PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 10084689-5 1999 Bromodeoxyuridine labeling studies demonstrated that P10 as well as P6 cultures contained neurons only from the EGL. Bromodeoxyuridine 0-17 S100 calcium binding protein A10 Homo sapiens 53-56 10460796-5 1999 Moreover, a mixture of GST isoenzymes purified from rat liver, and three recombinant human GST isoforms, A1-1, M1-1, and P1-1, were active toward PNU-109112 sulfonamide cleavage; the three isoforms exhibited differential rates of PNU-109112 cleavage, demonstrating isoenzyme selectivity. pnu-109112 sulfonamide 146-168 S100 calcium binding protein A10 Homo sapiens 121-125 10460796-5 1999 Moreover, a mixture of GST isoenzymes purified from rat liver, and three recombinant human GST isoforms, A1-1, M1-1, and P1-1, were active toward PNU-109112 sulfonamide cleavage; the three isoforms exhibited differential rates of PNU-109112 cleavage, demonstrating isoenzyme selectivity. N-neopentyl-N-nitrosourea 146-149 S100 calcium binding protein A10 Homo sapiens 121-125 10407081-1 1999 The interaction of p-10,12-pentacosadiyne-1-n-phenylamide alpha-D-mannopyranoside (MPDA) with protein concanavalin A (Con A) was studied at the air/water interface. 3-(2'-pyridyldithio)benzyldiazoacetate 83-87 S100 calcium binding protein A10 Homo sapiens 19-23 10407081-1 1999 The interaction of p-10,12-pentacosadiyne-1-n-phenylamide alpha-D-mannopyranoside (MPDA) with protein concanavalin A (Con A) was studied at the air/water interface. Water 148-153 S100 calcium binding protein A10 Homo sapiens 19-23 10358078-8 1999 Cloned HeLa cells expressing p11 antisense mRNA exhibited less cellular p11 protein compared with control cells and greater [3H]AA release compared with cells transfected with a control vector. Tritium 125-127 S100 calcium binding protein A10 Homo sapiens 29-32 10358078-9 1999 Cloned HeLa cells stably transfected with a p11 expression vector exhibited increased p11 cellular protein and diminished [3H]AA release under basal conditions and in response to A23187. Tritium 123-125 S100 calcium binding protein A10 Homo sapiens 44-47 10358078-9 1999 Cloned HeLa cells stably transfected with a p11 expression vector exhibited increased p11 cellular protein and diminished [3H]AA release under basal conditions and in response to A23187. Calcimycin 179-185 S100 calcium binding protein A10 Homo sapiens 44-47 10358078-10 1999 Therefore, dexamethasone alteration of epithelial cell AA release may be due in part to induction of p11 protein expression. Dexamethasone 11-24 S100 calcium binding protein A10 Homo sapiens 101-104 9882456-6 1999 In contrast to the Alpha and Mu classes being selective for strongly electrophilic compounds, the neoplastic P1-1 species was indicated to be selective for weakly electrophilic and water-soluble carcinogens such as acrolein and hydroxyalkenals. Water 181-186 S100 calcium binding protein A10 Homo sapiens 109-113 9882456-6 1999 In contrast to the Alpha and Mu classes being selective for strongly electrophilic compounds, the neoplastic P1-1 species was indicated to be selective for weakly electrophilic and water-soluble carcinogens such as acrolein and hydroxyalkenals. Acrolein 215-223 S100 calcium binding protein A10 Homo sapiens 109-113 9882456-6 1999 In contrast to the Alpha and Mu classes being selective for strongly electrophilic compounds, the neoplastic P1-1 species was indicated to be selective for weakly electrophilic and water-soluble carcinogens such as acrolein and hydroxyalkenals. hydroxyalkenals 228-243 S100 calcium binding protein A10 Homo sapiens 109-113 10358078-0 1999 Dexamethasone alters arachidonate release from human epithelial cells by induction of p11 protein synthesis and inhibition of phospholipase A2 activity. Dexamethasone 0-13 S100 calcium binding protein A10 Homo sapiens 86-89 10358078-0 1999 Dexamethasone alters arachidonate release from human epithelial cells by induction of p11 protein synthesis and inhibition of phospholipase A2 activity. Arachidonic Acid 21-33 S100 calcium binding protein A10 Homo sapiens 86-89 10358078-2 1999 Dexamethasone treatment of HeLa cells and BEAS-2B cells increased cellular p11 protein and mRNA levels in a time- and dose-dependent manner. Dexamethasone 0-13 S100 calcium binding protein A10 Homo sapiens 75-78 10358078-5 1999 In cells treated with dexamethasone, more p11 was detected in the anti-cPLA2 immunoprecipitate compared with control cells. Dexamethasone 22-35 S100 calcium binding protein A10 Homo sapiens 42-45 9843686-4 1998 In this study, we show that mammalian p10/NTF2 dramatically inhibits the dissociation of [3H]GDP from Ran and the binding of [35S]GTPgammaS to Ran following the dissociation of non-radioactive GDP by RCC1, the only known mammalian guanine nucleotide exchange factor for Ran (Ran-GEF) [7]. Guanine Nucleotides 231-249 S100 calcium binding protein A10 Homo sapiens 38-41 9886297-1 1999 The aggregation and membrane fusion properties of annexin II are modulated by the association with a regulatory light chain called p11.p11 is a member of the S100 EF-hand protein family, which is unique in having lost its calcium-binding properties. Calcium 222-229 S100 calcium binding protein A10 Homo sapiens 131-134 9886297-1 1999 The aggregation and membrane fusion properties of annexin II are modulated by the association with a regulatory light chain called p11.p11 is a member of the S100 EF-hand protein family, which is unique in having lost its calcium-binding properties. Calcium 222-229 S100 calcium binding protein A10 Homo sapiens 135-138 9886297-5 1999 Finally, p11 forms a disulfide-linked tetramer in both types of crystals thus suggesting a model for an oxidized form of other S100 proteins that have been found in the extracellular milieu. Disulfides 21-30 S100 calcium binding protein A10 Homo sapiens 9-12 9843686-6 1998 Furthermore, the activities of wild-type p10/NTF2 and the mutant forms M84T and D92G in an assay of nuclear protein import in a digitonin-permeabilized cell-free system correlated with their level of inhibition of the dissociation of nucleotide from Ran-GDP. Digitonin 128-137 S100 calcium binding protein A10 Homo sapiens 41-44 9843686-0 1998 Nuclear transport factor p10/NTF2 functions as a Ran-GDP dissociation inhibitor (Ran-GDI). Guanosine Diphosphate 53-56 S100 calcium binding protein A10 Homo sapiens 25-28 9843686-3 1998 The precise role(s) of p10/NTF2 in the Ran GTP/GDP cycle are thus far unclear, however. Guanosine Triphosphate 43-46 S100 calcium binding protein A10 Homo sapiens 23-26 9843686-6 1998 Furthermore, the activities of wild-type p10/NTF2 and the mutant forms M84T and D92G in an assay of nuclear protein import in a digitonin-permeabilized cell-free system correlated with their level of inhibition of the dissociation of nucleotide from Ran-GDP. Guanosine Diphosphate 254-257 S100 calcium binding protein A10 Homo sapiens 41-44 9843686-3 1998 The precise role(s) of p10/NTF2 in the Ran GTP/GDP cycle are thus far unclear, however. Guanosine Diphosphate 47-50 S100 calcium binding protein A10 Homo sapiens 23-26 9843686-4 1998 In this study, we show that mammalian p10/NTF2 dramatically inhibits the dissociation of [3H]GDP from Ran and the binding of [35S]GTPgammaS to Ran following the dissociation of non-radioactive GDP by RCC1, the only known mammalian guanine nucleotide exchange factor for Ran (Ran-GEF) [7]. Tritium 90-92 S100 calcium binding protein A10 Homo sapiens 38-41 9843686-7 1998 These results suggest that p10/NTF2 acts as a GDP dissociation inhibitor for Ran (Ran-GDI), thereby coordinating the Ran-dependent reactions that underlie nuclear protein import. Guanosine Diphosphate 46-49 S100 calcium binding protein A10 Homo sapiens 27-30 9843686-4 1998 In this study, we show that mammalian p10/NTF2 dramatically inhibits the dissociation of [3H]GDP from Ran and the binding of [35S]GTPgammaS to Ran following the dissociation of non-radioactive GDP by RCC1, the only known mammalian guanine nucleotide exchange factor for Ran (Ran-GEF) [7]. Guanosine Diphosphate 93-96 S100 calcium binding protein A10 Homo sapiens 38-41 9843686-4 1998 In this study, we show that mammalian p10/NTF2 dramatically inhibits the dissociation of [3H]GDP from Ran and the binding of [35S]GTPgammaS to Ran following the dissociation of non-radioactive GDP by RCC1, the only known mammalian guanine nucleotide exchange factor for Ran (Ran-GEF) [7]. Sulfur-35 126-129 S100 calcium binding protein A10 Homo sapiens 38-41 9932109-5 1998 RESULTS: We show here that the cAMP-dependent protein kinase (PKA) effectors, dibutyryl-cAMP (dBut-cAMP) and forskolin, but not the inactive analog dideoxyforskolin, enhance the secretion of APP alpha and the intracellular production of its C-terminal counterpart (p10) in stably transfected HEK293 cells. Cyclic AMP 31-35 S100 calcium binding protein A10 Homo sapiens 265-268 9843686-4 1998 In this study, we show that mammalian p10/NTF2 dramatically inhibits the dissociation of [3H]GDP from Ran and the binding of [35S]GTPgammaS to Ran following the dissociation of non-radioactive GDP by RCC1, the only known mammalian guanine nucleotide exchange factor for Ran (Ran-GEF) [7]. Guanosine Diphosphate 193-196 S100 calcium binding protein A10 Homo sapiens 38-41 9836589-3 1998 In this report, we have compared the ability of the isolated p36 and p11 subunits to stimulate t-PA-dependent [Glu]plasminogen activation. Glutamic Acid 111-114 S100 calcium binding protein A10 Homo sapiens 69-72 9836589-4 1998 The fluid-phase recombinant p11 subunit stimulated the rate of t-PA-dependent activation of [Glu]plasminogen about 46-fold compared to an approximate stimulation of 2-fold by the recombinant p36 subunit and 77-fold by recombinant AIIt. Glutamic Acid 93-96 S100 calcium binding protein A10 Homo sapiens 28-31 9836589-5 1998 The stimulation of t-PA-dependent activation of [Glu]plasminogen by the p11 subunit was Ca2+-independent and inhibited by epsilon-aminocaproic acid. Aminocaproic Acid 122-147 S100 calcium binding protein A10 Homo sapiens 72-75 9836589-6 1998 [Glu]Plasminogen bound to a p11 subunit affinity column and could be eluted with epsilon-aminocaproic acid. Aminocaproic Acid 81-106 S100 calcium binding protein A10 Homo sapiens 28-31 9836589-9 1998 In addition, a deletion mutant of the p11 subunit, missing the last two C-terminal lysine residues, retained only about 15% of the activity of the wild-type p11 subunit. Lysine 83-89 S100 calcium binding protein A10 Homo sapiens 38-41 9836589-11 1998 These results, therefore, suggest that the C-terminal lysine residues of the p11 subunit bind plasminogen and participate in the stimulation of t-PA-dependent activation of plasminogen by AIIt. Lysine 54-60 S100 calcium binding protein A10 Homo sapiens 77-80 9932109-5 1998 RESULTS: We show here that the cAMP-dependent protein kinase (PKA) effectors, dibutyryl-cAMP (dBut-cAMP) and forskolin, but not the inactive analog dideoxyforskolin, enhance the secretion of APP alpha and the intracellular production of its C-terminal counterpart (p10) in stably transfected HEK293 cells. Bucladesine 78-92 S100 calcium binding protein A10 Homo sapiens 265-268 9932109-5 1998 RESULTS: We show here that the cAMP-dependent protein kinase (PKA) effectors, dibutyryl-cAMP (dBut-cAMP) and forskolin, but not the inactive analog dideoxyforskolin, enhance the secretion of APP alpha and the intracellular production of its C-terminal counterpart (p10) in stably transfected HEK293 cells. Bucladesine 94-103 S100 calcium binding protein A10 Homo sapiens 265-268 9932109-5 1998 RESULTS: We show here that the cAMP-dependent protein kinase (PKA) effectors, dibutyryl-cAMP (dBut-cAMP) and forskolin, but not the inactive analog dideoxyforskolin, enhance the secretion of APP alpha and the intracellular production of its C-terminal counterpart (p10) in stably transfected HEK293 cells. Colforsin 109-118 S100 calcium binding protein A10 Homo sapiens 265-268 9398678-5 1997 T42A-Ran.GDP also retains the ability to bind p10/NTF2, a component of the nuclear import pathway. Guanosine Diphosphate 9-12 S100 calcium binding protein A10 Homo sapiens 46-49 10028341-6 1998 As cut-off point for referral SDS < -1.3 (< P10) was chosen in order to identify risk groups that need further evaluation. sds 30-33 S100 calcium binding protein A10 Homo sapiens 50-53 9403173-0 1997 Glutathione conjugation of bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferases M1-1 and P1-1. Glutathione 0-11 S100 calcium binding protein A10 Homo sapiens 127-140 9398518-0 1997 The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution. Glutathione 24-35 S100 calcium binding protein A10 Homo sapiens 48-52 9403173-0 1997 Glutathione conjugation of bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferases M1-1 and P1-1. diol epoxides 49-62 S100 calcium binding protein A10 Homo sapiens 127-140 9403173-0 1997 Glutathione conjugation of bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferases M1-1 and P1-1. Polycyclic Aromatic Hydrocarbons 66-98 S100 calcium binding protein A10 Homo sapiens 127-140 9403173-3 1997 As previously shown with GSTA1-1 (an alpha-class enzyme) both M1-1 and P1-1 demonstrate considerable activity toward a number of the diol epoxides studied, although a great variation in catalytic efficiency and enantioselectivity was observed. diol epoxides 133-146 S100 calcium binding protein A10 Homo sapiens 62-75 9351803-6 1997 RESULTS: We have solved the structures of the pi class GST hP1-1 in complex with its substrate, glutathione, a transition-state complex, the Meisenheimer complex, and an inhibitor, S-(rho-bromobenzyl)-glutathione, and refined them to resolutions of 1.8 A, 2.0 A and 1.9 A, respectively. Glutathione 96-107 S100 calcium binding protein A10 Homo sapiens 59-64 9369453-8 1997 P11, a nerve growth factor-induced neurite extension factor and member of the calcium-binding S-100 protein family, interacted strongly with the mutant BAD but less effectively with the wild type protein. Calcium 78-85 S100 calcium binding protein A10 Homo sapiens 0-3 9351803-6 1997 RESULTS: We have solved the structures of the pi class GST hP1-1 in complex with its substrate, glutathione, a transition-state complex, the Meisenheimer complex, and an inhibitor, S-(rho-bromobenzyl)-glutathione, and refined them to resolutions of 1.8 A, 2.0 A and 1.9 A, respectively. s-(rho-bromobenzyl)-glutathione 181-212 S100 calcium binding protein A10 Homo sapiens 59-64 9230210-9 1997 Furthermore, overexpression of p10 together with p15 in COS-7 cells did not interfere with the complex formation of p15 with CDK4 or CDK6. carbonyl sulfide 56-59 S100 calcium binding protein A10 Homo sapiens 31-34 9247290-7 1997 Metabolically radiolabeled O-linked oligosaccharides with sialyl-Lewis(a) antigenic reactivity eluted from Bio-Gel P-10 in the region of sialylated and sulfated oligosaccharides. o-linked oligosaccharides 27-52 S100 calcium binding protein A10 Homo sapiens 115-119 9247290-7 1997 Metabolically radiolabeled O-linked oligosaccharides with sialyl-Lewis(a) antigenic reactivity eluted from Bio-Gel P-10 in the region of sialylated and sulfated oligosaccharides. Oligosaccharides 36-52 S100 calcium binding protein A10 Homo sapiens 115-119 9247290-9 1997 Even after desialylation and desulfation, oligosaccharides eluted from Bio-Gel P-10 with apparent molecular sizes greater than glucose oligomers of 12 units. Oligosaccharides 42-58 S100 calcium binding protein A10 Homo sapiens 79-83 9202034-1 1997 Using a two hybrid system screen of a human cDNA library, we have found that p11, a unique member of the S100 family of calcium-binding proteins, interacts with the carboxyl region of the 85-kDa cytosolic phospholipase A2 (cPLA2). Calcium 120-127 S100 calcium binding protein A10 Homo sapiens 77-80 9202034-5 1997 Selective inhibition of p11 expression in the BEAS 2B cells by antisense RNA results in an increased PLA2 activity as well as an increased release of prelabeled arachidonic acid. Arachidonic Acid 161-177 S100 calcium binding protein A10 Homo sapiens 24-27 9139722-10 1997 The active forms of both PAI-1-P10(Ser --> Pro) and PAI-1-P18(Asn --> Pro) are also labile but, in contrast to the active form of wtPAI-1, convert into substrate forms. Serine 35-38 S100 calcium binding protein A10 Homo sapiens 31-34 9139722-7 1997 PAI-1-P6 (Val --> Pro at P6) revealed a target specificity for t-PA (39 +/- 7% versus 3 +/- 2% of the theoretical maximal value toward t-PA and u-PA, respectively), PAI-1-P10 (Ser --> Pro at P10) was 4-fold more active toward u-PA than toward t-PA, and PAI-1-P18 (Asn --> Pro at P18) exhibited inhibitory properties exclusively toward u-PA (41 +/- 10%). Valine 10-13 S100 calcium binding protein A10 Homo sapiens 174-177 9139722-7 1997 PAI-1-P6 (Val --> Pro at P6) revealed a target specificity for t-PA (39 +/- 7% versus 3 +/- 2% of the theoretical maximal value toward t-PA and u-PA, respectively), PAI-1-P10 (Ser --> Pro at P10) was 4-fold more active toward u-PA than toward t-PA, and PAI-1-P18 (Asn --> Pro at P18) exhibited inhibitory properties exclusively toward u-PA (41 +/- 10%). Proline 21-24 S100 calcium binding protein A10 Homo sapiens 174-177 9139722-10 1997 The active forms of both PAI-1-P10(Ser --> Pro) and PAI-1-P18(Asn --> Pro) are also labile but, in contrast to the active form of wtPAI-1, convert into substrate forms. Proline 46-49 S100 calcium binding protein A10 Homo sapiens 31-34 9139722-7 1997 PAI-1-P6 (Val --> Pro at P6) revealed a target specificity for t-PA (39 +/- 7% versus 3 +/- 2% of the theoretical maximal value toward t-PA and u-PA, respectively), PAI-1-P10 (Ser --> Pro at P10) was 4-fold more active toward u-PA than toward t-PA, and PAI-1-P18 (Asn --> Pro at P18) exhibited inhibitory properties exclusively toward u-PA (41 +/- 10%). Proline 21-24 S100 calcium binding protein A10 Homo sapiens 197-200 9139722-7 1997 PAI-1-P6 (Val --> Pro at P6) revealed a target specificity for t-PA (39 +/- 7% versus 3 +/- 2% of the theoretical maximal value toward t-PA and u-PA, respectively), PAI-1-P10 (Ser --> Pro at P10) was 4-fold more active toward u-PA than toward t-PA, and PAI-1-P18 (Asn --> Pro at P18) exhibited inhibitory properties exclusively toward u-PA (41 +/- 10%). Valine 10-13 S100 calcium binding protein A10 Homo sapiens 197-200 9183003-0 1997 Inhibition of human placenta glutathione transferase P1-1 by the antibiotic calvatic acid and its diazocyanide analogue--evidence for multiple catalytic intermediates. calvatic acid 76-89 S100 calcium binding protein A10 Homo sapiens 53-57 9183003-0 1997 Inhibition of human placenta glutathione transferase P1-1 by the antibiotic calvatic acid and its diazocyanide analogue--evidence for multiple catalytic intermediates. Diazocyanide 98-110 S100 calcium binding protein A10 Homo sapiens 53-57 9105036-7 1997 In leupeptin, I-A(b) dimers formed stable complexes with a 10-kD NH2-terminal Ii chain fragment (Ii-p10), normally a transient intermediate in Ii chain processing. leupeptin 3-12 S100 calcium binding protein A10 Homo sapiens 100-103 9105036-8 1997 Upon removal of leupeptin, Ii-p10 was degraded and released, I-A(b) dimers bound antigenic peptides, and the peptide-loaded dimers were transported slowly from lysosomes to the plasma membrane. leupeptin 16-25 S100 calcium binding protein A10 Homo sapiens 30-33 9084911-0 1997 Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1. prostaglandin A2 31-47 S100 calcium binding protein A10 Homo sapiens 161-165 9084911-0 1997 Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1. 9-deoxy-delta-9-prostaglandin D2 52-68 S100 calcium binding protein A10 Homo sapiens 161-165 9084911-0 1997 Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1. Glutathione 74-85 S100 calcium binding protein A10 Homo sapiens 161-165 8955342-1 1996 p10/NTF2 is a cytosolic factor which is required for the translocation step in nuclear protein import in an in vitro assay with digitonin-permeabilized cells. Digitonin 128-137 S100 calcium binding protein A10 Homo sapiens 0-3 8898866-3 1996 The annexin II-p11 interaction is mediated through the unique N-terminal domain of annexin II and is inhibited by protein kinase C phosphorylation of a serine residue in annexin II. Serine 152-158 S100 calcium binding protein A10 Homo sapiens 15-18 8870658-7 1996 Thus the structural basis of the annexin 1-S100C complex-formation probably resembles to a large extent that of the well-characterized annexin II-p11 interaction. annexin 1 33-42 S100 calcium binding protein A10 Homo sapiens 146-149 8898866-6 1996 However, significant differences in phosphate incorporation were observed when the individual serine mutants were subjected to phosphorylation by protein kinase C. A comparison of the phosphorylation patterns obtained identified Ser-II as the protein kinase C site responsible for regulating the annexin II-p11 interaction. Serine 94-100 S100 calcium binding protein A10 Homo sapiens 307-310 8898866-6 1996 However, significant differences in phosphate incorporation were observed when the individual serine mutants were subjected to phosphorylation by protein kinase C. A comparison of the phosphorylation patterns obtained identified Ser-II as the protein kinase C site responsible for regulating the annexin II-p11 interaction. ser-ii 229-235 S100 calcium binding protein A10 Homo sapiens 307-310 8898866-7 1996 Ser-II lies within the sequence mediating p11 binding, i.e. amino-acid residues 1 to 14 of annexin II, and phosphorylation at this site most likely leads to a direct spatial interference with p11 binding. Serine 0-3 S100 calcium binding protein A10 Homo sapiens 42-45 8898866-7 1996 Ser-II lies within the sequence mediating p11 binding, i.e. amino-acid residues 1 to 14 of annexin II, and phosphorylation at this site most likely leads to a direct spatial interference with p11 binding. Serine 0-3 S100 calcium binding protein A10 Homo sapiens 192-195 8706744-7 1996 The p10 host factor complex was specifically competed out with oligonucleotides containing p29 cognate sequence motifs AATAAA and TAAGTATT, but this did not occur when these motifs were replaced with random sequences. Oligonucleotides 63-79 S100 calcium binding protein A10 Homo sapiens 4-7 8663073-2 1996 Presteady-state and steady-state kinetics of human glutathione transferase P1-1 (EC 2.5.1.18) have been studied at pH 5.0 by using 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole, a poor co-substrate for this isoenzyme. 4-Chloro-7-nitrobenzofurazan 131-170 S100 calcium binding protein A10 Homo sapiens 75-79 8678907-0 1996 Interaction of glutathione transferase P1-1 with captan and captafol. Captan 49-55 S100 calcium binding protein A10 Homo sapiens 39-43 8682860-7 1996 The light chain of annexin II, p11, was selectively expressed by adrenergic chromaffin cells, and was only present in the subplasmalemmal Triton X-100 insoluble protein fraction of both resting and stimulated cells. chromaffin 76-86 S100 calcium binding protein A10 Homo sapiens 31-34 8678907-0 1996 Interaction of glutathione transferase P1-1 with captan and captafol. captafol 60-68 S100 calcium binding protein A10 Homo sapiens 39-43 8678907-1 1996 Glutathione transferase (GST, EC 2.5.1.18) P1-1 was strongly inhibited by captan and captafol in a time- and concentration-dependent manner. Captan 74-80 S100 calcium binding protein A10 Homo sapiens 43-47 8678907-1 1996 Glutathione transferase (GST, EC 2.5.1.18) P1-1 was strongly inhibited by captan and captafol in a time- and concentration-dependent manner. captafol 85-93 S100 calcium binding protein A10 Homo sapiens 43-47 8662843-11 1996 Cleavage of p45 by exogenous p20/p10 ICE differs from that of the endogenous p45 cleavage activity in that the p20/p10 activity is more salt sensitive, and it produces a different pattern of cleavage fragments, principally 35- and 12-kDa fragments. Salts 136-140 S100 calcium binding protein A10 Homo sapiens 33-36 8662843-11 1996 Cleavage of p45 by exogenous p20/p10 ICE differs from that of the endogenous p45 cleavage activity in that the p20/p10 activity is more salt sensitive, and it produces a different pattern of cleavage fragments, principally 35- and 12-kDa fragments. Salts 136-140 S100 calcium binding protein A10 Homo sapiens 115-118 8682860-7 1996 The light chain of annexin II, p11, was selectively expressed by adrenergic chromaffin cells, and was only present in the subplasmalemmal Triton X-100 insoluble protein fraction of both resting and stimulated cells. Octoxynol 138-150 S100 calcium binding protein A10 Homo sapiens 31-34 7564160-7 1995 The analysis of two paraffin-embedded tumors suggested that changes in the size of the pericentromeric hybridization signals of chromosome 12 may be attributed to the presence of i(12)(p10). Paraffin 20-28 S100 calcium binding protein A10 Homo sapiens 185-188 8682860-8 1996 p11 can modify the Ca(2+)- and/or the phospholipid-binding properties of p36. Phospholipids 38-50 S100 calcium binding protein A10 Homo sapiens 0-3 8620581-7 1996 The human GST isoenzymes A1-1, M1a-1a and P1-1 and the rat GST isoenzymes 1-1, 2-2, 3-3, 4-4 and 7-7 were irreversibly inhibited by eugenol in the presence of tyrosinase. Eugenol 132-139 S100 calcium binding protein A10 Homo sapiens 42-46 8546709-1 1996 Annexin II (p36) and p11, which belong to two different families of calcium-binding proteins, are able to form a heterotetrameric protein complex (p36)2(p11)2 called calpactin I. Calcium 68-75 S100 calcium binding protein A10 Homo sapiens 21-24 8546709-1 1996 Annexin II (p36) and p11, which belong to two different families of calcium-binding proteins, are able to form a heterotetrameric protein complex (p36)2(p11)2 called calpactin I. Calcium 68-75 S100 calcium binding protein A10 Homo sapiens 153-156 8671651-9 1996 Instead a Pro at P3, a Phe at P7 and an Ile at P10 are utilized for MHC binding. Isoleucine 40-43 S100 calcium binding protein A10 Homo sapiens 47-50 7495819-6 1995 Following the glutamate substitution at P10, alpha1-antitrypsin remained a rapid inhibitor of elastase, but the elastase--serpin complex slowly broke down to yield active elastase and cleaved alpha1-antitrypsin. Glutamic Acid 14-23 S100 calcium binding protein A10 Homo sapiens 40-43 7487881-1 1995 The catalytic properties of four human glutathione transferases (GSTs), A1-1, M1-1, M4-4 and P1-1, were examined with 14 isothiocyanate (R-NCS) substrates. isothiocyanic acid 121-135 S100 calcium binding protein A10 Homo sapiens 93-97 7487881-1 1995 The catalytic properties of four human glutathione transferases (GSTs), A1-1, M1-1, M4-4 and P1-1, were examined with 14 isothiocyanate (R-NCS) substrates. r-ncs 137-142 S100 calcium binding protein A10 Homo sapiens 93-97 7712478-14 1995 Both GST A1-1 and P1-1 could enhance the formation of the glutathione conjugate 37-46-fold above the spontaneous levels, while GST M1a-1a and A2-2 again did not increase the rate of formation of this conjugate. Glutathione 58-69 S100 calcium binding protein A10 Homo sapiens 18-22 7541430-3 1995 Three overlapping regions could be defined on the insulin molecule coupled to the dextran matrix on the basis of its recognition by three mAbs groups: group I (mAbs 19, 10), group II (mAbs 13, 5, 25, 15) and group III (mAb P10). Dextrans 82-89 S100 calcium binding protein A10 Homo sapiens 223-226 7712478-15 1995 The results of these studies show that the aziridine moieties in thiotepa/tepa are substrates for both GST A1-1 and P1-1. aziridine 43-52 S100 calcium binding protein A10 Homo sapiens 116-120 7712478-9 1995 In incubations with 0.2 mM thiotepa, 1 mM GSH, and 40 microM GST, both GST A1-1 and P1-1 enhanced the formation of the monoglutathionyl conjugate 30-35-fold above the nonenzymatic formation, while GST A2-2 and M1a-1a did not catalyze the rate of formation of this conjugate. Thiotepa 27-35 S100 calcium binding protein A10 Homo sapiens 84-88 7712478-9 1995 In incubations with 0.2 mM thiotepa, 1 mM GSH, and 40 microM GST, both GST A1-1 and P1-1 enhanced the formation of the monoglutathionyl conjugate 30-35-fold above the nonenzymatic formation, while GST A2-2 and M1a-1a did not catalyze the rate of formation of this conjugate. Glutathione 42-45 S100 calcium binding protein A10 Homo sapiens 84-88 7712478-15 1995 The results of these studies show that the aziridine moieties in thiotepa/tepa are substrates for both GST A1-1 and P1-1. Thiotepa 65-73 S100 calcium binding protein A10 Homo sapiens 116-120 7712478-9 1995 In incubations with 0.2 mM thiotepa, 1 mM GSH, and 40 microM GST, both GST A1-1 and P1-1 enhanced the formation of the monoglutathionyl conjugate 30-35-fold above the nonenzymatic formation, while GST A2-2 and M1a-1a did not catalyze the rate of formation of this conjugate. monoglutathionyl 119-135 S100 calcium binding protein A10 Homo sapiens 84-88 7712478-15 1995 The results of these studies show that the aziridine moieties in thiotepa/tepa are substrates for both GST A1-1 and P1-1. Triethylenephosphoramide 69-73 S100 calcium binding protein A10 Homo sapiens 116-120 7947730-11 1994 (AII)2(p11)2 required less calcium to support membrane binding than did annexin II. Calcium 27-34 S100 calcium binding protein A10 Homo sapiens 7-10 7712478-10 1995 Kms for the GST A1-1 (alpha) and P1-1 (pi) catalyzed formation of monoglutathionyl thiotepa were in the 5-7 mM range. monoglutathionyl thiotepa 66-91 S100 calcium binding protein A10 Homo sapiens 33-37 7712478-11 1995 Since the pH in tumors might be lower than in normal cells, the pH dependency of the GST P1-1 catalyzed formation of monoglutathionyl thiotepa was also studied. monoglutathionyl thiotepa 117-142 S100 calcium binding protein A10 Homo sapiens 89-93 7876192-6 1995 Intriguingly, in ICE epsilon amino acids 20-335, which encompass most of the propeptide and the p20 subunit, are deleted resulting in the formation of a molecule that is homologous to the p10 subunit. propeptide 77-87 S100 calcium binding protein A10 Homo sapiens 188-191 7954469-6 1994 In this paper we describe the involvement of purified human glutathione S-transferases isoenzymes GST A1-1, A2-2, M1a-1a, and P1-1 in the formation of two types of glutathionyl conjugates of cyclophosphamide, i.e., 4-glutathionylcyclophosphamide (4-GSCP) and monochloromonoglutathionylphosphoramide mustard. 4-gscp 247-253 S100 calcium binding protein A10 Homo sapiens 126-130 7954469-6 1994 In this paper we describe the involvement of purified human glutathione S-transferases isoenzymes GST A1-1, A2-2, M1a-1a, and P1-1 in the formation of two types of glutathionyl conjugates of cyclophosphamide, i.e., 4-glutathionylcyclophosphamide (4-GSCP) and monochloromonoglutathionylphosphoramide mustard. monochloromonoglutathionylphosphoramide 259-298 S100 calcium binding protein A10 Homo sapiens 126-130 7954469-7 1994 When 0.1 mM 4-hydroxycyclophosphamide and 1 mM GSH was incubated in the presence of 10 microM GST A1-1, A2-2, M1a-1a, and P1-1 the formation of 4-GSCP was 2-4-fold increased above the spontaneous level. 4-hydroxycyclophosphamide 12-37 S100 calcium binding protein A10 Homo sapiens 122-126 7954469-7 1994 When 0.1 mM 4-hydroxycyclophosphamide and 1 mM GSH was incubated in the presence of 10 microM GST A1-1, A2-2, M1a-1a, and P1-1 the formation of 4-GSCP was 2-4-fold increased above the spontaneous level. Glutathione 47-50 S100 calcium binding protein A10 Homo sapiens 122-126 7954469-7 1994 When 0.1 mM 4-hydroxycyclophosphamide and 1 mM GSH was incubated in the presence of 10 microM GST A1-1, A2-2, M1a-1a, and P1-1 the formation of 4-GSCP was 2-4-fold increased above the spontaneous level. 4-gscp 144-150 S100 calcium binding protein A10 Homo sapiens 122-126 7954469-6 1994 In this paper we describe the involvement of purified human glutathione S-transferases isoenzymes GST A1-1, A2-2, M1a-1a, and P1-1 in the formation of two types of glutathionyl conjugates of cyclophosphamide, i.e., 4-glutathionylcyclophosphamide (4-GSCP) and monochloromonoglutathionylphosphoramide mustard. glutathionyl 164-176 S100 calcium binding protein A10 Homo sapiens 126-130 7954469-6 1994 In this paper we describe the involvement of purified human glutathione S-transferases isoenzymes GST A1-1, A2-2, M1a-1a, and P1-1 in the formation of two types of glutathionyl conjugates of cyclophosphamide, i.e., 4-glutathionylcyclophosphamide (4-GSCP) and monochloromonoglutathionylphosphoramide mustard. Cyclophosphamide 191-207 S100 calcium binding protein A10 Homo sapiens 126-130 7954469-6 1994 In this paper we describe the involvement of purified human glutathione S-transferases isoenzymes GST A1-1, A2-2, M1a-1a, and P1-1 in the formation of two types of glutathionyl conjugates of cyclophosphamide, i.e., 4-glutathionylcyclophosphamide (4-GSCP) and monochloromonoglutathionylphosphoramide mustard. 4-glutathionylcyclophosphamide 215-245 S100 calcium binding protein A10 Homo sapiens 126-130 7932743-1 1994 The crystal structure of class Pi glutathione S-transferase from porcine lung (pGST P1-1) in complex with glutathione sulphonate has been refined at 2.11 A resolution, to a crystallographic R-factor of 16.5% for 21, 165 unique reflections. glutathione sulphonate 106-128 S100 calcium binding protein A10 Homo sapiens 84-88 8069855-8 1994 Both of these parameters, as well as the cellular content of the substrate 5-methyltetrahydrofolate, and the cofactor methylcobalamin, in addition to adenosylcobalamin, were high in P10, declined progressively in P45 and P60, and were restored in P60R. 5-methyltetrahydrofolate 75-99 S100 calcium binding protein A10 Homo sapiens 182-185 8490575-1 1993 The binding of annexin II (p36) and of its complex ((p36)2 (p11)2) to model phospholipid vesicles led to conformational changes of the proteins which were studied by fluorescence spectroscopy. Phospholipids 76-88 S100 calcium binding protein A10 Homo sapiens 60-63 7986458-5 1994 A P10 to P90 (10th and 90th percentile) increase of alcohol intake, as reflected by serum gamma-glutamyltransferase, was associated with a 3.2 +/- 0.9 mm Hg higher DBP in men and with a 3.1 +/- 1.6 mm Hg higher SBP and a 1.5 +/- 0.8 mm Hg higher DBP in women. Alcohols 52-59 S100 calcium binding protein A10 Homo sapiens 2-5 8044845-2 1994 The crystal structure at 2.5 A resolution of a recombinant human ICE-tetrapeptide chloromethylketone complex reveals that the holoenzyme is a homodimer of catalytic domains, each of which contains a p20 and a p10 subunit. chloromethylketone 82-100 S100 calcium binding protein A10 Homo sapiens 209-212 8069231-0 1994 Inhibition of human placenta glutathione transferase P1-1 by calvatic acid. calvatic acid 61-74 S100 calcium binding protein A10 Homo sapiens 53-57 8142254-4 1994 P1 and P10 were later shown by chemical and mass spectral studies to be carboxylic acids. Carboxylic Acids 72-88 S100 calcium binding protein A10 Homo sapiens 7-10 8131222-3 1994 About 20% inhibition was observed for GST A2-2 and P1-1, using 0.5 mM of both 5-GSDA and 5-GSMDOPA. 5-S-glutathionyldopamine 78-84 S100 calcium binding protein A10 Homo sapiens 51-55 8131222-3 1994 About 20% inhibition was observed for GST A2-2 and P1-1, using 0.5 mM of both 5-GSDA and 5-GSMDOPA. 5-S-glutathionyl-alpha-methyldopa 89-98 S100 calcium binding protein A10 Homo sapiens 51-55 1633809-11 1992 In p11, a different member of the S100 family, the C-terminal extension which contains a corresponding cysteine (Cys82 in p11), is involved in a Ca(2+)-independent complex formation with the protein ligand annexin II. Cysteine 103-111 S100 calcium binding protein A10 Homo sapiens 3-6 8433366-5 1993 For the exon ligation reaction, the specification of the 3" splice site is thought to be influenced by the 3" exon-IGS pairing P10 and three structural elements in the intron: the universally conserved guanosine residue preceding the 3" splice site, the long-range pairing P9.0, and the triple stem-loop region composed of P9, P9.1 and P9.2. Guanosine 202-211 S100 calcium binding protein A10 Homo sapiens 127-130 8429832-3 1993 The cleavage of Ii to p21 and p10 was revealed in leupeptin-treated cells. leupeptin 50-59 S100 calcium binding protein A10 Homo sapiens 30-33 8429832-4 1993 Cell treatment with Brefeldin A (BFA) was associated with a decrease in Ii-freed alpha, beta dimers, with inhibition of leupeptin-revealed cleavage of Ii to p21 and p10, and with persistence of endoglycosidase H susceptibility of Ii and class II alpha, beta chains. Brefeldin A 20-31 S100 calcium binding protein A10 Homo sapiens 165-168 1380097-8 1992 Since the sequential order of the viral proteins in the Gag precursor is p10-pp21-p27-p14 and that in Gag-Pro is p10-pp21-p27-p30-protease, our results demonstrate the radial organization of the polypeptide precursors forming the intracytoplasmic A particles. Glycosaminoglycans 56-59 S100 calcium binding protein A10 Homo sapiens 73-76 1380097-8 1992 Since the sequential order of the viral proteins in the Gag precursor is p10-pp21-p27-p14 and that in Gag-Pro is p10-pp21-p27-p30-protease, our results demonstrate the radial organization of the polypeptide precursors forming the intracytoplasmic A particles. gag-pro 102-109 S100 calcium binding protein A10 Homo sapiens 113-116 8442764-2 1993 [14C]Ethacrynic acid, 0.8 nmol/nmol human P1-1 and 0.8 nmol/nmol rat GST 7-7 could be incorporated, resulting in 65-93% inhibition of the activity towards 1-chloro-2,4-dinitrobenzene (CDNB). Carbon-14 0-5 S100 calcium binding protein A10 Homo sapiens 42-52 8442764-2 1993 [14C]Ethacrynic acid, 0.8 nmol/nmol human P1-1 and 0.8 nmol/nmol rat GST 7-7 could be incorporated, resulting in 65-93% inhibition of the activity towards 1-chloro-2,4-dinitrobenzene (CDNB). Ethacrynic Acid 5-20 S100 calcium binding protein A10 Homo sapiens 42-52 8442764-2 1993 [14C]Ethacrynic acid, 0.8 nmol/nmol human P1-1 and 0.8 nmol/nmol rat GST 7-7 could be incorporated, resulting in 65-93% inhibition of the activity towards 1-chloro-2,4-dinitrobenzene (CDNB). Dinitrochlorobenzene 155-182 S100 calcium binding protein A10 Homo sapiens 42-52 8442764-2 1993 [14C]Ethacrynic acid, 0.8 nmol/nmol human P1-1 and 0.8 nmol/nmol rat GST 7-7 could be incorporated, resulting in 65-93% inhibition of the activity towards 1-chloro-2,4-dinitrobenzene (CDNB). Dinitrochlorobenzene 184-188 S100 calcium binding protein A10 Homo sapiens 42-52 8429832-4 1993 Cell treatment with Brefeldin A (BFA) was associated with a decrease in Ii-freed alpha, beta dimers, with inhibition of leupeptin-revealed cleavage of Ii to p21 and p10, and with persistence of endoglycosidase H susceptibility of Ii and class II alpha, beta chains. Brefeldin A 33-36 S100 calcium binding protein A10 Homo sapiens 165-168 8503790-3 1993 To map the gene encoding protein p10, a mixture of 20-mer oligonucleotides based upon a part of the amino acid sequence was hybridized to cloned ASF virus restriction fragments. Oligonucleotides 58-74 S100 calcium binding protein A10 Homo sapiens 33-36 7968818-7 1993 A level of HDL cholesterol below P10 may be considered as dangerous for boys below 1.00 mmol/l and for girls below 1.11 mmol/l. Cholesterol 15-26 S100 calcium binding protein A10 Homo sapiens 33-36 1637329-0 1992 Contribution of five amino acid residues in the glutathione-binding site to the function of human glutathione transferase P1-1. Glutathione 48-59 S100 calcium binding protein A10 Homo sapiens 122-126 1637329-1 1992 Five amino acids in proximity to GSH bound in the active-site cavity of human Class Pi glutathione transferase (GST) P1-1 were mutated by oligonucleotide-directed site-specific mutagenesis. Glutathione 33-36 S100 calcium binding protein A10 Homo sapiens 117-121 1637329-1 1992 Five amino acids in proximity to GSH bound in the active-site cavity of human Class Pi glutathione transferase (GST) P1-1 were mutated by oligonucleotide-directed site-specific mutagenesis. Oligonucleotides 138-153 S100 calcium binding protein A10 Homo sapiens 117-121 1637343-0 1992 Participation of the phenolic hydroxyl group of Tyr-8 in the catalytic mechanism of human glutathione transferase P1-1. Tyrosine 48-51 S100 calcium binding protein A10 Homo sapiens 114-118 1633809-11 1992 In p11, a different member of the S100 family, the C-terminal extension which contains a corresponding cysteine (Cys82 in p11), is involved in a Ca(2+)-independent complex formation with the protein ligand annexin II. Cysteine 103-111 S100 calcium binding protein A10 Homo sapiens 122-125 1637343-15 1992 The results indicate that the phenolic hydroxyl group of Tyr-8 in un-ionized form, but not the phenolate of Tyr-8, contributes to catalysis by glutathione transferase P1-1. Tyrosine 57-60 S100 calcium binding protein A10 Homo sapiens 167-171 2143760-0 1990 Alkylation of cysteine 82 of p11 abolishes the complex formation with the tyrosine-protein kinase substrate p36 (annexin 2, calpactin 1, lipocortin 2). Cysteine 14-22 S100 calcium binding protein A10 Homo sapiens 29-32 1658378-4 1991 The gag precursor is now mapped as NH2-MA(p10)-p4-CA(p24)-NC(p12)-COOH. Glycosaminoglycans 4-7 S100 calcium binding protein A10 Homo sapiens 42-45 1658378-4 1991 The gag precursor is now mapped as NH2-MA(p10)-p4-CA(p24)-NC(p12)-COOH. Carbonic Acid 66-70 S100 calcium binding protein A10 Homo sapiens 42-45 2200887-1 1990 To obtain a better understanding of the role of the gag gene-encoded matrix (MA) protein in the assembly and maturation of type D retroviruses, we have made five mutants with specific in-frame deletions within the p10-coding region by the use of oligonucleotide-directed mutagenesis. Glycosaminoglycans 52-55 S100 calcium binding protein A10 Homo sapiens 214-217 2143760-0 1990 Alkylation of cysteine 82 of p11 abolishes the complex formation with the tyrosine-protein kinase substrate p36 (annexin 2, calpactin 1, lipocortin 2). lipocortin 2 137-149 S100 calcium binding protein A10 Homo sapiens 29-32 2143760-0 1990 Alkylation of cysteine 82 of p11 abolishes the complex formation with the tyrosine-protein kinase substrate p36 (annexin 2, calpactin 1, lipocortin 2). calpactin 1 124-135 S100 calcium binding protein A10 Homo sapiens 29-32 2143760-3 1990 Upon mild cysteine modification conditions, both cysteines (position 61 and 82) of the free p11 become substituted, and the ability to form the p36.p11 complex is lost. Cysteine 10-18 S100 calcium binding protein A10 Homo sapiens 92-95 2143760-3 1990 Upon mild cysteine modification conditions, both cysteines (position 61 and 82) of the free p11 become substituted, and the ability to form the p36.p11 complex is lost. Cysteine 10-18 S100 calcium binding protein A10 Homo sapiens 148-151 2143760-3 1990 Upon mild cysteine modification conditions, both cysteines (position 61 and 82) of the free p11 become substituted, and the ability to form the p36.p11 complex is lost. Cysteine 49-58 S100 calcium binding protein A10 Homo sapiens 92-95 34830395-5 2021 Using our method to measure ASC, stimulation of PBMC with lipopolysaccharide and nigericin or adenosine triphosphate resulted in microscopic identification of intracellular ASC specks, as well as interleukin 1 (IL-1) beta and caspase-1 p10 in the periphery. Nigericin 81-90 S100 calcium binding protein A10 Homo sapiens 236-239 2143760-4 1990 Under the same conditions, the 2 cysteines of p11 incorporated into the complex display differential reactivity. Cysteine 33-42 S100 calcium binding protein A10 Homo sapiens 46-49 2143760-6 1990 p11 derivatives substituted only on cysteine 61 retain binding activity for p36 unless cysteine 82 is substituted by a second cycle of modification of the isolated p11. Cysteine 36-44 S100 calcium binding protein A10 Homo sapiens 0-3 2143760-6 1990 p11 derivatives substituted only on cysteine 61 retain binding activity for p36 unless cysteine 82 is substituted by a second cycle of modification of the isolated p11. Cysteine 87-95 S100 calcium binding protein A10 Homo sapiens 0-3 2165389-1 1990 The uptake and intracellular metabolism of 4-(1-pyrene)butanoic acid (P4), 10-(1-pyrene)decanoic acid (P10) and 12-(1-pyrene)dodecanoic acid (P12) were investigated in cultured lymphoid cell lines from normal individuals and from a patient with multisystemic lipid storage myopathy (MLSM). 10-(1-pyrene)decanoic acid 75-101 S100 calcium binding protein A10 Homo sapiens 103-106 2165389-6 1990 After a 24 h incubation in the presence of P10 or P12, at any concentration, the fluorescent triacylglycerol content of MLSM cells was 2-5-fold higher than that of control cells. Triglycerides 93-108 S100 calcium binding protein A10 Homo sapiens 43-46 2165389-8 1990 This cytotoxicity was dependent on the fluorescent-fatty-acid chain length (P12 greater than P10 greater than P4). Fatty Acids 51-61 S100 calcium binding protein A10 Homo sapiens 93-96 2165389-9 1990 Pulse-chase experiments permitted one to demonstrate the defect in the degradation of endogenously biosynthesized triacylglycerols in MLSM cells (residual activity was around 10-25% of controls on the basis of half-lives and initial rates of P10- or P12-labelled-triacylglycerol catabolism); MLSM lymphoid cells exhibited a mild phenotypic expression of the lipid storage (less severe than that observed in fibroblasts). Triglycerides 114-130 S100 calcium binding protein A10 Homo sapiens 242-245 2165389-9 1990 Pulse-chase experiments permitted one to demonstrate the defect in the degradation of endogenously biosynthesized triacylglycerols in MLSM cells (residual activity was around 10-25% of controls on the basis of half-lives and initial rates of P10- or P12-labelled-triacylglycerol catabolism); MLSM lymphoid cells exhibited a mild phenotypic expression of the lipid storage (less severe than that observed in fibroblasts). Triglycerides 114-129 S100 calcium binding protein A10 Homo sapiens 242-245 34830395-5 2021 Using our method to measure ASC, stimulation of PBMC with lipopolysaccharide and nigericin or adenosine triphosphate resulted in microscopic identification of intracellular ASC specks, as well as interleukin 1 (IL-1) beta and caspase-1 p10 in the periphery. Adenosine 94-103 S100 calcium binding protein A10 Homo sapiens 236-239 34485305-12 2021 Clinically, the higher expression of S100A4 and S100A10 were significantly linked to shorter progression free survival in patients receiving carfilzomib-based therapy. carfilzomib 141-152 S100 calcium binding protein A10 Homo sapiens 48-55 34787893-7 2021 Knockdown of S100A10 effectively counteracted TNF-alpha-induced ROS level, apoptosis, and calcium level and associated with decreased inflammation-related metalloproteinase 1 (MMP1), MMP13, and nuclear necrosis factor-kappa B (NF-kappaB)-p65 and increased survivin and cytoplasmic NF-kappaB-p65. ros 64-67 S100 calcium binding protein A10 Homo sapiens 13-20 34787893-7 2021 Knockdown of S100A10 effectively counteracted TNF-alpha-induced ROS level, apoptosis, and calcium level and associated with decreased inflammation-related metalloproteinase 1 (MMP1), MMP13, and nuclear necrosis factor-kappa B (NF-kappaB)-p65 and increased survivin and cytoplasmic NF-kappaB-p65. Calcium 90-97 S100 calcium binding protein A10 Homo sapiens 13-20 34787893-8 2021 Overexpression of S100A10 had an effect similar to TNF-alpha,which was significantly counteracted by pyrrolidine dithiocarbamate, an NF-kappaB inhibitor, or verapamil, a calcium-channel blocker. pyrrolidine dithiocarbamic acid 101-128 S100 calcium binding protein A10 Homo sapiens 18-25 34787893-8 2021 Overexpression of S100A10 had an effect similar to TNF-alpha,which was significantly counteracted by pyrrolidine dithiocarbamate, an NF-kappaB inhibitor, or verapamil, a calcium-channel blocker. Verapamil 157-166 S100 calcium binding protein A10 Homo sapiens 18-25 34787893-8 2021 Overexpression of S100A10 had an effect similar to TNF-alpha,which was significantly counteracted by pyrrolidine dithiocarbamate, an NF-kappaB inhibitor, or verapamil, a calcium-channel blocker. Calcium 170-177 S100 calcium binding protein A10 Homo sapiens 18-25 34206694-7 2021 The latent heat and energy storage efficiency of PEG in the P-10-MCC sample are 152.5 J/g and 96.48%, respectively, which are significantly higher than those of comparable materials. Polyethylene Glycol 6000 49-52 S100 calcium binding protein A10 Homo sapiens 60-68 34336846-9 2021 Cell functional experiments, co-immunoprecipitation, MG132 and ginkgolic acid treatment, western blot, and ChIP-Seq were used to identify the mechanism of S100A10 nuclear location. benzyloxycarbonylleucyl-leucyl-leucine aldehyde 53-58 S100 calcium binding protein A10 Homo sapiens 155-162 34336846-9 2021 Cell functional experiments, co-immunoprecipitation, MG132 and ginkgolic acid treatment, western blot, and ChIP-Seq were used to identify the mechanism of S100A10 nuclear location. ginkgolic acid 63-77 S100 calcium binding protein A10 Homo sapiens 155-162 34356598-4 2021 Additionally, S100A10 interacts with 5-hydroxytryptamine 1B (5-HT1B) receptor, which influences neurotransmitter binding and, through that, depressive symptoms. Serotonin 37-56 S100 calcium binding protein A10 Homo sapiens 14-21 34206694-9 2021 The combined mesoporous and macro-porous structure of P-10-MCC is critical to retaining a large amount of PEG within the matrix, resulting in a high latent heat in the operating temperature range of 35-57 C. The P-10MCC sample also demonstrates a high energy storage capacity (98.59%), high thermal energy storage/release rates, and exceptional shape-stabilized PCM properties. mesoporous 13-23 S100 calcium binding protein A10 Homo sapiens 54-62 34206694-9 2021 The combined mesoporous and macro-porous structure of P-10-MCC is critical to retaining a large amount of PEG within the matrix, resulting in a high latent heat in the operating temperature range of 35-57 C. The P-10MCC sample also demonstrates a high energy storage capacity (98.59%), high thermal energy storage/release rates, and exceptional shape-stabilized PCM properties. Polyethylene Glycol 6000 106-109 S100 calcium binding protein A10 Homo sapiens 54-62 34091446-13 2021 Anti-Der p 10 could be a possible biomarker of clinical relevance to shrimp sensitization and could reduce the need for OCTs. maxacalcitol 120-124 S100 calcium binding protein A10 Homo sapiens 9-13 34073084-4 2021 Its identification as a complex with SLCO2A1 as a core pore-forming component and two auxiliary regulatory proteins, annexin A2 and S100A10 (p11), explains the activation mechanism as Tyr23 dephosphorylation at ANXA2 in parallel with calcium binding at S100A10. Calcium 234-241 S100 calcium binding protein A10 Homo sapiens 132-139 34073084-4 2021 Its identification as a complex with SLCO2A1 as a core pore-forming component and two auxiliary regulatory proteins, annexin A2 and S100A10 (p11), explains the activation mechanism as Tyr23 dephosphorylation at ANXA2 in parallel with calcium binding at S100A10. Calcium 234-241 S100 calcium binding protein A10 Homo sapiens 141-144 34073084-4 2021 Its identification as a complex with SLCO2A1 as a core pore-forming component and two auxiliary regulatory proteins, annexin A2 and S100A10 (p11), explains the activation mechanism as Tyr23 dephosphorylation at ANXA2 in parallel with calcium binding at S100A10. Calcium 234-241 S100 calcium binding protein A10 Homo sapiens 253-260 35390696-0 2022 Identification of putative binding interface of PI(3,5)P2 lipid on rice black-streaked dwarf virus (RBSDV) P10 protein. pi(3,5)p2 lipid 48-63 S100 calcium binding protein A10 Homo sapiens 107-110 35092164-7 2022 While blocking the fusion of autophagosomes with lysosomes by bafilomycin A1(BafA1), the reduced NLRP3 inflammasome activity induced by RAPA was significantly restored, with increased protein levels of NLRP3 and cleaved Casp-1(p10), as well as IL-1beta secretion. bafilomycin A1 62-76 S100 calcium binding protein A10 Homo sapiens 227-230 35092164-7 2022 While blocking the fusion of autophagosomes with lysosomes by bafilomycin A1(BafA1), the reduced NLRP3 inflammasome activity induced by RAPA was significantly restored, with increased protein levels of NLRP3 and cleaved Casp-1(p10), as well as IL-1beta secretion. Sirolimus 136-140 S100 calcium binding protein A10 Homo sapiens 227-230 35390696-2 2022 High affinity binding between RBSDV P10 and PI(3,5)P2 lipid layer was measured using biolayer interferometry (BLI). pi(3,5)p2 lipid 44-59 S100 calcium binding protein A10 Homo sapiens 36-39 2510403-5 1989 The predicted polypeptide (P11) contains a cysteine-rich sequence bearing a remarkable similarity to the "zinc finger" sequences found in a number of proteins. Cysteine 43-51 S100 calcium binding protein A10 Homo sapiens 27-30 35567118-4 2022 The ORF5 (p10) protein sequence of eight Iranian isolates was compared to other vitiviruses, showing that the most conserved region resides in the N-terminus, carrying an arginine-rich motif followed by a zinc-finger motif. Arginine 171-179 S100 calcium binding protein A10 Homo sapiens 10-13 35217896-2 2022 In the current study, the involvement of S100 calcium binding protein S100A4, S100A9, and S100A10 in the inflammatory settings of COVID-19 patients were evaluated. Calcium 46-53 S100 calcium binding protein A10 Homo sapiens 90-97 3196738-1 1988 Fluorescent triacylglycerols containing pyrenedecanoic (P10) and pyrenebutanoic (P4) acids were synthesized and their hydrolysis by lipases from human gastric juice and stomach homogenate was investigated. Triglycerides 12-28 S100 calcium binding protein A10 Homo sapiens 56-59 2550076-2 1989 The metabolism of the triacylglycerols has been investigated in this lymphoid cell line from multisystemic lipid storage myopathy as well as in control cells through pulse-chase experiments using 10-(1-pyrene)decanoic acid (P10), a fluorescent fatty acid derivative, as precursor. Triglycerides 22-38 S100 calcium binding protein A10 Homo sapiens 224-227 2550076-5 1989 After 24 h incubation, at any extracellular concentration of P10, the content of P10-labelled triacylglycerols was much higher in multisystemic lipid storage myopathy cells than in controls. Triglycerides 94-110 S100 calcium binding protein A10 Homo sapiens 61-64 2550076-5 1989 After 24 h incubation, at any extracellular concentration of P10, the content of P10-labelled triacylglycerols was much higher in multisystemic lipid storage myopathy cells than in controls. Triglycerides 94-110 S100 calcium binding protein A10 Homo sapiens 81-84 2550076-6 1989 Chase experiments showed an impairment in the rate of degradation of biosynthesized triacylglycerols in multisystemic lipid storage myopathy lymphoblasts compared to controls with time of chase (the ratio P10-triacylglycerols/P10-phospholipids increased in mutant cells while it decreased in normal cells). Triglycerides 84-100 S100 calcium binding protein A10 Homo sapiens 205-208 3196738-1 1988 Fluorescent triacylglycerols containing pyrenedecanoic (P10) and pyrenebutanoic (P4) acids were synthesized and their hydrolysis by lipases from human gastric juice and stomach homogenate was investigated. pyrenedecanoic 40-54 S100 calcium binding protein A10 Homo sapiens 56-59 2973411-3 1988 Here we have characterized the p11 binding site on p36 by fluorescence spectroscopy using porcine p36 labelled at cysteine 8 with the fluorophore Prodan (6-proprionyl-2-dimethylamino-naphthalene). prodan 146-152 S100 calcium binding protein A10 Homo sapiens 31-34 2973411-3 1988 Here we have characterized the p11 binding site on p36 by fluorescence spectroscopy using porcine p36 labelled at cysteine 8 with the fluorophore Prodan (6-proprionyl-2-dimethylamino-naphthalene). Cysteine 114-122 S100 calcium binding protein A10 Homo sapiens 31-34 2973411-3 1988 Here we have characterized the p11 binding site on p36 by fluorescence spectroscopy using porcine p36 labelled at cysteine 8 with the fluorophore Prodan (6-proprionyl-2-dimethylamino-naphthalene). 6-proprionyl-2-dimethylamino-naphthalene 154-194 S100 calcium binding protein A10 Homo sapiens 31-34 3395272-5 1988 Nine apo B-100 hydrophilic peptides, 12 to 26 amino acids long, were selected, and three were found to interact with the agarose-bound CSPG: apo B P-1 (LRKHKLIDVISMYRELLKDLSKEA, residues 4230 to 4254), apo B P-2 (RLTRKRGLKLATALSLSNK, residues 3359 to 3377), and apo B P-11 (RQVSHAKEKLTALTKK, residues 2106 to 2121). Sepharose 121-128 S100 calcium binding protein A10 Homo sapiens 268-272 3402455-8 1988 Iodinated osteonectin, previously incubated with purified thrombospondin, specifically bound to an anti-thrombospondin monoclonal antibody (P10) linked to protein-A--Sepharose 4B. Sepharose 166-175 S100 calcium binding protein A10 Homo sapiens 140-143 2435721-1 1987 We have studied the interactions of single-stranded polyribonucleotides with murine leukemia virus structural proteins p10, p10" (a p10 variant), and Pr65gag, as well as Rous sarcoma virus (RSV) pp12 (a p10 analog). Polyribonucleotides 52-71 S100 calcium binding protein A10 Homo sapiens 119-122 3139081-4 1988 A possible relationship between protein p10 phosphorylation and RNA synthesis in vitro by the virion-associated RNA polymerase is suggested by the finding that N-alpha-tosyl-L-lysyl-chloromethyl ketone inhibited both phosphorylation of p10 and transcription. n-alpha-tosyl-l-lysyl-chloromethyl ketone 160-201 S100 calcium binding protein A10 Homo sapiens 40-43 3139081-4 1988 A possible relationship between protein p10 phosphorylation and RNA synthesis in vitro by the virion-associated RNA polymerase is suggested by the finding that N-alpha-tosyl-L-lysyl-chloromethyl ketone inhibited both phosphorylation of p10 and transcription. n-alpha-tosyl-l-lysyl-chloromethyl ketone 160-201 S100 calcium binding protein A10 Homo sapiens 236-239 3405210-7 1988 They belong to a novel subfamily of highly homologous calcium-binding proteins which includes S100 alpha, S100 beta, intestinal calcium-binding protein, P11, and calcyclin (2A9). Calcium 54-61 S100 calcium binding protein A10 Homo sapiens 153-156 2435721-1 1987 We have studied the interactions of single-stranded polyribonucleotides with murine leukemia virus structural proteins p10, p10" (a p10 variant), and Pr65gag, as well as Rous sarcoma virus (RSV) pp12 (a p10 analog). Polyribonucleotides 52-71 S100 calcium binding protein A10 Homo sapiens 124-127 2435721-1 1987 We have studied the interactions of single-stranded polyribonucleotides with murine leukemia virus structural proteins p10, p10" (a p10 variant), and Pr65gag, as well as Rous sarcoma virus (RSV) pp12 (a p10 analog). Polyribonucleotides 52-71 S100 calcium binding protein A10 Homo sapiens 124-127 2435721-1 1987 We have studied the interactions of single-stranded polyribonucleotides with murine leukemia virus structural proteins p10, p10" (a p10 variant), and Pr65gag, as well as Rous sarcoma virus (RSV) pp12 (a p10 analog). Polyribonucleotides 52-71 S100 calcium binding protein A10 Homo sapiens 124-127 2435721-5 1987 Addition of NaCl to fully titrated MuLV p10-nucleic acid mixtures effected nearly complete restoration of poly(epsilon A) or MuLV p10 fluorescence. Sodium Chloride 12-16 S100 calcium binding protein A10 Homo sapiens 40-43 2435721-5 1987 Addition of NaCl to fully titrated MuLV p10-nucleic acid mixtures effected nearly complete restoration of poly(epsilon A) or MuLV p10 fluorescence. Sodium Chloride 12-16 S100 calcium binding protein A10 Homo sapiens 130-133 2435721-6 1987 Under conditions of 0.06 M NaCl, p10 bound noncooperatively to poly(epsilon A) with an intrinsic association constant, K = 2.3 X 10(6) M-1. Sodium Chloride 27-31 S100 calcium binding protein A10 Homo sapiens 33-36 2435721-8 1987 Chemical modifications of the p10 cysteine residues did not alter the affinity for poly(epsilon A). Cysteine 34-42 S100 calcium binding protein A10 Homo sapiens 30-33 3030438-1 1987 Cholesteryl esters with various chain lengths of fatty acid, radioactive (C2-C18:1) and fluorescent (pyrene butanoic and decanoic acid, P4 and P10, respectively) were synthesized and their hydrolysis was investigated in lymphoid cell lines from normal subjects and from Wolman"s disease patients. Cholesterol Esters 0-18 S100 calcium binding protein A10 Homo sapiens 143-146 3030438-2 1987 The comparison of their hydrolysis showed that three cholesterol esterases were present in normal lymphoid cell lines: the first, active at pH 4.0, hydrolysed preferentially cholesteryl esters of acyl chain length more than 8 carbons, and P10-cholesteryl ester. Cholesterol 53-64 S100 calcium binding protein A10 Homo sapiens 239-242 2417838-9 1986 Investigation of tryptic peptide fragments of thrombospondin isolated by fast protein liquid chromatography showed that 125I-labelled antibody P10 bound to 400-kDa and 120-kDa fragments whereas 125I-labelled P12 only recognized a 400-kDa fragment. Peptides 25-32 S100 calcium binding protein A10 Homo sapiens 143-146 2951248-0 1986 Functionally distinct serine phosphorylation sites of p36, the cellular substrate of retroviral protein kinase; differential inhibition of reassociation with p11. Serine 22-28 S100 calcium binding protein A10 Homo sapiens 158-161 2417838-7 1986 When P10 and P12 were incubated with 125I-labelled platelet releasates treated for 48 h at 4 degrees C with 10mM EDTA, three major protein bands (160, 146 and 130 kDa) were immunoprecipitated in addition to the minor bands mentioned above. Edetic Acid 113-117 S100 calcium binding protein A10 Homo sapiens 5-8 3485855-7 1986 Myristic acid-labeled virions contained a single radioactive protein, p10, supporting the mapping of this molecule to the amino terminus. Myristic Acid 0-13 S100 calcium binding protein A10 Homo sapiens 70-73 2417838-12 1986 The haemagglutination activity of EDTA-treated thrombospondin was inhibited by P10 and enhanced by P12. Edetic Acid 34-38 S100 calcium binding protein A10 Homo sapiens 79-82 2993659-5 1985 This implies the existence of a sixth gag protein 22 amino acids in length and located between p19 and p10 on the gag precursor. Glycosaminoglycans 38-41 S100 calcium binding protein A10 Homo sapiens 103-106 6328019-5 1984 The nucleotide sequence predicts the order of amino acids in each of the individual gag-coded proteins (p15, p12, p30, p10), all of which derive from the gag gene precursor. Glycosaminoglycans 84-87 S100 calcium binding protein A10 Homo sapiens 119-122 3927012-5 1985 The p10 proteins from the two viruses have similar amino acid compositions, and both are blocked to N-terminal Edman degradation. edman 111-116 S100 calcium binding protein A10 Homo sapiens 4-7 3857117-3 1985 The activities coelute on Bio-Gel P-10 in acetic acid, but can be completely separated by reverse-phase high-pressure liquid chromatography. Acetic Acid 42-53 S100 calcium binding protein A10 Homo sapiens 34-38 2982497-3 1985 We map the activity to an alternate reading frame in the p19-p10 region of the gag gene and identify a mRNA whose spliced structure would direct translation of this reading frame from the Pr76gag initiation codon. Glycosaminoglycans 79-82 S100 calcium binding protein A10 Homo sapiens 61-64 6328019-5 1984 The nucleotide sequence predicts the order of amino acids in each of the individual gag-coded proteins (p15, p12, p30, p10), all of which derive from the gag gene precursor. Glycosaminoglycans 154-157 S100 calcium binding protein A10 Homo sapiens 119-122 6225467-6 1983 Analysis of the scission products on Bio-Gel P-10 yielded fragments varying in size from single disaccharides to glycans consisting of nine disaccharide units. Disaccharides 96-109 S100 calcium binding protein A10 Homo sapiens 45-49 6225467-6 1983 Analysis of the scission products on Bio-Gel P-10 yielded fragments varying in size from single disaccharides to glycans consisting of nine disaccharide units. Polysaccharides 113-120 S100 calcium binding protein A10 Homo sapiens 45-49 6225467-6 1983 Analysis of the scission products on Bio-Gel P-10 yielded fragments varying in size from single disaccharides to glycans consisting of nine disaccharide units. Disaccharides 96-108 S100 calcium binding protein A10 Homo sapiens 45-49 7161366-1 1982 A new assay method is described for the simultaneous determination of free 3-methoxy-4-hydroxymandelic acid and 3-methoxy-4-hydroxyphenylethyleneglycol in plasma utilizing separation and purification by Bio-Gel P-10 followed by high-performance liquid chromatography with electrochemical detection. 3-methoxy-4-hydroxymandelic acid 75-107 S100 calcium binding protein A10 Homo sapiens 211-215 6626500-1 1983 Kinetic evidence for involvement of aspartic acid at position P10. Aspartic Acid 36-49 S100 calcium binding protein A10 Homo sapiens 62-65 6626500-3 1983 The Michaelis-Menten parameters for the hydrolysis of the Arg-Gly bond in F-8 by thrombin were determined to be Kcat = 31 X 10(-11) M [(NIH unit/L) s]-1 and KM = 310 X 10(-6) M. Comparison of these values with those determined previously for native fibrinogen and for a series of similar synthetic peptides, together with information about the amino acid sequences of this portion of the A alpha chain of abnormal fibrinogens, suggests an important role for Asp at position P10. Arginine 58-61 S100 calcium binding protein A10 Homo sapiens 474-477 6626500-3 1983 The Michaelis-Menten parameters for the hydrolysis of the Arg-Gly bond in F-8 by thrombin were determined to be Kcat = 31 X 10(-11) M [(NIH unit/L) s]-1 and KM = 310 X 10(-6) M. Comparison of these values with those determined previously for native fibrinogen and for a series of similar synthetic peptides, together with information about the amino acid sequences of this portion of the A alpha chain of abnormal fibrinogens, suggests an important role for Asp at position P10. Glycine 62-65 S100 calcium binding protein A10 Homo sapiens 474-477 6300442-1 1983 We have identified p10 as a fifth gag protein of avian sarcoma and leukemia viruses. Glycosaminoglycans 34-37 S100 calcium binding protein A10 Homo sapiens 19-22 6286372-11 1982 The results hav allowed us to conclude that the arrangement of the gag proteins in the Pr76gag is N-p19-(p10? Glycosaminoglycans 67-70 S100 calcium binding protein A10 Homo sapiens 105-108 7309731-7 1981 The sialic acid profile on Bio-Gel P-10 chromatography, following alkaline borohydride degradation, showed the presence of both keratan sulfate and oligosaccharide chains. N-Acetylneuraminic Acid 4-15 S100 calcium binding protein A10 Homo sapiens 35-39 7309731-7 1981 The sialic acid profile on Bio-Gel P-10 chromatography, following alkaline borohydride degradation, showed the presence of both keratan sulfate and oligosaccharide chains. Keratan Sulfate 128-143 S100 calcium binding protein A10 Homo sapiens 35-39 7309731-7 1981 The sialic acid profile on Bio-Gel P-10 chromatography, following alkaline borohydride degradation, showed the presence of both keratan sulfate and oligosaccharide chains. Oligosaccharides 148-163 S100 calcium binding protein A10 Homo sapiens 35-39 574371-0 1979 Isolation and nature of intracellular alpha-aminoadipic acid-containing peptides from Paecilomyces persicinus P-10. 2-Aminoadipic Acid 38-60 S100 calcium binding protein A10 Homo sapiens 110-114 229066-2 1979 Polypeptide VII of cytochrome c oxidase was isolated and purified by gel filtration on Bio-Gel P-10 in 10% acetic acid. Acetic Acid 107-118 S100 calcium binding protein A10 Homo sapiens 95-99 574371-0 1979 Isolation and nature of intracellular alpha-aminoadipic acid-containing peptides from Paecilomyces persicinus P-10. Peptides 72-80 S100 calcium binding protein A10 Homo sapiens 110-114 574371-1 1979 Small intracellular peptides containing alpha-aminoadipic acid, cysteine, and a valine moiety were obtained from mycelia of Paecilomyces persicinus P-10 by ethanol or trichloroacetic acid extraction. Valine 80-86 S100 calcium binding protein A10 Homo sapiens 148-152 574371-1 1979 Small intracellular peptides containing alpha-aminoadipic acid, cysteine, and a valine moiety were obtained from mycelia of Paecilomyces persicinus P-10 by ethanol or trichloroacetic acid extraction. Ethanol 156-163 S100 calcium binding protein A10 Homo sapiens 148-152 60707-1 1976 The translation product of the gag gene of mammalian type-c- RNA viruses is a 65,000-68,000 molecular weight precursor polypeptide (Pr65) whose cleavage leads to the formation of four virion proteins, p30, p15, p12 and p10. Glycosaminoglycans 31-34 S100 calcium binding protein A10 Homo sapiens 219-222 212589-6 1978 Therefore, tryptic peptide analysis of three proteins, gp52, p28, and p10, can serve to distinguish these three viruses from one another. Peptides 19-26 S100 calcium binding protein A10 Homo sapiens 70-73 1086641-1 1976 A chemically defined medium was developed for the biosynthesis of cephalosporin C by Paecilomyces persicinus Nicot strain P-10. cephalosporin C 66-81 S100 calcium binding protein A10 Homo sapiens 122-126 4136230-5 1974 Rechromatography on 8% agarose was found to be more effective than on 6% agarose or sodium dodecyl sulfate polyacrylamide gel electrophoresis for obtaining the five small polypeptides, especially p11 and p10, in a highly purified form suitable for further analysis and for obtaining more precise estimates of their molecular weights, especially when done by co-chromatography with iodinated standard proteins markers. Sodium Dodecyl Sulfate 84-106 S100 calcium binding protein A10 Homo sapiens 196-199 4136230-5 1974 Rechromatography on 8% agarose was found to be more effective than on 6% agarose or sodium dodecyl sulfate polyacrylamide gel electrophoresis for obtaining the five small polypeptides, especially p11 and p10, in a highly purified form suitable for further analysis and for obtaining more precise estimates of their molecular weights, especially when done by co-chromatography with iodinated standard proteins markers. polyacrylamide 107-121 S100 calcium binding protein A10 Homo sapiens 196-199 4136230-8 1974 Rechromatographed p30, p15, and p11, renatured by removing GuHCl with dialysis, reacted only with their homologous antisera in immunodiffusion analysis, indicating that they are immunologically unrelated. Guanidine 59-64 S100 calcium binding protein A10 Homo sapiens 32-35 33912011-9 2021 We found that systemic DHF treatment after HI significantly increased the expression of the artemin (ARTN) gene and protein at P8 and P10, respectively. dhf 23-26 S100 calcium binding protein A10 Homo sapiens 134-137 34010748-0 2021 P11 (S100A10) as a potential predictor of ketamine response in patients with SSRI-resistant depression. Ketamine 42-50 S100 calcium binding protein A10 Homo sapiens 0-3 34010748-0 2021 P11 (S100A10) as a potential predictor of ketamine response in patients with SSRI-resistant depression. Ketamine 42-50 S100 calcium binding protein A10 Homo sapiens 5-12 34010748-2 2021 P11 has been implicated in ketamine"s mechanism of action and proposed as biomarker for treatment response to other antidepressants. Ketamine 27-35 S100 calcium binding protein A10 Homo sapiens 0-3 34010748-3 2021 This study explores the effect of ketamine on peripheral p11 and the potential role for p11 as response marker for ketamine treatment. Ketamine 34-42 S100 calcium binding protein A10 Homo sapiens 57-60 34010748-6 2021 RESULTS: P11 levels were decreased within the ketamine group in both cytotoxic T cell and T helper cells populations, although this did not significantly differ from changes seen in the placebo group. Ketamine 46-54 S100 calcium binding protein A10 Homo sapiens 9-12 34010748-7 2021 Baseline p11 levels in cytotoxic T cells were significantly correlated with antidepressant response to ketamine treatment. Ketamine 103-111 S100 calcium binding protein A10 Homo sapiens 9-12 34010748-9 2021 CONCLUSIONS: High baseline p11 levels in cytotoxic T cells were associated with a stronger reduction of depressive symptoms in MDD patients after ketamine treatment. Ketamine 146-154 S100 calcium binding protein A10 Homo sapiens 27-30 34010748-10 2021 Future studies should confirm if peripheral p11 levels could be used as a predictor of ketamine treatment response. Ketamine 87-95 S100 calcium binding protein A10 Homo sapiens 44-47 32835655-1 2021 AIIt, a heterotetramer of S100A10 (P11) and Annexin A2, plays a key role in calcium dependent, membrane associations with a variety of proteins. Calcium 76-83 S100 calcium binding protein A10 Homo sapiens 26-33 33223171-0 2021 The transition temperature (42 C) from mesophilic to thermophilic micro-organisms enhances biomethane potential of corn stover. biomethane 92-102 S100 calcium binding protein A10 Homo sapiens 28-33 33223171-2 2021 However, in this study, the effects of temperatures (37, 42, 47, and 55 C) on the biomethane potential of corn stover were conducted with batch experiments, and the highest biomethane potential was at 42 C. biomethane 174-184 S100 calcium binding protein A10 Homo sapiens 202-207 33223171-4 2021 The natural pretreatment stimulated by a slight digestive temperature increase to 42 C can enhance the biomethane potential of corn stover without adding extra acid. biomethane 104-114 S100 calcium binding protein A10 Homo sapiens 82-87 33160379-8 2020 CASE PRESENTATION: In two representative cases of conventional advanced CRC, we immunohistochemically examined S100A10 and ANX A2 expressions in which both TB and PDC were prominent. Terbium 156-158 S100 calcium binding protein A10 Homo sapiens 111-118 32098511-8 2020 Doxofylline inhibits LPS-induced NLRP3-TXNIP inflammasome activation as revealed by its inhibitive effect on NLRP3, caspase 1 (P10 unit), and TXNIP induction as well as weakened induction of IL-1beta and IL-18. doxofylline 0-11 S100 calcium binding protein A10 Homo sapiens 127-130 33160379-14 2020 CONCLUSIONS: During oncogenesis, membranous S100A10 has the potential to be related to TB of CRC. Terbium 87-89 S100 calcium binding protein A10 Homo sapiens 44-51 32427586-4 2020 Paclitaxel induces HIF-1-dependent expression of S100A10, which forms a complex with ANXA2 that interacts with histone chaperone SPT6 and histone demethylase KDM6A. Paclitaxel 0-10 S100 calcium binding protein A10 Homo sapiens 49-56 33224131-7 2020 Colocalization data also showed that the ARV proteins sigmaC, muNS, and p10 prefer to localize to cholesterol-rich lipid raft regions during ARV infection. Cholesterol 98-109 S100 calcium binding protein A10 Homo sapiens 72-75 32801633-10 2020 Loratadine treatment inhibited the expression of TxNIP and several components of the NLRP3 inflammasome complex, including NLRP3, ASC, and cleaved caspase 1 (P10). Loratadine 0-10 S100 calcium binding protein A10 Homo sapiens 158-161 32249647-6 2020 Importantly, treatment with laquinimod significantly inhibited the activation of the NLRP3 inflammasome by reducing the levels of its components, including NLRP3, apoptosis-associated speck-like protein containing a CARD (ASC), and cleaved caspase 1 (P10). laquinimod 28-38 S100 calcium binding protein A10 Homo sapiens 251-254 32616241-6 2020 The results of entropy analysis of the sequences of gag, pol, and env revealed that the env gene had the largest variation, and the gag gene nonconserved sites are mainly concentrated in p19, p10, and p12. Glycosaminoglycans 132-135 S100 calcium binding protein A10 Homo sapiens 192-195 31676250-6 2020 Tim4 overexpression improved the ability of BMDMs and J774A.1 macrophages to produce proinflammatory cytokines and increased the expression of cleaved-caspase-1 (p10) after LPS/ATP stimulation. Adenosine Triphosphate 177-180 S100 calcium binding protein A10 Homo sapiens 162-165 31420581-8 2020 QR showed that the consumption of sodium was positively associated with SBP (P10) and DBP (P10) in males, and positively associated with DBP (P80-P90) alone in females. Sodium 34-40 S100 calcium binding protein A10 Homo sapiens 77-80 31420581-10 2020 Sodium to potassium ratio was positively associated with SBP (P10-P50, P80) and DBP (P70-P90) in males, and was positively associated with SBP(P10-P70, P90) in females. Sodium 0-6 S100 calcium binding protein A10 Homo sapiens 143-146 31420581-10 2020 Sodium to potassium ratio was positively associated with SBP (P10-P50, P80) and DBP (P70-P90) in males, and was positively associated with SBP(P10-P70, P90) in females. Potassium 10-19 S100 calcium binding protein A10 Homo sapiens 62-65 31420581-10 2020 Sodium to potassium ratio was positively associated with SBP (P10-P50, P80) and DBP (P70-P90) in males, and was positively associated with SBP(P10-P70, P90) in females. Potassium 10-19 S100 calcium binding protein A10 Homo sapiens 143-146 31420581-8 2020 QR showed that the consumption of sodium was positively associated with SBP (P10) and DBP (P10) in males, and positively associated with DBP (P80-P90) alone in females. Sodium 34-40 S100 calcium binding protein A10 Homo sapiens 91-94 31420581-9 2020 Intake of potassium was, however, negatively associated with SBP (P20-P30, P70-P80) in males, and also negatively associated with SBP (P10-P80) and DBP(P20-P50) in females. Potassium 10-19 S100 calcium binding protein A10 Homo sapiens 135-138 31420581-10 2020 Sodium to potassium ratio was positively associated with SBP (P10-P50, P80) and DBP (P70-P90) in males, and was positively associated with SBP(P10-P70, P90) in females. Sodium 0-6 S100 calcium binding protein A10 Homo sapiens 62-65 30835642-8 2019 Serum uric acid level was positively correlated with glycan peaks (GP)1, GP2, GP4, GP6, GP10, and GP11, whereas it was negatively correlated with GP12, GP13, GP14, GP15, GP18, and GP20. Uric Acid 6-15 S100 calcium binding protein A10 Homo sapiens 98-102 31431686-3 2020 Here, we demonstrate that S100a10 corticostriatal neurons exhibit distinct serotonin responses and have increased excitability, compared with S100a10-negative neurons. Serotonin 75-84 S100 calcium binding protein A10 Homo sapiens 26-33 31431686-5 2020 We identify cell-type-specific transcriptional signatures in S100a10 neurons that contribute to serotonin responses and strongly associate with psychomotor and somatosensory function. Serotonin 96-105 S100 calcium binding protein A10 Homo sapiens 61-68 31949486-1 2020 S100A10 is a small molecular weight protein expressed in the cytoplasm of many cells and one of the members of the S100 protein family that binds calcium and forms the largest subgroup of EF-hand proteins. Calcium 146-153 S100 calcium binding protein A10 Homo sapiens 0-7 31949486-6 2020 In non-tumor diseases, the distribution of S100A10 in the brain and its interaction with 5-hydroxytryptamine 1B (5-HT1B) receptor, an important mediator in the central nervous system that maintains a dynamic balance of the neurotransmitters, correlates with depression-like behavior. Serotonin 89-111 S100 calcium binding protein A10 Homo sapiens 43-50 31949486-6 2020 In non-tumor diseases, the distribution of S100A10 in the brain and its interaction with 5-hydroxytryptamine 1B (5-HT1B) receptor, an important mediator in the central nervous system that maintains a dynamic balance of the neurotransmitters, correlates with depression-like behavior. Serotonin 113-119 S100 calcium binding protein A10 Homo sapiens 43-50 31739800-0 2019 S100A10 silencing suppresses proliferation, migration and invasion of ovarian cancer cells and enhances sensitivity to carboplatin. Carboplatin 119-130 S100 calcium binding protein A10 Homo sapiens 0-7 31826542-4 2019 Results: The results of microarray analysis showed that LINC00052 was up-regulated by 1.32-fold, down-regulated by 1.64-fold and down-regulated by 4.92-fold in the malignant transformation early (P10) , middle term (P20) and late (P30) , respectively, The results of qPCR showed that compared with the DMSO control group, the expression of LINC00052 was up-regulated by 1.55 times, down-regulated by 1.20 times and down-regulated by 2.35 times in P10, P20 and P30, respectively, and the difference was statistically significant (P<0.05) . Dimethyl Sulfoxide 302-306 S100 calcium binding protein A10 Homo sapiens 196-199 31826542-5 2019 There was a statistically significant difference in the relative expression of NTRK3 between the GMA transformation group of P10 and P30 generations with the corresponding DMSO control group (P<0.05) . glycidyl methacrylate 97-100 S100 calcium binding protein A10 Homo sapiens 125-128 31739800-4 2019 The aims of the present study were to investigate the functional role of S100A10 in the progression and carboplatin sensitivity of ovarian cancer. Carboplatin 104-115 S100 calcium binding protein A10 Homo sapiens 73-80 31739800-8 2019 A xenograft tumor model was established to confirm the role of S100A10 in carboplatin resistance in vivo. Carboplatin 74-85 S100 calcium binding protein A10 Homo sapiens 63-70 31739800-10 2019 RESULTS: The results showed that increased expression of S100A10 was positively associated with carboplatin resistance (P < 0.001), tumor grade (P = 0.048) and a poorer prognosis (P = 0.0053). Carboplatin 96-107 S100 calcium binding protein A10 Homo sapiens 57-64 31739800-11 2019 Functional analyses demonstrated that S100A10 suppression significantly suppressed ovarian cancer cell proliferation, colony formation, cell migration and invasion, remarkably increased carboplatin-induced apoptosis in SKOV3 and A2780 cells and inhibited tumor growth in vivo. Carboplatin 186-197 S100 calcium binding protein A10 Homo sapiens 38-45 31739800-12 2019 Downregulation of S100A10 expression could inhibit cell proliferation and enhance ovarian cancer cell sensitivity to carboplatin, possibly involving the regulation of cleaved-Caspase3 and cleaved-PARP. Carboplatin 117-128 S100 calcium binding protein A10 Homo sapiens 18-25 31739800-13 2019 CONCLUSIONS: Together, the results of the present study reveal that S100A10 expression can be used as a predictive marker for the prognosis of ovarian cancer and chemosensitivity to carboplatin. Carboplatin 182-193 S100 calcium binding protein A10 Homo sapiens 68-75 31510525-3 2019 Optical pumping to the 2p9 level, followed by collisional relaxation to 2p10, is then used to produce lasing on the 2p10-1s5 transition. lasing 102-108 S100 calcium binding protein A10 Homo sapiens 73-76 31554266-4 2019 Notably, ketamine increased the proliferation of NPCs independent of the NMDA receptor, while transcriptome analysis revealed significant upregulation of insulin-like growth factor 2 (IGF2) and p11, a member of the S100 EF-hand protein family, which are both implicated in the pathophysiology of depression, 24 h after ketamine treatment. Ketamine 319-327 S100 calcium binding protein A10 Homo sapiens 194-197 31302140-6 2019 Dulaglutide suppressed high glucose- induced activation of NLRP3 inflammasome by reducing the expression of NLRP3, ASC, and cleaved caspase 1 (P10). Glucose 28-35 S100 calcium binding protein A10 Homo sapiens 143-146 31356860-0 2019 Eradication of meticillin-resistant Staphylococcus aureus from human skin by the novel LL-37-derived peptide P10 in four pharmaceutical ointments. Methicillin 15-25 S100 calcium binding protein A10 Homo sapiens 109-112 30884242-5 2019 The association of putative annexin A2-S100A10 partner candidates obtained by MS after column affinity was validated by immunofluorescence and sucrose density gradient separation. Sucrose 143-150 S100 calcium binding protein A10 Homo sapiens 39-46 31258789-9 2019 Based on the significant glycomics profile, a glyco-model composed of five glycan peaks (GP6, GP9, GP11, GP21 and GP23) was established with area under the receiver operating characteristic curve (AUC) value of 0.80 (training cohort) and 0.77 (validation cohort), which showed good potential in discriminating peritoneal metastasis from advanced gastric cancer. Polysaccharides 75-81 S100 calcium binding protein A10 Homo sapiens 99-103 30660990-7 2019 Importantly, anagliptin treatment downregulated high glucose- induced NLRP3 inflammasome activation, as evidenced by reducing the expressions of NLRP3, ASC, and cleaved caspase-1 (P10). anagliptin 13-23 S100 calcium binding protein A10 Homo sapiens 180-183 30557720-5 2019 The phenolic substances (P1P5), epoxides (P11 and P15), dialdehyde (P13) and other species (P8, P9, P10 and P14) are generated by OH additions and their subsequent reactions while OH abstraction reactions produce DCBP, P7 and chlorphenyl radical. Epoxy Compounds 32-40 S100 calcium binding protein A10 Homo sapiens 42-45 30677931-6 2019 In particular, after 7 days of P10 application, the highest As concentration in S6, S8 and TR soil solutions reached 2298.4, 829.9 and 153.9 mug/L respectively, with the AsV state accounting for 93%, 97% and 18% of As. Arsenic 60-62 S100 calcium binding protein A10 Homo sapiens 31-34 30677931-6 2019 In particular, after 7 days of P10 application, the highest As concentration in S6, S8 and TR soil solutions reached 2298.4, 829.9 and 153.9 mug/L respectively, with the AsV state accounting for 93%, 97% and 18% of As. asunaprevir 170-173 S100 calcium binding protein A10 Homo sapiens 31-34 30677931-6 2019 In particular, after 7 days of P10 application, the highest As concentration in S6, S8 and TR soil solutions reached 2298.4, 829.9 and 153.9 mug/L respectively, with the AsV state accounting for 93%, 97% and 18% of As. Arsenic 170-172 S100 calcium binding protein A10 Homo sapiens 31-34 30557720-5 2019 The phenolic substances (P1P5), epoxides (P11 and P15), dialdehyde (P13) and other species (P8, P9, P10 and P14) are generated by OH additions and their subsequent reactions while OH abstraction reactions produce DCBP, P7 and chlorphenyl radical. bis(2,4-dichlorobenzoyl)peroxide 213-217 S100 calcium binding protein A10 Homo sapiens 42-45 30557720-5 2019 The phenolic substances (P1P5), epoxides (P11 and P15), dialdehyde (P13) and other species (P8, P9, P10 and P14) are generated by OH additions and their subsequent reactions while OH abstraction reactions produce DCBP, P7 and chlorphenyl radical. chlorphenyl radical 226-245 S100 calcium binding protein A10 Homo sapiens 42-45 30660990-7 2019 Importantly, anagliptin treatment downregulated high glucose- induced NLRP3 inflammasome activation, as evidenced by reducing the expressions of NLRP3, ASC, and cleaved caspase-1 (P10). Glucose 53-60 S100 calcium binding protein A10 Homo sapiens 180-183 30617637-2 2019 For the effective transfection of p11 gene intracellularly, two cationic lipids based on phospholipid DOPE conjugated to basic amino acids histidine and arginine were synthesised, used for liposome formulation and evaluated for their ability as gene delivery vectors. Phospholipids 89-101 S100 calcium binding protein A10 Homo sapiens 34-37 30320415-5 2019 The correlation analysis analyzed the correlations of CD62P and P10 markers with serum creatinine (Scr), blood urea nitrogen (BUN), and subjective score; and logistic regression analysis was performed to reveal factors affecting the efficacy of HD. Creatinine 87-97 S100 calcium binding protein A10 Homo sapiens 64-67 30621740-3 2019 The aim of this study was to investigate the potential utility of all-trans retinoid acid (ATRA), an inhibitor of the annexin A2-S100A10 signalling pathway, as a new therapeutic against serous ovarian cancer. retinoid acid 76-89 S100 calcium binding protein A10 Homo sapiens 129-136 30621740-3 2019 The aim of this study was to investigate the potential utility of all-trans retinoid acid (ATRA), an inhibitor of the annexin A2-S100A10 signalling pathway, as a new therapeutic against serous ovarian cancer. Tretinoin 91-95 S100 calcium binding protein A10 Homo sapiens 129-136 30621740-4 2019 METHODS: In this study we determined the effects of ATRA treatment (1-5 muM) on annexin A2 and S100A10 expression, plasmin activation, and the ability of ATRA to inhibit serous ovarian cancer cell survival, motility and invasion in vitro. Tretinoin 52-56 S100 calcium binding protein A10 Homo sapiens 95-102 30621740-10 2019 In OAW28 cells, reduced cell survival following ATRA treatment was associated with a reduction of S100A10 mRNA and protein levels, S100A10 and annexin A2 membrane localization, plasmin generation, motility and invasion. Tretinoin 48-52 S100 calcium binding protein A10 Homo sapiens 98-105 30621740-10 2019 In OAW28 cells, reduced cell survival following ATRA treatment was associated with a reduction of S100A10 mRNA and protein levels, S100A10 and annexin A2 membrane localization, plasmin generation, motility and invasion. Tretinoin 48-52 S100 calcium binding protein A10 Homo sapiens 131-138 30621740-12 2019 CONCLUSIONS: These findings suggest that ATRA inhibits serous ovarian cancer proliferation and invasion via both S100A10 dependant and S100A10 independent mechanisms. Tretinoin 41-45 S100 calcium binding protein A10 Homo sapiens 113-120 30621740-12 2019 CONCLUSIONS: These findings suggest that ATRA inhibits serous ovarian cancer proliferation and invasion via both S100A10 dependant and S100A10 independent mechanisms. Tretinoin 41-45 S100 calcium binding protein A10 Homo sapiens 135-142 30617637-2 2019 For the effective transfection of p11 gene intracellularly, two cationic lipids based on phospholipid DOPE conjugated to basic amino acids histidine and arginine were synthesised, used for liposome formulation and evaluated for their ability as gene delivery vectors. Amino Acids, Basic 121-138 S100 calcium binding protein A10 Homo sapiens 34-37 30617637-2 2019 For the effective transfection of p11 gene intracellularly, two cationic lipids based on phospholipid DOPE conjugated to basic amino acids histidine and arginine were synthesised, used for liposome formulation and evaluated for their ability as gene delivery vectors. Histidine 139-148 S100 calcium binding protein A10 Homo sapiens 34-37 30617637-2 2019 For the effective transfection of p11 gene intracellularly, two cationic lipids based on phospholipid DOPE conjugated to basic amino acids histidine and arginine were synthesised, used for liposome formulation and evaluated for their ability as gene delivery vectors. Arginine 153-161 S100 calcium binding protein A10 Homo sapiens 34-37 30569205-2 2018 P10 was synthesized by solid-state synthesis and doxorubicin (DOX) was loaded via dialysis. Doxorubicin 49-60 S100 calcium binding protein A10 Homo sapiens 0-3 30580332-7 2019 BPA increased several cytokines in the medial prefrontal cortex (mPFC) of P10 males but not females. bisphenol A 0-3 S100 calcium binding protein A10 Homo sapiens 74-77 30580332-9 2019 BPA resulted in an increase in the gene expression of Esr1 in the mPFC of females on both P10 and P90. bisphenol A 0-3 S100 calcium binding protein A10 Homo sapiens 90-93 30394687-5 2019 Here, we demonstrated that S100A10 was succinylated at lysine residue 47 (K47), and levels of succinylated S100A10 were increased in human GC. Lysine 55-61 S100 calcium binding protein A10 Homo sapiens 27-34 30365935-7 2019 Nine N-glycan peaks (GPs (GP1, GP4, GP7, GP11, GP17, GP19, GP22, GP26, GP29)) were found to predict case status based on Akaike"s information criterion (AIC) and Bayesian information criterion (BIC) model selection. n-glycan 5-13 S100 calcium binding protein A10 Homo sapiens 41-45 30569205-2 2018 P10 was synthesized by solid-state synthesis and doxorubicin (DOX) was loaded via dialysis. Doxorubicin 62-65 S100 calcium binding protein A10 Homo sapiens 0-3 30206209-0 2018 Regulation of cell surface protease receptor S100A10 by retinoic acid therapy in acute promyelocytic leukemia (APL) . Tretinoin 56-69 S100 calcium binding protein A10 Homo sapiens 45-52 30206209-7 2018 ATRA treatment of MCF-7 breast cancer cells reduced p11 but not p36 transcript and protein levels, thus indicating that ATRA can regulate p11 levels independently of PML/RARalpha and p36. Tretinoin 0-4 S100 calcium binding protein A10 Homo sapiens 52-55 30206209-7 2018 ATRA treatment of MCF-7 breast cancer cells reduced p11 but not p36 transcript and protein levels, thus indicating that ATRA can regulate p11 levels independently of PML/RARalpha and p36. Tretinoin 0-4 S100 calcium binding protein A10 Homo sapiens 138-141 30218783-9 2018 We initiated GSK247246 treatment (i.p at 7 mg/kg or 20 mg/kg) after neuroinflammation was well established (on P6) and it was administered twice daily through to P10. gsk247246 13-22 S100 calcium binding protein A10 Homo sapiens 162-165 30206209-4 2018 Furthermore, treatment of the APL cell line, NB4 with all-trans retinoic acid (ATRA) causes the rapid loss of p36 and p11 protein. Tretinoin 54-77 S100 calcium binding protein A10 Homo sapiens 118-121 30206209-7 2018 ATRA treatment of MCF-7 breast cancer cells reduced p11 but not p36 transcript and protein levels, thus indicating that ATRA can regulate p11 levels independently of PML/RARalpha and p36. Tretinoin 120-124 S100 calcium binding protein A10 Homo sapiens 138-141 30206209-9 2018 The forced expression of ubiquitin and p11 in 293 T cells resulted in ubiquitylation of p11 that was blocked by mutagenesis of lysine 57. Lysine 127-133 S100 calcium binding protein A10 Homo sapiens 39-42 30206209-9 2018 The forced expression of ubiquitin and p11 in 293 T cells resulted in ubiquitylation of p11 that was blocked by mutagenesis of lysine 57. Lysine 127-133 S100 calcium binding protein A10 Homo sapiens 88-91 30206209-4 2018 Furthermore, treatment of the APL cell line, NB4 with all-trans retinoic acid (ATRA) causes the rapid loss of p36 and p11 protein. Tretinoin 79-83 S100 calcium binding protein A10 Homo sapiens 118-121 30206209-10 2018 This study highlights the complex regulation of p11 by retinoid signaling and challenges the hypothesis that ubiquitin-mediated proteasomal degradation of p11 represents a universal mechanism of regulation of this protein. Retinoids 55-63 S100 calcium binding protein A10 Homo sapiens 48-51 30206209-6 2018 Here, we show that the proteasomal inhibitor, lactacystin reversed the ATRA-dependent loss of p11, but did not cause an accumulation of ubiquitylated forms of p11, suggesting that ATRA promotes the proteasomal degradation of p11 in an ubiquitin-independent manner. lactacystin 46-57 S100 calcium binding protein A10 Homo sapiens 94-97 30206209-6 2018 Here, we show that the proteasomal inhibitor, lactacystin reversed the ATRA-dependent loss of p11, but did not cause an accumulation of ubiquitylated forms of p11, suggesting that ATRA promotes the proteasomal degradation of p11 in an ubiquitin-independent manner. Tretinoin 71-75 S100 calcium binding protein A10 Homo sapiens 94-97 28687976-8 2017 Treatment of zinc-induced U937/PR9 or circulating APL blasts with all-trans retinoic acid (ATRA) significantly reduced cell surface ANXA2 and S100A10 and associated reductions in IRPG and invasiveness. Tretinoin 66-89 S100 calcium binding protein A10 Homo sapiens 142-149 29111178-5 2018 The dose-dependent virotoxin effects observed across development following P10 Tat1-86 exposure were specific to spatial learning and absent from prepulse inhibition and locomotor activity. virotoxins 19-28 S100 calcium binding protein A10 Homo sapiens 75-78 29324674-8 2018 We found that calcitriol treatment in both right-sided and left-sided colon cancer causes a downregulation of ribosomal protein L37 and protein S100A10. Calcitriol 14-24 S100 calcium binding protein A10 Homo sapiens 144-151 29185755-5 2018 Bioinformatics data analysis and functional classification of proteins revealed a role of progesterone in calcium signaling in MCF-7 cells, and the major differentially expressed calcium regulators were S100A11, S100A10, calreticulin, VDAC1, SERCA3, and SERCA1. Calcium 179-186 S100 calcium binding protein A10 Homo sapiens 212-219 29172427-1 2017 This study investigates the hydrothermal stability of triamine-grafted CO2 adsorbent based on a commercial-grade silica (CARiACT, P10). triamine 54-62 S100 calcium binding protein A10 Homo sapiens 130-133 29172427-1 2017 This study investigates the hydrothermal stability of triamine-grafted CO2 adsorbent based on a commercial-grade silica (CARiACT, P10). N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide 71-74 S100 calcium binding protein A10 Homo sapiens 130-133 29172427-1 2017 This study investigates the hydrothermal stability of triamine-grafted CO2 adsorbent based on a commercial-grade silica (CARiACT, P10). Silicon Dioxide 113-119 S100 calcium binding protein A10 Homo sapiens 130-133 29172427-7 2017 Nevertheless, the large average pore width (21 nm) of the P10 silica led to higher hydrothermal stability of the amine-grafted sorbent compared to those with ordered pore structure supports, such as SBA-15 silica. Silicon Dioxide 62-68 S100 calcium binding protein A10 Homo sapiens 58-61 29172427-7 2017 Nevertheless, the large average pore width (21 nm) of the P10 silica led to higher hydrothermal stability of the amine-grafted sorbent compared to those with ordered pore structure supports, such as SBA-15 silica. Amines 113-118 S100 calcium binding protein A10 Homo sapiens 58-61 29172427-7 2017 Nevertheless, the large average pore width (21 nm) of the P10 silica led to higher hydrothermal stability of the amine-grafted sorbent compared to those with ordered pore structure supports, such as SBA-15 silica. sba-15 silica 199-212 S100 calcium binding protein A10 Homo sapiens 58-61 29947341-4 2018 METHODS: In this study, N9 microglial cells were treated with hemin, and subsequently used to detect the production of caspase-1 p10 and NLRP3 inflammasome assembly. Hemin 62-67 S100 calcium binding protein A10 Homo sapiens 129-132 29747344-15 2018 Age, sex, smoking status, education attainment and alcohol drinking were associated with P10 000 and PCW (P<0.05 for all). Alcohols 51-58 S100 calcium binding protein A10 Homo sapiens 89-92 28870124-7 2017 Similarly, the expression of NLRP3 and caspase-1 p10 and the release of IL-1beta and IL-18 were significantly increased after ZnO-NPs treatment, which indicated that the NLRP3 inflammasome was activated by ZnO-NPs. Zinc Oxide 126-129 S100 calcium binding protein A10 Homo sapiens 49-52 28870124-7 2017 Similarly, the expression of NLRP3 and caspase-1 p10 and the release of IL-1beta and IL-18 were significantly increased after ZnO-NPs treatment, which indicated that the NLRP3 inflammasome was activated by ZnO-NPs. Zinc Oxide 206-209 S100 calcium binding protein A10 Homo sapiens 49-52 28687976-8 2017 Treatment of zinc-induced U937/PR9 or circulating APL blasts with all-trans retinoic acid (ATRA) significantly reduced cell surface ANXA2 and S100A10 and associated reductions in IRPG and invasiveness. Tretinoin 91-95 S100 calcium binding protein A10 Homo sapiens 142-149 28382372-7 2017 S100A10 retains activity after substitution or deletion of the carboxyl-terminal lysine suggesting that internal lysine residues contribute to its plasmin generating activity. Lysine 81-87 S100 calcium binding protein A10 Homo sapiens 0-7 28631466-1 2017 Conjugated polymers with three components, P1-1 and P1-2, were prepared by one-pot Stille polymerization. Polymers 11-19 S100 calcium binding protein A10 Homo sapiens 43-56 28631466-2 2017 The two-component polymer P1-0 is only composed of a 5-fluoro-6-alkyloxybenzothiadiazole (AFBT) acceptor unit and a thiophene donor unit, while the three-component polymers P1-1 and P1-2 contain 10% and 20% 5,6-difluorobenzothiadiazole (DFBT), respectively, as the third component. afbt 90-94 S100 calcium binding protein A10 Homo sapiens 26-30 28631466-2 2017 The two-component polymer P1-0 is only composed of a 5-fluoro-6-alkyloxybenzothiadiazole (AFBT) acceptor unit and a thiophene donor unit, while the three-component polymers P1-1 and P1-2 contain 10% and 20% 5,6-difluorobenzothiadiazole (DFBT), respectively, as the third component. Thiophenes 116-125 S100 calcium binding protein A10 Homo sapiens 26-30 28631466-2 2017 The two-component polymer P1-0 is only composed of a 5-fluoro-6-alkyloxybenzothiadiazole (AFBT) acceptor unit and a thiophene donor unit, while the three-component polymers P1-1 and P1-2 contain 10% and 20% 5,6-difluorobenzothiadiazole (DFBT), respectively, as the third component. Polymers 164-172 S100 calcium binding protein A10 Homo sapiens 173-186 28631466-6 2017 The PCE of P1-1/PC71BM-based device was further enhanced to 8.79% after the use of 1,8-diiodooctane (DIO) as the solvent additive. 1,8-Diiodooctane 83-99 S100 calcium binding protein A10 Homo sapiens 11-15 28631466-6 2017 The PCE of P1-1/PC71BM-based device was further enhanced to 8.79% after the use of 1,8-diiodooctane (DIO) as the solvent additive. 3,3'-Dioctadecyloxacarbocyanine perchlorate 101-104 S100 calcium binding protein A10 Homo sapiens 11-15 28631466-7 2017 Most importantly, after the incorporation of 10% 5,6-difluorobenzothiadiazole unit, P1-1 exhibited a marked tolerance to the blend film thickness. 5,6-difluorobenzothiadiazole 49-77 S100 calcium binding protein A10 Homo sapiens 84-88 30970988-10 2017 Of the five polymers tested, P10 and P15 appeared to be promising drug delivery vehicles for poorly soluble drugs, due to the hydrophobic nature of the polymers. Polymers 12-20 S100 calcium binding protein A10 Homo sapiens 29-32 30970988-10 2017 Of the five polymers tested, P10 and P15 appeared to be promising drug delivery vehicles for poorly soluble drugs, due to the hydrophobic nature of the polymers. Polymers 152-160 S100 calcium binding protein A10 Homo sapiens 29-32 28424279-6 2017 Analysis of P10 mutants encoded by recombinant baculoviruses in which putative phosphorylation residues were mutated to alanine showed that serine 93 is a site of phosphorylation. Alanine 120-127 S100 calcium binding protein A10 Homo sapiens 12-15 28424279-6 2017 Analysis of P10 mutants encoded by recombinant baculoviruses in which putative phosphorylation residues were mutated to alanine showed that serine 93 is a site of phosphorylation. Serine 140-146 S100 calcium binding protein A10 Homo sapiens 12-15 28424279-9 2017 Together, these data suggest that the phosphorylation of serine 93 affects the structural conformation of P10.IMPORTANCE The baculovirus P10 protein has been researched intensively since it was first observed in 1969, but its role during viral infection remains unclear. Serine 57-63 S100 calcium binding protein A10 Homo sapiens 106-109 28424279-9 2017 Together, these data suggest that the phosphorylation of serine 93 affects the structural conformation of P10.IMPORTANCE The baculovirus P10 protein has been researched intensively since it was first observed in 1969, but its role during viral infection remains unclear. Serine 57-63 S100 calcium binding protein A10 Homo sapiens 137-140 28382372-7 2017 S100A10 retains activity after substitution or deletion of the carboxyl-terminal lysine suggesting that internal lysine residues contribute to its plasmin generating activity. Lysine 113-119 S100 calcium binding protein A10 Homo sapiens 0-7 25450808-0 2015 The p10 FAST protein fusion peptide functions as a cystine noose to induce cholesterol-dependent liposome fusion without liposome tubulation. cystine noose 51-64 S100 calcium binding protein A10 Homo sapiens 4-7 27914067-12 2017 Thus, MDS with der(5;19)(p10;q10) may represent a platinum agent-related t-MDS that is highly resistant to chemotherapy. Platinum 50-58 S100 calcium binding protein A10 Homo sapiens 25-28 27895642-4 2016 The citrulline residues in the eight identified peptides are distributed throughout the entire length of the presented epitopes and more specifically, localized at peptide positions p-2, p2, p4, p6, p7, p10, and p11. Citrulline 4-14 S100 calcium binding protein A10 Homo sapiens 203-206 27895642-4 2016 The citrulline residues in the eight identified peptides are distributed throughout the entire length of the presented epitopes and more specifically, localized at peptide positions p-2, p2, p4, p6, p7, p10, and p11. Citrulline 4-14 S100 calcium binding protein A10 Homo sapiens 212-215 27287014-4 2016 The treatment with hydroxytyrosol extract significantly (P < 0.001) increased apoptosis in P10 and P20 cells in comparison to control and A7 cells; significantly (P < 0.001) reduced triglyceride accumulation in P20 cells compared to P10 and control cells; and significantly (P < 0.001) increased lipolysis in P20 cells in comparison to control cells and A7 mature adipocytes. 3,4-dihydroxyphenylethanol 19-33 S100 calcium binding protein A10 Homo sapiens 94-97 27287014-4 2016 The treatment with hydroxytyrosol extract significantly (P < 0.001) increased apoptosis in P10 and P20 cells in comparison to control and A7 cells; significantly (P < 0.001) reduced triglyceride accumulation in P20 cells compared to P10 and control cells; and significantly (P < 0.001) increased lipolysis in P20 cells in comparison to control cells and A7 mature adipocytes. 3,4-dihydroxyphenylethanol 19-33 S100 calcium binding protein A10 Homo sapiens 239-242 26925708-8 2016 Moreover, high cytoplasmic S100A10 staining was significantly associated with reduced OS (P = 0.027). Osmium 86-88 S100 calcium binding protein A10 Homo sapiens 27-34 26428141-3 2015 The results revealed that GP11 was composed of 1)-D-Manp-(6 , 1)-D-Glcp-(4 , 1)-D-Galp-(6 and 2,3,6)-D-Glcp-(1 , with branches attached at O-2,3 of 1,2,3,6-linked Glcp residues and terminal T-Glcp. 1)-d-manp 49-58 S100 calcium binding protein A10 Homo sapiens 26-30 26428141-3 2015 The results revealed that GP11 was composed of 1)-D-Manp-(6 , 1)-D-Glcp-(4 , 1)-D-Galp-(6 and 2,3,6)-D-Glcp-(1 , with branches attached at O-2,3 of 1,2,3,6-linked Glcp residues and terminal T-Glcp. (6 , 1)-d-glcp 59-75 S100 calcium binding protein A10 Homo sapiens 26-30 26428141-3 2015 The results revealed that GP11 was composed of 1)-D-Manp-(6 , 1)-D-Glcp-(4 , 1)-D-Galp-(6 and 2,3,6)-D-Glcp-(1 , with branches attached at O-2,3 of 1,2,3,6-linked Glcp residues and terminal T-Glcp. (4 , 1)-d-galp 76-92 S100 calcium binding protein A10 Homo sapiens 26-30 26428141-3 2015 The results revealed that GP11 was composed of 1)-D-Manp-(6 , 1)-D-Glcp-(4 , 1)-D-Galp-(6 and 2,3,6)-D-Glcp-(1 , with branches attached at O-2,3 of 1,2,3,6-linked Glcp residues and terminal T-Glcp. 6)-d-glcp 108-117 S100 calcium binding protein A10 Homo sapiens 26-30 26428141-3 2015 The results revealed that GP11 was composed of 1)-D-Manp-(6 , 1)-D-Glcp-(4 , 1)-D-Galp-(6 and 2,3,6)-D-Glcp-(1 , with branches attached at O-2,3 of 1,2,3,6-linked Glcp residues and terminal T-Glcp. glcp 71-75 S100 calcium binding protein A10 Homo sapiens 26-30 26428141-6 2015 GP11 stimulated tumoricidal activity and the production of nitric oxide (NO), TNF-alpha and interleukin-1beta, and it also stimulated the protein expression of iNOS and mRNA expression of iNOS and TNF-alpha. Nitric Oxide 59-71 S100 calcium binding protein A10 Homo sapiens 0-4 28418321-12 2017 CONCLUSION: The S100A10 and S100B genes, which are located on different chromosomes, encode specialized calcium-binding proteins. Calcium 104-111 S100 calcium binding protein A10 Homo sapiens 16-23 27188390-7 2016 RESULTS: Propidium iodide staining showed that P10 in combination with SAHA induced cell death in Nalm6 cells, in which PARP expression and activity is high with a combination index of <0.2. Propidium 9-25 S100 calcium binding protein A10 Homo sapiens 47-50 27188390-8 2016 Annexin-FITC/PI staining, JC-1 staining, and other biochemical assays revealed that P10 in combination with SAHA induced apoptosis by causing a change in mitochondrial membrane potential in >65 % cells. annexin-fitc 0-12 S100 calcium binding protein A10 Homo sapiens 84-87 27188390-10 2016 Finally, we demonstrated that treatment with P10 led to DNA strand breaks, which were further potentiated by SAHA (p < 0.01), leading to activation of apoptosis and increased cell death in PARP-positive leukemic cells. Vorinostat 109-113 S100 calcium binding protein A10 Homo sapiens 45-48 27183920-7 2016 Both at low and high GSH concentrations, high activities of GSTA1-1, A2-2, A3-3, M1-1, M3-3 and P1-1 in the inactivation of these QIs were found. Glutathione 21-24 S100 calcium binding protein A10 Homo sapiens 96-100 27046018-7 2016 At elevated temperatures, 2,3-butadienal + H (P10) is also a major product. 1,2-Butadienal 26-40 S100 calcium binding protein A10 Homo sapiens 46-49 26329302-9 2016 In primary culture of porcine oviductal cells, the expression of ANXA2 is increased by progesterone, while the expression of S100A10 is increased by progesterone and estradiol. Progesterone 149-161 S100 calcium binding protein A10 Homo sapiens 125-132 26329302-9 2016 In primary culture of porcine oviductal cells, the expression of ANXA2 is increased by progesterone, while the expression of S100A10 is increased by progesterone and estradiol. Estradiol 166-175 S100 calcium binding protein A10 Homo sapiens 125-132 26639426-4 2016 Here, we found that acute (within 2min) bath-application of rapamycin (0.5mugml(-1)) was able to depolarize the current-clamp baseline potentials significantly at postnatal day (P) 4, P10 in rats and P90 in mice (P<0.05), and altered the membrane current/voltage (I/V) curves in an age-dependent manner. Sirolimus 60-69 S100 calcium binding protein A10 Homo sapiens 184-187 26639426-5 2016 Rapamycin not only increased the standard deviation or the peak amplitude of baseline membrane potential, but also increased the frequencies of spontaneous action potentials in more mature neurons (P10 and P90). Sirolimus 0-9 S100 calcium binding protein A10 Homo sapiens 198-201 26522247-1 2016 A polysaccharide termed Se-GP11 was extracted and purified from Se-enriched Grifola frondosa in our previous study. Polysaccharides 2-16 S100 calcium binding protein A10 Homo sapiens 27-31 26522247-3 2016 The results showed that Se-GP11 was composed of mannose, glucose and galactose with a molar ratio of 1:4.91:2.41. Mannose 48-55 S100 calcium binding protein A10 Homo sapiens 27-31 26522247-4 2016 The weight-average molecular weight (Mw) and weight-average mean square radius (Rw) of Se-GP11 in 0.1M sodium chloride solution were 3.3x10(4)Da and 32.8 nm. Sodium Chloride 103-118 S100 calcium binding protein A10 Homo sapiens 90-94 25450808-0 2015 The p10 FAST protein fusion peptide functions as a cystine noose to induce cholesterol-dependent liposome fusion without liposome tubulation. Cholesterol 75-86 S100 calcium binding protein A10 Homo sapiens 4-7 25450808-2 2015 The 36-40-residue ectodomains of avian reovirus (ARV) and Nelson Bay reovirus (NBV) p10 contain an essential intramolecular disulfide bond required for both cell-cell fusion and lipid mixing between liposomes. Disulfides 124-133 S100 calcium binding protein A10 Homo sapiens 84-87 25450808-6 2015 In addition, p10 fusion peptide activity, but not membrane partitioning, is dependent on membrane cholesterol. Cholesterol 98-109 S100 calcium binding protein A10 Homo sapiens 13-16 25142552-3 2015 The single-modification peptides (P-1-1, P-2-1 and P-3-1) and double-modification peptides (P-1-2, P-2-2 and P-3-2) showed significantly lower immunoglobulin (Ig)E binding with patients" sera compared to osmotin (P < 0 01). osmotin 204-211 S100 calcium binding protein A10 Homo sapiens 34-39 25324722-6 2014 This study characterized 8-methoxypsoralen (8-MOP) as a human GST P1-1 (hGST P1-1) inhibitor. Methoxsalen 25-42 S100 calcium binding protein A10 Homo sapiens 66-70 25428414-7 2015 Baseline S100A10 (p = 0.02) and TPH1 (p = 0.02) expression were significantly higher in the ramosetron responders than in the non-responders. ramosetron 92-102 S100 calcium binding protein A10 Homo sapiens 9-16 25428414-10 2015 CONCLUSIONS & INFERENCES: TPH1 gene polymorphisms and S100A10 expression, which correlate with 5-HT signaling were associated with ramosetron effectiveness in IBS-D, and may possibly lead to prospective identification of the resistance to treatment. ramosetron 135-145 S100 calcium binding protein A10 Homo sapiens 58-65 25393952-0 2014 Inactivation of human salivary glutathione transferase P1-1 by hypothiocyanite: a post-translational control system in search of a role. hypothiocyanite ion 63-78 S100 calcium binding protein A10 Homo sapiens 55-59 25324722-0 2014 8-Methoxypsoralen is a competitive inhibitor of glutathione S-transferase P1-1. Methoxsalen 0-17 S100 calcium binding protein A10 Homo sapiens 74-78 25324722-6 2014 This study characterized 8-methoxypsoralen (8-MOP) as a human GST P1-1 (hGST P1-1) inhibitor. Methoxsalen 44-49 S100 calcium binding protein A10 Homo sapiens 66-70 24851084-0 2014 Forced expression of S100A10 reduces sensitivity to oxaliplatin in colorectal cancer cells. Oxaliplatin 52-63 S100 calcium binding protein A10 Homo sapiens 21-28 24851084-2 2014 Our recent proteomics studies have demonstrated that intracellular protein expression levels of S100A10 are significantly correlated with the sensitivity of colorectal cancer (CRC) cells to L-OHP, but not 5-FU, suggesting that S100A10 is a candidate predictive marker for the response to L-OHP. Oxaliplatin 190-195 S100 calcium binding protein A10 Homo sapiens 96-103 24851084-2 2014 Our recent proteomics studies have demonstrated that intracellular protein expression levels of S100A10 are significantly correlated with the sensitivity of colorectal cancer (CRC) cells to L-OHP, but not 5-FU, suggesting that S100A10 is a candidate predictive marker for the response to L-OHP. Oxaliplatin 190-195 S100 calcium binding protein A10 Homo sapiens 227-234 24851084-2 2014 Our recent proteomics studies have demonstrated that intracellular protein expression levels of S100A10 are significantly correlated with the sensitivity of colorectal cancer (CRC) cells to L-OHP, but not 5-FU, suggesting that S100A10 is a candidate predictive marker for the response to L-OHP. Oxaliplatin 288-293 S100 calcium binding protein A10 Homo sapiens 96-103 24851084-2 2014 Our recent proteomics studies have demonstrated that intracellular protein expression levels of S100A10 are significantly correlated with the sensitivity of colorectal cancer (CRC) cells to L-OHP, but not 5-FU, suggesting that S100A10 is a candidate predictive marker for the response to L-OHP. Oxaliplatin 288-293 S100 calcium binding protein A10 Homo sapiens 227-234 24851084-3 2014 In this study, we investigated whether S100A10 is involved in L-OHP sensitivity or not. l 62-63 S100 calcium binding protein A10 Homo sapiens 39-46 24851084-3 2014 In this study, we investigated whether S100A10 is involved in L-OHP sensitivity or not. 2-hydroxyphenylacetic acid 64-67 S100 calcium binding protein A10 Homo sapiens 39-46 24851084-4 2014 RESULTS: Forced expression of S100A10 in COLO-320 CRC cells significantly increased the 50% inhibitory concentration (IC50) for L-OHP (P = 0.003), but did not change that for 5-FU, indicating that S100A10 is more specific to L-OHP than 5-FU. Oxaliplatin 128-133 S100 calcium binding protein A10 Homo sapiens 30-37 24851084-4 2014 RESULTS: Forced expression of S100A10 in COLO-320 CRC cells significantly increased the 50% inhibitory concentration (IC50) for L-OHP (P = 0.003), but did not change that for 5-FU, indicating that S100A10 is more specific to L-OHP than 5-FU. Oxaliplatin 225-230 S100 calcium binding protein A10 Homo sapiens 30-37 24851084-4 2014 RESULTS: Forced expression of S100A10 in COLO-320 CRC cells significantly increased the 50% inhibitory concentration (IC50) for L-OHP (P = 0.003), but did not change that for 5-FU, indicating that S100A10 is more specific to L-OHP than 5-FU. Fluorouracil 236-240 S100 calcium binding protein A10 Homo sapiens 30-37 24851084-8 2014 CONCLUSIONS: The present results have shown that protein expression of S100A10 was associated with resistance to L-OHP, but not 5-FU, supporting the hypothesis that S100A10 expression may predict L-OHP sensitivity. Oxaliplatin 113-118 S100 calcium binding protein A10 Homo sapiens 71-78 24851084-8 2014 CONCLUSIONS: The present results have shown that protein expression of S100A10 was associated with resistance to L-OHP, but not 5-FU, supporting the hypothesis that S100A10 expression may predict L-OHP sensitivity. Oxaliplatin 196-201 S100 calcium binding protein A10 Homo sapiens 71-78 24851084-8 2014 CONCLUSIONS: The present results have shown that protein expression of S100A10 was associated with resistance to L-OHP, but not 5-FU, supporting the hypothesis that S100A10 expression may predict L-OHP sensitivity. Oxaliplatin 196-201 S100 calcium binding protein A10 Homo sapiens 165-172 24851084-9 2014 Thus, our present study provides basic findings to support that S100A10 expression can be used as a predictive marker for tumor sensitivity to L-OHP. Oxaliplatin 143-148 S100 calcium binding protein A10 Homo sapiens 64-71 24591154-10 2014 Superoxide levels were increased in the presence of AZT/ddI and significantly decreased in cells exposed to AZT/3TC/Tempol at P3, P7, and P10. Superoxides 0-10 S100 calcium binding protein A10 Homo sapiens 138-141 24591154-10 2014 Superoxide levels were increased in the presence of AZT/ddI and significantly decreased in cells exposed to AZT/3TC/Tempol at P3, P7, and P10. azt/3tc/tempol 108-122 S100 calcium binding protein A10 Homo sapiens 138-141 24351841-4 2013 Four types of polymers were synthesised: P10, P11, P151, and P15. Polymers 14-22 S100 calcium binding protein A10 Homo sapiens 41-44 24351841-4 2013 Four types of polymers were synthesised: P10, P11, P151, and P15. Polymers 14-22 S100 calcium binding protein A10 Homo sapiens 46-49 23823806-3 2013 In this study we investigated the possibility that p10-mer, a decapeptide from durum wheat (QQPQDAVQPF), which was previously shown to prevent the activation of celiac peripheral lymphocytes, may exert an inhibitory effect on peptic-tryptic digested gliadin (PT-Gly)-stimulated intestinal carcinoma CACO-2 cells. pt-gly 259-265 S100 calcium binding protein A10 Homo sapiens 51-54 23757730-5 2013 Knockdown and specific rescue approaches reveal that a functional AnxA2-S100A10 complex is required for the forskolin-induced, cAMP-dependent release of VWF. Colforsin 108-117 S100 calcium binding protein A10 Homo sapiens 72-79 23757730-5 2013 Knockdown and specific rescue approaches reveal that a functional AnxA2-S100A10 complex is required for the forskolin-induced, cAMP-dependent release of VWF. Cyclic AMP 127-131 S100 calcium binding protein A10 Homo sapiens 72-79 23757730-6 2013 Forskolin triggers dephosphorylation of AnxA2 that is mediated by a calcineurin-like phosphatase and stabilizes the AnxA2-S100A10 complex, thereby promoting VWF release. Colforsin 0-9 S100 calcium binding protein A10 Homo sapiens 122-129 23757730-7 2013 Serine 11 of AnxA2 was identified as the target residue of this phosphorylation switch because a phosphomimicking mutation at this site prevents complex formation with S100A10 and, in contrast to wild-type or S11A-AnxA2, is unable to restore cAMP-dependent VWF secretion in AnxA2-depleted cells. Serine 0-6 S100 calcium binding protein A10 Homo sapiens 168-175 23757730-8 2013 Thus, complex formation of AnxA2 with S100A10 is a central regulatory mechanism in the acute release of VWF in response to cAMP-elevating agonists. Cyclic AMP 123-127 S100 calcium binding protein A10 Homo sapiens 38-45 23595519-8 2013 S100A10 expression in the rectal epithelium of the IBS patients was significantly higher (0.643 vs. 0.402, p = 0.01) than in controls and correlated with the SDS scores (r = 0.41, p = 0.002). Sodium Dodecyl Sulfate 158-161 S100 calcium binding protein A10 Homo sapiens 0-7 23887631-9 2013 Nine stemness-linked genes (ABCB1, ABCC4, LMO2, SOX2, ERCC5, S100A10, IGFBP3, TCF3, and VIM) were downregulated in vorinostat-treated doxorubicin-resistant SK-N-Be(2)C cells relative to doxorubicin-resistant cells. Vorinostat 115-125 S100 calcium binding protein A10 Homo sapiens 61-68 23874836-6 2013 In addition, upon oxaliplatin treatment of Pokemon-silenced cells, the FAS receptor, FADD and their downstream targets caspase-10 and caspase-8 were activated, causing increased release of caspase-8 active fragments p18 and p10. Oxaliplatin 18-29 S100 calcium binding protein A10 Homo sapiens 224-227 23696646-0 2013 Ceramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complex. ceramide 1-phosphate 0-20 S100 calcium binding protein A10 Homo sapiens 75-78 23696646-3 2013 We have now identified and characterized interactions between ceramide 1-phosphate and the annexin a2-p11 heterotetramer constituents. ceramide 1-phosphate 62-82 S100 calcium binding protein A10 Homo sapiens 102-105 23823806-5 2013 Our results showed that pre-treatment of CACO-2 cells with p10-mer significantly inhibited IRAK1 activation and NF-kB, ERK1/2 and p38 MAPK phosphorylation, as well as COX-2 activity (i.e. PGE-2 release) and production of the IL-6 and IL-8 pro-inflammatory cytokines, induced by gliadin peptides. Prostaglandins E 188-191 S100 calcium binding protein A10 Homo sapiens 59-62 23334362-6 2013 shRNA-mediated knockdown of either ANXA2, FYN, LCK or S100A10, all led to inhibition of annexin A2 phosphorylation and resulted in marked sensitization to prednisolone. Prednisolone 155-167 S100 calcium binding protein A10 Homo sapiens 54-61 23527582-5 2013 Neomycin B, an aminoglycoside antibiotic, which strongly inhibited the catalytic properties of delta ribozyme, was bound to the pocket formed by the P1 stem, the P1.1 pseudoknot, and the J4/2 junction. Framycetin 0-10 S100 calcium binding protein A10 Homo sapiens 162-166 23527582-5 2013 Neomycin B, an aminoglycoside antibiotic, which strongly inhibited the catalytic properties of delta ribozyme, was bound to the pocket formed by the P1 stem, the P1.1 pseudoknot, and the J4/2 junction. Aminoglycosides 15-29 S100 calcium binding protein A10 Homo sapiens 162-166 23275167-8 2013 Additionally, the various hydrogen bonds formed between the AHNAK peptide and (p11)(2)(AnxA2)(2) most often involve backbone atoms of AHNAK; as a result, the side chains, particularly those that point away from S100A10/AnxA2 towards the solvent, are largely interchangeable. Hydrogen 26-34 S100 calcium binding protein A10 Homo sapiens 79-82 23415230-6 2013 The SSRI fluoxetine induces expression of p11 in both cell types and increases the amount of the ternary complex of p11/annexin A2/SMARCA3. Fluoxetine 9-19 S100 calcium binding protein A10 Homo sapiens 42-45 23415230-6 2013 The SSRI fluoxetine induces expression of p11 in both cell types and increases the amount of the ternary complex of p11/annexin A2/SMARCA3. Fluoxetine 9-19 S100 calcium binding protein A10 Homo sapiens 116-119 23275167-8 2013 Additionally, the various hydrogen bonds formed between the AHNAK peptide and (p11)(2)(AnxA2)(2) most often involve backbone atoms of AHNAK; as a result, the side chains, particularly those that point away from S100A10/AnxA2 towards the solvent, are largely interchangeable. Hydrogen 26-34 S100 calcium binding protein A10 Homo sapiens 211-218 23151508-4 2012 p10" also prevented the death of neurons treated with the neurotoxin, 1-methyl-4-phenylpyridinium (MPP(+)), which induces conversion of endogenous p35 to p25, and Parkinson disease (PD)-like symptoms in animals. 1-Methyl-4-phenylpyridinium 70-97 S100 calcium binding protein A10 Homo sapiens 0-3 23151508-4 2012 p10" also prevented the death of neurons treated with the neurotoxin, 1-methyl-4-phenylpyridinium (MPP(+)), which induces conversion of endogenous p35 to p25, and Parkinson disease (PD)-like symptoms in animals. mangion-purified polysaccharide (Candida albicans) 99-102 S100 calcium binding protein A10 Homo sapiens 0-3 23151508-6 2012 We found that p10" expression inhibited both Prx2 phosphorylation and ROS accumulation in neurons. Reactive Oxygen Species 70-73 S100 calcium binding protein A10 Homo sapiens 14-17 22609128-2 2012 The active gas is mixed with argon-methane (P-10) and passed to the counters. argon-methane 29-42 S100 calcium binding protein A10 Homo sapiens 44-48 22940583-5 2012 The structure evokes a model whereby AHNAK is targeted to the membrane surface through sandwiching of the binding region between the S100A10/annexin A2 complex and the phospholipid membrane. Phospholipids 168-180 S100 calcium binding protein A10 Homo sapiens 133-140 22998212-0 2012 Mass spectrometric characterization of protein adducts of multiple P450-dependent reactive intermediates of diclofenac to human glutathione-S-transferase P1-1. Diclofenac 108-118 S100 calcium binding protein A10 Homo sapiens 154-158 22998212-4 2012 DF and its major monohydroxylated metabolites 4"-hydroxydiclofenac (4"-OH-DF) and 5-hydroxydiclofenac (5-OH-DF) were bioactivated using a highly active P450 BM3 mutant (CYP102A1M11H) in the presence of the model target protein human glutathione-S-transferase P1-1 (hGST P1-1). 4'-hydroxydiclofenac 46-66 S100 calcium binding protein A10 Homo sapiens 259-263 22998212-4 2012 DF and its major monohydroxylated metabolites 4"-hydroxydiclofenac (4"-OH-DF) and 5-hydroxydiclofenac (5-OH-DF) were bioactivated using a highly active P450 BM3 mutant (CYP102A1M11H) in the presence of the model target protein human glutathione-S-transferase P1-1 (hGST P1-1). 4'-hydroxydiclofenac 46-66 S100 calcium binding protein A10 Homo sapiens 270-274 22998212-4 2012 DF and its major monohydroxylated metabolites 4"-hydroxydiclofenac (4"-OH-DF) and 5-hydroxydiclofenac (5-OH-DF) were bioactivated using a highly active P450 BM3 mutant (CYP102A1M11H) in the presence of the model target protein human glutathione-S-transferase P1-1 (hGST P1-1). 4"-oh-df 68-76 S100 calcium binding protein A10 Homo sapiens 259-263 22998212-4 2012 DF and its major monohydroxylated metabolites 4"-hydroxydiclofenac (4"-OH-DF) and 5-hydroxydiclofenac (5-OH-DF) were bioactivated using a highly active P450 BM3 mutant (CYP102A1M11H) in the presence of the model target protein human glutathione-S-transferase P1-1 (hGST P1-1). 4"-oh-df 68-76 S100 calcium binding protein A10 Homo sapiens 270-274 22998212-4 2012 DF and its major monohydroxylated metabolites 4"-hydroxydiclofenac (4"-OH-DF) and 5-hydroxydiclofenac (5-OH-DF) were bioactivated using a highly active P450 BM3 mutant (CYP102A1M11H) in the presence of the model target protein human glutathione-S-transferase P1-1 (hGST P1-1). 5-hydroxydiclofenac 82-101 S100 calcium binding protein A10 Homo sapiens 259-263 22998212-4 2012 DF and its major monohydroxylated metabolites 4"-hydroxydiclofenac (4"-OH-DF) and 5-hydroxydiclofenac (5-OH-DF) were bioactivated using a highly active P450 BM3 mutant (CYP102A1M11H) in the presence of the model target protein human glutathione-S-transferase P1-1 (hGST P1-1). 5-hydroxydiclofenac 82-101 S100 calcium binding protein A10 Homo sapiens 270-274 22998212-4 2012 DF and its major monohydroxylated metabolites 4"-hydroxydiclofenac (4"-OH-DF) and 5-hydroxydiclofenac (5-OH-DF) were bioactivated using a highly active P450 BM3 mutant (CYP102A1M11H) in the presence of the model target protein human glutathione-S-transferase P1-1 (hGST P1-1). 5-oh-df 103-110 S100 calcium binding protein A10 Homo sapiens 259-263 22998212-4 2012 DF and its major monohydroxylated metabolites 4"-hydroxydiclofenac (4"-OH-DF) and 5-hydroxydiclofenac (5-OH-DF) were bioactivated using a highly active P450 BM3 mutant (CYP102A1M11H) in the presence of the model target protein human glutathione-S-transferase P1-1 (hGST P1-1). 5-oh-df 103-110 S100 calcium binding protein A10 Homo sapiens 270-274 22797859-11 2012 Furthermore, the calcium concentration increase in HCs stimulated by LPS was also inhibited by S100A10 knockdown. Calcium 17-24 S100 calcium binding protein A10 Homo sapiens 95-102 22609128-5 2012 This paper describes the initial experimental studies performed to enable the extension of the MC model based loss correction method to gases other than carbon dioxide in P-10. Methylcholanthrene 95-97 S100 calcium binding protein A10 Homo sapiens 171-175 22533359-6 2012 The nonchlorine-based probabilistic emission factor model, which addresses the log-normal distribution of the mercury content of coal, estimates that the mercury emission from CFPPs is 96.5 t (P50), with a confidence interval of 57.3 t (P10) to 183.0 t (P90). nonchlorine 4-15 S100 calcium binding protein A10 Homo sapiens 237-240 22644793-0 2012 Three-dimensional pharmacophore design and biochemical screening identifies substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction. 1,2,4-triazole 88-103 S100 calcium binding protein A10 Homo sapiens 136-143 22740430-1 2012 Human glutathione S-transferase P1-1 (hGST P1-1) is involved in cell detoxification processes through the conjugation of its natural substrate, reduced glutathione (GSH), with xenobiotics. Glutathione 6-17 S100 calcium binding protein A10 Homo sapiens 32-36 22740430-1 2012 Human glutathione S-transferase P1-1 (hGST P1-1) is involved in cell detoxification processes through the conjugation of its natural substrate, reduced glutathione (GSH), with xenobiotics. Glutathione 6-17 S100 calcium binding protein A10 Homo sapiens 43-47 22740430-1 2012 Human glutathione S-transferase P1-1 (hGST P1-1) is involved in cell detoxification processes through the conjugation of its natural substrate, reduced glutathione (GSH), with xenobiotics. Glutathione 165-168 S100 calcium binding protein A10 Homo sapiens 32-36 22740430-1 2012 Human glutathione S-transferase P1-1 (hGST P1-1) is involved in cell detoxification processes through the conjugation of its natural substrate, reduced glutathione (GSH), with xenobiotics. Glutathione 165-168 S100 calcium binding protein A10 Homo sapiens 43-47 22533359-6 2012 The nonchlorine-based probabilistic emission factor model, which addresses the log-normal distribution of the mercury content of coal, estimates that the mercury emission from CFPPs is 96.5 t (P50), with a confidence interval of 57.3 t (P10) to 183.0 t (P90). Mercury 154-161 S100 calcium binding protein A10 Homo sapiens 237-240 21908427-6 2011 The ANXA2 subunit of AIIt functions to stabilize and anchor S100A10 to the plasma membrane, whereas the S100A10 subunit initiates the fibrinolytic cascade by colocalizing with the urokinase type plasminogen activator and receptor complex and also providing a common binding site for both tissue-type plasminogen activator and plasminogen via its C-terminal lysine residue. Lysine 357-363 S100 calcium binding protein A10 Homo sapiens 104-111 22934778-2 2012 Alkyl esters bearing chain lengths of 4 (P4), 7 (P7) and 10 (P10) carbons were synthesized and their oxidation potential, hydrophobicity, antiradical activity, inhibition of superoxide anion (O2 (-)), and the abilities to affect hypochlorous acid (HOCl) production by leukocytes and inhibit myeloperoxidase (MPO) chlorinating activity were studied. alkyl esters 0-12 S100 calcium binding protein A10 Homo sapiens 61-64 22934778-2 2012 Alkyl esters bearing chain lengths of 4 (P4), 7 (P7) and 10 (P10) carbons were synthesized and their oxidation potential, hydrophobicity, antiradical activity, inhibition of superoxide anion (O2 (-)), and the abilities to affect hypochlorous acid (HOCl) production by leukocytes and inhibit myeloperoxidase (MPO) chlorinating activity were studied. Carbon 66-73 S100 calcium binding protein A10 Homo sapiens 61-64 21682946-6 2012 The escitalopram-induced hypomethylation was associated with both an increase in P11 gene expression and a reduction in mRNA levels of two DNA methyltransferases that have been shown to maintain DNA methylation in adult forebrain neurons (Dnmt1 and Dnmt3a). Citalopram 4-16 S100 calcium binding protein A10 Homo sapiens 81-84 22206547-0 2011 S100A10 protein expression is associated with oxaliplatin sensitivity in human colorectal cancer cells. Oxaliplatin 46-57 S100 calcium binding protein A10 Homo sapiens 0-7 22206547-7 2011 We verified its differential expression and the correlation between S100A10 protein expression levels in drug-untreated CRC cells and their L-OHP sensitivities by Western blot analyses. Oxaliplatin 140-145 S100 calcium binding protein A10 Homo sapiens 68-75 22206547-8 2011 In addition, S100A10 protein expression levels were not correlated with sensitivity to 5-fluorouracil, suggesting that S100A10 is more specific to L-OHP than to 5-fluorouracil in CRC cells. Oxaliplatin 147-152 S100 calcium binding protein A10 Homo sapiens 119-126 22206547-10 2011 CONCLUSIONS: By proteomic approaches including SELDI technology, we have demonstrated that intracellular S100A10 protein expression levels in drug-untreated CRC cells differ according to cell lines and are significantly correlated with sensitivity of CRC cells to L-OHP exposure. Oxaliplatin 264-269 S100 calcium binding protein A10 Homo sapiens 105-112 20830735-3 2010 Here we report unprecedented detection of endogenous p10, the smaller proteolytic fragment of the Cdk5 activator p35 in treated primary cortical neurons that underwent significant apoptosis, triggered by proteasome inhibitors MG132 and lactacystin, and protein kinase inhibitor staurosporine (STS). benzyloxycarbonylleucyl-leucyl-leucine aldehyde 226-231 S100 calcium binding protein A10 Homo sapiens 53-56 21639118-5 2011 The applicability of our procedure is demonstrated by the trapping of RMs of acetaminophen (APAP), clozapine (CLOZ), and troglitazone (TGZ) with human glutathione-S-transferase P1-1 (hGST P1-1) as the model target protein. Clozapine 99-108 S100 calcium binding protein A10 Homo sapiens 177-181 21639118-5 2011 The applicability of our procedure is demonstrated by the trapping of RMs of acetaminophen (APAP), clozapine (CLOZ), and troglitazone (TGZ) with human glutathione-S-transferase P1-1 (hGST P1-1) as the model target protein. Clozapine 99-108 S100 calcium binding protein A10 Homo sapiens 188-192 21639118-5 2011 The applicability of our procedure is demonstrated by the trapping of RMs of acetaminophen (APAP), clozapine (CLOZ), and troglitazone (TGZ) with human glutathione-S-transferase P1-1 (hGST P1-1) as the model target protein. Troglitazone 121-133 S100 calcium binding protein A10 Homo sapiens 177-181 21639118-5 2011 The applicability of our procedure is demonstrated by the trapping of RMs of acetaminophen (APAP), clozapine (CLOZ), and troglitazone (TGZ) with human glutathione-S-transferase P1-1 (hGST P1-1) as the model target protein. Troglitazone 121-133 S100 calcium binding protein A10 Homo sapiens 188-192 21558493-1 2011 P11, a novel peptide ligand containing a PDZ-binding motif (Ser-Asp-Val) with high affinity to integrin alpha(v)beta(3) was identified from a hexapeptide library (PS-SPCL) using a protein microarray chip-based screening system. Serine 60-63 S100 calcium binding protein A10 Homo sapiens 0-3 21558493-1 2011 P11, a novel peptide ligand containing a PDZ-binding motif (Ser-Asp-Val) with high affinity to integrin alpha(v)beta(3) was identified from a hexapeptide library (PS-SPCL) using a protein microarray chip-based screening system. H-Asp-Val-OH 64-71 S100 calcium binding protein A10 Homo sapiens 0-3 21375334-0 2011 Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-one analogues as inhibitors of the annexin A2-S100A10 protein interaction. 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1h-pyrrol-2(5h)-one 70-130 S100 calcium binding protein A10 Homo sapiens 173-180 21269277-3 2011 In contrast with other S100 proteins, S100A10 is unable to bind calcium due to deletion and substitution of calcium-ligating residues. Calcium 108-115 S100 calcium binding protein A10 Homo sapiens 38-45 21269277-4 2011 Despite this, calcium-free S100A10 assumes an "open" conformation that is very similar to S100A11 in its calcium-bound state. Calcium 14-21 S100 calcium binding protein A10 Homo sapiens 27-34 21269277-4 2011 Despite this, calcium-free S100A10 assumes an "open" conformation that is very similar to S100A11 in its calcium-bound state. Calcium 105-112 S100 calcium binding protein A10 Homo sapiens 27-34 21269277-5 2011 To understand how S100A10 is able to adopt an open conformation in the absence of calcium, seven chimaeric proteins were constructed where regions from calcium-binding sites I and II, and helices II-IV in S100A11 were replaced with the corresponding regions of S100A10. Calcium 152-159 S100 calcium binding protein A10 Homo sapiens 18-25 21269277-7 2011 This response is similar to that observed for Ca2+-S100A11 and calcium-free S100A10. Calcium 63-70 S100 calcium binding protein A10 Homo sapiens 76-83 21269277-11 2011 The present study represents a first attempt to systematically understand the molecular basis for the calcium-insensitive open conformation of S100A10. Calcium 102-109 S100 calcium binding protein A10 Homo sapiens 143-150 21639118-5 2011 The applicability of our procedure is demonstrated by the trapping of RMs of acetaminophen (APAP), clozapine (CLOZ), and troglitazone (TGZ) with human glutathione-S-transferase P1-1 (hGST P1-1) as the model target protein. Acetaminophen 77-90 S100 calcium binding protein A10 Homo sapiens 177-181 21639118-5 2011 The applicability of our procedure is demonstrated by the trapping of RMs of acetaminophen (APAP), clozapine (CLOZ), and troglitazone (TGZ) with human glutathione-S-transferase P1-1 (hGST P1-1) as the model target protein. Acetaminophen 77-90 S100 calcium binding protein A10 Homo sapiens 188-192 21639118-5 2011 The applicability of our procedure is demonstrated by the trapping of RMs of acetaminophen (APAP), clozapine (CLOZ), and troglitazone (TGZ) with human glutathione-S-transferase P1-1 (hGST P1-1) as the model target protein. Acetaminophen 92-96 S100 calcium binding protein A10 Homo sapiens 177-181 21639118-5 2011 The applicability of our procedure is demonstrated by the trapping of RMs of acetaminophen (APAP), clozapine (CLOZ), and troglitazone (TGZ) with human glutathione-S-transferase P1-1 (hGST P1-1) as the model target protein. Acetaminophen 92-96 S100 calcium binding protein A10 Homo sapiens 188-192 21310922-4 2011 In the present study we show for the first time that the plasminogen receptor, S100A10, is present on the extracellular surface of APL cells and is rapidly down-regulated in response to all-trans retinoic acid. Tretinoin 196-209 S100 calcium binding protein A10 Homo sapiens 79-86 20830735-3 2010 Here we report unprecedented detection of endogenous p10, the smaller proteolytic fragment of the Cdk5 activator p35 in treated primary cortical neurons that underwent significant apoptosis, triggered by proteasome inhibitors MG132 and lactacystin, and protein kinase inhibitor staurosporine (STS). lactacystin 236-247 S100 calcium binding protein A10 Homo sapiens 53-56 20830735-3 2010 Here we report unprecedented detection of endogenous p10, the smaller proteolytic fragment of the Cdk5 activator p35 in treated primary cortical neurons that underwent significant apoptosis, triggered by proteasome inhibitors MG132 and lactacystin, and protein kinase inhibitor staurosporine (STS). Staurosporine 278-291 S100 calcium binding protein A10 Homo sapiens 53-56 20830735-3 2010 Here we report unprecedented detection of endogenous p10, the smaller proteolytic fragment of the Cdk5 activator p35 in treated primary cortical neurons that underwent significant apoptosis, triggered by proteasome inhibitors MG132 and lactacystin, and protein kinase inhibitor staurosporine (STS). Staurosporine 293-296 S100 calcium binding protein A10 Homo sapiens 53-56 20374557-8 2010 In addition, these results showed that the formation of phosphatidylinositol (4,5)-bisphosphate (PIP(2)) microdomains colocalized with S100A10 in the vicinity of docked granules, suggesting a functional interplay between annexin-A2-mediated lipid microdomains and SNAREs during exocytosis. Phosphatidylinositol 4,5-Diphosphate 56-95 S100 calcium binding protein A10 Homo sapiens 135-142 20849150-4 2010 In the present study, we studied the ability of four recombinant human GSTs (hGST A1-1, hGST M1-1, hGST P1-1, and hGST T1-1) to catalyze the GSH conjugation of reactive metabolites of clozapine, formed in vitro by human and rat liver microsomes and drug-metabolizing P450 BM3 mutant, P450 102A1M11H. Glutathione 141-144 S100 calcium binding protein A10 Homo sapiens 104-108 20937773-3 2010 In this study, we demonstrate that procaspase-8 is phosphorylated in mitotic cells by Cdk1/cyclin B1 on Ser-387, which is located at the N terminus of the catalytic subunit p10. Serine 104-107 S100 calcium binding protein A10 Homo sapiens 173-176 20374557-8 2010 In addition, these results showed that the formation of phosphatidylinositol (4,5)-bisphosphate (PIP(2)) microdomains colocalized with S100A10 in the vicinity of docked granules, suggesting a functional interplay between annexin-A2-mediated lipid microdomains and SNAREs during exocytosis. Phosphatidylinositol 4,5-Diphosphate 97-103 S100 calcium binding protein A10 Homo sapiens 135-142 19780048-1 2009 The effect of the Y108V mutation of human glutathione S-transferase P1-1 (hGST P1-1) on the binding of the diuretic drug ethacrynic acid (EA) and its glutathione conjugate (EASG) was investigated by calorimetric, spectrofluorimetric, and crystallographic studies. Ethacrynic Acid 121-136 S100 calcium binding protein A10 Homo sapiens 68-72 19995563-4 2010 Interestingly, P10-P8 but not P8 showed a novel Mg(2+) dependent ATPase activity that was inhibited in the presence of poly A. Poly A 119-125 S100 calcium binding protein A10 Homo sapiens 15-18 20085458-0 2010 A Cy5-labeled S100A10 tracer used to identify inhibitors of the protein interaction with annexin A2. cyanine dye 5 2-5 S100 calcium binding protein A10 Homo sapiens 14-21 20085458-2 2010 The interaction between the Ca2+- and phospholipid-binding protein Annexin A2 and its binding partner S100A10 has been implicated in angiogenesis and cancer metastasis. Phospholipids 38-50 S100 calcium binding protein A10 Homo sapiens 102-109 20085458-4 2010 We developed a Cy5-labeled S100A10 tracer and showed by circular dichroism spectroscopy that the secondary structure is indistinguishable from that of non-labeled S100A10. cyanine dye 5 15-18 S100 calcium binding protein A10 Homo sapiens 27-34 20085458-4 2010 We developed a Cy5-labeled S100A10 tracer and showed by circular dichroism spectroscopy that the secondary structure is indistinguishable from that of non-labeled S100A10. cyanine dye 5 15-18 S100 calcium binding protein A10 Homo sapiens 163-170 19827097-3 2009 S100A10 does not bind calcium but is able to recruit the N-terminus of annexin A2 important for membrane fusion events, and to form larger multiprotein complexes such as that with the cation channel proteins TRPV5/6. Calcium 22-29 S100 calcium binding protein A10 Homo sapiens 0-7 19780048-1 2009 The effect of the Y108V mutation of human glutathione S-transferase P1-1 (hGST P1-1) on the binding of the diuretic drug ethacrynic acid (EA) and its glutathione conjugate (EASG) was investigated by calorimetric, spectrofluorimetric, and crystallographic studies. Ethacrynic Acid 121-136 S100 calcium binding protein A10 Homo sapiens 79-83 19780048-1 2009 The effect of the Y108V mutation of human glutathione S-transferase P1-1 (hGST P1-1) on the binding of the diuretic drug ethacrynic acid (EA) and its glutathione conjugate (EASG) was investigated by calorimetric, spectrofluorimetric, and crystallographic studies. Ethacrynic Acid 138-140 S100 calcium binding protein A10 Homo sapiens 68-72 19780048-1 2009 The effect of the Y108V mutation of human glutathione S-transferase P1-1 (hGST P1-1) on the binding of the diuretic drug ethacrynic acid (EA) and its glutathione conjugate (EASG) was investigated by calorimetric, spectrofluorimetric, and crystallographic studies. Ethacrynic Acid 138-140 S100 calcium binding protein A10 Homo sapiens 79-83 19780048-1 2009 The effect of the Y108V mutation of human glutathione S-transferase P1-1 (hGST P1-1) on the binding of the diuretic drug ethacrynic acid (EA) and its glutathione conjugate (EASG) was investigated by calorimetric, spectrofluorimetric, and crystallographic studies. Glutathione 42-53 S100 calcium binding protein A10 Homo sapiens 68-72 19780048-1 2009 The effect of the Y108V mutation of human glutathione S-transferase P1-1 (hGST P1-1) on the binding of the diuretic drug ethacrynic acid (EA) and its glutathione conjugate (EASG) was investigated by calorimetric, spectrofluorimetric, and crystallographic studies. Glutathione 42-53 S100 calcium binding protein A10 Homo sapiens 79-83 19780048-1 2009 The effect of the Y108V mutation of human glutathione S-transferase P1-1 (hGST P1-1) on the binding of the diuretic drug ethacrynic acid (EA) and its glutathione conjugate (EASG) was investigated by calorimetric, spectrofluorimetric, and crystallographic studies. easg 173-177 S100 calcium binding protein A10 Homo sapiens 68-72 19780048-1 2009 The effect of the Y108V mutation of human glutathione S-transferase P1-1 (hGST P1-1) on the binding of the diuretic drug ethacrynic acid (EA) and its glutathione conjugate (EASG) was investigated by calorimetric, spectrofluorimetric, and crystallographic studies. easg 173-177 S100 calcium binding protein A10 Homo sapiens 79-83 19200876-7 2009 In hepatocytes, a small fragment, p10(BHMT), made by autophagic processing of the enzyme betaine:homocysteine methyltransferase, thus accumulates in an autophagy-dependent manner in the presence of leupeptin. leupeptin 198-207 S100 calcium binding protein A10 Homo sapiens 34-37 19880768-4 2009 Here we report a novel case of therapy-related myelodysplastic syndrome/acute myeloid leukemia associated with der(1;7)(q10;p10) in a glioblastoma multiforme patient treated with temozolomide. Temozolomide 179-191 S100 calcium binding protein A10 Homo sapiens 124-127 19880768-7 2009 However, we report a case of temozolomide-related myelodysplastic syndrome/acute myeloid leukemia with der(1;7)(q10;p10), possibly the first reported case, to the authors" knowledge. Temozolomide 29-41 S100 calcium binding protein A10 Homo sapiens 116-119 19380152-8 2009 P11 mRNA levels were positively correlated with the scores of HAMD (r=0.62, p<0.05), CDTS-F (r=0.71, p<0.05) and CDTS-S (r=0.62, p<0.05), while they did not correlate with scores of HARS and IES-R. Basal levels of plasma and salivary cortisol of PTSD patients were not statistically different from those of controls. 1,5,9-cyclododecatriene 88-92 S100 calcium binding protein A10 Homo sapiens 0-3 19380152-8 2009 P11 mRNA levels were positively correlated with the scores of HAMD (r=0.62, p<0.05), CDTS-F (r=0.71, p<0.05) and CDTS-S (r=0.62, p<0.05), while they did not correlate with scores of HARS and IES-R. Basal levels of plasma and salivary cortisol of PTSD patients were not statistically different from those of controls. 1,5,9-cyclododecatriene 119-123 S100 calcium binding protein A10 Homo sapiens 0-3 19387472-3 2009 Linkage of serum creatinine levels to loci on chromosomes 7p14, 9p21, 11p15, 15q15-21, 16p13, and 18p11 was successfully replicated in at least one discovery population or in the pooled analysis. Creatinine 17-27 S100 calcium binding protein A10 Homo sapiens 100-103 19490842-0 2009 Differential expression of glutathione S-transferases P1-1 and A1-1 at protein and mRNA levels in hepatocytes derived from human bone marrow mesenchymal stem cells. Glutathione 27-38 S100 calcium binding protein A10 Homo sapiens 54-67 19280518-0 2009 2-ABT-S-oxide detoxification by glutathione S-transferases A1-1, M1-1 and P1-1: implications for toxicity associated with zileuton. 2-(4'-diethylaminophenyl)benzothiazole 0-5 S100 calcium binding protein A10 Homo sapiens 74-78 19280518-0 2009 2-ABT-S-oxide detoxification by glutathione S-transferases A1-1, M1-1 and P1-1: implications for toxicity associated with zileuton. Oxides 6-13 S100 calcium binding protein A10 Homo sapiens 74-78 19280518-0 2009 2-ABT-S-oxide detoxification by glutathione S-transferases A1-1, M1-1 and P1-1: implications for toxicity associated with zileuton. zileuton 122-130 S100 calcium binding protein A10 Homo sapiens 74-78 20093721-8 2009 We propose that cAMP/PKA-dependent activation of chloride flux (through CFTR and ORCC) requires the mobilisation of a multi-protein complex involving calcium binding proteins from three different families (annexin 2, S100A10 and Calcineurin A). Cyclic AMP 16-20 S100 calcium binding protein A10 Homo sapiens 217-224 20093721-8 2009 We propose that cAMP/PKA-dependent activation of chloride flux (through CFTR and ORCC) requires the mobilisation of a multi-protein complex involving calcium binding proteins from three different families (annexin 2, S100A10 and Calcineurin A). Chlorides 49-57 S100 calcium binding protein A10 Homo sapiens 217-224 20093721-8 2009 We propose that cAMP/PKA-dependent activation of chloride flux (through CFTR and ORCC) requires the mobilisation of a multi-protein complex involving calcium binding proteins from three different families (annexin 2, S100A10 and Calcineurin A). Calcium 150-157 S100 calcium binding protein A10 Homo sapiens 217-224 20093722-4 2009 Translocation of heterotetrameric (A2*p11)(2) is facilitated both by src-kinase mediated phosphorylation of A2 at tyrosine 23, and by expression of and partnering with p11. Tyrosine 114-122 S100 calcium binding protein A10 Homo sapiens 38-41 19847291-5 2009 We postulated that CFTR participates in the regulation of eicosanoid release by direct interaction with a complex containing ANXA1, p11 and cPLA2alpha. Eicosanoids 58-68 S100 calcium binding protein A10 Homo sapiens 132-135 19847291-14 2009 These results show that (i) CFTR may form a complex with cPLA2alpha and ANXA1 via interaction with p11, (ii) CFTR inhibition and DRM disruption induce eicosanoid synthesis, and (iii) suggest that the putative cPLA2/ANXA1/p11/CFTR complex may participate in the modulation of the TNF-alpha-induced production of eicosanoids, pointing to the importance of membrane composition and CFTR function in the regulation of inflammation mediator synthesis. Eicosanoids 151-161 S100 calcium binding protein A10 Homo sapiens 221-224 19847291-14 2009 These results show that (i) CFTR may form a complex with cPLA2alpha and ANXA1 via interaction with p11, (ii) CFTR inhibition and DRM disruption induce eicosanoid synthesis, and (iii) suggest that the putative cPLA2/ANXA1/p11/CFTR complex may participate in the modulation of the TNF-alpha-induced production of eicosanoids, pointing to the importance of membrane composition and CFTR function in the regulation of inflammation mediator synthesis. Eicosanoids 311-322 S100 calcium binding protein A10 Homo sapiens 99-102 19011238-7 2009 Substitutions at P10 (G340P, G340S) or P8 (T342P, T342N) resulted in a partial loss of steroid binding after proteolysis which we attribute to incomplete insertion of the cleaved RCL. Steroids 87-94 S100 calcium binding protein A10 Homo sapiens 17-20 18947306-13 2008 Conversely, we identified 302 gene upregulations and 56 downregulations when comparing 21% O(2) (p0p10) with 2% O2 (p10). Oxygen 91-95 S100 calcium binding protein A10 Homo sapiens 99-102 18187190-8 2008 In conclusion, our data demonstrates that cAMP/PKA/CnA signalling is important for anx 2-S100A10 complex formation and interaction with target molecules in both absorptive and secretory epithelia. Cyclic AMP 42-46 S100 calcium binding protein A10 Homo sapiens 89-96 18612239-3 2008 Here, we show that dominant negative RhoA, Rho inhibitor C3 exoenzyme, ROCK/Rho-kinase inhibitor Y-27632 and Rac1 inhibitor NSC23766 inhibit p10-mediated cell fusion. Y 27632 97-104 S100 calcium binding protein A10 Homo sapiens 141-144 18786444-0 2008 Acute erythroleukemia with der(1;7)(q10;p10) as a sole acquired abnormality after treatment with azathioprine. Azathioprine 97-109 S100 calcium binding protein A10 Homo sapiens 40-43 18507738-4 2008 p39 and p35 contain localization motifs, such as a second Gly for myristoylation and Lys clusters in the N-terminal p10 region. Glycine 58-61 S100 calcium binding protein A10 Homo sapiens 116-119 18187190-0 2008 The annexin 2-S100A10 complex and its association with TRPV6 is regulated by cAMP/PKA/CnA in airway and gut epithelia. Cyclic AMP 77-81 S100 calcium binding protein A10 Homo sapiens 14-21 18187190-3 2008 Here we describe a cyclic 3",5"-adenosine monophosphate (cAMP) and cAMP-dependent protein kinase (PKA, EC 2.7.1.37)-dependent mechanism regulating anx 2-S100A10 complex formation and its interaction with the transient receptor potential vanilloid type 6 channel (TRPV6) in airway and gut epithelia. cyclic 3",5"-adenosine monophosphate 19-55 S100 calcium binding protein A10 Homo sapiens 153-160 18187190-3 2008 Here we describe a cyclic 3",5"-adenosine monophosphate (cAMP) and cAMP-dependent protein kinase (PKA, EC 2.7.1.37)-dependent mechanism regulating anx 2-S100A10 complex formation and its interaction with the transient receptor potential vanilloid type 6 channel (TRPV6) in airway and gut epithelia. Cyclic AMP 57-61 S100 calcium binding protein A10 Homo sapiens 153-160 18187190-3 2008 Here we describe a cyclic 3",5"-adenosine monophosphate (cAMP) and cAMP-dependent protein kinase (PKA, EC 2.7.1.37)-dependent mechanism regulating anx 2-S100A10 complex formation and its interaction with the transient receptor potential vanilloid type 6 channel (TRPV6) in airway and gut epithelia. Cyclic AMP 67-71 S100 calcium binding protein A10 Homo sapiens 153-160 18187190-4 2008 In both 16HBE14o- and Caco-2 cells, forskolin (FSK) stimulated increased anx 2-S100A10 complex formation, which was attenuated by either PKA inhibitors or calcineurin A (CnA) inhibitors. Colforsin 36-45 S100 calcium binding protein A10 Homo sapiens 79-86 18187190-4 2008 In both 16HBE14o- and Caco-2 cells, forskolin (FSK) stimulated increased anx 2-S100A10 complex formation, which was attenuated by either PKA inhibitors or calcineurin A (CnA) inhibitors. Colforsin 47-50 S100 calcium binding protein A10 Homo sapiens 79-86 18187190-5 2008 The anx 2-S100A10 complex association with TRPV6 was dependent on FSK-induced CnA-dependent dephosphorylation of anx 2. Colforsin 66-69 S100 calcium binding protein A10 Homo sapiens 10-17 18187190-7 2008 Thus, the cAMP/PKA/CnA-induced anx 2-S100A10/TRPV6 complex may require additional factors for calcium influx or play a role independent of calcium influx in airway epithelia. Cyclic AMP 10-14 S100 calcium binding protein A10 Homo sapiens 37-44 18187190-7 2008 Thus, the cAMP/PKA/CnA-induced anx 2-S100A10/TRPV6 complex may require additional factors for calcium influx or play a role independent of calcium influx in airway epithelia. Calcium 94-101 S100 calcium binding protein A10 Homo sapiens 37-44 18507738-4 2008 p39 and p35 contain localization motifs, such as a second Gly for myristoylation and Lys clusters in the N-terminal p10 region. Lysine 85-88 S100 calcium binding protein A10 Homo sapiens 116-119 18507738-8 2008 Plasma membrane targeting depends on the amino acid sequence containing the Lys-cluster in the N-terminal p10 region. Lysine 76-79 S100 calcium binding protein A10 Homo sapiens 106-109 18389276-6 2008 An N-terminal peptide that comprises 14 residues of annexin-2 and that includes the binding site for the calcium binding protein p11 strongly inhibited the fusion process. Calcium 105-112 S100 calcium binding protein A10 Homo sapiens 129-132 18434302-4 2008 Within the endothelial cell, p11 is required for Src kinase-mediated tyrosine phosphorylation of A2, which signals translocation of both proteins to the cell surface. Tyrosine 69-77 S100 calcium binding protein A10 Homo sapiens 29-32 18467305-5 2008 RESULTS: Saquinavir concentrations were below MEC at P10 for 0.7 h for twice-daily saquinavir/ritonavir when compared with 8.6 and 6.6 h for 1600/100 and 2000/100 mg once daily, respectively. Saquinavir 9-19 S100 calcium binding protein A10 Homo sapiens 53-56 18440154-3 2008 Recently, a study demonstrated that dexamethasone (Dex), a synthetic glucocorticoid, can up-regulate p11, known as S100A10-protein which is down-regulated in patients with depression, (Yao et al., 1999; Huang et al., 2003) a common comorbid disorder in PTSD. Dexamethasone 36-49 S100 calcium binding protein A10 Homo sapiens 101-104 18440154-3 2008 Recently, a study demonstrated that dexamethasone (Dex), a synthetic glucocorticoid, can up-regulate p11, known as S100A10-protein which is down-regulated in patients with depression, (Yao et al., 1999; Huang et al., 2003) a common comorbid disorder in PTSD. Dexamethasone 36-49 S100 calcium binding protein A10 Homo sapiens 115-122 18440154-3 2008 Recently, a study demonstrated that dexamethasone (Dex), a synthetic glucocorticoid, can up-regulate p11, known as S100A10-protein which is down-regulated in patients with depression, (Yao et al., 1999; Huang et al., 2003) a common comorbid disorder in PTSD. Dexamethasone 51-54 S100 calcium binding protein A10 Homo sapiens 101-104 18440154-3 2008 Recently, a study demonstrated that dexamethasone (Dex), a synthetic glucocorticoid, can up-regulate p11, known as S100A10-protein which is down-regulated in patients with depression, (Yao et al., 1999; Huang et al., 2003) a common comorbid disorder in PTSD. Dexamethasone 51-54 S100 calcium binding protein A10 Homo sapiens 115-122 18440154-6 2008 We also found that Dex up-regulated p11 expression in SH-SY5Y cells through glucocorticoid response elements (GREs) within the p11 promoter. Dexamethasone 19-22 S100 calcium binding protein A10 Homo sapiens 36-39 18440154-6 2008 We also found that Dex up-regulated p11 expression in SH-SY5Y cells through glucocorticoid response elements (GREs) within the p11 promoter. Dexamethasone 19-22 S100 calcium binding protein A10 Homo sapiens 127-130 18440154-7 2008 This response was attenuated by either RU486, a glucocorticoid receptor (GR) antagonist or mutating two of three glucocorticoid response elements (GRE2 and GRE3) in the p11 promoter. Mifepristone 39-44 S100 calcium binding protein A10 Homo sapiens 169-172 18289715-8 2008 RESULTS: Alcohol induced a significant up-regulation of ANXA2, PLG, PAI-1 and p11 in human ALD, cell lines and in mice exposed to alcohol. Alcohols 9-16 S100 calcium binding protein A10 Homo sapiens 78-81 18523262-3 2008 Herein, we demonstrate that a pan-active cathepsin inhibitor, SB-331750, attenuated the processing of whole cell Ii p10 to CLIP by Raji cells, and DBA/1, SJL/J, and C57BL/6 splenocytes. SB 331750 62-71 S100 calcium binding protein A10 Homo sapiens 116-119 18401344-4 2008 Upon oxidation of immature particles, a disulphide-linked Gag hexamer was formed, implying that p10 participates in and stabilizes the immature Gag hexamer. disulphide 40-50 S100 calcium binding protein A10 Homo sapiens 96-99 18289715-8 2008 RESULTS: Alcohol induced a significant up-regulation of ANXA2, PLG, PAI-1 and p11 in human ALD, cell lines and in mice exposed to alcohol. Alcohols 130-137 S100 calcium binding protein A10 Homo sapiens 78-81 18289715-9 2008 Up-regulation of ANXA2 and p11 was inhibited by the alcohol dehydrogenase inhibitor 4-methylpyrazole. Fomepizole 84-100 S100 calcium binding protein A10 Homo sapiens 27-30 18234212-9 2008 The resulting thermodynamic magnitudes classify the different proline residues according to their importance in the interaction as P2 approximately P7 approximately P10>P9 approximately P6>P8, which agrees well with Lim"s model for the interaction between SH3 domains and proline-rich peptides. Proline 62-69 S100 calcium binding protein A10 Homo sapiens 165-168 18234212-9 2008 The resulting thermodynamic magnitudes classify the different proline residues according to their importance in the interaction as P2 approximately P7 approximately P10>P9 approximately P6>P8, which agrees well with Lim"s model for the interaction between SH3 domains and proline-rich peptides. Proline 278-285 S100 calcium binding protein A10 Homo sapiens 165-168 18065419-3 2008 In vitro activity assays and membrane binding measurements by surface plasmon resonance analysis showed that a heterotetramer (A2t) of p11 and annexin A2, but not p11 or annexin A2 alone, directly binds cPLA(2)alpha via Ser(727), which keeps the enzyme from binding the membrane and catalyzing the phospholipid hydrolysis. Serine 220-223 S100 calcium binding protein A10 Homo sapiens 135-138 17991504-6 2008 Depolymerisation of the microtubule network with colchicine prevents formation of P10 filaments but not of P10 tubules. Colchicine 49-59 S100 calcium binding protein A10 Homo sapiens 82-85 17991504-7 2008 Colchicine treatment enhances the association of P10 with occlusion bodies. Colchicine 0-10 S100 calcium binding protein A10 Homo sapiens 49-52 18065419-3 2008 In vitro activity assays and membrane binding measurements by surface plasmon resonance analysis showed that a heterotetramer (A2t) of p11 and annexin A2, but not p11 or annexin A2 alone, directly binds cPLA(2)alpha via Ser(727), which keeps the enzyme from binding the membrane and catalyzing the phospholipid hydrolysis. Phospholipids 298-310 S100 calcium binding protein A10 Homo sapiens 135-138 18065419-5 2008 Subcellular translocation and activity measurements in HEK293 cells cotransfected with cPLA(2)alpha and p11 also showed that p11, in the form of A2t, inhibits cPLA(2)alpha by the same mechanism and that phosphorylation of Ser(727) activates cPLA(2)alpha by interfering with the inhibitory cPLA(2)alpha-A2t interaction. Serine 222-225 S100 calcium binding protein A10 Homo sapiens 125-128 18258633-8 2008 The replacement of the residues of aspartic acid in position 5 or those of alanine in position 6 in the sequence of p10mer resulted in peptides with no activity in the activation experiments. Aspartic Acid 35-48 S100 calcium binding protein A10 Homo sapiens 116-119 18258633-8 2008 The replacement of the residues of aspartic acid in position 5 or those of alanine in position 6 in the sequence of p10mer resulted in peptides with no activity in the activation experiments. Alanine 75-82 S100 calcium binding protein A10 Homo sapiens 116-119 17854767-3 2007 It was found that Tat((48-60)) showed no significant surface activity but that both P10 and Tat((48-60))P10, were highly surface active, inducing surface pressure changes of 9.7 and 8.9mNm(-1), respectively, with DMPS monolayers. Unithiol 213-217 S100 calcium binding protein A10 Homo sapiens 84-87 18068113-4 2008 To investigate this protein region in the monomeric AnxA2 and in the heterotetramer (AnxA2-p11)(2), the reactive Cys8 residue was specifically labelled with the fluorescent probe acrylodan and the interactions with membranes were studied by steady-state and time-resolved fluorescence. acrylodan 179-188 S100 calcium binding protein A10 Homo sapiens 91-94 17854767-3 2007 It was found that Tat((48-60)) showed no significant surface activity but that both P10 and Tat((48-60))P10, were highly surface active, inducing surface pressure changes of 9.7 and 8.9mNm(-1), respectively, with DMPS monolayers. Unithiol 213-217 S100 calcium binding protein A10 Homo sapiens 104-107 17937289-8 2007 Four product pathways are energetically feasible for DDVP degradation initiated by OH radicals in the atmosphere and are consistent with the experimentally observed products CCl2O and CO, but the additional products CCl2CHO, (CH3O)2P(O)OH, HO2, and a closed-shell organophosphorus compound denoted P10 are also predicted. oh radicals 83-94 S100 calcium binding protein A10 Homo sapiens 298-301 17587159-4 2007 Moreover, on SDS-polyacrylamide gel electrophoresis (SDS-PAGE) under nonreducing conditions, hexahistidine-tagged hGST P1-1 (His(6)-hGST P1-1) treated with 1 mM H(2)O(2) showed at least three extra bands, in addition to the native His(6)-hGST P1-1 subunit band. Histidine 125-128 S100 calcium binding protein A10 Homo sapiens 119-123 17587159-0 2007 Expression, purification and functional analysis of hexahistidine-tagged human glutathione S-transferase P1-1 and its cysteinyl mutants. His-His-His-His-His-His 52-65 S100 calcium binding protein A10 Homo sapiens 105-109 17587159-4 2007 Moreover, on SDS-polyacrylamide gel electrophoresis (SDS-PAGE) under nonreducing conditions, hexahistidine-tagged hGST P1-1 (His(6)-hGST P1-1) treated with 1 mM H(2)O(2) showed at least three extra bands, in addition to the native His(6)-hGST P1-1 subunit band. Water 161-166 S100 calcium binding protein A10 Homo sapiens 119-123 17587159-1 2007 The bacterial expression and purification of human glutathione S-transferase P1-1(hGST P1-1), as a hexahistidine-tagged polypeptide was performed. His-His-His-His-His-His 99-112 S100 calcium binding protein A10 Homo sapiens 77-81 17587159-4 2007 Moreover, on SDS-polyacrylamide gel electrophoresis (SDS-PAGE) under nonreducing conditions, hexahistidine-tagged hGST P1-1 (His(6)-hGST P1-1) treated with 1 mM H(2)O(2) showed at least three extra bands, in addition to the native His(6)-hGST P1-1 subunit band. Histidine 231-234 S100 calcium binding protein A10 Homo sapiens 119-123 17587159-4 2007 Moreover, on SDS-polyacrylamide gel electrophoresis (SDS-PAGE) under nonreducing conditions, hexahistidine-tagged hGST P1-1 (His(6)-hGST P1-1) treated with 1 mM H(2)O(2) showed at least three extra bands, in addition to the native His(6)-hGST P1-1 subunit band. Sodium Dodecyl Sulfate 13-16 S100 calcium binding protein A10 Homo sapiens 119-123 17587159-4 2007 Moreover, on SDS-polyacrylamide gel electrophoresis (SDS-PAGE) under nonreducing conditions, hexahistidine-tagged hGST P1-1 (His(6)-hGST P1-1) treated with 1 mM H(2)O(2) showed at least three extra bands, in addition to the native His(6)-hGST P1-1 subunit band. polyacrylamide 17-31 S100 calcium binding protein A10 Homo sapiens 119-123 17695432-1 2007 BACKGROUND: S100A10, a member of the S100 family, forms a heterotetramer with annexin IIH and promotes carcinoma invasion and metastasis by plasminogen activation. annexin iih 78-89 S100 calcium binding protein A10 Homo sapiens 12-19 17587159-4 2007 Moreover, on SDS-polyacrylamide gel electrophoresis (SDS-PAGE) under nonreducing conditions, hexahistidine-tagged hGST P1-1 (His(6)-hGST P1-1) treated with 1 mM H(2)O(2) showed at least three extra bands, in addition to the native His(6)-hGST P1-1 subunit band. Sodium Dodecyl Sulfate 53-56 S100 calcium binding protein A10 Homo sapiens 119-123 17587159-4 2007 Moreover, on SDS-polyacrylamide gel electrophoresis (SDS-PAGE) under nonreducing conditions, hexahistidine-tagged hGST P1-1 (His(6)-hGST P1-1) treated with 1 mM H(2)O(2) showed at least three extra bands, in addition to the native His(6)-hGST P1-1 subunit band. His-His-His-His-His-His 93-106 S100 calcium binding protein A10 Homo sapiens 119-123 17579622-3 2007 Four family members (S100A2, S100A4, S100A6 and S100A10) demonstrated evidence of upregulated expression in multiple medulloblastoma cell lines, following treatment with the DNA methyltransferase inhibitor, 5"-aza-2"-deoxycytidine. Decitabine 207-230 S100 calcium binding protein A10 Homo sapiens 48-55 17442443-4 2007 The oligomerization property of P10 was further investigated using chemical cross-linking with purified recombinant P10 proteins expressed in a baculovirus expression system and glutaraldehyde. Glutaral 178-192 S100 calcium binding protein A10 Homo sapiens 32-35 17442443-7 2007 Polyacrylamide gel electrophoresis under reducing or non-reducing conditions suggested that P10 subunits were oligomerized not through intermolecular disulfide bonds, but perhaps through some other type of association, such as hydrophobic or charge interactions. polyacrylamide 0-14 S100 calcium binding protein A10 Homo sapiens 92-95 17442443-7 2007 Polyacrylamide gel electrophoresis under reducing or non-reducing conditions suggested that P10 subunits were oligomerized not through intermolecular disulfide bonds, but perhaps through some other type of association, such as hydrophobic or charge interactions. Disulfides 150-159 S100 calcium binding protein A10 Homo sapiens 92-95 17046132-4 2007 Using 1-chloro-2,4 dinitrobenzene (CDNB) as a substrate, ellagic acid and curcumin were shown to inhibit GSTs A1-1, A2-2, M1-1, M2-2 and P1-1 with IC(50) values ranging from 0.04 to 5 microM whilst genistein, kaempferol and quercetin inhibited GSTs M1-1 and M2-2 only. Curcumin 74-82 S100 calcium binding protein A10 Homo sapiens 137-141 16914198-5 2007 The calcium sensitivity of annexin 2 increased further following co-expression with S100A10. Calcium 4-11 S100 calcium binding protein A10 Homo sapiens 84-91 17046132-4 2007 Using 1-chloro-2,4 dinitrobenzene (CDNB) as a substrate, ellagic acid and curcumin were shown to inhibit GSTs A1-1, A2-2, M1-1, M2-2 and P1-1 with IC(50) values ranging from 0.04 to 5 microM whilst genistein, kaempferol and quercetin inhibited GSTs M1-1 and M2-2 only. Dinitrochlorobenzene 6-33 S100 calcium binding protein A10 Homo sapiens 137-141 17046132-7 2007 Ellagic acid and curcumin also showed time- and concentration-dependent inactivation of GSTs M1-1, M2-2 and P1-1 with curcumin being a more potent inactivator than ellagic acid. Ellagic Acid 0-12 S100 calcium binding protein A10 Homo sapiens 108-112 17046132-4 2007 Using 1-chloro-2,4 dinitrobenzene (CDNB) as a substrate, ellagic acid and curcumin were shown to inhibit GSTs A1-1, A2-2, M1-1, M2-2 and P1-1 with IC(50) values ranging from 0.04 to 5 microM whilst genistein, kaempferol and quercetin inhibited GSTs M1-1 and M2-2 only. Dinitrochlorobenzene 35-39 S100 calcium binding protein A10 Homo sapiens 137-141 17046132-4 2007 Using 1-chloro-2,4 dinitrobenzene (CDNB) as a substrate, ellagic acid and curcumin were shown to inhibit GSTs A1-1, A2-2, M1-1, M2-2 and P1-1 with IC(50) values ranging from 0.04 to 5 microM whilst genistein, kaempferol and quercetin inhibited GSTs M1-1 and M2-2 only. Ellagic Acid 57-69 S100 calcium binding protein A10 Homo sapiens 137-141 17046132-7 2007 Ellagic acid and curcumin also showed time- and concentration-dependent inactivation of GSTs M1-1, M2-2 and P1-1 with curcumin being a more potent inactivator than ellagic acid. Curcumin 17-25 S100 calcium binding protein A10 Homo sapiens 108-112 17046132-7 2007 Ellagic acid and curcumin also showed time- and concentration-dependent inactivation of GSTs M1-1, M2-2 and P1-1 with curcumin being a more potent inactivator than ellagic acid. Curcumin 118-126 S100 calcium binding protein A10 Homo sapiens 108-112 17046132-7 2007 Ellagic acid and curcumin also showed time- and concentration-dependent inactivation of GSTs M1-1, M2-2 and P1-1 with curcumin being a more potent inactivator than ellagic acid. Ellagic Acid 164-176 S100 calcium binding protein A10 Homo sapiens 108-112 16973243-7 2007 When forskolin-stimulated cAMP levels were measured, P11 was inactive in this negatively coupled system. Colforsin 5-14 S100 calcium binding protein A10 Homo sapiens 53-56 17052983-6 2006 SDS-PAGE of isolated complexes showed near complete loss of the p10 subunit from initiator caspases 1 and 8 but not from the executioner caspase-6. Sodium Dodecyl Sulfate 0-3 S100 calcium binding protein A10 Homo sapiens 64-67 16737912-5 2006 Among five patients receiving more than 2 g of melphalan, three developed MDS, and two of them showed der(1;7)(q10;p10) before or at the time of MDS diagnosis. Melphalan 47-56 S100 calcium binding protein A10 Homo sapiens 115-118 16802828-6 2006 Saturation Transfer Difference (STD) NMR with one of these inhibitors, with linker structure (Asp-Gly-AMAB-Gly-Asp) and K(D) = 42 nM for GSTA1-1, demonstrates that the Asp-Gly linker interacts tightly with GSTA1-1, but not P1-1. amab-gly-asp 102-114 S100 calcium binding protein A10 Homo sapiens 223-227 15994767-2 2005 Nuclear export of Gag is crucial for the efficient production of viral particles and is accomplished through the action of a leptomycin B (LMB)-dependent nuclear export signal (NES) in the p10 domain (L. Z. Scheifele, R. A. Garbitt, J. D. Rhoads, and L. J. leptomycin B 125-137 S100 calcium binding protein A10 Homo sapiens 189-192 16373665-4 2006 Binding of plasmin to annexin A2 and S100A10 on monocytes was verified by biotin transfer from plasmin labeled with a trifunctional cross-linker. Biotin 74-80 S100 calcium binding protein A10 Homo sapiens 37-44 16373665-6 2006 Further, down-regulation of annexin A2 or S100A10 in monocytes by antisense oligodeoxynucleotides impaired the chemotactic response to plasmin, but not that to fMLP. Oligodeoxyribonucleotides 76-97 S100 calcium binding protein A10 Homo sapiens 42-49 16321399-5 2006 We show here that introduction of a P10 sequence C-terminal to polyGln in synthetic peptides decreases both the rate of formation and the apparent stability of the amyloid-like aggregates associated with this family of diseases. polyglutamine 63-70 S100 calcium binding protein A10 Homo sapiens 36-39 16321399-5 2006 We show here that introduction of a P10 sequence C-terminal to polyGln in synthetic peptides decreases both the rate of formation and the apparent stability of the amyloid-like aggregates associated with this family of diseases. Peptides 84-92 S100 calcium binding protein A10 Homo sapiens 36-39 16321399-8 2006 There is no suppression, however, when the P10 sequence is either placed on the N-terminal side of polyGln or attached to polyGln via a side-chain tether. polyglutamine 99-106 S100 calcium binding protein A10 Homo sapiens 43-46 16321399-8 2006 There is no suppression, however, when the P10 sequence is either placed on the N-terminal side of polyGln or attached to polyGln via a side-chain tether. polyglutamine 122-129 S100 calcium binding protein A10 Homo sapiens 43-46 16230353-0 2005 Phosphoinositide specificity of and mechanism of lipid domain formation by annexin A2-p11 heterotetramer. Phosphatidylinositols 0-16 S100 calcium binding protein A10 Homo sapiens 86-89 16230353-1 2005 Annexin A2 is a phospholipid-binding protein that forms a heterotetramer (annexin II-p11 heterotetramer; A2t) with p11 (S100A10). Phospholipids 16-28 S100 calcium binding protein A10 Homo sapiens 85-88 16230353-1 2005 Annexin A2 is a phospholipid-binding protein that forms a heterotetramer (annexin II-p11 heterotetramer; A2t) with p11 (S100A10). Phospholipids 16-28 S100 calcium binding protein A10 Homo sapiens 115-118 16085316-4 2006 NADPH-d activity in the superficial layer of the spinal cord increased gradually with ages from P10 to P30 and NMDA enhanced the NADPH-d staining in a time- and concentration-dependent manner. NADP 0-5 S100 calcium binding protein A10 Homo sapiens 96-99 16085316-4 2006 NADPH-d activity in the superficial layer of the spinal cord increased gradually with ages from P10 to P30 and NMDA enhanced the NADPH-d staining in a time- and concentration-dependent manner. N-Methylaspartate 111-115 S100 calcium binding protein A10 Homo sapiens 96-99 16853517-6 2005 Hypericin binds with high affinity to the GSTs: 0.65 microM for the A1-1 isoform and 0.51 microM for the P1-1 isoform (Biochemistry 2004, 43, 12761-12769). hypericin 0-9 S100 calcium binding protein A10 Homo sapiens 105-109 16853517-10 2005 The data are rationalized in terms of a simple model in which the hypericin photophysics depends entirely upon the decay of the triplet state by two competing processes, quenching by oxygen to yield singlet oxygen and ionization, the latter of these two are proposed to be modulated by A1-1 and P1-1. hypericin 66-75 S100 calcium binding protein A10 Homo sapiens 295-299 15994767-2 2005 Nuclear export of Gag is crucial for the efficient production of viral particles and is accomplished through the action of a leptomycin B (LMB)-dependent nuclear export signal (NES) in the p10 domain (L. Z. Scheifele, R. A. Garbitt, J. D. Rhoads, and L. J. leptomycin B 139-142 S100 calcium binding protein A10 Homo sapiens 189-192 15794635-10 2005 Activity assays show that ATP and dATP, but not ADP or AMP, bind to the processed Csp9 p35/p10. Adenosine Triphosphate 26-29 S100 calcium binding protein A10 Homo sapiens 91-94 15794635-10 2005 Activity assays show that ATP and dATP, but not ADP or AMP, bind to the processed Csp9 p35/p10. 2'-deoxyadenosine triphosphate 34-38 S100 calcium binding protein A10 Homo sapiens 91-94 15574370-8 2005 The carboxyl-terminal lysines of S100A10 bind tPA and plasminogen resulting in the stimulation of tPA-dependent plasmin production. Lysine 22-29 S100 calcium binding protein A10 Homo sapiens 33-40 15574370-8 2005 The carboxyl-terminal lysines of S100A10 bind tPA and plasminogen resulting in the stimulation of tPA-dependent plasmin production. Tetradecanoylphorbol Acetate 46-49 S100 calcium binding protein A10 Homo sapiens 33-40 15574370-8 2005 The carboxyl-terminal lysines of S100A10 bind tPA and plasminogen resulting in the stimulation of tPA-dependent plasmin production. Tetradecanoylphorbol Acetate 98-101 S100 calcium binding protein A10 Homo sapiens 33-40 15574370-9 2005 Carboxypeptidases cleave the carboxyl-terminal lysines of S100A10, resulting in a loss of binding and activity. Lysine 47-54 S100 calcium binding protein A10 Homo sapiens 58-65 15574370-11 2005 The binding of tPA and plasmin to S100A10 also protects against inhibition by physiological inhibitors, PAI-1 and alpha2-antiplasmin, respectively. Tetradecanoylphorbol Acetate 15-18 S100 calcium binding protein A10 Homo sapiens 34-41 15302870-12 2004 Temperature stress-induced annexin 2 translocation is dependent on both expression of protein p11 (S100A10) and tyrosine phosphorylation of annexin 2 because annexin 2 release is completely eliminated on depletion of p11, inactivation of tyrosine kinase, or mutation of tyrosine 23. Tyrosine 238-246 S100 calcium binding protein A10 Homo sapiens 217-220 15347687-1 2004 Benzyl isothiocyanate (BITC), present in cruciferous vegetables, is an efficient substrate of human glutathione S-transferase P1-1 (hGST P1-1). benzyl isothiocyanate 0-21 S100 calcium binding protein A10 Homo sapiens 126-130 15347687-1 2004 Benzyl isothiocyanate (BITC), present in cruciferous vegetables, is an efficient substrate of human glutathione S-transferase P1-1 (hGST P1-1). benzyl isothiocyanate 0-21 S100 calcium binding protein A10 Homo sapiens 137-141 15347687-1 2004 Benzyl isothiocyanate (BITC), present in cruciferous vegetables, is an efficient substrate of human glutathione S-transferase P1-1 (hGST P1-1). benzyl isothiocyanate 23-27 S100 calcium binding protein A10 Homo sapiens 126-130 15347687-1 2004 Benzyl isothiocyanate (BITC), present in cruciferous vegetables, is an efficient substrate of human glutathione S-transferase P1-1 (hGST P1-1). benzyl isothiocyanate 23-27 S100 calcium binding protein A10 Homo sapiens 137-141 15347687-11 2004 This study provides evidence for the existence of a novel xenobiotic substrate site in hGST P1-1, which can be occupied by benzyl isothiocyanate and is distinct from that of monobromobimane and 1-chloro-2,4 dinitrobenzene. benzyl isothiocyanate 123-144 S100 calcium binding protein A10 Homo sapiens 92-96 15347687-11 2004 This study provides evidence for the existence of a novel xenobiotic substrate site in hGST P1-1, which can be occupied by benzyl isothiocyanate and is distinct from that of monobromobimane and 1-chloro-2,4 dinitrobenzene. monobromobimane 174-189 S100 calcium binding protein A10 Homo sapiens 92-96 15347687-11 2004 This study provides evidence for the existence of a novel xenobiotic substrate site in hGST P1-1, which can be occupied by benzyl isothiocyanate and is distinct from that of monobromobimane and 1-chloro-2,4 dinitrobenzene. Dinitrochlorobenzene 194-221 S100 calcium binding protein A10 Homo sapiens 92-96 15597303-6 2004 These results indicate that diospyrin is a potent inhibitor of heterologously expressed human GSTs A1-1, M1-1 and P1-1. diospyrin 28-37 S100 calcium binding protein A10 Homo sapiens 114-118 15597303-7 2004 Diospyrin and geshoidin were also found to inactivate P1-1 with diospyrin being a potent inactivator. diospyrin 0-9 S100 calcium binding protein A10 Homo sapiens 54-58 15597303-7 2004 Diospyrin and geshoidin were also found to inactivate P1-1 with diospyrin being a potent inactivator. geshoidin 14-23 S100 calcium binding protein A10 Homo sapiens 54-58 15597303-7 2004 Diospyrin and geshoidin were also found to inactivate P1-1 with diospyrin being a potent inactivator. diospyrin 64-73 S100 calcium binding protein A10 Homo sapiens 54-58 15597303-9 2004 Ergothioneine inactivated P1-1 only after preincubation and it enhanced ethacrynic acid inactivation of P1-1. Ergothioneine 0-13 S100 calcium binding protein A10 Homo sapiens 26-30 15597303-9 2004 Ergothioneine inactivated P1-1 only after preincubation and it enhanced ethacrynic acid inactivation of P1-1. Ergothioneine 0-13 S100 calcium binding protein A10 Homo sapiens 104-108 15597303-9 2004 Ergothioneine inactivated P1-1 only after preincubation and it enhanced ethacrynic acid inactivation of P1-1. Ethacrynic Acid 72-87 S100 calcium binding protein A10 Homo sapiens 104-108 15597303-10 2004 Inactivation of P1-1 by ergothioneine may have implications for the antioxidant roles of P1-1 and ergothioneine in vivo. Ergothioneine 24-37 S100 calcium binding protein A10 Homo sapiens 16-20 15597303-10 2004 Inactivation of P1-1 by ergothioneine may have implications for the antioxidant roles of P1-1 and ergothioneine in vivo. Ergothioneine 24-37 S100 calcium binding protein A10 Homo sapiens 89-93 15597303-10 2004 Inactivation of P1-1 by ergothioneine may have implications for the antioxidant roles of P1-1 and ergothioneine in vivo. Ergothioneine 98-111 S100 calcium binding protein A10 Homo sapiens 16-20 15461448-10 2004 A peptide "trap" of diffusive ROS was oxidized extensively upon irradiation of HYP in the presence of albumin but very little in the presence of P1-1 or A1-1. Reactive Oxygen Species 30-33 S100 calcium binding protein A10 Homo sapiens 145-157 14618086-2 2003 This ORF encodes a 10-kDa protein (p10) carrying two distinct domains: a basic, arginine-rich domain and a zinc-finger domain. Arginine 80-88 S100 calcium binding protein A10 Homo sapiens 35-38 14698669-5 2003 When microtubules were depolymerised with the drug nocodazole, P10 tubules failed to form and the protein appeared concentrated in cytoplasmic foci. Nocodazole 51-61 S100 calcium binding protein A10 Homo sapiens 63-66 15489166-4 2004 The structure of HLA-DR1 in complex with the tighter binding peptide shows that the peptide binds in the usual polyproline type II conformation, but with the P10 residue accommodated in a shallow pocket at the end of the binding groove. polyproline 111-122 S100 calcium binding protein A10 Homo sapiens 158-161 14990700-3 2004 We now show that a region of moderate hydrophobicity we call the hydrophobic patch (HP), present in the small N-terminal ectodomain of p10, shares the following characteristics with the fusion peptides of enveloped virus fusion proteins: (i) an abundance of glycine and alanine residues, (ii) a potential amphipathic secondary structure, (iii) membrane-seeking characteristics that correspond to the degree of hydrophobicity, and (iv) the ability to induce lipid mixing in a liposome fusion assay. Glycine 258-265 S100 calcium binding protein A10 Homo sapiens 135-138 14990700-3 2004 We now show that a region of moderate hydrophobicity we call the hydrophobic patch (HP), present in the small N-terminal ectodomain of p10, shares the following characteristics with the fusion peptides of enveloped virus fusion proteins: (i) an abundance of glycine and alanine residues, (ii) a potential amphipathic secondary structure, (iii) membrane-seeking characteristics that correspond to the degree of hydrophobicity, and (iv) the ability to induce lipid mixing in a liposome fusion assay. Alanine 270-277 S100 calcium binding protein A10 Homo sapiens 135-138 14990700-5 2004 Mutational and biophysical analysis suggested that the internal fusion peptide of p10 lacks alpha-helical content and exists as a disulfide-stabilized loop structure. Disulfides 130-139 S100 calcium binding protein A10 Homo sapiens 82-85 12724354-5 2003 An effect on the fibrinolysis pathway after treatment of HUVECs with thrombin was shown by increased fluorescein-labeled plasminogen binding to cells, which was inhibited by an antibody specific for p11. Fluorescein 101-112 S100 calcium binding protein A10 Homo sapiens 199-202 12730231-0 2003 Phospholipid-associated annexin A2-S100A10 heterotetramer and its subunits: characterization of the interaction with tissue plasminogen activator, plasminogen, and plasmin. Phospholipids 0-12 S100 calcium binding protein A10 Homo sapiens 35-42 12730231-9 2003 Removal of the carboxyl-terminal lysines from the S100A10 subunit attenuated t-PA and plasminogen binding to AIIt. Lysine 33-40 S100 calcium binding protein A10 Homo sapiens 50-57 12730231-10 2003 These results show that the carboxyl-terminal lysines of S100A10 form t-PA and plasminogen-binding sites. Lysine 46-53 S100 calcium binding protein A10 Homo sapiens 57-64 12941885-0 2003 Palmitoylation, membrane-proximal basic residues, and transmembrane glycine residues in the reovirus p10 protein are essential for syncytium formation. Glycine 68-75 S100 calcium binding protein A10 Homo sapiens 101-104 12941885-3 2003 We now show that the p10 dicysteine motif is palmitoylated and that loss of palmitoylation correlates with a loss of fusion activity. Cystine 25-35 S100 calcium binding protein A10 Homo sapiens 21-24 12941885-4 2003 Mutational and functional analyses also revealed that a triglycine motif within the transmembrane domain and the membrane-proximal basic region were essential for p10-mediated membrane fusion. glycyl-glycyl-glycine 56-66 S100 calcium binding protein A10 Homo sapiens 163-166 12591943-4 2003 Guanosine binding is accelerated by addition of residues that form helices, referred to as P9.0 and P10, immediately 5" and 3" to the guanosine. Guanosine 0-9 S100 calcium binding protein A10 Homo sapiens 100-103 12660155-4 2003 Of these five amino acids, the first threonine plays a crucial role since the corresponding mutants (TRPV5 T599A and TRPV6 T600A) exhibited a diminished capacity to bind S100A10, were redistributed to a subplasma membrane area and did not display channel activity. Threonine 37-46 S100 calcium binding protein A10 Homo sapiens 170-177 12506111-7 2003 We have found that cleavage of procaspase-9 at Asp(330) to generate p35, p10 or p37, p10 forms resulted in a significant increase (up to 8-fold) in apoptosome activity compared with p35/p12. Aspartic Acid 47-50 S100 calcium binding protein A10 Homo sapiens 73-76 12506111-7 2003 We have found that cleavage of procaspase-9 at Asp(330) to generate p35, p10 or p37, p10 forms resulted in a significant increase (up to 8-fold) in apoptosome activity compared with p35/p12. Aspartic Acid 47-50 S100 calcium binding protein A10 Homo sapiens 85-88 12506111-9 2003 In addition, cleavage at Asp(330) exposed a novel p10 NH(2)-terminal peptide motif (AISS) that retained the ability to mediate XIAP inhibition of caspase-9. Aspartic Acid 25-28 S100 calcium binding protein A10 Homo sapiens 50-53 12591943-4 2003 Guanosine binding is accelerated by addition of residues that form helices, referred to as P9.0 and P10, immediately 5" and 3" to the guanosine. Guanosine 134-143 S100 calcium binding protein A10 Homo sapiens 100-103 12591943-6 2003 Because the ability to form the P9.0 and P10 helices distinguishes the guanosine at the correct 3"-splice site from other guanosine residues, the faster binding of the correct guanosine can enhance specificity of 3"-splice site selection. Guanosine 71-80 S100 calcium binding protein A10 Homo sapiens 41-44 12591943-6 2003 Because the ability to form the P9.0 and P10 helices distinguishes the guanosine at the correct 3"-splice site from other guanosine residues, the faster binding of the correct guanosine can enhance specificity of 3"-splice site selection. Guanosine 122-131 S100 calcium binding protein A10 Homo sapiens 41-44 12591943-6 2003 Because the ability to form the P9.0 and P10 helices distinguishes the guanosine at the correct 3"-splice site from other guanosine residues, the faster binding of the correct guanosine can enhance specificity of 3"-splice site selection. Guanosine 122-131 S100 calcium binding protein A10 Homo sapiens 41-44 12524083-0 2003 Glutathione and glutathione S-transferases A1-1 and P1-1 in seminal plasma may play a role in protecting against oxidative damage to spermatozoa. Glutathione 16-27 S100 calcium binding protein A10 Homo sapiens 52-56 12414796-0 2003 Contribution of glycine 146 to a conserved folding module affecting stability and refolding of human glutathione transferase p1-1. Glycine 16-23 S100 calcium binding protein A10 Homo sapiens 125-129 12466433-4 2002 We found that the rate of GABA(A,slow) sIPSCs increased by over 70-fold between P11 and P35 (from 0.0017 to 0.12 s(-1)). gamma-Aminobutyric Acid 26-30 S100 calcium binding protein A10 Homo sapiens 80-91 12460893-5 2002 Interestingly, five calcium-binding proteins (S100A2, S100A7, S100A8, S100A9, and S100A10) were overexpressed. Calcium 20-27 S100 calcium binding protein A10 Homo sapiens 82-89 12444967-5 2002 Kinetic analysis of these ribozyme variants demonstrated the importance of the two W-C base pairs of P1.1 for cleavage; in addition, the results suggest that all hydrogen bond interactions detected in the crystal structure involving 2"-OH and N7 atoms are present in the active ribozyme structure. Hydrogen 162-170 S100 calcium binding protein A10 Homo sapiens 101-105 12466433-10 2002 These observations suggest differential developmental regulation of the firing properties of GABA(A,fast) and GABA(A,slow) interneurons in CA1 between P10 and P35. gamma-Aminobutyric Acid 93-97 S100 calcium binding protein A10 Homo sapiens 151-154 12466433-10 2002 These observations suggest differential developmental regulation of the firing properties of GABA(A,fast) and GABA(A,slow) interneurons in CA1 between P10 and P35. gamma-Aminobutyric Acid 110-114 S100 calcium binding protein A10 Homo sapiens 151-154 12198146-6 2002 This association with p11 requires the integrity of the last three C-terminal amino acids, Ser-Ser-Val, in TASK-1. Ser-Ser-Val 91-102 S100 calcium binding protein A10 Homo sapiens 22-25 12163506-1 2002 p11, a member of the S-100 family of proteins, is the cellular ligand of annexin II and also interacts with the C-terminal region of cytosolic phospholipase A(2) (cPLA(2)), inhibiting cPLA(2) activity and arachidonic acid (AA) release. Arachidonic Acid 205-221 S100 calcium binding protein A10 Homo sapiens 0-3 12163506-1 2002 p11, a member of the S-100 family of proteins, is the cellular ligand of annexin II and also interacts with the C-terminal region of cytosolic phospholipase A(2) (cPLA(2)), inhibiting cPLA(2) activity and arachidonic acid (AA) release. Arachidonic Acid 205-221 S100 calcium binding protein A10 Homo sapiens 54-83 12163506-7 2002 AG 1478 (EGF receptor tyrosine kinase inhibitor), PD 98059 (ERK1/2 inhibitor), and SB 203580 (p38 inhibitor) significantly inhibited EGF-induced p11 expression. RTKI cpd 0-7 S100 calcium binding protein A10 Homo sapiens 145-148 12163506-7 2002 AG 1478 (EGF receptor tyrosine kinase inhibitor), PD 98059 (ERK1/2 inhibitor), and SB 203580 (p38 inhibitor) significantly inhibited EGF-induced p11 expression. SB 203580 83-92 S100 calcium binding protein A10 Homo sapiens 145-148 12163506-9 2002 Methyl arachidonyl fluorophosphate (50 microm) also significantly inhibited EGF-induced p11 expression, demonstrating that the activation of cPLA(2) may have a role in the EGF-induced p11 expression. (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenyl methyl phosphorofluoridate 0-34 S100 calcium binding protein A10 Homo sapiens 88-91 12163506-9 2002 Methyl arachidonyl fluorophosphate (50 microm) also significantly inhibited EGF-induced p11 expression, demonstrating that the activation of cPLA(2) may have a role in the EGF-induced p11 expression. (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenyl methyl phosphorofluoridate 0-34 S100 calcium binding protein A10 Homo sapiens 184-187 12198146-8 2002 p11 association with the TASK-1 channel masks an endoplasmic reticulum retention signal identified as Lys-Arg-Arg that precedes the Ser-Ser-Val sequence. Lys-Arg-Arg 102-113 S100 calcium binding protein A10 Homo sapiens 0-3 12198146-8 2002 p11 association with the TASK-1 channel masks an endoplasmic reticulum retention signal identified as Lys-Arg-Arg that precedes the Ser-Ser-Val sequence. Serine 132-135 S100 calcium binding protein A10 Homo sapiens 0-3 12198146-8 2002 p11 association with the TASK-1 channel masks an endoplasmic reticulum retention signal identified as Lys-Arg-Arg that precedes the Ser-Ser-Val sequence. Serine 136-139 S100 calcium binding protein A10 Homo sapiens 0-3 12198146-8 2002 p11 association with the TASK-1 channel masks an endoplasmic reticulum retention signal identified as Lys-Arg-Arg that precedes the Ser-Ser-Val sequence. Valine 140-143 S100 calcium binding protein A10 Homo sapiens 0-3 12105900-10 2002 Therefore, in the present study, we attempted to determine by (31)P NMR spectroscopy whether a Cd(2+) ion binds to the P1.1 phosphorothioate at the cleavage site in solution. phosphorus-31 atom 62-67 S100 calcium binding protein A10 Homo sapiens 119-123 12145057-11 2002 Heart rate response to atropine 10 microg/kg was attenuated in Groups P-5 (12 +/- 7 bpm) and P-10 (9 +/- 6 bpm) compared with the control group (28 +/- 13 bpm, P<0.05). Atropine 23-31 S100 calcium binding protein A10 Homo sapiens 93-97 12145057-12 2002 When atropine 20 microg/kg was administered, HR increased >20 bpm in all patients of the control group, but in only 43% and 13% of patients in Groups P-5 and P-10, respectively (P<0.05). Atropine 5-13 S100 calcium binding protein A10 Homo sapiens 161-165 12105900-10 2002 Therefore, in the present study, we attempted to determine by (31)P NMR spectroscopy whether a Cd(2+) ion binds to the P1.1 phosphorothioate at the cleavage site in solution. Parathion 124-140 S100 calcium binding protein A10 Homo sapiens 119-123 12105900-14 2002 These observations support the results of our kinetic analysis and indicate that a Cd(2+) ion interacts with the sulfur atom of the phosphorothioate at the A9/G10.1 site (P9) but that a Cd(2+) ion does not interact with the sulfur atom at the Rp- or at the Sp-position of the scissile phosphate (P1.1) in the ground state. Sulfur 113-119 S100 calcium binding protein A10 Homo sapiens 296-300 12105900-14 2002 These observations support the results of our kinetic analysis and indicate that a Cd(2+) ion interacts with the sulfur atom of the phosphorothioate at the A9/G10.1 site (P9) but that a Cd(2+) ion does not interact with the sulfur atom at the Rp- or at the Sp-position of the scissile phosphate (P1.1) in the ground state. Parathion 132-148 S100 calcium binding protein A10 Homo sapiens 296-300 12031293-2 2002 In the current work, the conjugation of 13-OXO by human glutathione transferases (GSTs) of the alpha (A1-1, A4-4), mu (M1-1, M2-2) and pi (the allelic variants P1-1/ile, and P1-1/val) classes, and a rat theta (rT2-2) class enzyme has been evaluated. 13-oxo 40-46 S100 calcium binding protein A10 Homo sapiens 160-164 12175872-8 2002 We have further demonstrated that antagonists of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) glutamate receptor subtype block white matter injury at P7 and seizures at P10. -amino-3-hydroxy-5-methyl-4-isoxazole propionic 58-105 S100 calcium binding protein A10 Homo sapiens 193-196 12031293-2 2002 In the current work, the conjugation of 13-OXO by human glutathione transferases (GSTs) of the alpha (A1-1, A4-4), mu (M1-1, M2-2) and pi (the allelic variants P1-1/ile, and P1-1/val) classes, and a rat theta (rT2-2) class enzyme has been evaluated. 13-oxo 40-46 S100 calcium binding protein A10 Homo sapiens 174-178 11939791-1 2002 The Ca(2+)-dependent phospholipid-binding protein annexin II heterotetramer (AIIt) is composed of two copies of annexin II and a p11 dimer. Phospholipids 21-33 S100 calcium binding protein A10 Homo sapiens 129-132 12097194-17 2002 Using an ELISA approach, we found that Tg in OT from three TAO patients (P10, P11, and P12) contained thyroxine (T4) residues (mean T(4) CONTENT: 2.42 molecules per molecule of Tg), indicating that Tg had originated in the thyroid. Thyroxine 102-111 S100 calcium binding protein A10 Homo sapiens 73-76 11939791-2 2002 The interaction of the carboxyl-terminal lysine residues of the p11 subunit of AIIt with the lysine-binding kringle domains of plasminogen is believed to play a key role in plasminogen binding and stimulation of the tPA-catalyzed cleavage of plasminogen to plasmin. Lysine 41-47 S100 calcium binding protein A10 Homo sapiens 64-67 11939791-2 2002 The interaction of the carboxyl-terminal lysine residues of the p11 subunit of AIIt with the lysine-binding kringle domains of plasminogen is believed to play a key role in plasminogen binding and stimulation of the tPA-catalyzed cleavage of plasminogen to plasmin. Lysine 93-99 S100 calcium binding protein A10 Homo sapiens 64-67 11939791-2 2002 The interaction of the carboxyl-terminal lysine residues of the p11 subunit of AIIt with the lysine-binding kringle domains of plasminogen is believed to play a key role in plasminogen binding and stimulation of the tPA-catalyzed cleavage of plasminogen to plasmin. Tetradecanoylphorbol Acetate 216-219 S100 calcium binding protein A10 Homo sapiens 64-67 11939791-7 2002 Treatment of AIIt with carboxypeptidase resulted in loss of both carboxyl-terminal lysine residues from the p11 subunit, which correlated with a decrease in the k(cat) and an increase in the K(m) for plasminogen activation. Lysine 83-89 S100 calcium binding protein A10 Homo sapiens 108-111 11802744-8 2002 ONOO(-) also caused the formation of dimers between p36 and p11 subunits which were stable in the presence of heating, SDS, and beta-mercaptoethanol. onoo 0-4 S100 calcium binding protein A10 Homo sapiens 60-63 11796712-4 2002 It is shown that the p10 protein exhibits all characteristics of an actively transported molecule in digitonin-permeabilized cells. Digitonin 101-110 S100 calcium binding protein A10 Homo sapiens 21-24 11802744-8 2002 ONOO(-) also caused the formation of dimers between p36 and p11 subunits which were stable in the presence of heating, SDS, and beta-mercaptoethanol. Sodium Dodecyl Sulfate 119-122 S100 calcium binding protein A10 Homo sapiens 60-63 11802744-8 2002 ONOO(-) also caused the formation of dimers between p36 and p11 subunits which were stable in the presence of heating, SDS, and beta-mercaptoethanol. Mercaptoethanol 128-148 S100 calcium binding protein A10 Homo sapiens 60-63 11319229-3 2001 Furthermore, the C-terminal lysine residues of its p11 subunit play an essential role in the inhibition of fibrin clot lysis by AIIt. Lysine 28-34 S100 calcium binding protein A10 Homo sapiens 51-54 11535243-5 2001 Further, we show that hGSTs A2-2, P1-1, M1-1, T1-1 and T2-2 appear to have low activity towards N-acetoxy-PhIP, and that hGSTs A4-4, M2-2, M4-4 and Z1-1 appear to have no activity towards N-acetoxy-PhIP. 2-(acetoxyamino)-1-methyl-6-phenylimidazo(4,5-b)pyridine 188-202 S100 calcium binding protein A10 Homo sapiens 34-38 11535243-5 2001 Further, we show that hGSTs A2-2, P1-1, M1-1, T1-1 and T2-2 appear to have low activity towards N-acetoxy-PhIP, and that hGSTs A4-4, M2-2, M4-4 and Z1-1 appear to have no activity towards N-acetoxy-PhIP. 2-(acetoxyamino)-1-methyl-6-phenylimidazo(4,5-b)pyridine 96-110 S100 calcium binding protein A10 Homo sapiens 34-38 11526307-1 2001 The structure of a decagonal Al72Ni20Co8 quasicrystal with space group P10(5)/mmc has been determined on the basis of a single-crystal X-ray data set using the five-dimensional description. al72ni20co8 29-40 S100 calcium binding protein A10 Homo sapiens 71-74 11368548-0 2001 Role of glutathione S-transferases A1-1, M1-1, and P1-1 in the detoxification of 2-phenylpropenal, a reactive felbamate metabolite. hydratropic aldehyde 81-97 S100 calcium binding protein A10 Homo sapiens 51-55 11368548-0 2001 Role of glutathione S-transferases A1-1, M1-1, and P1-1 in the detoxification of 2-phenylpropenal, a reactive felbamate metabolite. Felbamate 110-119 S100 calcium binding protein A10 Homo sapiens 51-55 11294649-2 2001 The four cysteines (Cys 14, Cys 47, Cys 101, and Cys 169 in the primary sequence) in hGST P1-1 are susceptible to electrophilic attack and/or oxidative damage leading to loss of enzymatic activity. Cysteine 20-23 S100 calcium binding protein A10 Homo sapiens 90-94 11294649-2 2001 The four cysteines (Cys 14, Cys 47, Cys 101, and Cys 169 in the primary sequence) in hGST P1-1 are susceptible to electrophilic attack and/or oxidative damage leading to loss of enzymatic activity. Cysteine 28-31 S100 calcium binding protein A10 Homo sapiens 90-94 11294649-0 2001 Structural and functional consequences of inactivation of human glutathione S-transferase P1-1 mediated by the catechol metabolite of equine estrogens, 4-hydroxyequilenin. catechol 111-119 S100 calcium binding protein A10 Homo sapiens 90-94 11294649-2 2001 The four cysteines (Cys 14, Cys 47, Cys 101, and Cys 169 in the primary sequence) in hGST P1-1 are susceptible to electrophilic attack and/or oxidative damage leading to loss of enzymatic activity. Cysteine 28-31 S100 calcium binding protein A10 Homo sapiens 90-94 11294649-2 2001 The four cysteines (Cys 14, Cys 47, Cys 101, and Cys 169 in the primary sequence) in hGST P1-1 are susceptible to electrophilic attack and/or oxidative damage leading to loss of enzymatic activity. Cysteine 28-31 S100 calcium binding protein A10 Homo sapiens 90-94 11294649-0 2001 Structural and functional consequences of inactivation of human glutathione S-transferase P1-1 mediated by the catechol metabolite of equine estrogens, 4-hydroxyequilenin. 4-hydroxy-equilenin 152-170 S100 calcium binding protein A10 Homo sapiens 90-94 11495355-3 2001 In the present study we describe the affi-gel blue-nonbinding phosphatases which were separated into seven different phosphatase activities, designated P5-P11 by poly-(L-lysine)-agarose and aminohexyl Sepharose 4B chromatographies. poly-(l-lysine)-agarose 162-185 S100 calcium binding protein A10 Homo sapiens 155-158 11294649-2 2001 The four cysteines (Cys 14, Cys 47, Cys 101, and Cys 169 in the primary sequence) in hGST P1-1 are susceptible to electrophilic attack and/or oxidative damage leading to loss of enzymatic activity. Cysteine 9-18 S100 calcium binding protein A10 Homo sapiens 90-94 11495355-3 2001 In the present study we describe the affi-gel blue-nonbinding phosphatases which were separated into seven different phosphatase activities, designated P5-P11 by poly-(L-lysine)-agarose and aminohexyl Sepharose 4B chromatographies. Sepharose 201-210 S100 calcium binding protein A10 Homo sapiens 155-158 11123923-0 2000 Valine 10 may act as a driver for product release from the active site of human glutathione transferase P1-1. Valine 0-6 S100 calcium binding protein A10 Homo sapiens 104-108 11123923-1 2000 We have probed the electrophilic binding site (H-site) of human glutathione transferase P1-1 through mutagenesis of two valines, Val 10 and Val 35, into glycine and alanine, respectively. Valine 120-127 S100 calcium binding protein A10 Homo sapiens 88-92 11123923-1 2000 We have probed the electrophilic binding site (H-site) of human glutathione transferase P1-1 through mutagenesis of two valines, Val 10 and Val 35, into glycine and alanine, respectively. Alanine 165-172 S100 calcium binding protein A10 Homo sapiens 88-92 11038179-2 2000 We constructed a point mutant of p10, D23A, that exhibited unexpected behavior both in digitonin-permeabilized and microinjected mammalian cells. Digitonin 87-96 S100 calcium binding protein A10 Homo sapiens 33-36 11076800-0 2000 Retinoic acid reduces p11 protein levels in bronchial epithelial cells by a posttranslational mechanism. Tretinoin 0-13 S100 calcium binding protein A10 Homo sapiens 22-25 11076800-1 2000 p11 is a member of the S100 family of proteins, is the cellular ligand of annexin II, and interacts with the carboxyl region of 85-kDa cytosolic phospholipase A(2) (cPLA(2)), inhibiting cPLA(2) activity and arachidonic acid (AA) release. Arachidonic Acid 207-223 S100 calcium binding protein A10 Homo sapiens 0-3 11076800-3 2000 The addition of 10(-6) M RA resulted in reduced p11 protein levels at 4 days, with the greatest effect observed on days 6 and 7. Tretinoin 25-27 S100 calcium binding protein A10 Homo sapiens 48-51 11076800-7 2000 Treatment with RA reduced p11 levels in control cells and in cells transfected with a p11 expression vector, suggesting a posttranslational mechanism. Tretinoin 15-17 S100 calcium binding protein A10 Homo sapiens 26-29 11076800-7 2000 Treatment with RA reduced p11 levels in control cells and in cells transfected with a p11 expression vector, suggesting a posttranslational mechanism. Tretinoin 15-17 S100 calcium binding protein A10 Homo sapiens 86-89 11076800-8 2000 Lactacystin (10(-6) M), an inhibitor of the human 26S proteasome, blocked the decrease in p11 observed with RA treatment. lactacystin 0-11 S100 calcium binding protein A10 Homo sapiens 90-93 11076800-8 2000 Lactacystin (10(-6) M), an inhibitor of the human 26S proteasome, blocked the decrease in p11 observed with RA treatment. Tretinoin 108-110 S100 calcium binding protein A10 Homo sapiens 90-93 10858627-3 2000 Another member of the S100 family (S100A10) was found to modulate phospholipid turnover by inhibiting the activity of enzyme phospholipase A2 (PLA2). Phospholipids 66-78 S100 calcium binding protein A10 Homo sapiens 35-42 10852453-11 2000 Caloric deprivation in aging men also disproportionately elevated the mesor of 24-h rhythmic cortisol release (P = 10(-7)) and elicited a greater increment in the mean day-night variation in cortisol secretory-burst mass (P < 0.01 vs. young controls). Hydrocortisone 93-101 S100 calcium binding protein A10 Homo sapiens 111-117 10768774-6 2000 Sequence similarity between P1-1 and BPV 5 DNA at the nucleotide and amino acid level was limited to a stretch of 58 nucleotides which includes an oligopurine/pyrimidine tract. oligopurine 147-158 S100 calcium binding protein A10 Homo sapiens 28-32 10725419-5 2000 Immunoaffinity chromatography demonstrated the presence of high-salt stable complexes of p10 containing the p24 and p38/p39 proteins in extracts of BDV-infected cells. Salts 64-68 S100 calcium binding protein A10 Homo sapiens 89-92 10768774-6 2000 Sequence similarity between P1-1 and BPV 5 DNA at the nucleotide and amino acid level was limited to a stretch of 58 nucleotides which includes an oligopurine/pyrimidine tract. pyrimidine 159-169 S100 calcium binding protein A10 Homo sapiens 28-32 10648784-8 2000 The role played by Mg(2+)ions in formation of the P1.1 structure is also discussed. magnesium ion 19-25 S100 calcium binding protein A10 Homo sapiens 50-54 10657731-6 1999 This persisted throughout juvenile development (P10, P17) and was present also in the adult male (P75), but in the peripubertal period the response to bicuculline was first lost (P25) and then reversed to an inhibition (P40), suggesting a transient switch to an apparent stimulatory GABAergic tone on SRIH release. Bicuculline 151-162 S100 calcium binding protein A10 Homo sapiens 48-51