PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 34881243-7 2021 Mechanistically, Wnt7b impacts the glucose metabolic process and AKT activation during osteoclastogenesis. Glucose 35-42 Wnt family member 7B Homo sapiens 17-22 34999254-8 2022 miR-34a-5p directly targeted WNT7B and inhibited WNT7B expression. mir-34a-5p 0-10 Wnt family member 7B Homo sapiens 29-34 34999254-8 2022 miR-34a-5p directly targeted WNT7B and inhibited WNT7B expression. mir-34a-5p 0-10 Wnt family member 7B Homo sapiens 49-54 34999254-9 2022 Under PDT treatment, WNT7B knockdown inhibited the Wnt signaling and cell viability, and promoted cell apoptosis, while miR-34a-5p suppression showed the opposite trends; WNT7B knockdown partially attenuated miR-34a-5p inhibition effects on PDT-treated cholangiocarcinoma cells. mir-34a-5p 120-130 Wnt family member 7B Homo sapiens 171-176 34999254-9 2022 Under PDT treatment, WNT7B knockdown inhibited the Wnt signaling and cell viability, and promoted cell apoptosis, while miR-34a-5p suppression showed the opposite trends; WNT7B knockdown partially attenuated miR-34a-5p inhibition effects on PDT-treated cholangiocarcinoma cells. mir-34a 208-215 Wnt family member 7B Homo sapiens 171-176 34999254-9 2022 Under PDT treatment, WNT7B knockdown inhibited the Wnt signaling and cell viability, and promoted cell apoptosis, while miR-34a-5p suppression showed the opposite trends; WNT7B knockdown partially attenuated miR-34a-5p inhibition effects on PDT-treated cholangiocarcinoma cells. CHEMBL3740941 216-218 Wnt family member 7B Homo sapiens 21-26 34999254-9 2022 Under PDT treatment, WNT7B knockdown inhibited the Wnt signaling and cell viability, and promoted cell apoptosis, while miR-34a-5p suppression showed the opposite trends; WNT7B knockdown partially attenuated miR-34a-5p inhibition effects on PDT-treated cholangiocarcinoma cells. CHEMBL3740941 216-218 Wnt family member 7B Homo sapiens 171-176 33934523-2 2021 Fzd7/Wnt7b knockdown in Capan-2 and Panc-1 cells reduced the proliferative capacity of pancreatic cancer stem cells (PCSCs), reduced drug resistance, decreased the percentage of CD24+ CD44+ subset of cells and the levels of ABCG2, inhibited cell-sphere formation, and reduced gemcitabine (GEM) resistance. gemcitabine 276-287 Wnt family member 7B Homo sapiens 5-10 33934523-2 2021 Fzd7/Wnt7b knockdown in Capan-2 and Panc-1 cells reduced the proliferative capacity of pancreatic cancer stem cells (PCSCs), reduced drug resistance, decreased the percentage of CD24+ CD44+ subset of cells and the levels of ABCG2, inhibited cell-sphere formation, and reduced gemcitabine (GEM) resistance. gemcitabine 289-292 Wnt family member 7B Homo sapiens 5-10 32577947-14 2020 MiR-30c-5p targeted Wnt7b to inhibit ox-LDL-induced Wnt7b/beta-catenin activation, EndMT, inflammatory response, and apoptosis in HUVEC cells. mir-30c-5p 0-10 Wnt family member 7B Homo sapiens 20-25 32577947-14 2020 MiR-30c-5p targeted Wnt7b to inhibit ox-LDL-induced Wnt7b/beta-catenin activation, EndMT, inflammatory response, and apoptosis in HUVEC cells. mir-30c-5p 0-10 Wnt family member 7B Homo sapiens 52-57 28462819-4 2017 Here, we identified that WNT7B and WNT8B secreted from hepatocytes and cholangiocytes play important roles in achieving perivenous zone-specific characteristics, such as the enhancement of glutamine secretion, citric acid cycle, cytochrome P450 (CYP) 1A2 metabolism, and CYP1A2 induction capacities. Citric Acid 210-221 Wnt family member 7B Homo sapiens 25-30 32761137-4 2020 Results: Two SNPs-namely, rs12144790 in RSPO1 (allele T, P = 0.0066, beta = 0.062) and rs10453441 in WNT7B (allele A, P = 8.03 x 10-6, beta = 0.103)-were significantly associated with AL. Aluminum 184-186 Wnt family member 7B Homo sapiens 101-106 32761137-9 2020 Conclusions: This study revealed that the RSPO1 SNP rs12144790 was associated with AL, whereas WNT7B rs10453441 was associated with AL, CC, and CCT in children. Aluminum 132-134 Wnt family member 7B Homo sapiens 95-100 32761137-9 2020 Conclusions: This study revealed that the RSPO1 SNP rs12144790 was associated with AL, whereas WNT7B rs10453441 was associated with AL, CC, and CCT in children. cct 144-147 Wnt family member 7B Homo sapiens 95-100 32711579-14 2020 Furthermore, miR-503-3p high-expression reduced the activity of the W-beta pathway, as indicated by lowering expression of Wnt2 and Wnt7b, inactive beta-catenin in miR-503-3p-treated hASCs. mir-503-3p 13-23 Wnt family member 7B Homo sapiens 132-137 32711579-14 2020 Furthermore, miR-503-3p high-expression reduced the activity of the W-beta pathway, as indicated by lowering expression of Wnt2 and Wnt7b, inactive beta-catenin in miR-503-3p-treated hASCs. mir-503-3p 164-174 Wnt family member 7B Homo sapiens 132-137 32294447-5 2020 LiCl and a GSK3beta inhibitor, two WNT-signaling agonists, robustly rescue the dendritic spines and the synaptic and axonal defects, suggesting that this could have relevance for therapeutic approaches in some forms of ASD. Lithium Chloride 0-4 Wnt family member 7B Homo sapiens 35-38 31680323-11 2020 Rescue experiments suggested that downregulated WNT7B rescued miR-199a-5p inhibitor-mediated repression on OS progression, but the treatment of LiCl counteracted the effect of WNT7B downregulation. Lithium Chloride 144-148 Wnt family member 7B Homo sapiens 176-181 29906532-0 2018 Combination with TMZ and miR-505 inhibits the development of glioblastoma by regulating the WNT7B/Wnt/beta-catenin signaling pathway. Temozolomide 17-20 Wnt family member 7B Homo sapiens 92-97 28462819-4 2017 Here, we identified that WNT7B and WNT8B secreted from hepatocytes and cholangiocytes play important roles in achieving perivenous zone-specific characteristics, such as the enhancement of glutamine secretion, citric acid cycle, cytochrome P450 (CYP) 1A2 metabolism, and CYP1A2 induction capacities. Glutamine 189-198 Wnt family member 7B Homo sapiens 25-30 31601147-0 2019 miR-342-5p inhibits osteosarcoma cell growth, migration, invasion, and sensitivity to Doxorubicin through targeting Wnt7b. Doxorubicin 86-97 Wnt family member 7B Homo sapiens 116-121 30266078-12 2018 Therefore, FOS, AHR, JUN, CYP1A1, EGR1, FOSL1, and WNT7B might be targets of quercetin in gastric cancer. Quercetin 77-86 Wnt family member 7B Homo sapiens 51-56 29268145-2 2018 DESIGN: The effect of recombinant human WNT7B (rhWNT7B) on the proliferation and migration of HDPCs was evaluated by 5-ethynyl-2"-deoxyuridine (EdU), immunofluorescence staining of Ki67, flow cytometry and scratch assay; the differentiation of HDPCs was measured by alkaline phosphatase (ALP) staining, alizarin red staining, ALP activity, qPCR and western blot. 5-ethynyl-2'-deoxyuridine 117-142 Wnt family member 7B Homo sapiens 40-45 29268145-2 2018 DESIGN: The effect of recombinant human WNT7B (rhWNT7B) on the proliferation and migration of HDPCs was evaluated by 5-ethynyl-2"-deoxyuridine (EdU), immunofluorescence staining of Ki67, flow cytometry and scratch assay; the differentiation of HDPCs was measured by alkaline phosphatase (ALP) staining, alizarin red staining, ALP activity, qPCR and western blot. ethylene diurea 144-147 Wnt family member 7B Homo sapiens 40-45 29268145-2 2018 DESIGN: The effect of recombinant human WNT7B (rhWNT7B) on the proliferation and migration of HDPCs was evaluated by 5-ethynyl-2"-deoxyuridine (EdU), immunofluorescence staining of Ki67, flow cytometry and scratch assay; the differentiation of HDPCs was measured by alkaline phosphatase (ALP) staining, alizarin red staining, ALP activity, qPCR and western blot. alizarin 303-315 Wnt family member 7B Homo sapiens 40-45 29268145-8 2018 XAV939 and SP600125 can partly offset the effect of the WNT7B-induced differentiation of HDPCs. pyrazolanthrone 11-19 Wnt family member 7B Homo sapiens 56-61 27660676-9 2016 Wnt ligands found to be elevated in human CCA were also upregulated during the course of CCA development following thioacetamide treatment. Thioacetamide 115-128 Wnt family member 7B Homo sapiens 0-3 27660676-13 2016 Moreover, specific inhibitors of the canonical Wnt pathway (ICG-001 and C-59) caused reduction of tumor area and number, in xenograft and thioacetamide models of CCA. Thioacetamide 138-151 Wnt family member 7B Homo sapiens 47-50 25351956-0 2014 Downregulated miR329 and miR410 promote the proliferation and invasion of oral squamous cell carcinoma by targeting Wnt-7b. mir329 14-20 Wnt family member 7B Homo sapiens 116-122 25351956-5 2014 Bioinformatic analysis predicted two miRNAs from the cluster region, miR329 and miR410, which could potentially target Wnt-7b, an activator of the Wnt-beta-catenin pathway, thereby attenuating the Wnt-beta-catenin signaling pathway in OSCC. mir329 69-75 Wnt family member 7B Homo sapiens 119-125 25351956-5 2014 Bioinformatic analysis predicted two miRNAs from the cluster region, miR329 and miR410, which could potentially target Wnt-7b, an activator of the Wnt-beta-catenin pathway, thereby attenuating the Wnt-beta-catenin signaling pathway in OSCC. mir329 69-75 Wnt family member 7B Homo sapiens 119-122 25351956-5 2014 Bioinformatic analysis predicted two miRNAs from the cluster region, miR329 and miR410, which could potentially target Wnt-7b, an activator of the Wnt-beta-catenin pathway, thereby attenuating the Wnt-beta-catenin signaling pathway in OSCC. mir329 69-75 Wnt family member 7B Homo sapiens 147-150 25351956-6 2014 Stable ectopic expression of Wnt-7b in OSCC cells overexpressing miR329 or miR410 restored proliferation and invasion capabilities abolished by these miRNA. mir329 65-71 Wnt family member 7B Homo sapiens 29-35 12239632-10 2002 WNT7B, but not WNT7A, was slightly up-regulated by all-trans retinoic acid in NT2 cells. Tretinoin 61-74 Wnt family member 7B Homo sapiens 0-5 21034933-2 2010 We have previously reported that pulmonary gene expression of Wnt2 and Wnt7b is downregulated on day 15 of gestation in the nitrofen-induced congenital diaphragmatic hernia (CDH) model. nitrofen 124-132 Wnt family member 7B Homo sapiens 71-76 24232635-9 2014 Betamethasone treatment 7 d before LPS exposure prevented the reduction in LEF1 expression, whereas betamethasone administration after LPS normalized the LPS-induced increase in Wnt7b mRNA. Betamethasone 100-113 Wnt family member 7B Homo sapiens 178-183 14514922-4 2003 METHODS: The expression of Wnt2, Wnt5a, Wnt5b, Wnt7b, and Wnt10b was defined by in situ, antisense RNA hybridisation of paraffin wax embedded sections of benign naevi and malignant melanoma. Paraffin 120-132 Wnt family member 7B Homo sapiens 47-52 9367869-6 1997 Out of nine human Wnt genes investigated, Wnt5a and Wnt7b were expressed in the parental cell line, and neomycin-, c-Ha-ras- and c-erbB2-transfected cell lines. Neomycin 104-112 Wnt family member 7B Homo sapiens 52-57