PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 34046684-2 2021 In Arabidopsis (Arabidopsis thaliana), cryptochrome 1 (CRY1) mediates blue light-induced photomorphogenesis, which is characterized by reduced hypocotyl elongation and enhanced anthocyanin production, whereas gibberellin (GA) signaling mediated by the GA receptor GA-INSENSITIVE DWARF1 (GID1) and DELLA proteins promotes hypocotyl elongation and inhibits anthocyanin accumulation. Anthocyanins 177-188 cryptochrome 1 Arabidopsis thaliana 39-53 34046684-2 2021 In Arabidopsis (Arabidopsis thaliana), cryptochrome 1 (CRY1) mediates blue light-induced photomorphogenesis, which is characterized by reduced hypocotyl elongation and enhanced anthocyanin production, whereas gibberellin (GA) signaling mediated by the GA receptor GA-INSENSITIVE DWARF1 (GID1) and DELLA proteins promotes hypocotyl elongation and inhibits anthocyanin accumulation. Anthocyanins 177-188 cryptochrome 1 Arabidopsis thaliana 55-59 34046684-2 2021 In Arabidopsis (Arabidopsis thaliana), cryptochrome 1 (CRY1) mediates blue light-induced photomorphogenesis, which is characterized by reduced hypocotyl elongation and enhanced anthocyanin production, whereas gibberellin (GA) signaling mediated by the GA receptor GA-INSENSITIVE DWARF1 (GID1) and DELLA proteins promotes hypocotyl elongation and inhibits anthocyanin accumulation. Anthocyanins 355-366 cryptochrome 1 Arabidopsis thaliana 39-53 34046684-2 2021 In Arabidopsis (Arabidopsis thaliana), cryptochrome 1 (CRY1) mediates blue light-induced photomorphogenesis, which is characterized by reduced hypocotyl elongation and enhanced anthocyanin production, whereas gibberellin (GA) signaling mediated by the GA receptor GA-INSENSITIVE DWARF1 (GID1) and DELLA proteins promotes hypocotyl elongation and inhibits anthocyanin accumulation. Anthocyanins 355-366 cryptochrome 1 Arabidopsis thaliana 55-59 34046684-4 2021 Here, we show that CRY1 signaling involves the inhibition of GA signaling through repression of GA-induced degradation of DELLA proteins. Gallium 61-63 cryptochrome 1 Arabidopsis thaliana 19-23 30763615-0 2019 The Blue-Light Receptor CRY1 Interacts with BZR1 and BIN2 to Modulate the Phosphorylation and Nuclear Function of BZR1 in Repressing BR Signaling in Arabidopsis. Brassinosteroids 133-135 cryptochrome 1 Arabidopsis thaliana 24-28 32935701-0 2020 ATP binding promotes light-induced structural changes to the protein moiety of Arabidopsis cryptochrome 1. Adenosine Triphosphate 0-3 cryptochrome 1 Arabidopsis thaliana 91-105 32935701-3 2020 Studies have shown that cryptochrome 1 from Arabidopsis thaliana (AtCRY1) can bind ATP at its photolyase homology region (PHR), resulting in accumulation of FADH form. Adenosine Triphosphate 83-86 cryptochrome 1 Arabidopsis thaliana 24-38 32935701-3 2020 Studies have shown that cryptochrome 1 from Arabidopsis thaliana (AtCRY1) can bind ATP at its photolyase homology region (PHR), resulting in accumulation of FADH form. Adenosine Triphosphate 83-86 cryptochrome 1 Arabidopsis thaliana 66-72 32935701-4 2020 This study used light-induced difference Fourier transform infrared spectroscopy to investigate how ATP influences structural changes in AtCRY1-PHR during the photoreaction. Adenosine Triphosphate 100-103 cryptochrome 1 Arabidopsis thaliana 137-143 31514232-9 2020 Altogether, our results suggest that the direct repression of auxin-responsive gene expression mediated by the interactions of CRY1 and phyB with ARFs constitutes a new layer of the regulatory mechanisms by which light inhibits auxin-induced hypocotyl elongation. Indoleacetic Acids 62-67 cryptochrome 1 Arabidopsis thaliana 127-131 31084870-3 2019 Our previous study found that ferredoxin NADP+ oxidoreductase (FNR1) and the blue-light receptor cryptochrome 1 (CRY1) are involved in nitrogen-regulated flowering-time control. Nitrogen 135-143 cryptochrome 1 Arabidopsis thaliana 97-111 31084870-3 2019 Our previous study found that ferredoxin NADP+ oxidoreductase (FNR1) and the blue-light receptor cryptochrome 1 (CRY1) are involved in nitrogen-regulated flowering-time control. Nitrogen 135-143 cryptochrome 1 Arabidopsis thaliana 113-117 30941890-4 2020 Here, we report that depleting sucrose from the medium or adding gibberellic acids (GAs) can partially restore the defects in phototropic curvature of the phot1 phot2 double mutants under high-intensity blue light; this restoration does not occur in phot1 phot2 cry1 cry2 quadruple mutants and nph3 (nonphototropic hypocotyl 3) mutants which were impaired phototropic response in sucrose-containing medium. Sucrose 31-38 cryptochrome 1 Arabidopsis thaliana 262-266 30941890-4 2020 Here, we report that depleting sucrose from the medium or adding gibberellic acids (GAs) can partially restore the defects in phototropic curvature of the phot1 phot2 double mutants under high-intensity blue light; this restoration does not occur in phot1 phot2 cry1 cry2 quadruple mutants and nph3 (nonphototropic hypocotyl 3) mutants which were impaired phototropic response in sucrose-containing medium. gibberellic acid 65-82 cryptochrome 1 Arabidopsis thaliana 262-266 31822614-10 2019 A VP motif present in CRY1 is also essential for binding to COP1. valyl-prolyl-proline 2-4 cryptochrome 1 Arabidopsis thaliana 22-26 30763615-3 2019 We report here that CRY1 inhibits hypocotyl elongation by repressing brassinosteroid (BR) signaling. Brassinosteroids 69-84 cryptochrome 1 Arabidopsis thaliana 20-24 30131420-0 2018 Photoexcited CRYPTOCHROME1 Interacts with Dephosphorylated BES1 to Regulate Brassinosteroid Signaling and Photomorphogenesis in Arabidopsis. Brassinosteroids 76-91 cryptochrome 1 Arabidopsis thaliana 13-26 30044014-3 2018 The two Arabidopsis thaliana cryptochromes, cry1 and cry2, and the plant-type cryptochrome CPH1 from Chlamydomonas rheinhardtii bind ATP and other nucleotides. Adenosine Triphosphate 133-136 cryptochrome 1 Arabidopsis thaliana 44-48 30131420-3 2018 Brassinosteroid (BR) is a key phytohormone involved in the repression of photomorphogenesis, and here, we show that the signaling mechanism of Arabidopsis CRY1 involves the inhibition of BR signaling. Brassinosteroids 0-15 cryptochrome 1 Arabidopsis thaliana 155-159 30131420-3 2018 Brassinosteroid (BR) is a key phytohormone involved in the repression of photomorphogenesis, and here, we show that the signaling mechanism of Arabidopsis CRY1 involves the inhibition of BR signaling. Brassinosteroids 17-19 cryptochrome 1 Arabidopsis thaliana 155-159 30131420-6 2018 In addition, CRY1 and CRY2 interact specifically with dephosphorylated BES1, the physiologically active form of BES1 that is activated by BR in a blue light-dependent manner. Brassinosteroids 138-140 cryptochrome 1 Arabidopsis thaliana 13-17 30131420-8 2018 Our study suggests that the blue light-dependent, BR-induced interaction of CRY1 with BES1 is a tightly regulated mechanism by which plants optimize photomorphogenesis according to the availability of external light and internal BR signals. Brassinosteroids 50-52 cryptochrome 1 Arabidopsis thaliana 76-80 30131420-8 2018 Our study suggests that the blue light-dependent, BR-induced interaction of CRY1 with BES1 is a tightly regulated mechanism by which plants optimize photomorphogenesis according to the availability of external light and internal BR signals. Brassinosteroids 229-231 cryptochrome 1 Arabidopsis thaliana 76-80 29864723-8 2018 GMF impacts on phytochrome-regulated gene expression could be attributed to alterations in phytochrome protein abundance that were also dependent on the presence of cry1, cry2 and phot1. Gemifloxacin 0-3 cryptochrome 1 Arabidopsis thaliana 165-169 29860272-5 2018 Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner. Brassinosteroids 132-147 cryptochrome 1 Arabidopsis thaliana 31-35 29860272-5 2018 Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner. Brassinosteroids 149-151 cryptochrome 1 Arabidopsis thaliana 31-35 29860272-5 2018 Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner. gibberellin acid 157-173 cryptochrome 1 Arabidopsis thaliana 31-35 29860272-5 2018 Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner. Gallium 175-177 cryptochrome 1 Arabidopsis thaliana 31-35 25728686-3 2015 Recently, it has been shown that Arabidopsis cry1 activation by blue light also results in direct enzymatic conversion of molecular oxygen (O2 ) to reactive oxygen species (ROS) and hydrogen peroxide (H2 O2 ) in vitro. Oxygen 132-138 cryptochrome 1 Arabidopsis thaliana 45-49 27423124-2 2016 Photon absorption by Arabidopsis cryptochromes cry1 and cry2 initiates electron transfer to the oxidized flavin cofactor (FADox) and formation of the presumed biological signaling state FADH . 4,6-dinitro-o-cresol 105-111 cryptochrome 1 Arabidopsis thaliana 47-51 27423124-2 2016 Photon absorption by Arabidopsis cryptochromes cry1 and cry2 initiates electron transfer to the oxidized flavin cofactor (FADox) and formation of the presumed biological signaling state FADH . fadox 122-127 cryptochrome 1 Arabidopsis thaliana 47-51 27020113-8 2016 For Arabidopsis thaliana cryptochrome 1 (AtCry1) we find that spin relaxation implies optimal radical pair lifetimes of the order of microseconds, and that flavin-Z pairs are less affected by relaxation than flavin-tryptophan pairs. 4,6-dinitro-o-cresol 156-162 cryptochrome 1 Arabidopsis thaliana 41-47 27020113-8 2016 For Arabidopsis thaliana cryptochrome 1 (AtCry1) we find that spin relaxation implies optimal radical pair lifetimes of the order of microseconds, and that flavin-Z pairs are less affected by relaxation than flavin-tryptophan pairs. flavin-tryptophan 209-226 cryptochrome 1 Arabidopsis thaliana 25-39 27020113-8 2016 For Arabidopsis thaliana cryptochrome 1 (AtCry1) we find that spin relaxation implies optimal radical pair lifetimes of the order of microseconds, and that flavin-Z pairs are less affected by relaxation than flavin-tryptophan pairs. flavin-tryptophan 209-226 cryptochrome 1 Arabidopsis thaliana 41-47 26649273-5 2015 This in vitro study extends earlier investigations of the oxidation of Arabidopsis cryptochrome1 by molecular oxygen and demonstrates that, under some conditions, a more complex model for oxidation of the flavin than was previously proposed is required to accommodate the spectral evidence (see P. Muller and M. Ahmad (2011) J. Biol. Oxygen 110-116 cryptochrome 1 Arabidopsis thaliana 83-96 26649273-5 2015 This in vitro study extends earlier investigations of the oxidation of Arabidopsis cryptochrome1 by molecular oxygen and demonstrates that, under some conditions, a more complex model for oxidation of the flavin than was previously proposed is required to accommodate the spectral evidence (see P. Muller and M. Ahmad (2011) J. Biol. 4,6-dinitro-o-cresol 205-211 cryptochrome 1 Arabidopsis thaliana 83-96 28634231-0 2017 Hyperactivity of the Arabidopsis cryptochrome (cry1) L407F mutant is caused by a structural alteration close to the cry1 ATP-binding site. Adenosine Triphosphate 121-124 cryptochrome 1 Arabidopsis thaliana 47-51 28634231-0 2017 Hyperactivity of the Arabidopsis cryptochrome (cry1) L407F mutant is caused by a structural alteration close to the cry1 ATP-binding site. Adenosine Triphosphate 121-124 cryptochrome 1 Arabidopsis thaliana 116-120 28634231-3 2017 The cry1 photocycle is initiated by light absorption by its FAD chromophore, which is most likely fully oxidized (FADox) in the dark state and photoreduced to the neutral flavin semiquinone (FADH ) in its lit state. fadox 114-119 cryptochrome 1 Arabidopsis thaliana 4-8 28634231-3 2017 The cry1 photocycle is initiated by light absorption by its FAD chromophore, which is most likely fully oxidized (FADox) in the dark state and photoreduced to the neutral flavin semiquinone (FADH ) in its lit state. flavin semiquinone 171-189 cryptochrome 1 Arabidopsis thaliana 4-8 28634231-3 2017 The cry1 photocycle is initiated by light absorption by its FAD chromophore, which is most likely fully oxidized (FADox) in the dark state and photoreduced to the neutral flavin semiquinone (FADH ) in its lit state. 1,5-dihydro-FAD 191-195 cryptochrome 1 Arabidopsis thaliana 4-8 28634231-5 2017 The previously characterized L407F mutant allele of Arabidopsis cry1 is biologically hyperactive and seems to mimic the ATP-bound state of cry1, but the reason for this phenotypic change is unclear. Adenosine Triphosphate 120-123 cryptochrome 1 Arabidopsis thaliana 64-68 28634231-5 2017 The previously characterized L407F mutant allele of Arabidopsis cry1 is biologically hyperactive and seems to mimic the ATP-bound state of cry1, but the reason for this phenotypic change is unclear. Adenosine Triphosphate 120-123 cryptochrome 1 Arabidopsis thaliana 139-143 28634231-6 2017 Here, we show that cry1L407F can still bind ATP, has less pronounced photoreduction and formation of FADH than wild-type cry1, and has a dark reversion rate 1.7 times lower than that of the wild type. Adenosine Triphosphate 44-47 cryptochrome 1 Arabidopsis thaliana 19-23 28634231-8 2017 Moreover, we show that ATP binds to cry1 in both the dark and the lit states. Adenosine Triphosphate 23-26 cryptochrome 1 Arabidopsis thaliana 36-40 28634231-10 2017 Finally, we show that a recently discovered chemical inhibitor of cry1, 3-bromo-7-nitroindazole, competes for ATP binding and thereby diminishes FADH formation, which demonstrates that both processes are important for cry1 function. 3-bromo-7-nitroindazole 72-95 cryptochrome 1 Arabidopsis thaliana 66-70 28634231-10 2017 Finally, we show that a recently discovered chemical inhibitor of cry1, 3-bromo-7-nitroindazole, competes for ATP binding and thereby diminishes FADH formation, which demonstrates that both processes are important for cry1 function. 3-bromo-7-nitroindazole 72-95 cryptochrome 1 Arabidopsis thaliana 219-223 28634231-10 2017 Finally, we show that a recently discovered chemical inhibitor of cry1, 3-bromo-7-nitroindazole, competes for ATP binding and thereby diminishes FADH formation, which demonstrates that both processes are important for cry1 function. Adenosine Triphosphate 110-113 cryptochrome 1 Arabidopsis thaliana 66-70 28634231-10 2017 Finally, we show that a recently discovered chemical inhibitor of cry1, 3-bromo-7-nitroindazole, competes for ATP binding and thereby diminishes FADH formation, which demonstrates that both processes are important for cry1 function. Adenosine Triphosphate 110-113 cryptochrome 1 Arabidopsis thaliana 219-223 27598690-4 2017 However, GA levels in cry1/cry2 mutants in near-null magnetic field were similar to controls. Gallium 9-11 cryptochrome 1 Arabidopsis thaliana 22-26 27598690-6 2017 In contrast, expressions of all the detected GA biosynthetic and signaling genes in cry1/cry2 mutants were not affected by near-null magnetic field. Gallium 45-47 cryptochrome 1 Arabidopsis thaliana 84-88 27325772-0 2016 Arabidopsis cryptochrome 1 functions in nitrogen regulation of flowering. Nitrogen 40-48 cryptochrome 1 Arabidopsis thaliana 12-26 27446119-2 2016 Arabidopsis cryptochromes (cry1 and cry2) absorb light through an oxidized flavin (FADox) cofactor which undergoes reduction to both FADH and FADH(-) redox states. 4,6-dinitro-o-cresol 75-81 cryptochrome 1 Arabidopsis thaliana 27-31 27446119-2 2016 Arabidopsis cryptochromes (cry1 and cry2) absorb light through an oxidized flavin (FADox) cofactor which undergoes reduction to both FADH and FADH(-) redox states. fadox 83-88 cryptochrome 1 Arabidopsis thaliana 27-31 27446119-5 2016 Our model fits the experimental data for flavin photoconversion in vitro for both cry1 and cry2, providing calculated quantum yields which are significantly lower in cry1 than for cry2. 4,6-dinitro-o-cresol 41-47 cryptochrome 1 Arabidopsis thaliana 82-86 27446119-5 2016 Our model fits the experimental data for flavin photoconversion in vitro for both cry1 and cry2, providing calculated quantum yields which are significantly lower in cry1 than for cry2. 4,6-dinitro-o-cresol 41-47 cryptochrome 1 Arabidopsis thaliana 166-170 27014317-3 2016 Most recently, CRY1 N terminus (CNT1) has been found to be involved in CRY1 signaling independent of CCT1, and implicated in the inhibition of gibberellin acids (GA)/brassinosteroids (BR)/auxin-responsive gene expression. gibberellin acids 143-160 cryptochrome 1 Arabidopsis thaliana 15-19 27014317-3 2016 Most recently, CRY1 N terminus (CNT1) has been found to be involved in CRY1 signaling independent of CCT1, and implicated in the inhibition of gibberellin acids (GA)/brassinosteroids (BR)/auxin-responsive gene expression. Gallium 162-164 cryptochrome 1 Arabidopsis thaliana 15-19 27014317-3 2016 Most recently, CRY1 N terminus (CNT1) has been found to be involved in CRY1 signaling independent of CCT1, and implicated in the inhibition of gibberellin acids (GA)/brassinosteroids (BR)/auxin-responsive gene expression. Brassinosteroids 166-182 cryptochrome 1 Arabidopsis thaliana 15-19 26106155-4 2015 We tested this hypothesis by analyzing mutations of Arabidopsis cryptochrome 1 (CRY1) altered in each of the three Trp-triad tryptophan residues (W324, W377, and W400). Tryptophan 115-118 cryptochrome 1 Arabidopsis thaliana 64-78 26106155-4 2015 We tested this hypothesis by analyzing mutations of Arabidopsis cryptochrome 1 (CRY1) altered in each of the three Trp-triad tryptophan residues (W324, W377, and W400). Tryptophan 115-118 cryptochrome 1 Arabidopsis thaliana 80-84 26106155-4 2015 We tested this hypothesis by analyzing mutations of Arabidopsis cryptochrome 1 (CRY1) altered in each of the three Trp-triad tryptophan residues (W324, W377, and W400). Tryptophan 125-135 cryptochrome 1 Arabidopsis thaliana 64-78 26106155-4 2015 We tested this hypothesis by analyzing mutations of Arabidopsis cryptochrome 1 (CRY1) altered in each of the three Trp-triad tryptophan residues (W324, W377, and W400). Tryptophan 125-135 cryptochrome 1 Arabidopsis thaliana 80-84 26106155-5 2015 Surprisingly, in contrast to a previous report all photoreduction-deficient Trp-triad mutations of CRY1 remained physiologically and biochemically active in Arabidopsis plants. Tryptophan 76-79 cryptochrome 1 Arabidopsis thaliana 99-103 25728686-3 2015 Recently, it has been shown that Arabidopsis cry1 activation by blue light also results in direct enzymatic conversion of molecular oxygen (O2 ) to reactive oxygen species (ROS) and hydrogen peroxide (H2 O2 ) in vitro. Oxygen 140-142 cryptochrome 1 Arabidopsis thaliana 45-49 25728686-3 2015 Recently, it has been shown that Arabidopsis cry1 activation by blue light also results in direct enzymatic conversion of molecular oxygen (O2 ) to reactive oxygen species (ROS) and hydrogen peroxide (H2 O2 ) in vitro. Reactive Oxygen Species 148-171 cryptochrome 1 Arabidopsis thaliana 45-49 25728686-3 2015 Recently, it has been shown that Arabidopsis cry1 activation by blue light also results in direct enzymatic conversion of molecular oxygen (O2 ) to reactive oxygen species (ROS) and hydrogen peroxide (H2 O2 ) in vitro. Reactive Oxygen Species 173-176 cryptochrome 1 Arabidopsis thaliana 45-49 25728686-3 2015 Recently, it has been shown that Arabidopsis cry1 activation by blue light also results in direct enzymatic conversion of molecular oxygen (O2 ) to reactive oxygen species (ROS) and hydrogen peroxide (H2 O2 ) in vitro. Hydrogen Peroxide 182-199 cryptochrome 1 Arabidopsis thaliana 45-49 25728686-3 2015 Recently, it has been shown that Arabidopsis cry1 activation by blue light also results in direct enzymatic conversion of molecular oxygen (O2 ) to reactive oxygen species (ROS) and hydrogen peroxide (H2 O2 ) in vitro. Hydrogen Peroxide 201-206 cryptochrome 1 Arabidopsis thaliana 45-49 25728686-4 2015 Here we explored whether direct enzymatic synthesis of ROS by Arabidopsis cry1 can play a physiological role in vivo. Reactive Oxygen Species 55-58 cryptochrome 1 Arabidopsis thaliana 74-78 25728686-5 2015 ROS formation resulting from cry1 expression was measured by fluorescence assay in insect cell cultures and in Arabidopsis protoplasts from cryptochrome mutant seedlings. Reactive Oxygen Species 0-3 cryptochrome 1 Arabidopsis thaliana 29-33 25728686-7 2015 We found that ROS formation results from cry1 activation and induces cell death in insect cell cultures. Reactive Oxygen Species 14-17 cryptochrome 1 Arabidopsis thaliana 41-45 26179959-3 2015 In a prior study, it has also been shown that Arabidopsis cry1 activation by blue light results in direct enzymatic conversion of molecular oxygen (O2) to ROS (reactive oxygen species) in vivo leading to cell death in overexpressing lines. Oxygen 140-146 cryptochrome 1 Arabidopsis thaliana 58-62 26179959-3 2015 In a prior study, it has also been shown that Arabidopsis cry1 activation by blue light results in direct enzymatic conversion of molecular oxygen (O2) to ROS (reactive oxygen species) in vivo leading to cell death in overexpressing lines. Oxygen 148-150 cryptochrome 1 Arabidopsis thaliana 58-62 26179959-3 2015 In a prior study, it has also been shown that Arabidopsis cry1 activation by blue light results in direct enzymatic conversion of molecular oxygen (O2) to ROS (reactive oxygen species) in vivo leading to cell death in overexpressing lines. Reactive Oxygen Species 155-158 cryptochrome 1 Arabidopsis thaliana 58-62 26179959-3 2015 In a prior study, it has also been shown that Arabidopsis cry1 activation by blue light results in direct enzymatic conversion of molecular oxygen (O2) to ROS (reactive oxygen species) in vivo leading to cell death in overexpressing lines. Reactive Oxygen Species 160-183 cryptochrome 1 Arabidopsis thaliana 58-62 26313597-2 2015 In plants, cryptochrome (cry1, cry2) biological activity has been linked to flavin photoreduction via an electron transport chain to the protein surface comprising 3 evolutionarily conserved tryptophan residues known as the "Trp triad." 4,6-dinitro-o-cresol 76-82 cryptochrome 1 Arabidopsis thaliana 25-29 26313597-2 2015 In plants, cryptochrome (cry1, cry2) biological activity has been linked to flavin photoreduction via an electron transport chain to the protein surface comprising 3 evolutionarily conserved tryptophan residues known as the "Trp triad." Tryptophan 191-201 cryptochrome 1 Arabidopsis thaliana 25-29 26313597-2 2015 In plants, cryptochrome (cry1, cry2) biological activity has been linked to flavin photoreduction via an electron transport chain to the protein surface comprising 3 evolutionarily conserved tryptophan residues known as the "Trp triad." Tryptophan 225-228 cryptochrome 1 Arabidopsis thaliana 25-29 26313597-6 2015 In the present work we extend these observations to Arabidopsis cryptochrome 1 and demonstrate that Trp triad substitution mutants at W400F and W324F positions which are not photoreduced in vitro can be photoreduced in whole cell extracts, albeit with reduced efficiency. Tryptophan 100-103 cryptochrome 1 Arabidopsis thaliana 64-78 25428980-2 2014 Plant cryptochrome (cry1 and cry2) biological activity has been linked to flavin photoreduction via an electron transport chain comprising three evolutionarily conserved tryptophan residues known as the Trp triad. 4,6-dinitro-o-cresol 74-80 cryptochrome 1 Arabidopsis thaliana 20-24 25450360-4 2014 The photoreceptors cryptochrome 1 (CRY1), phytochrome B (phyB), and phytochrome A (phyA) are also shown to mediate light promotion of anthocyanin accumulation, respectively, whereas their downstream factor COP1, a master negative regulator of photomorphogensis, represses anthocyanin accumulation. Anthocyanins 134-145 cryptochrome 1 Arabidopsis thaliana 19-33 25450360-4 2014 The photoreceptors cryptochrome 1 (CRY1), phytochrome B (phyB), and phytochrome A (phyA) are also shown to mediate light promotion of anthocyanin accumulation, respectively, whereas their downstream factor COP1, a master negative regulator of photomorphogensis, represses anthocyanin accumulation. Anthocyanins 134-145 cryptochrome 1 Arabidopsis thaliana 35-39 25450360-4 2014 The photoreceptors cryptochrome 1 (CRY1), phytochrome B (phyB), and phytochrome A (phyA) are also shown to mediate light promotion of anthocyanin accumulation, respectively, whereas their downstream factor COP1, a master negative regulator of photomorphogensis, represses anthocyanin accumulation. Anthocyanins 272-283 cryptochrome 1 Arabidopsis thaliana 19-33 25450360-4 2014 The photoreceptors cryptochrome 1 (CRY1), phytochrome B (phyB), and phytochrome A (phyA) are also shown to mediate light promotion of anthocyanin accumulation, respectively, whereas their downstream factor COP1, a master negative regulator of photomorphogensis, represses anthocyanin accumulation. Anthocyanins 272-283 cryptochrome 1 Arabidopsis thaliana 35-39 25428980-2 2014 Plant cryptochrome (cry1 and cry2) biological activity has been linked to flavin photoreduction via an electron transport chain comprising three evolutionarily conserved tryptophan residues known as the Trp triad. Tryptophan 170-180 cryptochrome 1 Arabidopsis thaliana 20-24 25428980-2 2014 Plant cryptochrome (cry1 and cry2) biological activity has been linked to flavin photoreduction via an electron transport chain comprising three evolutionarily conserved tryptophan residues known as the Trp triad. Tryptophan 203-206 cryptochrome 1 Arabidopsis thaliana 20-24 21467031-4 2011 Here, we give evidence of a mechanism for the reverse reaction, namely dark reoxidation of protein-bound flavin in Arabidopsis thaliana cryptochrome (AtCRY1) by molecular oxygen that involves formation of a spin-correlated FADH( )-superoxide radical pair. 4,6-dinitro-o-cresol 105-111 cryptochrome 1 Arabidopsis thaliana 150-156 24898692-3 2014 We have studied effects of pH and ATP on the functionally relevant photoreduction of the oxidized FAD cofactor to the semi-reduced FADH( ) radical in isolated Arabidopsis cryptochrome 1 by transient absorption spectroscopy on nanosecond to millisecond timescales. Adenosine Triphosphate 34-37 cryptochrome 1 Arabidopsis thaliana 171-185 24126495-6 2014 The photoreceptor mutants cry1 cry2, phyA, and phyB are hyposensitive to strigolactone analog GR24 under the respective monochromatic light conditions, while cop1 and pif1 pif3 pif4 pif5 (pifq) quadruple mutants are hypersensitive to GR24 in darkness. GR24 strigolactone 73-86 cryptochrome 1 Arabidopsis thaliana 26-30 22855128-0 2012 cry1 and GPA1 signaling genetically interact in hook opening and anthocyanin synthesis in Arabidopsis. Anthocyanins 65-76 cryptochrome 1 Arabidopsis thaliana 0-4 22855128-2 2012 Both cry1 and gpa1 also showed reduced accumulation of anthocyanin under blue light. Anthocyanins 55-66 cryptochrome 1 Arabidopsis thaliana 5-9 22855128-3 2012 These convergent gpa1 and cry1 phenotypes required the presence of sucrose in the growth media and were not additive in the cry1 gpa1 double mutant, suggesting context-dependent signaling convergence between cry1 and GPA1 signaling pathways. Sucrose 67-74 cryptochrome 1 Arabidopsis thaliana 26-30 22855128-4 2012 Both, gpa1 and cry1 mutants showed reduced GTP-binding activity. Guanosine Triphosphate 43-46 cryptochrome 1 Arabidopsis thaliana 15-19 22855128-7 2012 We propose a model where cry1-mediated post-translational modification of GPA1 alters its GTP-binding activity. Guanosine Triphosphate 90-93 cryptochrome 1 Arabidopsis thaliana 25-29 21765176-0 2012 Substitution of a conserved glycine in the PHR domain of Arabidopsis cryptochrome 1 confers a constitutive light response. Glycine 28-35 cryptochrome 1 Arabidopsis thaliana 69-83 21765176-3 2012 Here, we report that CRY1(G380R), which carries a Gly-to-Arg substitution of the highly conserved G380 in the photolyase-related (PHR) domain of Arabidopsis CRY1, shows constitutive CRY1 photoreceptor activity in Arabidopsis. Glycine 50-53 cryptochrome 1 Arabidopsis thaliana 21-25 21765176-3 2012 Here, we report that CRY1(G380R), which carries a Gly-to-Arg substitution of the highly conserved G380 in the photolyase-related (PHR) domain of Arabidopsis CRY1, shows constitutive CRY1 photoreceptor activity in Arabidopsis. Glycine 50-53 cryptochrome 1 Arabidopsis thaliana 157-161 21765176-3 2012 Here, we report that CRY1(G380R), which carries a Gly-to-Arg substitution of the highly conserved G380 in the photolyase-related (PHR) domain of Arabidopsis CRY1, shows constitutive CRY1 photoreceptor activity in Arabidopsis. Glycine 50-53 cryptochrome 1 Arabidopsis thaliana 157-161 21765176-3 2012 Here, we report that CRY1(G380R), which carries a Gly-to-Arg substitution of the highly conserved G380 in the photolyase-related (PHR) domain of Arabidopsis CRY1, shows constitutive CRY1 photoreceptor activity in Arabidopsis. Arginine 57-60 cryptochrome 1 Arabidopsis thaliana 21-25 21765176-3 2012 Here, we report that CRY1(G380R), which carries a Gly-to-Arg substitution of the highly conserved G380 in the photolyase-related (PHR) domain of Arabidopsis CRY1, shows constitutive CRY1 photoreceptor activity in Arabidopsis. Arginine 57-60 cryptochrome 1 Arabidopsis thaliana 157-161 21765176-3 2012 Here, we report that CRY1(G380R), which carries a Gly-to-Arg substitution of the highly conserved G380 in the photolyase-related (PHR) domain of Arabidopsis CRY1, shows constitutive CRY1 photoreceptor activity in Arabidopsis. Arginine 57-60 cryptochrome 1 Arabidopsis thaliana 157-161 22147516-8 2012 The levels of abscisic acid were elevated in cry1 cry2. Abscisic Acid 14-27 cryptochrome 1 Arabidopsis thaliana 45-49 21649509-3 2011 The increase of starch content in illuminated leaves of FV-treated hy1/cry1, hy1/cry2, and hy1/cry1/cry2 Arabidopsis mutants was many-fold lower than that of wild-type (WT) leaves, indicating that MIVOISAP is subjected to photoreceptor-mediated control. Starch 16-22 cryptochrome 1 Arabidopsis thaliana 71-75 21649509-3 2011 The increase of starch content in illuminated leaves of FV-treated hy1/cry1, hy1/cry2, and hy1/cry1/cry2 Arabidopsis mutants was many-fold lower than that of wild-type (WT) leaves, indicating that MIVOISAP is subjected to photoreceptor-mediated control. Starch 16-22 cryptochrome 1 Arabidopsis thaliana 95-99 21467031-4 2011 Here, we give evidence of a mechanism for the reverse reaction, namely dark reoxidation of protein-bound flavin in Arabidopsis thaliana cryptochrome (AtCRY1) by molecular oxygen that involves formation of a spin-correlated FADH( )-superoxide radical pair. Oxygen 171-177 cryptochrome 1 Arabidopsis thaliana 150-156 21467031-4 2011 Here, we give evidence of a mechanism for the reverse reaction, namely dark reoxidation of protein-bound flavin in Arabidopsis thaliana cryptochrome (AtCRY1) by molecular oxygen that involves formation of a spin-correlated FADH( )-superoxide radical pair. Superoxides 231-241 cryptochrome 1 Arabidopsis thaliana 150-156 19327354-3 2009 Here we show in purified preparations of Arabidopsis cry1 that ATP binding induces conformational change independently of light and increases the amount and stability of light-induced flavin radical formation. Adenosine Triphosphate 63-66 cryptochrome 1 Arabidopsis thaliana 53-57 20926618-10 2010 Other nonmutually exclusive potential reasons for the cry1-L407F gain of function are the location of phenylalanine-407 close to three conserved tryptophans, which could change cry1"s photochemical properties, and stabilization of ATP binding, which could extend the lifetime of the signaling state of cry1. Phenylalanine 102-115 cryptochrome 1 Arabidopsis thaliana 54-58 20926618-10 2010 Other nonmutually exclusive potential reasons for the cry1-L407F gain of function are the location of phenylalanine-407 close to three conserved tryptophans, which could change cry1"s photochemical properties, and stabilization of ATP binding, which could extend the lifetime of the signaling state of cry1. Phenylalanine 102-115 cryptochrome 1 Arabidopsis thaliana 177-181 20926618-10 2010 Other nonmutually exclusive potential reasons for the cry1-L407F gain of function are the location of phenylalanine-407 close to three conserved tryptophans, which could change cry1"s photochemical properties, and stabilization of ATP binding, which could extend the lifetime of the signaling state of cry1. Phenylalanine 102-115 cryptochrome 1 Arabidopsis thaliana 177-181 20926618-10 2010 Other nonmutually exclusive potential reasons for the cry1-L407F gain of function are the location of phenylalanine-407 close to three conserved tryptophans, which could change cry1"s photochemical properties, and stabilization of ATP binding, which could extend the lifetime of the signaling state of cry1. Tryptophan 145-156 cryptochrome 1 Arabidopsis thaliana 54-58 20926618-10 2010 Other nonmutually exclusive potential reasons for the cry1-L407F gain of function are the location of phenylalanine-407 close to three conserved tryptophans, which could change cry1"s photochemical properties, and stabilization of ATP binding, which could extend the lifetime of the signaling state of cry1. Tryptophan 145-156 cryptochrome 1 Arabidopsis thaliana 177-181 20926618-10 2010 Other nonmutually exclusive potential reasons for the cry1-L407F gain of function are the location of phenylalanine-407 close to three conserved tryptophans, which could change cry1"s photochemical properties, and stabilization of ATP binding, which could extend the lifetime of the signaling state of cry1. Tryptophan 145-156 cryptochrome 1 Arabidopsis thaliana 177-181 20926618-10 2010 Other nonmutually exclusive potential reasons for the cry1-L407F gain of function are the location of phenylalanine-407 close to three conserved tryptophans, which could change cry1"s photochemical properties, and stabilization of ATP binding, which could extend the lifetime of the signaling state of cry1. Adenosine Triphosphate 231-234 cryptochrome 1 Arabidopsis thaliana 54-58 20926618-10 2010 Other nonmutually exclusive potential reasons for the cry1-L407F gain of function are the location of phenylalanine-407 close to three conserved tryptophans, which could change cry1"s photochemical properties, and stabilization of ATP binding, which could extend the lifetime of the signaling state of cry1. Adenosine Triphosphate 231-234 cryptochrome 1 Arabidopsis thaliana 177-181 20926618-10 2010 Other nonmutually exclusive potential reasons for the cry1-L407F gain of function are the location of phenylalanine-407 close to three conserved tryptophans, which could change cry1"s photochemical properties, and stabilization of ATP binding, which could extend the lifetime of the signaling state of cry1. Adenosine Triphosphate 231-234 cryptochrome 1 Arabidopsis thaliana 177-181 20828134-10 2010 These results are in contrast to plant specific Crys represented by Arabidopsis thaliana Cry1 that carry Asp at the position. Aspartic Acid 105-108 cryptochrome 1 Arabidopsis thaliana 89-93 20053798-9 2010 We also show that systemic acquired resistance (SAR) is positively regulated by CRY1, and that salicylic acid (SA)-induced pathogenesis-related gene PR-1 expression is reduced in the cry1 mutant, but enhanced in CRY1-ovx plants. Salicylic Acid 95-109 cryptochrome 1 Arabidopsis thaliana 183-187 20053798-9 2010 We also show that systemic acquired resistance (SAR) is positively regulated by CRY1, and that salicylic acid (SA)-induced pathogenesis-related gene PR-1 expression is reduced in the cry1 mutant, but enhanced in CRY1-ovx plants. Salicylic Acid 95-109 cryptochrome 1 Arabidopsis thaliana 212-216 20053798-9 2010 We also show that systemic acquired resistance (SAR) is positively regulated by CRY1, and that salicylic acid (SA)-induced pathogenesis-related gene PR-1 expression is reduced in the cry1 mutant, but enhanced in CRY1-ovx plants. Salicylic Acid 48-50 cryptochrome 1 Arabidopsis thaliana 80-84 20053798-10 2010 However, our results indicate that CRY1 only modestly influences SA accumulation and has no effect on hypersensitive cell death. Salicylic Acid 65-67 cryptochrome 1 Arabidopsis thaliana 35-39 19327354-3 2009 Here we show in purified preparations of Arabidopsis cry1 that ATP binding induces conformational change independently of light and increases the amount and stability of light-induced flavin radical formation. 4,6-dinitro-o-cresol 184-190 cryptochrome 1 Arabidopsis thaliana 53-57 17073458-3 2006 Recently, it was found that Arabidopsis cryptochrome 1 (AtCry1) binds ATP and exhibits autokinase activity that is simulated by blue light. Adenosine Triphosphate 70-73 cryptochrome 1 Arabidopsis thaliana 40-54 20031915-6 2008 We further show that cry1 protein expressed in living insect cells responds with greater sensitivity to 380 nm light than to 450 nm, consistent with a light-harvesting antenna pigment that transfers excitation energy to the oxidized flavin of cry1. 4,6-dinitro-o-cresol 233-239 cryptochrome 1 Arabidopsis thaliana 21-25 20031915-6 2008 We further show that cry1 protein expressed in living insect cells responds with greater sensitivity to 380 nm light than to 450 nm, consistent with a light-harvesting antenna pigment that transfers excitation energy to the oxidized flavin of cry1. 4,6-dinitro-o-cresol 233-239 cryptochrome 1 Arabidopsis thaliana 243-247 18065688-6 2007 We also observed that mutants with defects in both plastid-to-nucleus and cry1 signaling exhibited severe chlorophyll deficiencies. Chlorophyll 106-117 cryptochrome 1 Arabidopsis thaliana 74-78 18003924-10 2007 Anthocyanin production in response to blue light was strongly stimulated by nuclear cry1 and, to a lesser extent, by cytoplasmic cry1. Anthocyanins 0-11 cryptochrome 1 Arabidopsis thaliana 84-88 18003924-10 2007 Anthocyanin production in response to blue light was strongly stimulated by nuclear cry1 and, to a lesser extent, by cytoplasmic cry1. Anthocyanins 0-11 cryptochrome 1 Arabidopsis thaliana 129-133 17217468-5 2007 By contrast, cytokinin-dependent stimulation of anthocyanin accumulation occurs only in light, and interacts with the signalling pathway downstream of cryptochrome 1 (CRY1) at the level of transcript accumulation of anthocyanin biosynthetic genes. Anthocyanins 48-59 cryptochrome 1 Arabidopsis thaliana 151-165 17217468-5 2007 By contrast, cytokinin-dependent stimulation of anthocyanin accumulation occurs only in light, and interacts with the signalling pathway downstream of cryptochrome 1 (CRY1) at the level of transcript accumulation of anthocyanin biosynthetic genes. Anthocyanins 48-59 cryptochrome 1 Arabidopsis thaliana 167-171 17217468-5 2007 By contrast, cytokinin-dependent stimulation of anthocyanin accumulation occurs only in light, and interacts with the signalling pathway downstream of cryptochrome 1 (CRY1) at the level of transcript accumulation of anthocyanin biosynthetic genes. Anthocyanins 216-227 cryptochrome 1 Arabidopsis thaliana 151-165 17217468-5 2007 By contrast, cytokinin-dependent stimulation of anthocyanin accumulation occurs only in light, and interacts with the signalling pathway downstream of cryptochrome 1 (CRY1) at the level of transcript accumulation of anthocyanin biosynthetic genes. Anthocyanins 216-227 cryptochrome 1 Arabidopsis thaliana 167-171 17217468-6 2007 Mutants in elongated hypocotyl 5 (hy5), a downstream intermediate in the CRY1 signalling pathway, show a reduced induction of anthocyanin accumulation in blue light by cytokinins, similar to that observed for cryptochrome (cry1) mutants. Anthocyanins 126-137 cryptochrome 1 Arabidopsis thaliana 73-77 17073458-3 2006 Recently, it was found that Arabidopsis cryptochrome 1 (AtCry1) binds ATP and exhibits autokinase activity that is simulated by blue light. Adenosine Triphosphate 70-73 cryptochrome 1 Arabidopsis thaliana 56-62 17075038-0 2006 Cryptochrome-1-dependent execution of programmed cell death induced by singlet oxygen in Arabidopsis thaliana. Singlet Oxygen 71-85 cryptochrome 1 Arabidopsis thaliana 0-14 12730688-2 2003 Using transient absorption spectroscopy, it is demonstrated that the primary light reactions in isolated Arabidopsis thaliana cryptochrome-1 involve intraprotein electron transfer from tryptophan and tyrosine residues to the excited flavin adenine dinucleotide cofactor. Tryptophan 185-195 cryptochrome 1 Arabidopsis thaliana 126-140 15299148-7 2004 Previous in vitro experiments established that the photolyase-like domain of CRY-1 can bind Mg.ATP, and we observe a single molecule of an ATP analog bound in the aforementioned surface cavity, near the bound FAD cofactor. Adenosine Triphosphate 95-98 cryptochrome 1 Arabidopsis thaliana 77-82 15299148-7 2004 Previous in vitro experiments established that the photolyase-like domain of CRY-1 can bind Mg.ATP, and we observe a single molecule of an ATP analog bound in the aforementioned surface cavity, near the bound FAD cofactor. Adenosine Triphosphate 139-142 cryptochrome 1 Arabidopsis thaliana 77-82 15299148-7 2004 Previous in vitro experiments established that the photolyase-like domain of CRY-1 can bind Mg.ATP, and we observe a single molecule of an ATP analog bound in the aforementioned surface cavity, near the bound FAD cofactor. Flavin-Adenine Dinucleotide 209-212 cryptochrome 1 Arabidopsis thaliana 77-82 14535885-5 2003 Many of the cry1-dependent genes encoded kinases, transcription factors, cell cycle regulators, cell wall metabolism enzymes, gibberellic acid (GA) biosynthesis enzymes, and auxin response factors. gibberellic acid 126-142 cryptochrome 1 Arabidopsis thaliana 12-16 14535885-5 2003 Many of the cry1-dependent genes encoded kinases, transcription factors, cell cycle regulators, cell wall metabolism enzymes, gibberellic acid (GA) biosynthesis enzymes, and auxin response factors. gibberellic acid 144-146 cryptochrome 1 Arabidopsis thaliana 12-16 14535885-7 2003 Inhibiting GA4 biosynthesis with a 3beta-hydroxylase inhibitor (Ca-prohexadione) restored wild-type response kinetics in cry1 and completely suppressed its long-hypocotyl phenotype in blue light. ca-prohexadione 64-79 cryptochrome 1 Arabidopsis thaliana 121-125 14535885-8 2003 Co-treatment of cry1 seedlings with Ca-prohexadione plus GA4 completely reversed the effects of the inhibitor, restoring the long-hypocotyl phenotype typical of the mutant. ca-prohexadione 36-51 cryptochrome 1 Arabidopsis thaliana 16-20 12846824-3 2003 Here, we report a novel ATP binding and autophosphorylation activity associated with Arabidopsis cry1 protein purified from a baculovirus expression system. Adenosine Triphosphate 24-27 cryptochrome 1 Arabidopsis thaliana 97-101 12730688-2 2003 Using transient absorption spectroscopy, it is demonstrated that the primary light reactions in isolated Arabidopsis thaliana cryptochrome-1 involve intraprotein electron transfer from tryptophan and tyrosine residues to the excited flavin adenine dinucleotide cofactor. Tyrosine 200-208 cryptochrome 1 Arabidopsis thaliana 126-140 12730688-2 2003 Using transient absorption spectroscopy, it is demonstrated that the primary light reactions in isolated Arabidopsis thaliana cryptochrome-1 involve intraprotein electron transfer from tryptophan and tyrosine residues to the excited flavin adenine dinucleotide cofactor. Flavin-Adenine Dinucleotide 233-260 cryptochrome 1 Arabidopsis thaliana 126-140 9733523-3 1998 phyA was the major photoreceptor/effector for most far-red-light responses, although phyB and cry1 modulated anthocyanin accumulation in a phyA-dependent manner. Anthocyanins 109-120 cryptochrome 1 Arabidopsis thaliana 94-98 12068118-5 2002 In both green- and norflurazon-treated (chlorophyll-deficient) seedlings, cryptochrome activity is fairly uniform throughout its range of maximal response (390-480 nm), with no sharply defined peak at 450 nm; however, activity at longer wavelengths was disproportionately enhanced in CRY1-overexpressing seedlings as compared with wild type. norflurazone 19-30 cryptochrome 1 Arabidopsis thaliana 284-288 9733523-4 1998 phyB was the major photoreceptor in red light, although cry1 acted as a phyA/phyB-dependent modulator of chlorophyll accumulation under these conditions. Chlorophyll 105-116 cryptochrome 1 Arabidopsis thaliana 56-60 8547814-0 1995 Extension-growth responses and expression of flavonoid biosynthesis genes in the Arabidopsis hy4 mutant. Flavonoids 45-54 cryptochrome 1 Arabidopsis thaliana 93-96 9489009-7 1998 This is in contrast to the reduced anthocyanin accumulation displayed by a mutant lacking the HY4 blue-light receptor, as hy4 displayed reduced expression of the above enzymes. Anthocyanins 35-46 cryptochrome 1 Arabidopsis thaliana 94-97 9490743-5 1998 Hybrid receptor proteins mediate functions similar to cry1 and include inhibition of hypocotyl elongation and blue light-dependent anthocyanin accumulation; differences in activity appear to be correlated with differing protein stability. Anthocyanins 131-142 cryptochrome 1 Arabidopsis thaliana 54-58 11542766-4 1997 As the action spectrum for phototropism resembles the absorption spectrum of a flavoprotein, flavoproteins are attractive candidates at present, especially since the CRY1 photoreceptor in Arabidopsis thaliana that mediates blue light-dependent hypocotyl growth suppression has flavin adenine dinucleotide as one of its two chromophores. Flavin-Adenine Dinucleotide 277-304 cryptochrome 1 Arabidopsis thaliana 166-170 8528277-5 1995 CRY1 was originally defined as the photoreceptor responsible for blue-light-mediated inhibition of hypocotyl elongation and we now report that anthocyanin accumulation in germinating seedlings is an additional phenotype under the control of this photoreceptor--this is shown to be mediated in part by modulation of mRNA levels of chalcone synthase, one of the anthocyanin biosynthetic enzymes. Anthocyanins 143-154 cryptochrome 1 Arabidopsis thaliana 0-4 8528277-5 1995 CRY1 was originally defined as the photoreceptor responsible for blue-light-mediated inhibition of hypocotyl elongation and we now report that anthocyanin accumulation in germinating seedlings is an additional phenotype under the control of this photoreceptor--this is shown to be mediated in part by modulation of mRNA levels of chalcone synthase, one of the anthocyanin biosynthetic enzymes. Anthocyanins 360-371 cryptochrome 1 Arabidopsis thaliana 0-4 9107032-1 1997 Blue-light responses in higher plants are mediated by specific photoreceptors, which are thought to be flavoproteins; one such flavin-type blue-light receptor, CRY1 (for cryptochrome), which mediates inhibition of hypocotyl elongation and anthocyanin biosynthesis, has recently been characterized. Anthocyanins 239-250 cryptochrome 1 Arabidopsis thaliana 160-164 9107032-5 1997 It was concluded that CRY1-mediated inhibition of hypocotyl elongation and anthocyanin production requires active phytochrome for full expression, and that this requirement can be supplied by low levels of either phyA or phyB. Anthocyanins 75-86 cryptochrome 1 Arabidopsis thaliana 22-26 8953250-7 1996 In addition, transgenic plants overexpressing CRY1 showed increased anthocyanin accumulation in response to blue, UV-A, and green light in a fluence rate-dependent manner. Anthocyanins 68-79 cryptochrome 1 Arabidopsis thaliana 46-50 7638620-0 1995 Association of flavin adenine dinucleotide with the Arabidopsis blue light receptor CRY1. Flavin-Adenine Dinucleotide 15-42 cryptochrome 1 Arabidopsis thaliana 84-88 7638620-2 1995 CRY1 is demonstrated here to noncovalently bind stoichiometric amounts of flavin adenine dinucleotide (FAD). Flavin-Adenine Dinucleotide 74-101 cryptochrome 1 Arabidopsis thaliana 0-4 7638620-2 1995 CRY1 is demonstrated here to noncovalently bind stoichiometric amounts of flavin adenine dinucleotide (FAD). Flavin-Adenine Dinucleotide 103-106 cryptochrome 1 Arabidopsis thaliana 0-4 7638620-3 1995 The redox properties of FAD bound by CRY1 include an unexpected stability of the neutral radical flavosemiquinone (FADH.). Flavin-Adenine Dinucleotide 24-27 cryptochrome 1 Arabidopsis thaliana 37-41 7638620-3 1995 The redox properties of FAD bound by CRY1 include an unexpected stability of the neutral radical flavosemiquinone (FADH.). flavosemiquinone 97-113 cryptochrome 1 Arabidopsis thaliana 37-41 7638620-4 1995 The absorption properties of this flavosemiquinone provide a likely explanation for the additional sensitivity exhibited by CRY1-mediated responses in the green region of the visible spectrum. flavosemiquinone 34-50 cryptochrome 1 Arabidopsis thaliana 124-128 8547814-5 1995 Anthocyanin formation and the expression of several flavonoid biosynthesis genes is stimulated by blue light in the wild type but to a much lower extent in hy4. Anthocyanins 0-11 cryptochrome 1 Arabidopsis thaliana 156-159 8547814-5 1995 Anthocyanin formation and the expression of several flavonoid biosynthesis genes is stimulated by blue light in the wild type but to a much lower extent in hy4. Flavonoids 52-61 cryptochrome 1 Arabidopsis thaliana 156-159 8232555-7 1993 As photolyases are a rare class of flavoprotein that catalyse blue-light-dependent reactions, the protein encoded by HY4 has a structure consistent with that of a flavin-type blue-light photoreceptor. 4,6-dinitro-o-cresol 163-169 cryptochrome 1 Arabidopsis thaliana 117-120 34358729-4 2021 In addition, hy4 HBL plants demonstrated lowered UAP and carotenoid contents as well as lower activity of APX and GPX enzymes. Carotenoids 57-67 cryptochrome 1 Arabidopsis thaliana 13-16 33971366-5 2021 Here, we show that blue light represses GA-induced degradation of DELLA proteins (DELLAs), which are key negative regulators in the GA signaling pathway, via CRY1, thereby inhibiting the GA response during hypocotyl elongation. Gallium 40-42 cryptochrome 1 Arabidopsis thaliana 158-162 33971366-5 2021 Here, we show that blue light represses GA-induced degradation of DELLA proteins (DELLAs), which are key negative regulators in the GA signaling pathway, via CRY1, thereby inhibiting the GA response during hypocotyl elongation. Gallium 132-134 cryptochrome 1 Arabidopsis thaliana 158-162 33971366-5 2021 Here, we show that blue light represses GA-induced degradation of DELLA proteins (DELLAs), which are key negative regulators in the GA signaling pathway, via CRY1, thereby inhibiting the GA response during hypocotyl elongation. Gallium 132-134 cryptochrome 1 Arabidopsis thaliana 158-162 33971366-6 2021 Data from our in vitro and in vivo biochemical analyses demonstrate that CRY1 physically interacts with GA receptors-GA INSENSITIVE DWARF 1 proteins (GID1s)-and DELLAs in a blue light-dependent manner. Gallium 104-106 cryptochrome 1 Arabidopsis thaliana 73-77 33971366-9 2021 Taken together, our findings demonstrate that CRY1 signals by stabilizing DELLAs through binding and inactivating GID1s and provide new insight into the mechanism by which blue light antagonizes the function of GA in photomorphogenesis. Gallium 211-213 cryptochrome 1 Arabidopsis thaliana 46-50 34358729-6 2021 We assume that the deficiency in cryptochrome 1 under HIL irradiation disrupts the interaction between HY5 and HFR1 transcription factors and photoreceptors, which affects the transcription of light-induced genes, such as CAB1, PSY and PAL1 linked to carotenoid and flavonoid biosynthesis. Carotenoids 251-261 cryptochrome 1 Arabidopsis thaliana 33-47 34358729-6 2021 We assume that the deficiency in cryptochrome 1 under HIL irradiation disrupts the interaction between HY5 and HFR1 transcription factors and photoreceptors, which affects the transcription of light-induced genes, such as CAB1, PSY and PAL1 linked to carotenoid and flavonoid biosynthesis. Flavonoids 266-275 cryptochrome 1 Arabidopsis thaliana 33-47 34358729-7 2021 It was concluded that PA stress resistance in WT and hy4 plants depends on the light intensity and reduced stress resistance of hy4 at HBL, is likely linked to low UAP and carotenoid contents as well as lowered APX and GPX enzyme activities in hy4 mutants. Protactinium 22-24 cryptochrome 1 Arabidopsis thaliana 53-56 34358729-7 2021 It was concluded that PA stress resistance in WT and hy4 plants depends on the light intensity and reduced stress resistance of hy4 at HBL, is likely linked to low UAP and carotenoid contents as well as lowered APX and GPX enzyme activities in hy4 mutants. Protactinium 22-24 cryptochrome 1 Arabidopsis thaliana 128-131 34358729-7 2021 It was concluded that PA stress resistance in WT and hy4 plants depends on the light intensity and reduced stress resistance of hy4 at HBL, is likely linked to low UAP and carotenoid contents as well as lowered APX and GPX enzyme activities in hy4 mutants. Protactinium 22-24 cryptochrome 1 Arabidopsis thaliana 244-247 34358729-7 2021 It was concluded that PA stress resistance in WT and hy4 plants depends on the light intensity and reduced stress resistance of hy4 at HBL, is likely linked to low UAP and carotenoid contents as well as lowered APX and GPX enzyme activities in hy4 mutants. Carotenoids 172-182 cryptochrome 1 Arabidopsis thaliana 53-56 34358729-7 2021 It was concluded that PA stress resistance in WT and hy4 plants depends on the light intensity and reduced stress resistance of hy4 at HBL, is likely linked to low UAP and carotenoid contents as well as lowered APX and GPX enzyme activities in hy4 mutants. Carotenoids 172-182 cryptochrome 1 Arabidopsis thaliana 128-131 34778751-0 2021 The blue light receptor CRY1 interacts with GID1 and DELLA proteins to repress gibberellin signaling and plant growth. Gibberellins 79-90 cryptochrome 1 Arabidopsis thaliana 24-28