MBP molecule leads to the formation of large MBP aggregates within the protein solution.	Metals	60-65	myelin basic protein	Homo sapiens	194-197
21044600-5	2010	In the presence of phosphates, further addition of divalent metal ions above a characteristic threshold of four Cu(2+) atoms or two Zn(2+) atoms per MBP molecule leads to the formation of large MBP aggregates within the protein solution.	cupric ion	112-118	myelin basic protein	Homo sapiens	194-197
21044600-5	2010	In the presence of phosphates, further addition of divalent metal ions above a characteristic threshold of four Cu(2+) atoms or two Zn(2+) atoms per MBP molecule leads to the formation of large MBP aggregates within the protein solution.	Zinc	132-134	myelin basic protein	Homo sapiens	149-152
21044600-5	2010	In the presence of phosphates, further addition of divalent metal ions above a characteristic threshold of four Cu(2+) atoms or two Zn(2+) atoms per MBP molecule leads to the formation of large MBP aggregates within the protein solution.	Zinc	132-134	myelin basic protein	Homo sapiens	194-197
20599634-2	2010	MBP is part of a noncovalent complex with a negatively charged, dye-labeled lipopeptide, (N-heptadecanoyl)-K(dye2)-linker-EEIYGEF-amide.	(n-heptadecanoyl)-k	89-108	myelin basic protein	Homo sapiens	0-3
20599634-2	2010	MBP is part of a noncovalent complex with a negatively charged, dye-labeled lipopeptide, (N-heptadecanoyl)-K(dye2)-linker-EEIYGEF-amide.	Amides	130-135	myelin basic protein	Homo sapiens	0-3
20599634-5	2010	We infer that the observed fluorescence increase on the addition of kinase and ATP is due to the phosphorylation of MBP, which decreases the affinity of MBP with the negatively charged, dye-labeled lipopeptide.	Adenosine Triphosphate	79-82	myelin basic protein	Homo sapiens	116-119
20599634-5	2010	We infer that the observed fluorescence increase on the addition of kinase and ATP is due to the phosphorylation of MBP, which decreases the affinity of MBP with the negatively charged, dye-labeled lipopeptide.	Adenosine Triphosphate	79-82	myelin basic protein	Homo sapiens	153-156
20854268-2	2010	We illustrate this approach by preparing maltose binding protein (MBP) wherein all eight tryptophan residues have been replaced with 6-fluorotryptophan at an incorporation level of 99.3%.	Tryptophan	89-99	myelin basic protein	Homo sapiens	41-64
20640959-2	2010	Recent notifications under the Rapid Alert System for Food and Feed have shown migration of 4-methylbenzophenone (4-MBP) from packaging into cereals.	4-methylbenzophenone	92-112	myelin basic protein	Homo sapiens	116-119
20854268-2	2010	We illustrate this approach by preparing maltose binding protein (MBP) wherein all eight tryptophan residues have been replaced with 6-fluorotryptophan at an incorporation level of 99.3%.	Tryptophan	89-99	myelin basic protein	Homo sapiens	66-69
20854268-2	2010	We illustrate this approach by preparing maltose binding protein (MBP) wherein all eight tryptophan residues have been replaced with 6-fluorotryptophan at an incorporation level of 99.3%.	6-fluorotryptophan	133-151	myelin basic protein	Homo sapiens	41-64
20854268-2	2010	We illustrate this approach by preparing maltose binding protein (MBP) wherein all eight tryptophan residues have been replaced with 6-fluorotryptophan at an incorporation level of 99.3%.	6-fluorotryptophan	133-151	myelin basic protein	Homo sapiens	66-69
19855925-2	2010	One of the best-characterized protein ligands for MBP is calmodulin (CaM), a highly acidic calcium sensor.	Calcium	91-98	myelin basic protein	Homo sapiens	50-53
21193873-13	2010	Docking studies demonstrated the interaction between HPbetaCD and bacterial maltose binding protein (MBP).	2-Hydroxypropyl-beta-cyclodextrin	53-61	myelin basic protein	Homo sapiens	76-99
21193873-13	2010	Docking studies demonstrated the interaction between HPbetaCD and bacterial maltose binding protein (MBP).	2-Hydroxypropyl-beta-cyclodextrin	53-61	myelin basic protein	Homo sapiens	101-104
20584760-7	2010	Several proteins altered by dieldrin are known to be associated with human neurodegenerative diseases, including apolipoprotein E, microtubule-associated tau protein, enolase 1, stathmin 1a, myelin basic protein, and parvalbumin.	Dieldrin	28-36	myelin basic protein	Homo sapiens	191-211
20593886-0	2010	Interaction of myelin basic protein with actin in the presence of dodecylphosphocholine micelles.	dodecylphosphocholine	66-87	myelin basic protein	Homo sapiens	15-35
20607863-4	2010	Inhibition of MK2 activity in oligodendrocyte progenitors (OLPs) using CMPD1 [4-(2"-fluorobiphenyl-4-yl)-N-(4-hydroxyphenyl)-butyramide] blocked the activation of MK2 and resulted in decreased accumulation of myelin-differentiation markers, including myelin-associated glycoprotein (MAG) and myelin basic protein (MBP).	4-(2"-fluorobiphenyl-4-yl)-n-(4-hydroxyphenyl)-butyramide	78-135	myelin basic protein	Homo sapiens	292-312
20603018-5	2010	Introducing two long-range disulfide bonds into DM-MBP reduces the entropic folding barrier of this intermediate and strongly accelerates native state formation.	Disulfides	27-36	myelin basic protein	Homo sapiens	51-54
20351655-5	2010	Myelin basic protein immunohistochemistry on P11 showed WM injury in LPS + HI group, but not in NS + HI, LPS, and NS groups.	hi	75-77	myelin basic protein	Homo sapiens	0-20
20205471-2	2010	In this study, we have demonstrated that phosphorylation of MBP and LRRKtide by the LRRK2 G2019S mutant was activated by Mn(2+) in vitro.	Manganese(2+)	121-127	myelin basic protein	Homo sapiens	60-63
20034108-1	2010	RG13 is a 72 kDa engineered allosteric enzyme comprised of a fusion between maltose binding protein (MBP) and TEM1 beta-lactamase (BLA) for which maltose is a positive effector of BLA activity.	Maltose	76-83	myelin basic protein	Homo sapiens	101-104
20172097-1	2010	Benzophenone (BP) and 4-methylbenzophenone (4MBP) are photo-initiators that are generally used to cure ink on carton boards.	4-methylbenzophenone	22-42	myelin basic protein	Homo sapiens	45-48
20147285-2	2010	To determine whether direct interactions between the translocated sugar and MalFGK(2) are important for the regulation of ATP hydrolysis, we used an MBP mutant (sMBP) that is able to bind either maltose or sucrose.	Sugars	66-71	myelin basic protein	Homo sapiens	149-152
20147285-2	2010	To determine whether direct interactions between the translocated sugar and MalFGK(2) are important for the regulation of ATP hydrolysis, we used an MBP mutant (sMBP) that is able to bind either maltose or sucrose.	Maltose	195-202	myelin basic protein	Homo sapiens	149-152
20147285-2	2010	To determine whether direct interactions between the translocated sugar and MalFGK(2) are important for the regulation of ATP hydrolysis, we used an MBP mutant (sMBP) that is able to bind either maltose or sucrose.	Sucrose	206-213	myelin basic protein	Homo sapiens	149-152
20147285-4	2010	Therefore, the ATPase activity of MalFGK(2) is coupled to translocation of maltose solely by interactions between MalFGK(2) and MBP.	Maltose	75-82	myelin basic protein	Homo sapiens	128-131
20147285-5	2010	For both maltose and sucrose, the ability of sMBP to stimulate the MalFGK(2) ATPase was greatly reduced compared with wild-type MBP, indicating that the mutations in sMBP have interfered with important interactions between MBP and MalFGK(2).	Maltose	9-16	myelin basic protein	Homo sapiens	46-49
20147285-5	2010	For both maltose and sucrose, the ability of sMBP to stimulate the MalFGK(2) ATPase was greatly reduced compared with wild-type MBP, indicating that the mutations in sMBP have interfered with important interactions between MBP and MalFGK(2).	Sucrose	21-28	myelin basic protein	Homo sapiens	46-49
20152420-1	2010	The guanidinium salt of the new heteropolymolybdate 11-molybdobismuthophosphate Gua(6)PBiMo(11)O(40) (11-MBP) was synthesized, characterized and used as a reagent for batch spectrophotometric (SP) and sequential injection determination of ascorbic acid (AsA).	guanidinium salt	4-20	myelin basic protein	Homo sapiens	105-108
20152420-1	2010	The guanidinium salt of the new heteropolymolybdate 11-molybdobismuthophosphate Gua(6)PBiMo(11)O(40) (11-MBP) was synthesized, characterized and used as a reagent for batch spectrophotometric (SP) and sequential injection determination of ascorbic acid (AsA).	heteropolymolybdate 11-molybdobismuthophosphate	32-79	myelin basic protein	Homo sapiens	105-108
20152420-1	2010	The guanidinium salt of the new heteropolymolybdate 11-molybdobismuthophosphate Gua(6)PBiMo(11)O(40) (11-MBP) was synthesized, characterized and used as a reagent for batch spectrophotometric (SP) and sequential injection determination of ascorbic acid (AsA).	gua(6)pbimo(11	80-94	myelin basic protein	Homo sapiens	105-108
20152420-2	2010	When compared to other Keggin"s heteropolyanions, the reduction of 11-MBP with AsA is both fast and maximal within a pH range of 1.6-2.0.	Ascorbic Acid	79-82	myelin basic protein	Homo sapiens	70-73
19785040-1	2010	This study describes the use of a hexa-histidine tagged exopeptidase for the cleavage of hexa-histidine tags from recombinant maltose binding protein (MBP) when both tagged species are bound to an immobilized metal affinity chromatography (IMAC) matrix.	His-His-His-His-His-His	34-48	myelin basic protein	Homo sapiens	151-154
20228945-2	2010	In this study, cyanylated cysteine is introduced at selected sites in two model peptides that have been shown to bind to membrane interfaces: a membrane-binding sequence of the human myelin basic protein and the antimicrobial peptide CM15.	Cysteine	26-34	myelin basic protein	Homo sapiens	183-203
19914203-1	2010	It was previously shown that myelin basic protein (MBP) can induce phase segregation in whole myelin monolayers and myelin lipid films, which leads to the accumulation of proteins into a separate phase, segregated from a cholesterol-enriched lipid phase.	Cholesterol	221-232	myelin basic protein	Homo sapiens	29-49
19914203-1	2010	It was previously shown that myelin basic protein (MBP) can induce phase segregation in whole myelin monolayers and myelin lipid films, which leads to the accumulation of proteins into a separate phase, segregated from a cholesterol-enriched lipid phase.	Cholesterol	221-232	myelin basic protein	Homo sapiens	51-54
19914203-2	2010	In this work we investigated some factors regulating the phase segregation induced by MBP using fluorescent microscopy of monolayers formed with binary and ternary lipid mixtures of dihydrocholesterol (a less-oxidable cholesterol analog) and phospholipids.	Cholestanol	182-200	myelin basic protein	Homo sapiens	86-89
19914203-2	2010	In this work we investigated some factors regulating the phase segregation induced by MBP using fluorescent microscopy of monolayers formed with binary and ternary lipid mixtures of dihydrocholesterol (a less-oxidable cholesterol analog) and phospholipids.	Cholesterol	189-200	myelin basic protein	Homo sapiens	86-89
19914203-2	2010	In this work we investigated some factors regulating the phase segregation induced by MBP using fluorescent microscopy of monolayers formed with binary and ternary lipid mixtures of dihydrocholesterol (a less-oxidable cholesterol analog) and phospholipids.	Phospholipids	242-255	myelin basic protein	Homo sapiens	86-89
19914203-4	2010	Our results show that MBP can induce a dihydrocholesterol-dependent segregation of phases that can be further regulated by the electrolyte concentration in the subphase and the composition (type and proportion) of non-sterol lipids.	Cholestanol	39-57	myelin basic protein	Homo sapiens	22-25
19914203-4	2010	Our results show that MBP can induce a dihydrocholesterol-dependent segregation of phases that can be further regulated by the electrolyte concentration in the subphase and the composition (type and proportion) of non-sterol lipids.	sterol lipids	218-231	myelin basic protein	Homo sapiens	22-25
20005986-7	2010	Very low doses of rotenone that did not affect viability or ATP synthesis still inhibited differentiation, as measured by reduced levels of the myelin transcripts 2",3"-Cyclic Nucleotide-3"-Phosphodiesterase and Myelin Basic Protein.	Rotenone	18-26	myelin basic protein	Homo sapiens	212-232
20083653-11	2010	Finally, we demonstrate that NO inhibited the expression of Foxp3 in MBP-primed T cells via soluble guanylyl cyclase-mediated production of cGMP.	Cyclic GMP	140-144	myelin basic protein	Homo sapiens	69-72
19468823-3	2010	In this study, the solution structural motif of MBP(83-99) has been performed using 2D (1)H-NMR spectroscopy in dimethyl sulfoxide.	Dimethyl Sulfoxide	112-130	myelin basic protein	Homo sapiens	48-51
19438809-5	2010	IgGs of all four sub-classes were catalytically active, with their contribution to the total activity of Abzs in the hydrolysis of hMBP and its 19-mer oligopeptide increasing in the order: IgG1 (1.5-2.1%) &lt; IgG2 (4.9-12.8%) &lt; IgG3 (14.7-25.0%) &lt; IgG4 (71-78%).	abzs	105-109	myelin basic protein	Homo sapiens	131-135
20083653-0	2010	Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide.	Nitric Oxide	76-88	myelin basic protein	Homo sapiens	0-20
19785040-1	2010	This study describes the use of a hexa-histidine tagged exopeptidase for the cleavage of hexa-histidine tags from recombinant maltose binding protein (MBP) when both tagged species are bound to an immobilized metal affinity chromatography (IMAC) matrix.	Metals	209-214	myelin basic protein	Homo sapiens	151-154
19785040-4	2010	In the presence of 50 mM imidazole, 46% of the originally adsorbed hexa-histidine tagged MBP was cleaved, released from the column, and recovered in a sample containing 100% native (i.e., completely detagged) MBP.	imidazole	25-34	myelin basic protein	Homo sapiens	89-92
19785040-4	2010	In the presence of 50 mM imidazole, 46% of the originally adsorbed hexa-histidine tagged MBP was cleaved, released from the column, and recovered in a sample containing 100% native (i.e., completely detagged) MBP.	imidazole	25-34	myelin basic protein	Homo sapiens	209-212
19785040-4	2010	In the presence of 50 mM imidazole, 46% of the originally adsorbed hexa-histidine tagged MBP was cleaved, released from the column, and recovered in a sample containing 100% native (i.e., completely detagged) MBP.	His-His-His-His-His-His	67-81	myelin basic protein	Homo sapiens	89-92
19785040-4	2010	In the presence of 50 mM imidazole, 46% of the originally adsorbed hexa-histidine tagged MBP was cleaved, released from the column, and recovered in a sample containing 100% native (i.e., completely detagged) MBP.	His-His-His-His-His-His	67-81	myelin basic protein	Homo sapiens	209-212
19785040-6	2010	At higher imidazole concentrations, binding of both hexa-histidine tagged MBP and DAPase to the column was minimized, leading to characteristics of cleavage more closely resembling that of a batch cleavage.	imidazole	10-19	myelin basic protein	Homo sapiens	74-77
19785040-6	2010	At higher imidazole concentrations, binding of both hexa-histidine tagged MBP and DAPase to the column was minimized, leading to characteristics of cleavage more closely resembling that of a batch cleavage.	His-His-His-His-His-His	52-66	myelin basic protein	Homo sapiens	74-77
19854616-7	2009	In the LEV group, only 2 of the 50 patients (4%) had &gt;10 mmHg decrease in their MBP.	Levetiracetam	7-10	myelin basic protein	Homo sapiens	83-86
20004340-4	2009	Central glial-4 OLG progenitors were induced to differentiate in the absence and presence of 100 mM ethanol, and ethanol-caused changes in the levels of c-Fos and myelin basic protein (MBP) were determined by Western blot analysis at selected developmental stages.	Ethanol	113-120	myelin basic protein	Homo sapiens	163-183
20004340-4	2009	Central glial-4 OLG progenitors were induced to differentiate in the absence and presence of 100 mM ethanol, and ethanol-caused changes in the levels of c-Fos and myelin basic protein (MBP) were determined by Western blot analysis at selected developmental stages.	Ethanol	113-120	myelin basic protein	Homo sapiens	185-188
20004340-7	2009	Ethanol also decreased the rate of the burst of MBP expression that occurred between 1 and 2 DoD, reducing the MBP level by 47% at 2 DoD.	Ethanol	0-7	myelin basic protein	Homo sapiens	48-51
20004340-7	2009	Ethanol also decreased the rate of the burst of MBP expression that occurred between 1 and 2 DoD, reducing the MBP level by 47% at 2 DoD.	Ethanol	0-7	myelin basic protein	Homo sapiens	111-114
20004340-8	2009	The ethanol-caused delays of c-Fos downregulation and MBP upregulation were both blocked by the protein kinase C (PKC) inhibitor bisindolylmaleimide I (BIM).	Ethanol	4-11	myelin basic protein	Homo sapiens	54-57
20004340-8	2009	The ethanol-caused delays of c-Fos downregulation and MBP upregulation were both blocked by the protein kinase C (PKC) inhibitor bisindolylmaleimide I (BIM).	bisindolylmaleimide I	129-150	myelin basic protein	Homo sapiens	54-57
20004340-8	2009	The ethanol-caused delays of c-Fos downregulation and MBP upregulation were both blocked by the protein kinase C (PKC) inhibitor bisindolylmaleimide I (BIM).	bisindolylmaleimide I	152-155	myelin basic protein	Homo sapiens	54-57
20004340-10	2009	The results indicate that ethanol-caused delays of the stage-specific c-Fos downregulation and the inhibition of MBP expression both occur through a PKC-mediated mechanism.	Ethanol	26-33	myelin basic protein	Homo sapiens	113-116
19856323-8	2010	The obtained results indicated that the co-expression of the recombinant protein and caseins by the mammary gland along with the recombinant protein"s ability to form calcium bridges played a key role in the association of the recombinant human myelin basic protein (rhMBP) with the casein micelles of milk.	Calcium	167-174	myelin basic protein	Homo sapiens	245-265
20004340-0	2009	Ethanol alters the expressions of c-Fos and myelin basic protein in differentiating oligodendrocytes.	Ethanol	0-7	myelin basic protein	Homo sapiens	44-64
19733183-6	2009	MBP consists of two lobes connected by a hinge region that move from an open to a closed conformation when the ligand maltose binds.	Maltose	118-125	myelin basic protein	Homo sapiens	0-3
19615435-3	2009	Comparison of the in vitro neurotoxicity data with general cytotoxicity data generated in a non-neuronal cell line and with in vivo data such as acute human lethal blood concentration, revealed that GABA(A) receptor function, acetylcholine esterase activity, cell membrane potential, glucose uptake, total RNA expression and altered gene expression of NF-H, GFAP, MBP, HSP32 and caspase-3 were the best endpoints to use for further testing with 36 additional chemicals.	gamma-Aminobutyric Acid	199-203	myelin basic protein	Homo sapiens	364-367
19692707-5	2009	MBP possesses endogenous serine proteinase activity and can undergo autocatalytic cleavage liberating distinct fragments.	Serine	25-31	myelin basic protein	Homo sapiens	0-3
19579010-2	2009	The amount of immobilized MBP-vascular endothelial growth factors (VEGFs) for polystyrene surface was increased with respect to increasing protein, showing 1019 ng/cm(2) at 100 microg protein/ml.	Polystyrenes	78-89	myelin basic protein	Homo sapiens	26-29
19806747-1	2009	The emission of arsenic (As) with leachate from mechanically biologically pretreated municipal solid waste (MBP-MSW) was quantified over one year using landfill simulation reactors.	Arsenic	16-23	myelin basic protein	Homo sapiens	108-111
19806747-1	2009	The emission of arsenic (As) with leachate from mechanically biologically pretreated municipal solid waste (MBP-MSW) was quantified over one year using landfill simulation reactors.	Arsenic	25-27	myelin basic protein	Homo sapiens	108-111
19928688-12	2009	After administering intravenous high-dose methylprednisolone (1,000 mg/day for 3 days), her symptoms markedly improved with normalization of myelin basic protein.	Methylprednisolone	42-60	myelin basic protein	Homo sapiens	141-161
19630440-1	2009	ATP hydrolysis by the maltose transporter (MalFGK(2)) is regulated by maltose binding protein (MBP).	Adenosine Triphosphate	0-3	myelin basic protein	Homo sapiens	70-93
19630440-1	2009	ATP hydrolysis by the maltose transporter (MalFGK(2)) is regulated by maltose binding protein (MBP).	Adenosine Triphosphate	0-3	myelin basic protein	Homo sapiens	95-98
19630440-2	2009	Binding of maltose to MBP brings about a conformational change from open to closed that leads to a strong stimulation of the MalFGK(2) ATPase.	Maltose	11-18	myelin basic protein	Homo sapiens	22-25
19630440-6	2009	The effect of MBP concentration on the stimulation of MalFGK(2) was assessed: for unliganded MBP, the apparent K(M) for stimulation of MalFGK(2) was below 1 microM, while for maltose-bound MBP, the K(M) was approximately 15 microM.	Maltose	175-182	myelin basic protein	Homo sapiens	14-17
19682975-3	2009	To the best of our knowledge, this is the first report to provide information regarding the biological distance between the two lobes of MBP upon maltose binding.	Maltose	146-153	myelin basic protein	Homo sapiens	137-140
19682975-5	2009	After the FRET reaction, maltose-treated MBP was shown to exhibit a considerable energy transfer (FRET efficiency (E)= approximately 0.11, Distance (D)= approximately 6.93 nm) at the ensemble level, which was regarded as reflective of the increase in donor quenching and the upshift in acceptor emission intensity, thereby suggesting that the donor and the acceptor had been brought close together as the result of structural alterations in MBP.	Maltose	25-32	myelin basic protein	Homo sapiens	41-44
19682975-5	2009	After the FRET reaction, maltose-treated MBP was shown to exhibit a considerable energy transfer (FRET efficiency (E)= approximately 0.11, Distance (D)= approximately 6.93 nm) at the ensemble level, which was regarded as reflective of the increase in donor quenching and the upshift in acceptor emission intensity, thereby suggesting that the donor and the acceptor had been brought close together as the result of structural alterations in MBP.	Maltose	25-32	myelin basic protein	Homo sapiens	441-444
19682975-6	2009	However, upon glucose treatment, no FRET phenomenon was detected, thereby implying the specificity of interaction between MBP and maltose.	Maltose	130-137	myelin basic protein	Homo sapiens	122-125
19682975-8	2009	Therefore, our data showed that maltose-stimulated conformational changes of MBP could be measured by FRET, thereby providing biological information, including the FRET efficiency and the intramolecular distance.	Maltose	32-39	myelin basic protein	Homo sapiens	77-80
19640876-2	2009	The availability of both hydrogenated and perdeuterated samples of maltose-binding protein (MBP) allowed us to directly measure with great accuracy the signal from the protein and the hydration water alone.	Water	194-199	myelin basic protein	Homo sapiens	67-90
19640876-2	2009	The availability of both hydrogenated and perdeuterated samples of maltose-binding protein (MBP) allowed us to directly measure with great accuracy the signal from the protein and the hydration water alone.	Water	194-199	myelin basic protein	Homo sapiens	92-95
19640876-5	2009	In MBP and its hydration water, the two relaxations take place with similar average characteristic times of approximately 10 and 0.2 ps.	Water	25-30	myelin basic protein	Homo sapiens	3-6
19465640-5	2009	In this study, we show that MBP can bind DNA and RNA in a calcium-dependent manner from a variety of origins, including bacteria, plasmids, synthetic oligonucleotides, and fragmented DNA of apoptotic cells.	Calcium	58-65	myelin basic protein	Homo sapiens	28-31
19465640-5	2009	In this study, we show that MBP can bind DNA and RNA in a calcium-dependent manner from a variety of origins, including bacteria, plasmids, synthetic oligonucleotides, and fragmented DNA of apoptotic cells.	Oligonucleotides	150-166	myelin basic protein	Homo sapiens	28-31
19950581-9	2009	MTT measures of pSVCEP-MBP-CAT transfected group showed increased proliferation and anti-apoptosis.	monooxyethylene trimethylolpropane tristearate	0-3	myelin basic protein	Homo sapiens	23-26
19649992-0	2009	BHT-3009, a myelin basic protein-encoding plasmid for the treatment of multiple sclerosis.	Butylated Hydroxytoluene	0-3	myelin basic protein	Homo sapiens	12-32
19649992-6	2009	Bayhill Therapeutic Inc"s BHT-3009 encodes full-length, human myelin basic protein (MBP), and has recently been evaluated in a phase I/II and a phase II clinical trial.	Butylated Hydroxytoluene	26-29	myelin basic protein	Homo sapiens	62-82
19649992-6	2009	Bayhill Therapeutic Inc"s BHT-3009 encodes full-length, human myelin basic protein (MBP), and has recently been evaluated in a phase I/II and a phase II clinical trial.	Butylated Hydroxytoluene	26-29	myelin basic protein	Homo sapiens	84-87
19649992-7	2009	BHT-3009 was safe and well tolerated in both trials, inducing immune tolerance that extended beyond MBP to other myelin antigens.	Butylated Hydroxytoluene	0-3	myelin basic protein	Homo sapiens	100-103
19296044-10	2009	Serum cross-linked N-teleopeptides of type-I collagen (NTx) in MBP group at 8 months and in whole milk group at 6 months were significantly decreased from baseline.	Nitrogen	19-20	myelin basic protein	Homo sapiens	63-66
19527025-3	2009	A cytochrome cb(562) variant, MBP-Phen1, which features a covalently attached phenanthroline (Phen) group on its surface, self-assembles into an unusual triangular architecture (Ni(3):MBP-Phen1(3)) upon binding Ni as a result of specific Phen-protein interactions.	Phenanthrolines	78-92	myelin basic protein	Homo sapiens	30-33
19527025-3	2009	A cytochrome cb(562) variant, MBP-Phen1, which features a covalently attached phenanthroline (Phen) group on its surface, self-assembles into an unusual triangular architecture (Ni(3):MBP-Phen1(3)) upon binding Ni as a result of specific Phen-protein interactions.	Phenanthrolines	34-38	myelin basic protein	Homo sapiens	30-33
19527025-3	2009	A cytochrome cb(562) variant, MBP-Phen1, which features a covalently attached phenanthroline (Phen) group on its surface, self-assembles into an unusual triangular architecture (Ni(3):MBP-Phen1(3)) upon binding Ni as a result of specific Phen-protein interactions.	Phenanthrolines	34-38	myelin basic protein	Homo sapiens	184-187
19559391-6	2009	This remodeling of NaChs included prominent NaCh expression within nerve regions that showed a selective loss of MBP staining in a pattern consistent with a demyelinating process.	nach	19-23	myelin basic protein	Homo sapiens	113-116
19494180-6	2009	mGene.web is available at http://www.mgene.org/web, it is free of charge and can be used for eukaryotic genomes of small to moderate size (several hundred Mbp).	mgene	0-5	myelin basic protein	Homo sapiens	155-158
19494180-6	2009	mGene.web is available at http://www.mgene.org/web, it is free of charge and can be used for eukaryotic genomes of small to moderate size (several hundred Mbp).	mgene	37-42	myelin basic protein	Homo sapiens	155-158
19848249-5	2009	RESULTS: The total number of MBP+ cells, GR+ cells, and MBP+/GR+ cells in the CS/asthma group was significantly higher than that in the other two groups.	Cesium	78-80	myelin basic protein	Homo sapiens	56-59
19848249-6	2009	The total number of these cells in the CS/AR group was also higher than that in the CS only group The ratio of MBP+/GR+ cells to GR+ cells was highest in the CS/asthma group.	Cesium	39-41	myelin basic protein	Homo sapiens	111-114
19848249-6	2009	The total number of these cells in the CS/AR group was also higher than that in the CS only group The ratio of MBP+/GR+ cells to GR+ cells was highest in the CS/asthma group.	Argon	42-44	myelin basic protein	Homo sapiens	111-114
19848249-7	2009	The ratio of MBP+/GR+ cells to MBP+ cells in the CS only group was lower than those in the other two groups.	Cesium	49-51	myelin basic protein	Homo sapiens	13-16
19848249-7	2009	The ratio of MBP+/GR+ cells to MBP+ cells in the CS only group was lower than those in the other two groups.	Cesium	49-51	myelin basic protein	Homo sapiens	31-34
19692707-10	2009	MBP-mediated Abeta degradation is inhibited by serine proteinase inhibitors.	Serine	47-53	myelin basic protein	Homo sapiens	0-3
19352009-4	2009	MBP-hPDE4B2 after amylose-resin chromatography showed 35% homogeneity, and its Michaelis-Menten constant was 10+/-2 microM (n=3).	Amylose	18-25	myelin basic protein	Homo sapiens	0-3
19129245-1	2009	The serum mannan-binding protein (MBP) is a host defense C-type lectin specific for mannose, N-acetylglucosamine, and fucose residues, and exhibits growth inhibitory activity toward human colorectal carcinoma cells.	Mannose	84-91	myelin basic protein	Homo sapiens	10-32
19301314-4	2009	BODIPY-FL-aminophenylalanine was incorporated in place of 15 tyrosines, as well as the N-terminal Lys1, and the C-terminal Lys370 of MBP.	bodipy-fl-aminophenylalanine	0-28	myelin basic protein	Homo sapiens	133-136
19301314-5	2009	Fluorescence measurements revealed that MBP containing a BODIPY-FL moiety in place of Tyr210 showed a 13-fold increase in fluorescence upon binding of maltose.	bodipy-fl	57-66	myelin basic protein	Homo sapiens	40-43
19301314-5	2009	Fluorescence measurements revealed that MBP containing a BODIPY-FL moiety in place of Tyr210 showed a 13-fold increase in fluorescence upon binding of maltose.	Maltose	151-158	myelin basic protein	Homo sapiens	40-43
19301314-7	2009	MBP containing a BODIPY-558 moiety also showed a maltose-dependent increase in fluorescence.	Maltose	49-56	myelin basic protein	Homo sapiens	0-3
19129245-0	2009	Highly fucosylated N-glycan ligands for mannan-binding protein expressed specifically on CD26 (DPPVI) isolated from a human colorectal carcinoma cell line, SW1116.	n-glycan	19-27	myelin basic protein	Homo sapiens	40-62
19129245-1	2009	The serum mannan-binding protein (MBP) is a host defense C-type lectin specific for mannose, N-acetylglucosamine, and fucose residues, and exhibits growth inhibitory activity toward human colorectal carcinoma cells.	Mannose	84-91	myelin basic protein	Homo sapiens	34-37
19129245-1	2009	The serum mannan-binding protein (MBP) is a host defense C-type lectin specific for mannose, N-acetylglucosamine, and fucose residues, and exhibits growth inhibitory activity toward human colorectal carcinoma cells.	Acetylglucosamine	93-112	myelin basic protein	Homo sapiens	10-32
19129245-1	2009	The serum mannan-binding protein (MBP) is a host defense C-type lectin specific for mannose, N-acetylglucosamine, and fucose residues, and exhibits growth inhibitory activity toward human colorectal carcinoma cells.	Acetylglucosamine	93-112	myelin basic protein	Homo sapiens	34-37
19129245-1	2009	The serum mannan-binding protein (MBP) is a host defense C-type lectin specific for mannose, N-acetylglucosamine, and fucose residues, and exhibits growth inhibitory activity toward human colorectal carcinoma cells.	Fucose	118-124	myelin basic protein	Homo sapiens	10-32
19129245-1	2009	The serum mannan-binding protein (MBP) is a host defense C-type lectin specific for mannose, N-acetylglucosamine, and fucose residues, and exhibits growth inhibitory activity toward human colorectal carcinoma cells.	Fucose	118-124	myelin basic protein	Homo sapiens	34-37
19129245-2	2009	The MBP-ligand oligosaccharides (MLO) isolated from a human colorectal carcinoma cell line, SW1116, are large, multiantennary N-glycans with highly fucosylated polylactosamine-type structures having Le(b)-Le(a) or tandem repeats of the Le(a) structure at their nonreducing ends.	Oligosaccharides	15-31	myelin basic protein	Homo sapiens	4-7
19129245-2	2009	The MBP-ligand oligosaccharides (MLO) isolated from a human colorectal carcinoma cell line, SW1116, are large, multiantennary N-glycans with highly fucosylated polylactosamine-type structures having Le(b)-Le(a) or tandem repeats of the Le(a) structure at their nonreducing ends.	n-glycans	126-135	myelin basic protein	Homo sapiens	4-7
19129245-2	2009	The MBP-ligand oligosaccharides (MLO) isolated from a human colorectal carcinoma cell line, SW1116, are large, multiantennary N-glycans with highly fucosylated polylactosamine-type structures having Le(b)-Le(a) or tandem repeats of the Le(a) structure at their nonreducing ends.	polylactosamine	160-175	myelin basic protein	Homo sapiens	4-7
19129245-4	2009	Glycosidase digestion revealed that CD26 contained such complex-type N-glycans that appear to mediate the MBP binding.	n-glycans	69-78	myelin basic protein	Homo sapiens	106-109
19129245-6	2009	More interestingly, a comparison of the N-glycans released from the MBP-binding and non-MBP-binding glycopeptides suggested that complex-type N-glycans carrying a minimum of 4 Le(a)/Le(b) epitopes arranged either as multimeric tandem repeats or terminal epitopes on multiantennary structures are critically important for the high affinity binding to MBP.	n-glycans	40-49	myelin basic protein	Homo sapiens	68-71
19129245-6	2009	More interestingly, a comparison of the N-glycans released from the MBP-binding and non-MBP-binding glycopeptides suggested that complex-type N-glycans carrying a minimum of 4 Le(a)/Le(b) epitopes arranged either as multimeric tandem repeats or terminal epitopes on multiantennary structures are critically important for the high affinity binding to MBP.	n-glycans	40-49	myelin basic protein	Homo sapiens	88-91
19129245-6	2009	More interestingly, a comparison of the N-glycans released from the MBP-binding and non-MBP-binding glycopeptides suggested that complex-type N-glycans carrying a minimum of 4 Le(a)/Le(b) epitopes arranged either as multimeric tandem repeats or terminal epitopes on multiantennary structures are critically important for the high affinity binding to MBP.	n-glycans	40-49	myelin basic protein	Homo sapiens	88-91
19129245-6	2009	More interestingly, a comparison of the N-glycans released from the MBP-binding and non-MBP-binding glycopeptides suggested that complex-type N-glycans carrying a minimum of 4 Le(a)/Le(b) epitopes arranged either as multimeric tandem repeats or terminal epitopes on multiantennary structures are critically important for the high affinity binding to MBP.	Glycopeptides	100-113	myelin basic protein	Homo sapiens	88-91
19129245-6	2009	More interestingly, a comparison of the N-glycans released from the MBP-binding and non-MBP-binding glycopeptides suggested that complex-type N-glycans carrying a minimum of 4 Le(a)/Le(b) epitopes arranged either as multimeric tandem repeats or terminal epitopes on multiantennary structures are critically important for the high affinity binding to MBP.	Glycopeptides	100-113	myelin basic protein	Homo sapiens	88-91
19129245-6	2009	More interestingly, a comparison of the N-glycans released from the MBP-binding and non-MBP-binding glycopeptides suggested that complex-type N-glycans carrying a minimum of 4 Le(a)/Le(b) epitopes arranged either as multimeric tandem repeats or terminal epitopes on multiantennary structures are critically important for the high affinity binding to MBP.	n-glycans	142-151	myelin basic protein	Homo sapiens	68-71
19129245-6	2009	More interestingly, a comparison of the N-glycans released from the MBP-binding and non-MBP-binding glycopeptides suggested that complex-type N-glycans carrying a minimum of 4 Le(a)/Le(b) epitopes arranged either as multimeric tandem repeats or terminal epitopes on multiantennary structures are critically important for the high affinity binding to MBP.	n-glycans	142-151	myelin basic protein	Homo sapiens	88-91
19129245-6	2009	More interestingly, a comparison of the N-glycans released from the MBP-binding and non-MBP-binding glycopeptides suggested that complex-type N-glycans carrying a minimum of 4 Le(a)/Le(b) epitopes arranged either as multimeric tandem repeats or terminal epitopes on multiantennary structures are critically important for the high affinity binding to MBP.	n-glycans	142-151	myelin basic protein	Homo sapiens	88-91
19129245-8	2009	Finally, hypothetical 3D models of tandem repeats of the Le(a) epitope and the MBP-Lewis oligosaccharide complex were presented.	Oligosaccharides	89-104	myelin basic protein	Homo sapiens	79-82
19218452-1	2009	Force-distance measurements between supported lipid bilayers mimicking the cytoplasmic surface of myelin at various surface coverages of myelin basic protein (MBP) indicate that maximum adhesion and minimum cytoplasmic spacing occur when each negative lipid in the membrane can bind to a positive arginine or lysine group on MBP.	Arginine	297-305	myelin basic protein	Homo sapiens	137-157
19217266-5	2009	On histology, significant increase in neurofilament expression (125%) and decrease in myelin basic protein (40%) were observed in the same region in cocaine-treated animals.	Cocaine	149-156	myelin basic protein	Homo sapiens	86-106
19178193-1	2009	Myelin basic protein (MBP) is a highly post-translationally modified, multifunctional structural component of central nervous system myelin, adhering to phospholipid membranes and assembling cytoskeletal proteins, and has previously been shown to bind SH3 domains in vitro and tether them to a membrane surface [Polverini, E., et al.	Phospholipids	153-165	myelin basic protein	Homo sapiens	0-20
19178193-1	2009	Myelin basic protein (MBP) is a highly post-translationally modified, multifunctional structural component of central nervous system myelin, adhering to phospholipid membranes and assembling cytoskeletal proteins, and has previously been shown to bind SH3 domains in vitro and tether them to a membrane surface [Polverini, E., et al.	Phospholipids	153-165	myelin basic protein	Homo sapiens	22-25
19178193-6	2009	Post-translational modifications of MBP which reduced its net positive charge, i.e., phosphorylation or arginine deimination, increased the degree of repulsion of Fyn-SH3 from the membrane surface, an effect further modulated by the lipid charge.	Arginine	104-112	myelin basic protein	Homo sapiens	36-39
19120069-8	2009	Furthermore, we have shown that the pro-angiogenic effect of MBP is not due to its cationic charge since stimulation of the CAMs with the synthetic polycation, poly-L-arginine does not induce any angiogenic effects.	polyarginine	160-175	myelin basic protein	Homo sapiens	61-64
19218452-1	2009	Force-distance measurements between supported lipid bilayers mimicking the cytoplasmic surface of myelin at various surface coverages of myelin basic protein (MBP) indicate that maximum adhesion and minimum cytoplasmic spacing occur when each negative lipid in the membrane can bind to a positive arginine or lysine group on MBP.	Arginine	297-305	myelin basic protein	Homo sapiens	159-162
19218452-1	2009	Force-distance measurements between supported lipid bilayers mimicking the cytoplasmic surface of myelin at various surface coverages of myelin basic protein (MBP) indicate that maximum adhesion and minimum cytoplasmic spacing occur when each negative lipid in the membrane can bind to a positive arginine or lysine group on MBP.	Lysine	309-315	myelin basic protein	Homo sapiens	137-157
19218452-1	2009	Force-distance measurements between supported lipid bilayers mimicking the cytoplasmic surface of myelin at various surface coverages of myelin basic protein (MBP) indicate that maximum adhesion and minimum cytoplasmic spacing occur when each negative lipid in the membrane can bind to a positive arginine or lysine group on MBP.	Lysine	309-315	myelin basic protein	Homo sapiens	159-162
19059402-0	2009	An ISFET biosensor for the monitoring of maltose-induced conformational changes in MBP.	Maltose	41-48	myelin basic protein	Homo sapiens	83-86
18814266-6	2009	Reduced MBP protein expression was confirmed by SDS-PAGE and Western blotting, and in situ hybridization experiments revealed that lovastatin blocks MBP mRNA transport into oligodendrocyte processes.	Sodium Dodecyl Sulfate	48-51	myelin basic protein	Homo sapiens	8-11
18814266-6	2009	Reduced MBP protein expression was confirmed by SDS-PAGE and Western blotting, and in situ hybridization experiments revealed that lovastatin blocks MBP mRNA transport into oligodendrocyte processes.	Lovastatin	131-141	myelin basic protein	Homo sapiens	8-11
18814266-6	2009	Reduced MBP protein expression was confirmed by SDS-PAGE and Western blotting, and in situ hybridization experiments revealed that lovastatin blocks MBP mRNA transport into oligodendrocyte processes.	Lovastatin	131-141	myelin basic protein	Homo sapiens	149-152
18845658-6	2009	Proton Density-weighted images of this formalin-fixed material were acquired at 4.7 Tesla before the tissue was sectioned and stained for Myelin Basic Protein.	Formaldehyde	39-47	myelin basic protein	Homo sapiens	138-158
19472237-2	2009	The conformational motion of H-MBP leads to the interlinking of the H-MBPs by an extended Cu-O network that is ferromagnetic, whereas the conformational freezing of the S-en-MBP leads to an ordered pairwise-stacked arrangement that is weakly antoferrimagnetic.	cu-o	90-94	myelin basic protein	Homo sapiens	31-34
19059402-1	2009	Here we describe an ion sensitive field effect transistor (ISFET) biosensor, which was designed to monitor directly the surface charge of structurally altered maltose binding protein (MBP) upon stimulation with maltose.	Maltose	159-166	myelin basic protein	Homo sapiens	184-187
19059402-4	2009	Collectively, our results clearly suggest that ISFET provide a high fidelity system for the detection of maltose-induced structural alterations in MBP.	Maltose	105-112	myelin basic protein	Homo sapiens	147-150
19432497-1	2009	Clodronic acid (Cl(2)-MBP [dichloromethylene bisphosphonic acid], clodronate) is a halogenated non-nitrogen-containing bisphosphonate with antiresorptive efficacy in a variety of diseases associated with excessive bone resorption.	Clodronic Acid	0-14	myelin basic protein	Homo sapiens	22-25
19134474-4	2009	FTIR spectroscopy of fully (13)C,(15)N-labeled MBP complexed with unlabeled F-actin showed induced folding of both protein partners, viz., some increase in beta-sheet content in actin, and increases in both alpha-helix and beta-sheet content in MBP, albeit with considerable extended structure remaining.	Nitrogen	37-38	myelin basic protein	Homo sapiens	47-50
19134474-4	2009	FTIR spectroscopy of fully (13)C,(15)N-labeled MBP complexed with unlabeled F-actin showed induced folding of both protein partners, viz., some increase in beta-sheet content in actin, and increases in both alpha-helix and beta-sheet content in MBP, albeit with considerable extended structure remaining.	Nitrogen	37-38	myelin basic protein	Homo sapiens	245-248
19432497-1	2009	Clodronic acid (Cl(2)-MBP [dichloromethylene bisphosphonic acid], clodronate) is a halogenated non-nitrogen-containing bisphosphonate with antiresorptive efficacy in a variety of diseases associated with excessive bone resorption.	Chlorine	16-21	myelin basic protein	Homo sapiens	22-25
19432497-1	2009	Clodronic acid (Cl(2)-MBP [dichloromethylene bisphosphonic acid], clodronate) is a halogenated non-nitrogen-containing bisphosphonate with antiresorptive efficacy in a variety of diseases associated with excessive bone resorption.	Clodronic Acid	66-76	myelin basic protein	Homo sapiens	22-25
19432497-1	2009	Clodronic acid (Cl(2)-MBP [dichloromethylene bisphosphonic acid], clodronate) is a halogenated non-nitrogen-containing bisphosphonate with antiresorptive efficacy in a variety of diseases associated with excessive bone resorption.	Nitrogen	99-107	myelin basic protein	Homo sapiens	22-25
19432497-1	2009	Clodronic acid (Cl(2)-MBP [dichloromethylene bisphosphonic acid], clodronate) is a halogenated non-nitrogen-containing bisphosphonate with antiresorptive efficacy in a variety of diseases associated with excessive bone resorption.	Clodronic Acid	27-63	myelin basic protein	Homo sapiens	22-25
19432497-1	2009	Clodronic acid (Cl(2)-MBP [dichloromethylene bisphosphonic acid], clodronate) is a halogenated non-nitrogen-containing bisphosphonate with antiresorptive efficacy in a variety of diseases associated with excessive bone resorption.	Diphosphonates	119-133	myelin basic protein	Homo sapiens	22-25
19855355-2	2009	The efficacy of intravenous choline citrate infusions was investigated in 34 patients with multiple sclerosis (MS) by clinical evaluation and by monitoring of lymphocyte proliferation in vitro against fragments of myelin basic protein (MOG-35-55, MBP15-31, PLP 39-15) over a period of 12 weeks.	Choline	28-43	myelin basic protein	Homo sapiens	214-234
19389514-2	2009	Presently, one of SLA-I gene SLA-2 and beta(2)m gene were expressed as soluble maltose binding proteins (MBP-proteins) in a pMAL-p2X/Escherichia coli TB1 system and identified by western blotting with anti-MBP polyclonal antibodies.	Maltose	79-86	myelin basic protein	Homo sapiens	105-108
18948697-5	2009	Mitoxantrone (MX) is a potent immunosuppressant for the treatment of active MS. We investigated the long-term effects of MX on the suppressive function of T(reg) after mitogen and myelin basic protein (MBP) stimulation in 20 MX-treated patients.	Mitoxantrone	0-12	myelin basic protein	Homo sapiens	180-200
18948697-5	2009	Mitoxantrone (MX) is a potent immunosuppressant for the treatment of active MS. We investigated the long-term effects of MX on the suppressive function of T(reg) after mitogen and myelin basic protein (MBP) stimulation in 20 MX-treated patients.	Mitoxantrone	0-12	myelin basic protein	Homo sapiens	202-205
19270736-8	2009	We observed that 1% O(2) lead to an increase in the proportion of myelin basic protein (MBP)-positive OLs after 1 week in culture, and a decrease in the proportion of platelet-derived growth factor receptor alpha (PDGFRalpha)-positive cells suggesting premature OL maturation.	o(2)	20-24	myelin basic protein	Homo sapiens	88-91
18594965-0	2009	Lysophosphatidic acid can support the formation of membranous structures and an increase in MBP mRNA levels in differentiating oligodendrocytes.	lysophosphatidic acid	0-21	myelin basic protein	Homo sapiens	92-95
18594965-6	2009	In addition, LPA increased the number of cells positive for myelin basic protein (MBP).	lysophosphatidic acid	13-16	myelin basic protein	Homo sapiens	60-80
18594965-6	2009	In addition, LPA increased the number of cells positive for myelin basic protein (MBP).	lysophosphatidic acid	13-16	myelin basic protein	Homo sapiens	82-85
19270736-8	2009	We observed that 1% O(2) lead to an increase in the proportion of myelin basic protein (MBP)-positive OLs after 1 week in culture, and a decrease in the proportion of platelet-derived growth factor receptor alpha (PDGFRalpha)-positive cells suggesting premature OL maturation.	o(2)	20-24	myelin basic protein	Homo sapiens	66-86
18842736-3	2008	In this study, using the biotin label transfer technique, we found that the biotin label was transferred from Bio-rVP26 to the viral capsid protein VP51 or from Bio-MBP-VP51 to VP26.	Biotin	25-31	myelin basic protein	Homo sapiens	165-168
18842736-3	2008	In this study, using the biotin label transfer technique, we found that the biotin label was transferred from Bio-rVP26 to the viral capsid protein VP51 or from Bio-MBP-VP51 to VP26.	Biotin	76-82	myelin basic protein	Homo sapiens	165-168
17950243-5	2008	In this model of the MBP-MalFGK(2) interaction, stabilization of a high-energy conformation of MalFGK(2) allows ATP to drive conformational changes in the system - in particular the opening of bound MBP - that leads to formation of a transition state for ATP hydrolysis.	Adenosine Triphosphate	255-258	myelin basic protein	Homo sapiens	21-24
18442134-4	2008	Single cysteine residues were introduced into selected positions of ATP synthase epsilon subunit, a component of the rotor subcomplex of the enzyme, and the unrelated maltose binding protein (MBP), then the two purified recombinant proteins were crosslinked by means of a dimaleimido-PEG cross-linking agent.	Cysteine	7-15	myelin basic protein	Homo sapiens	192-195
18442134-6	2008	ATP synthase reconstituted using epsilon-PEG-MBP had reduced ATP hydrolytic activity that was uncoupled from the pumping of H(+), indicating the physical blockage of rotation of the gammaepsilonc(10) rotor by the conjugated MBP, whereas enzyme reconstituted with epsilon-PEG was normal.	epsilon-peg	33-44	myelin basic protein	Homo sapiens	45-48
18442134-6	2008	ATP synthase reconstituted using epsilon-PEG-MBP had reduced ATP hydrolytic activity that was uncoupled from the pumping of H(+), indicating the physical blockage of rotation of the gammaepsilonc(10) rotor by the conjugated MBP, whereas enzyme reconstituted with epsilon-PEG was normal.	epsilon-peg	33-44	myelin basic protein	Homo sapiens	224-227
18442134-6	2008	ATP synthase reconstituted using epsilon-PEG-MBP had reduced ATP hydrolytic activity that was uncoupled from the pumping of H(+), indicating the physical blockage of rotation of the gammaepsilonc(10) rotor by the conjugated MBP, whereas enzyme reconstituted with epsilon-PEG was normal.	Adenosine Triphosphate	0-3	myelin basic protein	Homo sapiens	45-48
18442134-6	2008	ATP synthase reconstituted using epsilon-PEG-MBP had reduced ATP hydrolytic activity that was uncoupled from the pumping of H(+), indicating the physical blockage of rotation of the gammaepsilonc(10) rotor by the conjugated MBP, whereas enzyme reconstituted with epsilon-PEG was normal.	Adenosine Triphosphate	0-3	myelin basic protein	Homo sapiens	224-227
18442134-6	2008	ATP synthase reconstituted using epsilon-PEG-MBP had reduced ATP hydrolytic activity that was uncoupled from the pumping of H(+), indicating the physical blockage of rotation of the gammaepsilonc(10) rotor by the conjugated MBP, whereas enzyme reconstituted with epsilon-PEG was normal.	epsilon-peg	263-274	myelin basic protein	Homo sapiens	45-48
18767817-2	2008	Here, we have investigated whether 18.5 kDa MBP can sequester phosphatidylinositol-(4,5)-bis-phosphate (PI(4,5)P 2) in membranes, like MARCKS and other "PIPmodulins" do.	Phosphatidylinositol 4,5-Diphosphate	62-102	myelin basic protein	Homo sapiens	44-47
18767817-2	2008	Here, we have investigated whether 18.5 kDa MBP can sequester phosphatidylinositol-(4,5)-bis-phosphate (PI(4,5)P 2) in membranes, like MARCKS and other "PIPmodulins" do.	pi(4,5)p	104-112	myelin basic protein	Homo sapiens	44-47
18767817-3	2008	Using fluorescence-quenching and electron paramagnetic resonance (EPR) spectroscopy, and model membranes containing BODIPY-FL- or proxyl-labeled PI(4,5)P 2, respectively, we have demonstrated that MBP laterally sequesters PI(4,5)P 2.	bodipy-fl	116-125	myelin basic protein	Homo sapiens	197-200
18767817-4	2008	The MBP-PI(4,5)P 2 interactions are electrostatic, partially cholesterol-dependent, and sensitive to phosphorylation, deimination, and Ca (2+)-CaM binding.	Cholesterol	61-72	myelin basic protein	Homo sapiens	4-7
18767817-4	2008	The MBP-PI(4,5)P 2 interactions are electrostatic, partially cholesterol-dependent, and sensitive to phosphorylation, deimination, and Ca (2+)-CaM binding.	cafestol palmitate	143-146	myelin basic protein	Homo sapiens	4-7
18957898-4	2008	The Aze hypothesis posits that myelin basic protein and possibly other closely related molecules are misassembled in sites of lesion formation because of the substitution of Aze for one or more prolines within consensual epitopes.	Azetidinecarboxylic Acid	4-7	myelin basic protein	Homo sapiens	31-51
18957898-4	2008	The Aze hypothesis posits that myelin basic protein and possibly other closely related molecules are misassembled in sites of lesion formation because of the substitution of Aze for one or more prolines within consensual epitopes.	Azetidinecarboxylic Acid	174-177	myelin basic protein	Homo sapiens	31-51
18957898-4	2008	The Aze hypothesis posits that myelin basic protein and possibly other closely related molecules are misassembled in sites of lesion formation because of the substitution of Aze for one or more prolines within consensual epitopes.	Proline	194-202	myelin basic protein	Homo sapiens	31-51
18832703-3	2008	The sequence of residues 111-129 of MBP (MBP(111-129)) differs in humans (MBP122:Arg) and mice (MBP122:Lys) at aa 122.	Arginine	81-84	myelin basic protein	Homo sapiens	36-39
18832703-3	2008	The sequence of residues 111-129 of MBP (MBP(111-129)) differs in humans (MBP122:Arg) and mice (MBP122:Lys) at aa 122.	Arginine	81-84	myelin basic protein	Homo sapiens	41-44
18832703-3	2008	The sequence of residues 111-129 of MBP (MBP(111-129)) differs in humans (MBP122:Arg) and mice (MBP122:Lys) at aa 122.	Lysine	103-106	myelin basic protein	Homo sapiens	36-39
18832703-3	2008	The sequence of residues 111-129 of MBP (MBP(111-129)) differs in humans (MBP122:Arg) and mice (MBP122:Lys) at aa 122.	Lysine	103-106	myelin basic protein	Homo sapiens	41-44
18832703-4	2008	We previously found that approximately 50% of human MBP(111-129) (MBP122:Arg)-specific T cell clones, including MS2-3C8 can proliferate in response to mouse MBP(111-129) (MBP122:Lys).	Arginine	73-76	myelin basic protein	Homo sapiens	52-55
18832703-4	2008	We previously found that approximately 50% of human MBP(111-129) (MBP122:Arg)-specific T cell clones, including MS2-3C8 can proliferate in response to mouse MBP(111-129) (MBP122:Lys).	Arginine	73-76	myelin basic protein	Homo sapiens	66-69
18926351-0	2008	Myelin basic protein in cerebrospinal fluid: a predictive marker of delayed encephalopathy from carbon monoxide poisoning.	Carbon Monoxide	96-111	myelin basic protein	Homo sapiens	0-20
18926351-1	2008	This study was designed to investigate whether myelin basic protein (MBP) in cerebrospinal fluid (CSF) can be a predictive marker of delayed encephalopathy from carbon monoxide (CO) poisoning.	Carbon Monoxide	161-176	myelin basic protein	Homo sapiens	47-67
18926351-1	2008	This study was designed to investigate whether myelin basic protein (MBP) in cerebrospinal fluid (CSF) can be a predictive marker of delayed encephalopathy from carbon monoxide (CO) poisoning.	Carbon Monoxide	161-176	myelin basic protein	Homo sapiens	69-72
18926351-1	2008	This study was designed to investigate whether myelin basic protein (MBP) in cerebrospinal fluid (CSF) can be a predictive marker of delayed encephalopathy from carbon monoxide (CO) poisoning.	Carbon Monoxide	178-180	myelin basic protein	Homo sapiens	47-67
18926351-1	2008	This study was designed to investigate whether myelin basic protein (MBP) in cerebrospinal fluid (CSF) can be a predictive marker of delayed encephalopathy from carbon monoxide (CO) poisoning.	Carbon Monoxide	178-180	myelin basic protein	Homo sapiens	69-72
17950243-2	2008	The interaction between MBP and MalFGK(2) has a critical role in maltose transport, but a coherent description of the interaction is complicated because both MBP and MalFGK(2) can adopt multiple conformations.	Maltose	65-72	myelin basic protein	Homo sapiens	24-27
17950243-2	2008	The interaction between MBP and MalFGK(2) has a critical role in maltose transport, but a coherent description of the interaction is complicated because both MBP and MalFGK(2) can adopt multiple conformations.	Maltose	65-72	myelin basic protein	Homo sapiens	158-161
17950243-4	2008	The most important feature of this model is that ligand-bound MBP initiates the process of ATP-dependent maltose transport by stabilizing a high-energy conformation of MalFGK(2).	Adenosine Triphosphate	91-94	myelin basic protein	Homo sapiens	62-65
17950243-4	2008	The most important feature of this model is that ligand-bound MBP initiates the process of ATP-dependent maltose transport by stabilizing a high-energy conformation of MalFGK(2).	Maltose	105-112	myelin basic protein	Homo sapiens	62-65
17950243-5	2008	In this model of the MBP-MalFGK(2) interaction, stabilization of a high-energy conformation of MalFGK(2) allows ATP to drive conformational changes in the system - in particular the opening of bound MBP - that leads to formation of a transition state for ATP hydrolysis.	Adenosine Triphosphate	112-115	myelin basic protein	Homo sapiens	21-24
17950243-5	2008	In this model of the MBP-MalFGK(2) interaction, stabilization of a high-energy conformation of MalFGK(2) allows ATP to drive conformational changes in the system - in particular the opening of bound MBP - that leads to formation of a transition state for ATP hydrolysis.	Adenosine Triphosphate	112-115	myelin basic protein	Homo sapiens	199-202
17950243-5	2008	In this model of the MBP-MalFGK(2) interaction, stabilization of a high-energy conformation of MalFGK(2) allows ATP to drive conformational changes in the system - in particular the opening of bound MBP - that leads to formation of a transition state for ATP hydrolysis.	Adenosine Triphosphate	255-258	myelin basic protein	Homo sapiens	199-202
17950243-7	2008	In ABC export systems, which do not use a binding protein, the substrate itself is expected to play a role similar to ligand-bound MBP in the maltose transport system.	Maltose	142-149	myelin basic protein	Homo sapiens	131-134
18570438-9	2008	Both spectroscopic and X-ray structural studies are consistent with inhibition resulting from the binding of MBP to the thiamin diphosphate in the active centers.	Thiamine Pyrophosphate	120-139	myelin basic protein	Homo sapiens	109-112