PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 29263137-3 2018 In the present study, Ninj1 was found highly expressed in endothelial cells in Type 2 diabetic mice and increased in high-glucose (HG) cultured HUVECs. Glucose 122-129 ninjurin 1 Mus musculus 22-27 30354207-8 2018 Alternatively, pericyte-specific Ninj1 knockout was induced by tamoxifen treatment of NG2-CreERT/Ninj1-flox mice. Tamoxifen 63-72 ninjurin 1 Mus musculus 33-38 30354207-8 2018 Alternatively, pericyte-specific Ninj1 knockout was induced by tamoxifen treatment of NG2-CreERT/Ninj1-flox mice. Tamoxifen 63-72 ninjurin 1 Mus musculus 97-102 27127177-7 2016 After AOM and DSS treatment, ninjurin1 tg mice developed fewer and smaller tumors compared with wild-type (wt) mice. Dextran Sulfate 14-17 ninjurin 1 Mus musculus 29-38 27815839-7 2017 Moreover, the disruption of Ninj1 leads to glutamatergic abnormalities, including increased ionotropic glutamate receptors but reduced glutamate levels. Glutamic Acid 43-52 ninjurin 1 Mus musculus 28-33 27815839-8 2017 Furthermore, chronic treatment with fluoxetine, a drug reportedly ameliorates compulsive behaviors in mice, prevents progression of hair loss and alleviates the compulsive grooming and anxiety-like behavior of Ninj1 KO mice. Fluoxetine 36-46 ninjurin 1 Mus musculus 210-215 25502067-5 2015 Furthermore, phenyl-beta-D-glucopyranoside abolished increased adhesion, ninjurin 1 (Ninj1) expression, and matrix metalloproteinase (MMP) activity induced by endotoxin treatment. phenylglucoside 13-42 ninjurin 1 Mus musculus 73-83 26677008-6 2016 In addition, knockdown experiments using Ninj1 siRNA resulted in decreased nitric oxide (NO) and tumor necrosis factor-alpha (TNFalpha) secretion upon LPS treatment in Raw264.7 cells. Nitric Oxide 75-87 ninjurin 1 Mus musculus 41-46 25502067-5 2015 Furthermore, phenyl-beta-D-glucopyranoside abolished increased adhesion, ninjurin 1 (Ninj1) expression, and matrix metalloproteinase (MMP) activity induced by endotoxin treatment. phenylglucoside 13-42 ninjurin 1 Mus musculus 85-90 24127072-9 2014 Additionally, endotoxin-induced adhesion of macrophages and the expression level of ninjurin1 (Ninj1) were decreased by chlorogenic acid. Chlorogenic Acid 120-136 ninjurin 1 Mus musculus 84-93 24979788-4 2014 Here, we demonstrate in streptozotocin-induced diabetic mice that inhibition of the Ninj1 pathway by administering Ninj1-neutralizing antibody (Ninj1-Ab) or by using Ninj1-knockout mice successfully restored erectile function through enhanced penile angiogenesis and neural regeneration. Streptozocin 24-38 ninjurin 1 Mus musculus 84-89 24127072-9 2014 Additionally, endotoxin-induced adhesion of macrophages and the expression level of ninjurin1 (Ninj1) were decreased by chlorogenic acid. Chlorogenic Acid 120-136 ninjurin 1 Mus musculus 95-100 23142597-6 2012 Furthermore, Matrix Metalloproteinase (MMP) 9 was responsible for Ninjurin1 cleavage between Leu(56) and Leu(57). Leucine 93-96 ninjurin 1 Mus musculus 66-75 23142597-6 2012 Furthermore, Matrix Metalloproteinase (MMP) 9 was responsible for Ninjurin1 cleavage between Leu(56) and Leu(57). Leucine 105-108 ninjurin 1 Mus musculus 66-75 23061002-3 2012 In the present study, we determined the differential expression of Ninjurin 1 in penile tissue of streptozotocin (STZ)-induced diabetic mice with ED. Streptozocin 98-112 ninjurin 1 Mus musculus 67-77 23061002-3 2012 In the present study, we determined the differential expression of Ninjurin 1 in penile tissue of streptozotocin (STZ)-induced diabetic mice with ED. Streptozocin 114-117 ninjurin 1 Mus musculus 67-77 23061002-9 2012 In the in vitro study in MCECs, Ninjurin 1 expression was also significantly increased by the high-glucose condition and was returned to baseline levels by treatment with insulin. Glucose 99-106 ninjurin 1 Mus musculus 32-42 22487852-9 2012 Additionally, arbutin suppressed the adhesion activity of BV2 cells and the expression of an important adhesion molecule, Ninj1, in LPS-stimulated murine BV2 cells. Arbutin 14-21 ninjurin 1 Mus musculus 122-127 33961504-10 2021 NG2-CreER/Ninj1loxp mice were treated with tamoxifen (Tam) to induce deletion of Ninj1 in pericyte (Ninj1KO). Tamoxifen 43-52 ninjurin 1 Mus musculus 100-107 33961504-10 2021 NG2-CreER/Ninj1loxp mice were treated with tamoxifen (Tam) to induce deletion of Ninj1 in pericyte (Ninj1KO). Tamoxifen 54-57 ninjurin 1 Mus musculus 100-107 34864308-5 2022 Cristacarpin decreased cell adhesion of macrophages through downregulation of the expression of Ninjurin1 and matrix metalloproteinases. cristacarpin 0-12 ninjurin 1 Mus musculus 96-105 34974535-0 2022 miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1. mir-125a-5p 0-11 ninjurin 1 Mus musculus 77-86 34974535-6 2022 Among them, miR-125a-5p showed a profound inhibitory effect on Ninj1 expression, and miR-125a-5p mimic suppressed the cell-to-cell and cell-to-matrix adhesion of macrophages and expression of pro-inflammatory factors mediated by Ninj1. mir-125a-5p 12-23 ninjurin 1 Mus musculus 63-68 34974535-6 2022 Among them, miR-125a-5p showed a profound inhibitory effect on Ninj1 expression, and miR-125a-5p mimic suppressed the cell-to-cell and cell-to-matrix adhesion of macrophages and expression of pro-inflammatory factors mediated by Ninj1. mir-125a-5p 12-23 ninjurin 1 Mus musculus 229-234 34974535-6 2022 Among them, miR-125a-5p showed a profound inhibitory effect on Ninj1 expression, and miR-125a-5p mimic suppressed the cell-to-cell and cell-to-matrix adhesion of macrophages and expression of pro-inflammatory factors mediated by Ninj1. mir-125a-5p 85-96 ninjurin 1 Mus musculus 229-234