PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 32303304-4 2020 In this work, the effect of the administration of PL to horses with OA was analyzed both clinically and molecularly by determining the levels of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5), glycosaminoglycans (GAGs), and tissue inhibitor of metalloproteinase 1 (TIMP-1) in synovial fluid. pl 50-52 matrix metallopeptidase 9 Equus caballus 181-207 33834598-3 2021 OBJECTIVE: To determine if bovine and equine AMH reduce in vitro MMP-2 and MMP-9 activities associated with the presence of TIMPs. Tranexamic Acid 45-48 matrix metallopeptidase 9 Equus caballus 75-80 32442743-8 2020 Prostaglandin E2 increased MMP-2 and MMP-9, and decreased MMP-13 secretion by endometrial fibroblasts (P < 0.05). Dinoprostone 0-16 matrix metallopeptidase 9 Equus caballus 37-42 32429399-3 2020 The aim was to evaluate the effects of ELA and sivelestat (selective elastase inhibitor) on MMP-2 and MMP-9 expression and gelatinolytic activity, as well as the potential inhibitory effect of sivelestat on ELA-induced COL1 in equine endometrium. sivelestat 47-57 matrix metallopeptidase 9 Equus caballus 102-107 32303304-4 2020 In this work, the effect of the administration of PL to horses with OA was analyzed both clinically and molecularly by determining the levels of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5), glycosaminoglycans (GAGs), and tissue inhibitor of metalloproteinase 1 (TIMP-1) in synovial fluid. pl 50-52 matrix metallopeptidase 9 Equus caballus 209-214 32303304-7 2020 The levels of MMP-9 decreased significantly (P < .05) on day 10 after treatment with PL. pl 85-87 matrix metallopeptidase 9 Equus caballus 14-19 32303304-12 2020 In conclusion, the beneficial effects of PL in OA could be attributed to the decreased activity of MMP-2, MMP-9, and ADAMTS-5 and the increased concentration of GAGs and TIMP-1 after the administration of platelet-rich plasma. pl 41-43 matrix metallopeptidase 9 Equus caballus 106-111 16822550-5 2006 Control laminae were devoid of both MMP-9 and neutrophils, whereas neutrophils and SDS-renaturable MMP-9 activity were detected in laminae from BWE-treated horses and were strongly correlated at the acute stage of the disease at which time laminar MMP-9 gene expression was significantly (15-fold) elevated. Sodium Dodecyl Sulfate 83-86 matrix metallopeptidase 9 Equus caballus 99-104 25126665-6 2014 Real-time PCR was used to determine the effects of SAHA on MMP2 and MMP9 expression. Vorinostat 51-55 matrix metallopeptidase 9 Equus caballus 68-72 25126665-9 2014 SAHA treatment also resulted in 4.5- to 5.5-fold (P < 0.01) decrease in MMP9 expression. Vorinostat 0-4 matrix metallopeptidase 9 Equus caballus 75-79 21459025-1 2011 The aim of this study was to determine if hypoxia and the hypoxia mimetic cobalt chloride regulate the activity of matrix metalloproteinase (MMP)-2 and -9 in cultures of equine hoof keratinocytes. cobaltous chloride 74-89 matrix metallopeptidase 9 Equus caballus 115-154 31412868-15 2019 MMP-9 decreased at 3-months at -20 C, and at all times at -80 C and in liquid nitrogen compared to snap frozen (p < 0.0001). Nitrogen 80-88 matrix metallopeptidase 9 Equus caballus 0-5 23438126-10 2013 Pentoxifylline and oxytetracycline appeared to be the most effective MMP-2 and MMP-9 inhibitors, whereas doxycycline and flunixin meglumine were more effective at inhibiting MMP-2 activity than MMP-9 activity. Pentoxifylline 0-14 matrix metallopeptidase 9 Equus caballus 79-84 23438126-10 2013 Pentoxifylline and oxytetracycline appeared to be the most effective MMP-2 and MMP-9 inhibitors, whereas doxycycline and flunixin meglumine were more effective at inhibiting MMP-2 activity than MMP-9 activity. Oxytetracycline 19-34 matrix metallopeptidase 9 Equus caballus 79-84 16822550-5 2006 Control laminae were devoid of both MMP-9 and neutrophils, whereas neutrophils and SDS-renaturable MMP-9 activity were detected in laminae from BWE-treated horses and were strongly correlated at the acute stage of the disease at which time laminar MMP-9 gene expression was significantly (15-fold) elevated. Sodium Dodecyl Sulfate 83-86 matrix metallopeptidase 9 Equus caballus 99-104 12405691-15 2002 The combination of GLN/CS decreased MMP-9 gelatinolytic activity but had no effect on MMP-2 activity. Glutamine 19-22 matrix metallopeptidase 9 Equus caballus 36-41 12405691-15 2002 The combination of GLN/CS decreased MMP-9 gelatinolytic activity but had no effect on MMP-2 activity. Chondroitin Sulfates 23-25 matrix metallopeptidase 9 Equus caballus 36-41 16163942-9 2005 The fact that HDS-1 and HDS-2 had different glucan concentrations supports a role for moulds in the activation of MMP-9. Glucans 44-50 matrix metallopeptidase 9 Equus caballus 114-119