PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
33850086-6	2021	Genetic crossing experiments followed by physiological and immunocytochemical analyses revealed that Rpd3 mutations suppressed these defects induced by dFIG 4 knockdown.	dfig	152-156	Histone deacetylase 1	Drosophila melanogaster	101-105
28447071-1	2017	BACKGROUND: Rpd3 is a conserved histone deacetylase that removes acetyl groups from lysine residues within histones and other proteins.	Lysine	84-90	Histone deacetylase 1	Drosophila melanogaster	12-16
20962230-8	2010	HDAC (histone deacetylase) inhibitors, SAHA (suberoylanilide hydroxamic acid) and PBA (phenylbutyrate), that upregulated NR1 partially rescued the learning disturbance.	Vorinostat	45-76	Histone deacetylase 1	Drosophila melanogaster	0-4
23519136-5	2013	Here, we hypothesize that chromatin landscape changes induced by ecdysone surges direct the HDAC1- or HP1a-containing Fru complex to distinct targets, thereby allowing them to switch the neuronal sexual fate in the brain.	Ecdysone	65-73	Histone deacetylase 1	Drosophila melanogaster	92-97
16391236-2	2006	Here, we report genetic and molecular evidence that the histone acetyltransferase (HAT) Chameau and the histone deacetylase DRpd3 act as antagonistic cofactors of DJun and DFos to modulate JNK-dependent transcription during thorax metamorphosis and JNK-induced apoptosis in Drosophila.	Deferoxamine	172-176	Histone deacetylase 1	Drosophila melanogaster	124-129
16632473-15	2006	3) The anti-proliferative and transcriptional effects of trichostatin are largely recapitulated by the loss of DHDAC1.	trichostatin A	57-69	Histone deacetylase 1	Drosophila melanogaster	111-117
20962230-8	2010	HDAC (histone deacetylase) inhibitors, SAHA (suberoylanilide hydroxamic acid) and PBA (phenylbutyrate), that upregulated NR1 partially rescued the learning disturbance.	Phenylbutyrates	87-101	Histone deacetylase 1	Drosophila melanogaster	0-4
20962230-8	2010	HDAC (histone deacetylase) inhibitors, SAHA (suberoylanilide hydroxamic acid) and PBA (phenylbutyrate), that upregulated NR1 partially rescued the learning disturbance.	Phenylbutyrates	87-101	Histone deacetylase 1	Drosophila melanogaster	6-25
16391236-3	2006	We demonstrate in cultured cells that DFos phosphorylation mediated by JNK signaling plays a central role in coordinating the dynamics of Chameau and DRpd3 recruitment and function at AP-1-responsive promoters.	Deferoxamine	38-42	Histone deacetylase 1	Drosophila melanogaster	150-155
12576549-0	2003	Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington"s disease.	Vorinostat	0-31	Histone deacetylase 1	Drosophila melanogaster	35-54
15102712-5	2004	We studied the therapeutic effects of sodium butyrate (SB), an HDAC inhibitor, in a transgenic mouse model of SBMA.	Butyric Acid	55-57	Histone deacetylase 1	Drosophila melanogaster	63-67
12576549-4	2003	To further explore the therapeutic potential of HDAC inhibitors, we have conducted preclinical trials with suberoylanilide hydroxamic acid (SAHA), a potent HDAC inhibitor, in the R6/2 HD mouse model.	Vorinostat	107-138	Histone deacetylase 1	Drosophila melanogaster	156-160
11278256-6	2001	Transcriptional repression by Gal4-dHDAC1 was blocked by the deacetylase inhibitor, FR901228, and thus, deacetylase activity correlates with repression.	romidepsin	84-92	Histone deacetylase 1	Drosophila melanogaster	35-41
11607033-7	2001	In vivo, HDAC inhibitors arrest ongoing progressive neuronal degeneration induced by polyglutamine repeat expansion, and they reduce lethality in two Drosophila models of polyglutamine disease.	polyglutamine	85-98	Histone deacetylase 1	Drosophila melanogaster	9-13
10485845-4	1999	Protein-protein interaction assays suggest that Gro and Rpd3 form a complex in vivo and that they interact directly via the glycine/proline rich (GP) domain in Gro.	Glycine	124-131	Histone deacetylase 1	Drosophila melanogaster	56-60
10485845-4	1999	Protein-protein interaction assays suggest that Gro and Rpd3 form a complex in vivo and that they interact directly via the glycine/proline rich (GP) domain in Gro.	Proline	132-139	Histone deacetylase 1	Drosophila melanogaster	56-60