PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
11846876-2	2002	The hys1 mutants decreased chlorophyll and protein content, lowered the efficiency of photosystem II, and accumulated several senescence upregulated gene transcripts earlier than the wild-type plants.	Chlorophyll	27-38	CPR5 protein	Arabidopsis thaliana	4-8
11846876-3	2002	In addition to these senescence features, the hys1 seedlings responded more intensely to exogenously applied sugars than did wild-type seedlings in sugar-induced growth inhibition and sugar-mediated transcript accumulation, both of which are known to be regulated by the sugar sensor hexokinase.	Sugars	109-115	CPR5 protein	Arabidopsis thaliana	46-50
11846876-3	2002	In addition to these senescence features, the hys1 seedlings responded more intensely to exogenously applied sugars than did wild-type seedlings in sugar-induced growth inhibition and sugar-mediated transcript accumulation, both of which are known to be regulated by the sugar sensor hexokinase.	Sugars	109-114	CPR5 protein	Arabidopsis thaliana	46-50
11846876-3	2002	In addition to these senescence features, the hys1 seedlings responded more intensely to exogenously applied sugars than did wild-type seedlings in sugar-induced growth inhibition and sugar-mediated transcript accumulation, both of which are known to be regulated by the sugar sensor hexokinase.	Sugars	148-153	CPR5 protein	Arabidopsis thaliana	46-50
11846876-3	2002	In addition to these senescence features, the hys1 seedlings responded more intensely to exogenously applied sugars than did wild-type seedlings in sugar-induced growth inhibition and sugar-mediated transcript accumulation, both of which are known to be regulated by the sugar sensor hexokinase.	Sugars	148-153	CPR5 protein	Arabidopsis thaliana	46-50
11846876-7	2002	Although no definite conclusion can be drawn from these results, we suggest that altered sensitivity to sugars and/or enhanced efficiency of sugar signalling in the hys1/cpr5 mutant may have important roles in the initiation processes of leaf senescence and pathogen-defence responses in Arabidopsis.	Sugars	104-110	CPR5 protein	Arabidopsis thaliana	165-169
11439128-3	2001	In addition, cpr5 and cpr6 induce expression of PDF1.2, a defense-related gene associated with activation of the jasmonate/ethylene-mediated resistance pathways.	jasmonic acid	113-122	CPR5 protein	Arabidopsis thaliana	13-17
11439128-3	2001	In addition, cpr5 and cpr6 induce expression of PDF1.2, a defense-related gene associated with activation of the jasmonate/ethylene-mediated resistance pathways.	ethylene	123-131	CPR5 protein	Arabidopsis thaliana	13-17
11090217-8	2000	Furthermore, ein2 potentiates SA accumulation in cpr5 and cpr5 npr1 while dampening SA accumulation in cpr6 and cpr6 npr1.	Salicylic Acid	30-32	CPR5 protein	Arabidopsis thaliana	49-53
11439127-3	2001	We used double mutant analysis to determine the relative positions of the pad4, cpr1, cpr5, cpr6, dnd1 and dnd2 mutations in the signal transduction network leading to SA-dependent activation of defense gene expression and disease resistance.	Salicylic Acid	168-170	CPR5 protein	Arabidopsis thaliana	86-90
11439127-7	2001	In contrast, SA accumulation in the lesion-mimic mutant cpr5 is partially PAD4-independent, while in dnd1 and dnd2 mutants it is completely PAD4-independent.	Salicylic Acid	13-15	CPR5 protein	Arabidopsis thaliana	56-60
11090217-8	2000	Furthermore, ein2 potentiates SA accumulation in cpr5 and cpr5 npr1 while dampening SA accumulation in cpr6 and cpr6 npr1.	Salicylic Acid	30-32	CPR5 protein	Arabidopsis thaliana	58-62
11090217-4	2000	First, the constitutive disease resistance exhibited by cpr1, cpr5, and cpr6 is completely suppressed by the SA-deficient eds5 mutant but is only partially affected by the SA-insensitive npr1 mutant.	Salicylic Acid	109-111	CPR5 protein	Arabidopsis thaliana	62-66
9338960-3	1997	The cpr5 plants were found to be constitutively resistant to two virulent pathogens, Pseudomonas syringae pv maculicola ES4326 and Peronospora parasitica Noco2; to have endogenous expression of the pathogenesis-related gene 1 (PR-1); and to have an elevated level of salicylic acid (SA).	Salicylic Acid	267-281	CPR5 protein	Arabidopsis thaliana	4-8
9338960-3	1997	The cpr5 plants were found to be constitutively resistant to two virulent pathogens, Pseudomonas syringae pv maculicola ES4326 and Peronospora parasitica Noco2; to have endogenous expression of the pathogenesis-related gene 1 (PR-1); and to have an elevated level of salicylic acid (SA).	Salicylic Acid	283-285	CPR5 protein	Arabidopsis thaliana	4-8
9338960-5	1997	Therefore, we conclude that cpr5 acts upstream of SA in inducing SAR.	Salicylic Acid	50-52	CPR5 protein	Arabidopsis thaliana	28-32
21556325-0	2011	Arabidopsis CPR5 independently regulates seed germination and postgermination arrest of development through LOX pathway and ABA signaling.	Abscisic Acid	124-127	CPR5 protein	Arabidopsis thaliana	12-16
34222338-5	2021	We confirmed a previously published report that salicylate over-producing cpr5 plants are colonized more readily by streptomycetes but found that salicylate-deficient sid2-2 and pad4 plants had the same levels of root colonization by Streptomyces bacteria as the wild-type plants.	Salicylates	48-58	CPR5 protein	Arabidopsis thaliana	74-78
31692196-11	2020	The elevated 4C/2C ratio in cpr5 mutant is consistent with derepression of pro-endocycle regulators SIM and SMR1.	A(2)C	16-18	CPR5 protein	Arabidopsis thaliana	28-32
31692196-12	2020	The polyploidy cells (8C and 16C) may be selectively targeted to cell death which is therefore attributed to the branchless trichomes in cpr5 mutant.	N-(4-bromophenyl) 3-(4-bromophenylaminosulfonyl)benzamide	22-24	CPR5 protein	Arabidopsis thaliana	137-141
22963672-10	2013	Furthermore, other SA-accumulating mutants, cpr5 and acd6, exhibited stomatal closure and drought tolerance, and nahG suppressed the phenotype of cpr5 and acd6, as did siz1 and nahG siz1.	nahg	113-117	CPR5 protein	Arabidopsis thaliana	146-150
35137215-7	2022	Intriguingly, we found that CPR5 is an RNA-binding protein belonging to the Transformer 2 (Tra2) subfamily of the serine/arginine-rich family.	Serine	114-120	CPR5 protein	Arabidopsis thaliana	28-32
35137215-10	2022	ARGONAUTE 1 (AGO1) is one of the ASGs and, consistent with this, the ago1 mutant suppresses the cpr5 phenotype.	asgs	33-37	CPR5 protein	Arabidopsis thaliana	96-100
35201411-0	2022	Arabidopsis CPR5 plays a role in regulating nucleocytoplasmic transport of mRNAs in ethylene signaling pathway.	ethylene	84-92	CPR5 protein	Arabidopsis thaliana	12-16
35201411-1	2022	KEY MESSAGE: Arabidopsis CPR5 is involved in regulation of ethylene signaling via two different ways: interacting with the ETR1 N-terminal domains, and controlling nucleocytoplasmic transport of ethylene-related mRNAs.	ethylene	59-67	CPR5 protein	Arabidopsis thaliana	25-29
35201411-1	2022	KEY MESSAGE: Arabidopsis CPR5 is involved in regulation of ethylene signaling via two different ways: interacting with the ETR1 N-terminal domains, and controlling nucleocytoplasmic transport of ethylene-related mRNAs.	ethylene	195-203	CPR5 protein	Arabidopsis thaliana	25-29
35201411-3	2022	Previous studies showed that both RTE1 and CPR5 can directly bind to the ETR1 receptor and regulate ethylene signaling.	ethylene	100-108	CPR5 protein	Arabidopsis thaliana	43-47
35201411-4	2022	RTE1 was suggested to promote the ETR1 receptor signaling by influencing its conformation, but little is known about the regulatory mechanism of CPR5 in ethylene signaling.	ethylene	153-161	CPR5 protein	Arabidopsis thaliana	145-149
35201411-5	2022	In this study, we presented the data showing that both RTE1 and CPR5 bound to the N-terminal domains of ETR1, and regulated ethylene signaling via the ethylene receptor.	ethylene	124-132	CPR5 protein	Arabidopsis thaliana	64-68
35201411-5	2022	In this study, we presented the data showing that both RTE1 and CPR5 bound to the N-terminal domains of ETR1, and regulated ethylene signaling via the ethylene receptor.	ethylene	151-159	CPR5 protein	Arabidopsis thaliana	64-68
35201411-6	2022	On the other hand, the research provided evidence indicating that CPR5 could act as a nucleoporin to regulate the ethylene-related mRNAs export out of the nucleus, while RTE1 or its homolog (RTH) had no effect on the nucleocytoplasmic transport of mRNAs.	ethylene	114-122	CPR5 protein	Arabidopsis thaliana	66-70
35201411-8	2022	These results advance our understanding of the regulatory mechanism of CPR5 in ethylene signaling.	ethylene	79-87	CPR5 protein	Arabidopsis thaliana	71-75
33955481-8	2021	We found that loss-of-XPO4 promotes the nuclear accumulation of TPL/TPRs in the presence of elevated salicylic acid (SA), which contributes to the SA-mediated defense amplification and potentiates immune induction in the cpr5 mutant.	Salicylic Acid	101-115	CPR5 protein	Arabidopsis thaliana	221-225
33955481-8	2021	We found that loss-of-XPO4 promotes the nuclear accumulation of TPL/TPRs in the presence of elevated salicylic acid (SA), which contributes to the SA-mediated defense amplification and potentiates immune induction in the cpr5 mutant.	Salicylic Acid	117-119	CPR5 protein	Arabidopsis thaliana	221-225
33955481-10	2021	We propose that XPO4 coordinates the nuclear accumulation of TPL/TPRs, which plays a role in regulating SA-mediated defense feedback to modulate immune strength downstream of CPR5 during ETI induction.	Salicylic Acid	104-106	CPR5 protein	Arabidopsis thaliana	175-179
33955481-10	2021	We propose that XPO4 coordinates the nuclear accumulation of TPL/TPRs, which plays a role in regulating SA-mediated defense feedback to modulate immune strength downstream of CPR5 during ETI induction.	5,8,11-eicosatriynoic acid	187-190	CPR5 protein	Arabidopsis thaliana	175-179
28708312-0	2017	Arabidopsis CPR5 regulates ethylene signaling via molecular association with the ETR1 receptor.	ethylene	27-35	CPR5 protein	Arabidopsis thaliana	12-16
28708312-3	2017	The present study provides evidence demonstrating that Arabidopsis CPR5 functions as a novel ETR1 receptor-interacting protein in regulating ethylene response and signaling.	ethylene	141-149	CPR5 protein	Arabidopsis thaliana	67-71
28708312-5	2017	Genetic analyses indicated that mutant alleles of cpr5 can suppress ethylene insensitivity in both etr1-1 and etr1-2, but not in other dominant ethylene receptor mutants.	ethylene	68-76	CPR5 protein	Arabidopsis thaliana	50-54
28708312-6	2017	Overexpression of Arabidopsis CPR5 either in transgenic Arabidopsis plants, or ectopically in tobacco, significantly enhanced ethylene sensitivity.	ethylene	126-134	CPR5 protein	Arabidopsis thaliana	30-34
28708312-7	2017	These findings indicate that CPR5 plays a critical role in regulating ethylene signaling.	ethylene	70-78	CPR5 protein	Arabidopsis thaliana	29-33
25455564-5	2014	Upon ETI induction, CKIs are released from CPR5 to cause overactivation of another core cell-cycle regulator, E2F.	5,8,11-eicosatriynoic acid	5-8	CPR5 protein	Arabidopsis thaliana	43-47
22963672-10	2013	Furthermore, other SA-accumulating mutants, cpr5 and acd6, exhibited stomatal closure and drought tolerance, and nahG suppressed the phenotype of cpr5 and acd6, as did siz1 and nahG siz1.	Salicylic Acid	19-21	CPR5 protein	Arabidopsis thaliana	44-48
22963672-10	2013	Furthermore, other SA-accumulating mutants, cpr5 and acd6, exhibited stomatal closure and drought tolerance, and nahG suppressed the phenotype of cpr5 and acd6, as did siz1 and nahG siz1.	Salicylic Acid	19-21	CPR5 protein	Arabidopsis thaliana	146-150
21556325-2	2011	Here, we reported on the functional characterization of Arabidopsis CPR5 in the ABA signaling and LOX pathways.	Abscisic Acid	80-83	CPR5 protein	Arabidopsis thaliana	68-72
21556325-3	2011	The cpr5 mutant was hypersensitive to ABA in the seed germination, cotyledon greening and root growth, whereas transgenic plants overexpressing CPR5 were insensitive.	Abscisic Acid	38-41	CPR5 protein	Arabidopsis thaliana	4-8
21556325-4	2011	Genetic analysis demonstrated that CPR5 gene may be located downstream of the ABI1 in the ABA signaling pathway.	Abscisic Acid	90-93	CPR5 protein	Arabidopsis thaliana	35-39
21556325-5	2011	However, the cpr5 mutant showed an ABA independent drought-resistant phenotype.	Abscisic Acid	35-38	CPR5 protein	Arabidopsis thaliana	13-17
21556325-6	2011	It was also found that the cpr5 mutant was hypersensitive to NDGA and NDGA treatment aggravated the ABA-induced delay in the seed germination and cotyledon greening.	Abscisic Acid	100-103	CPR5 protein	Arabidopsis thaliana	27-31
21556325-7	2011	Taken together, these results suggest that the CPR5 plays a regulatory role in the regulation of seed germination and early seedling growth through ABA and LOX pathways independently.	Abscisic Acid	148-151	CPR5 protein	Arabidopsis thaliana	47-51
19839340-6	2009	However, there was a decrease in the photosynthetic efficiency and even a stress of the cpr5 leaves with 100 and 300 micromol x L(-1) SA treatment.	2-chloro-10-(4'(N-beta-hydroxyethyl)piperazinyl-1')acetylphenothiazine	134-136	CPR5 protein	Arabidopsis thaliana	88-92
22046278-7	2011	In cpr5 expression of genes encoding various Cyclic Nucleotide Gated Channels (CNGCs) are uniquely elevated in leaves.	Nucleotides, Cyclic	45-62	CPR5 protein	Arabidopsis thaliana	3-7
18485217-1	2008	BACKGROUND: The Arabidopsis thaliana CONSTITUTIVE EXPRESSOR OF PATHOGENESIS-RELATED GENES5 (CPR5) gene has been previously implicated in disease resistance, cell proliferation, cell death, and sugar sensing, and encodes a putative membrane protein of unknown biochemical function.	Sugars	193-198	CPR5 protein	Arabidopsis thaliana	37-90
18721314-7	2008	The results demonstrate that many genes in the ROS gene network show at least fivefold increases in transcripts in comparison with those of wild-type plants, suggesting that presymptomatic cpr5/old1 mutants are in a state of high-cellular oxidative stress.	Reactive Oxygen Species	47-50	CPR5 protein	Arabidopsis thaliana	189-193
18485217-1	2008	BACKGROUND: The Arabidopsis thaliana CONSTITUTIVE EXPRESSOR OF PATHOGENESIS-RELATED GENES5 (CPR5) gene has been previously implicated in disease resistance, cell proliferation, cell death, and sugar sensing, and encodes a putative membrane protein of unknown biochemical function.	Sugars	193-198	CPR5 protein	Arabidopsis thaliana	92-96
18485217-5	2008	Consistent with this, leaf cell walls of cpr5 plants contained significantly less paracrystalline cellulose and had an altered wall carbohydrate composition.	paracrystalline cellulose	82-107	CPR5 protein	Arabidopsis thaliana	41-45
18485217-5	2008	Consistent with this, leaf cell walls of cpr5 plants contained significantly less paracrystalline cellulose and had an altered wall carbohydrate composition.	Carbohydrates	132-144	CPR5 protein	Arabidopsis thaliana	41-45
18307823-5	2008	Transcription of these genes is strongly induced in response to salicylic acid (SA) and its functional synthetic analogue benzothiadiazole S-methylester (BTH), a number of biotic and abiotic stresses including many SA-mediated SAR-inducing conditions, as well as in the constitutive SAR expressing mutants cpr5 and mpk4 which have elevated SA levels.	Salicylic Acid	64-78	CPR5 protein	Arabidopsis thaliana	306-310
18307823-5	2008	Transcription of these genes is strongly induced in response to salicylic acid (SA) and its functional synthetic analogue benzothiadiazole S-methylester (BTH), a number of biotic and abiotic stresses including many SA-mediated SAR-inducing conditions, as well as in the constitutive SAR expressing mutants cpr5 and mpk4 which have elevated SA levels.	Salicylic Acid	80-82	CPR5 protein	Arabidopsis thaliana	306-310
18307823-5	2008	Transcription of these genes is strongly induced in response to salicylic acid (SA) and its functional synthetic analogue benzothiadiazole S-methylester (BTH), a number of biotic and abiotic stresses including many SA-mediated SAR-inducing conditions, as well as in the constitutive SAR expressing mutants cpr5 and mpk4 which have elevated SA levels.	benzo-1,2,3-thiadiazole	122-138	CPR5 protein	Arabidopsis thaliana	306-310
18307823-5	2008	Transcription of these genes is strongly induced in response to salicylic acid (SA) and its functional synthetic analogue benzothiadiazole S-methylester (BTH), a number of biotic and abiotic stresses including many SA-mediated SAR-inducing conditions, as well as in the constitutive SAR expressing mutants cpr5 and mpk4 which have elevated SA levels.	bth	154-157	CPR5 protein	Arabidopsis thaliana	306-310
18307823-5	2008	Transcription of these genes is strongly induced in response to salicylic acid (SA) and its functional synthetic analogue benzothiadiazole S-methylester (BTH), a number of biotic and abiotic stresses including many SA-mediated SAR-inducing conditions, as well as in the constitutive SAR expressing mutants cpr5 and mpk4 which have elevated SA levels.	Salicylic Acid	215-217	CPR5 protein	Arabidopsis thaliana	306-310
18307823-5	2008	Transcription of these genes is strongly induced in response to salicylic acid (SA) and its functional synthetic analogue benzothiadiazole S-methylester (BTH), a number of biotic and abiotic stresses including many SA-mediated SAR-inducing conditions, as well as in the constitutive SAR expressing mutants cpr5 and mpk4 which have elevated SA levels.	Salicylic Acid	215-217	CPR5 protein	Arabidopsis thaliana	306-310
17720689-1	2007	The Arabidopsis mutant hypersenescence 1 (hys1), that is allelic to constitutive expresser of pathogenesis-related genes 5 (cpr5), displays phenotypes related to glucose signalling and defence responses.	Glucose	162-169	CPR5 protein	Arabidopsis thaliana	42-46
17720689-2	2007	In the present study, it is shown that the hys1 mutation boosts the inhibitory effects of glucose upon the greening of seedlings and reduces the antagonistic activities of ethylene and cytokinin toward this inhibition.	Glucose	90-97	CPR5 protein	Arabidopsis thaliana	43-47
17720689-2	2007	In the present study, it is shown that the hys1 mutation boosts the inhibitory effects of glucose upon the greening of seedlings and reduces the antagonistic activities of ethylene and cytokinin toward this inhibition.	ethylene	172-180	CPR5 protein	Arabidopsis thaliana	43-47
17720689-4	2007	However, disruption of the gene encoding hexokinase1 (HXK1), which acts as a glucose sensor, partially suppressed the glucose hypersensitive phenotype of the hys1 mutant.	Glucose	77-84	CPR5 protein	Arabidopsis thaliana	158-162
17720689-4	2007	However, disruption of the gene encoding hexokinase1 (HXK1), which acts as a glucose sensor, partially suppressed the glucose hypersensitive phenotype of the hys1 mutant.	Glucose	118-125	CPR5 protein	Arabidopsis thaliana	158-162
17720689-5	2007	These results thus suggest that the hys1 mutation promotes a process associated with the HXK1-mediated glucose response during greening.	Glucose	103-110	CPR5 protein	Arabidopsis thaliana	36-40
17720689-6	2007	By contrast, additional hys1 phenotypes, including an increase in salicylic acid (SA), production of abnormal trichomes, and early senescence, were not suppressed by the loss of HXK1.	Salicylic Acid	66-80	CPR5 protein	Arabidopsis thaliana	24-28
17720689-6	2007	By contrast, additional hys1 phenotypes, including an increase in salicylic acid (SA), production of abnormal trichomes, and early senescence, were not suppressed by the loss of HXK1.	Salicylic Acid	82-84	CPR5 protein	Arabidopsis thaliana	24-28
17720689-7	2007	Surprisingly, the hxk1 and hys1 mutations acted synergistically towards an increased SA accumulation.	Salicylic Acid	85-87	CPR5 protein	Arabidopsis thaliana	27-31
17720689-8	2007	Hence, HYS1/CPR5 appears to be a versatile protein that modulates both the HXK1-mediated glucose response and various HXK1-indepndent processes that are involved in growth control.	Glucose	89-96	CPR5 protein	Arabidopsis thaliana	7-11
17720689-8	2007	Hence, HYS1/CPR5 appears to be a versatile protein that modulates both the HXK1-mediated glucose response and various HXK1-indepndent processes that are involved in growth control.	Glucose	89-96	CPR5 protein	Arabidopsis thaliana	12-16