PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
24723223-10	2014	Silencing of Dicer induces sensitivity to gefitinib in NSCLC cells through the downregulation of miR-30b/c and miR-221/222 to increase the protein level of caspase-3, resulting in an increase in gefitinib-induced apoptosis.	Gefitinib	42-51	microRNA 30b	Homo sapiens	97-104
24723223-10	2014	Silencing of Dicer induces sensitivity to gefitinib in NSCLC cells through the downregulation of miR-30b/c and miR-221/222 to increase the protein level of caspase-3, resulting in an increase in gefitinib-induced apoptosis.	Gefitinib	195-204	microRNA 30b	Homo sapiens	97-104
24913034-12	2014	Overexpression of miR-30b-5p inhibited cell migration.	CHEMBL3740941	26-28	microRNA 30b	Homo sapiens	18-25
34876159-8	2021	As the results shown, miR-30b-5p was negatively correlated with CD4 + T cell counts (r = - 0.41, P = 0.027) and marginally positively correlated with fasting plasma glucose in COVID-19 patients (r = 0.37, P = 0.052).	Glucose	165-172	microRNA 30b	Homo sapiens	22-29
24286402-3	2013	It has been recently reported that epidermal growth factor receptor (EGFR) and hepatocyte growth factor receptor (MET) tyrosine kinase can regulate expression of specific microRNAs including miR-30b, miR-30c, miR-221, miR-222, miR-103 and miR-203, and induce tumorigenesis and gefitinib resistance in lung cancers.	Gefitinib	277-286	microRNA 30b	Homo sapiens	191-198
24286402-5	2013	METHODS: We have therefore retrospectively examined expression of miR-30b miR-30c in 41 formalin fixed paraffin embedded tissue samples from NSCLC patients when TKIs were used as first line therapy.	Formaldehyde	88-96	microRNA 30b	Homo sapiens	66-73
24286402-5	2013	METHODS: We have therefore retrospectively examined expression of miR-30b miR-30c in 41 formalin fixed paraffin embedded tissue samples from NSCLC patients when TKIs were used as first line therapy.	Paraffin	103-111	microRNA 30b	Homo sapiens	66-73
23934683-5	2013	Twelve miRNA showed altered expression after Se depletion: miR-625, miR-492, miR-373*, miR-22, miR-532-5p, miR-106b, miR-30b, miR-185, miR-203, miR1308, miR-28-5p, miR-10b.	Selenium	45-47	microRNA 30b	Homo sapiens	117-124
23893664-10	2013	Moreover, the expression of miR-30b was down-regulated in bleomycin-treated sclerotic skin and in affected skin in SSc patients.	Bleomycin	58-67	microRNA 30b	Homo sapiens	28-35
22880027-8	2012	Here, we demonstrated that a sublethal dose of H(2)O(2) (200 microM) up-regulated the expression of miR-30b, a member of the miR-30 family, which inhibited the expression of endogenous catalase both at the transcript and protein levels.	Hydrogen Peroxide	47-55	microRNA 30b	Homo sapiens	100-107
33779882-0	2021	miR-30b-5p inhibits cancer progression and enhances cisplatin sensitivity in lung cancer through targeting LRP8.	Cisplatin	52-61	microRNA 30b	Homo sapiens	0-7
33779882-8	2021	In addition, miR-30b-5p was lowly expressed in A549/DDP (a cisplatin drug resistant cell line) as compared with A549 cells, and miR-30b-5p increased A549/DDP cell sensitivity to DDP.	Cisplatin	59-68	microRNA 30b	Homo sapiens	13-20
33779882-8	2021	In addition, miR-30b-5p was lowly expressed in A549/DDP (a cisplatin drug resistant cell line) as compared with A549 cells, and miR-30b-5p increased A549/DDP cell sensitivity to DDP.	Cisplatin	59-68	microRNA 30b	Homo sapiens	128-135
33779882-8	2021	In addition, miR-30b-5p was lowly expressed in A549/DDP (a cisplatin drug resistant cell line) as compared with A549 cells, and miR-30b-5p increased A549/DDP cell sensitivity to DDP.	Cisplatin	52-55	microRNA 30b	Homo sapiens	13-20
35100079-7	2022	Downregulating miR-30b-5p enhanced the expression of OCN, RUNX2, and ALP, and promoted calcium deposition.	Calcium	87-94	microRNA 30b	Homo sapiens	15-22
35401922-12	2022	Finally, we found that miR-30b is able to increase the cellular viability under the H/R condition, partially mimicking the protective effect of propofol which suppressed autophagy via enhancing miR-30b and targeting Beclin-1.	Propofol	144-152	microRNA 30b	Homo sapiens	194-201
35401922-13	2022	Therefore, we concluded that propofol upregulates miR-30b to repress excessive autophagy via targeting Beclin-1 under H/R condition.	Propofol	29-37	microRNA 30b	Homo sapiens	50-57
35401922-17	2022	The name of the trial register: Propofol Upregulates MicroRNA-30b to Repress Beclin-1 and Inhibits Excessive Autophagy and Apoptosis.	Propofol	32-40	microRNA 30b	Homo sapiens	53-65
32299444-5	2020	The effect of miR-30b-5p on the lipid deposition in Huh-7 cells was tested by oil red O staining and TG concentrations measurement.	oil red O	78-87	microRNA 30b	Homo sapiens	14-21
33667194-5	2021	RESULTS: During the 12 months of the study, circulating miR-30b expression increased 2.4 +- 2.5 (SD) fold (p=0.008) in all boys, but this change did not correlate with corresponding changes in LH, testosterone, inhibin B, FSH, or testicular volume (p=0.25-0.96).	Testosterone	197-209	microRNA 30b	Homo sapiens	56-63
33667194-6	2021	Lz-induced activation of the hypothalamic-pituitary-gonadal (HPG) axis was associated with more variable miR-30b responses at 3 months (P<0.05), whereas those treated with T exhibited significant changes in relative miR-30b levels in the course the study (p<0.01-0.05).	lz	0-2	microRNA 30b	Homo sapiens	105-112
33667194-6	2021	Lz-induced activation of the hypothalamic-pituitary-gonadal (HPG) axis was associated with more variable miR-30b responses at 3 months (P<0.05), whereas those treated with T exhibited significant changes in relative miR-30b levels in the course the study (p<0.01-0.05).	lz	0-2	microRNA 30b	Homo sapiens	216-223
33995095-7	2021	PA also inhibited the nuclear transfection of miR-30b-5p induced by H. pylori, thereby enhancing transcription factor EB function and increasing lysosome activity.	patchouli alcohol	0-2	microRNA 30b	Homo sapiens	46-53
33995095-8	2021	The finding of strongly invasive intracellular H. pylori has great implications for clinical treatment, and PA can act against invasive H. pylori based on the improvement of miR-30b/c mediated xenophagy.	patchouli alcohol	108-110	microRNA 30b	Homo sapiens	174-181
33477007-0	2021	Circulating miR-30b-5p levels in plasma as a novel potential biomarker for early detection of breast cancer.	CHEMBL3740941	20-22	microRNA 30b	Homo sapiens	12-19
32977360-7	2020	GTP-RhoA and ROCK expression were down-regulated by miR-30b.	Guanosine Triphosphate	0-3	microRNA 30b	Homo sapiens	52-59
32977360-8	2020	Neurite outgrowth that inhibited by sema3A and the miR-30b antagomir was increased by Y-27632.	Y 27632	86-93	microRNA 30b	Homo sapiens	51-58
32690599-11	2020	Downregulated miR-30b-5p exerted the opposite effect.	CHEMBL3740941	22-24	microRNA 30b	Homo sapiens	14-21
32112903-8	2020	Further in vivo experiments demonstrated that miR-30b-5p overexpression inhibited CRLM, but Rap1b rescue attenuated the inhibitory effect of miR-30b-5p.	CHEMBL3740941	54-56	microRNA 30b	Homo sapiens	46-53
35401922-0	2022	Propofol Upregulates MicroRNA-30b to Inhibit Excessive Autophagy and Apoptosis and Attenuates Ischemia/Reperfusion Injury In Vitro and in Patients.	Propofol	0-8	microRNA 30b	Homo sapiens	21-33
35401922-3	2022	Here, we found that one of these microRNAs, microRNA-30b (miR-30b), in human umbilical vein endothelial cells (HUVECs) was downregulated by H/R treatment but significantly upregulated by 100 M propofol after H/R treatment.	Propofol	193-201	microRNA 30b	Homo sapiens	44-56
35401922-3	2022	Here, we found that one of these microRNAs, microRNA-30b (miR-30b), in human umbilical vein endothelial cells (HUVECs) was downregulated by H/R treatment but significantly upregulated by 100 M propofol after H/R treatment.	Propofol	193-201	microRNA 30b	Homo sapiens	58-65
32299444-5	2020	The effect of miR-30b-5p on the lipid deposition in Huh-7 cells was tested by oil red O staining and TG concentrations measurement.	Thioguanine	101-103	microRNA 30b	Homo sapiens	14-21
32154657-2	2020	MATERIALS AND METHODS: We used 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPP(+)) as a tool for constructing the PD cell model, using miR-30b mimics or inhibitors to manipulate miR-30b level for an experimental model of acquisition.	mangion-purified polysaccharide (Candida albicans)	77-80	microRNA 30b	Homo sapiens	137-144
32299444-9	2020	Overexpressing miR-30b-5p in Huh-7 cells decreased the number and size of lipid droplets and intracellular TG concentrations in Huh-7 cells.	Thioguanine	107-109	microRNA 30b	Homo sapiens	15-22
31839047-0	2019	[MiR-30b Regulates the Cisplatin-Resistance of Human NK/T Cell Lypnphoma Cell Lines SNK-6 and YTS by Targeting the CCL22].	Cisplatin	23-32	microRNA 30b	Homo sapiens	1-8
32154657-2	2020	MATERIALS AND METHODS: We used 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPP(+)) as a tool for constructing the PD cell model, using miR-30b mimics or inhibitors to manipulate miR-30b level for an experimental model of acquisition.	mangion-purified polysaccharide (Candida albicans)	77-80	microRNA 30b	Homo sapiens	180-187
32143184-5	2020	In this context, the ectopic recovery of miR-30b and miR-30c led to significant changes in genes related to FA metabolism, consistent reduction of ceramides, higher mitochondrial activity, and enabled beta-oxidation, redirecting FA metabolism from energy storage to expenditure.	Ceramides	147-156	microRNA 30b	Homo sapiens	41-48
31926547-7	2020	Inhibition of the Hippo pathway transcriptional co-activator YAP suppresses the resistance to platinum-based therapy induced by either low MYPT1 expression or miR-30b overexpression, both in vitro and in vivo.	Platinum	94-102	microRNA 30b	Homo sapiens	159-166
31839047-1	2019	OBJECTIVE: To explore the effect and mechanism of miR-30b on cisplatin-resistance of human NK/T cell lymphoma lines SNK-6 and YTS cells.	Cisplatin	61-70	microRNA 30b	Homo sapiens	50-57
31839047-7	2019	MiR-30b mimics decreased the cell activity (P<0.05), down-regulated the cisplatin-resistance (P<0.05), and increased cell apoptosis and caspase-3 activity (P<0.05).	Cisplatin	72-81	microRNA 30b	Homo sapiens	0-7
31839047-12	2019	CONCLUSION: MiR-30b inhibits cisplatin-resistance of human NK/TCL SNK-6 and YTS cells by targeting CCL22.	Cisplatin	29-38	microRNA 30b	Homo sapiens	12-19
31054938-11	2019	These data suggest that miR-30b contributes to oxaliplatin-induced chronic neuropathic pain through Nav1.6 downregulation and could be a novel therapeutic target for the treatment of oxaliplatin-induced neuropathic pain as a side effect of chemotherapy in cancer patients.	Oxaliplatin	47-58	microRNA 30b	Homo sapiens	24-31
31447008-0	2019	Circulating miR-30b and miR-30c predict erlotinib response in EGFR-mutated non-small cell lung cancer patients.	Erlotinib Hydrochloride	40-49	microRNA 30b	Homo sapiens	12-19
31447008-1	2019	OBJECTIVES: MiR-30b, miR-30c, miR-221 and miR-222 are known to induce gefitinib resistance in lung cancer cell lines with activation of mutations in the epidermal growth factor receptor (EGFR).	Gefitinib	70-79	microRNA 30b	Homo sapiens	12-19
30701530-9	2019	Knockdown of miR-30b reduced MMP and autophagy, elevated VC, and suppressed the presence of rapamycin (an inhibitor of the mTOR signaling pathway).	Sirolimus	92-101	microRNA 30b	Homo sapiens	13-20
31054938-11	2019	These data suggest that miR-30b contributes to oxaliplatin-induced chronic neuropathic pain through Nav1.6 downregulation and could be a novel therapeutic target for the treatment of oxaliplatin-induced neuropathic pain as a side effect of chemotherapy in cancer patients.	Oxaliplatin	183-194	microRNA 30b	Homo sapiens	24-31
31239715-10	2019	Function analysis demonstrated that FLJ33360 can act as a molecular sponge of miR-30b-3p to regulate the expression of target genes that are mainly involved in positive regulation of smooth muscle cell migration, the unsaturated fatty acid metabolic process, and positive regulation of the epithelial to mesenchymal transition.	Fatty Acids, Unsaturated	217-239	microRNA 30b	Homo sapiens	78-85
31093946-0	2019	Involvement of miR-30b in kynurenine-mediated lysyl oxidase expression.	Kynurenine	26-36	microRNA 30b	Homo sapiens	15-22
31093946-8	2019	Most importantly, not only was Kyn-induced increase of LOX mRNA significantly attenuated on miR-30b mimics treatment, but also Kyn-mediated the upregulation of the mRNA, and secreted levels of LOX were distinctly strengthened on miR-30b inhibitor treatment.	Kynurenine	31-34	microRNA 30b	Homo sapiens	92-99
31093946-8	2019	Most importantly, not only was Kyn-induced increase of LOX mRNA significantly attenuated on miR-30b mimics treatment, but also Kyn-mediated the upregulation of the mRNA, and secreted levels of LOX were distinctly strengthened on miR-30b inhibitor treatment.	Kynurenine	31-34	microRNA 30b	Homo sapiens	229-236
30154732-12	2018	Furthermore, bioinformatic analyses showed that some potential target genes of miR-144-5p and miR-30b-5p are involved in the erythroid- hypoxia-, and nitric oxide (NO)-related signaling pathways in response to hypoxia.	Nitric Oxide	150-162	microRNA 30b	Homo sapiens	94-101
30365113-0	2019	LncRNA MALAT1 potentiates autophagy-associated cisplatin resistance by regulating the microRNA-30b/autophagy-related gene 5 axis in gastric cancer.	Cisplatin	47-56	microRNA 30b	Homo sapiens	86-98
30365113-11	2019	Moreover, miR-30b abolished MALAT1-induced CDDP resistance by inhibiting autophagy in AGS/CDDP and HGC-27/CDDP cells.	Cisplatin	43-47	microRNA 30b	Homo sapiens	10-17
30365113-13	2019	miR-30b weakened resistance to CDDP by inhibiting autophagy in AGS/CDDP and HGC-27/CDDP cells, while this effect was abrogated by increased ATG5 expression.	Cisplatin	31-35	microRNA 30b	Homo sapiens	0-7
30365113-13	2019	miR-30b weakened resistance to CDDP by inhibiting autophagy in AGS/CDDP and HGC-27/CDDP cells, while this effect was abrogated by increased ATG5 expression.	Cisplatin	67-71	microRNA 30b	Homo sapiens	0-7
28905195-0	2017	Experimental evidences for miR-30b as a negative regulator of FOXO3 upregulated by kynurenine.	Kynurenine	83-93	microRNA 30b	Homo sapiens	27-34
30108445-7	2018	miR-30b-5p expression was significantly lower in gliomas than the normal brain tissues.	CHEMBL3740941	8-10	microRNA 30b	Homo sapiens	0-7
28905195-7	2017	More importantly, miR-30b-induced suppression of FOXO3 protein was significantly attenuated on Kyn treatment, which demonstrated that Kyn-mediated increase of FOXO3 depended at least partly on miR-30b.	Kynurenine	95-98	microRNA 30b	Homo sapiens	18-25
28905195-7	2017	More importantly, miR-30b-induced suppression of FOXO3 protein was significantly attenuated on Kyn treatment, which demonstrated that Kyn-mediated increase of FOXO3 depended at least partly on miR-30b.	Kynurenine	95-98	microRNA 30b	Homo sapiens	193-200
28905195-7	2017	More importantly, miR-30b-induced suppression of FOXO3 protein was significantly attenuated on Kyn treatment, which demonstrated that Kyn-mediated increase of FOXO3 depended at least partly on miR-30b.	Kynurenine	134-137	microRNA 30b	Homo sapiens	18-25
28905195-7	2017	More importantly, miR-30b-induced suppression of FOXO3 protein was significantly attenuated on Kyn treatment, which demonstrated that Kyn-mediated increase of FOXO3 depended at least partly on miR-30b.	Kynurenine	134-137	microRNA 30b	Homo sapiens	193-200
28905195-8	2017	In addition, Kyn-mediated upregulation of migration, a method of measuring cancer metastasis, was markedly decreased on miR-30b treatment, in vitro, which was altered in some degree via regulating FOXO3.	Kynurenine	13-16	microRNA 30b	Homo sapiens	120-127
28119530-13	2017	In partial agreement, PA (but not HG) led to decreased miR-139-5p, miR-30b-5p, miR-422a and miR-146a in vitro, in parallel with increased lipogenesis and FA transport, decreased glucose metabolism and diminished FA oxidation.	Palmitic Acid	22-24	microRNA 30b	Homo sapiens	67-74
27894814-0	2017	Tanshinone IIA induced cell death via miR30b-p53-PTPN11/SHP2 signaling pathway in human hepatocellular carcinoma cells.	tanshinone	0-10	microRNA 30b	Homo sapiens	38-44
27894814-12	2017	This study confirmed that Tanshinone IIA may induce hepatoma cell death through the miR30b-p53- PTPN11/SHP2 pathway.	tanshinone	26-40	microRNA 30b	Homo sapiens	84-90
27419135-9	2016	As miR-30b, miR-133a, and miR-143 are negatively regulated by Pi and restored by Mg(2+) with a congruent modulation of their known targets Runx2, Smad1, and Osterix, our results provide a potential mechanistic explanation of the observed upregulation of these master switches of osteogenesis during the course of VC.	magnesium ion	81-87	microRNA 30b	Homo sapiens	3-10
26263983-9	2015	In addition, overexpression of miR-30b can improve the Hcy-induced apoptosis in HCAECs by downregulating caspase-3 expression.	Homocysteine	55-58	microRNA 30b	Homo sapiens	31-38
26263983-10	2015	Therefore, miR-30b may play an important role in Hcy-induced apoptosis in endothelial cells.	Homocysteine	49-52	microRNA 30b	Homo sapiens	11-18
26590946-2	2016	Previous studies have revealed that L-kynurenine (L-Kyn) level was changed significantly in patient with cancer and that miR-30b play different role in tumor cells and immune cells.	Kynurenine	36-48	microRNA 30b	Homo sapiens	121-128
26590946-2	2016	Previous studies have revealed that L-kynurenine (L-Kyn) level was changed significantly in patient with cancer and that miR-30b play different role in tumor cells and immune cells.	Kynurenine	50-55	microRNA 30b	Homo sapiens	121-128
26590946-3	2016	Moreover, it has been also conformed that miR-30b involved in the process of L-Kyn-mediated suppression of humoral immune responses induced by lipopolysaccharide (LPS) in human normal B cells separated from volunteers" peripheral blood.	Kynurenine	77-82	microRNA 30b	Homo sapiens	42-49
26263983-8	2015	In this study, we constructed the model of homocysteine-induced apoptosis in human coronary artery endothelial cells (HCAECs) and found miR-30b was significantly down-regulated by 1 mmol/L Hcy.	Homocysteine	43-55	microRNA 30b	Homo sapiens	136-143